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SQuAD
Two chains of DNA twist around each other to form a DNA double helix with the phosphate-sugar backbone spiralling around the outside, and the bases pointing inwards with adenine base pairing to thymine and guanine to cytosine. The specificity of base pairing occurs because adenine and thymine align form two hydrogen bo...
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a709f203344840268c6e1073bb76ea0e
What is the backbone of a DNA double helix made of?
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{ "text": [ "phosphate-sugar" ], "char_spans": [ { "start": [ 78 ], "end": [ 92 ] } ], "token_spans": [ { "start": [ 16 ], "end": [ 18 ] } ] }
[ "phosphate-sugar" ]
SQuAD
Two chains of DNA twist around each other to form a DNA double helix with the phosphate-sugar backbone spiralling around the outside, and the bases pointing inwards with adenine base pairing to thymine and guanine to cytosine. The specificity of base pairing occurs because adenine and thymine align form two hydrogen bo...
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601dc2dab73f4f3b9d5c7a167355121a
What base pairs with thymine?
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{ "text": [ "adenine" ], "char_spans": [ { "start": [ 170 ], "end": [ 176 ] } ], "token_spans": [ { "start": [ 31 ], "end": [ 31 ] } ] }
[ "adenine" ]
SQuAD
Two chains of DNA twist around each other to form a DNA double helix with the phosphate-sugar backbone spiralling around the outside, and the bases pointing inwards with adenine base pairing to thymine and guanine to cytosine. The specificity of base pairing occurs because adenine and thymine align form two hydrogen bo...
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0ae0edc3c6e740ec866e2d533537d41c
What base does guanine pair with?
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{ "text": [ "cytosine" ], "char_spans": [ { "start": [ 217 ], "end": [ 224 ] } ], "token_spans": [ { "start": [ 39 ], "end": [ 39 ] } ] }
[ "cytosine" ]
SQuAD
Two chains of DNA twist around each other to form a DNA double helix with the phosphate-sugar backbone spiralling around the outside, and the bases pointing inwards with adenine base pairing to thymine and guanine to cytosine. The specificity of base pairing occurs because adenine and thymine align form two hydrogen bo...
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b015066a6ee94b72a0575e6af379fc47
What causes the specificity of base pairing?
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{ "text": [ "adenine and thymine align form two hydrogen bonds, whereas cytosine and guanine form three hydrogen bonds" ], "char_spans": [ { "start": [ 274 ], "end": [ 378 ] } ], "token_spans": [ { "start": [ 48 ], "end": [ ...
[ "adenine and thymine align form two hydrogen bonds, whereas cytosine and guanine form three hydrogen bonds" ]
SQuAD
Two chains of DNA twist around each other to form a DNA double helix with the phosphate-sugar backbone spiralling around the outside, and the bases pointing inwards with adenine base pairing to thymine and guanine to cytosine. The specificity of base pairing occurs because adenine and thymine align form two hydrogen bo...
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f2e1f6e7f5c6417da085b12ca1ed3552
Due to the cause of the specificity of base pairing, what must be true of the two strands in a double helix?
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{ "text": [ "The two strands in a double helix must therefore be complementary" ], "char_spans": [ { "start": [ 381 ], "end": [ 445 ] } ], "token_spans": [ { "start": [ 66 ], "end": [ 76 ] } ] }
[ "The two strands in a double helix must therefore be complementary" ]
SQuAD
Due to the chemical composition of the pentose residues of the bases, DNA strands have directionality. One end of a DNA polymer contains an exposed hydroxyl group on the deoxyribose; this is known as the 3' end of the molecule. The other end contains an exposed phosphate group; this is the 5' end. The two strands of a ...
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e912f85b9f2e4f209740d66c763f40a3
What causes the directionality of DNA strands?
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{ "text": [ "the chemical composition of the pentose residues of the bases" ], "char_spans": [ { "start": [ 7 ], "end": [ 67 ] } ], "token_spans": [ { "start": [ 2 ], "end": [ 11 ] } ] }
[ "the chemical composition of the pentose residues of the bases" ]
SQuAD
Due to the chemical composition of the pentose residues of the bases, DNA strands have directionality. One end of a DNA polymer contains an exposed hydroxyl group on the deoxyribose; this is known as the 3' end of the molecule. The other end contains an exposed phosphate group; this is the 5' end. The two strands of a ...
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e7e64d3431af404d92e94e6175f7ad13
What is known as the 3' end?
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{ "text": [ "an exposed hydroxyl group on the deoxyribose" ], "char_spans": [ { "start": [ 137 ], "end": [ 180 ] } ], "token_spans": [ { "start": [ 25 ], "end": [ 31 ] } ] }
[ "an exposed hydroxyl group on the deoxyribose" ]
SQuAD
Due to the chemical composition of the pentose residues of the bases, DNA strands have directionality. One end of a DNA polymer contains an exposed hydroxyl group on the deoxyribose; this is known as the 3' end of the molecule. The other end contains an exposed phosphate group; this is the 5' end. The two strands of a ...
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5b4906d6d8cc4b0ead49cd9f6c1dced3
What is known as the 5' end?
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{ "text": [ "an exposed phosphate group" ], "char_spans": [ { "start": [ 251 ], "end": [ 276 ] } ], "token_spans": [ { "start": [ 49 ], "end": [ 52 ] } ] }
[ "an exposed phosphate group" ]
SQuAD
Due to the chemical composition of the pentose residues of the bases, DNA strands have directionality. One end of a DNA polymer contains an exposed hydroxyl group on the deoxyribose; this is known as the 3' end of the molecule. The other end contains an exposed phosphate group; this is the 5' end. The two strands of a ...
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ba7065592617415c873d0ec40dfc84bb
What type of synthesis occurs in the 5'→3' direction?
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{ "text": [ "Nucleic acid synthesis" ], "char_spans": [ { "start": [ 361 ], "end": [ 382 ] } ], "token_spans": [ { "start": [ 74 ], "end": [ 76 ] } ] }
[ "Nucleic acid synthesis" ]
SQuAD
Many prokaryotic genes are organized into operons, with multiple protein-coding sequences that are transcribed as a unit. The products of operon genes typically have related functions and are involved in the same regulatory network.:7.3
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3f46a244665b45e9bc6cb5083698d4c2
What are most prokaryotic genes organized into?
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{ "text": [ "operons" ], "char_spans": [ { "start": [ 42 ], "end": [ 48 ] } ], "token_spans": [ { "start": [ 6 ], "end": [ 6 ] } ] }
[ "operons" ]
SQuAD
Many prokaryotic genes are organized into operons, with multiple protein-coding sequences that are transcribed as a unit. The products of operon genes typically have related functions and are involved in the same regulatory network.:7.3
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e299552b286a48c5818a5b350abcf8aa
What are multiple protein coding sequences transcribed as?
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{ "text": [ "a unit" ], "char_spans": [ { "start": [ 114 ], "end": [ 119 ] } ], "token_spans": [ { "start": [ 18 ], "end": [ 19 ] } ] }
[ "a unit" ]
SQuAD
Many prokaryotic genes are organized into operons, with multiple protein-coding sequences that are transcribed as a unit. The products of operon genes typically have related functions and are involved in the same regulatory network.:7.3
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407a0a11208f4fb69528c16ddb0981a9
What sort of functions do the products of operon genes typically have?
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{ "text": [ "related functions" ], "char_spans": [ { "start": [ 166 ], "end": [ 182 ] } ], "token_spans": [ { "start": [ 28 ], "end": [ 29 ] } ] }
[ "related functions" ]
SQuAD
Many prokaryotic genes are organized into operons, with multiple protein-coding sequences that are transcribed as a unit. The products of operon genes typically have related functions and are involved in the same regulatory network.:7.3
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35d514f238794c98a8cbc30c9c3b3fa4
What type of coding sequences do prokaryotic genes typically have?
