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Ans. is 'a' i.e., Saluretic effect is greater than thiazide
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It is a monoclonal antibody produced by injecting HER-2 antigen; 'cl' i.e., The protein HER2/NEU is expressed in increased amount by breast cancer cells Cancer cells express ceain antigen on their surface. These antigens can be made the target of chemotherapies. Specific antibodies have been developed against these cel...
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Cutaneous larva currens / racing larva, is a feature of strongyloides stercoralis.
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Ans. is 'a' i.e., EnolaseINHIBITORS OF GLYCOLYSIS AND CITRIC ACID CYCLEGLYCOLYSISGlyceraldehyde 3 phosphate dehydrogenaseIodoacetateEnolaseFluridePhosphogJycerate kinaseArsenatePYRUVATE - ACETYL CoAPyruvate DehydrogenaseArseniteCITRIC ACID CYCLEAconitaseFluroacetatea Ketoglutarate dehydrogenaseArseniteSuccinate dehydro...
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Diffuse radiolucent areas with ill-defined borders may be apparent radiographically on the mesial or distal aspects of teeth in the cervical regions between the edge of the enamel cap and the crest of the alveolar ridge (The gap between the CEJ and the alveolar bone crest contains dentin only). This phenomenon, called ...
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Ans. Coical bridging veins
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Ans. (b) sternocleidomastoid muscleRef: Dhingra's ENT 6th ed/ 78* Mastoid tip is in relation to two muscles:# Sternocleidomastoid muscle# Digastric muscle (posterior belly)* If there is abscess from:# SCM muscle: Bezolds abscess# Digastric area: Citelli s abscess.Also KnowDifferent MASTOID ABSCESSESAbscessLocationWild'...
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Ans. is 'b' Pilosebaceous Gland Acne vulgaris is due to obstruction of Pilosebaceous Duct Lesions consists of - Comedone*PapulesPustulesCystsAlso knowAcne has equal sex incidence *Most common site - Face*
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Answer is A (Spastic paralysis): Spinal Shock is associated with Flaccid paralysis and not Spastic paralysis Spinal shock Flaccid Paralysis (complete motor paralysis) Areflexia Sensory loss (anesthesia to all modalities) Bladder Involvement (usually areflexic bladder with urinary retention)
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40 weeks
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Picornaviruses genera of veterinary impoance are aphthovirus, which causes foot and mouth disease cattle, and cardiovirus of mice, including encephalomyocarditis REF:ANANTHANARYANAN TEXTBOOK OF MICROBIOLOGY 9EDITION PGNO.484
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Earliest nerve involved by acoustic neuroma - Vth nerve / trigeminal nerve. Earliest manifestation of Vth nerve involvement is decreased corneal sensitivity leading to loss of corneal reflex.
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Acute asthma and Emphysema- TLC | due to air trapping Myasthenia gravis- TLC | RV| Obstructive Restrictive | in airflow | Lung volume - Expiratory -Inspiratory COPD Asthma Bronchiectasis ILD Scoliosis NM causes FEV1-| FVC- Normal or | TLC - Normal or | | PEFR Normal | | |PEFR Management of COPD Group A Low Risk, low sy...
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Adenovirus in gene therapy: ds DNA virus Replication deficient Used in In Vivo approach gene therapy As vaccines, For cancer therapy Advantages: Remain as an episome (extrachromosomal DNA) So doesn't integrate into the genome. (no chance of inseional mutagenesis) The maximum size of the inse by the adenoviral vector is...
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B i.e. Closed reduction & internal fixation Principles, Rationale and Treatment Plane Of Intracapsular Fracture Neck Femur Femoral head should not be sacrificed lightly in every fracture, paicularly when the fracture is undisplaced or can be reduced accurately. Primary prosthetic replacement should be reserved for the ...
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Normally Eustachian tube (ET) is closed and opens intermittently during yawning, swallowing and sneezing through active contraction of Tensor vili palatini muscle.
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The ovarian aeries are branches of the abdominal aoa and originate below the renal aeries Ref: Gray's anatomy 40th edition, Chapter 102.
