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Shock lung is characterized by
ref Robbins 7/r p715,9/e p134 Harrison 17/e p1680_1681 The cellular and tissue effects of shock are essentially those of hypoxic injury (Chapter 1) and are caused by a combina- tion of hypoperfusion and microvascular thrombosis. Although any organ can be affected, brain, hea, kidneys, adrenals, and gastrointestinal tra...
155,700
medmcqa_train
Most common muscle involved in Tropical pyomyositis
Tropical pyomyositis is caused by S.Aureus which mainly involves Quadriceps > Gluteus.
155,701
medmcqa_train
Visual analog scale is a -
Ans. is 'a' i.e., Pain scale Visual analog Scaleo The visual analogue scale or visual analog scale (VAS) is a psychometric response scale which can be used in questionnaires.o It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured,o When responding to a VAS item, res...
155,702
medmcqa_train
Type of pneumonia in P. jiroveci:
Ans. b. Interstitial pneumonia
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Which of the following neurotransmitter has an inhibitory control over the GnRH neurons before the onset of pubey?
Before the onset of pubey, the GnRH neurons are under the inhibitory control of GABA. Gamma amino butyric acid is a dominant inhibitory neurotransmitter in the hypothalamus. Inhibition of GnRH neurons by GABA is mediated Glutamergic neurons. A reciprocal innervations between GABAergic and Glutamergic neurons are found....
155,704
medmcqa_train
A middle aged female presents with chronic pain in right side of abdomen with intermittent fever. Clinical examination revealed mild hepatomegaly and hence a contrast enhanced CT abdomen was performed. Based on the imaging characteristics of this focal lesion the most likely diagnosis is?
Ans. B. Hydatid cystThe Portal phase CT demonstrates a large cystic structure with a discrete wall, separated internal membranes and several 'daughter cysts'This is an infection of the liver with Echinococcus granulosus, a parasitic tapeworm presents worldwide and transmitted from sheep, foxes and other wild animals to...
155,705
medmcqa_train
Millard Gubler syndrome includes the following except
Millard-Gubler syndrome (MGS) is one of the classical brainstem-crossed syndromes caused due to a unilateral lesion in ventral pons, manifesting as ipsilateral palsy of CN VI and VII with contralateral hemiplegia Ref Harrison20th edition pg 2234
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C. trachomatis is a well-known cause of venereal disease. This organism is also implicated in which of the following?
Trachoma has been the greatest single cause of blindness in the world. Chlamydia trachomatis is the most common cause of sexually transmitted disease in the United States and is also responsible for the majority of cases of infant conjunctivitis and infant pneumonia.
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Prostaglandins are produced by ?
Ans. is 'd' i.e., All of the above
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All of the following statements about Parvovirus B -19 are TRUE, EXCEPT:
Parvovirus B-19 causes a infection called Erythema infectiosum or Fifth disease. Around 50-70% cases are around 5-15 years of age. Transmission from mother to fetus is around 15-30%. It causes, anemia, aplastic crisis, rashes, ahralgia, rarely hydrops fetalis. Ref: Kliegman, Behrman, Jenson, Stanton (2008), "Nelson tex...
155,709
medmcqa_train
'Pie in the sky' visual field defect seen in lesions of:
A. Left Hemianopia Left optic nerve lesion B. Bitemporal Hemianopia Optic chiasm lesion C. Right Nasal Hemianopia Outer optic tract lesion Internal carotid aery thrombus D. Right Homonymous Hemianopia Optic tract lesion E. Right Superior Quadrantanopia Meyer's Loop lesion Left temporal lesion F. Right Inferior Quadrant...
155,710
medmcqa_train
What is true regarding Barret's esophagus:
Answer is B (Premalignant condition) Barret's oesophagus is a premalignant condition with increased risk of adenocarcinoma. Barret's esophagus is more common in males More common in males (Males > Females)0 More common in White (Whites > Blacks)e More common with increasing ageU Barret's metaplasia once established doe...