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{ "text": [ "multiple protein-coding sequences" ], "char_spans": [ { "start": [ 56 ], "end": [ 88 ] } ], "token_spans": [ { "start": [ 9 ], "end": [ 13 ] } ] }
[ "multiple protein-coding sequences" ]
SQuAD
Austrian-born Adolf Hitler had a lifelong romantic fascination with the Alps and by the 1930s established a home in the Obersalzberg region outside of Berchtesgaden. His first visit to the area was in 1923 and he maintained a strong tie there until the end of his life. At the end of World War II the US Army occupied Ob...
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ee122cd01eac417685c7d2a842cad7f9
Where was Adolf Hitler born?
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{ "text": [ "Austrian" ], "char_spans": [ { "start": [ 0 ], "end": [ 7 ] } ], "token_spans": [ { "start": [ 0 ], "end": [ 0 ] } ] }
[ "Austrian" ]
SQuAD
Austrian-born Adolf Hitler had a lifelong romantic fascination with the Alps and by the 1930s established a home in the Obersalzberg region outside of Berchtesgaden. His first visit to the area was in 1923 and he maintained a strong tie there until the end of his life. At the end of World War II the US Army occupied Ob...
{ "tokens": [ "Austrian", "-", "born", "Adolf", "Hitler", "had", "a", "lifelong", "romantic", "fascination", "with", "the", "Alps", "and", "by", "the", "1930s", "established", "a", "home", "in", "the", "Obersalzberg", "reg...
d5b1a7d7efbe4eaba2be082600391651
What did Adolf Hitler have a lifelong romantic fascination with?
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{ "text": [ "the Alps" ], "char_spans": [ { "start": [ 68 ], "end": [ 75 ] } ], "token_spans": [ { "start": [ 11 ], "end": [ 12 ] } ] }
[ "the Alps" ]
SQuAD
Austrian-born Adolf Hitler had a lifelong romantic fascination with the Alps and by the 1930s established a home in the Obersalzberg region outside of Berchtesgaden. His first visit to the area was in 1923 and he maintained a strong tie there until the end of his life. At the end of World War II the US Army occupied Ob...
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315134c739084955bc2379278c4fa544
Where did Adolf Hitler establish a home in the 1930s?
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{ "text": [ "the Obersalzberg region" ], "char_spans": [ { "start": [ 116 ], "end": [ 138 ] } ], "token_spans": [ { "start": [ 21 ], "end": [ 23 ] } ] }
[ "the Obersalzberg region" ]
SQuAD
Austrian-born Adolf Hitler had a lifelong romantic fascination with the Alps and by the 1930s established a home in the Obersalzberg region outside of Berchtesgaden. His first visit to the area was in 1923 and he maintained a strong tie there until the end of his life. At the end of World War II the US Army occupied Ob...
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8305f500d970446abc5b5593085272dc
When was Adolf Hitlers first visit to the Alps?
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{ "text": [ "1923" ], "char_spans": [ { "start": [ 201 ], "end": [ 204 ] } ], "token_spans": [ { "start": [ 36 ], "end": [ 36 ] } ] }
[ "1923" ]
SQuAD
The expression of genes encoded in DNA begins by transcribing the gene into RNA, a second type of nucleic acid that is very similar to DNA, but whose monomers contain the sugar ribose rather than deoxyribose. RNA also contains the base uracil in place of thymine. RNA molecules are less stable than DNA and are typically...
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bef61fc37ee140ccb0e3e1a1d634b458
How does the expression of genes encoded in DNA begin?
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{ "text": [ "by transcribing the gene into RNA" ], "char_spans": [ { "start": [ 46 ], "end": [ 78 ] } ], "token_spans": [ { "start": [ 8 ], "end": [ 13 ] } ] }
[ "by transcribing the gene into RNA" ]
SQuAD
The expression of genes encoded in DNA begins by transcribing the gene into RNA, a second type of nucleic acid that is very similar to DNA, but whose monomers contain the sugar ribose rather than deoxyribose. RNA also contains the base uracil in place of thymine. RNA molecules are less stable than DNA and are typically...
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b9e33ec17e8e4d229d156f6f578c1941
What is RNA?
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{ "text": [ "a second type of nucleic acid that is very similar to DNA" ], "char_spans": [ { "start": [ 81 ], "end": [ 137 ] } ], "token_spans": [ { "start": [ 15 ], "end": [ 26 ] } ] }
[ "a second type of nucleic acid that is very similar to DNA" ]
SQuAD
The expression of genes encoded in DNA begins by transcribing the gene into RNA, a second type of nucleic acid that is very similar to DNA, but whose monomers contain the sugar ribose rather than deoxyribose. RNA also contains the base uracil in place of thymine. RNA molecules are less stable than DNA and are typically...
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b5bee82ac3ec48edab5301504c7f142e
What base does RNA have in place of thymine?
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{ "text": [ "the base uracil" ], "char_spans": [ { "start": [ 227 ], "end": [ 241 ] } ], "token_spans": [ { "start": [ 42 ], "end": [ 44 ] } ] }
[ "the base uracil" ]
SQuAD
The expression of genes encoded in DNA begins by transcribing the gene into RNA, a second type of nucleic acid that is very similar to DNA, but whose monomers contain the sugar ribose rather than deoxyribose. RNA also contains the base uracil in place of thymine. RNA molecules are less stable than DNA and are typically...
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7da4d78dddf3431ebe1430b8a7dfdf49
What are codons?
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{ "text": [ "a series of three-nucleotide sequences" ], "char_spans": [ { "start": [ 381 ], "end": [ 418 ] } ], "token_spans": [ { "start": [ 71 ], "end": [ 77 ] } ] }
[ "a series of three-nucleotide sequences" ]
SQuAD
The expression of genes encoded in DNA begins by transcribing the gene into RNA, a second type of nucleic acid that is very similar to DNA, but whose monomers contain the sugar ribose rather than deoxyribose. RNA also contains the base uracil in place of thymine. RNA molecules are less stable than DNA and are typically...
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6b66c1a26b7b42e3a23c38d404410a84
What specifies the correspondence between codons and amino acids during protein translation?
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{ "text": [ "The genetic code" ], "char_spans": [ { "start": [ 489 ], "end": [ 504 ] } ], "token_spans": [ { "start": [ 95 ], "end": [ 97 ] } ] }
[ "The genetic code" ]
SQuAD
Prokaryotes (bacteria and archaea) typically store their genomes on a single large, circular chromosome. Similarly, some eukaryotic organelles contain a remnant circular chromosome with a small number of genes.:14.4 Prokaryotes sometimes supplement their chromosome with additional small circles of DNA called plasmids, ...
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84d382a69a7945069e3c3bd3b7696d37
What are prokaryotes?
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{ "text": [ "bacteria and archaea" ], "char_spans": [ { "start": [ 13 ], "end": [ 32 ] } ], "token_spans": [ { "start": [ 2 ], "end": [ 4 ] } ] }
[ "bacteria and archaea" ]
SQuAD
Prokaryotes (bacteria and archaea) typically store their genomes on a single large, circular chromosome. Similarly, some eukaryotic organelles contain a remnant circular chromosome with a small number of genes.:14.4 Prokaryotes sometimes supplement their chromosome with additional small circles of DNA called plasmids, ...
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a652c1e21a6849fc88a20a10fecc1fb7
How do prokaryotes store their genomes?
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{ "text": [ "on a single large, circular chromosome" ], "char_spans": [ { "start": [ 65 ], "end": [ 102 ] } ], "token_spans": [ { "start": [ 10 ], "end": [ 16 ] } ] }
[ "on a single large, circular chromosome" ]
SQuAD
Prokaryotes (bacteria and archaea) typically store their genomes on a single large, circular chromosome. Similarly, some eukaryotic organelles contain a remnant circular chromosome with a small number of genes.:14.4 Prokaryotes sometimes supplement their chromosome with additional small circles of DNA called plasmids, ...