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This is an image of the distal esophagus from a barium swallow demonstrating an irregular, somewhat nodular filling defect probably due to carcinoma oesophagus
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Fabry's disease is an X-linked dominant disorder. Angiokeratoma corporis diffusum is another name for it. Neuropathy usually stas in the childhood. It is overshadowed by complications arising from the associated premature atherosclerosis that lead to death by the fifth decade of life. ALSO KNOW: Fabry's disease is caus...
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C i.e. Sodium Valproate Rapid Cycling MDP - The patient must have at least 4 episodes within 12 months of mood disturbance (that meet criteria of major depressive, manic, hypomanic or mixed episode). - It is usually due to use of conventional antidepressant especially tricyclic & presence of hypothyroidism. So antidepr...
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Ans. is 'c' i.e., Biopsy * An autopsy (also known as a post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a highly specialized surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause and manner of death and to evaluate any disease or injury that m...
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Answer is B (Homocysteine) There is a strong positive correlation between atherosclerosis and circulating levels of Homocysteine'' Hyperhomocysteinemia has been most consistently linked with atherosclerosis and coronary thrombotic events "Patient with clinical and angiographic evidence of coronary aery disease tend to ...
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Reinke's oedema - diffuse symmetrical swelling of both vocal cords Reinke's oedema is caused by vocal abuse or smoking. There is diffuse symmetrical swelling of both vocal cords. Vocal cord stripping is the treatment of choice. Enough mucosa should be preserved for epithelialization. Ref : Diseases of ENT by Dhingra 6t...
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A ns. is 'c' i.e., Emulsification of lipids o Emulsification is the process which breaks down ingested fats (mainly triglycerides) into smaller droplets so that they can be digested more efficiently. Thus emulsification mainly helps in digestion of ingested fats.o Micelles formation is the process in which digested fat...
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Ans. C. Paragonimus with 2 layersa. Paragonimus westermani is the major species of lung fluke to infects humans, causing paragonimiasis,b. The species sometimes is called the Japanese Lung fluke or Oriental Lung fluke.c. Unembryonated eggs are passed in the sputum of a human or feline. Two weeks later, miracidia develo...
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Ans. is 'd' i.e., 30 Community health centreo Each community' health centre covers a population of80000 to 1.20 Lakh.o It has 30 beds and specialist in Surgery', Medicine, Obstetrics & Gynaecology, and pediatrics with x-ray and laboratory facilities.o For strengthening preventive and promotive aspects of health care, n...
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Ans. a.-0.5x180degSimple myopic astigmatism is one in which one meridian is emmetropic and other meridian is myopic.Hence needs correction only in one meridian with concave (-ve) cylinders. So the answer is -0.5x180deg.ASTIGMATISM TYPES AND CORRECTIONTypes of astigmatismDescriptionOpticsCorrectionSimple myopic astigmat...
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Hepatitis B virus natural infection induces lifelong immunity. The immunity is primarily mediated by humoral antibodies against HBsAg. Antibodies to HBsAg are protective.  These antibodies bind to surface antigens or with the virus and prevent it from interacting with receptors on the hepatocytes. These antibodies appe...
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Best site to measure core body temperature after death is Rectum. But in cases of sodomy temperature is measured from Inferior surface of liver. Other suitable sites are external auditory canal, nasal passages or by inseing a thermometer into the peritoneal cavity by a small opening.
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Ans. is 'a' i.e., Nodular type of cholangiocarcinoma o Klatskin tumour is an extrahepatic type of cholangiocarcinoma.o According to their localization, cholongiocarcinomas are classified intoIntrahepatic (10-20 %)Extrahepatic (80-90%)o The extrahepaticforms include perihilar tumors known as Klastkin tumors, which are l...
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Ref. Gray’s anatomy.  41st edition. Page.  982 All of the spinal nerves contain both sensory and motor functions and can be organized on the basis of the functional components of each nerve. General Somatic Afferent (GSA) fibers are related to receptors for pain temperture and mechanical receptors in the skin, muscles...
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Vitamin D is a group of fat-soluble secosteroids responsible for enhancing intestinal absorption of calcium and phosphate. Calcitriol circulates as a hormone in the blood, regulating the concentration of calcium and phosphate in the bloodstream and promoting the healthy growth and remodeling of boneRef: Ganong&;s revie...
