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The Blade of the laryngoscope used in intubation of newborn is
The Macintosh blade is the most widely used of the curved laryngoscope blades, while the Miller blade is the most popular style of straight blade. The Miller blades are commonly used for infants.Uncuffed tubes are limited mostly to pediatric patients (in small children, the cricoid cailage, the narrowest poion of the p...
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Uterus develops from-
A i.e. Mullerian duct
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Which of the following poison is associated with the development of Acrodynia?
Acrodynia also known as pink disease is characterised by a generalised pink rash. It is a idiosyncratic hypersensitivity reaction of insidious onset with anorexia, insomnia, sweating, skin rash, photophobia, puffy hands and feet and peeling of skin. It occurs as a result of chronic exposure to mercury and usually in ch...
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All are features of early gastric carcinoma except:
Ans. is 'c' ie Muscularis Propria involvement Early gastric cancer is defined as adenocarcinoma limited to the mucosa and submucosa of the stomach regardless of the lymphonodi status.Approximately 10% of patients with early gastric cancer are found to have lymph node metastasis on presentation.Overall cure rate with ad...
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Schwartz sign is seen in
Ans. is 'a' i.e., Otosclerosis FINDINGS IN OTOSCLEROSISSymptoms of otosclerosiso Hearing loss Bilateral conductive deafness which is painless and progressive with insidious onset. In cochlear otosclerosis sensorineural hearing loss also occur along with conductive deafness,o Paracusis willissii An otosclerotic patient ...
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Both antibody dependent and independent complement pathway converge on which of the following complement component ?
. C3
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Features of lewy body dementia are all except:
Revised criteria for the clinical diagnosis of Lewy body dementia: 1.Fluctuating Cognition 2.Recurrent Visual hallucination 3.REM sleep behaviour disorder 4.Cardinal feature of Parkinsonism (one or more)
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Maltese cross is seen on polarizing microscopy in which of following?
In Polarized light maltese cross appearance is seen in cryptococcus. So-called "Maltese cross formations" on the blood film are essentially diagnostic of babesiosis, since they are not seen in malaria, the primary differential diagnosis. Ref: Brooks G.F., Carroll K.C., Butel J.S., Morse S.A., Mietzneron T.A. (2010). Ch...
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Thinning of cornea occurs in –
Essential pathological changes in keratoconus are thinning and ectasia.
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All is exempted from oral testimony except-
Oral testimony is not required in:- Dying declaration. Deposition of medical witness taken in lower court. Evidence given by a witness in a previous judicial proceedings. Expert opinion expressed in a treatise (ex. book). Report of a certain government scientific experts eg. chemical examiner, assistant chemical exami...
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In optic atrophy, the optic disc appears pale, is index of-
Disappearance of vascularity of the disc causes increase in pallor.
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Trichology is the forensic examination of
Examination of hair(Trichiology) can provide valuable information in crime investigation. forensic trichiology : The first step of forensic identification and comparison of hairs begins with whole mount light microscopy. The hair(s) in question must be identified as to species, race and body (somatic) origin. Human hai...
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Bulb of posterior horn of lateral ventricle is formed by
Bulb of posterior horn is present on medial wall of posterior horn of lateral ventricle and is formed by fibers of forceps major.
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Larvae of which of the following lies parallel to surface of water : September 2007
Ans. A: Anopheles Mosquito larvae have a well-developed head with mouth brushes used for feeding, a large thorax and a segmented abdomen. They have no legs. In contrast to other mosquitoes, Anopheles larvae lack a respiratory siphon and for this reason position themselves so that their body is parallel to the surface o...
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A 2-year-old infant is brought to the emergency room with hemolytic uremic syndrome and thrombocytopenia. Which one of the following bacteria would most likely be isolated from a stool specimen?
