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Cadaveric spasm, also known as postmoemspasm, instantaneous rigor, cataleptic rigidity, or instantaneous rigidity, is a rare form of muscular stiffening that occurs at the moment of death and persists into the period of rigor mois. In cadeveric spasm, only a pa of muscles are involved and it causes stiffening of that p...
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Ans: A (Strychnine poisoning) Ref: The Essentials of Forensic Medicine and Toxicology by KS Narayan Reddy. 29th edition. 2010. Pg:Explanation:Refer 2011 Forensic medicine question explanation
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Ans. is 'b' i.e., Dermatomyositis o Dermatomyositis is a connective-tissue disease related to polymyositis that is characterized by inflammation of the muscles and the skin. o It is a systemic disorder that may also affect the joints, the esophagus, the lungs, and, less commonly, the hea. o On the muscle biopsy, there ...
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Increased trabecular meshwork outflow is the mechanism of action of new drug Rhopressa (rho- kinase inhibitors) New Drugs in Glaucoma Anecorvate - Angiostatic steroid. Ethacrynic acid latrunculins - cellular cytoskeletal modulators. Alter TM shape. Olmesean, lomerizine, nivaldipine - improves vascular perfusion. Neurot...
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Volkmann's contracture is a flexion deformity of the fingers and sometimes the wrist from an ischemic necrosis of the forearm flexor muscles. Bennett's fracture is a fracture at the base of the metacarpal of the thumb. Scaphoid fracture occurs after a fall on an outstretched hand and involves the scaphoid and lunate bo...
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C. jeikeium-causes bacteremia with high moality rates in immunodeficient. C. urealyticum-causes UTI. Both are lipophilic.
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Microphakia, spherophakia (microspherophakia) all are types of abnormal lens.Microphakia - Abnormal smallness of the lens of the eye.Spherophakia (microspherophakia) - in spherophakia the lens is small and spherical (increase the anterior and posterior curvature of the lens). Angle-closure glaucoma occurs when the smal...
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Ans. is d i.e. Menorrhagia I know many of you might be thinking - Inversion of uterus is the correct option. It is correct that. Inversion of uterus occurs in a fundal submucous fibroid polyp when it is being extruded. But chronic inversion of the uterus as such is a rare entity. Most common symptom of fundal fibroid l...
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The anterior layer of the rectus sheath below the arcuate line is formed by aponeuroses of the external and internal oblique and transverse abdominal muscles, but there is no posterior layer of the rectus sheath below the arcuate line. The anterior layer of the rectus sheath above the umbilicus is formed by aponeuroses...
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The second branchial arch forms bony and muscular structures from the ear (proximally) to the hyoid bone (distally), including the muscles of facial expression that are innervated by the facial nerve (cranial nerve (CN) VII). The posterior belly of digastric muscle develops from the mesoderm of second branchial arch he...
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Ans. is 'c' i.e., Gastroduodenal aeryGastroduodenal aery gives following branches :-Right gastroepiploic aerySuperior pancreaticoduodenal aery
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Ans. is 'a' i.e., Yolk sac o In early fetal life (upto 10 weeks) erythropoiesis occurs in yolk sac.o By third month of intrauterine life erythropoiesis moves to liver (major) and spleen which are the chief site for erythropoiesis until 5 months of fetal life.o After that erythropoiesis occurs in bone marrow.o In childr...
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Answer is C (Factor V Leiden Mutation) Factor V Leiden mutation is the most common inherited thrombotic disorder Most common genetic cause for thrombophilia Factor V Leiden Most common congenital cause of venous thrombosis Factor V Leiden Most common hereditary blood coagulation disorder Factor V leiden
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Ans. is 'b' i.e., Retinal Vitamin A (Retinol)The retinoids are a family of molecules that are related to retinol (Vitamin A) and are essential for :VisionReproductionGrowthMaintenance of epithelial tissues Structure of vitamin AVitamin A is often used as a collective term for several related biologically active molecul...
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D i.e. Lying to standing change in posture When a person moves from a supine position to standing position volume of blood pools in the lower extremity because of high compliance of veins & venous return decreases. As a result of decreased venous return the length of ventricular cardiac muscle fibres is decreasedQ and ...
