REFERENCE_ID int64 273 7.3M | TITLE stringlengths 4 390 | AUTHORS stringlengths 5 1.43k ⌀ | YEAR int64 1.85k 2.02k ⌀ | ABSTRACT stringlengths 1 18.4k ⌀ | CITED int64 0 1 |
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741,990 | Climate change and its effects on terrestrial insects and herbivory patterns | Cornelissen, T | 2,011 | Climate change and extreme weather events affect plants and animals and the direct impact of anthropogenic climate change has been documented extensively over the past years. In this review, I address the main consequences of elevated CO2 and O3 concentrations, elevated temperature and changes in rainfall patterns on t... | 1 |
732,548 | Short-term effect of fine particulate matter (PM2.5) and ozone on daily mortality in Lisbon, Portugal | Garrett, P; Casimiro, E | 2,011 | Introduction
Urban ambient air pollution exposures continue to be a global public health concern. Although air quality targets are often exceeded in Lisbon, the largest city in Portugal, there is currently no study that has assessed the quantitative impact of these pollutants on daily mortality.
Materials and method... | 0 |
749,414 | Air pollution and airway disease | Kelly, FJ; Fussell, JC | 2,011 | Epidemiological and toxicological research continues to support a link between urban air pollution and an increased incidence and/or severity of airway disease. Detrimental effects of ozone (O(3) ), nitrogen dioxide (NO(2) ) and particulate matter (PM), as well as traffic-related pollution as a whole, on respiratory sy... | 0 |
749,260 | AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice | Hulo, S; Tiesset, H; Lancel, S; Edme, JL; Viollet, B; Sobaszek, A; Neviere, R | 2,011 | ABSTRACT: BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major prooxidant pro... | 0 |
749,435 | Isoprostanes and asthma | Voynow, JA; Kummarapurugu, A | 2,011 | Isoprostanes are prostaglandin (PG)-like compounds generated in vivo following oxidative stress by non-enzymatic peroxidation of polyunsaturated fatty acids, including arachidonic acid. They are named based on their prostane ring structure and by the localization of hydroxyl groups on the carbon side chain; these struc... | 0 |
836,740 | Nitrogen Balance in the Ecosystem of the Cystic Fibrosis Lung | Marozkina, NV; Gaston, B | 2,011 | null | 0 |
749,413 | Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone | Esther, CR; Peden, DB; Alexis, NE; Hernandez, ML | 2,011 | Context: Ozone exposure triggers airway inflammatory responses that may be influenced by biologically active purine metabolites. Objective: To examine the relationships between airway purine metabolites and established inflammatory markers of ozone exposure, and to determine if these relationships are altered in indivi... | 1 |
732,556 | Associations between ozone and morbidity using the spatial synoptic classification system | Hanna, AF; Yeatts, KB; Xiu, A; Zhu, Z; Smith, RL; Davis, NN; Talgo, KD; Arora, G; Robinson, PJ; Meng, Q; Pinto, JP | 2,011 | Background: Synoptic circulation patterns (large-scale tropospheric motion systems) affect air pollution and, potentially, air-pollution-morbidity associations. We evaluated the effect of synoptic circulation patterns (air masses) on the association between ozone and hospital admissions for asthma and myocardial infarc... | 0 |
783,785 | Elevated carbon dioxide and/or ozone concentrations induce hormonal changes in Pinus tabulaeformis | Li, XM; Zhang, LH; Ma, LJ; Li, YY | 2,011 | We investigated endogenous plant hormones and needle growth in Pinus tabulaeformis plants grown in open-top chambers and exposed to ambient or elevated concentrations of carbon dioxide (CO(2)) and/or ozone (O(3)). Exposure to elevated CO(2) for 100 days significantly increased the change in fresh needle weight, indole-... | 0 |
749,274 | GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozone | Wu, W; Doreswamy, V; Diaz-Sanchez, D; Samet, JM; Kesic, M; Dailey, L; Zhang, W; Jaspers, I; Peden, DB | 2,011 | Exposure to the major air pollutant ozone can aggravate asthma and other lung diseases. Our recent study in human volunteers has shown that the glutathione S-transferase Mu 1 (GSTM1)-null genotype is associated with increased airway neutrophilic inflammation induced by inhaled ozone. The aim of this study was to examin... | 1 |
749,436 | Emerging pathways in asthma: Innate and adaptive interactions | Lin, KW; Li, J; Finn, PW | 2,011 | BACKGROUND: Allergic asthma is a complex and chronic airway inflammatory disorder, and the prevalence of asthma has increased. Adaptive antigen-dependent immunity is a classical pathway of asthmatic pathology. Recent studies have focused on innate antigen-independent immunity in asthma. SCOPE OF REVIEW: This review dis... | 0 |
677,550 | Ozone biomonitoring program | null | 2,011 | In 1994, the Forest Inventory and Analysis (FIA: http://fia.fs.fed.us) and Forest Health Monitoring (FHM: http://fhm.fs.fed.us) programs of the USDA Forest Service implemented a national ozone biomonitoring program to demonstrate their commitment to sustainable forest management and The Montreal Process (http://www.mpc... | 1 |
783,763 | Soil microbial responses to elevated CO2 and O3 in a nitrogen-aggrading agroecosystem | Cheng, L; Booker, FL; Burkey, KO; Tu, C; Shew, HD; Rufty, TW; Fiscus, EL; Deforest, JL; Hu, S | 2,011 | Climate change factors such as elevated atmospheric carbon dioxide (CO?) and ozone (O?) can exert significant impacts on soil microbes and the ecosystem level processes they mediate. However, the underlying mechanisms by which soil microbes respond to these environmental changes remain poorly understood. The prevailing... | 0 |
785,513 | Influence of tropospheric ozone control on exposure to ultraviolet radiation at the surface | Madronich, S; Wagner, M; Groth, P | 2,011 | Improving air quality by reducing ambient ozone (O(3)) will likely lower O(3) concentrations throughout the troposphere and increase the transmission of solar ultraviolet (UV) radiation to the surface. The changes in surface UV radiation between two control scenarios (nominally 84 and 70 ppb O(3) for summer 2020) in th... | 1 |
