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Landau-Kleffner syndrome is characterized by all of following except | Ans. C. Normal EEG during sleep Ref : Nelson Textbook of Pediatrics 20th/ed p2837ExplanationLandau-Kleffner syndrome is a condition of unknown cause characterized by:# Loss of language skills attributed to auditory agnosia in a previously normal child# Seizures (focal, generalized tonic-clonic, atypical absence, partia... | 155,500 | medmcqa_train |
Nicotinic acid ? | Ans. is 'a' i.e., Increases HDL Nicotinic acid (Niacin) There arc three main type of lipases related to metabolism of lipoproteins ? Lipoprotein lipase - Present in blood vessels and causes hydrolysis of tryglyceride content of VLDL and chylomicrones. Hepatic lipase - Conves IDL to LDL by hydrolysing the triglyceride c... | 155,501 | medmcqa_train |
Circulus aeriosus iridis major is formed by the anastomosis of | Anterior ciliary aeries: These are derived from the muscular branches of ophthalmic aery. These aeries pass anteriorly in the episclera, give branches to sclera, limbus and conjunctiva; and ultimately pierce the sclera near the limbus to enter the ciliary muscle; where they anastomose with the two long posterior ciliar... | 155,502 | medmcqa_train |
A 20 year old patient presents with syncope. His current ECG is shown below. His elder brother had died suddenly while watching television. The patient was given Cardioversion and subsequent cardiac MRI revealed fibro-fatty changes in RV myocardium. What is the diagnosis of this patient? | Arythmogenic RV dysplasia(ARVD) ECG shows HR of 300/min with broad complex tachycardia. Variation in amplitude of QRS complexes which indicates a diagnosis of polymorphic Ventricular Tachycardia. In acute setting DC shock 200 J Biphasic should be given. The Cardiac MRI repo showing fibro-fatty changes in RV myocardium ... | 155,503 | medmcqa_train |
Most common phase I biotransformation reaction is? | Ans. is 'a' i.e., Oxidation Oxidation is the most impoant metabolizing reaction. | 155,504 | medmcqa_train |
Sulfasalazine is used in - | Ans. is 'a' i.e., Ulcerative colitis Inflammatory bowel disease (crohn's disease & ulcerative colitis)o 5-aminosalicylic acid (5-ASA) is the main anti-inflammatory compound that acts locally in colon. It is the first line of treatment in mild to moderate UC and CD. When given alone 5-ASA is absorbed > 80% in proximal i... | 155,505 | medmcqa_train |
Kaposi sarcoma is caused by: March 2013 | Ans. C i.e. HHV 8 Kaposi sarcoma (KS) It is a tumor caused by Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV). It was originally described by Moritz Kaposi , a Hungarian dermatologist practicing at the University of Vienna in 1872. It became more widely known as one of the AIDS-de... | 155,506 | medmcqa_train |
All of the following are examples of microdeletion syndromes, EXCEPT: | The term contiguous gene syndrome refers to genetic disorders that mimic a combination of single-gene disorders. They result from the deletion of a small number of tightly clustered genes. Because some are too small to be detected cytogenetically, they are termed microdeletions. The application of molecular techniques ... | 155,507 | medmcqa_train |
All are true for PTSD except | D i.e. Anxiolytic is treatment of choice | 155,508 | medmcqa_train |
Which of the following is true regarding Pneumothorax? | Spontaneous pneumothorax in most patients occurs from the rupture of blebs and bullae. Primary spontaneous pneumothorax (PSP) is typically observed in tall, young people without parenchymal lung disease and is thought to be related to increased shear forces in the apex. Secondary spontaneous pneumothoraces (SSP) occur ... | 155,509 | medmcqa_train |
'Herald patch' is seen in: | Ans. A. Pityriasis rosea. (Ref. Harrison's 18lh/pg. 367)In Pityriasis rosea, initially, there is a single 2- to 6-cm annular salmon-colored patch (herald patch) with a peripheral rim of scale, followed in days to weeks by a generalized eruption involving the trunk and proximal extremities.Pityriasis rosea:# It is an ac... | 155,510 | medmcqa_train |
A 34-year-old man is brought to the emergency room by his family because of extreme lethargy. After further questioning, he admits to taking a large number of phenobarbital tablets. Which of the following is the most appropriate next step in management? | Activated charcoal absorbs barbiturates very effectively and is useful in decontamination of the GI tract. Renal elimination of phenobarbital is enhanced by alkalinization of the urine to a pH of 8 with sodium bicarbonate and fluids. Hemodialysis and hemoperfusion are reserved for extreme cases with refracting hypotens... | 155,511 | medmcqa_train |
Degree of freedom for 2/2 contingency table is? | Ref: Parks 23rd edition Degree of freedom = (r-1)(c-1) =(2-1)(2-1)= 1 | 155,512 | medmcqa_train |