Food poisoning with E. coli 0157/H7 causes hemorrhagic colitis; it is often seen after eating beef hamburgers. The same organism also causes a hemorrhagic uremic syndrome. The toxin, called Shiga-like toxin, can be demonstrated in Vero cells, but the cytotoxicity must be neutralized with specific antiserum. With the ex...
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Most impoant investigation for posterior urethral valve: March 2011
Ans. D: Micturating cystogram (MCU) Micturating cystography is mainly done to assess urethra for any outflow obstruction and stress incontinence Also done to demonstrate vesico-ureteric reflux especially in children Radiological signs of urinary tract: Bilateral spider leg pattern: Polycystic kidney Thimble bladder: Ch...
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An infant presents to OPD with signs of heart failure. On examination, there is hypotonia; hepatomegaly, cardiomegaly. ECG shows tall QRS complex and short PR interval. Which enzyme is deficient in this condition?
Hypotonia, hepatomegaly, cardiomegalyare seen in Pompe disease. Acid maltase or Alpha 1,4. Glucosidase is deficient in Pompe disease.
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Essential amino acid amongst the following
Essential amino acids: These are the ones which are not synthesised by the body and must be taken in diet. They include valine, leucine, isoleucine, phenylalanine, threonine, tryptophan, methionine and lysine. For remembering the following formula is used--MATT VIL PHLY.Ref: Textbook of medical biochemistry, MN Chatter...
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Precocious puberty is defined as all of following except
Precocious puberty is menstruation before age of 10 years.
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Spalding sign indicates: March 2003
Ans. C i.e. Dead born child
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A man presented with cut wound over scalp. The best anaesthetic agent for wound repair is:
In clinical practice, a vasoconstrictor, usually epinephrine, is often added to local anesthetics. The vasoconstrictor performs a dual service. By decreasing the rate of absorption, it not only localizes the anesthetic at the desired site, but also allows the rate at which it is destroyed in the body to keep pace with ...
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Thumb print sign in plain x-ray is seen in:
Ans: a (Ischeamic colitis)Ref: Harrison, 17 ed. pg. 1091, 213; Grainger and Allison 5 ed. pg. 889.Thumb printing sign, i.e., bowel wall oedema seen as an early sign in ischaemic colitis. Also seen in: amoebic colitis and ulcerative colitisIschaemic colitis: Most common sites - Watershed areas of colon Splenic flexure (...
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All of the following physiological changes are seen in pregnancy except:
Ans. d. Increased peripheral resistance (Ref: Dutta 6/e p53, 51)During the physiological course of pregnancy, maternal peripheral vascular resistance decreases."Pregnancy is a state of hypervolemia. There is active retention of sodium (900 mmol), potassium (350 mmol) and water."- Dutta 6/e p51Hemodynamic Changes during...
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Submucosal plexus is -
Ans. is 'c' i.e., Meissner's plexusInnervation of GITo The gastrointestinal tract has a nervous system all its own called the enteric nervous system. It lies entirely in the wall of the gut, beginning in the esophagus and extending all the way to the anus. The enteric nervous system is composed mainly of two plexus : -...
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Pelkan spur is seen in –
Pelkan spur is seen in scurvy.
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Most common site of metastasis in Choriocarcinoma is?
ANSWER: (B) LungsREF: Shaw 14th e p- 233Sites of metastasis in choriocarcinomaLungs (80%) > vagina (30%) > pelvis (20%) > liver (10%) > brain (10%)
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Which of the following is true regarding vessels in the umbilical cord :
C. i.e. Two aeries and the left vein;
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Serological pattern observed for Acute Hepatitis B, with active viral replication is:
Hepatitis B virus expresses three antigens, viz. Corresponding antibodies produced on stimulation of immune system are: 1. HBsAg (Australia antigen) - surface antigen - 1st antigen to appear 2. HBcAg - core antigen - Rarely appears alone 3. HBeAg - Marker of infectivity, indicate active viral replication 1. Anti-HBs - ...