155,711
medmcqa_train
Gas shadow in hea and vessels are seen in
Robe sign - the presence of a gas shadow within the hea or the greater vessels, seen in cases of fetal death in utero.It is a rare sign caused by postmoem blood degeneration, usually seen 1-2 days after death; and may be seen as early as 12 hours(Ref: Diagnostic Ultrasound by Carol M. Rumack, Stephanie R. Wilson, J. Wi...
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medmcqa_train
Latte's crust of blood stain is used to detect: NEET 14
Ans. Blood group
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The cause of fetal death in ectopic pregnancy is postulated as:
Ans. is a, i.e. Vascular accidentRef Williams Gynae 1/e, p 158Ectopic pregnancy is the leading cause of early pregnancy related deaths.Most common cause of death in ectopic pregnancy is tubal rupture - severe hemorrhage - death.Ectopic pregnancy can have 2 outcomes:1. Tubal abortion - M/C outcome. It is most common out...
155,714
medmcqa_train
When a stretch reflex occurs the muscles that antagonize the action of the muscle involved relaxes. This phenomenon is known as:
Reciprocal innervation is a phenomenon in which, when a stretch reflex occurs the muscles that anotogonize the action of the muscle involved relaxes. The pathway mediating this effect is bisynaptic. Golgi bottle neurons (inhibitory interneurons) are involved in this phenomenon. Ref:Ganong's Review of Medical Physiology...
155,715
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Jaw tightness is typically seen in:
Answer is C (Giant Cell Aeritis): Jaw Claudication (law Tightness) is a typical manifestation of Temporal aeritis or Giant cell aeritis.
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Salpingitis/Endosalpingitis is best confirmed by:
Ans. is a, i.e. Hysteroscopy and laparoscopyRef: Shaw 15th/ed, p451; William's Gynae 1st/ed, p74; Gynecology by Ostrzenski (Lippincott Williams 2(X)l/282); Dutta Gynae 6th/ed, p130Laparoscopy is considered the "gold standard". While it is the most reliable aid to support the clinical diagnosis but it may not be feasibl...
155,717
medmcqa_train
Lymes disease all are true except
Polymorphonuclear leucocytosis in C.S.F. suggests meningeal involvement Spread of infection and immune response in Lyme disease Lyme disease is caused by Borrelia Burgdorferi. Borrelia burgdorferi is transmitted to humans the bite of ixodes tick vector. Borrelia burgdorferi is inoculated in the skin, where local replic...
155,718
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Approximate time, at the end of which the quantity of ATP within ischemic cardiac myocytes is reduced to 10% of the original is
Metabolic changes slow as the duration of ischemia increases. Irreversibly injured myocytes exhibit (a) very low levels of ATP (less than 10% of control); (b) cessation of anaerobic glycolysis; (c) high levels of H+, AMP, INO, lactate, and alpha GP; (d) a greatly increased osmolar load; (e) mitochondrial swelling and f...
155,719
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Aluminium phosphide poisoning - all true except
inhibits cytochrome a oxidase Aluminium phosphide produces phosphine gas on coming in contact with moisture which inhibits cytochrome c oxidase (and not cytochrome a oxidase). Sub-endocardial infarction and esophageal strictures both have been described with ALP poisoning (Ref: various journals on web) Aluminium phosph...
155,720
medmcqa_train
The small intestine secretes various triglyceride-rich lipoproteins, but the liver secretes only
Although both chylomicrons and VLDLs are triglyceride-rich lipoproteins, the liver, unlike the small intestine, produces only VLDLs. LDLs and HDLs are not triglyceride-rich lipoproteins. Chylomicron remnants are generated in the circulation by the metabolism of chylomicrons.
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Features not seen in Cushing's Syndrome is :
Answer is A (Hypoglycemia): Cushing's syndrome is characterised by Hy perglycemia. Increased hepatic gluconeogenesis and insulin resistance causes increase in blood glucose. Hypeension is common, & emotional changes may be profound, ranging from irritability & emotional liability to severe depressions, confusion or eve...
155,722
medmcqa_train
Fulminant hepatitis is most commonly associated with which type of hepatitis -
Ans. is 'b' i.e., Hepatitis B Fulminant hepatits* The most feared complication of viral hepatitis is fulminant hepatitis (massive hepatic necrosis); fortunately, this is a rare event.* Fulminant hepatitis is primarily seen in hepatitis B and D, as well as hepatitis E, but rare fulminant cases of hepatitis A occur prima...