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e19139c1640b45c2a54f75a86b4509dc
Small circles of DNA that encode only a few genes and are transferable between individuals are called what?
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{ "text": [ "plasmids" ], "char_spans": [ { "start": [ 310 ], "end": [ 317 ] } ], "token_spans": [ { "start": [ 46 ], "end": [ 46 ] } ] }
[ "plasmids" ]
SQuAD
Prokaryotes (bacteria and archaea) typically store their genomes on a single large, circular chromosome. Similarly, some eukaryotic organelles contain a remnant circular chromosome with a small number of genes.:14.4 Prokaryotes sometimes supplement their chromosome with additional small circles of DNA called plasmids, ...
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ec3de2e4a5d14723b6b3091c3ce2906c
What allows genes for antibiotic resistance to be passed between individual cells?
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{ "text": [ "horizontal gene transfer" ], "char_spans": [ { "start": [ 572 ], "end": [ 595 ] } ], "token_spans": [ { "start": [ 90 ], "end": [ 92 ] } ] }
[ "horizontal gene transfer" ]
SQuAD
Firstly, flanking the open reading frame, all genes contain a regulatory sequence that is required for their expression. In order to be expressed, genes require a promoter sequence. The promoter is recognized and bound by transcription factors and RNA polymerase to initiate transcription.:7.1 A gene can have more than ...
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9246631e84ba49878c6cbde3fc300746
What do all genes contain that is required for their expression?
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{ "text": [ "a regulatory sequence" ], "char_spans": [ { "start": [ 60 ], "end": [ 80 ] } ], "token_spans": [ { "start": [ 11 ], "end": [ 13 ] } ] }
[ "a regulatory sequence" ]
SQuAD
Firstly, flanking the open reading frame, all genes contain a regulatory sequence that is required for their expression. In order to be expressed, genes require a promoter sequence. The promoter is recognized and bound by transcription factors and RNA polymerase to initiate transcription.:7.1 A gene can have more than ...
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fdbd1d636cc14a2ab4c369ae989cb3ca
How is a promoter sequence recognized?
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{ "text": [ "by transcription factors and RNA polymerase" ], "char_spans": [ { "start": [ 219 ], "end": [ 261 ] } ], "token_spans": [ { "start": [ 39 ], "end": [ 44 ] } ] }
[ "by transcription factors and RNA polymerase" ]
SQuAD
Firstly, flanking the open reading frame, all genes contain a regulatory sequence that is required for their expression. In order to be expressed, genes require a promoter sequence. The promoter is recognized and bound by transcription factors and RNA polymerase to initiate transcription.:7.1 A gene can have more than ...
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00c325bba80d42e0bc06da501e9f4b4b
What results when genes have more than one promoter?
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{ "text": [ "messenger RNAs (mRNA) that differ in how far they extend in the 5' end" ], "char_spans": [ { "start": [ 347 ], "end": [ 416 ] } ], "token_spans": [ { "start": [ 59 ], "end": [ 75 ] } ] }
[ "messenger RNAs (mRNA) that differ in how far they extend in the 5' end" ]
SQuAD
Firstly, flanking the open reading frame, all genes contain a regulatory sequence that is required for their expression. In order to be expressed, genes require a promoter sequence. The promoter is recognized and bound by transcription factors and RNA polymerase to initiate transcription.:7.1 A gene can have more than ...
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d92f153546df4b36bc5ac689d8854d9b
What does a "strong" promoter sequence do?
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{ "text": [ "bind the transcription machinery well" ], "char_spans": [ { "start": [ 534 ], "end": [ 570 ] } ], "token_spans": [ { "start": [ 95 ], "end": [ 99 ] } ] }
[ "bind the transcription machinery well" ]
SQuAD
Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, e...
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3a45e3b52ecd468693983d28ae593850
How do regulatory regions act?
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{ "text": [ "by binding to transcription factors" ], "char_spans": [ { "start": [ 123 ], "end": [ 157 ] } ], "token_spans": [ { "start": [ 20 ], "end": [ 24 ] } ] }
[ "by binding to transcription factors" ]
SQuAD
Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, e...
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66409a5b9e6941e7b68204fd37b07f70
What happens when a regulatory region binds to transcription factors?
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{ "text": [ "the DNA to loop" ], "char_spans": [ { "start": [ 176 ], "end": [ 190 ] } ], "token_spans": [ { "start": [ 28 ], "end": [ 31 ] } ] }
[ "the DNA to loop" ]
SQuAD
Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, e...
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5f183ab0b5484ff5bce299833ba1582f
How do enhancers increase transcription?
{ "tokens": [ "How", "do", "enhancers", "increase", "transcription", "?" ], "offsets": [ 0, 4, 7, 17, 26, 39 ] }
{ "text": [ "by binding an activator protein" ], "char_spans": [ { "start": [ 352 ], "end": [ 382 ] } ], "token_spans": [ { "start": [ 58 ], "end": [ 62 ] } ] }
[ "by binding an activator protein" ]
SQuAD
Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, e...
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a39ee9be34d9465eb274340d5b3153ff
What happens after an enhancer binds an activator protein?
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{ "text": [ "helps to recruit the RNA polymerase to the promoter" ], "char_spans": [ { "start": [ 395 ], "end": [ 445 ] } ], "token_spans": [ { "start": [ 65 ], "end": [ 73 ] } ] }
[ "helps to recruit the RNA polymerase to the promoter" ]
SQuAD
Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, e...
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f07e9a67840d4d88bc0d616bed6039f2
What causes DNA to be less available for RNA polymerase?
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{ "text": [ "silencers bind repressor proteins" ], "char_spans": [ { "start": [ 459 ], "end": [ 491 ] } ], "token_spans": [ { "start": [ 76 ], "end": [ 79 ] } ] }
[ "silencers bind repressor proteins" ]
SQuAD
Defining exactly what section of a DNA sequence comprises a gene is difficult. Regulatory regions of a gene such as enhancers do not necessarily have to be close to the coding sequence on the linear molecule because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity. Simila...
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ed955f3bca6c49049dee7ac6c08be119
What is an example of a regulatory region of a gene that does not have to close to the coding sequence?
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{ "text": [ "enhancers" ], "char_spans": [ { "start": [ 116 ], "end": [ 124 ] } ], "token_spans": [ { "start": [ 21 ], "end": [ 21 ] } ] }
[ "enhancers" ]
SQuAD
Defining exactly what section of a DNA sequence comprises a gene is difficult. Regulatory regions of a gene such as enhancers do not necessarily have to be close to the coding sequence on the linear molecule because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity. Simila...
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e01bd78d67a84857910f113298a4b2d5
Why do some regulatory regions of a gene not have to be close to the coding sequence?
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{ "text": [ "because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity" ], "char_spans": [ { "start": [ 208 ], "end": [ 311 ] } ], "token_spans": [ { "start": [ 37 ], "end": [ ...
[ "because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity" ]
SQuAD
Defining exactly what section of a DNA sequence comprises a gene is difficult. Regulatory regions of a gene such as enhancers do not necessarily have to be close to the coding sequence on the linear molecule because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity. Simila...
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0604e0b24e9d4990bc310988bbad3839
What part of a gene can be much larger than its exons?
{ "tokens": [ "What", "part", "of", "a", "gene", "can", "be", "much", "larger", "than", "its", "exons", "?" ], "offsets": [ 0, 5, 10, 13, 15, 20, 24, 27, 32, 39, 44, 48, 53 ] }
{ "text": [ "a gene's introns" ], "char_spans": [ { "start": [ 325 ], "end": [ 340 ] } ], "token_spans": [ { "start": [ 58 ], "end": [ 61 ] } ] }
[ "a gene's introns" ]
SQuAD
Defining exactly what section of a DNA sequence comprises a gene is difficult. Regulatory regions of a gene such as enhancers do not necessarily have to be close to the coding sequence on the linear molecule because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity. Simila...