Most common cause of lobar hemorrhage in the elderly | Answer- C. Amyloid angiopathyLobar intracerebral hemorrhage is bleeding in the largest pa of the brain called the cerebrum.Intracerebral hemorrhage are attributed to hypeensive vasculopathy in small penetrating brain aeries and subcoical vessels in patients with amyloid angiopathy.Amyloid angiopathn a chronic depositio... | 155,513 | medmcqa_train |
Which of the following is not true about spasmodic dysphonia | SPASMODIC DYSPHONIA Spasmodic dysphonia is also called as laryngeal dysphonia. The condition is characterised by spasm of phonatory muscles. It is a neurological disorder and is of following types: (A) Adductor spasm (M/C):- Adductor muscles go into spasm lead ing to strained and strangled voice (scratchy creaky voice)... | 155,514 | medmcqa_train |
Which of the following organism is biggest ? | Ans. is 'a' i.e., Balantidium coli | 155,515 | medmcqa_train |
Drug producing haematological side effect is: | Ans: A (Nitrous oxide) Ref: Ajax Yadav, Short Textbook of Anesthesia, 1st edition, pg 59.Explanation:Nitrous oxide produces Aplastic anemia and Megaloblastic anemiaNITROUS OXIDE (LAUGHING GAS)Stored as liquid in blue color cylinderE5 times more heavier than air35 times more soluble than nitrogenAnesthetic propertiesIt ... | 155,516 | medmcqa_train |
A patient presents with endocrinopathy. fibrous dysplasia of bone and hyperpigmentation. What should be the possible diagnosis? | Mc Cune Albright syndrome is a triad of Precocious puberty (endocrinopathies) fibrous dysplasia, cafe-au-lait spots. | 155,517 | medmcqa_train |
Paneth cells characterized by | Paneth cells are zinc-containing cells widely distributed in Lieberkuhn's crypts of small intestine in many species, but their function has remained obscure. Our previous study showed that a single intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, forms zinc-dithizonate complexes in the cytop... | 155,518 | medmcqa_train |
The following drug has significant drug interaction with the digoxin except | Cholistyramine inhibits intestinal absorption of digoxin Thiazides result in hypokalemia and thus me precipitate digitalis toxicity by pharmacodynamic interaction Quinidine and verapamil reduces the excretion of digoxin and Thus may precipitate the toxicity(pharmakokinetic interaction) Refer kDT 6/e p499 | 155,519 | medmcqa_train |
Acute cholinesterase inhibitors intoxication include all of the following except | Cholinesterase inhibitors have cholinomimetic actions. The major source of such intoxications is pesticide use in agriculture.The dominant initial signs are those of muscarinic excess: miosis, salivation, sweating, bronchial constriction, vomiting, and diarrhea. Central nervous system involvement (cognitive disturbance... | 155,520 | medmcqa_train |
Calcium is absorbed from: | All the divalent cations, except Mg++ , are absorbed from duodenum. Mg++ is absorbed from ileum. Calcium is absorbed mainly in duodenum and upper jejunum, not whole of jejunum. | 155,521 | medmcqa_train |
A 62-year-old childless woman noticed a blood-tinged vaginal discharge twice during the past month. Her last menstrual period was 10 years ago. Bimanual pelvic examination shows that the uterus is normal in size, with no palpable adnexal masses. There are no cervical erosions or masses. Her body mass index is 33. Her m... | Postmenopausal vaginal bleeding is a red flag for endometrial carcinoma. Such carcinomas often arise in the setting of endometrial hyperplasia. Increased estrogenic stimulation is thought to drive this process, and risk factors include obesity, type 2 diabetes mellitus, hypertension, and infertility. Choriocarcinomas a... | 155,522 | medmcqa_train |
Aquaporin deficiency cause? | 1. Nephrogenic diabetes insipidus: Aquaporin 2" gene mutation impede the normal functionality of the kidney water channel, which results in the kidney being unable to absorb water. Autosomal recessivemanner. 2. Liddle syndrome: Gain of function of epithelial Na channel (ENaC) 3. Bater syndrome:- Defect in "Na-K-2Cl cot... | 155,523 | medmcqa_train |
Sonographic criteria for diagnosing PCOD includes all except | Presence of 12 or more cysts on ultrasound is diagnostic of PCOD. | 155,524 | medmcqa_train |
Letrozole belongs to which group? | Ans. is 'd' i.e., Aromatase inhibitors Aromatase inhibitorso Aromatase inhibitors are drugs which inhibit the enzyme Aromatase.o Aromatase is an enzyme responsible for the conversion of testosterone (androgens) to estrogens.o This conversion of androgens to estrogens occur in several tissues including ovary, adrenal co... | 155,525 | medmcqa_train |
CAD predisposing factors-a) Homocysteinemiab) ↓ Lipoprotein Bc) ↑ Fibrinogend) ↑ HDLe) ↑ plasminogen activator inhibitors 1 | Homocysteine and Prothrombotic (↑ fibrinogen and ↑ plasminogen activator inhibitors) factors are emerging risk factors for atherosclerosis and coronary heart disease. | 155,526 | medmcqa_train |
Drug of choice for prophylaxis of acute mountain sickness is? | DOC for acute mountain sickness are Carbonic anhydrase inhibitors like Acetazolamide. BEST treatment is to descent down because it occurs due to decreased pO2 at high altitudes. DOC for motion sickness is Hyoscine. | 155,527 | medmcqa_train |
