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Patient because of positive biopsy findings and negative workup undergoes a radical prostatectomy. The pathology repo reveals Gleason score 9/10 and involvement of several pelvic lymph nodes. Which is the most likely site for prostatic cancer metastasis? | Bone metastasis is a characteristic feature of prostatic cancer. The lesions are typically osteoblastic on x-ray, and the serum acid phosphatase level becomes elevated | 7,200 | medmcqa_train |
Ahus reaction is what type of hypersensitivity reaction | Ahus reaction Localized area of tissue necrosis resulting from acute immune complex vasculitis, usually elicited in the skin. "SHARP" S- Serum sickness, Schick test, SLE H- HS pneumonitis (Farmers lung), HSP A- Ahus reaction R- Reactive ahritis, RA, Raji assay P - PAN, PSGN | 7,201 | medmcqa_train |
Investigation of choice for dysphagia for solids: | Answer is D (Manometry) Esophageal manometry is the gold standard test for esophageal motility disorders. Esophageal Motility Disorders : Manometry is the test of choice Achalasia Cardia Diffuse Oesophageal Spasm (Discoordinated motility) Nutcracker Oesophagus (Hypercontractile motility) Hypeensive LES (Hypercontractil... | 7,202 | medmcqa_train |
The following anticancer drug has high emetogenic potential | PLATINUM COORDINATION COMPLEXES Cisplatin Mech of action:- It is hydrolysed intracellularly to produce a highly reactive moiety which causes cross linking of DNA. The oured site is N7 of guanine residue. Adverse effects:- It is a highly emetic drug. Antiemetics are routinely administered before infusing it. The most im... | 7,203 | medmcqa_train |
Spironolactone should not be given with | Sprinolanctone is a potassium sparing diurectic It doesn't excrete potassium - increasing potassium levels in the blood ACE IN. also increases potassium levels in the blood Hence the combination is contraindicated Ref: KD Tripathi 8th ed | 7,204 | medmcqa_train |
A total of 5000 patients of glaucoma are identified and surveyed by patient interviews regarding family history of glaucoma. Such a study design is called- | Case series repo: A case series repo is a descriptive study where in more than one patients having a paicular disease are studied. No cause related analysis or hypothesis testing is involved. Case control study: Backward looking/ retrospective study in which multiple risk factors are studied together. Odd's ratio can b... | 7,205 | medmcqa_train |
Based upon this PA ulnar detion view of the wrist, what is the MOST likely diagnosis? | There is focal periostitis at the radial styloid. The radial styloid itself is normal. This is secondary to adjacent inflammation at the extensor pollicis brevis and abductor pollicis longus tendons (De Quervains tenosynovitis). The periosteal reaction of osteomyelitis is usually associated with abnormal underlying bon... | 7,206 | medmcqa_train |
Turbinate that aiculates with ethmoid is: | Middle turbinate and superior turbinate are a pa of the ethmoidal bone where as inferior turbinate is an independant bone which aiculates with the ethmoid bone,completing the medial wall of Nasolacrimal duct. Ref. Scotts Brown 7/e,Vol 2 p 1329. | 7,207 | medmcqa_train |
An enzyme that recognizes a specific (palindromic) sequence and cuts within a DNA molecule is? | ANSWER: (D) Restriction endonucleaseREF: Basic Genetics: Textbook and Activities by Ahmed Abouelmagd, Hussein M. Ageely page 117A palindromic sequence is a nucleic acid sequence {DNA or RNA) that is the same whether read 5' (five-prime) to 3' (three prime) on one strand or 5' to 3' on the complementary strand with whic... | 7,208 | medmcqa_train |
In pontaic fever, which antigen is seen in urine- | Ans. is 'a' i.e., Group specific antigen of Legionella serogroup-1 (LP1) o The examination of urine for legionella antigen by ELISA is a rapid and specific method for identifying L pneumophila,o However, disadvantage of urine antigen test is that it only detects Legionella pneumophila serogroup 1 (LP-1) and negative ur... | 7,209 | medmcqa_train |
A patient with Hypeension presents with Hypokalemia. Aldosterone levels and Renin levels are both elevated. The most likely diagnosis is | Answer- A. Renal Aery stenosisThe association of High aldosterone and High Renin levels in a hypeensive patient with hypokalemia suggests a diagnosis ofSecondary Hyperaldosteronism of from Renal Aery Stenosis. | 7,210 | medmcqa_train |
Mycosis fungoides: March 2013 | Ans. A i.e. Cutaneous T cell lymphoma Mycosis fungoides Mycosis fungoides is also known as: Cutaneous T cell lymphoma, Special features: - MC skin lymphoma, - Pautrier's microabscesses - Presents with diffuse erythroderma | 7,211 | medmcqa_train |
