Split (1)

train · 8.69k rows

Entrez ID int64 47 103M ⌀	Gene symbol stringclasses 866 values	Gene name stringclasses 866 values	Cancer Cell stringclasses 2 values	Type of senescence stringclasses 4 values	Senescence Effect stringclasses 3 values	Reference int64 1.56M 33.5M ⌀
22,848	AAK1	AP2 associated kinase 1	No	Unclear	Induces	26,583,757
5,243	ABCB1	ATP binding cassette subfamily B member 1	Yes	Stress-induced	Induces	10,825,123
368	ABCC6	ATP binding cassette subfamily C member 6	Yes	Unclear	Inhibits	28,536,638
51,225	ABI3	ABI family member 3	Yes	Oncogene-induced	Induces	21,223,585
25,890	ABI3BP	ABI family member 3 binding protein	Yes	Unclear	Induces	18,559,958
340,485	ACER2	alkaline ceramidase 2	Yes	Replicative	Inhibits	29,229,990
340,485	ACER2	alkaline ceramidase 2	Yes	Stress-induced	Inhibits	29,229,990
2,532	ACKR1	atypical chemokine receptor 1 (Duffy blood group)	No	Stress-induced	Induces	17,955,335
47	ACLY	ATP citrate lyase	No	Unclear	Inhibits	25,367,309
203,054	ADCK5	aarF domain containing kinase 5	No	Unclear	Induces	26,583,757
27,161	AGO2	argonaute RISC catalytic component 2	No	Oncogene-induced	Inhibits	25,175,024
10,551	AGR2	anterior gradient 2, protein disulphide isomerase family member	Yes	Oncogene-induced	Inhibits	22,467,239
183	AGT	angiotensinogen	No	Stress-induced	Induces	16,908,765
196	AHR	aryl hydrocarbon receptor	No	Stress-induced	Induces	15,111,621
8,852	AKAP4	A-kinase anchoring protein 4	Yes	Unclear	Inhibits	26,590,805
231	AKR1B1	aldo-keto reductase family 1 member B	Yes	Stress-induced	Inhibits	21,182,935
207	AKT1	AKT serine/threonine kinase 1	No	Oncogene-induced	Induces	17,045,205
84,335	AKT1S1	AKT1 substrate 1	Yes	Oncogene-induced	Inhibits	24,704,832
10,000	AKT3	AKT serine/threonine kinase 3	Yes	Stress-induced	Inhibits	26,972,278
64,400	AKTIP	AKT interacting protein	No	Replicative	Inhibits	27,512,140
217	ALDH2	aldehyde dehydrogenase 2 family member	No	Stress-induced	Inhibits	30,538,807
226	ALDOA	aldolase, fructose-bisphosphate A	Yes	Oncogene-induced	Inhibits	28,806,777
221,120	ALKBH3	alkB homolog 3, alpha-ketoglutarate dependent dioxygenase	Yes	Unclear	Inhibits	21,285,982
247	ALOX15B	arachidonate 15-lipoxygenase type B	No	Unclear	Induces	17,164,141
64,682	ANAPC1	anaphase promoting complex subunit 1	No	Unclear	Inhibits	25,255,445
54,443	ANLN	anillin actin binding protein	Yes	Unclear	Inhibits	27,863,473
308	ANXA5	annexin A5	No	Replicative	Inhibits	22,728,018
308	ANXA5	annexin A5	No	Stress-induced	Inhibits	22,728,018
328	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1	No	Replicative	Inhibits	29,750,271
367	AR	androgen receptor	No	Unclear	Induces	24,244,503
375	ARF1	ADP ribosylation factor 1	No	Oncogene-induced	Induces	29,420,297
384	ARG2	arginase 2	No	Unclear	Induces	23,832,324
384	ARG2	arginase 2	No	Unclear	Induces	22,928,666
8,289	ARID1A	AT-rich interaction domain 1A	No	Oncogene-induced	Induces	28,942,143
57,492	ARID1B	AT-rich interaction domain 1B	No	Oncogene-induced	Induces	27,737,960
1,820	ARID3A	AT-rich interaction domain 3A	No	Oncogene-induced	Inhibits	11,812,999
51,742	ARID4B	AT-rich interaction domain 4B	Yes	Oncogene-induced	Induces	16,479,010
10,095	ARPC1B	actin related protein 2/3 complex subunit 1B	Yes	Unclear	Induces	21,628,992
408	ARRB1	arrestin beta 1	Yes	Unclear	Induces	31,204,931
427	ASAH1	N-acylsphingosine amidohydrolase 1	Yes	Unclear	Inhibits	28,785,021
25,842	ASF1A	anti-silencing function 1A histone chaperone	No	Replicative	Induces	15,621,527
25,842	ASF1A	anti-silencing function 1A histone chaperone	No	Oncogene-induced	Induces	15,621,527
444	ASPH	aspartate beta-hydroxylase	Yes	Unclear	Inhibits	26,683,595
55,252	ASXL2	ASXL transcriptional regulator 2	No	Unclear	Induces	26,416,890
467	ATF3	activating transcription factor 3	Yes	Stress-induced	Inhibits	25,046,976
22,926	ATF6	activating transcription factor 6	No	Replicative	Induces	28,803,844
22,926	ATF6	activating transcription factor 6	No	Stress-induced	Induces	28,803,844
22,926	ATF6	activating transcription factor 6	No	Oncogene-induced	Induces	28,803,844