In modern day obstetrics, most common cause of rupture uterus is - | Ans. is 'b' i.e., Previous LSCS scar rupture * Disruption in the continuity of all uterine layers: endometrium, myometrium and serosa anytime beyond 28 weeks of pregnancy is called rupture of uterus.Incidence* 1 in 2000 to 1 in 200 deliveries. Rupture uterus from obstructed labor is becoming less because of improved ob... | 155,528 | medmcqa_train |
A child develops non blanching macules and papules on lower extremities, mild abdominal pain and skin biopsy showed IgA deposition. Most appropriate diagnosis is - | Henoch-Schonlein purpura (HSP), also known as IgA vasculitis, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain. With... | 155,529 | medmcqa_train |
Not true about iodophores ? | Ans. is 'a' i.e., Inorganic compounds Iodine Iodine is more sporicidal than chlorine. Iodine is often used in aqueous and alcoholic solution as skin disinfectant. Aqueous and alcohol based povidone iodine preparations (Betadine) are best and safe skin disinfectants (antiseptics). Iodophores are organic compounds that s... | 155,530 | medmcqa_train |
Giant cells seen in Measles are called? | Lymphoid organs typically have marked follicular hyperplasia, large germinal centers and randomly distributed multinucleated giant cells called Wahin-Finkeldey cells, which have eosinophilic nuclear and cytoplasmic inclusion bodies.Found in the paracoical region of hyperplastic lymph nodes in some patients of measles a... | 155,531 | medmcqa_train |
The term anisometropia indicates | Ans. Refractive error | 155,532 | medmcqa_train |
A 40-year-old man presents to casualty with history of regular and heavy use of alcohol for 10 years and morning drinking for one year. The last alcohol intake was three days back. There is no history of head injury or seizures. On examination, there is no icterus, sign of hepatic encephalopathy or focal neurological s... | Ans. A i.e. Diazepam | 155,533 | medmcqa_train |
The features of uterine contraction in spastic lower segment are all except | Fundal dominance ,which indicates that the intensity is strongest ath the fundus,(not at the lower segment) with a gradual decrease downwards. Refer page no 109 of Text book of obstetrics ,sheila balakrishnan,2 nd edition. | 155,534 | medmcqa_train |
10 year old child with posterior fossa mass. On biopsy following features were seen. What are these dense eosinophilic fibers marked with arrow? | Ans. (a) Rosenthal fibers*Rosenthal fibers are eosinophilic, corkscrew fibers found in pilocytic astrocytoma, the most common primary brain tumor in children. They contain two heat-shock proteins (aB-crystallin and hsp27) as well as ubiquitin.*They are seen in Alexander disease and, pilocytic astrocytoma. | 155,535 | medmcqa_train |
A large baby is born with which complication in pregnancy | Ans. is a i.e. Gestational diabetes | 155,536 | medmcqa_train |
A woman was involved in an accident in which her left leg was crushed and immediate amputation had to be done but you couldn't get a prior consent as the victim was unconscious and the relatives were not available. Later her husband sues you you for doing an amputation without a valid consent. Which of the following se... | Any harm caused to a person in good faith, even without consent is not an offence if the circumstances are such that it is impossible for the person to signify consent and has no guardian from whom it is possible to obtain a consent in time for the thing to be done in benefit as per section 92 IPC. Also know: As per se... | 155,537 | medmcqa_train |
The Rorschach Inkblot test consists of a set of .......... standardized inkblots. These vary in colour, shading, form, and complexity. | Rorschach Inkblot test- Evaluation of Personality, it contains 10 cards having ambiguous inkblot patterns and the subject has to interpret what he is seeing in the card from preselected options Extra Edge Thematic Apperception Test- Test is built on the assumption that people's stories reveal impoant aspects of their n... | 155,538 | medmcqa_train |
Following are acute porphyrias except | The acute porphyrias are acute intermittent porphyria (AIP), variegate porphyria (VP), aminolevulinic acid dehydratase deficiency porphyria(ALAD) and hereditary coproporphyria (HCP). The non-acute porphyrias are X-linked dominant protoporphyria (XLDPP), congenital erythropoietic porphyria (CEP), porphyria cutanea tarda... | 155,539 | medmcqa_train |
Which of the following glycolytic enzymes is used in gluconeogenesis? | Aldolase is the enzyme which catalyses reversible reaction of glycolysis. So this enzyme is utilised in gluconeogenesis. Glucokinase, pyruvate kinase and phosphofructokinase are enzymes which catalyse the reversible reaction of glycolysis. | 155,540 | medmcqa_train |
An organism with sterols in their cell wall is | “Mycoplasma lacks a rigid cell wall and they are bounded by a triple-layered unit membrane that contains sterols.
