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Keratometric Change After XEN, Trabeculectomy and Tube Shunts Study Overview ================= Brief Summary ----------------- The main goal of this study is to assess the severity of postoperative corneal astigmatism induced by implantation of the XEN Gel Stent compared to that induced by traditional filtering surger...	ctgov
Flares of Low Back Pain With Activity Research Study Study Overview ================= Brief Summary ----------------- Low back pain (LBP) is the most common cause of disability worldwide. Although general activity is encouraged in the treatment of LBP, there is limited empirical information available on the specific t...	ctgov
Heart Exercise And Resistance Training - Peer Lead ActivitY Study Overview ================= Brief Summary ----------------- Numerous studies show that regular physical activity / exercise significantly improves exercise tolerance as well as clinical outcomes in cardiovascular disease (CVD). Exercise as a reliable adj...	ctgov
The DIEP Flap as a Model of Ischemia-Reperfusion: an Intervention Study Study Overview ================= Brief Summary ----------------- The investigators will examine whether administration of certain medications will decrease or prevent ischemia-reperfusion injury. Official Title ----------------- The DIEP Flap as ...	ctgov
Internet-based Depression Treatment: Differential Efficacy of Different Therapeutic Components Study Overview ================= Brief Summary ----------------- The objective of the present project is to study the differential effectiveness of three brief self-applied via the Internet interventions for mild to moderate...	ctgov
Nurturing Healthy Teachers Study Overview ================= Brief Summary ----------------- The purpose of this trial is to compare the impact of a fruit and vegetable access plus nutrition education intervention to a nutrition education-only control on the health, well-being, and food security of early care and educa...	ctgov
Equistasi and Gait in Hemiparesis Study Overview ================= Brief Summary ----------------- The purpose of the study is to evaluate the effect of Equistasi device on quantitative and qualitative gait characteristics in patients affected by hemiparesis. Official Title ----------------- Efficacy of Equistasi on ...	ctgov
Peer Genetic Coaches for Enhancing Genetic Testing Awareness, Navigation, and Delivery Among African American Men With Metastatic Prostate Cancer, The EXPAND Network Study Overview ================= Brief Summary ----------------- This trial evaluates whether a network of peer genetic coaches is useful for addressing ...	ctgov
AC220 for Children With Relapsed/Refractory ALL or AML Study Overview ================= Brief Summary ----------------- This is a phase I study of the investigational drug AC220 combined with cytarabine and etoposide in pediatric patients with relapsed acute lymphoblastic leukemia (ALL) and acute myelogenous leukemia ...	ctgov
Ketogenic Diet and Chemotherapy in Affecting Recurrence in Patients With Stage IV Breast Cancer Study Overview ================= Brief Summary ----------------- This pilot clinical trial studies how well a ketogenic diet and chemotherapy work in affecting the return of cancer in patients with stage IV breast cancer. K...	ctgov
ThinkingFit: Combined Physical, Cognitive and Social Treatment in Mild Cognitive Impairment (MCI) Study Overview ================= Brief Summary ----------------- Dementia is serious problem and around 700 000 people are affected in the UK alone. Currently there is no cure however early diagnosis and effective treatme...	ctgov
Prevalence of Gastroesophageal Reflux Disease (GERD) in Patients With Upper Gastrointestinal Track (GIT) Symptoms in Thailand Study Overview ================= Brief Summary ----------------- This is a prospective , epidemiological, multi-centre, phase IV study, approximately 5,000 patients who suffer with upper gastro...	ctgov
Efficacy of Early Tracheostomy to Reduce Incidence of Ventilator Acquired Pneumonia (VAP) Study Overview ================= Brief Summary ----------------- The study aims to assess early (one to three days after intubation) tracheostomy effectiveness in terms of reduction in ventilator associated pneumonia (VAP) incide...	ctgov
Study of Levalbuterol, Racemic Albuterol and Placebo in Subjects Twelve Years of Age and Older With Asthma Study Overview ================= Brief Summary ----------------- The primary objective of this study is to investigate the efficacy of levalbuterol 90 ug (2 actuations, 45 ug each) versus placebo (2 actuations) i...	ctgov