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ffca54449a5245d5b41137840062a54b
How do regulatory regions on different chromosomes operate in order to allow regions on different chromosomes to come into contact with one another?
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{ "text": [ "in trans" ], "char_spans": [ { "start": [ 454 ], "end": [ 461 ] } ], "token_spans": [ { "start": [ 81 ], "end": [ 82 ] } ] }
[ "in trans" ]
SQuAD
Defining exactly what section of a DNA sequence comprises a gene is difficult. Regulatory regions of a gene such as enhancers do not necessarily have to be close to the coding sequence on the linear molecule because the intervening DNA can be looped out to bring the gene and its regulatory region into proximity. Simila...
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d0a02ab9cede4ccf900f1cfae86b8981
Where can regulatory regions be found?
{ "tokens": [ "Where", "can", "regulatory", "regions", "be", "found", "?" ], "offsets": [ 0, 6, 10, 21, 29, 32, 37 ] }
{ "text": [ "different chromosomes" ], "char_spans": [ { "start": [ 420 ], "end": [ 440 ] } ], "token_spans": [ { "start": [ 77 ], "end": [ 78 ] } ] }
[ "different chromosomes" ]
SQuAD
By 1940 the Third Reich had occupied many of the Alpine countries. Austria underwent a political coup that made it part of the Third Reich; France had been invaded and Italy was a fascist regime. Switzerland was the only country to luckily avoid invasion. The Swiss Confederate mobilized its troops—the country follows t...
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1ad506b3eebd4e9faf3d31fb71d7e23b
By 1940 who occupied many of the Alpine countries?
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{ "text": [ "the Third Reich" ], "char_spans": [ { "start": [ 8 ], "end": [ 22 ] } ], "token_spans": [ { "start": [ 2 ], "end": [ 4 ] } ] }
[ "the Third Reich" ]
SQuAD
By 1940 the Third Reich had occupied many of the Alpine countries. Austria underwent a political coup that made it part of the Third Reich; France had been invaded and Italy was a fascist regime. Switzerland was the only country to luckily avoid invasion. The Swiss Confederate mobilized its troops—the country follows t...
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b4f386fe2893474eaed44e02f58c1840
What country underwent a political coup that made it part of the Third Reich?
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{ "text": [ "Austria" ], "char_spans": [ { "start": [ 67 ], "end": [ 73 ] } ], "token_spans": [ { "start": [ 13 ], "end": [ 13 ] } ] }
[ "Austria" ]
SQuAD
By 1940 the Third Reich had occupied many of the Alpine countries. Austria underwent a political coup that made it part of the Third Reich; France had been invaded and Italy was a fascist regime. Switzerland was the only country to luckily avoid invasion. The Swiss Confederate mobilized its troops—the country follows t...
{ "tokens": [ "By", "1940", "the", "Third", "Reich", "had", "occupied", "many", "of", "the", "Alpine", "countries", ".", "Austria", "underwent", "a", "political", "coup", "that", "made", "it", "part", "of", "the", "Thi...
e8cd4c7643f44556badcebfb358ba42a
What was the only country that avoided invasion from the Third Reich?
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{ "text": [ "Switzerland" ], "char_spans": [ { "start": [ 196 ], "end": [ 206 ] } ], "token_spans": [ { "start": [ 38 ], "end": [ 38 ] } ] }
[ "Switzerland" ]
SQuAD
By 1940 the Third Reich had occupied many of the Alpine countries. Austria underwent a political coup that made it part of the Third Reich; France had been invaded and Italy was a fascist regime. Switzerland was the only country to luckily avoid invasion. The Swiss Confederate mobilized its troops—the country follows t...
{ "tokens": [ "By", "1940", "the", "Third", "Reich", "had", "occupied", "many", "of", "the", "Alpine", "countries", ".", "Austria", "underwent", "a", "political", "coup", "that", "made", "it", "part", "of", "the", "Thi...
2f3617f51483433ba1ed0b9e5c21cc78
Who wired the infrastructure leading into Switzerland?
{ "tokens": [ "Who", "wired", "the", "infrastructure", "leading", "into", "Switzerland", "?" ], "offsets": [ 0, 4, 10, 14, 29, 37, 42, 53 ] }
{ "text": [ "The Swiss commanders" ], "char_spans": [ { "start": [ 468 ], "end": [ 487 ] } ], "token_spans": [ { "start": [ 85 ], "end": [ 87 ] } ] }
[ "The Swiss commanders" ]
SQuAD
Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.
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d46be3de9d1c44ebbcbe2bbe8a87fef6
What model did early work in molecular genetics suggest?
{ "tokens": [ "What", "model", "did", "early", "work", "in", "molecular", "genetics", "suggest", "?" ], "offsets": [ 0, 5, 11, 15, 21, 26, 29, 39, 48, 55 ] }
{ "text": [ "the model that one gene makes one protein." ], "char_spans": [ { "start": [ 43 ], "end": [ 84 ] } ], "token_spans": [ { "start": [ 6 ], "end": [ 14 ] } ] }
[ "the model that one gene makes one protein." ]
SQuAD
Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.
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f2f70219df834396bbeba806239bcac5
What discovery caused the model that one gene makes one protein to be refined?
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{ "text": [ "the discovery of genes that can encode multiple proteins" ], "char_spans": [ { "start": [ 120 ], "end": [ 175 ] } ], "token_spans": [ { "start": [ 21 ], "end": [ 29 ] } ] }
[ "the discovery of genes that can encode multiple proteins" ]
SQuAD
Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.
{ "tokens": [ "Early", "work", "in", "molecular", "genetics", "suggested", "the", "model", "that", "one", "gene", "makes", "one", "protein", ".", "This", "model", "has", "been", "refined", "since", "the", "discovery", "of"...
d719c8f6731846ec9cb69e8039624571
How do genes encode multiple proteins?
{ "tokens": [ "How", "do", "genes", "encode", "multiple", "proteins", "?" ], "offsets": [ 0, 4, 7, 13, 20, 29, 37 ] }
{ "text": [ "by alternative splicing and coding sequences" ], "char_spans": [ { "start": [ 177 ], "end": [ 220 ] } ], "token_spans": [ { "start": [ 30 ], "end": [ 35 ] } ] }
[ "by alternative splicing and coding sequences" ]
SQuAD
Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.
{ "tokens": [ "Early", "work", "in", "molecular", "genetics", "suggested", "the", "model", "that", "one", "gene", "makes", "one", "protein", ".", "This", "model", "has", "been", "refined", "since", "the", "discovery", "of"...
384b66b51fc7487f9ac742bf86ac56d4
How are alternative splicing and coding sequences distributed?
{ "tokens": [ "How", "are", "alternative", "splicing", "and", "coding", "sequences", "distributed", "?" ], "offsets": [ 0, 4, 8, 20, 29, 33, 40, 50, 61 ] }
{ "text": [ "split in short section across the genome" ], "char_spans": [ { "start": [ 222 ], "end": [ 261 ] } ], "token_spans": [ { "start": [ 36 ], "end": [ 42 ] } ] }
[ "split in short section across the genome" ]
SQuAD
Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.
{ "tokens": [ "Early", "work", "in", "molecular", "genetics", "suggested", "the", "model", "that", "one", "gene", "makes", "one", "protein", ".", "This", "model", "has", "been", "refined", "since", "the", "discovery", "of"...
7a2d64a7b58041978100f252dbb1b019
In order for a gene to encode multiple proteins, how must its mRNAs be arranged?