” Mycoplasma PPLO - by Nocard & Roux • Smallest free-living organism • Gram-negative.highly pleomorphic organism,
stained by Giemsa • Found in the form of elementary bodies & filaments of various size • Fac... | 155,541 | medmcqa_train |
Chest X-ray of an industrial worker exposed to asbestos for 20 yrs shows diffuse appearance of lower lobe with 'comet tail' infarct on PA view. The most likely diagnosis is: | This is a case of mesothelioma secondary to asbestos exposure. The diffuse appearance of lower lobe with 'comet tail' infarct is typical of mesothelioma. Ref: Aicle: The Comet Tail Sign1; 1999 | 155,542 | medmcqa_train |
In starvation, earliest to become depleted - | Ans. is 'a' i.e., CarbohydratesMetabolic alteration during fasting-starvationo he metabolic changes observed in fasting are generally opposite to those described for absorptive (fed) state. In the absence of food, plasma levels of glucose, amino acids, and TGs fall, triggering a decline in insulin secretion and an incr... | 155,543 | medmcqa_train |
Endocrinologic factors associated with recurrent aboion include all of the following except- | Endocrinologic factors associated with recurrent aboion include - Luteal phase insufficiency Diabetes mellitus Hypersecretion of luteinizing hormone (LH) Thyroid disease Insulin resistance Polycystic ovarian syndrome, Hyperprolactinemia Decreased ovarian reserve. | 155,544 | medmcqa_train |
Primitive streak remanants give rise to ? | Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the coccyx (tailbone) and is thought to be derived from the primitive streak. Sacrococcygeal teratomas are benign 75% of the time, malignant 12% of the time, and the remainder are considered "immature teratomas" that share... | 155,545 | medmcqa_train |
Which is safest to be used in asthmatic patients: | C i.e. Chloral hydrate | 155,546 | medmcqa_train |
True statements about the twin-to-twin transfusion syndrome include which of the following? | In the twin-to-twin transfusion syndrome, the donor twin is always anemic, owing not to a hemolytic process but to the direct transfer of blood to the recipient twin, who becomes polycythemic. The recipient may suffer thromboses secondary to hyper-transfusion and subsequent hemoconcentration. Although the donor placent... | 155,547 | medmcqa_train |
Craniotabes is seen in | (A) Rickets # Craniotabes is an abnormal softening or thinning of the skull, although normally present in new boms.> Seen mostly in occipital bone & posterior part of parietal bone.> Bone is soft and has a ping pong ball like feeling on pressing.> The word comes from the German work crani for skull and the Latin word t... | 155,548 | medmcqa_train |
Most common site of March fracture is? | ANSWER: (A) Shaft of 2nd and 3rd metatarsalsREF: Apley's 8th ed p. 757See APPENDIX-68 below for "ALPHABETICAL LIST OF EPONYMOUS FRACTURES"March fracture: stress fracture of second metatarsal APPENDIX - 68Alphabetical List of Eponymous FracturesFractureDescriptionMechanism of injuryAviators fractureFracture neck of talu... | 155,549 | medmcqa_train |
A man, after skinning a dead animal, developed a pustule on his hand. A smear is prepared from the lesion showed the presence of Gram-positive bacilli in long chains which were positive for McFadyean&;s reaction. The most likely aetiological agent is | The person is likely to have anthrax caused by Bacillus anthracis. Anthrax is a zoonotic disease. Infected animals shed in discharges from mouth, nose and rectum, large numbers of bacilli that sporulate in the soil and remain as the source of infection. Bacillus anthracis is a gram-positive bacillus, found singly, in p... | 155,550 | medmcqa_train |
Most common organism associated with cystic fibrosis | Pseudomonas may colonise s of patients with cystic fibrosis and causes recurrent pulmonary exacerbations. Ref : Essential pediatrics,O.P.Ghai,7 th edition,pg no:355 | 155,551 | medmcqa_train |
A newborn presents with mid anterior abdominal wall defect. The House-surgeon is told that this swelling has a characteristic feature i.e spontaneous resolution at age of 5 years by his Professor. What could be the diagnosis? | (Umbilical hernia) (1317-18- CSDT 12th) (1289,1355 B & L 24th) (980-Baily & Love 25th) * Gastroschisis is the most common abdominal defect (726- Nelson 18th) * Ectopia vesicae (exstrophy of the bladder) - Caused by the incomplete development of the infra-umbilical part of the anterior abdominal wall, associated with in... | 155,552 | medmcqa_train |
