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ADNI Mini v1.3 selection (local, unpublished)

This directory contains the selected manifest and coverage report for the unpublished ADNI v1.3 evaluation cohort. It has not been uploaded to Hugging Face and does not contain Arrow shards yet.

Cohort

  • 1,200 subjects and one baseline T1w scan per subject
  • 450 CN, 500 MCI, 250 AD
  • 600 Female, 600 Male
  • 286 CN amyloid-positive participants, all retained within the 450-CN quota

v1.3 changes from v1.2

  • Retired LDELTOTAL slope and amygdala slope.
  • Added RAVLT 30-minute delayed recall and RAVLT learning (sum of AVTOT1-5) annualized 48-month slopes.
  • Added FreeSurfer 7 bilateral entorhinal cortical-thickness annualized 48-month slope, calculated as mean(ST24TA, ST83TA) and excluding explicit temporal-lobe QC failures.
  • Retained CN A+ to MCI/AD within 36 months, with a strict CN plus amyloid-positive gate.
  • Added CN A+ restricted variants of ADAS13, both RAVLT, hippocampus, ventricles, and entorhinal thickness slopes.

Final coverage

Task N Events
MCI to AD within 3y 450 169
CN A+ to MCI/AD within 3y 187 39
ADAS13 slope, 48m 973 -
RAVLT delayed slope, 48m 975 -
RAVLT learning slope, 48m 977 -
Hippocampus slope, 48m 925 -
Ventricle slope, 48m 925 -
Entorhinal thickness slope, 48m 878 -
CN A+ ADAS13 slope, 48m 187 -
CN A+ RAVLT delayed slope, 48m 189 -
CN A+ RAVLT learning slope, 48m 189 -
CN A+ hippocampus slope, 48m 164 -
CN A+ ventricle slope, 48m 164 -
CN A+ entorhinal thickness slope, 48m 143 -

selected_manifest.csv is the reproducible local selection. Rebuild it with:

.venv/bin/python datasets/adni/select_v13.py \
  --n-cn 450 --n-mci 450 --n-ad 300 \
  --output artifacts/adni-mini-v1-3/selected_manifest.csv
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