155,723
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Blood samples for glucose estimation are collected in fluoride bulbs/tubes as fluride prevents glycolysis byinhibition of
Ans. a (Enolase) (Ref. Harper's Illustrated 26th ed., 137; 27th/Ch. 18)ENOLASE# The step of glycolysis catalyzed by enolase involves dehydration, forming phosphoenolpyruvate.# Enolase is inhibited by fluoride.- To prevent glycolysis in the estimation of glucose, blood is collected in tubes containing fluoride.# The enz...
155,724
medmcqa_train
Which is a communicating hydrocele?
Funicular hydrocele Communicating hydrocele: (a) Funicular hydrocele, and (b) Congenital hydrocele. a. Funicular Hydrocele: Processus vaginalis remains patent up to the top where it is shut off from the tunica vaginalis. Diagnostic features: (i) The swelling is inguinal rather than scrotal. (ii) The test is it can be f...
155,725
medmcqa_train
Which of the following structures is most significant in resisting hyperextension of the hip joint?,
The Iliofemoral Ligament resist both hyperextension and lateral rotation at the hip joint. The Pubofemoral ligament reinforces the joint inferiorly and limits extension and abduction. The Ischiofemoral ligament reinforces the joint posteriorly and limits extension and medial rotation. The Gluteus Maximus muscle extends...
155,726
medmcqa_train
Rhinophyma occurs as complication of
Rosacea:-Chronic skin infection characterised by symptoms of facial flushing and a spectrum of signs including erythema, telangiectasia,coarseness of skin and inflammatory papulopustular lesion.Features:-1. Red papules and pustules on nose ,forehead,cheeks and chin.2. Frequent flushing 3. Aggravated by sun exposure,foo...
155,727
medmcqa_train
In CuT 200, the number stands for:
Ans: A (Surface...) "The number included in the names of the devices refer to the surface area (in sq, mm) of the copper on the device. Park 21st/459 IUDs: Review of Facts# CuT-200 B being used in India , under the national family welfare programme,Later CuT 380A is introduced in the programme.# Studies have shown that...
155,728
medmcqa_train
Chauffers fracture involves what ?
Chauffeur&;s fracture, also known as Hutchinson fracture, is a type offracture of the forearm, specifically the radial styloid process. The injury is typically caused by compression of the scaphoid bone of the hand against the styloid process of the distal radius. Ref : essential ohopaedics maheshwari and mhaskar 9th e...
155,729
medmcqa_train
"French paradox" is -
The French paradox is a catchphrase first used in the late 1980s, that summarizes the apparently paradoxical epidemiological observation that French people have a relatively low incidence of coronary hea disease (CHD), while having a diet relatively rich in saturated fats,in apparent contradiction to the widely held be...
155,730
medmcqa_train
A 64-year-old man with heart failure is recently started on 80 mg/day of furosemide. He now feels weak and tired, but notes that his heart failure symptoms have improved. There is no change in his urine output and he gets a good diuretic response every time he takes his furosemide.Select the characteristic ECG findings...
Hypokalemia results in prolongation of the QU interval. The delayed repolarization in hypokalemia is best expressed at QU rather than QT prolongation since it can be difficult to separate the T wave from the U wave. In severe cases, the ST segments become depressed. Quinidine, even in therapeutic doses, can cause simil...
155,731
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Diagnostic criteria for Bulimia nervosa are all EXCEPT
(B) Presence of other psychiatric disorders # BULIMIA NERVOSA (BN) is an eating disorder characterized by eating binges typically followed by efforts to purge calories through self-induced vomiting, laxative and/or diuretic abuse, prolonged fasting, or excessive exercise. Fear of weight gain leads to the characteristic...
155,732
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Prolonged exposure to noise levels greater than the following can impair hearing permanently -
Repeated or continuous exposure to the noise around 100 decibels may result in a permanent hearing loss; inner ear damage may vary from minor changes in the hair cells to complete destruction of the organ of Coi. Park's Textbook of Preventive and Social Medicine, 22nd edition, Page No. 689
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Defect in type II hyperlipidemia
Familial hypercholesterolemia (type Ha) is due to deficiency of functional LDL receptors as a result of different types of mutations.