Most common form of diabetic neuropathy is: September 2009 | Ans. C: Sensorimotor polyneuropathy The overall prevalence of neuropathy is 66% for type I and 59% for type II diabetes.It can be divided into: Symmetric-may present as small-fiber involvement (dysthesia of feet) or autonomic dysfunction (sexual impotence) but often both occur together. Asymmetric neuropathies are divi... | 155,553 | medmcqa_train |
All of the following our the diagnosis of PCOS except | BIOCHEMICAL MARKERS OF PCOD LH level is elevated and/or ratio of LH:FSH is > 3:1 Reversed estradiol:estrone ratio- The estrone level is markedly elevated. SHBG level is reduced. Androstenedione level is elevated. Serum testosterone and DHEA may be marginally elevated. Raised serum insulin level (ratio of fasting glucos... | 155,554 | medmcqa_train |
All of the following are Vitamin-K deficiency features EXCEPT: | Ans. (a) Associated thrombocytopenia with prolonged bleedingRef: Harrison 19th ed. / 96e-8* Vitamin-K is a fat soluble compound. It promotes blood clotting by increasing hepatic biosynthesis of prothrombin and other coagulation factors.* The best sources are green leafy vegetables, liver, cheese, butter and egg yolk. D... | 155,555 | medmcqa_train |
Which is poor man's meat | Pulses (legumes) Pulses comprise a variety of grams, also known as dhals. Most commonly eaten pulses are bengal gram (chana), red gram (tuvar or arhar), green gram (mung) and black gram (urd). Others include lentils (masur), peas and beans including soyabean. Khesari dhal (lathyrus sativus), is consumed in pas of Madhy... | 155,556 | medmcqa_train |
Milian's ear sign is seen is | Erysipelas being a cutaneous condition can spread to ear lobule = Milian's ear sign. | 155,557 | medmcqa_train |
Morbid obesity causes death due to - | The increased moality due to obesity is brought about mainly by the increased incidence of Hypeension and coronary hea diseases . Ref-Park&;s textbook of Preventive and Social Medicine 24th edition. . | 155,558 | medmcqa_train |
A 60-year-old woman visits the ophthalmologist because of eye pain. Tests show that her right eye has an intraocular pressure of 22 mm Hg and her left eye has an intraocular pressure of 25 mm Hg. Which of the following is the most likely cause of eye pain in this woman? | This woman has open-angle glaucoma, which is the most common type of glaucoma. Glaucoma is the second leading cause of blindness worldwide after cataracts. Blindness occurs because of damage to the optic nerve. The high intraocular pressure causes blood vessels and axons of the optic nerve to be compressed at the optic... | 155,559 | medmcqa_train |
The enzyme PeudochoIinesterase acts on: | Suxamethonium is Succinyl choline. Abnormal Psuedocholinestrase is a hereditary defect. In such people S-ch doesn't get metabolized. Usual dose results in prolonged apnoea and paralysis that lasts for hours. Aificial ventilation and blood transfusion are needed to supply Psuedocholinestrase. From padmaja 4th edition Pa... | 155,560 | medmcqa_train |
Foramen Ovale in middle cranial fossa transmits | (B) Mandibular nerve # Foramen ovale;> Mnemonic:> At the base of the skull, the foramen ovale (skull) is in the greater wing of the sphenoid bone in the middle cranial fossa and transmits the mandibular division of the trigeminal nerve, otic ganglion, accessory meningeal artery, lesser petrosal nerve and emissary veins... | 155,561 | medmcqa_train |
All are premalignant conditions of oral cavity except: | All the given options increase the risk of carcinoma of oral cavity but, oral Lichen planus has the least risk as it is Low-risk or Equivocal lesion. Conditions associated with Malignant Transformation HIGH RISK LESIONS Medium-risk Lesions Low-risk or Equivocal Lesions Erythroplakia Speckled Erythroplakia Chronic Hyper... | 155,562 | medmcqa_train |
Most common cause of acute mesenteric ischemia is: | Acute Mesenteric Ischemia :
• Emboli (50%) :
−− Arrhythmia, Valvular disease, Myocardial infarction
−− Hypokinetic ventricular wall
−− Cardiac aneurysm, Aortic atherosclerotic disease
• Thrombosis (25%) : Atherosclerotic disease
• Nonocclusive (5–15%) :
−− Pancreatitis, Heart failure, Sepsis.