783,819 | The Chemistry of Atmosphere-Forest Exchange (CAFE) Model ? Part 1: Model description and characterization | Wolfe, GM; Thornton, JA | 2,011 | We present the Chemistry of Atmosphere-Forest Exchange (CAFE) model, a vertically-resolved 1-D chemical transport model designed to probe the details of near-surface reactive gas exchange. CAFE integrates all key processes, including turbulent diffusion, emission, deposition and chemistry, throughout the forest canopy ... | 0 |
782,681 | Atmospheric chemistry in stereo: A new look at secondary organic aerosols from isoprene | Noziere, B; Gonzalez, NJD; Borg-Karlson, AK; Pei, Y; Redeby, JP; Krejci, R; Dommen, J; Prevot, ASH; Anthonsen, T | 2,011 | Isoprene, a compound emitted by vegetation, could be a major contributor to secondary organic aerosols (SOA) in the atmosphere. The main evidence for this contribution were the 2-methylbutane-1,2,3,4-tetraols, or 2-methyltetrols (2-methylerythritol and 2-methylthreitol) present in ambient aerosols. In this work, the fo... | 1 |
696,635 | Subalpine grassland carbon dioxide fluxes indicate substantial carbon losses under increased nitrogen deposition, but not at elevated ozone concentration | Volk, M; Obrist, D; Novak, K; Giger, R; Bassin, S; Fuhrer, J | 2,011 | Ozone (O3) and nitrogen (N) deposition affect plant carbon (C) dynamics and may change ecosystem C-sink/-source properties. We studied effects of increased background [O3] (up to [ambient] ? 2) and increased N deposition (up to +50 kg ha?1 a?1) on mature, subalpine grassland during the third treatment year. During 10 d... | 1 |
202,800 | The use of alternative pollutant metrics in time-series studies of ambient air pollution and respiratory emergency department visits | Darrow, LA; Klein, M; Sarnat, JA; Mulholland, JA; Strickland, MJ; Sarnat, SE; Russell, AG; Tolbert, PE | 2,011 | Various temporal metrics of daily pollution levels have been used to examine the relationships between air pollutants and acute health outcomes. However, daily metrics of the same pollutant have rarely been systematically compared within a study. In this analysis, we describe the variability of effect estimates attribu... | 1 |
1,533,560 | Air quality trends in Europe over the past decade: a first multi- model assessment | Colette, A; Granier, C; Hodnebrog, O; Jakobs, H; Maurizi, A; Nyiri, A; Bessagnet, B; D'Angiola, A; D'Isidoro, M; Gauss, M; Meleux, F; Memmesheimer, M; Mieville, A; Rouil, L; Russo, F; Solberg, S; Stordal, F; Tampieri, F | 2,011 | We discuss the capability of current state-of-the-art chemistry and transport models to reproduce air quality trends and interannual variability. Documenting these strengths and weaknesses on the basis of historical simulations is essential before the models are used to investigate future air quality projections. To ac... | 0 |
783,778 | Estimation of stomatal ozone uptake of deciduous trees in East Asia | Hoshika, Y; Hajima, T; Shimizu, Y; Takigawa, M; Omasa, K | 2,011 | To assess ozone risks to temperate deciduous forest trees in
East Asia, the stomatal ozone uptake was estimated based on a flux-based modeling approach. In
this model, key parameters were obtained from scientific literatures on deciduous tree species in
East Asia. In addition, regional characteristics of the leaf... | 0 |
786,101 | Measurement of western U.S. baseline ozone from the surface to the tropopause and assessment of downwind impact regions | Cooper, OR; Oltmans, SJ; Johnson, BJ; Brioude, J; Angevine, W; Trainer, M; Parrish, DD; Ryerson, TR; Pollack, I; Cullis, PD; Ives, MA; Tarasick, DW; Al-Saadi, J; Stajner, I | 2,011 | Since 1997, baseline ozone monitoring from the surface to the tropopause along the U. S. west coast has been limited to the weekly ozonesondes from Trinidad Head, California. To explore baseline ozone at other latitudes, an ozonesonde network was implemented during spring 2010, including four launch sites along the Cal... | 1 |
783,793 | Ecosystem-scale biosphere?atmosphere interactions of a hemiboreal mixed forest stand at Jarvselja, Estonia | Noe, SM; Kimmel, V; Huve, K; Copolovici, L; Portillo-Estrada, M; Puttsepp, U; J?giste, K; Niinemets, U; Hortnagl, L; Wohlfahrt, G | 2,011 | During two measurement campaigns, from August to September 2008 and 2009, we quantified the major ecosystem fluxes in a hemiboreal forest ecosystem in Jaryselja, Estonia. The main aim of this study was to separate the ecosystem flux components and gain insight into the performance of a multi-species multilayered tree s... | 0 |
749,704 | Impacts of HOx regeneration and recycling in the oxidation of isoprene: Consequences for the composition of past, present and future atmospheres | Archibald, AT; Levine, JG; Abraham, NL; Cooke, MC; Edwards, PM; Heard, DE; Jenkin, ME; Karunaharan, A; Pike, RC; Monks, PS; Shallcross, DE; Telford, PJ; Whalley, LK; Pyle, JA | 2,011 | A global chemistry-climate model is used to assess the impact on atmospheric composition of the regeneration and recycling of HO x in the photo-oxidation of isoprene. The impact is explored subject to present-day, pre-industrial and future climate/emission scenarios. Our calculations show that, in all cases, the inclus... | 1 |
2,083,860 | Importance of secondary sources in the atmospheric budgets of formic and acetic acids | Paulot, F; Wunch, D; Crounse, JD; Toon, GC; Millet, DB; Decarlo, PF; Vigouroux, C; Deutscher, NM; Abad, GG; Notholt, J; Warneke, T; Hannigan, JW; Warneke, C; de Gouw, JA; Dunlea, EJ; De Maziere, M; Griffith, DWT; Bernath, P; Jimenez, JL; Wennberg, PO | 2,011 | We present a detailed budget of formic and acetic acids, two of the most abundant trace gases in the atmosphere. Our bottom-up estimate of the global source of formic and acetic acids are similar to 1200 and similar to 1400 Gmol yr(-1), dominated by photochemical oxidation of biogenic volatile organic compounds, in par... | 0 |