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What is meant by suppositious child -
Ans. is 'c' i.e., Child rear up by a woman & She claims the child Suppositious child Suppositious child means a factitious child. o Women may pretend pregnancy as well as delivery & later produces a child as if it is her own. She may substitute a living male child for a dead child or for a living female child born of h...
155,735
medmcqa_train
Corneal endothelial cell count is done by -
Ans. is 'a' i.e., Specular microscopy o Specular microcopy is used for corneal endothelial density.Important corneal examinationsCsed foro Keratometry. Comeal topographyCurvature of corneao Specular microscopyCorneal endothelial densityo Slit lampCorneal opacityo PachymeterThickness of corneao Placido's discCorneal she...
155,736
medmcqa_train
All are true about Amoebic liver abscess except: March 2007
Ans. B: Alcoholics are susceptible to develop amoebic liver abscess Amebic liver abscess is the most frequent extraintestinal manifestation of Entamoeba histolytica infection. This infection is caused by the protozoa Ehistolytica, which ascends the poal venous system. The right lobe (posterior superior quadrant) of the...
155,737
medmcqa_train
All of the following conditions are associated with primary amenorrhea except:
Ans. is b, i.e. Stein-Leventhal syndromeRef: Shaw 15th/ed, p284-285The Stein-Leventhal Syndrome also known as Polycystic Ovarian Disease (PCOD) is an important cause of Secondary Amenorrhea in young women.Testicular Feminizing syndrome, Turners syndrome and Mayer Rokitansky Kuster Hauser syndrome are causes of Primary ...
155,738
medmcqa_train
What is the drug of choice for Obsessive Compulsive Disorder?
Ans. (B) Fluoxetine(Ref: Harrison 17/e p2715; CMDT 2010/943; KDT 8/e p492)SSRIs are drug of choice for most of the neurotic disorders including OCD.
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The drug causing curare like effects are all except
Refer KDT 6/e p 346 Drugs causing curare like effect are Aminoglycosides Polypeptide antibiotics Tetracycline Clindamycin, lincomycin
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Investigation of choice on Meckel's Diveicula in pediatric age group is
In case of children 99mTc-peechnetate is preferentially taken up by the mucus secreting cells of gastric mucosa and ectopic gastric tissue in Meckel's Diveicula. In adults less ectopic gastric tissue is seen so the test is not much accurate in adults Ref: Sabiston 20th edition Pgno :1285
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Os trigonum is which type of epiphysis ?
C i.e. Atavistic
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Wolff-chaikoff effect is -
Ans. is 'c' i.e., Reduced thyroxine synthesis by iodides Iodine and Iodideso Iodine is the fastest acting thyroid inhibitor.o Most important action is inhibition of hormone release (thyroid constipation)\ but all facets of thyroid synthesis may be affected.o Excess iodide inhibits its own transport in thyroid cells and...
155,743
medmcqa_train
Growth of virus in embryonated egg, eggs are incubated for -
Ans. is 'c' i.e., 5-12 days "For virus isolation, feile chicken eggs are incubated for 5-12 days, and a viral Suspension or suspected virus - containing" tissue is injected into the fluid of the egg.
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Which of the following is primarily a bactericidal drug?
Aminoglycosides: Streptomycin, Gentamicin, Amikacin, Neomycin, etc. are considered as bactericidal drugs.
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N K cell shows presence of -
Ans. is 'b' i.e., CD 16 o NK cells have CD-56 and CD-16 on their surface.
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A radiologist notes the presence of fine, radiographically dense crystals in the tissues of a knee joint. This patient most likely has which of the following types of ahropathy?
Radiographically dense calcium pyrophosphate dihydrate (CPPD) crystals are deposited in cailage and joint soft tissues in pseudogout, which can involve the knees, wrists, elbows, shoulders, or ankles. If the patient is asymptomatic because the deposition is primarily within cailage, the condition is sometimes called ch...