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17 yr girl presents with primary amenorrhea. On examination there is absent breast development, however vagina is normal. USG reveals a hypoplastic uterus and bilateral ovaries are not visualised. Diagnosis is
Turner syndrome (45,X) is the most common karyotypic abnormality causing gonadal failure and primary amenorrhea. Amenorrhea is the result of accelerated atresia of the follicles. The fibrotic ovaries are called streak ovaries. Associated stigmata with Turner syndrome include Gonadal Failure Sho stature Webbed neck, Shi...
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Inclusions in oligodendrogliocytes is a feature of aEUR'
Progressive multifocal leukoencephalopathy Progressive multifocal leucoencephalopathy :? . Progressive multifocal leucoencephalopathy is a progressive disorder cause by J.C. virusdeg. . The main cells affected in the disease are oligodendrocytesdeg. . Since oligodendrocytes are concerned with myelination, progressive m...
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Sentinal lymph node for carcinoma penis is know as
Cabana Node ⇒ Superficial injuinal node is the sentinal lymph node for carcinoma penis.
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Placenta pre true are:
Prior surgery on the uterus especially Caesarean section increases the incidence of placenta prae two or three fold.The combination of a prior Caesarean section with an anterior placenta prae is paicularly dangerous (refer pgno:129 sheila textbook of obstetrics 2nd edition)
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What percentage of cold thyroid nodules are malignant
Ans. is 'd' i.e. 10-20%
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All of the following are reasons for cone cut except:
Cone cut: Cause: Cone of radiation not covering the area of interest, not using film holders. Correction: Make sure that the cone is properly centered over the area of interest and the film, both vertically and horizontally. Cause: PID not properly aligned with the periapical film holder. Correction: Position the PID ...
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Which agent is used to prevent synechiae after DCR surgery
Ans. is 'a' i.e., Mitomycin Now, Mitomycin is being increasingly used for this purpose and is proving more usefulMitomycin is an anticancer agent that has shown to decrease scar formation after E.N.T. surgeryIt is an antifibroblastic agent and thus prevents the wound healing and subsequent synechae formation.It is usef...
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Laproscopic procedure patient develops shoulder pain due to
Ans. (c) Sub diaphragmatic migration of gas(Ref: Bailey 26th 100-101)* Shoulder pain after laparoscopy is due to pain referred from diaphragm and due to subdiaphragmatic migration of gas
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All of the following statements about Staphylococcus aureus are true, Except
The most common source of infection is human patients and carriers Animals and inanimate objects being less impoant. Ref: Textbook of Microbiology; Ananthanarayanan and Panicker; 10th Edition; Page No: 205
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Which of the following is not found commonly in Graves disease?
Graves disease is the most common cause of endogenous hypehyroidism. Most common antibody subtype, known as thyroid-stimulating immunoglobulin (TSI) is observed in approximately 90% of patients with Graves disease resulting in hypehyroidism. Thyroid-stimulating immunoglobulin (TSI) is directed mainly against TSH recept...
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Choose the right combination:
Ans. is 'c' i.e., Z.N. staining - Mycobacterium tuberculosisImage description - Z.N. staining of smear showing long slender, beaded, red colored acid fast bacilli with numerous pus cells against blue background.
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Which of the following is NOT the feature of secondary ACTH deficiency?
Clinical feature of secondary ACTH deficiency: Mineralocoicoid secretion is intact. Manifests more insidiously with lack of skin hyperpigmentation. Hypotension is seen with gluco-coicoid deficiency because of loss of control of inhibition of vasopressin. Fatigue, hyponatremia, and hypoglycaemia is also seen
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A young male presented with abdominal pain for the past 2 years. He also complains of weakness in his hands. His hemoblobin level was 8 gm/dL. The most likely diagnosis:
Ans. a. Lead poisoning (Ref: Parikh 6/e p9.22; Reddy 33/e p544, 31st/e p506-508)The most likely diagnosis in a young male who presented with abdominal pain for the past 2 years with complains of weakness in his hands and hemoblobin level of 8 gm/dL is lead poisoning.Lead poisoningMetallic lead and all its salts are poi...