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{ "text": [ "concatenated by trans-splicing." ], "char_spans": [ { "start": [ 279 ], "end": [ 309 ] } ], "token_spans": [ { "start": [ 46 ], "end": [ 51 ] } ] }
[ "concatenated by trans-splicing." ]
SQuAD
Organisms inherit their genes from their parents. Asexual organisms simply inherit a complete copy of their parent's genome. Sexual organisms have two copies of each chromosome because they inherit one complete set from each parent.:1
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08cd5910ef0f412ba0d66538e35742e6
Where do organisms inherit their genes from?
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{ "text": [ "from their parents" ], "char_spans": [ { "start": [ 30 ], "end": [ 47 ] } ], "token_spans": [ { "start": [ 4 ], "end": [ 6 ] } ] }
[ "from their parents" ]
SQuAD
Organisms inherit their genes from their parents. Asexual organisms simply inherit a complete copy of their parent's genome. Sexual organisms have two copies of each chromosome because they inherit one complete set from each parent.:1
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dc270ca313ac495f9bb8fc25725012b2
How much of an asexual organism's genome is inherited from its parents?
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{ "text": [ "a complete copy" ], "char_spans": [ { "start": [ 83 ], "end": [ 97 ] } ], "token_spans": [ { "start": [ 12 ], "end": [ 14 ] } ] }
[ "a complete copy" ]
SQuAD
Organisms inherit their genes from their parents. Asexual organisms simply inherit a complete copy of their parent's genome. Sexual organisms have two copies of each chromosome because they inherit one complete set from each parent.:1
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0cac85cbd9aa4673aa08f8133711f683
How many copies of each chromosome does a sexual organism have?
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{ "text": [ "two copies of each chromosome" ], "char_spans": [ { "start": [ 147 ], "end": [ 175 ] } ], "token_spans": [ { "start": [ 24 ], "end": [ 28 ] } ] }
[ "two copies of each chromosome" ]
SQuAD
Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC) for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only one symbol (alth...
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c9147c58045c477eaba38c81e36755b3
What committee has established gene nomenclature for every known human gene?
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{ "text": [ "HUGO Gene Nomenclature Committee (HGNC)" ], "char_spans": [ { "start": [ 46 ], "end": [ 84 ] } ], "token_spans": [ { "start": [ 7 ], "end": [ 13 ] } ] }
[ "HUGO Gene Nomenclature Committee (HGNC)" ]
SQuAD
Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC) for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only one symbol (alth...
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b92b93b70702461fbcc49d3f99881453
How can the gene nomenclature be accessed?
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{ "text": [ "through a database maintained by HGNC" ], "char_spans": [ { "start": [ 209 ], "end": [ 245 ] } ], "token_spans": [ { "start": [ 40 ], "end": [ 45 ] } ] }
[ "through a database maintained by HGNC" ]
SQuAD
Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC) for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only one symbol (alth...
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037b42b752fa4360b22291f145969cd6
How many symbols does each gene have?
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{ "text": [ "only one" ], "char_spans": [ { "start": [ 299 ], "end": [ 306 ] } ], "token_spans": [ { "start": [ 58 ], "end": [ 59 ] } ] }
[ "only one" ]
SQuAD
Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC) for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only one symbol (alth...
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9353de8c3ac04a10a36118dc9a71c19c
With what is it preferred that symbols are kept consistent with?
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{ "text": [ "homologs in other species" ], "char_spans": [ { "start": [ 445 ], "end": [ 469 ] } ], "token_spans": [ { "start": [ 83 ], "end": [ 86 ] } ] }
[ "homologs in other species" ]
SQuAD
Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC) for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only one symbol (alth...
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5d4330014a0140349289569a55b78579
What type of model does the mouse play a role for?
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{ "text": [ "common model" ], "char_spans": [ { "start": [ 516 ], "end": [ 527 ] } ], "token_spans": [ { "start": [ 97 ], "end": [ 98 ] } ] }
[ "common model" ]
SQuAD
In all organisms, two steps are required to read the information encoded in a gene's DNA and produce the protein it specifies. First, the gene's DNA is transcribed to messenger RNA (mRNA).:6.1 Second, that mRNA is translated to protein.:6.2 RNA-coding genes must still go through the first step, but are not translated i...
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f79aea9b6cbf46a980d057f93eaa7159
How many steps are required to read the information encoded in a gene's DNA and produce the specified protein?
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{ "text": [ "two steps are required" ], "char_spans": [ { "start": [ 18 ], "end": [ 39 ] } ], "token_spans": [ { "start": [ 4 ], "end": [ 7 ] } ] }
[ "two steps are required" ]
SQuAD
In all organisms, two steps are required to read the information encoded in a gene's DNA and produce the protein it specifies. First, the gene's DNA is transcribed to messenger RNA (mRNA).:6.1 Second, that mRNA is translated to protein.:6.2 RNA-coding genes must still go through the first step, but are not translated i...
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ba45be18f53f4eabb317a6becd0ef487
What step must RNA-coding genes still go through?
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{ "text": [ "the first step" ], "char_spans": [ { "start": [ 280 ], "end": [ 293 ] } ], "token_spans": [ { "start": [ 54 ], "end": [ 56 ] } ] }
[ "the first step" ]
SQuAD
In all organisms, two steps are required to read the information encoded in a gene's DNA and produce the protein it specifies. First, the gene's DNA is transcribed to messenger RNA (mRNA).:6.1 Second, that mRNA is translated to protein.:6.2 RNA-coding genes must still go through the first step, but are not translated i...
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0af1236d312a455487504200dbf9cdf2
What is the process of producing a biologically functional molecule of either RNA or protein called?
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{ "text": [ "gene expression" ], "char_spans": [ { "start": [ 428 ], "end": [ 442 ] } ], "token_spans": [ { "start": [ 80 ], "end": [ 81 ] } ] }
[ "gene expression" ]
SQuAD
Guinea-Bissau is a member of the United Nations, African Union, Economic Community of West African States, Organisation of Islamic Cooperation, the Latin Union, Community of Portuguese Language Countries, La Francophonie and the South Atlantic Peace and Cooperation Zone.
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2ffe92de29864b78983c8f2d5a3da7c0
What Islamic organization does Guinea-Bissau belong to?
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{ "text": [ "Organisation of Islamic Cooperation" ], "char_spans": [ { "start": [ 107 ], "end": [ 141 ] } ], "token_spans": [ { "start": [ 21 ], "end": [ 24 ] } ] }
[ "Organisation of Islamic Cooperation" ]
SQuAD
Guinea-Bissau is a member of the United Nations, African Union, Economic Community of West African States, Organisation of Islamic Cooperation, the Latin Union, Community of Portuguese Language Countries, La Francophonie and the South Atlantic Peace and Cooperation Zone.
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423882ea467347bbb9d380c64c6003fe
What Portuguese organization does Guinea-Bissau belong to?
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{ "text": [ "Community of Portuguese Language Countries" ], "char_spans": [ { "start": [ 161 ], "end": [ 202 ] } ], "token_spans": [ { "start": [ 30 ], "end": [ 34 ] } ] }
[ "Community of Portuguese Language Countries" ]
SQuAD
Guinea-Bissau is a member of the United Nations, African Union, Economic Community of West African States, Organisation of Islamic Cooperation, the Latin Union, Community of Portuguese Language Countries, La Francophonie and the South Atlantic Peace and Cooperation Zone.
{ "tokens": [ "Guinea", "-", "Bissau", "is", "a", "member", "of", "the", "United", "Nations", ",", "African", "Union", ",", "Economic", "Community", "of", "West", "African", "States", ",", "Organisation", "of", "Islamic", ...
8b526f238e324230acac703004078a36
What West African organization does Guinea-Bissau belong to?
