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Dead bone in X ray is?
ANSWER: (A) More radiopaqueREF: Principles of bone x-ray diagnosis by George Simon p. 62Dead bone as seen in Aavascular necrosis, perthe's disease, TB, osteomyelitis is usually more opaque than normal in X ray
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The chemical name of Aspirin is?
Aspirin is Acetylsalicylic acid which conves to salicylic acid in the body, responsible for the action. ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION; KD TRIPATHI; PAGE NO 195
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All true about microlaryngoscopy tube (MLT) except:-
These tubes come in three sizes, 4.0, 5.0 and 6.0mm. The size 5.0mm tube is the most commonly used. Microlaryngoscopy tube (MLT) vs. standard ETT The MLT is often used in place of a standard small diameter ETT to facilitate Direct Laryngoscopic procedures utilizing Microlaryngoscopy techniques. The surgeon prefers a sm...
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Normal diurnal variation of intraocular pressure is:
Ans. 3-6 mm of Hg
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Defluoridation of water is carried out using:
Some areas may contain excessive fluoride levels in drinking water. Defluoridation is carried out using phosphates. Ref: Park 21st edition page: 672.
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Nephron is derived from ?
Development of kidneyUreteric bud (mesonephros) arise from mesonephric duct and gives rise to collecting system of kidney (renal pelvis, major and minor calyces, collecting tubule) and ureter.Metanephric mesoderm (blastema or metanephors) arise from nephrogenic cord which in turn is derived from intermediate mesoderm. ...
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All of the following support uterus except
Ans. is b, i.e. Round ligamentRemember* Most important support of uterus is levator ani muscle* Most important ligament supporting the uterus--Cardinal ligament/Mackenrodt's ligament* Round ligament is a secondary support of the uterus as it does not support it directly but helps to keep it in anteverted position* Broa...
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What is the effect of beri beri on circulation ?
high output congestive hea failure occurs in beri beri ( Harrison 17 pg 442)
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Tumours most common to cause early papilledema arise from:
Ans. All of the above
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Urothelium lines all Except -
Urothelium (transitional epithelium) is found in the renal pelvis, calyces, ureter, urinary bladder, proximal part of the urethra. Membranous and most of the penile urethra (in males) is lined by pseudostratified or stratified columnar epithelium.
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In Cochlear implants, the electrodes are most commonly placed at:
The cochlear implant electrodes are placed in the scala tympani of the cochlea. The electrode thus stimulates the cochlear nerve which is a pa of the vestibulo-cochlear nerve (CN VIII).
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Normal urea excretion rate is?
Ans. is 'b' i.e., 10-20 gm/day(Ref: Medical physiology E Book 2d/e p. 767)"The physiologically normal individual excrete 12-20 gm of urea nitrogen in 24 hours"
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A 35-year-old male with history of 4 weeks of immobilization for fracture femur developed sudden onset of chest pain and hemoptysis. ECG shows SI Q3 T3 pattern. Diagnosis?
Ans. c. Pulmonary embolismPULMONARY EMBOLISMPulmonary embolism usually arises from a venous thrombosis in the pelvis or legs.Risk factors include any cause of immobility or hyper coagulability.Clinical sign and symptoms:DyspneaTachycardia and hypoxemia are prominent.Pain is usually pleuritic, especially when pulmonary ...
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Planning cycle includes –
Planning involves a succession of steps                       Analysis of health situation      Establishment of objectives and goals   Assessment of resources    Fixing priorities  Programming and implementation Write-up of formulated plan  Monitoring  Evaluation.
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All of the following are mediators of acute inflammation except -
. Angiotensin
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Least cardiotoxic agent –
Cardiac output is best maintained by Isoflurane by reflex tachycardia as it does not depress baroreceptor reflex → Most cardiovascular stable inhalational agent → Inhalational agent of choice for cardiac surgery.
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Patient came into emergency department with flexion, adduction and internal rotation of hip. Diagnosis?
Ans. (b) Posterior dislocation of hipRef: Maheshwari 5th ed. /130POSTERIOR DISLOCATION OF HIP* It is most common type of hip dislocation in adults and children.* Usually this occurs in a road accident when someone seated in car is thrown forwards, striking the knee against the dashboard (dashboard injury)* It is the po...