155,747
medmcqa_train
All are seen with Pneumocystis carini in AIDS except:
In addition to pneumonia, a number of other clinical problems have been repoed in HIV-infected patients as a result of infection with P. jiroveci as:- Otic involvement may be seen as a primary infection, presenting as a polypoid mass involving the external auditory canal. In patients receiving aerosolized pentamidine f...
155,748
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All of the following aeries are common sites of occlusion by a except:
Answer is D (Marginal aery)
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von Willebrand disease is a defect of
Primary hemostasis: the formation of the platelet plug.Disruption of the endothelium exposes subendothelial von Willebrand factor (vWF) and collagen, which promote platelet adherence and activation. Activation of platelets results in a dramatic shape change as well as the release of secretory granules. Within minutes t...
155,750
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All true about sodium Thiopentone except -
Thiopentone is ultrasho acting barbiturate. Thiopentone does not produce analgesia and may even produce antianalgesia by reducing the pain threshold. Thiopentone has rapid onset of action (within 30 s) due to high lipid solubility and high non ionized fraction (60%). And ultra-sho duration of action (within 20 mins) du...
155,751
medmcqa_train
Which of the following antihypeensive inhibits vesicular uptake of NA -
Ans. is 'c' i.e., Reserpine o Reserpine inhibits vesicular uptake of NA, 5-HT & DA --) monoamines are gradually depleted and degraded by MAO.
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Gastric emptying is decreased by all of the following EXCEPT:
Acidity of the chyme, hyper- or hypo-osmolarity of the duodenal contents, irritation of the duodenal mucosa, protein or fat breakdown products in duodenum are the factors sensed by the duodenal receptors. Gastric emptying will then be decreased, by a combination of neural and hormonal signals. Neural signals would be e...
155,753
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Cystic supratentorial tumor is?
Ans. is 'a' i.e. Craniopharyngioma * Craniopharyngioma is supratentorial slow growing cystic tumor.Other options* Ependymoma can both supra and infratentorial.* Medulloblastoma is an infratentorial tumor.
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Microbiologic studies on a gram-positive coccus isolated from a skin abscess demonstrate a positive catalase test and a positive coagulase test. This is most consistent with which of the following organisms?
All of the organisms listed are gram-positive cocci. The positive catalase test excludes the Streptococci, S. pyogenes, and S. pneumoniae. Of the Staphylococci, only S. aureus has a positive coagulase test. S. epidermidis and S. saprophyticus are coagulase-negative Staphylococci. Ref: Ray C.G., Ryan K.J. (2010). Chapte...
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True about incest is: Karnataka 11
Ans. Not punishable in India
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Pneumocytes are cells found in epithelial lining of:
PneumocytesTwo types of pneumocytes contribute to the maintenance of the alveoli of the lungsType I pneumocytes and Type II pneumocytes.These cells function to aid in gas exchange, secretion of pulmonary surfactant, and self-regeneration
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Which one of the following is not a feature of liver histology in Non cirrhotic poal fibrosis (NCPF) ?
Ans. is 'd' i.e., Bridging fibrosisFibrosis bridging one poal tract to another (bridging fibrosis) is not seen.Pathology : o Non cirrhotic poal fibrosis is primarily a vascular disorder of the liver characterized by fibrous intimal thichening of the poal vein or its branches in patients with non cirrhotic protal hypeen...
155,758
medmcqa_train
Which of the following is a harmful: March 2009
Ans. A: Alpha Paicle The radiation one typically encounters is one of four types: alpha radiation, beta radiation, gamma radiation, and X-radiation. Neutron radiation is also encountered in nuclear power plants and high-altitude flight and emitted from some industrial radioactive sources. A Alpha radiation is a heavy, ...
155,759
medmcqa_train
Drug of choice for treatment of leptospirosis is:
Penicillin is the drug of choice for treatment of leptospirosis. Other drugs used are tetracycline and doxycycline. Ref: Park 21st edition, page 267.
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A 42 year old paraplegic woman has a neurogenic bladder and requires an indwelling urinary catheter. She develops a urinary tract infection and is seen by a urologist, who orders abdominal x-rays and an intravenous pyelogram. The radiographic studies demonstrate a very large stone that fills and follows the contours of...