Immune Boost In Non-Small Cell Lung Cancer Study Overview ================= Brief Summary ----------------- Insufficient migration and activation of tumour specific effector T cells seems to be the one important reason for inadequate host anti-tumour immune response. Ionizing radiation can induce a variety of immune r...	ctgov
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling Study Overview ================= Brief Summary ----------------- After completing all screening evaluations, subjects will receive unblinded N-Acetyl Cysteine 600 mg/day for 2 weeks. The dose will be raised to 1200 mg/day at visit 4 and to 1800 mg/day a...	ctgov
Study of Jaktinib In Patients With Myelofibrosis Who Were Relapsed or Refractory of Ruxolitinib Treatment. Study Overview ================= Brief Summary ----------------- This was a phase 2, single-arm, open-label, non-randomised, multicentre, study to evaluate the efficacy and safety of Jaktinib in patients with mye...	ctgov
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees Study Overview ================= Brief Summary ----------------- INTRODUCTION Trauma-affected refugees are at high risk of developing mental health problems including post-traumatic stress disorder (PTSD) and depression. In additio...	ctgov
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma Study Overview ================= Brief Summary ----------------- Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemo...	ctgov
Phase 1 TheraSphere + Everolimus With Neuroendocrine Tumors (NETs) + Liver Only or Liver Dominant Disease Study Overview ================= Brief Summary ----------------- The goal of this clinical research study is to find the highest tolerable dose of the combination of everolimus with TheraSphere that can be given t...	ctgov
Trehalose in Subjects With Neuronal Ceroid Lipofuscinoses Study Overview ================= Brief Summary ----------------- Neuronal Ceroid Lipofuscinoses (NCL) or Batten's disease are the most common juvenile neurodegenerative disease, characterized by early blindness, movement disorders, cognitive and behavioral impa...	ctgov
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States Study Overview ================= Brief Summary ----------------- The primary aim is to determine the effect of participant and provider knowledge of a positive APOL1 status and accompanying guideline based clinical decision su...	ctgov
Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam Study Overview ================= Brief Summary ----------------- This study is a multi-centre, open-label randomised trial to assess the efficacy, safety and tolerability of the Triple ACT artemether-lumefantrine+amodiaquine (AL+AQ) compared...	ctgov
Gastric Emptying of Water and Sports Drink in Labor Study Overview ================= Brief Summary ----------------- To determine the half time of the emptying of the stomach of women in early labor with and without epidural pain relief when drinking either water or a carbohydrate-based sports drink. Detailed Descrip...	ctgov
Quality of Life in Patients Undergoing Colorectal Resection for Deep Infiltrating Endometriosis Study Overview ================= Brief Summary ----------------- The aim of this study is to evaluate the quality of life of patients undergoing colorectal resection for deep infiltrating endometriosis of the bowel. Questio...	ctgov
Susceptibility of Human Volunteers With Different Histo-Blood With Different Histo-Blood Group Antigens to Norovirus Study Overview ================= Brief Summary ----------------- Objectives: To evaluate the role of human histo-blood group antigens in susceptibility to Norovirus infections. Description of Study Desi...	ctgov
3D Bioprinted Models for Predicting Chemotherapy Response in Colorectal Cancer With/Without Liver Metastases Study Overview ================= Brief Summary ----------------- The therapeutic regimens of adjuvant and neoadjuvant chemotherapy for colorectal cancer (CRC) remain largely relied on clinical experience, and t...	ctgov
Study of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal Cancer Study Overview ================= Brief Summary ----------------- The purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epiderm...	ctgov
Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid Tumors Study Overview ================= Brief Summary ----------------- Clinical trial of PM01183 in combination with paclitaxel, with or without bevacizumab, in patients with solid tumors ...	ctgov