−− Cardiac bypass, Burns, ... | 155,563 | medmcqa_train |
Irreversible ototoxicity is caused by - | Ans. is 'a' i.e., Cisplatin "Cisplatin induced hearing loss is usually bilateral and irreversible"Drugs causing ototoxicityA) Vestibular (primarily)o Aminoglycosides o Mustineo Quinidineo Quinineo Chloroquineo Vancomycino Furosemide o Ethacrynic acido Salicylates (high dose)B) Auditory (primarily)o NSAIDso Ethacrynic a... | 155,564 | medmcqa_train |
A 2 years old child comes with one-year h/o of generalised oedema. His B.P. is 107/70mm urine examination shows hyaline cast, proteinuria +++, WBC & RBC are nil. the likely diagnosis is – | It is a case of nephrotic syndrome due to minimal change disease (MCD).
MCD is the most common cause of nephrotic syndrome in children*
Microscopic findings of urine in MCD
Proteinuria
Principally albumin (which is a low molecular weight protein)
High molecular weight proteins are seen in minimal amounts.
This type o... | 155,565 | medmcqa_train |
Which of the following is the most radiosensitive ovarian tumors? | Ans. is a, i.e. DysgerminomaRef: Bailey & Love 24th/ed, p22l"Below the age of 20 years 60% of the tumors are of germ cell origin and in girls under the age of 10 years almost 85% are of germ cell origin and are invariably malignantIn females with HNPCC gene mutation along with BSO, hysterectomy should also be done as t... | 155,566 | medmcqa_train |
Hunters syndrome due to deficiency of - | Ans. is 'a' i.e., Iduronate sulfatase (Ghai 7th/ep. 639) o Iduronate sulfate sulfatase def. - Hunter syndrome o Hexosaminidase dediciencv seen in Tay-sachs disease o Glucocerebrosidase def. - Gaucher disease | 155,567 | medmcqa_train |
Simple Basal media is? | Ans. is 'a' i.e., Simple nutrient agar A culture medium is a liquid or gel designed to suppo the growth of microorganism or cell. A culture medium may be liquid or solid. A culture medium may be? i) Basal (Simple) media This is simple with no added ingredients. It may be liquid ( peptone water) or solid (Nutrient agar)... | 155,568 | medmcqa_train |
A child presents with hepatomegaly and bilateral lenticular opacities. Which of the following enzyme deficiency will NOT cause such features? | Inability to metabolize galactose occurs in the galactosemias, which may be caused by inherited defects of galactokinase, uridyl transferase, or 4-epimerase, though deficiency of uridyl transferase is best known. Galactose is a substrate for aldose reductase, forming galactitol, which accumulates in the lens of the eye... | 155,569 | medmcqa_train |
Which of the following has fibromuscular stroma ? | The prostatic pa of the urethra develops from the pelvic (middle) pa of the urogenital sinus (endodermal origin). Endodermal outgrowths arise from the prostatic pa of the urethra and grow into the surrounding mesenchyme. The glandular epithelium of the prostate differentiates from these endodermal cells, and the associ... | 155,570 | medmcqa_train |
A 60-year-old female complains of dry mouth and a gritty sensation in her eyes. She states it is sometimes difficult to speak for more than a few minutes. There is no history of diabetes mellitus or neurologic disease. The patient is on no medications. On exam, the buccal mucosa appears dry and the salivary glands are ... | (Braunwald, 15/e, pp 1947-1949.) The complaints described are characteristic of Sjogren syndrome, an autoimmune disease with presenting symptoms of dry eyes and dry mouth. The disease is caused by lymphocytic infiltration and destruction of lacrimal and salivary glands. Dry eyes can be measured objectively by the Schir... | 155,571 | medmcqa_train |
A girl presented with symptoms of pharyngitis. Group A hemolytic pharyngitis is due to? | Local infection is the most common cause of inflammation of pharyngeal structures or acute pharyngitis. Group A beta-hemolytic streptococcus is a common causative organism in both pharyngitis and tonsillitis. Local infection and inflammation cause lymph node enlargement, swelling, erythema, and pain. | 155,572 | medmcqa_train |