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Necrosis Necrosis is not generally seen in sympathetic ophthalmia. Lymphocytes, giant cells, and eosinophils are seen within the choroid. Some have stated that eosinophils may be seen in early disease, before granulomatous inflammation is present, although this is not, diagnostic.
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The buttocks are the preferred site for administration of the intramuscular injection.  The muscles (gluteal) of this area are thick and are utilized frequently in daily activities, thus causing complete absorption of drugs.  To give the injection at the proper site, the gluteal region can be divided into four quadrant...
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Ans. b (Goniotomy). (Ref. Parson, Diseases of Eye, 18th/pg.214)BUPHTHALMOSNormal IOT in Schiotz tonometer is 14-20 mmHg.Glaucoma Index =Initial IOP-----------Facility of outflow(Normal < 100)Treatment of choice for buphthalmos is goniotomy.Eventual success rate with goniotomy is 85%.However in resistant cases trabecule...
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Ans. b (Gamma ray) (Ref. H - 16th/pg. 1294)IONIZING RADIATIONS# Alpha (a) radiation- Consists of heavy, positively charged particles containing two protons and two neutrons.- Alpha particles are usually emitted from isotopes with an atomic number of >82, such as uranium or plutonium.- Due to their large size, alpha par...
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Cryotherapy T/T of anogenital was Topical medication Trichloracetic acid or Podophyllin resin applied weekly. hniquinod or podofilox should also be used. Crvotherapy and laser therapy Cryotherapy (freezing) using nitrous oxide or carbon dioxide is used in was who do not respond to topical treatment. Carbon dioxide lase...
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Answer is 'a' i.e. Spinal cord injury Causes of Paralytic ileus Postoperative - a degree of ileus usually occurs after any abdominal procedure and is self-limiting, with a variable duration of 24-72 hrs. Post op ileus may be prolonged in the presence of hypoproteinemia or metabolic abnromality. Paralytic ileus is a sta...
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Topical steroids are not recommended in post surgery for antrochoonol polyps. For antrochoanal polyps, cause is infection and not the allergy. Antrochoanal polyps are single, unilateral and rarely recur. Topical steroids are rarely recommended.
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Ans. is 'a' i.e., Thalidomide * Has been explained in previous sessions
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Cozen's test - In this test active extension of wrist against resistance produces pain at the point of common extensor origin. It is considered a positive finding for lateral epicondylitis or Tennis elbow.
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Paranoid PD These individuals are sensitive and suspicious. They mistrust others and suspect their motives and are prone to jealousy. They are touchy, irritable, argumentative, and stubborn Some of these people have a strong sense of self-impoance and special ability
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Ans. is 'd' i.e., Choline o Acetylcholine is synthesized in the cytosol of nerve terminal from acetyl-CoA and choline, in the presence of choline-O-acetyltransferase.Acetyl CoA + Cholinecholine-O-acetyltransferase---------------------Acetylcholine + CoA
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Ans. D Ach* Awake state: Increase activity of norepinephrine- and serotonin-containing neurons (locus coeruleus and raphe nuclei) and reduced level of activity in acetylcholine- containing neurons (pontine reticular formation). Reduced GABA release and increase histamine release is also there.* REM state: Decrease acti...
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Aneurysms are congenital or acquired dilations of blood vessels or the hea . "True" aneurysms involve all three layers of the aery (intima, media, and adventitia) or the attenuated wall of the hea; these include atherosclerotic and congenital vascular aneurysms, as well as ventricular aneurysms resulting from transmura...
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Ans. is 'd' i.e., Inferior mesenteric aeryBlood supply of Gil' A. Celiac trunk - Foregut (stomach to where the bile duct enters the duodenum).Left gastric aerySplenic aeryLeft gastroepiploic aerySho gastric aeryHepatic aeryRight gastric aeryRight and left hepatic aeryGastro-duodenal aery - right gastroepiploicSuperior ...
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Shot gun These are single or double barrelled smooth bored weapons in which pellets are used as projectile. Shot guns may be muzzle loading or breech loading. It may be of single barrel or double barrel. In double barrel, the lower barrel is used for loading caridges. Ref: FORENSIC MEDICINE AND TOXICOLOGY DR PC IGNATIU...