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Advantages of Ether Ether is cardiovascular stable agent. maintains hypoxic and hypercapnic drive good analgesic good muscle relaxation bronchodilator cheap disadvantage slow induction /slow recovery Irritant nature of ether increases salivary and bronchial secretions highly inflammable
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Ans. is 'c' i.e., Interstitial nephritisCauses of eosinophiluriao Acute allergic interstitionl nephritis o Schistosomiasiso Rapidly progressive glomerulonephritis o Chronic pyelonephritiso Acute glomerulonphritis o Graft rejection acute phaseIg A nephropathy, Henoch - Schonlein purpura o Athroembolic renal diseaseProst...
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Smack is synthetic opioid Ref : Krishnan vij Textbook of Forensic medicine and Toxicology 5th edtion ; pg no - 492
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Atropine is an anticholinergic drug. Its toxicity causes: Dry mouth (and not excessive salivation) Hot skin Dilated pupil and photophobia Excitement Flushing of skin Hypotension → cardiovascular collapse Convulsions and coma
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The quadrate lobe is an area of the liver situated on the under the surface of the right lobe, bounded in front by the anterior margin of the liver; behind by the poa hepatis; on the right, by the fossa for the gall-bladder; and on the left, by the fossa for the umbilical vein.
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Drugs used for LA induced seizure :- Benzodiazepines (midazolam), Barbiturates (thiopentone), Propofol.
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Adverse effects ofTCAs l. Anticholinergic - Dry mouth, bad taste, urinary retention, blurred vision, palpitation, constiPation. 2. Sedation, mental confusion, weakness. 3. Increased appetite and veigfit gain. 4. Sweating andfinc tremer. 5. Decreased seizure threshold (clomipramine, maprotiline & bupropion). 6. Postural...
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Ref - Harrison's internal medicine 20e p2517
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Monitoring is the performance and analysis of routine measurements aimed at detecting changes in the environment or health status of population.
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Gustafson's ranking of structural changes in age determination A = Attrition A-0 No Attrition A-1 Attrition lying within enamel A-2 Attrition reaching the dentin A-3 Attrition reaching the pulp P = Periodontosis P-0 No Periodontosis P-1 Periodontosis just begun P-2 Periodontosis along first 1/3rd of root P-3 Periodonto...
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Behcet's syndrome
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Ans. (b) Placenta previaRef.: D.C. Dutta 8th ed. / 290, Williams 22nd ed./822-823* MacAfee and Johnson Regimen is a Conservative Management in Placenta Previa: This consists of complete bed rest, tocolysis, and close observation of patient.* Steroids are generally given to enhance lung maturity.* To undertake this regi...
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Hoarseness is due to deposition of myxomatous tissue in the vocal cords. Nasal stuffiness is due to predominance of parasympathetic activity. Hypothyroidism also causes Meniere's like syndrome.
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Chin cap was introduced by Oppenheim. It delivers a force of 800 - 1200 (400 - 600 gms/side). The patient is asked to wear the appliance for 12-14 hours/ day.
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The clinical presentation of primary hyperparathyroidism is described on page 769. Parathyroid bone disease is now rare due to earlier diagnosis and treatment. Osteitis fibrosa results from increased bone resorption by osteoclasts with fibrous replacement in the lacunae. This may present as bone pain and tenderness, fr...
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Serial Interval - Interval between primary case and secondary case. Incubation Period- Entry of organism till first sign / Symptom. Generation time - Interval between entry of organism till maximum infectivity of that person or case.
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It is important to know that, confabulation is also known as false memory, but not false memory syndrome. In false memory syndrome, a person erroneously believe that they sustained an emotional or physical (e.g. sexual) trauma in early life. On the other hand, in confabulation person unintentionally fills the gap of me...
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C i.e. Renal aery stenosis Renal retinopathy describes the retinal changes seen in chronic renal failure. These may mimic a hypeensive retinopathy of grade III or IV but the tendency to exudates formation is marked paicularly at the macula.Q Severe hypeension in eclampsia may precipitate a florid retinopathy of grade I...
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GFR = K * EF ....... EF means effective pressure which depends on all pressures mentioned above. Ref: guyton and hall textbook of medical physiology 12 edition:464,465,466
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Synergistic & Antagonistic Muscles (Sherrington's Law) Synergistic muscles are those that have the same field of action. Thus, for veical gaze, the superior rectus and inferior oblique muscles are synergists in moving the eye upward. Muscles synergistic for one function may be antagonistic for another. For example, the...
