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Instruct: Identify the main category of Biorxiv papers based on the titles Query: DNA supercoiling-mediated collective behavior of co-transcribing RNA polymerases
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes Potentially pre-malignant lesions (PPOLs) are composed of keratinocyte...
cell biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Modeling microRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
genomics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Synaptotagmin-7 enhances phasic dopamine release Dopamine released from substantia nigra pars compacta (SNc) neurons modulates movement, motivation, and reward. In addition to their tonic firing pattern, dopamine neurons al...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Effects of long-lasting insecticide net (LLINs) ownership/utilisation indicators on annual household malaria episodes (AHMEs) in three Health Districts in Cameroon
epidemiology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues Desminopathies comprise hereditary myopathies and cardiomyopathies caused by mutations in the intermediate filament...
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Zebrafish caudal fin amputation induces a metabolic switch necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Direct cochlear recordings show human hearing nerve activity is modulated by selective attention The architecture of the efferent auditory system enables prioritization of strongly overlapping spatiotemporal cochlear activa...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Robust Characterization of Non-Invasive Post-Traumatic Osteoarthritis Mouse Model
animal behavior and cognition
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Electric shock causes fear-like persistent behavioral response in the nematode Caenorhabditis elegans Behavioral persistency reflects internal brain states, which are the foundations of multiple brain functions. However, ex...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: The evolution of widespread recombination suppression on the Dwarf Hamster (Phodopus) X chromosome
genomics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Rap-Phr systems in B. subtilis 3610 affect matrix gene expression and play a role in biofilm formation in vitro and on the plant root Natural isolates of the soil-dwelling bacterium Bacillus subtilis form robust biofilms un...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Parent-Child Autonomic Synchrony During Vicarious Extinction Learning in Pediatric PTSD
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: A Web Portal and Workbench for Biological Dissection of Single Cell COVID-19 Host Responses Numerous studies have provided single-cell transcriptome profiles of host responses to SARS-CoV-2 infection. Critically lacking how...
immunology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Development of methods for purification of individual biological active substances obtained from extracts of Hedysarum neglectum
plant biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: A multivariate view of cognitive performance reveals positive correlation in the Trinidadian Guppy (Poecilia reticulata) Cognitive variation is common among-individuals and can be consistent across time and context. From an...
animal behavior and cognition
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota
systems biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: SARS-CoV-2 B.1.617.2 Delta variant emergence and vaccine breakthrough The SARS-CoV-2 B.1.617.2 (Delta) variant was first identified in the state of Maharashtra in late 2020 and spread throughout India, outcompeting pre-exis...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A Multisite and Multimodal Comparative Study of Cerebellar Connectome Between Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative The Receptor Binding Domain (RBD) of SARS-CoV-2 is the primary target of neutralizing antibodies. We ...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A Massively Parallel Trafficking Assay Accurately Predicts Loss of Channel Function in KCNH2 Variants
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Synapses learn to utilize pre-synaptic noise for the prediction of postsynaptic dynamics Synapses in the brain are highly noisy, which leads to a large trial-by-trial variability. Given how costly synapses are in terms of e...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Non-coding RNAs Associated with Prader-Willi Syndrome Regulate Transcription of Neurodevelopmental Genes in Human Induced Pluripotent Stem Cells
molecular biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome A loss of the checkpoint kinase ATM leads to impairments in the DNA damage r...
molecular biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Effects of diversifying the planting period of maize on herbivorous and their natural enemies
ecology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Detecting intragenic trans-splicing events with hybrid transcriptome sequencing in cancer cells Trans-splicing can generate non-co-linear (NCL) transcripts that consist of exons in an order topologically inconsistent with t...
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A digitization theory of the Weber-Fechner law
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: HALO: A software tool for real-time head alignment in the MR scanner Magnetic resonance imaging (MRI) studies in human subjects often require multiple scanning sessions/visits. Changes in a subjects head position across ses...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: scGRNom: a computational pipeline of integrative multi-omics analyses for predicting cell-type disease genes and regulatory networks
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: The role of migration in mutant evolution in fragmented populations Mutant evolution in fragmented populations has been studied extensively in evolutionary biology. With an increased focus on evolutionary dynamics in medica...
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Machine learning prediction of antiviral-HPV protein interactions for anti-HPV pharmacotherapy
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif Eliciting antibodies to surface-exposed viral glycoproteins can lead to protective responses that ultimately control and prevent...
immunology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Guided Axon Outgrowth of Neurons by Real-Time Femtosecond Laser Penetration on a 4 μm Thick Thin-Glass Sheet
bioengineering
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Plasmids as donors of Insertion Sequence elements mediating colistin resistance in Klebsiella pneumoniae Colistin is a last resort antibiotic for the treatment of carbapenemase producing Klebsiella pneumoniae (CRKP). In lin...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types: chronicles of the MEMENTO challenge.