Focused Assessment With Sonography in Trauma Study Overview ================= Brief Summary ----------------- The study evaluates the knowledge and attitude about Focused Assessment with Sonography in Trauma examination among medical students and medical staff in Poland. Official Title ----------------- Prepared for ...	ctgov
Schizotypal Personality Disorder Risperidone Study Overview ================= Brief Summary ----------------- Neurophysiological indices of self-monitoring were assessed in a group of patients with Schizotypal Personality Disorder (SPD) and a control group. Both groups were assessed after the administration of risperi...	ctgov
Evaluation of the Effect of Sodium Bicarbonate Water on Blood Pressure in Normotensive Subjects Study Overview ================= Brief Summary ----------------- ROX_TENSIO18 is a randomised cross-over trial and the main objective is to evaluate the effect of daily consumption of sodium bicarbonate water for 15 days on...	ctgov
Hyperbaric Oxygen Therapy for Ulcerative Colitis Flares Study Overview ================= Brief Summary ----------------- Ulcerative colitis (UC) is a chronic inflammatory bowel disease associated with recurrent mucosal inflammation. Clinically, the disease is characterized by bloody diarrhea, abdominal pain, and const...	ctgov
Using Telephone Counselling to Improve Exercise Participation in Hematologic Cancer Survivors Study Overview ================= Brief Summary ----------------- This study evaluates the impact of a 12-week theory-based exercise telephone counselling program (versus a self-directed exercise group) on closing the exercise...	ctgov
Safety, Immunogenicity and Efficacy of GSK S. Aureus Candidate Vaccine (GSK3878858A) When Administered to Healthy Adults (Dose-escalation) and to Adults 18 to 64 Years of Age With a Recent S. Aureus Skin and Soft Tissue Infection (SSTI) Study Overview ================= Brief Summary ----------------- Safety, immunogen...	ctgov
Randomised Evaluation of COVID-19 Therapy (RECOVERY) in Children With PIMS-TS in Switzerland (SWISSPED-RECOVERY) Study Overview ================= Brief Summary ----------------- The study is to provide reliable estimates of the effect of study treatment on hospital length of stay through to 28 days after randomisation...	ctgov
9-ING-41 Plus Retifanlimab and Gemcitabine/Nab-Paclitaxel in Patients With Advanced Pancreatic Adenocarcinoma Study Overview ================= Brief Summary ----------------- This trial examines how Pancreatic Adenocarcinoma reacts to the addition of 9-ING-41 and retifanlimab to the standard of care chemotherapy treat...	ctgov
Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -A Pilot Study Study Overview ================= Brief Summary ----------------- This is a multi-center, prospective, non-randomized, open-label, exploratory clinical investigation performed to evaluate safety and effectiveness of t...	ctgov
A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors Study Overview ================= Brief Summary ----------------- This is a dose escalation study that will assess the safety and efficacy of LCL161 in combination with weekly paclitaxel in adult patients with advanced ...	ctgov
Comparing Efficacy and Safety of Inhaled SNG001 to Placebo Study Overview ================= Brief Summary ----------------- When people with asthma get respiratory virus such as a cold or flu it often increases asthma symptoms. The investigators will test the study medication to find out if it can prevent the virus sp...	ctgov
Observational Study of Ibrutinib Use in CLL Study Overview ================= Brief Summary ----------------- IB-RU-SCOPE is a routine-clinical practice oriented cohort observational study of ibrutinib efficacy and safety in approx. 70 patients with chronic lymphocytic leukemia in the Russian Federation Detailed Descr...	ctgov
Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block? Study Overview ================= Brief Summary ----------------- Hemi-diaphragmatic palsy is a common undesirable effect of interscalene block, with an incidence of up to 100%. Mechanism of palsy is thoug...	ctgov
Effect of Medicago Sativa on Oral Glucose Tolerance in Healthy Adults Study Overview ================= Brief Summary ----------------- Previous preclinical investigations have found that Medicago sativa promotes the decrease of glucose concentrations. To evaluate the acute effect of Medicago sativa administration on g...	ctgov