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This question is a tricky one. The best method does not mean the most accurate method. Best diagnostic test means the test which has high accuracy and less disadvantages. Though invasive pulmonary angiography is the most accurate method for diagnosis of PE, it is an invasive procedure. On the other hand, CT chest with ...
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Ref - Davidsons 23e p1025
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clinical criteria to diagnose neurofibromatosis include 6 or more cafeaelait macules, 2 or more neurofibromas, Freckling in axillary and inguinal regions, Optic gliomas , 2 or more Lisch nodules, A distinctive osseous lesion, A first degree relative with NF1. Page no 322 Reference IADVL's concise textbook of dermatolog...
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Histones are proteins containing unusually higher concentration of basic aminoacids. It functions in the packaging of DNA in the chromosomes. Ref: Vasudevan, Biochemistry, 3rd Edition, Page 345
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The spleen is the most commonly injured abdominal organSabiston 20e pg: 456
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Ans. is 'c' i.e., Vaccination given at 6 months Epidemic of measles occur if propoion of susceptible children is > 40%. If measles is introduced in a virgin community, it infects > 90% of children. Measles vaccine is given at the age of a months, but age can be lowered to 6 months in epidemics. Measles shows a cyclic t...
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Helicobacter pylori was first recognized as a possible cause of gastritis and peptic ulcer by Marshall and Warren in 1984. This organism is readily isolated from gastric biopsies but not from stomach contents. It is similar to Campylobacter species and grows on chocolate agar at 37degC in the same microaerophilic envir...
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Functions of posterior cruciate ligament:Stabilises kneePrevents posterior dislocation of the tibia on femurLimits hyper extension of knee only if the anterior cruciate is rupturedFunction of ACL: Prevents anterior dislocation of the tibia on femur Ref: BDC, 4th Volume, 2/145
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Enterococcus Enterococci cause a wide variety of infections ranging from less serious--for example, urinary tract infections--to very serious, such as septicemia. A gram-positive coccus resistant to penicillin must be assumed to be entero coccus until other, more definitive biochemical testing places the isolate in one...
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pancreas is retroperitoneal. So if it is injured there will be concomitant injury of other viscera.A rise in serum amylase occurs in most cases.Operation is indicated if there is disruption of the main pancreatic duct.Penetrating trauma to upper abdomen or the back carries a higher risk Bailey & Love ,26th edition,1125...
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Hepatitis C infection is usually identified in asymptomatic individuals screened because they have risk factors for infection, such as previous injecting drug use , or have incidentally been found to have abnormal liver blood tests. Although most people remain asymptomatic until progression to cirrhosis occurs, fatigue...
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C i.e. Cyanide
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Ans. is'b' i.e., Nicotinic acid Nicotinic acid (Niacin) There are three main type of lipases related to metabolism of lipoproteins ? Lipoprotein lipase- Present in blood vessels and causes hydrolysis of tryglyceride content of VLDL and chylomicrones. Hepatic lipase - Conves IDL to LDL by hydrolysing the triglyceride co...
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C i.e.Trauma
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Pregnancy is not a contraindication or precaution for Hepatitis B vaccine. Principle: Live-virus vaccines are contraindicated during pregnancy because of the possibility that vaccine virus replication will cause congenital infection or have other adverse effects on the foetus. Must Know - Zoster vaccine is contraindica...
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Ans. is 'd' i.e., Penis
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Selenocysteine is the 21st amino acid.its biosynthesis is by replacing oxygen from serine by selenium.cysteine is formed from serine (reversible). hence selenocysteine is formed from cysteineRef: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 215
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Ans. (d) Vitamin A deficiency style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">Ref: * Major etiological factor: HPV-16 and Tobacco exposure.* 75% of head and neck cancers are caused by tobacco and alcohol use.* HPV type 16: risk factor for oropharyngeal cancers that involve the tonsils ...
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Flaer (Flourescein - Labelled proaerolysin) is sensitive test for PNH.