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Continuous dribbling of urine following hysterectomy points towards urinary fistulas as the diagnosis. In case of urinary fistulas, if the patient never needs to void as there is continuous dribbling it signifies that the fistula communicates with the bladder. If, there is filling and emptying of bladder along with the...
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In SIADH, ADH increases so more activation of V2 receptor, so more water absorption. The patients suffer from dilutional hyponatremia. Option B: Managed by Desmopressin / Nasal spray Option C: Managed by Cryoprecipitate / VW Factor Option D: No definitive treatment, patient dies more often
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Opening  of  K+ channel >> Closing of Na channel  The  main  factor  is  opening of K+ channel.  Although  Ganong has  maintained  both closure  of  Na+ channels  and  opening of one  type  of  K+ channel and closure of Na channel only, The recent concept is K+ channel opening is the main reason of phase 1.  Phase  0 ...
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Catalse neutralizes residual H2O2 that interfers with composite bonding and polymerization.
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Adduction of thumb. Injury to the Ulnar nerve Ulnar nerve is most commonly injured at the elbow, where it lies behind the medial epicondyle and at the wrist where it lies in front of flexor retinaculum. In high ulnar nerve injury at or proximal to elbow, all the muscles supplied by the ulnar nerve in the forearm and ha...
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Ans. is 'b i.e., 5-7 years o The growth of lymphoid tissue is most notable during mid-childhood. o Children between 4 and 8 years of age often have hyperophied tonsils and large lymph nodes, which is infact a sign of lymphoid hyperplasia.
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*In a bilateral congenital dislocation of hip the gait is described as 'duck like waddle. In unilateral cases the child lurches towards affected side. This is known as abductor lurch or Trendelenburg gait. REF:Ref: Tachdijian's pediatric Ohopaedics 3rd/e p.83
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Ans. A i.e. Oxalic acid The vomit in oxalic acid poisoning has a coffee ground appearance because the oxalic acid badly corrodes the stomach walls. There may be bloody vomiting for the same reason.
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Staphyloma refers to a localised bulging of weak and thin outer tunic of the eyeball (cornea or sclera), lined by uveal tissue which shines through the thinned out fibrous coat. Types of staphyloma - Anterior staphyloma Intercalary staphyloma Ciliary staphyloma Equatorial staphyloma Posterior staphyloma Ref;A.K.Khurana...
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Weber syndrome is a lesion of the anterior midbrain at the level of superior colliculus involves: Oculomotor nerve Ipsilateral downward & laterally deted eye Substantia nigra Contralateral parkinsonism Coicobulbar fibers Coicospinal tract
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Circumferences of the head in different attitudes: -- Complete flexion Biparietal-suboccipito-bregmatic. Shape -- almost round 27.5 cm (11") -- Deflexed Biparietal-occipito-frontal. Shape -- oval 34 cm (13 1/2 ") -- Incomplete extension Biparietal-mento-veical. Shape -- bigger oval 37.5 cm (15") -- Complete extension B...
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In shoulder separation, either or both the acromioclavicular and coracoclavicular ligaments can be partially or completely torn through. The acromioclavicular joint can be interrupted and the distal end of the clavicle may deviate upward in a complete separation, while the upper limb droops away inferiorly, causing a "...
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Ans. First 10 days of menstrual cycle
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Ans. is 'c' i.e., Ringer lactate Fluid resuscitation in burn injury Parkland formulaa a. Initial 24 hours: Ringer's lactated (RL) solution 4 ml/kg/% burn for adults and 3 ml/kg/% burn for children. RL solution is added for maintenance for children: 4 ml/kg/hour for children weighing 0-10 kg 40 ml/hour +2 ml/hour for ch...
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Corrosives - mechanism of action - Corrosive poison erodes the surface in contact by extracting water from local tissue, coagulation of protein, conve hemoglobin to hematin.
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Salmonella belongs to CDC category B.
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Capecitabine and 5 - Flurouracil can cause Hand-Foot syndrome characterized by pain, redness and swelling over palms & soles.