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{ "text": [ "Economic Community of West African States" ], "char_spans": [ { "start": [ 64 ], "end": [ 104 ] } ], "token_spans": [ { "start": [ 14 ], "end": [ 19 ] } ] }
[ "Economic Community of West African States" ]
SQuAD
Guinea-Bissau is a member of the United Nations, African Union, Economic Community of West African States, Organisation of Islamic Cooperation, the Latin Union, Community of Portuguese Language Countries, La Francophonie and the South Atlantic Peace and Cooperation Zone.
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e30305785e3947d1aa4404a4276a9e5c
What South Atlantic organization does Guinea-Bissau belong to?
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{ "text": [ "South Atlantic Peace and Cooperation Zone" ], "char_spans": [ { "start": [ 229 ], "end": [ 269 ] } ], "token_spans": [ { "start": [ 40 ], "end": [ 45 ] } ] }
[ "South Atlantic Peace and Cooperation Zone" ]
SQuAD
Guinea-Bissau is a member of the United Nations, African Union, Economic Community of West African States, Organisation of Islamic Cooperation, the Latin Union, Community of Portuguese Language Countries, La Francophonie and the South Atlantic Peace and Cooperation Zone.
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bef5259eb1724764911dafff6e4972e2
What Latin organization does Guinea-Bissau belong to?
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{ "text": [ "the Latin Union" ], "char_spans": [ { "start": [ 144 ], "end": [ 158 ] } ], "token_spans": [ { "start": [ 26 ], "end": [ 28 ] } ] }
[ "the Latin Union" ]
SQuAD
The nucleotide sequence of a gene's DNA specifies the amino acid sequence of a protein through the genetic code. Sets of three nucleotides, known as codons, each correspond to a specific amino acid.:6 Additionally, a "start codon", and three "stop codons" indicate the beginning and end of the protein coding region. The...
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a11aefa3486b47a283c724634e923216
What specifies the amino acid sequence of a protein?
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{ "text": [ "The nucleotide sequence of a gene's DNA" ], "char_spans": [ { "start": [ 4 ], "end": [ 38 ] } ], "token_spans": [ { "start": [ 1 ], "end": [ 7 ] } ] }
[ "The nucleotide sequence of a gene's DNA" ]
SQuAD
The nucleotide sequence of a gene's DNA specifies the amino acid sequence of a protein through the genetic code. Sets of three nucleotides, known as codons, each correspond to a specific amino acid.:6 Additionally, a "start codon", and three "stop codons" indicate the beginning and end of the protein coding region. The...
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ef4de9c629a6477b9b09572a0d7191d5
What are sets of three nucleotides known as?
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{ "text": [ "codons" ], "char_spans": [ { "start": [ 149 ], "end": [ 154 ] } ], "token_spans": [ { "start": [ 28 ], "end": [ 28 ] } ] }
[ "codons" ]
SQuAD
The nucleotide sequence of a gene's DNA specifies the amino acid sequence of a protein through the genetic code. Sets of three nucleotides, known as codons, each correspond to a specific amino acid.:6 Additionally, a "start codon", and three "stop codons" indicate the beginning and end of the protein coding region. The...
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9d082e554b714a7a8ba3ce32bdaed4c4
What indicates the beginning and end of the protein coding region?
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{ "text": [ "a \"start codon\", and three \"stop codons\"" ], "char_spans": [ { "start": [ 215 ], "end": [ 254 ] } ], "token_spans": [ { "start": [ 39 ], "end": [ 50 ] } ] }
[ "a \"start codon\", and three \"stop codons\"" ]
SQuAD
The nucleotide sequence of a gene's DNA specifies the amino acid sequence of a protein through the genetic code. Sets of three nucleotides, known as codons, each correspond to a specific amino acid.:6 Additionally, a "start codon", and three "stop codons" indicate the beginning and end of the protein coding region. The...
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7a91f08767724907ac04a722cf9109df
How many possible codons are there?
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{ "text": [ "There are 64 possible codons (four possible nucleotides at each of three positions, hence 43 possible codons)" ], "char_spans": [ { "start": [ 317 ], "end": [ 425 ] } ], "token_spans": [ { "start": [ 62 ], "end": [ ...
[ "There are 64 possible codons (four possible nucleotides at each of three positions, hence 43 possible codons)" ]
SQuAD
A typical protein-coding gene is first copied into RNA as an intermediate in the manufacture of the final protein product.:6.1 In other cases, the RNA molecules are the actual functional products, as in the synthesis of ribosomal RNA and transfer RNA. Some RNAs known as ribozymes are capable of enzymatic function, and ...
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52230d50fcb44881baec2618b9c74d6e
What is first copied into RNA as an intermediate in the manufacture of the final protein product?
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{ "text": [ "A typical protein-coding gene" ], "char_spans": [ { "start": [ 2 ], "end": [ 28 ] } ], "token_spans": [ { "start": [ 1 ], "end": [ 5 ] } ] }
[ "A typical protein-coding gene" ]
SQuAD
A typical protein-coding gene is first copied into RNA as an intermediate in the manufacture of the final protein product.:6.1 In other cases, the RNA molecules are the actual functional products, as in the synthesis of ribosomal RNA and transfer RNA. Some RNAs known as ribozymes are capable of enzymatic function, and ...
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d65e04400e124972b976bdd797535516
In some cases, what are the actual functional products?
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{ "text": [ "the RNA molecules" ], "char_spans": [ { "start": [ 143 ], "end": [ 159 ] } ], "token_spans": [ { "start": [ 26 ], "end": [ 28 ] } ] }
[ "the RNA molecules" ]
SQuAD
A typical protein-coding gene is first copied into RNA as an intermediate in the manufacture of the final protein product.:6.1 In other cases, the RNA molecules are the actual functional products, as in the synthesis of ribosomal RNA and transfer RNA. Some RNAs known as ribozymes are capable of enzymatic function, and ...
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8ef60e4ca0874b5fa6c87a92656c8a82
What sort of synthesis occurs when the RNA molecules are the actual functional products?
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{ "text": [ "the synthesis of ribosomal RNA and transfer RNA" ], "char_spans": [ { "start": [ 203 ], "end": [ 249 ] } ], "token_spans": [ { "start": [ 37 ], "end": [ 44 ] } ] }
[ "the synthesis of ribosomal RNA and transfer RNA" ]
SQuAD
A typical protein-coding gene is first copied into RNA as an intermediate in the manufacture of the final protein product.:6.1 In other cases, the RNA molecules are the actual functional products, as in the synthesis of ribosomal RNA and transfer RNA. Some RNAs known as ribozymes are capable of enzymatic function, and ...
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1cd51ce370704e24a9009a8c312e2139
What sort of function are ribozymes capable of?
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{ "text": [ "enzymatic function" ], "char_spans": [ { "start": [ 296 ], "end": [ 313 ] } ], "token_spans": [ { "start": [ 54 ], "end": [ 55 ] } ] }
[ "enzymatic function" ]
SQuAD
A typical protein-coding gene is first copied into RNA as an intermediate in the manufacture of the final protein product.:6.1 In other cases, the RNA molecules are the actual functional products, as in the synthesis of ribosomal RNA and transfer RNA. Some RNAs known as ribozymes are capable of enzymatic function, and ...
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a0fda52955964913b36ffc1e2d03c3df
What are the DNA sequences from which ribozymes are transcribed known as?
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{ "text": [ "non-coding RNA genes" ], "char_spans": [ { "start": [ 420 ], "end": [ 439 ] } ], "token_spans": [ { "start": [ 76 ], "end": [ 80 ] } ] }
[ "non-coding RNA genes" ]
SQuAD
Early reports of Europeans reaching this area include those of the Venetian Alvise Cadamosto's voyage of 1455, the 1479–1480 voyage by Flemish-French trader Eustache de la Fosse, and Diogo Cão. In the 1480s this Portuguese explorer reached the Congo River and the lands of Bakongo, setting up the foundations of modern A...