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11b hydroxylase is not required for estradiol synthesis. Ref: Guyton and Hall 13th edition Pgno: 967
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Ans. is 'a' i.e., CD1A CD1A is a T cell surface antigen impoant in dendritic cell presentation of glycolipids and lipopeptide antigens. It is used to diagnose Langerhans cell histiocytosis. The presence of Birbeck granules in the cytoplasm of tumor cells is characteristic of Langerhans cell histiocytosis. As Birbeck gr...
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Regulation of beta-catenin preventsgenes that stimulate cell division from being turned on too often and prevents cell overgrowth. The humanAPC gene is located on the long (q) arm of chromosome 5 in band q22.2 (5q22.2). The APC gene has been shown to contain an internal ribosome entry site. Refer robbins
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Marxist theory Is concerned with the relationship between health and illness and capitalist social organization – Cause of disease is putting profit ahead of health
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GIANT CELL TUMOR (OSTEOCLASTOMA) It is an aggressive but benign tumor of bone. It is uncommon before age 20 or after 50; 65% of our patients were between ages 20 and 40 years. Giant cell tumors are epiphyseal in origin and they arises after epiphyseal closure. When the lesion is first seen, it is already of good size. ...
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Ans. is 'a' i.e. Tumour Necrosis For histological grading of breast carcinoma three individual factors are assessed.Nuclear pleomorphism Tubule formation Mitotic countThe most commonly used histological grading system is Nottingham histologic score (also k/a Scarff-Bloom- Richardson)
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Release of cholecystokinin is stimulated by the presence of peptides, amino acids, or fatty acids in the small intestine. Cholecystokinin acts on the pancreas to stimulate secretion of pancreatic enzymes that aid in the digestion of these compounds. Gastrin secretion is stimulated by the presence of peptides or amino a...
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Acetyl CoA is the combination of acetate or acetic acid (2 carbon unit) with Co-enzyme A. Acyl CoA means acyl group (any fatty acid, C4 to C26 in length) combined with Coenzyme A.Ref: MN Chatterjea Textbook of Medical Biochemistry, 6th edition, page no: 131
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Ans. is 'c' i.e., Developmental dysplasia of the hip o Two commonly used clinical test for DDH/CDH are:-i) Barlow's testii) Ortolani's testo Barlow's test# Part 1 - Click sound (clunck) of dislocation on adduction.# Part 2 - Click sound (clunck) of reduction on abductiono Ortolanis test# Click sound (clunk) of reductio...
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X-rayshows massively distended transverse colon,ahaustral left colon -History of fever & diarrhea Toxic megacolon: - Life threatening - Occurs in patients of UC and CD . - Diameter > 6 cm - Medical management- Stabilization| Fluids + I/V anti-biotics - TOC - TAC with Ileostomy PMC - No colonic distension, fever & diarr...
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Ans. is 'a' i.e., Dantrolene sodium o I. V dantroline is the DOC, it acts by preventing the release of calcium from sarcoplasmic reticulum. o Others are for suppoive treatment --> oxygen, cooling, and insulin & dextrose are given for hyperkalemia due to potassium release from contracted muscle.
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In lobular carcinoma because: High chance to predispose to invasive carcinoma. 35% of lobular carcinoma in situ may devolop invasive lobular carcinoma either in the same or contralateral breast, 65% may devolop invasive ductal carcinoma. It is multifocal, bilateral(50%). So biopsy from opposite breast should be taken. ...
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Ans. is 'a' i.e., Onchocerca Onchocerciasis (River blindness or Robles disease)o It is caused by Oncocerca volvulus.o Infection in human begins with deposition of infective larvae on skin by the bite of an infected blackfly.o The manifestations are -1) Oiicocercomata: These are subcutaneous itchy nodules over coccyx, s...
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Esophageal varices due to portal hypertension usually bleed without warning or preceding pain. Patients frequently have stigmata of cirrhosis (jaundice and spider angiomata) and portal hypertension (ascites and edema). Blood loss in both Mallory-Weiss tears and esophageal varices can be massive. Hereditary hemorrhagic ...
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Ans. is 'd' i.e., Hallucinations Eugen Bleuler renamed dementia precox as Schizophrenia. He recognized that schizophrenia is a group of disorders rather than a distinct entity. Therefore, he used the term, a group of schizophrenias. Bleuler described the characteristic symptoms (fundamental symptoms) for schizophrenia ...
