Split (1)

train · 8.69k rows

Entrez ID int64 47 103M ⌀	Gene symbol stringclasses 866 values	Gene name stringclasses 866 values	Cancer Cell stringclasses 2 values	Type of senescence stringclasses 4 values	Senescence Effect stringclasses 3 values	Reference int64 1.56M 33.5M ⌀
23,564	DDAH2	dimethylarginine dimethylaminohydrolase 2	No	Unclear	Inhibits	24,764,313
1,642	DDB1	damage specific DNA binding protein 1	Yes	Oncogene-induced	Inhibits	28,806,777
1,643	DDB2	damage specific DNA binding protein 2	No	Oncogene-induced	Induces	20,351,176
54,541	DDIT4	DNA damage inducible transcript 4	No	Replicative	Inhibits	22,627,671
7,913	DEK	DEK proto-oncogene	No	Replicative	Inhibits	16,254,365
64,798	DEPTOR	DEP domain containing MTOR interacting protein	Yes	Unclear	Inhibits	25,568,666
54,487	DGCR8	DGCR8 microprocessor complex subunit	No	Unclear	Inhibits	23,773,483
1,718	DHCR24	24-dehydrocholesterol reductase	No	Oncogene-induced	Induces	15,577,914
10,202	DHRS2	dehydrogenase/reductase 2	Yes	Unclear	Induces	29,632,240
1,660	DHX9	DExH-box helicase 9	No	Replicative	Inhibits	24,990,949
23,405	DICER1	dicer 1, ribonuclease III	No	Stress-induced	Inhibits	26,990,999
11,083	DIDO1	death inducer-obliterator 1	No	Unclear	Inhibits	26,611,489
9,077	DIRAS3	DIRAS family GTPase 3	No	Unclear	Inhibits	28,316,325
1,736	DKC1	dyskerin pseudouridine synthase 1	Yes	Replicative	Inhibits	25,732,822
1,736	DKC1	dyskerin pseudouridine synthase 1	Yes	Oncogene-induced	Inhibits	25,732,822
10,395	DLC1	DLC1 Rho GTPase activating protein	Yes	Oncogene-induced	Induces	23,853,104
9,988	DMTF1	cyclin D binding myb like transcription factor 1	No	Oncogene-induced	Induces	18,267,069
1,786	DNMT1	DNA methyltransferase 1	No	Unclear	Inhibits	21,572,997
1,788	DNMT3A	DNA methyltransferase 3 alpha	Yes	Stress-induced	Inhibits	20,473,858
1,789	DNMT3B	DNA methyltransferase 3 beta	No	Unclear	Inhibits	21,572,997
84,444	DOT1L	DOT1 like histone lysine methyltransferase	Yes	Unclear	Inhibits	22,190,683
1,803	DPP4	dipeptidyl peptidase 4	No	Oncogene-induced	Induces	29,481,642
84,661	DPY30	dpy-30 histone methyltransferase complex regulatory subunit	No	Unclear	Inhibits	23,872,946
51,514	DTL	denticleless E3 ubiquitin protein ligase homolog	Yes	Unclear	Inhibits	29,606,879
1,843	DUSP1	dual specificity phosphatase 1	Yes	Oncogene-induced	Induces	30,536,303
80,824	DUSP16	dual specificity phosphatase 16	Yes	Unclear	Inhibits	26,381,291
63,904	DUSP21	dual specificity phosphatase 21	Yes	Unclear	Inhibits	23,929,653
1,845	DUSP3	dual specificity phosphatase 3	Yes	Unclear	Inhibits	16,604,064
1,848	DUSP6	dual specificity phosphatase 6	Yes	Oncogene-induced	Inhibits	25,499,223
1,859	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	Yes	Oncogene-induced	Induces	21,498,570
1,869	E2F1	E2F transcription factor 1	No	Unclear	Induces	10,594,030
1,871	E2F3	E2F transcription factor 3	Yes	Unclear	Inhibits	22,354,972
144,455	E2F7	E2F transcription factor 7	No	Oncogene-induced	Induces	22,802,529
1,894	ECT2	epithelial cell transforming 2	Yes	Oncogene-induced	Inhibits	28,806,777
9,521	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	No	Unclear	Induces	25,465,621
1,956	EGFR	epidermal growth factor receptor	Yes	Unclear	Inhibits	25,504,754
54,583	EGLN1	egl-9 family hypoxia inducible factor 1	Yes	Replicative	Induces	16,161,047
1,959	EGR2	early growth response 2	No	Unclear	Induces	33,547,862
26,298	EHF	ETS homologous factor	No	Unclear	Induces	17,627,613
10,919	EHMT2	euchromatic histone lysine methyltransferase 2	Yes	Unclear	Inhibits	25,595,900
493,861	EID3	EP300 interacting inhibitor of differentiation 3	Yes	Stress-induced	Induces	30,114,644
5,610	EIF2AK2	eukaryotic translation initiation factor 2 alpha kinase 2	No	Stress-induced	Induces	29,906,232
9,451	EIF2AK3	eukaryotic translation initiation factor 2 alpha kinase 3	Yes	Unclear	Inhibits	22,548,801
1,977	EIF4E	eukaryotic translation initiation factor 4E	Yes	Oncogene-induced	Unclear	21,399,233
1,978	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	No	Oncogene-induced	Inhibits	19,878,875
1,982	EIF4G2	eukaryotic translation initiation factor 4 gamma 2	Yes	Unclear	Inhibits	24,497,838