Staghorn calculi, such as described in the question, are associated with infection by urea-splitting bacteria (notably Proteus species) and are composed of magnesium ammonium phosphate (struvite). They are more common in women than men, and are far more common in patients requiring chronic bladder catheterisation. Calc...
155,761
medmcqa_train
Temporary and permanent removed by –
Permutit method (Base exchange process) can remove both permanent and temporary hardness.
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Puerperal pyrexia is defined as a temperature of more than:
A temperature of 38.0degC (100.4degF) or higher--in the puerperium. Causes Genital tract infection Breast engorgement Urinary infections Wound infection Perineal lacerations infection Respiratory complications Predisposing factors Home bih in unhygienic conditions, low socioeconomic status poor nutrition primiparity an...
155,763
medmcqa_train
CB 1 antagonist used in smoking cessation is ?
Ans. is 'b' i.e., Rimonabant Rimonabant A selective cannabinoid receptor-1 (CB-1) antagonist which is being tried as antismoking and antiobesity drug.
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Which of the following is not true about the difference between congenital cataract surgery and senile cataract surgery?
The energy used in phacoemulsification is lesser as compared to the senile cataract. Congenital Cataract Surgery Treatment of choice: Lens aspiration by manual SICS technique or by phaco-emucification technique. Lensectomy can be done in total cataract with retinal detachment or ROP or any congenital retinal condition ...
155,765
medmcqa_train
What is the ideal treatment for a 55-years-female with Simple hyperplasia of the endometrium with Atypia?
Management of Atypical Endometrial Hyperplasia: "Hysterectomy is the best treatment for women at any age with atypical endometrial hyperplasia because the risk of concurrent subclinical invasive disease is high." Williams Gynae 1st ed p 691 "In presence of atypia, response to progesterone therapy is poor and the relaps...
155,766
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Ehrlich phenomenon is seen in
The difference between the amount of diphtheria toxin that will exactly neutralize one unit of antitoxin and that which, added to one unit of antitoxin, will leave one lethal dose free is greater than one lethal dose of toxin; i.e., it is necessary to add more than one lethal dose of toxin to a neutral mixture of toxin...
155,767
medmcqa_train
"Boiler's notch" is suggestive of ?
Boiler notch/Acoustic dip is seen in Noise induced hearing loss NIHL Boiler notch at 4000Hz Notch is seen in BC curve AC curve notch are insignificant Maximum seen at 3000-6000Hz Sound causing maximum NIHL 2000-3000Hz Stereocilia of Outer hair cells are first to be affected
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A 40 year old woman presents with a three day history of irritation, pain, and watery discharge of her left ear. She has just returned from holiday, where she admits to using her towel, aificial nails, and ear buds to try to allete itching in her ear. What is the likely diagnosis?
Inflammation of the ear canal with or without infection is the charecteristic of acute otitis externa. If symptoms are recurrent or if they last longer than three months, the condition is classed as chronic otitis externa. Acute otitis externa can also be classified according to its cause. These are split into three ma...
155,769
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Following anterior dislocation of the shoulder, apt develops weakness of flexion at the elbow and lack of sensation over the lateral aspect forearm; nerve injured is -
The most common complication of anterior dislocation of the shoulder is axillary (circumflex) nerve injury. There is consequent paralysis of the deltoid muscle, with a small area of anaesthesia at the lateral aspect of the upper arm. However, in this question, the sensation is lost on the lateral aspect of the forearm ...
155,770
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Heavy smoker for elective hernia repair, smoking should be stopped before how much period?
Ans. is 'd' i.e., 6-8 weeksRef: Postgraduate anaesthesia p. 786'Limited prospective data suggest that cessation for at least 6-8 weeks preoperative is necessary to decrease the incidence of pulmonary complication."
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A nerve injured in radical neck dissection leads to loss of sensation in medial side of the arm, nerve injured is:-
Nerve injured in radical neck dissection leads to loss of sensation in medial side of the arm, nerve injured is medial cutaneous nerve of arm. The medial cutaneous nerve of arm supplies the skin of the medial aspect of the arm. It is the smallest branch of the brachial plexus, and arises from the medial cord and contai...