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Investigation of choice for amoebic liver abscess: March 2012
Ans: B i.e. Serum Entamoeba antibodies Diagnosis of amoebic liver disease Analysis of serum for Entamoeba antibodies by immunoassay carries 99% sensitivity and more than 90% specificity, and is more accurate than stool analysis in amoebic liver disease Diagnosis may depend on cyst aspiration revealing the classic ancho...
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Following are true regarding chlorination except –
Contact period of 1 hour is recommended.
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Which is rheumatic ahritis autoantibody -
Answer is anti ccp Rheumatoid ahritis is an autoimmune disease involving complex and still poorly understood interactions of genetic risk factors, environment and the immune system. In atleast 70% of patients the blood contains anti-ccp antibody, which may be produced during inflammation. These antibodies contribute to...
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Fomepizole as a antidote is used in the poisoning of: September 2009 and March 2013 (b, h)
Ans. B: Methyl alcohol Fomepizole or 4-methylpyrazole is indicated for use as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. It may be used alone or in combination with hemodialysis.
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A patients present with dogs bite in the palm, fingers and oozing of blood on the neck regions, belongs to which class of the exposures
(Class III) (231- Park 19th) (243-Park 20th)CLASSIFICATION OF EXPOSURESClass I (Slight risk)Class II (Moderate risk)* Licks on healthy unbroken skin* Consumption of unboiled milk of the suspected animals* Scratches without oozing of bloodLikes on fresh cutsScratches with oozing of bloodAll bites except those on head ne...
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One of the following statements is NOT true:
An Assistant Sessions Judge can award imprisonment for a term exceeding 10 years (Sessions cou is located at district headquaers. It can pass any sentence authorized by law but a sentence of death must be confirmed by the high cou (Sec. 366 CrPC). Assistant Sessions cou can pass any sentence except a sentence of death ...
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Investigation of choice for SCIWORA is
'SCIWORA' is the abbretion of 'spinal cord injury without radiographic abnormality'. MRI is the Investigation of Choice and has normal plain film and CT findings. It tends to occur in the paediatric population and involves upper cervical spinal cord. MRI cervical-dorsal spine Sagitta view of a paediatric patient showin...
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True about simple randomization is-
Park's textbook of preventive and social medicine 23rd edition *With this procedure,the sample is drawn in such a way that each unit has an equal chance of being drawn in the sample.
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Consider the following in a newborn:1, Hea rate of 1102. Slow and Irregular respiratory effo3. Flaccid muscle tone4. No reflex irritability5. Blue colorWhat is the Apgar score in this case?
For blue color point 0, for hea rate more than 110 points 2, for flaccid muscle tone point 0, for Slow and irregular respiratory movements point 1. For APGAR score, Refer page no 535 of Textbook of obstetrics, Sheila Balakrishnan, 2 nd edition.
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Endoplasmic reticulum is not involved in ?
Ans. is 'c' i.e., DNA synthesis Endoplasmic reticulum are involved in :-Rough ER : Protein synthesis (hormones, enzymes etc.)Smooth ER: Triglyceride synthesis, steroid synthesis, cholesterol synthesis, Phospholipid synthesis, fatty acid chain elongation.
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In a young patient presenting with recurrent vitreous hemorrhage, diagnosis is-
Ans. (a) Eale's diseaseRef: Pearson's 22/e, p. 344Eale's disease is characterized by recurrent bilateral vitreous hemorrhage in young adult (20 - 30 yrs) males.