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A girl from shimla presented to OPD with fever, hypotension, malaise and axillary and inguinal lymphadenopathy. Culture in glucose broth shows stalactite growth. Most likely causative organism is?
This is a case of bubonic plague. Plague is caused by Yersinia pestis. It is sho plump, ovoid, gram negative bacillus, shows bipolar staining (safety pin appearance), pleomorphism which is characteristically enhanced in media containing 3% NaCl. It is enveloped by a slime layer & is non motile, non sporing, non acid fa...
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Hoarseness secondary to bronchogenic carcinoma is usually due to extension of the tumour into ?
Ans. is 'c' i.e., Left recurrent laryngeal nerve
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Treatment of pseudocyst of pancreas include ?
Ans is d i.e. All of the above
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All of the following are examples of mydriatics except –
Cycloplegics (paralysis of accommodation + mydriasis) → Atropine, Homatropine, Cyclopentolate, tropicamide Only mydriatics → Phenylephrine. Note : Cycloplegic action of tropicamide is unreliable.
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Type of collagen forming basement membrane of kidney-
Type IV collagen with laminin are the major constituent of basement membrane.
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A standing person lies down. Which of the following occurs?
Ans. b. Immediately increase in venous return to heart (Ref: Ganong23/e p515)Factors Affecting End Diastolic VolumeFactors Decreasing EDVFactors Increasing EDV* Increased intra-pericardial pressureQ (as a result of infection of pressure from a tumor):- Limits the extent to which ventricle can fill* Decrease in ventricu...
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Which of the following statement is true about external haemorrhoids?
It presents as a suddenonset, olive-shaped, painful blue subcutaneous swelling at the anal margin and is usually consequent upon straining at stool, coughing or lifting a heavy weight .The thrombosis is usually situated in a lateral region of the anal margin. If the patient presents within the first 48 hours the clot m...
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Acute endocarditis with abscess is most commonly associated with?
Ans. (b) StaphylococcusRef: Harrison's 18th ed ch:124, Braunwald's HeartDisease: A Textbook of Cardiovascular Medicine 18thed ch-63
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Softening of the vaginal poion of the cervix:
Goodell sign:- Softening of the cervix , 6th to 8th weeks Chadwick / jacquemier's sign:- Bluish discoloration of the cervix , 6th to 8th weeks Hegars sign : On p/v the abdominal and vaginal fingers seem to oppose below the body of uterus ,6th wk Osiander (vaginal ) sign :-Pulsatality in lateral fornices, around 8th wee...
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Hemmorhagic fever is not caused by -
kyasanur foerst disease a hemorrhagic fever found in karnataka. It is arboviral disease. A new arbo virus genetically related to RSSE isolated ANANTHANARYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PGNO.524
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Which one of the following is the description used for the term allodynia during pain management?
Ans. is 'd' i.e. Perception of an ordinarily nonnoxious stimuli as severe pain Terms used in pain managementAllodyniaPerception of an ordinarily nonnoxious stimulus as painAnalgesiaAbsence of pain perceptionAnaesthesiaAbsence of all sensationsDysesthesiaUnpleasant or abnormal sensation with or without a stimulusHypalge...
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Maximum loss of sodium in a child occurs in?
Cations and anions in biological fluids in meq/dl Fluid Sodium Potassium Chloride Gastric juice 60 10 85 Ileal fluid 130 10 115 Diarrhea stool 10-90 10-80 10-110
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Circuit for spontaneous respiration in adults:
Ref. Oxford textbook of anesthesia. Page. 330   Spontaneous respiration: A>D,E>C >B IPPV :D&E> B> C> A Mapleson A : For adult Magill system Flow rate = Minute volume Mapleson B: - not used Mapleson C : Water system Choice in Post operative room Mapleson D: Bain – Coaxial system Most effective in assisted control v...
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Which of the following contains site of attachment of calcium ions that initiates muscle contraction?
Troponin T binds the troponin components to tropomyosin; troponin I inhibits the interaction of myosin with actin; and troponin C contains the binding sites for the Ca2+ that helps to initiate contraction. Ganong 23 rd ed, pg 96
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Most important bactericidal agent is
H2O2- MPO- halide system is the most efficient bactericidal system of neutrophils
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According to a newer hypothesis Ewings, sarcoma arises from -
Marrow tumors (medullary cavity tumors) : - Ewings sarcoma, Plasma cell tumor, multiple myeloma, Lymphoma.