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c94fd3d18ab34e4cbcec7491c7ac7a9d
When was Alvise Cadamosto's voyage?
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{ "text": [ "1455" ], "char_spans": [ { "start": [ 105 ], "end": [ 108 ] } ], "token_spans": [ { "start": [ 17 ], "end": [ 17 ] } ] }
[ "1455" ]
SQuAD
Early reports of Europeans reaching this area include those of the Venetian Alvise Cadamosto's voyage of 1455, the 1479–1480 voyage by Flemish-French trader Eustache de la Fosse, and Diogo Cão. In the 1480s this Portuguese explorer reached the Congo River and the lands of Bakongo, setting up the foundations of modern A...
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When was Eustache de la Fosse's voyage?
{ "tokens": [ "When", "was", "Eustache", "de", "la", "Fosse", "'s", "voyage", "?" ], "offsets": [ 0, 5, 9, 18, 21, 24, 29, 32, 38 ] }
{ "text": [ "1479–1480" ], "char_spans": [ { "start": [ 115 ], "end": [ 123 ] } ], "token_spans": [ { "start": [ 20 ], "end": [ 20 ] } ] }
[ "1479–1480" ]
SQuAD
Early reports of Europeans reaching this area include those of the Venetian Alvise Cadamosto's voyage of 1455, the 1479–1480 voyage by Flemish-French trader Eustache de la Fosse, and Diogo Cão. In the 1480s this Portuguese explorer reached the Congo River and the lands of Bakongo, setting up the foundations of modern A...
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What was the name of the Portuguese explorer?
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{ "text": [ "Diogo Cão" ], "char_spans": [ { "start": [ 183 ], "end": [ 191 ] } ], "token_spans": [ { "start": [ 33 ], "end": [ 34 ] } ] }
[ "Diogo Cão" ]
SQuAD
Early reports of Europeans reaching this area include those of the Venetian Alvise Cadamosto's voyage of 1455, the 1479–1480 voyage by Flemish-French trader Eustache de la Fosse, and Diogo Cão. In the 1480s this Portuguese explorer reached the Congo River and the lands of Bakongo, setting up the foundations of modern A...
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What river did Diogo Cao reach in the 1480's?
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{ "text": [ "Congo River" ], "char_spans": [ { "start": [ 244 ], "end": [ 254 ] } ], "token_spans": [ { "start": [ 44 ], "end": [ 45 ] } ] }
[ "Congo River" ]
SQuAD
Early reports of Europeans reaching this area include those of the Venetian Alvise Cadamosto's voyage of 1455, the 1479–1480 voyage by Flemish-French trader Eustache de la Fosse, and Diogo Cão. In the 1480s this Portuguese explorer reached the Congo River and the lands of Bakongo, setting up the foundations of modern A...
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What country is about 4200 km from Guinea-Bissau?
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{ "text": [ "Angola" ], "char_spans": [ { "start": [ 319 ], "end": [ 324 ] } ], "token_spans": [ { "start": [ 58 ], "end": [ 58 ] } ] }
[ "Angola" ]
SQuAD
Transcription produces a single-stranded RNA molecule known as messenger RNA, whose nucleotide sequence is complementary to the DNA from which it was transcribed.:6.1 The mRNA acts as an intermediate between the DNA gene and its final protein product. The gene's DNA is used as a template to generate a complementary mRN...
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What does transcription produce?
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{ "text": [ "a single-stranded RNA molecule known as messenger RNA" ], "char_spans": [ { "start": [ 23 ], "end": [ 75 ] } ], "token_spans": [ { "start": [ 2 ], "end": [ 11 ] } ] }
[ "a single-stranded RNA molecule known as messenger RNA" ]
SQuAD
Transcription produces a single-stranded RNA molecule known as messenger RNA, whose nucleotide sequence is complementary to the DNA from which it was transcribed.:6.1 The mRNA acts as an intermediate between the DNA gene and its final protein product. The gene's DNA is used as a template to generate a complementary mRN...
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What is used as a template to generate a complementary mRNA?
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{ "text": [ "The gene's DNA" ], "char_spans": [ { "start": [ 252 ], "end": [ 265 ] } ], "token_spans": [ { "start": [ 42 ], "end": [ 45 ] } ] }
[ "The gene's DNA" ]
SQuAD
Transcription produces a single-stranded RNA molecule known as messenger RNA, whose nucleotide sequence is complementary to the DNA from which it was transcribed.:6.1 The mRNA acts as an intermediate between the DNA gene and its final protein product. The gene's DNA is used as a template to generate a complementary mRN...
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Why does the mRNA match the sequence of the gene's DNA coding strand?
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{ "text": [ "because it is synthesised as the complement of the template strand" ], "char_spans": [ { "start": [ 385 ], "end": [ 450 ] } ], "token_spans": [ { "start": [ 69 ], "end": [ 79 ] } ] }
[ "because it is synthesised as the complement of the template strand" ]
SQuAD
Transcription produces a single-stranded RNA molecule known as messenger RNA, whose nucleotide sequence is complementary to the DNA from which it was transcribed.:6.1 The mRNA acts as an intermediate between the DNA gene and its final protein product. The gene's DNA is used as a template to generate a complementary mRN...
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What is the enzyme called that performs transcription?
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{ "text": [ "an RNA polymerase" ], "char_spans": [ { "start": [ 500 ], "end": [ 516 ] } ], "token_spans": [ { "start": [ 88 ], "end": [ 90 ] } ] }
[ "an RNA polymerase" ]
SQuAD
According to Mendelian inheritance, variations in an organism's phenotype (observable physical and behavioral characteristics) are due in part to variations in its genotype (particular set of genes). Each gene specifies a particular trait with different sequence of a gene (alleles) giving rise to different phenotypes. ...
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According to Mendelian inheritance, what is part of the cause of variations in an organism's phenotype?
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{ "text": [ "variations in its genotype" ], "char_spans": [ { "start": [ 146 ], "end": [ 171 ] } ], "token_spans": [ { "start": [ 23 ], "end": [ 26 ] } ] }
[ "variations in its genotype" ]
SQuAD
According to Mendelian inheritance, variations in an organism's phenotype (observable physical and behavioral characteristics) are due in part to variations in its genotype (particular set of genes). Each gene specifies a particular trait with different sequence of a gene (alleles) giving rise to different phenotypes. ...
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What sort of characteristics are described by an organism's phenotype?
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{ "text": [ "observable physical and behavioral characteristics" ], "char_spans": [ { "start": [ 75 ], "end": [ 124 ] } ], "token_spans": [ { "start": [ 12 ], "end": [ 16 ] } ] }
[ "observable physical and behavioral characteristics" ]
SQuAD
According to Mendelian inheritance, variations in an organism's phenotype (observable physical and behavioral characteristics) are due in part to variations in its genotype (particular set of genes). Each gene specifies a particular trait with different sequence of a gene (alleles) giving rise to different phenotypes. ...
{ "tokens": [ "According", "to", "Mendelian", "inheritance", ",", "variations", "in", "an", "organism", "'s", "phenotype", "(", "observable", "physical", "and", "behavioral", "characteristics", ")", "are", "due", "in", "part", ...
cbf085453bd14207b5ca134c6745f6c4
What is a genotype?
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{ "text": [ "particular set of genes" ], "char_spans": [ { "start": [ 174 ], "end": [ 196 ] } ], "token_spans": [ { "start": [ 28 ], "end": [ 31 ] } ] }
[ "particular set of genes" ]
SQuAD
According to Mendelian inheritance, variations in an organism's phenotype (observable physical and behavioral characteristics) are due in part to variations in its genotype (particular set of genes). Each gene specifies a particular trait with different sequence of a gene (alleles) giving rise to different phenotypes. ...