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance Streptococcus pyogenes is a globally prominent human-specific pathogen responsibl...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Impact of maternal protein restriction on hypoxia-inducible factor (HIF) expression in male fetal kidney development
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization Sequencing of cell-free DNA (cfDNA) is currently being used to detect cancer by searching both for mutational and non-m...
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Mitonuclear interactions produce extreme differences in response to redox stress
biochemistry
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: A cell type-specific multiomics uncovers a guard cell-specific RAF15-SnRK2.6/OST1 kinase cascade Multicellular organisms such as plants contain different cell types with specialized functions. Analyzing the characteristics ...
plant biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Down Regulation Of IL-1β Secretion By TGF-β1 In Macrophages Infected With Dengue Virus
immunology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Function-structure Coupling:White matter fMRI hyper-activation associates with structural integrity reductions in schizophrenia BackgroundWhite matter (WM) microstructure deficit may be an underlying factor in the brain dys...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A Herpes Simplex Virus Type-1-derived influenza vaccine induces balanced adaptive immune responses and protects mice from lethal influenza virus challenge.
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Paf1C denoises transcription and growth patterns to achieve organ shape reproducibility In multicellular systems, all cells exhibit transcriptional noise. However, its exact contribution to morphogenesis often remains uncle...
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking CLU+ CAF expression with HSF1 signaling Cancer-associated fibroblasts (CAFs) give rise to desmoplastic stroma, which supports tumor pro...
cancer biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Vision-related convergent gene losses reveal SERPINE3's unknown role in the eye
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Distinct REV-ERBα Conformational State Predicted by GaMD Simulations Leads to the Structure-Based Discovery of Novel REV-ERBα Antagonist REV-ERB is a nuclear hormone receptor that plays important role in the regulation of m...
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Tom70-based transcriptional regulation of mitochondrial biogenesis and aging
cell biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae Species of the mustelid subfamily Guloninae inhabit diverse habitats on multiple continents, and occupy a variety of ecol...
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Topography-dependent gene expression and function of common cell archetypes in large and small porcine airways
genomics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Discovery of SARS-CoV-2 Mpro Peptide Inhibitors from Modelling Substrate and Ligand Binding The main protease (Mpro) of SARS-CoV-2 is central to its viral lifecycle and is a promising drug target, but little is known concer...
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Temporal response characterization across individual multiomics profiles of prediabetic and diabetic subjects
genomics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory Hippocampal somatostatin (SOM) cells are dendrite-projecting inhibitory interneurons. CA1 SOM ...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Phase tracking algorithms detect both real and imaginary components of outer hair cell nonlinear membrane capacitance that exhibits dielectric loss.
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Drug-dependent morphological transitions in spherical and worm-like polymeric micelles define stability and pharmacological performance of micellar drugs Significant advances in physicochemical properties of polymeric micel...
pharmacology and toxicology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Dynamic reconfiguration of macaque brain networks during free-viewing of natural scenes
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Scarcity of hosts for gregarious parasitoids indicates an increase of individual offspring fertility by reducing their own fertility The gregarious parasitoid strategy allows multiple larvae to complete development in a sin...
zoology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
cancer biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Penalized Logistic Regression Analysis for Genetic Association Studies of Binary Phenotypes IntroductionIncreasingly, logistic regression methods for genetic association studies of binary phenotypes must be able to accommod...
genetics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Cortico-Subcortical Interactions in Overlapping Communities of Edge Functional Connectivity
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: ABCA1 causes an asymmetric cholesterol distribution to regulate intracellular cholesterol homeostasis Cholesterol is a major and essential component of the mammalian cell plasma membrane (PM) and the loss of cholesterol hom...
cell biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Arf6 is necessary for high level Wingless signalling during Drosophila wing development
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Retinal input influences pace of neurogenesis but not cell-type configuration of the visual forebrain The brain is assembled during development by both innate and experience-dependent mechanisms1-7, but the relative contrib...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: MorphoGraphX 2.0: Providing context for biological image analysis with positional information
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Neural Networks for self-adjusting Mutation Rate Estimation when the Recombination Rate is unknown Estimating the mutation rate, or equivalently effective population size, is a common task in population genetics. If recombi...
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A curated collection of human vaccination response signatures
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: A DNA-based optical force sensor for live-cell applications Mechanical forces are relevant for many biological processes, from wound healing or tumour formation to cell migration and differentiation. Cytoskeletal actin is l...