783,801 | Effects of ambient O3 on wheat during reproductive development: Gas exchange, photosynthetic pigments, chlorophyll fluorescence, and carbohydrates | Rai, R; Agrawal, M; Agrawal, SB | 2,011 | The current concentrations of O-3 have been shown to cause
significant negative effects on crop yield. The present levels of ozone may not induce visible
symptoms in most of plants, but can result in substantial losses in reproductive output. This
paper considers the impact of ambient O-3 on gas exchange, photosy... | 0 |
758,736 | The importance of stratospheric?tropospheric transport in affecting surface ozone concentrations in the western and northern tier of the United States | Lefohn, AS; Wernli, H; Shadwick, D; Limbach, S; Oltmans, SJ; Shapiro, M | 2,011 | Stratospheric?tropospheric exchange (STE) processes contribute at both high and low-elevation monitoring sites to background ozone (O3) concentrations. This study addresses the importance of stratospheric intrusions contributing to enhanced hourly average surface O3 concentrations (i.e., ?50 ppb) at 12 O3 monitoring st... | 1 |
757,888 | Impacts of tropospheric ozone and climate change on net primary productivity and net carbon exchange of China's forest ecosystems | Ren, W; Tian, H; Tao, B; Chappelka, A; Sun, G; Lu, C; Liu, M; Chen, G; Xu, X | 2,011 | Aim
<br>
<br>We investigated how ozone pollution and climate change/variability have interactively affected net primary productivity (NPP) and net carbon exchange (NCE) across China's forest ecosystem in the past half century.
<br>
<br>Location
<br>
<br>Continental China.
<br>
<br>Methods
<br>
<br>Using the dynamic lan... | 0 |
783,326 | China's terrestrial carbon balance: Contributions from multiple global change factors | Tian, H; Melillo, J; Lu, C; Kicklighter, D; Liu, M; Ren, W; Xu, X; Chen, G; Zhang, C; Pan, S; Liu, J; Running, S | 2,011 | The magnitude, spatial, and temporal patterns of the terrestrial carbon sink and the underlying mechanisms remain uncertain and need to be investigated. China is important in determining the global carbon balance in terms of both carbon emission and carbon uptake. Of particular importance to climate-change policy and c... | 0 |
677,549 | U.S. Census Bureau | null | 2,011 | null | 1 |
759,127 | Human health risk in relation to air quality in two municipalities in an industrialized area of Northern Italy | Fattore, E; Paiano, V; Borgini, A; Tittarelli, A; Bertoldi, M; Crosignani, P; Fanelli, R | 2,011 | Air quality is one of the major environmental issues related to human health, and people and authorities are increasingly aware and concerned about it, asking to be involved in decisions whose fallout can have consequences on their health. The objectives of the present study were to provide quantitative data on the imp... | 0 |
787,141 | [Ground-level ozone - A threat for biodiversity?] | Weigel, HJ; Dauber, J; Bender, J | 2,011 | The concentrations of various compounds in the atmosphere such as tropospheric ozone have rapidly changed during the last century, and they continue to change. While it has been shown that ozone concentrations have significant adverse effects on crop yields, forest growth and species composition, the impacts of ozone o... | 0 |
785,545 | Recent decreases in fossil-fuel emissions of ethane and methane derived from firn air | Aydin, M; Verhulst, KR; Saltzman, ES; Battle, MO; Montzka, SA; Blake, DR; Tang, Q; Prather, MJ | 2,011 | Methane and ethane are the most abundant hydrocarbons in the atmosphere and they affect both atmospheric chemistry and climate. Both gases are emitted from fossil fuels and biomass burning, whereas methane (CH(4)) alone has large sources from wetlands, agriculture, landfills and waste water. Here we use measurements in... | 0 |
785,554 | Errata in 'Contributions of natural emissions to ozone and PM 2.5 as simulated by the Community Multiscale Air Quality (CMAQ) model' | Mueller, SF; Mallard, JW | 2,011 | null | 1 |
832,590 | Do Some NO(x) Emissions Have Negative Environmental Damages? Evidence and Implications for Policy | Fraas, A; Lutter, R | 2,011 | null | 0 |
832,996 | Can algal uptake stop NO3(-) pollution | Baulch, HM; Stanley, EH; Bernhardt, ES | 2,011 | null | 0 |
733,109 | Changes in the proteome of juvenile European beech following three years exposure to free-air elevated ozone | Kerner, R; Winkler, J; Dupuy, J; Jurgensen, M; Lindermayr, C; Ernst, D; Muller-Starck, G | 2,011 | Abstract: Tropospheric ozone, one of the most phytotoxic air pollutants, may specially impose in long-lived forest trees substantial reduction in productivity and biomass. European beech saplings grown in lysimeter around areas were used to monitor proteomic changes upon elevated ozone concentrations following four veg... | 1 |
786,574 | Semi?long-term mortality effects of ozone | Ito, K | 2,011 | null | 0 |
837,313 | Comment on "Do Some NO(x) Emissions Have Negative Environmental Damages? Evidence and Implications for Policy" | Fann, NL; Phillips, DS; Jang, DC; Akhtar, DF | 2,011 | null | 0 |
852,471 | A small change in FVC but a big change for IPF: Defining the minimal clinically important difference | Behr, J | 2,011 | null | 0 |
834,902 | Lung function decrements with 0.06 ppm ozone exposure are of limited clinical and public health significance | Prueitt, RL | 2,011 | Kim and coworkers (1) exposed 59 healthy, exercising young adults to 0.06 ppm ozone for 6.6 hours under controlled chamber conditions and observed a mean percent-change in FEV1 (clean-air adjusted) of ?1.75 (95% confidence interval, ?3.0 to ?0.5) and an increase in neutrophilic inflammation of the airways, with no stat... | 0 |