Me Callum patch is seen in the:(1988) | Ans: b | 7,212 | medmcqa_train |
The main catabolic product/products of purine nuleotides in humans is which one of the following: | Ans. (c) Uric AcidRef: Harper's Biochemistry, 30th edn. pg. 347-357Purines are metabolized by several enzymes:GUANINE* A nuclease frees the nucleotide* A nucleotidase creates guanosine* Purine nucleoside phosphorylase converts guanosine to guanine* Guanase converts guanine to xanthine* Xanthine oxidase (a form of xanth... | 7,213 | medmcqa_train |
Intraoperative Radiotherapy for treating pancreatic carcinoma mainly uses | Electron Beam is preferred for intraoperative Radiotherapy. The Intraoperative radiotherapy (IO) appears to be an ideal therapeutic strategy for pancreatic cancer, Having the advantage of enabling the delivery of high doses of radiation to areas that are at risk for microscopic disease, saving critical organs and reduc... | 7,214 | medmcqa_train |
Distally, Gubernaculum attaches to all except:- | Gubernaculum is the fibro muscular band which helps in descent of testes. Proximally, it is attached to:- Lower pole of testis. Peritoneum of saccus vaginalis in front of testis. Mesonephric duct. Distally, it is attached to:- Bottom of scrotum. Superficial perineal pouch. Pubic symphysis above penis. Saphenous opening... | 7,215 | medmcqa_train |
MMR (Measles, mumps, rubella) vaccine is an example of: | Ans: a. Live attenuated.. LIVE ATTENUATEDKILLED WHOLE ORGANISMTOXOID PROTEINSPOLYSACCHARIDEGLYCOCONJUGATERCOMBINANTBCG, Yellow fever, OPV, Measles, Mumps, Rubella,Typhoid, Varicella,Rotavirus, Cholera,Cold-adapted influenza,Rotavirus reassoants.ZostTyphoid, Cholera, Plague,Peussis, Influenza,Typhus, lPV, Rabies, JE,Tic... | 7,216 | medmcqa_train |
Which is the most common aerobic bacteria found in vagina? | Normal vaginal flora is mostly aerobic with an average of six different species of bacteria, most common of which is hydrogen peroxide producing lactobacilli. Other commonly found aerobic bacteria found in the vagina are Diphtheroids, Streptococci, Staphylococcus epidermidis and Gardenella vaginalis. Most prevalent ana... | 7,217 | medmcqa_train |
A 30 year old male presents with severe pain chest, breathlessness, hypotension and ECG shows ST elevation in V3, V4 V5 and V6 leads. He will be best treated with: | Percutaneous transluminal coronary angioplasty (PCTA or angioplasty) is a procedure that is commonly performed on people with hea disease. This procedure is done to open up the blood vessel to allow the blood to pass through more easily PTCA is a minimally invasive procedure to open up blocked coronary aeries, allowing... | 7,218 | medmcqa_train |
Which of the following-is the first sign of sexual maturity in boys? | Ans. (d) Increase in testicular sizePlease refer explanation of question 40 | 7,219 | medmcqa_train |
Thomsen friedensreich phenomenon is - | Ans. is 'b' i.e., Red cell agglutination by all blood group sera Thomsen-Freidenreich Phenomenono Red cell suspensions contaminated with certain bacteria, e.g. pseudomonas aeruginosa, become aggluiinable by alt blood group sera and even by normal human sera,o This is known as Thomsen Friedenreich phenomenon and is due ... | 7,220 | medmcqa_train |
In mood disorder, rapid cyclers are defined as | (A) 4 or more episodes per year# Rapid cycling:> Most people who meet criteria for bipolar disorder experience a number of episodes, on average 0.4 to 0.7 per year, lasting three to six months.> Rapid cycling, however, is a course specifier that may be applied to any of the above subtypes. It is defined as having four ... | 7,221 | medmcqa_train |
Best marker of SLE? | Ans. (b) Anti-ds DNA antibodies(Ref: Harrison 18th/chapter 319)Anti dsDNA is specific for SLE, only in high titers;But still, anti ds DNA is the best marker for SLE because its prevalence in SLE is 70%;Whereas, Anti Sm antibody, which is specific for SLE, but is seen in only 25% patients with SLE | 7,222 | medmcqa_train |
Enzyme deficiency in Hurler syndrome? | Disease name Abbretion Enzyme Defective GaG(s) affected Symptoms Hurler syndrome MPS I a-l-Iduronidase Dermatan sulfate, Heparan sulfate Mental retardation, coarse facial features, hepatosplenomegaly, cloudy cornea Reference: Harper; 30th edition; Page no:639; Table: 50-8 | 7,223 | medmcqa_train |
Which of the following is a prodrug ? | All ACE inhibitors are prodrugs except captopril and lisinopril. | 7,224 | medmcqa_train |