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Genital elephantiasis is caused by -
Ans. is 'd' i.e., Lymphogranuloma venerum Lymphogranuloma venerum (lymphogranuloma inguinale)o LGV is caused by chlamydia trachomatis , serotypes LI, L2, L3. Serotype L2 is the most common cause. The clinical course of LGV consist of following three stages: -1) First stage (Primary LGV) : - Self limited, Single, asympt...
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A 2 year old child comes with ear discharge, seborrheic dermatitis, polyuria and hepatos- plenomegaiy. Which of the following is the most likely diagnosis -
Ans. is 'c' i.e., Langerhan's cell histiocytosis o Langherhans cells histiocytosis is a histocvtic. disorder most commonly characterized bv a single or multiple osteolytic bone lesions demonstrating infiltration with histiocytes.o Histiocytic disorders are derived from mononuclear phagocytic cells (macrophages) and den...
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Pre-cancerous lesion of bone?
Ans. is 'd' i.e., All of above Pre-cancerous lesion of bone Multiple exostoses Ollier's disease Benign giant cell tumor Osteoblastoma Chondroblastoma Chronic osteomyelitis Paget's disease
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All are true about P-value except
• ‘Type I error is usually fixed in advance’ by the choice of level of significance employed in the test • Type I error is more serious than Type II error • Power of a test: 1 – b – Is probability of rejecting a Null hypothesis when a predetermined clinically significant difference is indeed present – Power can be incr...
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Which of the following TRUE about rhinosporidiosis? NOT RELATED - ENT
Presents as a nasal polyp Rhinosporidiosis - It is fungal granuloma caused by Rhinosporidium seeberi. The disease mostly affects nose and nasopharynx The disease is acquired through contaminated water of ponds and cow-pets Presents as a leafy, polypoidal mass, pink to purple in colour and attached to nasal septum or la...
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You have treated the simple and undisplaced fracture of shaft of right tibia in a nine year girl with above knee plaster cast. Parents want to know the prognosis of union of the fractured limb which was affected by polimoyelitis four years age. What is the bet possible advice will you offer to the parents ?
"There is no significant delay in the rate of fracture healing in poliomyelitis".  — Skeletal injury in children
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Following are listed as (SpA) spondyloahritis features except
The spondyloahritides is a group of overlapping disorders that share ceain clinical features and genetic associations. These disorders include ankylosing spondylitis (AS), reactive ahritis, psoriatic ahritis and spondylitis, enteropathic ahritis and spondylitis, juvenile onset spondyloahritis (SpA), and undifferentiate...
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False about Japanese encephalitis:
No Man to Man transmission.
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There is no interruption in the axons but disruption of the myelin sheath is called:
(Neuropraxia) (51-M) (230-Apley's 8th)NEUROPRAXIA - It is due to mechanical pressure causing segmental demyelination and is seen typically in "crutch palsy" pressure paralysis in states of drunkenness (Saturday night palsy) and the milder types of tourniquet palsy.* Reversible physiological nerve conduction block in wh...
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The reciprocal inhibition of antagonist muscle upon lateral gaze is explained by
A i.e. Sherrington's law
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Thyroxine is synthesized from:
In dopaminergic cells in the brain, tyrosine is conveed to levodopa by the enzyme tyrosine hydroxylase (TH).TH is the rate-limiting enzyme involved in the synthesis of the neurotransmitter dopamine.In the adrenal medulla, tyrosine is conveed into the catecholamine hormones norepinephrine (noradrenaline), and epinephrin...
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In Schwaz formula for calculation of creatinine clearance in a child, the constant depends on the following EXCEPT
Schwaz formula (for creatine clearance in child) is Creatinine clearance = K x height/creatinine K = constant that depends upon age, muscle mass, method of creatinine estimation.
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30-year old male presents with flaccid bullae on an erythematous base and erosions over the oral mucous membrane. The blisters developed painful erosions rupture. What would be the most likely finding on an immunofluorescent examination of the sl biopsy of this patient?