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Inward flow of Na+ in hea leads to
Entry of Na ions into cardiac cell leads to depolarisation. (REF TEXTBOOK OF MEDICAL PHYSIOLOGY GEETHA N 2 EDITION, PAGE NO 52)
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Apoplexy is: DNB 08
Ans. Sudden onset of bleeding in the brain
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A 17-year old male complains of recurrent episodes of cough, wheezing and shoness of breath paicularly at night for the last 3 days. His sibling has a history of similar symptoms. A Skin test with pollen produces immediate wheal and flare. The laboratory finding most consistent with his clinical findings would be
Atopy is the major risk factor for asthma.Patients with asthma commonly suffer from other atopic diseases,paicularly allergic rhinitis and atopic dermatitis.Eosinophilic infiltration of airways along with peripheral eosinophilia is a characteristic feature seen in asthmatic patients.There will also be elevated total se...
155,775
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HLA complex in humans is located on?
Ans. b (Short arm of chromosome 6). (Ref Harrison's medicine 16th ed. 1930)MAJOR HISTOCOMPATIBILITY COMPLEX (MHC)# MHC is a gene cluster of various loci grouped together on a single locus.# The MHC of humans, or the HLA complex, is located on the short arm of chromosome 6 approximately 32 CM from the centromere.# The l...
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medmcqa_train
With which of the following receptors theophylline has an antagonist interaction?
theophylline is an eg of methylxanthine the action of this identified as a) release of ca from sarcoplasmic reticulum b) inhibition of phosphodiesterase c)blockade of adenosine receptor ESSENTIALS OF MEDICAL PHARMACOLOGY SEVENTH EDITION KD TRIPATHI PG NO.226
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Prodrug of cetrizine is
Ans. is 'c' i.e., Hydroxyzine Cetrizine is a metabolite of Hydroxyzine with marked affinity for peripheral HI receptors; penetrates brain poorly. It inhibits release of histamine and of cytotoxic mediators from platelets as well as eosinophil chemotaxis during secondary phase of allergic response. It is indicated in up...
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medmcqa_train
All the following are true of Craniopharyngioma except
Answer is C (Present in sella or infrasellar location): Some of these lesions arise from the sella, but most are suprasellar Q (Not infra-sellar). They arise from near the pituitary stalk and commonly extend into the supra sellar cistern. Craniopharyngiomas arise from Rathke's pouch and constitute 3-5% of all intracran...
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Characteristic feature of early congenital syphilis is:
D i.e. Vesicular rash with bulla over palms & soles
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All of the following are true of pulmonary embolism except:
Classic Findings in Pulmonary Embolism:- Right Hea strain and Acute Cor Pulmonale - sudden onset of pleuritic chest pain, hemoptysis and hypotension - Tall, peaked P waves in lead II (P pulmonale) - Right axis detion - Right bundle-branch block - S1Q3T3 pattern. On Xray :- Hampton's hump, Westermark sign (areas of rela...
155,781
medmcqa_train
A patient presented with pain in left eye associated with visual distrubance, also a history of blunt trauma to eye 4 month back, first investingation of choice is
A i.e. Intraocular tension This is a case of angle recession glaucoma
155,782
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Not seen in the peripheral smear in plasmodium falciparum infection -
Schuffner&;s dot in the Rbc can be seen in P. vivax and P. Ovale infection Maurer&;s dot -falciparum Ziemman&;s dot- malariae (refer pgno:61 baveja 3 rd edition)
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medmcqa_train
Carina is situated at which level
Carina is located at the bifurcation of trachea at lower border of T4.carina is the lower margin of lowest cailaginous ring that is a keel-shaped process curving downwards and backwards between the bronchi.The mucous membrane lining the area is highly sensitive and is origin of the protective cough reflex. It is visibl...
155,784
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Bromocriptine can be used in following conditions except
Refer KDT 7th/e Pg 239. Bromocripine is approved in diabetes mellitus not diabetes insipudus Bromocriptine is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
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Calcification of soft tissues without any distrubances of calcium metabolism is called
Ref,Robbins 9/e p65
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medmcqa_train
Wavelength of Nd:Yag laser
A i.e. 1040 nm
155,787
medmcqa_train
Least common organ affected in blast injury is -
Ans. is 'c' ie., Muscles * An explosion is a phenomenon resulting from sudden release of energy which is then dissipated by a blast wave, by translocation of objects, or by the generation of heat.* Injuries in explosion occur due to four factors:-1) Blast or shock wave# When an explosion occurs, the explosive material ...