When the sympathetic nervous system is activated: | Ans. C. Norepinephrine is released from axons onto the arteriolar wallNerve fibers, not vascular smooth muscle, release norepinephrine. The norepinephrine from the sympathetic nerves simply diffuses from the axons and binds to specific receptors on smooth muscle cells. | 7,225 | medmcqa_train |
Histological finding in Reye&;s syndrome is | Reyes syndrome characterised by mitochondrial injury and decreased synthesis of mitochondrial enzymes in liver. Which leads to rise in blood ammonia and accumulation of triglycerides within hepatocytes. TEXTBOOK OF PATHOLOGY HARSH MOHAN 6TH EDITION PAGE 602 | 7,226 | medmcqa_train |
All of the following play a significant role in bone resorption except: | Pro-resorptive factors are hormones and cytokines are:-
PTH (Parathyroid hormone)
1,25dihydroxyvitamin D3,
IL-1
IL-6
TNF (Tumour necrosis factor)
LIF (Leukaemia inhibitory factor)
Corticosteroids, which activate osteoblasts and stroma cells to produce RANKL and depress OPG. | 7,227 | medmcqa_train |
Surgical treatment for asymptomatic uterine myoma is indicated if | Management of myomas: Asymptomatic : observation with regular follow up Size < 12 weeks Uncomplicated pregnancy with fibroid Surgery: Size > 12weeks Cornual fibroid causing infeility Pedunculated cornual fibroid Pregnancy with torsion of pedunculated fibroid Symptomatic myoma: Medical: Hormones to shrink the fibroid _ ... | 7,228 | medmcqa_train |
Tympanic membrane develops from? | Ans. (d) All three germ layersRef: Longman's medical embryology 12th ed. / 326 | 7,229 | medmcqa_train |
Mucoepidermoid carcinoma arises form | Mucoepidermoid carcinomas are composed of variable mixtures of squamous cells, mucus-secreting cells, and intermediate cells. "The low-grade mucoepidermoid carcinoma is composed of largely mucin-secreting cells, whereas in high-grade tumors, the epidermoid cells predominate." They are the most common malignant tumors o... | 7,230 | medmcqa_train |
Parasites causing lung infestation are - | The worm lie in the lung parenchyma and are surrounded by a fibrous capsule formed by host tissue.Inflammatory reaction to the worms and their eggs lead to granuloma formation,cystic dilatation of bronchi,abscesses and pneumonitis.Patient present with cough,chest pain and haemoptysis (refer pgno:131 baveja 3 rd edition... | 7,231 | medmcqa_train |
Culex mosquito is a vector for: | ANOPHELES CULEX AEDES MANSONIA Boat shaped Small in clusters Single ; Cigar shaped Star shaped ; in clusters Rest parallel to water surface Rest at an angle to water surface Rest at an angle to water surface Attached to roots of Aquatic plants - Sits by making an angle of 45o with surface - Have straight body & spotted... | 7,232 | medmcqa_train |
True statement about diphtheria toxin is | Toxigenicity of the diphtheria bacilli depends on the presence in it of corynephages which acts as the genetic determinant controlling toxin production. The diphtheria toxin acts by inhibiting protein synthesis. Specifically, a fragment B heparin binding and fragment A inhibits polypeptide chain elongation in the prese... | 7,233 | medmcqa_train |
All except one are formulas used to calculate fluid replacement in burns patient | Holiday segar formula is not used to calculate fluid replacement in burns patient. | 7,234 | medmcqa_train |
Drug of choice for multidrug resistant staphylococcus aureus is: | Ans: c (Vancomycin)Ref: Harrison 16 ed pg. 821, KDT 6 ed. Pg.732Vancomycin is the drug of choice for MRS A. Quinupristin and dalfopristin are both streptogramin antibiotics that act on MRSA and VRSA. They are used mainly for VRSA.Drugs useful against MRSA:Vancomycin Cotrimoxazole Doxycycline Minocycline Fluroquinolones... | 7,235 | medmcqa_train |
A 26 year old female patient complains of discoloration with her upper front teeth. Intra-oral examination reveals intrinsic staining with maxillary incisors. Dentist prepares the tooth to receive veneers. This type of margin design is called as: | The blending effect is predominantly related to smaller restorations, surrounded by hard dental tissues, such as composite restorations. It can reduce suboptimal shade matches due to operational error or lack of satisfactory match in the shade guide or restorative material. The veneers designed with “contact lens effec... | 7,236 | medmcqa_train |
A 2 year old born out of consanguineous marriage, had a history of the collodion membrane. He had large, thick, plate-like brown scaling generalized distribution; no erythroderma and ectropion. Which disease is it? | Ans. B. Lamellar ichthyosisLamellar ichthyosis (LI)* Collodion baby at birth as the baby is covered by a thickened collodion-like membrane which is then shed* Scaling occurs over the whole body, including creases and bends* The scale in LI is typically large, dark brown or grey and firmly adherent* Drooping of lower ey... | 7,237 | medmcqa_train |