Bad dreams are a rare adverse effect of which of the following drug? | Erectile dysfunction, impotence, bad dreams and hallucinations can be seen with beta blockers REFERENCES: KDT 6th ed pg 135-140 Goodman Gillman 12th ed pg 280-285 | 155,573 | medmcqa_train |
Lowest chance of recipient failure in transplant is seen in: | Ans. (b) IsograftRef: Bailey 26th ed, page 1426* Isograft: A graft between identical donor such as identical twin* Hence the rejection rate is the lowest | 155,574 | medmcqa_train |
A patient presented with thunder clap headache followed by unconsciousness with pregressive 111 ranial nerve palsy. Likely diagnosis is | davidson's principles and practices of medicine 22nd edition. *85% of SAH are caused by saccular or berry aneurysm arise from bifurcation of cerebral aeries *SAH typically presented with a sudden ,severe ,thunderclap headache (often occipital) , which lasts for hours or even days,often accompanied by vomitting , raised... | 155,575 | medmcqa_train |
A new born child developed respiratory depression in neonatal ward. Which of the following drug is the cause - | Ans is 'a' i.e., Opioids | 155,576 | medmcqa_train |
TRUE regarding chi square test is | Ref: Parks 23rd edition pg 852 Chi-square test offers an alternate method of testing the significance of difference between two propoions. Advantage: it can also be used when more than 2groups are to be compared. | 155,577 | medmcqa_train |
Necrotizing epitheloid cell granulomas are seen in all, except - | Mycobacterium leprae infection leads to formation of non caseating granulomas, which is not necrotising.the lesions are erythematous type Basic Pathology, Robbins. Page no.: 56 | 155,578 | medmcqa_train |
Splenic infarction is associated with | . | 155,579 | medmcqa_train |
Treatment of dacryocystitis in three months old child- | *Spontaneous recanalization of obstructed nasolacrimal duct occurs during first 6-8 weeks and sometimes after 6-12 months in 90%of infants. Therefore up to 9-12months only massage and antibiotic drops are indicated. After the age of 12 months high pressure syringing is indicated. | 155,580 | medmcqa_train |
Which of the following is a killed vaccine ? | Ans. is 'd' i.e., Japanese encephalitis Live attenuated Inactivated or killed Immunoglobulins Bacterial Bacterial Human normal Subunit Vaccines BCG Typhoid Hepatitis A,B Hepatitis B Typhoid oral Cholera Measles Typhoid Vi antigen Viral Peussis Rabies Toxoids Oral Polio(Sabin) Meningitis Tetanus Diphtheria Yellow fever ... | 155,581 | medmcqa_train |
Malignancy in a multinodular goiter is most often:- | Follicular ca: - Seen in iodine deficient areas - M/C malignancy in long standing goiter - M/c malignancy in multinodular goiter Papillary ca: - Seen in iodine sufficient areas - M/C thyroid malignancy Anaplastic ca: - Rare; m/c seen in females - Usually seen in 7th - 8th decade of life Medullary ca: - Arise from Paraf... | 155,582 | medmcqa_train |
Dohle bodies are seen in which of the following? | Döhle bodies are basophilic leukocyte inclusions located in the peripheral cytoplasm of neutrophils. They are said to be remnants of the rough endoplasmic reticulum.
Conditions associated with Dohle bodies:
Burns
Infections
Physical trauma
Neoplastic diseases
Wissler’s disease
May-Hegglin anomaly (seen in neutrophil, ... | 155,583 | medmcqa_train |
Diagnosis of TB acc to DOTS? | 1 or 2 positives put of 2 sputum smear is considered as smear positive TB Ref: PARK&;S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 23rd edition pg 429 | 155,584 | medmcqa_train |
A person developed anterior wall MI and died within 2 hours of onset of the symptoms. The pathological autopsy of the hea and observation of the involved myocardium under light microscopy, is underway. What will the finding be, if any? | Though usually no finding may be present in the 1st four hours, there may be waviness of myocytes and on electron microscopy disruption of the sarcolemma and mitochondrial amorphous densities may be present. Coagulative necrosis begins only after 4 hours and neutrophilic infiltration occurs only after 12 hours. Here th... | 155,585 | medmcqa_train |
Facilitation of flexor muscle tone is by | Rubrospinal tract facilitates flexor muscle and inhibits extensor muscles.