778,742 | Ozone database in support of CMIP5 simulations: results and corresponding radiative forcing | Cionni, I; Eyring, V; Lamarque, JF; Randel, WJ; Stevenson, DS; Wu, F; Bodeker, GE; Shepherd, TG; Shindell, DT; Waugh, DW | 2,011 | A continuous tropospheric and stratospheric vertically resolved ozone time series, from 1850 to 2099, has been generated to be used as forcing in global climate models that do not include interactive chemistry. A multiple linear regression analysis of SAGE I+II satellite observations and polar ozonesonde measurements i... | 0 |
677,545 | SMOKE | null | 2,011 | This is the official SMOKE website hosted by the Center for Environmental Modeling for Policy Development (CEMPD) at the University of North Carolina at Chapel Hill. SMOKE is an active open-source development project supported and distributed by the CEMPD through the Community Modeling and Analysis System Center. | 1 |
749,707 | Contributions of natural emissions to ozone and PM 2.5 as simulated by the Community Multiscale Air Quality (CMAQ) model | Mueller, SF; Mallard, JW | 2,011 | The relative roles of natural and anthropogenic sources in determining ozone and fine particle concentrations over the continental United States (U.S.) are investigated using an expanded emissions inventory of natural sources and an updated version of the Community Multiscale Air Quality (CMAQ) model. Various 12-month ... | 1 |
749,252 | Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: A role for heat shock protein 70 | Bauer, AK; Rondini, EA; Hummel, KA; Degraff, LM; Walker, C; Jedlicka, AE; Kleeberger, SR | 2,011 | Background. Toll-like receptor 4 (TLR4) is involved in ozone (O3)-induced pulmonary hyperpermeability and inflammation, though the downstream signaling events are unknown. Objectives. The aims of our study were to determine the mechanism through which TLR4 modulates O3-induced pulmonary responses and to utilize transcr... | 1 |
749,415 | Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia | Thepot, S; Lainey, E; Cluzeau, T; Sebert, M; Leroy, C; Ades, L; Tailler, M; Galluzzi, L; Baran-Marszak, F; Roudot, H; Eclache, V; Gardin, C; de Botton, S; Auberger, P; Fenaux, P; Kroemer, G; Boehrer, S | 2,011 | The deregulation of the DNA damage response (DDR) can contribute to leukemogenesis and favor the progression from myelodysplastic syndrome (MDS) to acute myeloid leukemia (AML). Since hypomethylating agents-notably azacitidine-constitute an efficient therapy for patients with high-risk MDS, we assessed whether such com... | 0 |
757,782 | Acute effects of air pollution on peak expiratory flow rates and symptoms among asthmatic patients in Chiang Mai, Thailand | Wiwatanadate, P; Liwsrisakun, C | 2,011 | The open burnings and forest fires have been recognized as the major sources of severe air pollution in the upper north of Thailand; however, there have been no clear evidences to show the associations between the air pollution and health effects in the area. We assessed the effects of air pollutants on the peak expira... | 1 |
749,269 | Effect of maternal exposure to ozone on reproductive outcome and immune, inflammatory, and allergic responses in the offspring | Sharkhuu, T; Doerfler, DL; Copeland, C; Luebke, RW; Gilmour, MI | 2,011 | There is growing concern that exposure to air pollutants during pregnancy affects health outcomes in the offspring due to alterations in the development of immune and other homeostatic processes. To assess the risks of maternal inhalation exposure to ozone (O(3)), timed pregnant BALB/c mice were exposed to different co... | 1 |
749,246 | Do corticosteroids have a role in preventing or reducing acute toxic lung injury caused by inhalation of chemical agents | de Lange, DW; Meulenbelt, J | 2,011 | To assess the evidence that treatment with corticosteroids improves the outcome in those exposed to lung-damaging agents.<br /><br /> We searched Pubmed, Toxnet, Cochrane database, Google Scholar, and Embase from 1966 to January 2010 using the search terms "steroid", "corticosteroid", "lung injury", "lung damage", and ... | 0 |
699,417 | Ambient temperature, air pollution, and heart rate variability in an aging population | Ren, C; Park, S; O'Neill, M; Sparrow, D; Vokonas, P; Schwartz, J | 2,011 | Studies show that ambient temperature and air pollution are associated with cardiovascular disease and that they may interact to affect cardiovascular events. However, few epidemiologic studies have examined mechanisms through which ambient temperature may influence cardiovascular function. The authors examined whether... | 0 |
735,953 | Windsor, Ontario Exposure Assessment Study: Design and methods validation of personal, indoor, and outdoor air pollution monitoring | Wheeler, AJ; Xu, X; Kulka, R; You, H; Wallace, L; Mallach, G; Van Ryswyk, K; Macneill, M; Kearney, J; Rasmussen, PE; Dabek-Zlotorzynska, E; Wang, D; Poon, R; Williams, R; Stocco, C; Anastassopoulos, A; Miller, JD; Dales, R; Brook, , JR | 2,011 | The Windsor, Ontario Exposure Assessment Study evaluated the contribution of ambient air pollutants to personal and indoor exposures of adults and asthmatic children living in Windsor, Ontario, Canada. In addition, the role of personal, indoor, and outdoor air pollution exposures upon asthmatic children's respiratory h... | 0 |
785,562 | Using a chemistry transport model to account for the spatial variability of exposure concentrations in epidemiologic air pollution studies | Valari, M; Menut, L; Chatignoux, E | 2,011 | Environmental epidemiology and more specifically time-series analysis have traditionally used area-averaged pollutant concentrations measured at central monitors as exposure surrogates to associate health outcomes with air pollution. However, spatial aggregation has been shown to contribute to the overall bias in the e... | 0 |
749,439 | Epithelial, dendritic, and CD4(+) T cell regulation of and by reactive oxygen and nitrogen species in allergic sensitization | Ckless, K; Hodgkins, SR; Ather, JL; Martin, R; Poynter, ME | 2,011 | Background