Carey coombs murmur, which is false - | A sho, mid-diastolic murmur is rarely heard during an episode of acute rheumatic fever (Carey-Coombs murmur) and probably is due to flow through an edematous mitral valve. An opening snap is not present in the acute phase, and the murmur dissipates with resolution of the acute attack. Complete hea block with dyssynchro... | 7,238 | medmcqa_train |
Tolvaptan is approved for use in- | Tolvaptan is a vasopressor receptor antagonist used to correct hyponatremia in the treatment of syndrome of inappropriate water excretion or SIADH :-
Syndrome of inappropriate secretion of ADH is caused due to excesive secretion of antiduretic hormone.
Antidiuertic hormone (ADH) or arginine vasopressin is synthesized b... | 7,239 | medmcqa_train |
Organ most vulnerable to ischaemic due to shock? | Ans. is 'd' i.e., Hea o The susceptibility of a tissue to hypoxia influences the likelihood of infarction. o Neurons are most sensitive to hypoxia (irreversible changes develop in 3-4 minutes) followed by myocardial cells (irrversible changes develop in 20-40 minutes). o Fibroblasts are amongst the most resistent cells... | 7,240 | medmcqa_train |
After premature delivery, mother's milk is low in | Ans. a (Lactose) (Ref OP Ghai 6th/ p. 158; 7th/p. 131, 134)After premature delivery, mother's milk is low in:# Calcium # Phosphates # LactoseADVANTAGES OF BREAST MILK# Docosahexanoic acid (DHA, W3, 2:3) present in breast milk helps in brain development.# Maximum synthesis of breast milk occurs at 12 months.# Has better... | 7,241 | medmcqa_train |
Alkaline douch solution of nose does not contain: | Ans. D Nasal irrigation and removal of crusts - warm normal saline or an alkaline solution made by Soda bicarbonate 1 pa Sodium biborate 1 pa Sodium chloride 2 pas in 280 ml of water Initially irrigation are done 2 or 3 times a day but later every 2 or 3 days is sufficient 25 % glucose in glycerine - nose is painted th... | 7,242 | medmcqa_train |
Shoest acting anticholinesterase is - | Ans. is 'a' i.e., Edrophonium o Edrophonium is the shoest acting anti-ChE. o Why is it so, lets see : o When carbamates (other than edrophonium) and organophophates react with cholinesterase, they form covalent bond at esteratic site, which is considerably resistant to hydrolysis. o In contrast, edrophonium binds elect... | 7,243 | medmcqa_train |
Injury to the nerve originating from C5 in Brachial plexus leads to | The question speaks of Dorsal scapular nerve on whose damage leads to winging of scapula. | 7,244 | medmcqa_train |
Which of the following features is not included in psychosis | A i.e. Panic attack - Hypochondrial symptoms are commonly present in major depression. Panic attacksQ (generalized anxiety disorder) is a neurotic disorder Delusion & hallucinations are common in psychosis (MDP, Schizophrenia & delusional disorder). | 7,245 | medmcqa_train |
True about composition of hospital waste | - the average composition of hospital wastes in India is; - 15% - 10% metals- 1% infectious wastes-1.5% -4% wastes-53.5% Reference : Park&;s textbook of preventive and social medicine, 23rd edition, pg no:790, table 2. <\p> | 7,246 | medmcqa_train |
Spring catarrah is - | It is considered a hypersensitivity reaction to some exogenous allergen, such as grass pollens. VKC is thought to be an atopic allergic disorder in many cases, in which IgE-mediated mechanisms play an impoant role. Such patients may give personal or family history of other atopic diseases such as hay fever, asthma, or ... | 7,247 | medmcqa_train |
Most common histological type of thyroid carcinoma is | (B) Papillary type # Morphological variants of thyroid carcinoma and their approximate frequencies are: Papillary carcinoma 75-85% Follicular carcinoma 10-20% Medullary carcinoma 5% Anaplastic carcinoma < 5%> Histology type Incidence Papillary 80% Follicular 10% Medullary 5% Anaplastic 1 %> Papillary carcinoma thyroid:... | 7,248 | medmcqa_train |
Which vitamin deficiency may be observed in a patient on INH therapy: September 2012 | Ans: B i.e. Pyridoxine The main cause of pyridoxine deficiency is a lack of pyridoxine in the diet. Another cause of vitamin B6 deficiency is the use of the ATT medication isoniazid, and for this reason, it is usually replaced with vitamin B6 whilst using this drug. | 7,249 | medmcqa_train |