22,926	ATF6	activating transcription factor 6	No	Replicative	Induces	30,260,700
22,926	ATF6	activating transcription factor 6	No	Stress-induced	Induces	30,260,700
22,926	ATF6	activating transcription factor 6	No	Oncogene-induced	Induces	30,260,700
55,729	ATF7IP	activating transcription factor 7 interacting protein	No	Stress-induced	Inhibits	23,935,871
83,734	ATG10	autophagy related 10	Yes	Unclear	Induces	23,451,179
9,140	ATG12	autophagy related 12	No	Unclear	Inhibits	21,858,089
55,054	ATG16L1	autophagy related 16 like 1	Yes	Unclear	Unclear	22,684,298
84,971	ATG4D	autophagy related 4D cysteine peptidase	No	Unclear	Inhibits	30,352,807
9,474	ATG5	autophagy related 5	No	Oncogene-induced	Inhibits	19,279,323
10,533	ATG7	autophagy related 7	No	Oncogene-induced	Inhibits	19,279,323
472	ATM	ATM serine/threonine kinase	No	Replicative	Inhibits	9,312,059
23,545	ATP6V0A2	ATPase H+ transporting V0 subunit a2	No	Unclear	Inhibits	26,611,489
527	ATP6V0C	ATPase H+ transporting V0 subunit c	No	Unclear	Inhibits	30,352,807
545	ATR	ATR serine/threonine kinase	Yes	Oncogene-induced	Induces	18,245,444
51,374	ATRAID	all-trans retinoic acid induced differentiation factor	Yes	Unclear	Induces	26,934,949
546	ATRX	ATRX chromatin remodeler	Yes	Oncogene-induced	Induces	28,855,512
546	ATRX	ATRX chromatin remodeler	Yes	Stress-induced	Induces	28,855,512
25,814	ATXN10	ataxin 10	No	Unclear	Induces	21,740,549
6,790	AURKA	aurora kinase A	Yes	Unclear	Inhibits	23,324,396
9,212	AURKB	aurora kinase B	No	Unclear	Inhibits	22,024,481
558	AXL	AXL receptor tyrosine kinase	No	Unclear	Induces	26,583,757
9,531	BAG3	BAG cochaperone 3	Yes	Unclear	Inhibits	25,412,315
8,314	BAP1	BRCA1 associated protein 1	No	Unclear	Induces	26,416,890
11,177	BAZ1A	bromodomain adjacent to zinc finger domain 1A	Yes	Unclear	Inhibits	31,085,244
64,919	BCL11B	BAF chromatin remodeling complex subunit BCL11B	Yes	Unclear	Inhibits	26,096,706
596	BCL2	BCL2 apoptosis regulator	No	Oncogene-induced	Induces	12,670,482
598	BCL2L1	BCL2 like 1	Yes	Oncogene-induced	Inhibits	28,948,203
599	BCL2L2	BCL2 like 2	Yes	Oncogene-induced	Induces	30,318,121
602	BCL3	BCL3 transcription coactivator	No	Unclear	Inhibits	25,255,445
604	BCL6	BCL6 transcription repressor	No	Replicative	Inhibits	11,914,273
9,774	BCLAF1	BCL2 associated transcription factor 1	Yes	Stress-induced	Induces	26,794,446
8,678	BECN1	beclin 1	Yes	Unclear	Inhibits	29,991,800
8,553	BHLHE40	basic helix-loop-helix family member e40	Yes	Replicative	Induces	18,025,081
8,553	BHLHE40	basic helix-loop-helix family member e40	Yes	Stress-induced	Induces	18,025,081
8,553	BHLHE40	basic helix-loop-helix family member e40	Yes	Replicative	Induces	22,844,531
8,553	BHLHE40	basic helix-loop-helix family member e40	Yes	Stress-induced	Induces	22,844,531
274	BIN1	bridging integrator 1	No	Oncogene-induced	Induces	18,267,069
332	BIRC5	baculoviral IAP repeat containing 5	Yes	Oncogene-induced	Inhibits	27,531,889
640	BLK	BLK proto-oncogene, Src family tyrosine kinase	No	Unclear	Induces	26,583,757
644	BLVRA	biliverdin reductase A	No	Stress-induced	Inhibits	21,099,244
648	BMI1	BMI1 proto-oncogene, polycomb ring finger	No	Replicative	Inhibits	12,482,990
652	BMP4	bone morphogenetic protein 4	Yes	Replicative	Induces	19,269,967
652	BMP4	bone morphogenetic protein 4	Yes	Stress-induced	Induces	19,269,967
659	BMPR2	bone morphogenetic protein receptor type 2	Yes	Replicative	Induces	27,696,331
9,790	BMS1	BMS1 ribosome biogenesis factor	Yes	Replicative	Inhibits	25,732,822
9,790	BMS1	BMS1 ribosome biogenesis factor	Yes	Oncogene-induced	Inhibits	25,732,822
665	BNIP3L	BCL2 interacting protein 3 like	No	Oncogene-induced	Induces	18,267,069
673	BRAF	B-Raf proto-oncogene, serine/threonine kinase	No	Oncogene-induced	Induces	16,079,850
672	BRCA1	BRCA1 DNA repair associated	Yes	Stress-induced	Inhibits	19,372,557
23,476	BRD4	bromodomain containing 4	Yes	Unclear	Inhibits	29,434,197
29,117	BRD7	bromodomain containing 7	No	Replicative	Induces	20,660,729
83,990	BRIP1	BRCA1 interacting helicase 1	No	Oncogene-induced	Inhibits	22,137,763

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