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Monitoring Progression of Scleroderma


Project Description

This is a website for visualising datasets to study protein expression in Scleroderma patients. The website is able to generate the following plots:

  • Correlation Plot
  • Boxplot
  • UMAP plot
  • Volcano plot
  • Violin plot

Table of Contents


Introduction

Scleroderma is an autoimmune disease that can cause thickened areas of skin and connective tissues. To gain a deeper understanding of this condition, analysing the expression of different proteins observed in Scleroderma patients is highly beneficial. This website utilizes a dataset to generate 4 graphs, enabling researchers to analyse results while requiring minimal bioinformatics expertise.


Features

Selecting Protein

Users can search for proteins using multiple naming conventions including:

  • Protein Name
  • Full Protein Name
  • Entrez Gene ID
  • Entrez Gene Symbol

Alternatively, users can utilize the volcano plot on the main page to select a protein by hovering over and clicking on the plot.

Volcano Plot

Correlation Plot

Box Plot

UMAP Plot

Violin Plot


Installation

  1. Clone the repository:
 git clone https://github.com/ainiimura21/name1.git
  1. Install dependencies:
pip install numpy pandas matplotlib seaborn streamlit scanpy

Usage

To run the project, use the following command:

streamlit run app/main.py

Contributing

  1. Fork the repository.
  2. Create a new branch: git checkout -b feature-name.
  3. Make changes.
  4. Push your branch: git push origin feature-name.
  5. Create a pull request.