Hypersegmented neutrophils are seen in - | Ans. is 'c' i.e.. Megaloblastic anemia Findings of megaloblastic anemiaPeripheral bloodo Macrocytosis i.e., megaloblastic RBC - Due to nuclear1 cytoplasmic asynchrony,o Macrocytes lack central pallor of normal RBC.o Anisopoikilocytosis - Marked variation in shape and size,o Majority of RBCs appear as macroovalcytes.o F... | 7,250 | medmcqa_train |
A 20-year-old male presented with high-grade fever, groin pain and a swollen scrotum for 1 week and are worsening progressively. On examination, Tender inguinal lymphadenopathy Scrotal swelling with hydrocoele Lymphatic streaking Blood samples are taken and a parasite infection is suspected. Which of the following is t... | This is a case of filariasis (acute lymphadenitis) due to Wuchereria bancrofti. Microfilariae are found in blood, hydrocoele and other body fluids. 1 Wuchereria bancrofti Sheath, no nuclei in the tip of the tail 2 Brugia malayi Sheath, 2 distinct nuclei in the tip of the tail 3 Loa loa Sheath, nuclei extending to the t... | 7,251 | medmcqa_train |
All causes brain lesions except | giardiasis is caused by Giardia lamblia. the parasite attaches itself to the epithelial surface of duodenum and jejunum and causes disturbance of intestinal function leading to malabsorption of fat. Patient presented with loose stool and mild steatorrhoea. .Baveja textbook of parasitology 3rd edition. | 7,252 | medmcqa_train |
All of the following metabolic pathways occur in both Cytoplasm and Mitochondria, except: | Ans. (a) GlycolysisRef.: Harpers Biochemistry 30th edti. /142-144* Glycolysis occurs in cytoplasm.* There are two major sites for gluconeogenesis, the liver and the kidneys.* The liver accounts for 90% of gluconeogenesis in the body and the remaining 10% occur in the kidney and other tissues of the body.* The liver and... | 7,253 | medmcqa_train |
Shailza, a 40-year-old female is having headache for the past 6 months. All her investigations were normal. She had several consultations and she had no relief of her symptoms. She still believes that she has some problem in her brain. Likely diagnosis could be: September 2010 | Ans. D: Hypochondriasis Hypochondriasis, hypochondria refers to excessive preoccupation or worry about having a serious illness. An individual suffering from hypochondriasis is known as a hypochondriac. Often, hypochondria persists even after a physician has evaluated a person and reassured them that their concerns abo... | 7,254 | medmcqa_train |
Not a feature of acute aerial Occlusion ? | Ans is 'a' ie Cyanosis | 7,255 | medmcqa_train |
Bajaj committee in 1986 proposed? | <p> Manpower and planning. Reference:India health repo 2010,page no;132. <\p> | 7,256 | medmcqa_train |
Instrument of choice for diagnosing pediatric retinal disorders | Retcam has been used to diagnose pediatric retinal disorders. It has a probe which is put over eye which captures the fundus photo. It can also do fluorescein angiography and is used for tele consultation too High Yield Facts *Factors responsible for ROP : Low GA is more impoant than LBW *WHO Vision 2020 program target... | 7,257 | medmcqa_train |
Brunner's glands are seen in - | The presence of mucous duodenal (Brunner’s) glands in the submucosa is indicative of upper duodenum. These submucosal glands are absent in the jejunum, ileum and the entire large intestine. | 7,258 | medmcqa_train |
All are seen in injury to common peroneal nerve except? | A i.e. Loss of sensation ove soleSole is supplied by medial & lateral plantar and sural branches of tibial nerveQ anteriorly (from medial to lateral) and calcaneal branches of tibial nerveQ posteriorly (i.e. over heel). So it is not affected in common peroneal nerve injury. | 7,259 | medmcqa_train |
Haemoglobin can bind to all the following except | Ans: c (SO2) Ref.Ganong 22nd ed/p.667.Hb does not bind to SO2.Functions of Hb:-It facilitates 02 transportIt facilitates C02 transportIt has an important role as a bufferIt transports NO.Hemoglobin binds NO in the lungs and releases it in the tissues, where it promotes vasodilation.In arterial blood,Total volume of C02... | 7,260 | medmcqa_train |
Cadaveric spasm -a) Immediate after deathb) After 2 hours of deathc) Affects voluntary musclesd) Affects involuntary muscle | Cadaveric spasm occurs immediately after death and affects voluntary muscles. | 7,261 | medmcqa_train |
The treatment of acute myocardial infarction includes which of the following- | Ref : harrisons-manual-of-medicine-16th-edition pg no: 622-623 TREATMENT Initial Therapy Initial goals are to: (1) quickly identify if patient is candidate for reperfusion therapy, (2) relieve pain, and (3) prevent/treat arrhythmias and mechanical complications. * Aspirin should be administered immediately (162-325 mg ... | 7,262 | medmcqa_train |