While many of the contributing cell types and mediators of allergic asthma are known, less well understood are the factors that induce allergy in the first place. Amongst the mediators speculated to affect initial allergen sensitization and the development of pathogenic allergic responses to innocuous inhal... | 0 |
677,486 | Quality indicator assessment reports | null | 2,011 | null | 0 |
749,438 | Epigenetics of asthma | Durham, AL; Wiegman, C; Adcock, IM | 2,011 | Asthma is caused by both heritable and environmental factors. It has become clear that genetic studies do not adequately explain the heritability and susceptibility to asthma. The study of epigenetics, heritable non-coding changes to DNA may help to explain the heritable component of asthma. Additionally, epigenetic mo... | 0 |
749,437 | Nox enzymes in allergic airway inflammation | Der Vliet, AV | 2,011 | Chronic airway diseases such as asthma are linked to oxidative environmental factors and are commonly associated with increased production of reactive oxygen species (ROS). Therefore, it is commonly assumed that oxidative stress is an important contributing factor to asthma disease pathogenesis and that antioxidant str... | 0 |
783,762 | The OzT8 locus in rice protects leaf carbon assimilation rate and photosynthetic capacity under ozone stress | Chen, CP; Frei, M; Wissuwa, M | 2,011 | Tropospheric ozone (O?) is a phytotoxic air pollutant whose current background concentrations in parts of East Asia have caused estimated rice yield losses of up to 20%; currently, however, little is known about the mechanisms of O? tolerance in rice. We previously identified a quantitative trait locus (QTL) in rice ca... | 0 |
783,817 | Water, heat, and airborne pollutants effects on transpiration of urban trees | Wang, H; Ouyang, Z; Chen, W; Wang, X; Zheng, H; Ren, Y | 2,011 | Transpiration rates of six urban tree species in Beijing evaluated by thermal dissipation method for one year were correlated to environmental variables in heat, water, and pollutant groups. To sort out colinearity of the explanatory variables, their individual and joint contributions to variance of tree transpiration ... | 0 |
785,524 | Portable Ozone Monitoring Systems (POMS) | null | 2,011 | A new option for ozone monitoring recently became available when a small low-power ozone analyzer was offered commercially. The National Park Service (NPS) has configured the analyzers with a datalogger, weather measurements, and solar-power on an open-frame system that is transportable and has low site impact. Two POM... | 0 |
749,401 | [Genetic polymorphisms and xenobiotic exposure in infantile asthma] | Mu?oz Soto, RB; Albores Medina, A | 2,011 | Together with industrial development in Mexico has come a major increase in the generation of air pollutants. Some of these pollutants include compounds such as ozone, that like tobacco smoke, are related to the severity of certain respiratory diseases such as asthma. Although asthma affects people of all ages, it has ... | 0 |
783,760 | Physiological, anatomical and biomass partitioning responses to ozone in the Mediterranean endemic plant Lamottea dianae | Calatayud, V; Garcia-Breijo, FJ; Cervero, J; Reig-Armi?ana, J; Sanz, MJ | 2,011 | Ozone effects on the perennial forb Lamottea dianae were studied in an open-top chamber experiment. Ozone was found to induce reductions in CO? assimilation and water use efficiency in the leaves of this species. These reductions were mainly related to a decline in the in vivo CO? fixation capacity of Rubisco (V(c,max)... | 0 |
757,785 | Estimation of age-related vulnerability to air pollution: assessment of respiratory health at local scale | Namdeo, A; Tiwary, A; Farrow, E | 2,011 | This paper demonstrates association of short-term variation in pollution and health outcomes within the same geographical area for a typical urban setting in the northern part of the UK from time series analysis. It utilises publicly available datasets for regulated air pollutants (PM??, NO?, SO?, CO and O?), meteorolo... | 0 |
749,667 | Ambient air pollution and lipoprotein-associated phospholipase A2 in survivors of myocardial infarction | Bruske, I; Hampel, R; Baumgartner, Z; Ruckerl, R; Greven, S; Koenig, W; Peters, A; Schneider, A | 2,011 | Background: Increasing evidence suggests a proatherogenic role for lipoprotein-associated phospholipase A2 (Lp-PLA2). A meta-analysis of published cohorts has shown that Lp-PLA2 is an independent predictor of coronary heart disease events and stroke.Objective: In this study, we investigated whether the association betw... | 0 |
749,272 | A model of chronic inflammation and pulmonary emphysema after multiple ozone exposures in mice | Triantaphyllopoulos, K; Hussain, F; Pinart, M; Zhang, M; Li, F; Adcock, I; Kirkham, P; Zhu, J; Chung, KF | 2,011 | Oxidative stress plays a role in the pathophysiology of emphysema through the activation of tissue proteases and apoptosis. We examined the effects of ozone exposure by exposing BALB/c mice to either a single 3-h exposure or multiple exposures over 3 or 6 wk, with two 3-h exposures per week. Compared with air-exposed m... | 0 |
749,440 | Leukotrienes and airway inflammation | Okunishi, K; Peters-Golden, M | 2,011 | Asthma is a common chronic inflammatory disease of the airways characterized by airway obstruction and hyperresponsiveness. Leukotrienes (LTs) are lipid mediators that contribute to many aspects of asthma pathogenesis. As the LT pathway is relatively steroid-resistant, its blockade by alternative strategies is a desira... | 0 |
749,266 | Prolonged ozone exposure effects behaviour, hormones and respiratory muscles in young female rats | Martrette, JM; Thornton, SN; Trabalon, M | 2,011 | This study evaluated behavioural and physiological (hormonal status, muscle structure) affects of prolonged ozone exposure in young females rats. Female Wistar rats were exposed at 0.12ppm of ozone during 6h per day for 15days. Prolonged ozone exposure, though not continuous, produced remarkable behavioural disturbance... | 1 |