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Burst abdomen most commonly occurs on the
Ans. is 'c' i.e., 7"' day
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The following hand deformity is seen in?
This is a case of complete claw hand (clawing of all fingers). It is seen in:1. Median plus ulnar nerve injury2. Klumpke's palsy as it involves root value of ulnar nerve & medial root of median nerve- T1 & C8.
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Parasympathetic postganglionic fibres are carried by the
Long ciliary nerves are mixed sensory and sympathetic. Greater petrosal nerves carries preganglionic parasympathetic fibers from the facial nerve to the pterygopalatine ganglion. The deep petrosal nerve carries mainly sympathetic fibres from the superior cervical ganglion and internal carotid plexus.
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According to European laryngeal Society classification, subligamental endoscopic cordectomy is which of the following types?
Classification of endoscopic cordectomy: Type I : Subepithelial cordectomy Type II : Subligamental cordectomy Type III: Transmural cordectomy Type IV: Total cordectomy Type V : Extended cordectomy Type VI : Anterior commisurectomy with bilateral anterior cordectomy
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Root value of tendocalcaneus reflex?
ANSWER: (C) S1, S2REF: Harrison's 18th ed ch: 367Repeat (**)Root value of some important deep tendon reflex: (Major contribution m bold;Jaw jerkBoth the sensory and motor aspects of this reflex are through CN V (Trigeminal nerve)Biceps(C5, C6),Brachioradialis(C5, C6)Triceps(C7, C8)Patellar or quadriceps: knee jerk(L3, ...
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Restrinction Endonucleas function --> true about:
A i.e. Cut both strands of ds DNA; B i.e. Cut ends produced are sticky; C i.e. Cut end produced are blunt
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Substitution of which one of the following amino acids in place of alanine would increase the absorbance of proteins at 280 mm:
The only amino acids that may absorb light are Aromatic amino acids i.e. Tryptophan, Tyrosine, Phenylalanine & Histidine- Most a.a do not absorb visible light & are thus colourless- Aromatic aminoacids absorb ultraviolet light (250- 290 nm).- Tryptophan makes major contribution to ability of most proteins to absorb lig...
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Nitrogen narcosis is caused due to
Nitrogen has anesthetic effect on body The precise mechanism is not well understood, but it appears to be the direct effect of gas dissolving into nerve membranes and causing temporary disruption in nerve transmissions. While the effect was first observed with air, other gases including argon, krypton and hydrogen caus...
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On the ribosome, mRNA binds
During initiation, the small ribosomal subunit binds to the start of the mRNA sequence. Then a transfer RNA (tRNA) molecule carrying the amino acid methionine binds to what is called the start codon of the mRNA sequence.
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True about ACELLULAR PERTUSSIS VACCINE include the following EXCEPT
Ans. b (Ref. OP Ghai 6th/pg.l94; Nelson paeds 17th /pg.908)PERTUSSISPreventionUniversal immunization of children <7 yr of age with pertussis vaccine, beginning in infancy, is central to the control ofpertussis. Current goals of immunization are protection of the individual from a significant coughing illness and contro...
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A patient who underwent surgery for stage IA grade 3 Ca endometrium was brought to you for postoperative adjuvant therapy. What is the preferred mode of treatment in the above mentioned case?
The postoperative adjuvant therapy for different stages of Ca endometrium is given below Stages Adjuvant therapy Stage IA, G1, G2 Observation Stage IA, G3 Vaginal brachytherapy Stage IB, G1, G2, G3 & Stage II, Stage III A ,B, C1, G1, G2, G3 External pelvic radiation + vaginal brachytherapy Stage III ,C2, G1, G2, G3 Ext...
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Drug which clears trypanosomes from blood and lymph nodes and is active in late CNS stages of African sleeping sickness
Melarsoprol in cns stage, suramin in heamolymphaticstage, chagas disease nifuimox.Ref: Katzung 10/e p863
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The WHO announced, immunisation is a primary responsibility of -
Ans. is 'a' i.e., States
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Which of these is not associated with Loeffler’s syndrome?
Loeffler’s syndrome causes are as follows: • Ascaris • Ancylostoma sp. • Toxocara sp. • Strongyloides stercoralis • W bancrqfti or W malayi • Trichomoniasis • Clonorchiasis • Visceral larva migrans, etc.