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Ans. is 'a' i.e., Falciparum Malaria o It is mainly used for multidrug resistant falciparum malaria.
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Cavitation and pleural effusions are comon complications of Staphylococcal pneumonia D/D OF CAVITARY LESIONS IN LUNG C - carcinoma (metastasis, squamous cell Ca, lymphomas) A - autoimmune (Wegener's Granulamatosis, rheumatoid nodules) V - vascular (emboli) I - infection (staph pneumonia, lung abscess, fungal pneumonia,...
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NK cells are considered as an innate immune defence against cells that have lost the expression of ClassI MHC like virus infected cells and malignant cells. Reff: Ananthanarayanan & Panikers textbook of microbiology 9th edition pg: 137
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Ans is d None o Breast feeding should be initiated within 30 min. of a normal vaginal delivery. o Breast feeding should be initiated within 4 hrs of delivery by caesarian section.
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Ans. All
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DNA microarray is used to identify thousands of different gene expressions at the same time- Recommended for unexplained intellectual disability. Fluorescent in situ hybridisation/Chromosomal painting- uses fluorescent probes for specific chromosome Multiplex Ligation-dependent probe Amplification- uses specific marker...
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The child in the question is having a capillary hemangioma on the face and is suffering from seizures. Both of these are characteristically seen in Sturge weber syndrome. Clinical features: Unilateral, cutaneous capillary angioma involving the upper face, leptomeningeal angiomatosis and choroidal angioma Focal or gener...
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The net effect of insulin on lipid metabolism is to reduce the release of fatty acids from the stored fat.Among the tissues, adipose tissue is the most sensitive to the action of the insulinLipogenesisIt is the process by which acetyl-CoA is conveed to fats.The former is an intermediate stage in metabolism of simple su...
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Exercise causes hyperkalemia because Na+-K+ pump cannot keep pace with the K+ efflux from muscle during the depolarization-repolarization process of the sarcolemmal membrane during muscle contraction. Causes of shift of K+ out of cells i.e. Hyperkalemia: Insulin deficiency Beta adrenergic antagonist Acidosis Hyperosmol...
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A. i.e. Macule
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(a) Towards the opposite side(Ref. Cummings, 6th ed., page 2510)In bi-thermal caloric test the normal response is C O W S, i.e. with Cold water nystagmus is towards the Opposite side and with Warm water it is towards the Same side.If both meatus are irrigated simultaneously with cold water the normal response is an up-...
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Thyroid disease may affect the heart muscle directly or there may be excessive sympathetic stimulation. Common symptoms of thyrotoxic heart disease include palpitations, exertional dyspnea, and worsening angina. Atrial fibrillation is particularly common in older individuals.
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Its tempting here to go for Hypothyroidism but that is usually associated with weight gain. However, pituitary tumors and craniopharyngiomas can cause increase in PRL and consequent galactorrhea , weight loss attributed then to the malignant process. Ref - Harrison 20e pg2673
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Answer is C (Metabolic acidosis):
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Ans. is 'c' i.e., 5000
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Waste water from community containing solid and liquid excreta Sewage is defined as waste water from community containing solid and liquid excreta. "Sullage" is waste water from the community which does not contain human excreta e.g., waste water from kitchens and bathrooms.
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Ans. (d) Haptoglobin increased(Ref: Robbins 9th/pg 631-632)HaptoglobinA glycoprotein that is synthesized in the liver.It consists of two pairs of a chains and two pairs of b chains.With hemolysis, free Hb readily dissociates into dimers of a & b chains; the a chains bind avidly with the b chains of haptoglobin in plasm...
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Ans is 'c' i.e. 10 Feature Score Eye opening to pain 2 Inappropriate words 3 Localizes pain 5 Total 10
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Dihydroaemisinin * It has potent schizontocidal action.* These drugs are lethal to early malarial gametes but not mature ones.* They do not kill vivax hypnozoites* The duration of action is sho and recrudescence rate is high.* Dose adjustment is not required in hepatic or renal failure.* Oral bioavailability is around ...