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What specifies a particular trait with a different sequence of alleles?
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{ "text": [ "Each gene" ], "char_spans": [ { "start": [ 200 ], "end": [ 208 ] } ], "token_spans": [ { "start": [ 34 ], "end": [ 35 ] } ] }
[ "Each gene" ]
SQuAD
According to Mendelian inheritance, variations in an organism's phenotype (observable physical and behavioral characteristics) are due in part to variations in its genotype (particular set of genes). Each gene specifies a particular trait with different sequence of a gene (alleles) giving rise to different phenotypes. ...
{ "tokens": [ "According", "to", "Mendelian", "inheritance", ",", "variations", "in", "an", "organism", "'s", "phenotype", "(", "observable", "physical", "and", "behavioral", "characteristics", ")", "are", "due", "in", "part", ...
c70d2401088f4ab2b3cb5553bf74033b
How many alleles do most eukaryotic organisms have for each trait?
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{ "text": [ "two alleles for each trait" ], "char_spans": [ { "start": [ 393 ], "end": [ 418 ] } ], "token_spans": [ { "start": [ 69 ], "end": [ 73 ] } ] }
[ "two alleles for each trait" ]
SQuAD
In prokaryotes, transcription occurs in the cytoplasm; for very long transcripts, translation may begin at the 5' end of the RNA while the 3' end is still being transcribed. In eukaryotes, transcription occurs in the nucleus, where the cell's DNA is stored. The RNA molecule produced by the polymerase is known as the pr...
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Where does transcription occur in prokaryotes?
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{ "text": [ "in the cytoplasm" ], "char_spans": [ { "start": [ 37 ], "end": [ 52 ] } ], "token_spans": [ { "start": [ 5 ], "end": [ 7 ] } ] }
[ "in the cytoplasm" ]
SQuAD
In prokaryotes, transcription occurs in the cytoplasm; for very long transcripts, translation may begin at the 5' end of the RNA while the 3' end is still being transcribed. In eukaryotes, transcription occurs in the nucleus, where the cell's DNA is stored. The RNA molecule produced by the polymerase is known as the pr...
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If the transcription is very long, where on the RNA may translation begin?
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{ "text": [ "at the 5' end of the RNA" ], "char_spans": [ { "start": [ 104 ], "end": [ 127 ] } ], "token_spans": [ { "start": [ 17 ], "end": [ 24 ] } ] }
[ "at the 5' end of the RNA" ]
SQuAD
In prokaryotes, transcription occurs in the cytoplasm; for very long transcripts, translation may begin at the 5' end of the RNA while the 3' end is still being transcribed. In eukaryotes, transcription occurs in the nucleus, where the cell's DNA is stored. The RNA molecule produced by the polymerase is known as the pr...
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Where does transcription occur in eukaryotes?
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{ "text": [ "transcription occurs in the nucleus" ], "char_spans": [ { "start": [ 189 ], "end": [ 223 ] } ], "token_spans": [ { "start": [ 38 ], "end": [ 42 ] } ] }
[ "transcription occurs in the nucleus" ]
SQuAD
In prokaryotes, transcription occurs in the cytoplasm; for very long transcripts, translation may begin at the 5' end of the RNA while the 3' end is still being transcribed. In eukaryotes, transcription occurs in the nucleus, where the cell's DNA is stored. The RNA molecule produced by the polymerase is known as the pr...
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Where does a eukaryote store the cell's DNA?
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{ "text": [ "in the nucleus" ], "char_spans": [ { "start": [ 210 ], "end": [ 223 ] } ], "token_spans": [ { "start": [ 40 ], "end": [ 42 ] } ] }
[ "in the nucleus" ]
SQuAD
In prokaryotes, transcription occurs in the cytoplasm; for very long transcripts, translation may begin at the 5' end of the RNA while the 3' end is still being transcribed. In eukaryotes, transcription occurs in the nucleus, where the cell's DNA is stored. The RNA molecule produced by the polymerase is known as the pr...
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What is the RNA molecule produced by the polymerase known as?
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{ "text": [ "the primary transcript" ], "char_spans": [ { "start": [ 314 ], "end": [ 335 ] } ], "token_spans": [ { "start": [ 62 ], "end": [ 64 ] } ] }
[ "the primary transcript" ]
SQuAD
Despite reports of arms entering the country prior to the election and some "disturbances during campaigning," including attacks on government offices by unidentified gunmen, foreign election monitors described the 2005 election overall as "calm and organized".
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What was reported to be entering the country prior to the election?
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{ "text": [ "arms" ], "char_spans": [ { "start": [ 19 ], "end": [ 22 ] } ], "token_spans": [ { "start": [ 3 ], "end": [ 3 ] } ] }
[ "arms" ]
SQuAD
Despite reports of arms entering the country prior to the election and some "disturbances during campaigning," including attacks on government offices by unidentified gunmen, foreign election monitors described the 2005 election overall as "calm and organized".
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What type of "disturbances" were reported during the campaign?
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{ "text": [ "attacks on government offices" ], "char_spans": [ { "start": [ 121 ], "end": [ 149 ] } ], "token_spans": [ { "start": [ 20 ], "end": [ 23 ] } ] }
[ "attacks on government offices" ]
SQuAD
Despite reports of arms entering the country prior to the election and some "disturbances during campaigning," including attacks on government offices by unidentified gunmen, foreign election monitors described the 2005 election overall as "calm and organized".
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How did foreign election monitors describe the election?
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{ "text": [ "\"calm and organized\"" ], "char_spans": [ { "start": [ 240 ], "end": [ 259 ] } ], "token_spans": [ { "start": [ 37 ], "end": [ 41 ] } ] }
[ "\"calm and organized\"" ]
SQuAD
Despite reports of arms entering the country prior to the election and some "disturbances during campaigning," including attacks on government offices by unidentified gunmen, foreign election monitors described the 2005 election overall as "calm and organized".
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What year was the election held?
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{ "text": [ "2005" ], "char_spans": [ { "start": [ 215 ], "end": [ 218 ] } ], "token_spans": [ { "start": [ 33 ], "end": [ 33 ] } ] }
[ "2005" ]
SQuAD
Despite reports of arms entering the country prior to the election and some "disturbances during campaigning," including attacks on government offices by unidentified gunmen, foreign election monitors described the 2005 election overall as "calm and organized".
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Where the election monitors local, or foreign?
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{ "text": [ "foreign" ], "char_spans": [ { "start": [ 175 ], "end": [ 181 ] } ], "token_spans": [ { "start": [ 28 ], "end": [ 28 ] } ] }
[ "foreign" ]
SQuAD
Genes with a most recent common ancestor, and thus a shared evolutionary ancestry, are known as homologs. These genes appear either from gene duplication within an organism's genome, where they are known as paralogous genes, or are the result of divergence of the genes after a speciation event, where they are known as ...
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What are genes with a most recent common ancestor called?
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{ "text": [ "homologs" ], "char_spans": [ { "start": [ 96 ], "end": [ 103 ] } ], "token_spans": [ { "start": [ 18 ], "end": [ 18 ] } ] }
[ "homologs" ]
SQuAD
Genes with a most recent common ancestor, and thus a shared evolutionary ancestry, are known as homologs. These genes appear either from gene duplication within an organism's genome, where they are known as paralogous genes, or are the result of divergence of the genes after a speciation event, where they are known as ...
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ab6db6715bda4393b746cbf470dcf087
What is one reason for homologs to appear?
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{ "text": [ "gene duplication within an organism's genome" ], "char_spans": [ { "start": [ 137 ], "end": [ 180 ] } ], "token_spans": [ { "start": [ 25 ], "end": [ 31 ] } ] }
[ "gene duplication within an organism's genome" ]