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Chocolate Brown postmoem staining is seen in -
In poisoning by nitrites, potassium chlorate, nitrobenzene, potassium bicarbonate and aniline the colour of postmoem hypostasis is chocolate brown due to methhemoglobinemia. Dr.Narayana Reddys Synopsis of Forensic Medicine and Toxicology 27th edition pg. 76.
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The graph showing relationship between cervical dilatation and duration of labour is :
Cervicograph
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Streak gonads are seen in
Most patients have primary amenorrhea, and morphologic examination reveals transformation of the ovaries into white streaks of fibrous stroma devoid of follicles.the ovaries are reduced to atrophic fibrous strands, devoid of ova and follicles (streak ovaries).It is the defective development of the gonads in an embryo, ...
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Depressors of Mandible -
Depressors of the mandible are:- Muscle of mastication: Lateral pterygoid (major depressor). Suprahyoid muscles: Digastric, mylohyoid, geniohyoid. Elevators of the mandible are:- Muscles of mastication: Masseter, temporalis, medial pterygoid.
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Characteristic feature of diabetic retinopathy: September 2005, 2010 March 2007
Ans. D: Microaneurysm Diabetic retinopathy is an ocular manifestation of systemic disease which affects up to 80% of all patients who have had diabetes for 10 years or more. Diabetic retinopathy often has no early warning signs. As new blood vessels form at the back of the eye as a pa of proliferative diabetic retinopa...
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Most common cause of acute polyneuropathy is
(B) Guillian Barre syndrome # Myocarditis & Polyneuropathy are the prominent toxic manifestations of diphtheria. The risk of each is proportional to the severity of local disease.> Polyneuropathy typically begins 3 to 5 weeks after onset of diphtheria and has a slow course. It appears earliest in patients who experienc...
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Better prognostic factor for operation of biliary duct obstruction in newborn are -
Answer (b) Size of ductule > 200 micron Surgical treatment of biliary atresia Pooenterostomy or Kasai's operation is the surgery of choice. The purpose of this procedure is to facilitate the flow of bile into the intestine. It is based on the observation that the fibrous tissue at the pa hepatitis invests microscopical...
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Parotitis and orchitis are common manifestations of:
d. Mumps(Ref: Nelsons' 20/e p 1552-1553, Chai 8/e p 217-218)Mumps is characterized by fever, bilateral or unilateral parotid swelling and tenderness, and the frequent occurrence of meningoencephalitis and orchitis.
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Acute vascular ischemia mainfests as
Peripheral aery occlusion Clinical features of peripheral aerial occlusion are classically remembered by 5 P's : pain, pallor, pulselessness, paralysis and paraesthesia Some add 6th P: Poililothermia or perishing cold Most common presenting symptom of acute aerial occlusion : Pain Ref: Sabiston 20th edition Pgno :1756
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Incudomalleolar joint is a;
The incudomalleolar joint is a saddle joint while the incudostapedial is a ball and socket joint. Both of them are synol joints covered by capsular ligament.
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All of the following are the adverse effects of tacrolimus except -
Ans. is 'c' i.e., Hirsutism
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Maximum carbohydrate concentration in strict vegetarian diet present is
(Glycogen) (21- U.Satyanarayan 3rd)GLYCOGEN - is the carbohydrate reserve in animals, hence often referred to as animal starch*** It is present in high concentration in liver, followed by muscle, brain* The enzyme hyaluronidase of semen degrades the gel (contains hyaluronic acid) around the ovum. This allows effective ...
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True about incontinenta pigmenti include the following except aEUR'
Ocular involvement is seen in almost 100% cases and is typically unilateral Incontinentia pigmenti Incontinentia Pigmenti (IP), also referred to as Bloch- Sulzberger syndrome is an unusual inherited disorder of skin pigmentation that is associated with abnormalties of :- i) Skin --) (100% of affected people) ii) Teeth ...
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A diabetic female at 40 wks of gestation delivered a baby by elective cesarean section. Soon after birth, the baby developed respiratory distress. The diagnosis is -
Ans. is 'a' Transient tachypnea of the newborn (Ref. Nelson, 16th/e, p. 505; Ghai O.P., 5th/e, p. 145).lam going against the majority in this question. Most of the students believe that the answer is a Hyaline membrane.Now read carefully what Nelson has to say about HMD." Hyaline membrane disease occurs primarily in pr...