An 8 year old boy presented with fever and bilateral cervical lymphadenopathy with prior history of sore throat. There was no hepatomegaly. The peripheral blood smear shows > 20% lympho-plasmacytoid cells. The most likely diagnosis is - | Ans. is 'b' i.e., Infectious Mononucleosis Infectious mononucleosis Infectious mononucleosis : Is the most characteristic disease produced by Epstein Barr Virus Clinical features : o Most infections are asymptomatic. o Headache, Abdominal pain, chills also seen in few casees. o Fever, malaise, sore throat, (exudative p... | 7,263 | medmcqa_train |
In surgical anterolateral approach to tibia, incision is taken over the tibialis anterior muscle mass rather than over the shaft. What is/ are the advantages? | Ans. is 'd' i.e., All the above * In surgical anterolateral approach to tibia, incision is taken over the tibialis anterior muscle mass rather than over the shaft. Following are the advantages :i) If required can be converted to an extensile approach. Entire tibia from knee to ankle can be exposed.ii) Open wound treatm... | 7,264 | medmcqa_train |
A young patient had a history of fall. The physician placed his hand on the patient's chin and instruct him to rotate his head to the opposite side against resistance. But he was unable to perform the action. Which of the nerve is injured in this patient? | The sternocleidomastoid muscle creates the borders for both the anterior and the posterior triangles of the neck, and is innervated by the spinal accessory nerve (CN XI). To test the sternocleidomastoid muscle, the physician will place her hand on the patient's chin and instruct him to rotate his head to the opposite s... | 7,265 | medmcqa_train |
Most common cause of death in measles is | . | 7,266 | medmcqa_train |
IQ in mild mental retardation is | Ans. is 'a' i.e., 50-70 | 7,267 | medmcqa_train |
Reticulocytosis is NOT a feature of: | Answer is D (Anemia of chronic Renal Failure) Anemias of chronic renal failure and chronic disease are associated with low or normal reticulocyte counts. Elevated reticulocyle count is a feature of hyperproliferative anemias including PNH, hereditary spherocytosis and anemia after blood loss. | 7,268 | medmcqa_train |
Feline esophagus is seen in: | - Feline esophagus is seen in both Eosinophilic Esophagitis>GERD. It is characteristic of Eosinophilic esophagitis so it serves as a better answer. - Eosinophilic Esophagitis: A barium swallow should be the first test obtained in the patient with dysphagia EE has a characterised finding often called the "Ringed esophag... | 7,269 | medmcqa_train |
Lady with infeility with bilateral tubal block at cornua : best method of management is : | IVF | 7,270 | medmcqa_train |
Local anesthetic action is a result of blockade of the movement of wof channels | LOCAL ANAESTHETICS MECHANISM OF ACTION The LAs block nerve conduction by decreasing the entry of Na+ ions during upstroke of action potential (AP). As the concentration of the LA is increased, the rate of rise of AP and maximum depolarization decreases causing slowing of conduction. Finally, local depolarization fails ... | 7,271 | medmcqa_train |
Odd pair - | Ans. is 'd' i.e., Erythema chronicum migrans - malignancyo "Erythema gvratum repens" is a rare and characteristic rash strongly associated with malignancy .It consists of wavy erythematous concentric bands that can be figurate, gyrate or annular.These bands are arranged in parallel rings and lined by a fine trailing ed... | 7,272 | medmcqa_train |
All of the following are true about rituximab except? | Ans. d. Dose independent pharmacokinetics (Ref: Harrison 19/e p2147,18/e p2749; Katzung 12/e p646; htt[://www.isdbweb. org/documents/file/1442_2pdf)Pharmacokinetics of rituximab (monoclonal antibodies) is dose dependent.'The rate of uptake and elimination of antibodies by target-mediated pathways is a function of dose ... | 7,273 | medmcqa_train |
NOT a constituent of embalming fluid: AIIMS 08 | Ans. Ethanol | 7,274 | medmcqa_train |
Which of the following is true of mumps ? | Ans. is 'c' i.e., Meningoencephalitis can precede parotitis "Aseptic meningitis may develop before, during, after or in the absence of parotitis." About other options o Mainly parotid glands are involved, but sublingual and submaxillary glands may also be involved. o Patient is infectious 4-6 days before the onset of s... | 7,275 | medmcqa_train |