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NEUTROPHILS AND EOSINOPHILS EMPLOY NETS TO ENTRAP PARASITESIn addition to ingesting small microorganisms such as bacteria by phagocytosis, neutrophils and eosinophils can assist in the elimination of larger invaders by trapping them within webs called neutrophil extracellular traps or NETsRef: Harper&;s Biochemistry; 3...
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NERIUM ODORUM / WHITE OLEANDER contains-oleadrin and nerin resembles digitalis like action REF;THE SYNOPSIS OF FORENSIC MEDICINE:KS NARAYANA REDDY;28th EDITION;PAGE NO355
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Ans. is 'd' i.e., Type IV Collegen type Tissue distributionI-Ubiquitous in hard & soft tissuesII&1X-Cartilage, intervertebral disc, vitreousIII-Hollow organs & soft tissuesIV-Basement membraneV-Blood vesselsVI-Ubiquitous in microfibrilsVII-Dermoepidemal j unctionIX-Cartilage & Vitro us
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Ans. is 'b' i.e., Anesthesia is injected in subarachnoid space * In spinal anesthesia LA is injected into subarachnoid space (space between pia matter and arachnoid matter).* Structure pierced during SA (from outside in) - Skin - subcutaneous tissue - Supraspinous & intraspinous ligament - Ligamentum falvum - Durameter...
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NDRI * IMPOANCE Anti-depressant which does not deal with serotonin neurotransmission Also called as Zyban * MECHANISM Prevents reuptake of nor adrenaline and dopamine * DRUGS Bupropion * USE ADHD SMOKING CESSATION HYPOACTIVE SEXUAL DESIRE DISORDER * SIDE EFFECTS seizures ref, kaplon and sadock, synopsis of psychiatry, ...
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Ans. is 'a' i.e.. Avascular necrosis of femur headClinical features of AVNo In the earlier stages of AVN, the patient is asymptomatic, and by the time patient presents, the lesion is well advanced.o Common histories patient gives (Any of the following) : -i ) Dislocation of HipAlcoholismSteroid intake for any disorderN...
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Large amounts of growth hormone, leads to gigantism in children and to acromegaly in adults. Before pubey, the individual may grow to an extraordinary height. When the epiphyses are closed, linear growth is no longer possible. In this case, an overabundance of growth hormone produces the pattern of bone and soft tissue...
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Pott's puffy tumour is a complication of pyogenic infection of frontal sinus. Pus collects under the periosteum on the anterior surface of the frontal sinus with associated oedema of skin and subcutaneous tissues.
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Answer- A. Mitral stenosisLarge volume hemoprysis, referred to as massive hemoptysis , is variably defined as hemoptysis of greater than 200-600 cc in 24 h. Massive hemoptysis should be considered a medicai emersency.Hemoptysis does not occur from hea failure itself. Most commonly it is due to mitral valve diseases lik...
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Ans. is 'd' i.e., Peripheral decarboxylase Hypolipidemic drugsHMG-CoA reductase iuhibitors (statins) - Lovastatin, Simvastatin, Pravastatin, Atorvastatin, Rosuvastatin.Bile acid sequestrants (Resins) - cholestyramine, colestipol.Activate lipoprotein lipase (fibric acid derivatives) - clofibrate, gemfibrozil, bezafibrat...
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Ans: B i.e. 10 days The earliest sign to appear on the X-ray is a periosteal new bone deposition (periosteal reaction) at the metaphysis. It takes about 7-10 days to appear Osteomyelitis Earliest site of involvement: Metaphysis Diagnosis of acute OM: Blood culture (positive in 65% cases) Periosteal reaction seen in acu...
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Giant cell arteritis (Temporal arteritis) It is the most common form of systemic vasculitis in adults, is an acute and chronic, often granulomatous, inflammation of arteries of large to small size. It affects principally the arteries in the head-especially the temporal arteries—but also the vertebral and ophthalmic ar...
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Ans. is 'd' i.e., Folic acid Assessment of folate deficiencyo Following tests are used for assessment of folate deficiency.Blood levelNormal level in scrum is about 2-20 nanogram/mJ and about 200 micorgram.'ml of packed cells.Histidine load test or FIGLU excretion test :- Histidine is normally metabolized to formimino ...