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Which of the following is an SGLT 2 inhibitor approved for treatment of type 2 diabetes Mellitus
Canagliflozin, empagliflozin, dapagliflozin, remogliflozin are sglt 2 inhibitors approved for treatment of type 2 diabetes Ref Harrison 20th edi page no 2866, table 397-5
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Cause of vaginal bleeding in an ectopic pregnancy is shedding of the endometrium. This endometrium is known as:
Decidua directly beneath blastocyst implantation becomes the deciduas basalis. The decidua capsularis overlies the enlarging blastocyst and initially separates the conceptus from the rest of the uterine cavity. The remainder of the uterus is lined by deciduas parietalis. By 14 to 16 weeks' gestation, the expanding sac ...
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Capillary refill time in a child with shock is
Capillary refill is a simple test that assesses how quickly blood returns to the skin after pressure is applied. It is carried out by applying pressure to the pink pa of the nail bed of the thumb or big toe in a child and over the sternum or forehead in a young infant for 3 seconds. The capillary refill time is the tim...
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Contraindication of rota virus vaccine is
Ans. is 'd' i.e., All of above
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Adenylate cyclase conves
Adenylate cyclase (calmodulin-sensitive) trimer, Bacillus anthracis Epinephrine binds its receptor, that associates with a heterotrimeric G protein. The G protein associates with adenylyl cyclase, which conves ATP to cAMP, spreading the signs
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Pulsatile proptosis is a feature of ?
Ans. is 'c' i.e., Coico-cavernous fistula Proptosis Proptosis is bulging of the eyeball (forward bulging) beyond the orbital margins. Though the word exophthalmos is synonymous with proptosis; some source define xophthalmos as a protrusion of globe greater than 18mm and proptosis as a protrusion equal to or less than 1...
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Ultra-structurally, endothelial cells contain:
Endothelial cells are the major source of plasma vWF, whereas most factor VIII is synthesized in the liver. vWF is found in the plasma (in association with factor VIII), in platelet granules, in endothelial cells within cytoplasmic vesicles called Weibel-Palade bodies, and in the subendothelium, where it binds to colla...
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Not a feature of alcohol withdrawal is:
Hypersomnolence
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Which of the following features is shared in common between lymphocyte-rich and lymphocyte-predominant types of Hodgkin's lymphoma?
Ans. d (Prognosis is excellent) (Ref. Robbins 7th/689)Paragraph from Robbins Pathology 7th ed. p. 688, Table 14-6:Lymphocyte-rich:Lymphocyte predominance:# Frequent mononuclear & R-S cells0# Paucity of RS cells # 40% EBV+.Q# R-S cells CD20+, CD15-, C30-;# CD20 and CD 45-Q# EBV--Q.# Very good to excellent prognosis.# Ex...
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The most common laser used in laryngeal surgery is
The LASER is an acronym for Light Amplification by Stimulated Emission of RadiationDepending upon the lasing medium, various types of lasers with differing wavelength can be created. The lasing medium can be solid (ruby, Nd: YAG or potassium titanyl phosphate); gas (CO2 or Helium-Neon) or liquid (pumped inorganic dye i...
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Malignant melanoma of conjunctiva is usually of:
Ans. All of the above
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Upper segment to lower segment ratio at bih is ___________
The U/L ratio (upper body segment :lower body segment) at bih is about 1.7; at age 3 years it is 1.3; at greater than 7 years, it is 1.0 with the upper body segment and lower body segment being about equal. Of note, higher U/L ratios are noted in sho-limb dwarfism and other bone disorders such as rickets. Reference: GH...
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Characteristic of Guillain-Barre syndrome is: September 2005
Ans. B: Loss of limb reflex
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Cretinism is _____________
Congenital iodine deficiency syndrome, previously known as cretinism, is a condition of severely stunted physical and mental growth owing to untreated congenital deficiency of thyroid hormone (congenital hypothyroidism) usually owing to maternal hypothyroidism. Results in Dispropoionate dwarfism Reference: GHAI Essenti...
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In a young temale ot reproductive age with regular menstrual cycles of 28 days, ovulation occurs around 14lh day ot periods. When is the tirst polar body extruded ?