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Direct precise measurement of the stall torque of the flagellar motor in E. coli
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: A Spatiotemporal Reconstruction of the C. elegans Pharyngeal Cuticle Reveals a Structure Rich in Phase-Separating Proteins Roughly 4.5 million species of ecdysozoan animals repeatedly shed their old cuticle and construct a ...
systems biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Optical activation of TrkB neurotrophin receptor in mouse ventral hippocampus promotes plasticity and facilitates fear extinction
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Disruption of nucleoid expanded conformation by toxic aberrant proteins synthesized in Escherichia coli Aminoglycoside antibiotics interfere with selection of cognate tRNAs during translation, resulting in the production of...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Distinguishing between recent balancing selection and incomplete sweep using deep neural networks
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Emergent population activity in metric-free and metric networks of neurons with stochastic spontaneous spikes and dynamic synapses We show that networks of excitatory neurons with stochastic spontaneous spiking activity and...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: DJ-1 glyoxalase activity makes a modest contribution to cellular defense against methylglyoxal damage in neurons
biochemistry
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: In amygdala we trust: different contributions of the basolateral and central amygdala in learning whom to trust Human societies are built on cooperation and mutual trust, but not everybody is trustworthy. Research on rodent...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A possible way to relate the effects of SARS-CoV-2 induced changes in transferrin to severe COVID-19 associated diseases
biophysics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Optimal strategies to protect a sub-population at risk due to an established epidemic Epidemics can particularly threaten certain sub-populations. For example, for SARS-CoV-2, the elderly are often preferentially protected....
ecology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: A marine fungus efficiently degrades polyethylene
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Vendor-neutral sequences (VENUS) and fully transparent workflows improve inter-vendor reproducibility of quantitative MRI PurposeWe developed an end-to-end workflow that starts with a vendor-neutral acquisition and tested t...
bioengineering
Instruct: Identify the main category of Biorxiv papers based on the titles Query: In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Oct1 recruits the histone lysine demethylase Utx to promote lineage specification The pathways used by cells to transition between undifferentiated, pluripotent state and tissue-specific states are incompletely understood. ...
developmental biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Evolution of a costly immunity to cestode parasites is a pyrrhic victory
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice As SARS-CoV-2 continues to cause morbidity and mortality around the world, there is an urg...
immunology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability
cell biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Artificial mimicry of seasonal transcriptome dynamics in Arabidopsis thaliana reveals short- and long-term responses to environmental conditions O_LIPlants must respond to various environmental factors that change seasonall...
plant biology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: scINSIGHT for interpreting single-cell gene expression from biologically heterogeneous data
bioinformatics
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Basal amygdala inputs to the medial prefrontal cortex mediate fear memory strengthening Survival critically depends on the memorization of stimuli recurrently predicting pleasant or aversive experiences. Memory strengthenin...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Single-cell RNA sequencing identifies phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow
cell biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Costs dictate strategic investment in dominance interactions Dominance is important for access to resources. As dominance interactions are costly, individuals should be strategic in who they interact with. One hypothesis is...
animal behavior and cognition
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Single-cell immune profiling reveals the impact of antiretroviral therapy on HIV-1-induced immune dysfunction, T cell clonal expansion, and HIV-1 persistence in vivo
immunology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Synchronic resisto-genesis effects identify most prevalent mechanism in Acinetobacter baumannii Acinetobacter baumannii as deadliest infection agent to ICU patients challenge experimental treatment in lack of new antibiotic...
microbiology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Simulation-based inference of evolutionary parameters from adaptation dynamics using neural networks
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Expectations boost the reconstruction of auditory features from electrophysiological responses to noisy speech Online speech processing imposes significant computational demands on the listening brain, the underlying mechan...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Acute myeloid leukemia cells are targeted by the naturally occurring CXCR4 antagonist EPI-X4
cancer biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Prediction of broad chemical toxicities using induced pluripotent stem cells and gene networks by transfer learning from embryonic stem cell data The assessment of toxic chemicals using animals has limited applicability to ...
pharmacology and toxicology
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Real Time Face Recognition with limited training data: Feature Transfer Learning integrating CNN and Sparse Approximation
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Loss of SORCS2 is associated with neuronal DNA double-strand breaks SORCS2 is one of five proteins that constitute the Vps10p-domain receptor family. Members of this family play important roles in cellular processes linked ...
neuroscience
Instruct: Identify the main category of Biorxiv papers based on the titles Query: Parallel evolution of urban-rural clines
evolutionary biology
Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts Query: Nanoscopical analysis reveals an orderly arrangement of the presynaptic scaffold protein Bassoon at the Golgi-apparatus 1.Bassoon is a large, 440 kDa, scaffold protein of the specialized sites mediating neurotransmitter rel...
neuroscience