Which of the following is not a characteristic finding in Henoch Schonlein Purpura? | Henoch Schonlein Purpura is a small vessel vasculitis characterized by palpable purpura, ahralgia, gastrointestinal signs and symptoms and glomerulonephritis. Patients have a normal platelet count, other laboratory findings includes mild leukocytosis, occasional eosinophilia, normal serum complement and elevated IgA. R... | 7,276 | medmcqa_train |
False statement about selegeline is - | Ans. is 'a' i.e., It is a MAO-A inhibitor o Selegeline (deprenyl) inhibitis MAO-B o Unlike nonselective MAO inhibitors, selegiline in low doses does not interfere with peripheral metabolism of dietary amine (tyramine), accumulation and hypeensive reaction (cheese reaction) does not develop, while intracerebral degradat... | 7,277 | medmcqa_train |
Most common cause of ARDS in children is: | c. Severe pneumonia with sepsis(Ref: Neonatal and Pediatric Respiratory Care 4/e By Brian K. Walsh p 564)Pneumonia, sepsis and aspiration are the most common cause of ARDS and ALI in children | 7,278 | medmcqa_train |
The most frequently implicated antibiotic among the causes of drug induced liver injury is: | Amoxicillin-clavulanic acid : The most frequently implicated antibiotic among cases of drug-induced liver injury. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2560 | 7,279 | medmcqa_train |
Which of the following is a nonmodifiable risk factor for coronary hea disease? | park's textbook of preventive and social medicine 23rd edition. *non modifiable risk factors for CHD :age,sex,ethnicity, genetic factors. *modifiable risk factors: obesity,alcohol,physical activity, saturated fat, socio-economic status. | 7,280 | medmcqa_train |
Families which lags behind rest of community, is known as | Problem Family: Is a family which lags behind rest of the community; underlying factors in most problem families are those of personality, relationships, backwardness, povey, illness, mental and social instability, character defects and marital disharmony. Standards of life are generally far below the accepted minimum ... | 7,281 | medmcqa_train |
The serum concentration in which of the following human IgG subclasses is maximum? | IgG 1 - 65%, IgG2- 23%. IgG3 -8% IgG4 - 4% | 7,282 | medmcqa_train |
29 year old female with history of Sjogren's syndrome presents with a 2 day episode of watery diarrhea 2 days ago. Physical examination is unremarkable. Because of her history, the physician decides to check her urine electrolytes. Urine chemistry: K = 31, Na = 100, Cl = 105. Her current diagnosis is? | * The urine electrolytes are used to distinguish between A and diarrhea * UAG is an indirect measure of ammonium excretion * UAG = (Na + K) - Cl * UAG = ( 100 + 31 ) - 105 = 26 * A positive UAG suggest A because in the setting of diarrhea, ammonium chloride concentration in the urine would be high and the UAG would be ... | 7,283 | medmcqa_train |
Prolonged latent phase is seen in : | In primi, the latent phase is often long (about 8 hours) during which effacement occurs; the cervical dilatation averaging only 0.35 cm/hr. In multi, the latent phase is sho (about 4 hours) and effacement and dilatation occur simultaneously. Latent phase is the preparatory phase of the uterus and the cervix before the ... | 7,284 | medmcqa_train |
A 60-year-old female is having proximal muscle weakness with increased serum creatinine kinase. The probable diagnosis is: | A. It is a subacute inflammatory myopathy affecting adults, without rash, involvement of eye, family history of neuromuscular disease B. Dermatomyositis is identified by a rash preceding muscle weakness. C. Inclusion body myositis has an asymmetrical muscle involvement. D. Limb girdle muscular dystrophy and would have ... | 7,285 | medmcqa_train |
You are in the causlity when a student, Kumar is brought in with a shoulder injury sustained while playing football. In comparing the symmetry of his two shoulders, you notice a marked elevation of the distal end of his clavicle with respect to the acromion on the injured side. X-ray exam reveals a grade III shoulder s... | A shoulder separation is an injury to the acromioclavicular joint. A first degree separation involves stretching the ligaments, but maintenance of the joint. A second degree separation involves tearing of the joint capsule and coracoclavicular ligament, but still continuity. A third degree separation involves total dis... | 7,286 | medmcqa_train |
Hemolytic Uremic Syndrome is characterized by -a) Microangiopathic haemolytic anaemiab) ↓ed LDHc) Thrombocytopeniad) Renal failuree) Positive Coomb's test | Hemolytic uremic syndrome
Hemolytic uremic syndrome is characterized by the triad of :
Anemia (microangiopathic hemolytic anemia).