1,994	ELAVL1	ELAV like RNA binding protein 1	Yes	Replicative	Inhibits	29,584,879
6,924	ELOA	elongin A	No	Unclear	Inhibits	32,264,951
2,021	ENDOG	endonuclease G	No	Unclear	Inhibits	20,211,237
2,022	ENG	endoglin	Yes	Unclear	Induces	27,067,789
2,023	ENO1	enolase 1	No	Oncogene-induced	Inhibits	18,852,884
57,089	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7	No	Oncogene-induced	Induces	27,737,960
2,033	EP300	E1A binding protein p300	No	Replicative	Induces	30,773,298
2,033	EP300	E1A binding protein p300	No	Oncogene-induced	Induces	30,773,298
2,034	EPAS1	endothelial PAS domain protein 1	Yes	Replicative	Inhibits	26,057,707
2,034	EPAS1	endothelial PAS domain protein 1	Yes	Stress-induced	Inhibits	26,057,707
2,042	EPHA3	EPH receptor A3	Yes	Unclear	Inhibits	23,324,396
2,044	EPHA5	EPH receptor A5	Yes	Stress-induced	Inhibits	25,623,065
2,057	EPOR	erythropoietin receptor	Yes	Stress-induced	Inhibits	25,544,764
2,064	ERBB2	erb-b2 receptor tyrosine kinase 2	Yes	Oncogene-induced	Induces	15,705,882
2,067	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit	No	Unclear	Inhibits	24,964,749
54,206	ERRFI1	ERBB receptor feedback inhibitor 1	No	Unclear	Induces	24,815,188
30,816	ERVW-1	endogenous retrovirus group W member 1, envelope	No	Oncogene-induced	Induces	24,186,980
9,700	ESPL1	extra spindle pole bodies like 1, separase	Yes	Oncogene-induced	Inhibits	28,806,777
2,099	ESR1	estrogen receptor 1	No	Oncogene-induced	Inhibits	27,259,243
2,103	ESRRB	estrogen related receptor beta	Yes	Stress-induced	Induces	25,496,115
2,113	ETS1	ETS proto-oncogene 1, transcription factor	No	Oncogene-induced	Induces	11,234,019
2,114	ETS2	ETS proto-oncogene 2, transcription factor	No	Oncogene-induced	Induces	11,234,019
2,120	ETV6	ETS variant transcription factor 6	No	Unclear	Induces	30,088,951
2,130	EWSR1	EWS RNA binding protein 1	No	Unclear	Induces	21,030,557
2,146	EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit	Yes	Stress-induced	Inhibits	24,588,771
2,177	FANCD2	FA complementation group D2	No	Stress-induced	Induces	21,995,812
2,194	FASN	fatty acid synthase	No	Oncogene-induced	Induces	30,962,418
10,922	FASTK	Fas activated serine/threonine kinase	No	Unclear	Induces	26,583,757
26,263	FBXO22	F-box protein 22	Yes	Stress-induced	Induces	26,868,148
79,791	FBXO31	F-box protein 31	Yes	Unclear	Induces	16,357,137
26,272	FBXO4	F-box protein 4	Yes	Unclear	Induces	29,142,209
26,271	FBXO5	F-box protein 5	Yes	Oncogene-induced	Inhibits	17,875,940
23,291	FBXW11	F-box and WD repeat domain containing 11	Yes	Unclear	Inhibits	31,406,304
2,224	FDPS	farnesyl diphosphate synthase	Yes	Stress-induced	Inhibits	29,030,460
55,612	FERMT1	FERM domain containing kindlin 1	No	Unclear	Inhibits	23,278,235
10,979	FERMT2	FERM domain containing kindlin 2	Yes	Unclear	Inhibits	31,308,359
26,291	FGF21	fibroblast growth factor 21	No	Replicative	Inhibits	31,178,962
26,291	FGF21	fibroblast growth factor 21	No	Stress-induced	Inhibits	31,178,962
2,260	FGFR1	fibroblast growth factor receptor 1	Yes	Stress-induced	Induces	26,250,908
2,263	FGFR2	fibroblast growth factor receptor 2	No	Oncogene-induced	Unclear	19,403,560
2,261	FGFR3	fibroblast growth factor receptor 3	Yes	Oncogene-induced	Induces	23,902,722
51,024	FIS1	fission, mitochondrial 1	Yes	Unclear	Inhibits	17,545,159
2,321	FLT1	fms related receptor tyrosine kinase 1	No	Unclear	Inhibits	18,583,712
100,529,261	FNTB	CHURC1-FNTB readthrough	Yes	Stress-induced	Inhibits	29,030,460
2,353	FOS	Fos proto-oncogene, AP-1 transcription factor subunit	No	Unclear	Inhibits	1,560,044
3,169	FOXA1	forkhead box A1	Yes	Unclear	Induces	27,349,269
2,297	FOXD1	forkhead box D1	No	Replicative	Unclear	30,933,975
2,305	FOXM1	forkhead box M1	Yes	Unclear	Inhibits	25,071,344
2,308	FOXO1	forkhead box O1	No	Unclear	Induces	30,088,951
2,309	FOXO3	forkhead box O3	No	Unclear	Inhibits	15,741,276
4,303	FOXO4	forkhead box O4	Yes	Oncogene-induced	Induces	20,959,475
27,086	FOXP1	forkhead box P1	No	Replicative	Inhibits	28,240,601
50,943	FOXP3	forkhead box P3	Yes	Oncogene-induced	Induces	27,238,838
94,234	FOXQ1	forkhead box Q1	No	Unclear	Inhibits	29,500,491

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