2,652,698 | Evaluation of the ozone-related risk for winter wheat at local scale with the CRO3PS model | Grunhage, L; Braden, H; Bender, J; Burkart, S; Lehmann, Y; Schroder, M | 2,011 | Tropospheric ozone poses a critical threat and a challenging problem to present and future, e.g. food security. In the recent years a stomatal flux-based risk evaluation methodology at leaf level was established in the context of the Convention on Long-Range Transboundary Air Pollution (LRTAP) for crops, forest trees a... | 0 |
737,603 | Biochemical effects of ozone on asthma during postnatal development | Auten, RL; Foster, WM | 2,011 | BACKGROUND: Ozone exposure during early life has the potential to contribute to the development of asthma as well as to exacerbate underlying allergic asthma. SCOPE OF REVIEW: Developmentally regulated aspects of sensitivity to ozone exposure and downstream biochemical and cellular responses. MAJOR CONCLUSIONS: Develop... | 1 |
733,096 | Investigations on N-rich protein (NRP) of Arabidopsis thaliana under different stress conditions | Hoepflinger, MC; Pieslinger, AM; Tenhaken, R | 2,011 | Stress response and adaptation are important physiological mechanisms in plants. As plants are not able to avoid stressful environments by moving away, as animals, they have developed diverse mechanisms to respond to stressful situations. One of the genes involved in these mechanisms is NRP (Asparagine-rich protein or ... | 0 |
749,443 | Glutathione biochemistry in asthma | Reynaert, NL | 2,011 | Oxidative stress in an important hallmark of asthma, and much research has therefore focused on the predominant antioxidant in the lungs, namely the tripeptide glutathione. In lung samples of patients with asthma increased levels of glutathione are typically observed, which appear to relate to the level of pulmonary in... | 0 |
783,772 | Growth at elevated ozone or elevated carbon dioxide concentration alters antioxidant capacity and response to acute oxidative stress in soybean (Glycine max) | Gillespie, KM; Rogers, A; Ainsworth, EA | 2,011 | Soybeans (Glycine max Merr.) were grown at elevated carbon dioxide concentration ([CO(2)]) or chronic elevated ozone concentration ([O(3)]; 90 ppb), and then exposed to an acute O(3) stress (200 ppb for 4 h) in order to test the hypothesis that the atmospheric environment alters the total antioxidant capacity of plants... | 0 |
749,399 | The effect of rectal ozone on the portal vein oxygenation and pharmacokinetics of propranolol in liver cirrhosis (a preliminary human study) | Zaky, S; Fouad, EA; Kotb, HI | 2,011 | The aim of this study was to investigate the effect of rectal ozone on portal vein oxygenation and the pharmacokinetic changes of propranolol in patients with liver cirrhosis.<br /><br /> Fifteen patients with liver cirrhosis were included They were given a fixed oral dose of propranolol 80mg on the morning of day 1 af... | 0 |
778,755 | Impacts of changes in land use and land cover on atmospheric chemistry and air quality over the 21st century | Wu, S; Mickley, LJ; Kaplan, JO; Jacob, DJ | 2,011 | The effects of future land use and land cover change on the chemical composition of the atmosphere and air quality are largely unknown. To investigate the potential effects associated with future changes in vegetation driven by atmospheric CO2 concentrations, climate, and anthropogenic land use over the 21st century, w... | 0 |
783,766 | What can enzymes of C? photosynthesis do for C? plants under stress | Doubnerova, V; Ryslava, H | 2,011 | Phosphoenolpyruvate carboxylase (PEPC), NADP-malic enzyme (NADP-ME), and pyruvate, phosphate dikinase (PPDK) participate in the process of concentrating CO? in C? photosynthesis. Non-photosynthetic counterparts of these enzymes, which are present in all plants, play important roles in the maintenance of pH and replenis... | 0 |
749,442 | Viruses and asthma | Dulek, DE; Peebles, RS | 2,011 | BACKGROUND: Viral respiratory infection has long been known to influence the occurrence of asthma exacerbations. Over the last 20years much effort has been put into clarifying the role that viral respiratory infections play in the eventual development of asthma. SCOPE OF REVIEW: In this review we give a general backgro... | 0 |
682,413 | Acute effects of air pollution on pediatric asthma exacerbation: Evidence of association and effect modification | Samoli, E; Nastos, PT; Paliatsos, AG; Katsouyanni, K; Priftis, KN | 2,011 | We investigated the short-term previous termeffectsnext term of particulate matter with aerodynamic diameter <10 ?g/m3 (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3) on previous termpediatric asthmanext term emergency admissions in Athens, Greece over the period 2001?2004. We explored previous term... | 0 |
758,859 | Spatial heterogeneity of PM10 and O3 in Sao Paulo, Brazil, and implications for human health studies | Bravo, MA; Bell, ML | 2,011 | Developing exposure estimates is a challenging aspect of investigating the health effects of air pollution. Pollutant levels recorded at centrally located ambient air quality monitors in a community are commonly used as proxies for population exposures. However, if ample intraurban spatial variation in pollutants exist... | 1 |
749,663 | The international collaboration on air pollution and pregnancy outcomes: Initial results | Parker, JD; Rich, DQ; Glinianaia, SV; Leem, JH; Wartenberg, D; Bell, ML; Bonzini, M; Brauer, M; Darrow, L; Gehring, U; Gouveia, N; Grillo, P; Ha, E; van den Hooven, EH; Jalaludin, B; Jesdale, BM; Lepeule, J; Morello-Frosch, R; Morgan, GG; Slama, R; Pierik, FH; Pesatori, AC; Sathyanarayana, S; Seo, J; Strickland, M; Tam... | 2,011 | Background: The findings of prior studies of air pollution effects on adverse birth outcomes are difficult to synthesize because of differences in study design.Objectives: The International Collaboration on Air Pollution and Pregnancy Outcomes was formed to understand how differences in research methods contribute to v... | 0 |