Ans. c. Fish net IgG deposition in epidermis
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A 38-year-old man presented with episodes of severe headache. CNS imaging shows evidence of coical sinus venous thrombosis (CSVT). His mother has history of spontaneous recurrent DVT of bilateral lower limbs. Which of the following testing is the least likely to be indicated in this patient?
The patient is likely to have a hypercoagulable state, which is responsible for thrombosis at unusual site (coical venous sinus). There is positive family history of thrombosis also, indicating the underlying risk factor to be inherited. Hypercoagulable States: Primary (Genetic) Factor V Leiden mutation Prothrombin G20...
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Which among the following is false about Non Bacterial Thrombotic Embolism(NBTE) :
Vegetation in SLE Vegetation in NBTE Small, sterile, firm Both surface of valve Lower surface> upper surface Libman sack endocarditis Marantic endocarditis Along the line of closure Non invasive Don't elicit inflammatory reaction Small, Sterile Friable: Embolism Seen in - Ca Pancreases- AML M3 Vegetation of IE Vegetati...
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With respect to anorexia nervosa following is true except -
Ans. is 'd' i.e., Menorrhagia ANOREXIA NERVOSAo The term "anorexia nervosa " is a misnomer as loss of appetite is a rare symptom. This disorder is characterized by self imposed dietary restrictions leading to malnutrition and severe weight loss.Clinical featureso Females are far more commonly affected than males. Onset...
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All are true about primary CNS lymphoma except
Primary CNS lymphoma accounts for 2% of extra-nodal lymphomas and 1% of intra-cranial tumors. It is the most common CNS neoplasm in immunosuppressed individuals, including those with AIDS and immunosuppression after transplantation. Most primary brain lymphomas are of B-cell origin. In the setting of immunosuppression,...
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A young boy presented with lesion over his right buttock which had peripheral scaling and central scarring. The investigation of choice would be –
The boy is having lupus vulgaris because the lesions have central scarring. Central Scarring is a feature of lupus vulgaris. Diagnosis of lupus vulgaris is confirmed by Biopsy. Remember  Feature                                                                     Central clearing                                       ...
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A ventrolateral cordotomy is performed to produce relief of pain from the right leg. It is effective because it interrupts the:
Answer is B (Left Lateral Spinothalamic tract): `Neurosurgical Operations on the Spinal Cord' Pain sensations from the right leg are carried the contralateral Lateral Spinothalamic tract. Ventrolateral cordotomy (surgical procedure of ablating selected pain conducting tracts) of the Left Spinothalamic Tract should effe...
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Most common complication of central venous catheter
C i.e. Catheter related infection
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Di's collar is seen in the following condition:
After the bullet has perforated the skin, the elasticity of the skin causes the skin defect to contract. The skin is abraded (abrasion collar) around the hole due to rubbing of the gyrating body of the bullet against the inveed epidermis and heat of the bullet. A black coloured ring "grease or di collar" (bullet wipe s...
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Low serum haptoglobin in hemolysis is masked by-
Robbins basic pathology 8th edition, page no 424, Answer is option 1, bile duct obstruction Actually in hemolysis haptoglobin level decreases because some hemoglobin invariably escapes into the plasma. It is problably absent also. Haptoglobin is a circulating protein that binds and clears free hemoglobin. But the decre...
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Severe generalized edema is called as:
Severe generalized edema is called as Anasarca/dropsy.
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Uterine height is greater than gestational age of the patient in a case of all except -
Ans. is 'b' i.e., IUGR o Uterine height greater than gestational age in case of:a) Wrong datesb) Polyhydramniosc) Pregnancy with fibroid uterusd) Multiple pregnancy
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Ability of an organism to induce clinically apparent illness is known as:
Infectivity: It is the ability of an infectious agent to invade and multiply in a host. Pathogenicity: It is the ability of an organism to induce clinically apparent illness. Virulence: It is the propoion of clinical cases resulting in severe clinical disease. Ref: Park, 21st Edition, Page 34.