The Comparison of Oxidative Stress Between Inhalation Anesthetics Study Overview ================= Brief Summary ----------------- Oxidative stress is an unavoidable event during cardiac surgery. Isoprostanes have been demonstrated to be a reliable biomarker for the evaluation of oxidative stress in vivo.The aims of t...	ctgov
Mindfulness Mobile App to Reduce Adolescent Substance Use Study Overview ================= Brief Summary ----------------- Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, pe...	ctgov
Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia Study Overview ================= Brief Summary ----------------- This study will determine the efficacy of corneal collagen crosslinking (CXL) combined with Intacs for the treatment of keratoconus and corneal ectasia. The goal of CXL is to decrease t...	ctgov
JNJ-40346527 in Treating Participants With Relapsed or Refractory Acute Myeloid Leukemia Study Overview ================= Brief Summary ----------------- This phase II trial studies how well edicotinib (JNJ-40346527) works in treating participants with acute myeloid leukemia that has come back or does not respond to t...	ctgov
The Effect of Erigeron Injection on Acute Cerebral Infarction Serum VEGF, MMP-9 and EPC Levels Study Overview ================= Brief Summary ----------------- To study the effects of Erigeron Injection on human serum VEGF, MMP-9 and EPC levels after acute cerebral infarction,test is made by random double-blind contro...	ctgov
Evaluating PVI Using CMR Study Overview ================= Brief Summary ----------------- Using state of the art cardiac magnetic resonance imaging techniques, characterization of ablation lesions in the early phase after pulmonary vein isolation ablation in atrial fibrillation patients, and relate findings to the abl...	ctgov
SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma Study Overview ================= Brief Summary ----------------- Background: Malignant mesothelioma is a form of cancer that develops on the protective lining that covers the body's internal organs. It most often occurs on the lining of the lungs and chest wa...	ctgov
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology Study Overview ================= Brief Summary ----------------- Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival <20%). Endoscopic ultrasound with fine need...	ctgov
Prevention of Inappropriate ICD Shocks Study Overview ================= Brief Summary ----------------- The aim of the present study is to investigate whether increasing detection zones can effectively reduce inappropriate ICD therapies in primary prevention patients. Conditions ----------------- Inappropriate ICD Th...	ctgov
Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme Study Overview ================= Brief Summary ----------------- This study aims to treat patients who have been diagnosed with brain cancer including glioblastoma multiforme (GBM). The treatment combines two different approaches to fight cancer: immune...	ctgov
Efficacy and Safety of JTT-705 300, 600 And 900mg in Comparison With Placebo in Patients With Type II Hyperlipidaemia Study Overview ================= Brief Summary ----------------- To demonstrate the effect of JTT-705 doses from 300 mg to 900 mg on the elevation of HDL-C and on the inhibition of CETP activity versus...	ctgov
Advanced Approach to Arterial Stiffness Study Overview ================= Brief Summary ----------------- The aim of the 3A Study is to assess the role of MetS on the arterial mechanics and vascular health in different age groups using the Cardio Ankle Vascular Index (CAVI) of the Vasera system and the classic carotid-...	ctgov
Dynamic Evaluation of Ankle Joint and Muscle Mechanics in Children With Spastic Equinus Deformity Due to Cerebral Palsy Study Overview ================= Brief Summary ----------------- This research will lead to the first evaluation of intrinsic and dynamic joint and muscle mechanics of equinus in cerebral palsy. It w...	ctgov
Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder Study Overview ================= Brief Summary ----------------- Background: Alcohol Use Disorder (AUD) is a complex psychiatric disorder, involving several brain areas and neurocircuits. Transcranial Direct Current St...	ctgov