689,856 | Short-term association between exposure to ozone and mortality in Oporto, Portugal | de Almeida, SP; Casimiro, E; Calheiros, J | 2,011 | Exposures to air pollution in developed countries have generally decreased over the last two decades. However, many recent epidemiological studies have consistently shown positive associations between low-level exposure to air pollutants and health outcomes. In Portugal, very few studies have analysed the acute effect ... | 0 |
749,441 | T(H)17 cells in asthma and inflammation | Aujla, SJ; Alcorn, JF | 2,011 | The chronic airway disease asthma causes significant burden to patients as well as the healthcare system with limited options for prevention or cure. Inadequate treatment strategies are most likely due to the complex heterogeneous nature of asthma. Furthermore, the severe asthma phenotype is characterized by the lack o... | 0 |
749,267 | Effects of ozone oxidative preconditioning on different hepatic biomarkers of oxidative stress in endotoxic shock in mice | Rodriguez, ZZ; Guanche, D; Alvarez, RG; Martinez, Y; Alonso, Y; Schulz, S | 2,011 | In endotoxic shock, variations are known to occur in different biochemical parameters of oxidative stress. Ozone oxidative preconditioning (OOP) is a good candidate to restore the redox balance on different tissue. This investigation examined the effect of OOP on different biomarkers of oxidative stress in hepatic tiss... | 0 |
688,909 | Exposure to environmental microorganisms and childhood asthma | Ege, MJ; Mayer, M; Normand, AC; Genuneit, J; Cookson, WOCM; Braun-Fahrlander, C; Heederik, D; Piarroux, R; von Mutius, E | 2,011 | Background: Children who grow up in environments that afford them a wide range of microbial exposures, such as traditional farms, are protected from childhood asthma and atopy. In previous studies, markers of microbial exposure have been inversely related to these conditions. Methods: In two cross-sectional studies, we... | 0 |
699,956 | Does exposure to air pollution in urban parks have socioeconomic, racial or ethnic gradients | Su, J; Jerrett, M; de Nazelle, A; Wolch, J | 2,011 | Little is known about the levels of air pollution at public parks where regular exercise takes place or in park-adjacent neighborhoods where people have easy access to parks. In this study we investigated the ambient concentrations of criteria pollutants nitrogen dioxide (NO(2)), fine particulate (PM(2.5)) and ozone (O... | 0 |
749,402 | SB-656933, a novel CXCR2 selective antagonist, inhibits ex-vivo neutrophil activation and ozone-induced airway inflammation in humans | Lazaar, AL; Sweeney, LE; Macdonald, AJ; Alexis, NE; Chen, C; Tal-Singer, R | 2,011 | What is already known about this subject Receptor antagonists that block the binding of chemokines such as CXCL8 (IL-8) are effective in animals models of neutrophil-mediated inflammation. It has been hypothesized that selective inhibition of neutrophil trafficking and activation may be a useful adjunct for the treatme... | 0 |
783,802 | Cellulose and lignin biosynthesis is altered by ozone in wood of hybrid poplar (Populus tremula ? alba) | Richet, N; Afif, D; Huber, F; Pollet, B; Banvoy, J; El Zein, R; Lapierre, C; Dizengremel, P; Perre, P; Cabane, M | 2,011 | Wood formation in trees is a dynamic process that is strongly affected by environmental factors. However, the impact of ozone on wood is poorly documented. The objective of this study was to assess the effects of ozone on wood formation by focusing on the two major wood components, cellulose and lignin, and analysing a... | 0 |
749,259 | In utero tobacco smoke exposure alters pulmonary responses of newborn rats to ozone | Han, SG; Bhoopalan, V; Akinbiyi, T; Gairola, CG; Bhalla, DK | 2,011 | Prenatal tobacco smoke (TS) exposure has been implicated in various adverse health outcomes in the offspring, including poor development of lung and immune system, which in turn can alter the response of neonates to environmental challenges. This study was performed to determine whether in utero exposure to TS influenc... | 1 |
749,258 | Ozone inhalation activates stress-responsive regions of the CNS | Gackiere, F; Saliba, L; Baude, A; Bosler, O; Strube, C | 2,011 | J. Neurochem. (2011) 117, 961-972. ABSTRACT: Ozone (O(3) ), a major component of air pollution, has considerable impact on public health. Besides the well-described respiratory tract inflammation and dysfunctions, there is accumulating evidence indicating that O(3) exposure affects brain functions. However, the mechani... | 1 |
783,759 | Growth of soybean at future tropospheric ozone concentrations decreases canopy evapotranspiration and soil water depletion | Bernacchi, CJ; Leakey, AD; Kimball, BA; Ort, DR | 2,011 | Tropospheric ozone is increasing in many agricultural regions resulting in decreased stomatal conductance and overall biomass of sensitive crop species. These physiological effects of ozone forecast changes in evapotranspiration and thus in the terrestrial hydrological cycle, particularly in intercontinental interiors.... | 0 |
749,407 | In vitro stability and metabolism of O2', O3', O5'-tri-acetyl-N(6)-(3-hydroxylaniline) adenosine in rat, dog and human plasma: Chemical hydrolysis and role of plasma esterases | Liu, Y; He, J; Abliz, Z; Zhu, H | 2,011 | O2', O3', O5'-tri-acetyl-N(6)-(3-hydroxylaniline)adenosine (WS070117), a new structure-type lipid regulator, is being developed in pre-clinical study. In order to monitor drug kinetics it is essential to understand pre-analytical factors that may affect drug assay. In vitro stability and metabolism were investigated us... | 0 |
757,783 | Outdoor air pollution and asthma in children | Tzivian, L | 2,011 | Background. Asthma, a chronic inflammatory disease of the airways, is associated with reversible airway obstruction and hyperresponsiveness to triggers; clinical symptoms include wheezing, episodic cough, shortness of breath, and increased mucous production. Ambient or outdoor environmental exposure to ozone, particula... | 0 |