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True statement regarding ileum is -
Lymphatic patches (peyer's patches) are placed lengthwise along the antimesenteric border of the intestine. Vili in ileum is finger-like. The ileum is a midgut derivative and is therefore supplied by the superior mesenteric artery. Ileum joins the caecum on posterior-medial aspect of coecum.
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Pericardial space is present between -
Ans. is 'd' i.e.. Parietal and visceral pericardium o Pericardial space (pericardial cavity) lies between parietal serous pericardium and visceral serous pericardium.
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The Principal site of absorption of Sodium is :
A i.e. Proximal convoluted tubuleNormally about 60% of the filtered Na+ is reabsorbed in the proximal tubuleQ.Sodium ReabsorptionPercentageSite60%Proximal tubuleQ (by N a+ - H+ exchange)30%Thick ascending limb (by Na+ - 2C1+ - K+ cotranspo)7%Distal convoluted tubule (by Na+ - Cl- cotranspo)3%Collecting duct. ( ENaC cha...
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Which of the following is not a pa of management in grade III dog bite infected with rabies?
1. Wound should never be stitched immediately to prevent additional trauma that may help in spread of the virus in the deeper tissue. 2. "If suturing is necessary, then it has to be done after 24-48 hrs later, applying minimum stitches under the coverage of anti rabies serum locally"- Park. 3. Cleansing - wound should ...
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Virus responsible for non immune hydrops foetalis is?
Parvovirus is the commonest infectious etiology for hydrops foetalis. The other viruses implicated include Cytomegalovirus, Hepatitis B virus, Herpes simplex virus, Rubella virus and Adenovirus. Ref : Dutta book of obstetrics 8th Ed
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Abdominal pain, fat malabsorption and frothy stools suggests of
Giardia lamblia is an intestinal flagellate , infection acquired by ingestion of contaminated water and food and also by ano- oral sexual practice The parasite attaches itself to the epithelial surface of duodenum and jejunum causes a disturbance of intestinal function , leading to malabsorption of fat .patient complai...
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Most common cause of placenta pre:
A history of prior cesarean section and uterine curettage are significantly associated in patients with placenta pre. Placenta pre is most commonly found in Multiparous but most common cause is Previous cesarean section.
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36 year G2 P1 comes for antenatal visit at 10 weeks gestation. Her first child was female with ambiguous genitalia at birth, died at 6 months of age due to metabolic problem. Since this is her precious pregnancy, How would you counsel regarding risk of having child with ambiguous genitalia
This case scenario is suggestive of congenital adrenal hyperplasia. This is autosomal recessive disorder.  So, if any couple has had one affected child, subsequent baby has 1 in 4 chance of having similar disability.
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Which of the following is an example of a directly acting toxin?
Directly acting toxins: Some toxins act directly by combining with a critical molecular component or cellular organelle. For example, in mercuric chloride poisoning, mercury binds to the sulfhydryl groups of various cell membrane proteins, causing inhibition of ATP-dependent transport and increased membrane permeabilit...
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Hymen tear in virgin is most commonly located at -
Ref: Textbook of Forensic medicine and toxicology (V.V.Pillay) 17th edition, page no.355 As a result of sexualintercourse, hymen is usually torn posteriorly, with unilateral or bilateral tears extending to the point of its attachment to the vaginal wall. These ruptures bleed freely when, heal by scar formation.
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Which does not handle free radicals inside lens –
Enzymatic antioxidant mechanisms :- Reduced glutathione (most important), glutathione peroxidase, superoxide dismutase, catalase. Non-enzymatic defence mechanisms :- Vitamin C, Vitamin E, and possibly carotenoids. Some textbooks have also mentioned vitamin A as an anti-oxidant in lens. But, the best answer here is vita...
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Which of the following investigation is BEST used for placental localization?