Accompanied by ovulation Most of the standard text books say the first polar body is expelled just before or sholy before ovulation. -- Which does not mean that it is released 24 hrs before ovulation. "While still in the ovary the ovum is in the primary oocyte stage. Sholy before it is released from ovarian follicle (i...
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On sonography a multigravida found to have oligohydramnios. Which among the following will be associated with this condition?
Congenital Anomalies Associated with Oligohydramnios: Amniotic band syndrome Cardiac: Fallot tetralogy, septal defects Central nervous system: holoprosencephaly, meningocoele, encephalocoele, microcephaly Chromosomal abnormalities: triploidy, trisomy 18, Turner syndrome Cloacal dysgenesis Cystic hygroma Diaphragmatic h...
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Chromosome defective in cystic fibrosis is-
Cystic fibrosis or fibrocystic disease is a hereditary disorder characterized by viscid mucous secretions in all the exocrine glands of the body (mucoviscidosis) and associated with increased concentrations of electrolytes in the eccrine glands. The terms 'cystic fibrosis' and 'fibrocystic disease' is preferable over '...
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U shaped dose response curve is seen in
U shaped response curve is seen in vitamins Ref-Goodman and Gillman 12/e p74
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True about Light microscopic changes in Minimal Change Glomerulonephritis is:
Answer is A (No abnormality) Light microscopy shows no abnormality in Minimal change Disease Investigation Light microscopy Q Electron microscopy Q Immunofluorescence Q Observation No abnormality hence the term minimal change Fusion offoot processes / Effacement offoot process Absence of immunoglobulin or complement
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Regan enzyme is an isoenzyme of ?
Ans. is 'd' i.e., Alkaline phosphataseRegan enzyme (isoenzyme) is the isoenzyme of alkaline phosphatase.It arises from placenta know as carcinoplacental enzyme.It is elevated in about 15% fo cases of carcinoma of lung, liver and gut.
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Long thoracic nerve arises from nerve roots -
Ans. is 'c' i.e., C5 C6 C7 o Root value of long thoracic nerve is C5C6 C7Supraclavicular branches of brachial plexuso Branches of brachial plexus which are above the clavicle are called supraclavicular branches.o These arise from roots and trunks.Supraclavicular branches of brachial plexusFrom roots1. Nerves to scaleni...
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Causative agent for Farmers' Lung is?
Ans. is 'b' i.e., Thermophiles actinomyces * Farmer's lung is a hypersensitivity (type III) pneumonitis induced by the inhalation of biologic dusts coming from hay dust or mold spores or any other agricultural products.* These types of immune response are most often initiated by exposure to thermophilic actinomycetes (...
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What are the minimum number bacilli for Sputum positive Tuberculosis?
Answer: D. 104. (Ref Park's Textbook of PSM 22nd/Pg.l71)Sputum smear microscopy for tubercle bacilli is positive when there are at least 10,000 organisms present per ml of sputum.For slide reporting :No. of BacilliResult reportedNo AFB/100 oil immersion fields01-9 AFB/100 oil immersion fieldsScanty ( or Number AFB seen...
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Which among the following is the most common cause of stroke associated with moality?
Strokes are classified as either hemorrhagic or ischemic. Acute ischemic stroke refers to stroke caused by thrombosis or embolism and is more common than hemorrhagic stroke. Cardiogenic emboli are a common source of recurrent stroke. They may account for up to 20% of acute strokes and have been repoed to have the highe...
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Brittle bone disease is -
Osteogenesis imperfecta is also known as Fragilitas ossium or Vrolick&;s disease which is characterised by tendency for frequent fractures because of weak and brittle bones. It results from defective collagen synthesis and thus affects other collagen containing soft tissues like skin, sclera, teeth, ligaments etc. as w...
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In a completely and adequately immunized child against Diphtheria, the throat swab was collected. It showed the presence of Corynebacterium diphtheriae like organisms on Albe staining. These organisms can have one of the following propeies on fuher laboratory processing
Smears stained with methylene blue or one of the special stains(Neisser's or Albe's )will show the bacilli with metachromatic granules. Albes stain may show delicate green bacilli with purple-blue metachromatic granules. For culture, the swabs are inoculated on Loeffler's serum slope, tellurite blood agar and a plate o...
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Which is the most impoant element in treatment of diphtheria?