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The iliopubic tract fan out with fascia laterally. The iliopubic tract is a thickening of the transversalis fascia lying immediately posterior to the inguinal (poupa's ) ligament. It goes from the anteior superior iliac spine (ASIS) superolaterally and arches across the front of the femoral sheath. Attachments : Medial...
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The enzymes routinely measured in the clinical laboratory for the purpose of diagnosing and monitoring myocardial infarction include creatine kinase (CK), aspaate aminotransferase (sGOT or AST), and lactate dehydrogenase (LDH).
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Red degeneration This complication occurs during pregnancy (2nd trimester) Myoma becomes tense and tender Symptoms: Abdominal pain, constitutional upset and fever Rx :bed rest and analgesics. Never operate In case of torsion of fibroid, severe abdominal pain is there but fever and raised leucocyte count is not seen. Fi...
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Ans. is 'a' i.e., Mature dendritic cells . Mature B cells and T-cells before antigenic exposure are called naive B and T cells respectively. Sequence of events in activation of naive T cells : . Immature dendritic cells in the epidermis are called langerhans cells. . These immature dendritic cells ( langerhans cells) c...
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Ans. is 'b' i.e., DNA+Histones o Nucleosomes are primary structural units of chromatin.o It consists of DNA bound to protein histonesQ, i.e. core of protein histones wrapped with DNAQ.o Histones are basic proteins rich in lysine and argininine2.o These positively charged amino acids interact with negatively charged pho...
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Ans. is 'a' i.e., Ebola, 'b' i.e. Yersinia, 'c' i.e. C. botulinum Bioterrorism . A bioterrorism attack is the delibrate release of viruses, bacteria or other germs ( agents) used to cause illness or death in people, animals or plants. These agents are typically found in nature, but it is possible that they could be cha...
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Echinococcus multilocularis: It causes the rare but the most serious condition of alveolar / multilocular hydatid disease in humans. The adult worm is smaller than E. granulosus and lives in the intestines of foxes, dogs and cats. Human infection develops from eating fruits / vegetables contaminated with their faeces. ...
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Epithelial tumors are classified into Ameloblastoma and adamantinoma, though both the tumors show same type of histopathology, they are not interchangeable. Ameloblastoma Adamantinoma Site Mandible Tibia Most common site for Ameloblastoma is mandible Most common type of cancer of mandible is squamous cell carcinoma.
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For a variety of reasons, lipid—mainly as triacylglycerol—can accumulate in the liver. Extensive accumulation is regarded as a pathologic condition. Nonalcoholic fatty liver disease (NAFLD) is the most  common liver disorder worldwide.  NAFLD is considered by many to be the hepatic manifestation of the ‘metabolic syndr...
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Cells have developed many mechanisms to remove free radicals and thereby minimize injury. Free radicals are inherently unstable and decay spontaneously. There are also nonenzymatic and enzymatic systems that contribute to inactivation of free radicals . * The rate of decay of superoxide is significantly increased by th...
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Meningioma is the most common extra - Axial intracranial tumor. Most common intra - Axial intracranial tumor is Glioma.
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Ans is option 3- CDNA of pancreatic cell. Ref Harrison 19 /2402,2411
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Theophylline is used in bronchial asthma. Its mechanism of action is: Inhibition of phosphodiesterases particularly PDE-4. Antagonism of adenosine receptors. Enhancement of histone deacetylation. Acetylation of histone is required for activation of inflammatory gene tran­scription. By inhibiting this process, low-dose...
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When an extract of abrus seeds is injected under the skin, symptoms resemble viperine snakebite and as such poisoning is not suspected. There is inflammation, edema, oozing of hemorrhagic fluid from the site of puncture and necrosis may occur. Commonly used as cattle poison in Indian villages to get the hide or for tak...
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Epiphyseal dysgenesis means fragmented/punctate epiphysis. Epiphyseal dysgenesis is characteristic of hypothyroidism.
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C i.e. Follows ischemia of forearm
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Ans. is 'd' i.e., Howell-Jolly bodies Chronic Manifestations of splenectomv include : Marked variation in size and shape of erythrocytes - anisocytosis / poikilocytes Howell - Jolly bodies : nuclear remnants Heinz bodies : denatured haemoglobing Basophillic stippling Occasional nucleated erythrocyte in peripheral blood
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