The Effect of Methylphenidate Versus Placebo on State Anxiety in Children With Attention Deficit Hyperactivity Disorder. Study Overview ================= Brief Summary ----------------- The purpose of the study is to explore the effect of methylphenidate on state anxiety in children with attention deficit hyperactivit...	ctgov
A Vignette-based Randomized Controlled Trial to Evaluate the Impact of Research Climate on Research Practices of Doctoral Students Study Overview ================= Brief Summary ----------------- This study aims to evaluate the impact of research climate on PhD students' research practice (i.e., an environment where t...	ctgov
Extracorporeal Photopheresis and Early Cardiac Graft Vasculopathy Study Overview ================= Brief Summary ----------------- Heart transplantation is a golden standard for the treatment of terminal heart failure. The major cause of death in late posttransplant period is cardiac allograft vasculopathy (CAV). This...	ctgov
Immune Response to C.Difficile Infection Study Overview ================= Brief Summary ----------------- The protocol aims to address the basic mechanisms of Clostridium difficile pathogenesis by identifying how a Th 17 response impacts severity of C. difficile infection and how Type II immunity protects the gut from...	ctgov
HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies Study Overview ================= Brief Summary ----------------- HEM-iSMART is a master protocol which investigates multiple investigational medicinal products in children, adolescents and young a...	ctgov
Vietnamese Caregiver Intervention Study Study Overview ================= Brief Summary ----------------- The purpose of this study is to develop and implement a culturally-appropriate intervention to reduce stress in Vietnamese dementia caregivers. A pilot intervention will be done to test the feasibility and acceptab...	ctgov
Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure Study Overview ================= Brief Summary ----------------- The purpose of this study is to determine whether continuing or discontinuing furosemide (a diuretic) on the day of elective noncardiac surgery for those who take furo...	ctgov
Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients Study Overview ================= Brief Summary ----------------- This clinical trial aims to investigate the efficacy of Calcipotriol ointment combined with 5-FU cream in Organ Transplant Recipients (OTRs) to determine if it ...	ctgov
Vascular Post Market Review Study Overview ================= Brief Summary ----------------- The primary objective of this study is to confirm that properties of CardioCel provide operative benefit to surgeons when compared to Dacron, CorMatrix, and all other bovine pericardium not treated with proprietary ADAPT engin...	ctgov
Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease Study Overview ================= Brief Summary ----------------- By doing this study, researchers will examine the safety and tolerability of R-pramipexole in participants with Alzheimer's disease. This study will also examine the body and brain's resp...	ctgov
Impact of an Educational Tool on Quality of Life and Anxiety in Parents of Children With Nut Allergy Study Overview ================= Brief Summary ----------------- The number of young children with food allergy, in particular with nut allergy, is increasing worldwide. A diagnosis of nut allergy can cause much anxiet...	ctgov
A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A) Study Overview ================= Brief Summary ----------------- This is a phase I/II multicenter, open-label umbrella platform study that will evaluate the safety ...	ctgov
Sympathetic Activity in Patients With End-stage Renal Disease on Peritoneal Dialysis Study Overview ================= Brief Summary ----------------- Hypothesis: Patients starting peritoneal dialysis with a glucose-based regimen have high sympathetic activity in response to an increase in leptin and insulin. Convertin...	ctgov
To Evaluate Efficacy and Safety of Parsaclisib Plus Either Rituximab or Obinutuzumab in R/R Follicular Lymphoma (FL) and Marginal Zone Lymphoma (MZL) (CITADEL-302) Study Overview ================= Brief Summary ----------------- This is a Phase 3, double-blind, randomized, placebo-controlled, multicenter study of pars...	ctgov
Multicenter Retrospective Observatory of Patients With Acute Myeloid Leukemia to Core Binding Factor Study Overview ================= Brief Summary ----------------- Acute Core Binding Factor leukemias represent a specific category of acute myeloid leukemias that share prognostic factors, a specific mutational profile...	ctgov