Vestibulospinal tract facilitates extensor muscle of lower limb and inhibits flexors. | 155,586 | medmcqa_train |
Chromosomal number of primary cnermatecvte is | Ans. is a i.e. 44XY | 155,587 | medmcqa_train |
50 yr old female presented with lump in right breast. She was diagnosed having Luminal A carcinoma. All are true about this cancer except ? | Luminal A breast cancer Seen in elderly females M/c subtype ER/ PR positive Her 2 /Neu negative Low proliferation rate Ki 67 : low Best prognosis among subtypes Responsive to hormonal chemotherapeutic agents like tamoxifen and aromatase inhibitors, Respond poorly to non- hormonal chemotherapy drugs like paclitaxel. Imm... | 155,588 | medmcqa_train |
True about benzodiazepines ? | Ans. is 'c' i.e., Lorazepam is shoer acting than temazepam Lorazepam has VA 10-20 hours, while Temazepam has VA 10-40 hours. About other options BZDs do not increase or decrease the release of GABA, they bind on GABAA receptors and increase Cl- conductance - GABA facilitatory action. Flumazenil (not atropine) is the an... | 155,589 | medmcqa_train |
Curling ulcer is seen in - | Answer is 'a' i.e. Burns Curling ulcer is seen in Burn Cushing ulcer is seen in head injury. | 155,590 | medmcqa_train |
Pain is carried to | Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception. The dorsal horn provides numerous potential targets for the development of novel analgesics and is thought to undergo changes that contribute to the exagger... | 155,591 | medmcqa_train |
Activation of the baroreceptor reflex | The baroreceptors are stretch receptors in the walls of the heart and blood vessels. The carotid sinus and aortic arch receptors monitor the arterial circulation. The baroreceptors are stimulated by distention of the structures in which they are located, and so they discharge at an increased rate when the pressure in t... | 155,592 | medmcqa_train |
Cyclic trend is shown by- | Ans. is 'd' i.e., All of the above Cyclic trend* Some diseases occur in cyclic spread over a short period of time which may be week, days, months or years.* This is due to naturally occuring variation in herd immunity.* A build up of susceptible is again required in the herd before there can be another attack.* It may ... | 155,593 | medmcqa_train |
Which among the following is not a feature of Unhappy triad of O' Donoghue? | Ans. is 4d' i.e., Fibular collateral ligament injury [Ref: Apleys 9k/ep. 876}o The most common mechanism of ligament disruption of knee is adduction (valgusj, flexion and internal rotation of femur on tibia which usually occur in sports in which the foot is planted solidly on the ground and leg is twisted by rotating b... | 155,594 | medmcqa_train |
The phenomenon of suspended animation may be seen in - | Suspended animation may be seen in electrocution, drowning, cholera, after anesthesia, shock, sunstroke, cerebral concussion, narcotic poisoning, new born infants and yogis/voluntary. | 155,595 | medmcqa_train |
Endolymph is rich in ? | Ans. is 'd' i.e., K+Fluid in inner ear There are two main fluids in the inner ear : -(i) Perilymph (ii) EndolymphPerilymphIt resembles ECF and is rich in Nu+ ions. It fills the space between bony and the membranous labyrinth, i.e., Scala vestibuli and scala tympani. It communicates with CSF through the aqueduct of Coch... | 155,596 | medmcqa_train |
A 30 year old woman with a bad obstetric history presents with fever. The blood culture from the patient grows gram-positive small to medium coccobacilli that are pleomorphic, occurring in sho chains. Direct wet from the culture shows tumbling motility. The most likely organism is - | . Ans. is 'a' i.e., Listera monocytogenes . The impoant clues in this question are . Organisms are gram positive coccobacilli . Organisms are pleomorphic and occuring in sho chains. . There is tumbling motility. . All these are the features of Listeria monocytogens. . Corynebacteria are gram positive bacilli (not cocco... | 155,597 | medmcqa_train |
Clinical goal for prevention of coronary hea disease aims at lowering the ratio of cholesterol/ HDL below: September 2011 | Ans. C: 3.5 A ratio of less than 3.5 has been recommended as a clinical goal for CHD prevention Total cholesterol Desirable: less than 200 milligrams (preferably 180) Borderline: 200-239 milligrams High: 240 milligrams and above LDL cholesterol Desirable: less than 130 milligrams Borderline-high: 130-159 milligrams Hig... | 155,598 | medmcqa_train |
All of the following statements regarding jaundice in a newborn are true, Except ________ | A rapidly rising unconjugated bilirubin concentration, or absolute levels >340 mmol/L (20 mg/dL), puts the infant at risk for bilirubin encephalopathy, or kernicterus. Under these circumstances, bilirubin crosses an immature blood-brain barrier and precipitates in the basal ganglia and other areas of the brain. The con... | 155,599 | medmcqa_train |
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