696,634 | Elevated ozone reduces methane emissions from peatland mesocosms | Toet, S; Ineson, P; Peacock, S; Ashmore, M | 2,011 | Although the effects of elevated ozone on aboveground carbon (C) assimilation are well understood, its effects on soil C fluxes are less certain. Mesocosms taken from a lowland raised bog in northern England were exposed in open-top chambers for 2 years to ambient air or ambient air plus ozone elevated for 8 h day-1 by... | 1 |
783,792 | Growth, leaf traits and litter decomposition of roadside hybrid aspen (Populus tremula L.? P. tremuloides Michx.) clones | Nikula, S; Manninen, S; Vapaavuori, E; Pulkkinen, P | 2,011 | Road traffic contributes considerably to ground-level air pollution and is therefore likely to affect roadside ecosystems. Differences in growth and leaf traits among 13 hybrid aspen (Populus tremula ? P. tremuloides) clones were studied in relation to distance from a motorway. The trees sampled were growing 15 and 30 ... | 0 |
757,784 | Outdoor air pollution and respiratory health in patients with COPD | Peacock, JL; Anderson, HR; Bremner, SA; Marston, L; Seemungal, TA; Strachan, DP; Wedzicha, JA | 2,011 | Objectives Time series studies have shown adverse effects of outdoor air pollution on mortality and hospital admissions in patients with chronic obstructive pulmonary disease (COPD) but panel studies have been inconsistent. This study investigates short-term effects of outdoor nitrogen dioxide, ozone, sulfur dioxide, p... | 1 |
783,780 | Highly contrasting effects of different climate forcing agents on terrestrial ecosystem services | Huntingford, C; Cox, PM; Mercado, LM; Sitch, S; Bellouin, N; Boucher, O; Gedney, N | 2,011 | Many atmospheric constituents besides carbon dioxide (CO(2)) contribute to global warming, and it is common to compare their influence on climate in terms of radiative forcing, which measures their impact on the planetary energy budget. A number of recent studies have shown that many radiatively active constituents als... | 0 |
749,409 | Efficacy of the pan-selectin antagonist Bimosiamose on ozone-induced airway inflammation in healthy subjects - A double blind, randomized, placebo-controlled, cross-over clinical trial | Kirsten, A; Watz, H; Kretschmar, G; Pedersen, F; Bock, D; Meyer-Sabellek, W; Magnussen, H | 2,011 | Selectins, a family of cell adhesion molecules, are involved in the activation and extravasation of leukocytes in inflammatory diseases. Inhalation of ozone induces an inflammation of the airways, which is dominated by neutrophils. We investigated the effect of repeated inhalations of the pan-selectin antagonist Bimosi... | 0 |
733,688 | Particulate air pollution exposure and C-reactive protein during early pregnancy | Lee, PC; Talbott, EO; Roberts, JM; Catov, JM; Sharma, RK; Ritz, B | 2,011 | BACKGROUND: It is not well understood how air pollution leads to adverse pregnancy outcomes. One pathway may be through C-reactive protein, a biomarker of systemic inflammation that has been reported to increase the risk of preterm delivery. We examined whether air pollution influences serum concentrations of C-reactiv... | 0 |
786,832 | Kinetics of the reactions of OH radicals with 2-methoxy-6-(trifluoromethyl)pyridine, diethylamine, and 1,1,3,3,3-pentamethyldisiloxan-1-ol at 298 ? 2 K | Tuazon, EC; Martin, P; Aschmann, SM; Arey, J; Atkinson, R | 2,011 | Rate constants for the reactions of 2-methoxy-6-(trifluoromethyl)pyridine, diethylamine, and 1,1,3,3,3-pentamethyldisiloxan-1-ol with OH radicals have been measured at 298 +/- 2 K using a relative rate method. The measured rate constants (cm(3) molecule(-1) s(-1)) are (1.54 +/- 0.21) x 10(-12) for 2-methoxy-6-(trifluor... | 0 |
783,786 | Cadmium pollution enhanced ozone damage to winter wheat: Biochemical and physiological evidences | Li, Y; Li, C; Zheng, Y; Wu, G; Wuyun, T; Xu, H; He, X; Jiang, G | 2,011 | Combined effects of ozone (O3) and cadmium (Cd) on growth and physiology of winter wheat (Triticum aestivum L. cv. JM22) were determined. Wheat plants were grown without or with Cd and exposed to charcoal-filtered air (< 10 ppb O3) or elevated O3 (80 ? 5 ppb, 7 hr/day) for 20 days. Results showed that O3 considerably d... | 0 |
758,519 | Surface reaction rate and probability of ozone and alpha-terpineol on glass, polyvinyl chloride, and latex paint surfaces | Shu, S; Morrison, GC | 2,011 | Ozone can react homogeneously with unsaturated organic compounds in buildings to generate undesirable products. However, these reactions can also occur on indoor surfaces, especially for low-volatility organics. Conversion rates of ozone with ?-terpineol, a representative low-volatility compound, were quantified on sur... | 1 |
749,410 | Exposure to 1-bromopropane causes degeneration of noradrenergic axons in the rat brain | Mohideen, SS; Ichihara, G; Ichihara, S; Nakamura, S | 2,011 | 1-Bromopropane (1-BP) has been used as an alternative to ozone-depleting solvents. Previous studies showed that 1-BP is neurotoxic in animals and humans. In humans, exposure to 1-BP caused various neurological and neurobehavioral symptoms or signs including depressive or irritated mood. However, the neurobiological cha... | 0 |
749,268 | Comparison of ozone-specific (OZAC) and oxygen radical (ORAC) antioxidant capacity assays for use with nasal lavage fluid | Rutkowski, JM; Santiag, LY; Ben-Jebria, A; Ultman, JS | 2,011 | Antioxidants in respiratory mucus protect the underlying airway epithelium from damage by ozone (O(3)), a common outdoor air pollutant. To understand O(3)-antioxidant interactions and the variation of these interactions among individuals, in vitro assays are needed to measure the total antioxidant capacity of airway la... | 1 |
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