Preparing for Eating Disorders Treatment Through Compassionate Letter-Writing Study Overview ================= Brief Summary ----------------- Compassion-focused therapy (CFT) seeks to lower shame and help people develop compassion for personal distress and shortcomings. There is increasing evidence to support the ben...	ctgov
Preoperative Exercise Training for Pelvic Floor in Urinary Incontinence Post RALP Study Overview ================= Brief Summary ----------------- The aim of the study is to investigate how posology and typology of preoperative strengthening training of Pelvic Floor Muscle before RALP surgery can affect the postoperat...	ctgov
Cardiac Function and Morphology Evaluated by Magnetic Resonance Imaging in Growth Hormone Deficiency and Acromegaly Study Overview ================= Brief Summary ----------------- To test the hypothesis that both lack and excess of growth hormone (GH) is associated with cardiac abnormalities. Cardiac function and mor...	ctgov
Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats Study Overview ================= Brief Summary ----------------- The aim of the study is to show non-inferiority of an echinacea/sage spray compared to a chl...	ctgov
DNA Adductomics for Colorectal Cancer Investigation Study Overview ================= Brief Summary ----------------- This project seeks to identify DNA-adducts in colon tissue from different groups of patients with CRC scheduled for complete or partial colon resections. Other patients scheduled for resection of the co...	ctgov
Study to Evaluate the Safety and Efficacy of a Proprietary Joint Health Dietary Supplement in Subjects With Joint and Connective Tissue Pain Study Overview ================= Brief Summary ----------------- This study is designed to evaluate the effectiveness of a proprietary nutritional supplement that contains Krill ...	ctgov
Naldebain® Extended-release Injection After Cesarean Section in Pain Management Study Overview ================= Brief Summary ----------------- Cesarean section is one of the surgeries most commonly leading to postoperative severe acute pain. It was reported that the mean worst pain intensity reached to 6.14 one day ...	ctgov
A Cytomegalovirus-Directed Vaccine (CMV-alphaDC1) for Preventing Cytomegalovirus Infection or Reactivation in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation Study Overview ================= Brief Summary ----------------- This phase Ib trial evaluates the safety and most effective dose of a cyt...	ctgov
A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014) Study Overview ================= Brief Summary ----------------- An investigational study to determine the safety/tolerability, and efficacy of a notch signaling pathway inhibitor in patients with metastatic or locally advanced br...	ctgov
Auditory Training and Hearing Aid Satisfaction Study Overview ================= Brief Summary ----------------- Although hearing aids are the most common treatment for hearing loss, and have the potential to help seniors stay active and productive, almost 50% of them who receive hearing aids rarely if ever use them, a...	ctgov
PEGI to Improve Shared Decision-Making for Breast Reconstruction Study Overview ================= Brief Summary ----------------- The purpose of this study is to determine the effectiveness of a pre-consultation decision support workshop for breast reconstruction after breast cancer, in facilitating the decision-makin...	ctgov
A Trauma-Informed Approach for Positive Youth Development for Montana Students Study Overview ================= Brief Summary ----------------- Given the prevalence of suicide and mental health issues in rural Montana, this project is intended to help mitigate stressors that may contribute to poor behavioral and menta...	ctgov
Automated Breast Ultrasound Screening Study Overview ================= Brief Summary ----------------- Women with dense breasts (BIRADS 3 or 4) with a BIRADS category 1 or 2 mammogram are asked to participate in a automated volume breast ultrasound scanner. The study evaluates prospectively the changes in recall rate,...	ctgov
Tow Techniques of Adductor Canal Block for Analgesia After Total Knee Replacement Study Overview ================= Brief Summary ----------------- This study compares the tow technique of continues adductor canal block for total knee replacement surgery. Half participants will receive catheterization at the entrance o...	ctgov