155,788
medmcqa_train
A 58-year-old postmenopausal woman on estrogen replacement complains of recent onset of spotting. A bimanual pelvic examination is unremarkable. Most likely diagnosis?
Any postmenopausal woman who has been on unopposed estrogen and who is now experiencing vaginal bleeding is suspect for either endometrial hyperplasia or endometrial cancer. Endometrial hyperplasia is the end result of prolonged estrogenic stimulation of the endometrial mucosa. Morphologic forms of hyperplasia include ...
155,789
medmcqa_train
Methods of introducing gene in target cells are all except
Fluorescence in situ hybridization(FISH) is a cytogenetic technique that uses fluorescent probes that bind to only those pas of the chromosome with a high degree of sequence complementarity.
155,790
medmcqa_train
Treatment of pleomorphic adenoma without facial nerve infiltration and limited to superficial lobe:
Pleomorphic adenoma: * Most common salivary gland tumor * Benign, painless tumor with no facial nerve involvement * Most common site - Parotid, Submandibular, Sublingual, minor salivary gland * Location: Infront, below and behind ear lobule * Pathology: Mixed tumor has both epithelial and mesenchymal component * Tumor ...
155,791
medmcqa_train
Post is not required in all of the following conditions except:
Conditions where post should not be given: Any sign of endodontic failures are evident, i.e. tooth exhibits: Poor apical seal and poor quality obturation Active inflammation Presence of fistula or sinus Tender on percussion If adequate retention of core can be achieved by natural undercuts of crown. If there are h...
155,792
medmcqa_train
Pearson's Coefficient of skewness is defined as:
The coefficient used for checking the skewness of data, is called as the Karl Pearson coefficient, and is calculated as (Mean - Mode) S.D. Ref: Instant Medical Biostatistics, By Ranjan Das, Papri N. Das, 2009 Ane's Instant Medical Series, Page 41, 42.
155,793
medmcqa_train
Stocker's line is seen a –
Stocker's line is a line of iron deposition in the corneal epithelium seen adjacent to the head of the pterygium.
155,794
medmcqa_train
Ovarian artery is a branch of-
Ans. is 'a' i.e., Abdominal aorta * 'Ovarian artery is a branch of abdominal aorta'
155,795
medmcqa_train
Which of the following anti-angina drugs act by inhibition of long-chain 3-ketoacyl coenzyme A thiolase?
Trimetazidine Antianginal drug that act by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase enzyme. Reduced fatty acid metabolism and increased glucose metabolism in myocardium leading to a paial shift from FFA to glucose oxidation in the hea, which provides less ATP but requires less O2 and may there...
155,796
medmcqa_train
Post treatment HCG levels, during the follow up of molar pregnancy evacuation, comes back to normal in:
HCG follow up of vesicular mole: - weekly HCG estimation till negative (vesicular mole takes 9 weeks and paial mole takes 7 weeks) - weekly HCG till 3 more weeks - Once in a month for 6 months . Avoid pregnancy during this time. Use contraception, best being COCPs
155,797
medmcqa_train
which of the following antidepressent can be safely used in elderly depresion
NaSSA * IMPOANCE Nor adrenergic and specific serotonergic antidepressant * MECHANISM * Alpha 2 adrenergic receptor antagonism=== increase serotonin and NA * 5HT2,3 antagonist============increase sleep and appetite * DRUGS miazapine * USE Elderly with depression * SIDE EFFECTS hyperlipidemia Ref. kaplon and aock, synops...
155,798
medmcqa_train
Most common psychiatric disorder in community is
(A) Depression # DEPRESSION is the most common psychiatric illness in India.> Neurotic depression is far common than psychotic depression.> Neurotic depression is followed by anxiety neurosis is prevalence.> This is in contrast to West, where anxiety neurosis is the commonest.
155,799
medmcqa_train