Renal failure (microangiopathy of kidney involving glomerular capillaries and arterioles).
Thrombocytopenia (due to platelet consumption).
Hemolytic uremic syndrome is most common is c... | 7,287 | medmcqa_train |
All of the following antihistaminic agents lack anticholinergic property EXCEPT : | All the drugs listed in the question are second generation anti-histaminic agents except promethazine. | 7,288 | medmcqa_train |
Totipotency of embryonic stem cell is due to that they? | Ans. is 'a' i.e., Can differentiate into all the tissues of embryonic or extraembryonic cell types Stem cells base on their potency* Potency refers to ability of stem cells to differentiate into specialized (mature) cell type:-A. Totipotent stem cells - These cells are produced from fertilization of sperm and ovum and ... | 7,289 | medmcqa_train |
Copper -- T is preferably inseed postnatal after : | 8 weeks | 7,290 | medmcqa_train |
Pneumothorax of what size generally needs operative treatment? | Small pneumothoraxes (<20%) that are stable may be monitored if the patient has few symptoms Moderate (20%-40%) and large (>40%) pneumothoraxes nearly always are associated with persistent symptoms that cause physical limitations and require intervention. | 7,291 | medmcqa_train |
Most Common extranodal site of Lymphoma in 14W is? | Ans. is 'a' i.e., CNS | 7,292 | medmcqa_train |
Which one of the following stains is specific for Amyloid? | Ans. is 'c' i.e., Congo Red "To differentiate amyloid from other hyaline deposits (eg. Collagen andfibrin), a variety of histochemical techniques are used, of which the most widely used is Congo Red " - Robbins 7th/e p. 259Staining for Amyloido Congo red : It is the most widely used specific stain for amyloid.o Iodine ... | 7,293 | medmcqa_train |
Physiological uncoupler is ? | Ans. is 'd' i.e., All of the above | 7,294 | medmcqa_train |
Type II hypersensitivity - | autoimmune haemolytic anaemia, transfusion reactions,idiopathic thrombocytopenic purpura,graves disease,myasthenia gravis are the examples of type 2 hypersensitivity.Harshmohan textbook of pathology 7th edition | 7,295 | medmcqa_train |
Gas gangrene is caused by: March 2012 | Ans: A i.e. Clostridium welchii Conditions and pathogens Established pathogens (clostridium) for gas gangrene (group) includes Cl. Perfringens/ welchii, Cl. septicum & Cl. Novyi Established pathogen (clostridium) for tetnaus include Cl. Tetani Established pathogens (clostridium) for food poisoning (group) includes Cl. ... | 7,296 | medmcqa_train |
The main enzyme responsible for activation of xenobiotics is - | Most important reaction in biotransformation of xenobiotics is oxidation reaction. The most important enzyme for oxidation reactions is cytochrome P450. | 7,297 | medmcqa_train |
ABC transpoer ? | Ans. is'a' i.e., P. glycoproteinATP-binding cassette transpoers (ABCtranspoers) are integral transmembrane proteins that utilize ATP as an energy source to translocate a variety of substrates across membranes.P-glycoprotein is an ATP-binding cassette (ABC) transpoer and is an impoant factor to limit membrane permeabili... | 7,298 | medmcqa_train |
Site where endolymph is seen: | (b) Scala media(Ref. Scott Brown, 8th ed., Vol 2, page 545)Endolymph is present in the membranous labyrinth, whereas perilymph is present in the bony labyrinth.Hence scala vestibuli, scala tympani and their interconnection helicotrema, which are parts of bony labyrinth, are filled with perilymph.Scala media, utricle, s... | 7,299 | medmcqa_train |
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