A Study Assessing 13-valent Pneumococcal Conjugate Vaccine in Healthy Chinese Subjects Study Overview ================= Brief Summary ----------------- This study will assess the safety and tolerability of a single dose of 13-valent Pneumococcal Conjugate Vaccine for approximately 1 month after vaccination sequentiall...	ctgov
Therapeutic Drug Monitoring of Ixekizumab in Psoriasis Patients Study Overview ================= Brief Summary ----------------- Biologics, such as ixekizumab, are currently the most effective treatment option for patients with moderate-to-severe psoriasis. But they are costly for health care systems and prescribed ac...	ctgov
The Effect of Cognitive Function as Measured by Repeated Cognitive Measures After 12 Weeks Treatment With Donepezil Study Overview ================= Brief Summary ----------------- The purpose of this study is to determine if there is improvement or measurable change in cognition after only one month of treatment with...	ctgov
Interactive Gentle Yoga in Improving Quality of Life in Patients With Stage I-III Breast Cancer Undergoing Radiation Therapy Study Overview ================= Brief Summary ----------------- This pilot clinical trial studies interactive gentle yoga in improving quality of life in patients with stage I-III breast cancer...	ctgov
Comparison of Two Silicone Hydrogel Toric Contact Lenses Study Overview ================= Brief Summary ----------------- The purpose of this research study is to compare the performance of two different types of Alcon soft toric study contact lenses to obtain information on study lens orientation. Official Title ---...	ctgov
Identification of Biomarkers for Obstructive Sleep Apnoea Syndrome Study Overview ================= Brief Summary ----------------- Untreated Obstructive Sleep Apnea Syndrome (OSAS) has long-term complications, namely metabolic imbalances (obesity, dislipidemia, type 2 diabetes mellitus). Until now, no molecular marke...	ctgov
Bendamustine and Bortezomib Combination Therapy in Indolent Non-Hodgkin's Lymphoma(NHL) Study Overview ================= Brief Summary ----------------- The purpose of this study is to determine whether the combination of bendamustine and bortezomib in patients with indolent Non-Hodgkin's Lymphoma or Chronic Lymphocyt...	ctgov
Preoperative Lymph Node Staging With EBUS-TBNA in Clinical N0 Non Small-cell Lung Cancer Study Overview ================= Brief Summary ----------------- The introduction of modern staging systems has increased the detection of small peripheral lung cancers at an early stage [1]. Stage I non-small-cell lung cancers (N...	ctgov
Microendoscopic Discectomy Vs Transforaminal Endoscopic Lumbar Discectomy Vs Open Discectomy Study Overview ================= Brief Summary ----------------- In our study, a multicenter randomized controlled，single blind trial will be performed to evaluate the effectiveness and safety of these three procedures for the...	ctgov
Antiresorptive Effect of Treatment With Risedronate and Vitamin D in Postmenopausal Patients Study Overview ================= Brief Summary ----------------- Osteoporosis is defined as a systemic disease of bone mineralization, characterized by a decrease in bone mineral density that causes bone fragility and increase...	ctgov
Effect of Anesthetics on Oxygenation and Microcirculation During One-lung Ventilation Study Overview ================= Brief Summary ----------------- One-lung ventilation during thoracic surgery may affect systemic oxygenation and peripheral microcirculation by hypoxic pulmonary vasoconstriction. Both intravenous and...	ctgov
Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome Study Overview ================= Brief Summary ----------------- Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline versus dexmedetomidine...	ctgov
Pharmacokinetics of Oral Capsule in Healthy Japanese vs. Caucasian Subjects Study Overview ================= Brief Summary ----------------- This is a single and multiple dose, parallel group study to assess safety and pharmacokinetics of oral HTL0018318 in healthy Japanese and Caucasian subjects. Detailed Descriptio...	ctgov
The Influence of Acute Myocardial Infarction Checklist on the Door-to-Balloon Time Study Overview ================= Brief Summary ----------------- This study was designed to investigate the influence of the acute myocardial infarction checklist on the door-to-balloon time in patients suffering from acute STEMI at Far...	ctgov

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