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Ref Harrison 19 th ed pg 820 Infection most commonly involves hea valves but may also occur on the low-pressure side of a ventricular septal defect, on mural endocardium damaged by aberrant jets of blood or foreign bodies, or on intracardiac devices themselves. The analogous process involving aeriovenous shunts, aerio-...
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Ans. is 'c' i.e., Hypertension Adverse effect of phenytoin|||At therapeutic levelAt high plasma level (dose related)(a) Hypertrophy of gum -commonest in 20%(a) Cerebellar and vestibular manifestation(b) Hirsutism, coarsening of facial features* Ataxia(c) Hypocalcemia* Vertigo(d) Hypersensitivity reactions, these includ...
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Ingestion of mercurous chloridein teething powder has led to acrodynia (Pink disease/Swift disease) in infants. This condition presents as feverwith a pink-coloured rash, irritability, photophobia, painfuland swollen extremities and hypersecretion of sweat glands.It is believed to be a hypersensitivity response to the ...
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Ans. is 'b' i.e., Inhibin o Following are the tests in the identification of Down's syndrome fetus in pregnant women: # Triple test including MS AFP, UE3, total hCG # Quadruple test including MSAFP UE3, total hCG & Inhibin A
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Beta-blockers when given in MI, prevent arrhythmias and also reinfarction.Hence they. increase the morbidity and decrease the moality . patient when discharged is put on beta blockers. REF: KD Tripathi 8th ed.
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Ans. is 'c' i.e.. Closure of aoic valve Aoic pressure curve With the onset of rapid ejection phase of the ventricular systole, the aoic pressure rises steeply to reach a maximum of about 120 mm Hg. The ejection of blood into the aoa causes a stretch on the aoic walls and makes the blood in the entire aerial system to m...
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Ans. Mercury
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Ans. is 'c' i.e., Junction of anterior cerebral aery and anterior communicating aeryBerry aneurysm The fuher away the aneurysm from the anterior circulation or from the circle of willis , the less common will be its rate of occurance.Berry aneurysm or Saccualr aneurysm or Congenital aneurysm is the most frequent type o...
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A patient who has suffered blunt head trauma requiring repeated surgeries for intracranial bleeding will likely be monitored with an intracranial pressure device. Other indications for intracranial pressure monitoring include subarachnoid hemorrhage, hydrocephalus, postcraniotomy status, and Reye syndrome. Measurement ...
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Trachea bifurcates at the lower border of fouh thoracic veebrae. <img src=" /> BA CHAURASIA'S HUMAN ANATOMY VOLUME 1. 6TH EDITION.page no-280
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Ulnar nerve injury will cause paralysis of all interossei, medial two lumbricals, hypothenar muscles, adductor pollicis, FCU and medial two slips of FDP. There is ulnar claw hand (not total claw hand)
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New York Heart Association (NYHA) Classification Importance: Scale used for quantification of degree of functional limitation imposed by Congestive health failure (CHF)
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Ans. is 'b' SLE (Ref. Harrison, 17/e p 2108, 2138, 2139 & 16/e, p 1991, 2021 (15/e, p 1949)).
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Patient in the question suffering from headache since 8 years believes that he has brain tumor despite of all the investigations being normal. His symptoms are suggestive of hypochondriasis. Essential feature of hypochondriasis, is a belief of serious medical illness that persists despite reassurance and appropriate me...
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Meningococcal conjugate vaccine mcv 4 have new largely replaced meningococcal polysaccharide vaccine Mps in prevention of meningococcal dis CDC recommends that all adolescents should recieve meninegiococcal conjugate vaccine MCV 4 IM =1stdose at 12 12 years and booster at 16 years ref : ananthanaryana
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Ans. is 'c' i.e., 6 years Eye in postnatal period Fixation stas developing by 4-6 weeks. Critical period for development of fixation reflex is 2-4 months. Development of fixation is completed by 6 months. So there are three points to remember : ? Fixation stas developing - 4-6 weeks (1-11/2 months). Critical period for...
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PUBERPHONIA (MUTATIONAL FALSETTO VOICE) Normally, childhood voice has a higher pitch. When the larynx matures at pubey, vocal cords lengthen and the voice changes to one of lower pitch. This is a feature exclusive to males. Failure of this change leads to persistence of childhood high-pitched voice and is called puberp...
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Greenish discharge
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