The most impoant element in treatment of diphtheria is antitoxin. Option 1 1. Treatment of diphtheria: Treatment should be staed immediately on clinical suspicion of diphtheria. 2. Anti-diphtheritic horse serum or ADS (antitoxin): It is the treatment of choice as it neutralizes the toxin. Serum antitoxin concentration ...
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All of the following are signs of inadequate breast milk intake in a neonate, EXCEPT:
In a neonate with inadequate breast milk intake the weight loss is more than 8-10%. Other signs of inadequate breast milk intake are: Less than six noticeably wet diapers per 24 h by day 3-4 Less than four stools per day by day 3-4 Nursing less than eight times per 24 h Breast milk jaundice: refers to presence of uncon...
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Abatacept, a new drug inhibiting co-stimulation is used for-
Ref Davidsons 23e p1007
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All true about classical Rapid sequence induction except
Rapid Sequence induction /intubation Indication - emergency surgery, full stomach patient (Pregnancy is considered afull stomach,whererapid sequence induction is indicated if taken under general anesthesia) Aim - to prevent aspiration Steps 1. Preoxygenation 2. Cricoid pressure application 3. Intravenous thiopentone an...
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Fibrin is degraded by ?
Coagulation must be balanced with fibrinolysis to limit the hemostatic plug to the site of injury. Injured vascular endothelium secret plasminogen activator that conves inactive plasminogen to active plasmin. Plasmin breaks down fibrin resulting in production of fibrin degradation products. Fibrinolytic system is regul...
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Hypehyroid state is characterized by
People with hypothyroidism often have no or only mild symptoms. Numerous symptoms and signs are associated with hypothyroidism, and can be related to the underlying cause, or a direct effect of having not enough thyroid hormones. Hashimoto's thyroiditis may present with the mass effect of a goiter (enlarged thyroid gla...
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All are false about tigecycline, except:-
Tigecycline Belongs to glycylcycline Group. Is active against most bacteria that have developed resistance to the classical tetracyclines. Acts by inhibiting protein translation in bacteria by binding to the 30S ribosomal subunit. It blocks entry of amino-acyl tRNA molecules into the A site of the ribosome. Active agai...
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Bennet's fracture involves which metacarpal bone?
Ans. a (1st metacarpal). (Ref. Maheshwari, Orthopaedics, 2nd/pg.98)RENNET'S FRACTURE# Bennet's fracture is an oblique intra-articular fracture of the base of 1st metacarpal with subluxation or dislocation of the metacarpal.# Rx by accurate reduction & restoration of the smooth joint surface is important as any abnormal...
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Best test for GFR is with:
A i.e. Inulin (Measurement of GFRGFR can be measured by measuring the excretion & plasma level of a substance that is freely filtered through glomeruli and neither secreted not reabsorbed by the tubulesQ.Requirement of substances used to measure GFR- Substances used- Filtered freely- Inulin (standard)Q- Neither reabsor...
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The most frequent site of branchial cyst is at
The branchial cyst is common in the second decade of life but can occur at any age with equal frequency in both sexes. Cyst presents as a swelling in the upper pa of the neck anterior to the sternocleidomastoid muscle. Mass is smooth, round, fluctuant, non-tender and not transilluminate. A painful increase in size at t...
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Which type of adenoma has the highest propensity to undergo dystrophic calcification?
Lactotroph adenomas have a propensity to undergo dystrophic calcification, ranging from isolated psammoma bodies to extensive calcification of viually the entire tumor mass ("pituitary stone").
151,397
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A widely used drug that suppresses cellular immunity inhibits prostaglandin and leukotriene synthesis and increases the catabolism of IgG antibody is :
Glucocorticoids are powerful immunosuppressants. These inhibit both cellular and humoral immunity by: Decreasing the recruitment of immune cells. Catabolism of immunoglobulins. Inhibiting the enzyme phospholipase A2 resulting in decreased production of PGs, LTs and TXs.
151,398
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Which of the following anti-diabetic drugs can cause vitamin B12 deficiency?
Ans. (C) Metformin(Ref: Goodman Gilman 12/e p1259, KDT 8/e 299)Lactic acidosis (more with phenformin) and megaloblastic anemia (more with metformin) due to vitamin B12 deficiency are the major adverse effects of these drugs. Lactic acidosis is more likely to occur in the presence of hepatic and renal impairment or alco...
151,399
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