The most accurate method for localisation of placenta is ultrasonogram. Its advantages are: It carries no risk to mother and fetus. It is the only method by which edge of the placenta can be seen, which helps in deciding the mode of delivery. Placental tissue shows up an area of fine speckling. Its fetal surface appear...
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Largest diameter of pelvic cavity: March 2013
Ans. D i.e. All are same Maternal pelvis MC type: Gynaecoid Platypelloid/ flat pelvis: Transverse diameter is more than AP diameter Least common type of pelvis: Platypelloid Deep transverse arrest/ persistent occipito posterior position is common in: Android pelvis AP diameter more than transverse diameter: Anthropoid ...
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Deep brain stimulation used in treatment of?
Ans. B.)Parkinsonism Deep brain stimulation It is a neurosurgical procedure involving the implantation of a medical device called a neurostimulator (sometimes referred to as a 'brain pacemaker'), which sends electrical impulses, through implanted electrodes, to specific targets in the brain (brain nuclei) for the treat...
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The persistent suppression of bacterial growth that may occur after limited exposure to some antimicrobial drug is called?
Ans. is 'c' i.e., Post antibiotic effect
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Most commonly varicose veins are seen with :
Ans. is 'a' ie. long saphenous vein (Schwart, 7/e, p 1021) (not mentioned in 8/e)" The usual distribution of veins is below the knee in branches of the greater saphenous system*
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Which is not produced enteroendocrinally
Enteroendocrinal cells are the hormone secreting cells present in the glands or mucosa of the GIT particularly stomach & intestine. The enteroendocrinal cells present in gastric glands are G cells- secrete gastrin Enterochromaffin (EC) cells- secrete serotonin Enterochromaffin like (ECL) cells- secrete histamine
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Charles Phillips procedure?
Ans. C. Recurrent small bowel obstruction. (Ref LB 25th pg. 1198)Rx of acute intestinal obstruction# GI drainage# Fluid and electrolyte replacement# Relief of obstruction# Surgical Rx is necessary for most cases of intestinal obstruction but should be delayed until resuscitation is complete, provided there is no sign o...
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Tranylcyprominle (MAO Inhibitor) should be avoided with ............... as it causes dangerous drug interaction:
MAO inhibitor with tricyclcic anti depressants (amitriptyline), reserpine , guanethidine can cause excitement , rise in BP and body temperature. This is due to their initial NA releasing it uptake blocking action. MAO inhibitor also interacts with cold and cough remedies that contain sympathetomimetic , levodopa , barb...
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NADH CoQ reductase is inhibited by
Inhibitors of electron transpo chainComplex I Complex II Complex III Complex IV AmobarbitalRotenonePericidin AGuanethidine Chlorpromazine Malonate Carboxin Antimycin A, BAL Naphthoquinone PhenforminCarbon monoxide CyanideHydrogen sulphide Azide Inhibitors of oxidative phosphorylationuBlocking reentry of protons through...
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Hypervitaminosis of which of the following will cause bony abnormalities?
HYPERVITAMINOSIS A: Chronic hypervitaminosis A results from excessive ingestion of preformed vitamin A (retinol or retinyl ester), generally for several weeks or months. Toxicity can be induced in adults and children with chronic daily intakes of 15,000 mg and 6,000 mg, respectively. Signs of subacute or chronic toxici...
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Regarding Gherlin which is false
Ghrelin is secreted primarily by the stomach and appears to play an impoant role in the central control of food intake. It also stimulates growth hormone secretion by acting directly on receptors in the pituitary.Ref: Ganong&;s review of medical physiology, 23rd edition Page no: 448
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Apremilast is
Ustekinumab, a monoclonal antibody to the shared IL-23/IL-12p40 subunit, is an efficacious treatment for psoriasis and has shown promise in Psoriatic ahritis in clinical trials. Other newer drugs that have shown efficacy for both psoriasis and PsA include the anti-IL-17 pathway agents, such as secukinumab and brodaluma...
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