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Microscopically there were collections of "lipidic" cells embedded in the myxoid matrix, typical of cardiac myxoma.</p > Ref:mayo clinic A myxoma is a rare benign tumor of the hea. Myxomas are the most common primary cardiac tumor in adults, and are most commonly found within the left atrium.Myxomas may also develop in...
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Ans. c (100). (Ref. Harrison's internal medicine 16th ed. 528)FAMILIAL POLYPOSIS COLI (FAP)# It is characterized by appearance of thousands of adenomatous polyps throughout the large bowel.# By definition, in FAP at least more than 100 colonic adenomas must be present.# Colonic polyps are rarely present before puberty ...
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Hyperosmolar hyperglycemic syndrome (HHS) is a clinical condition that arises from a complication of diabetes mellitus. This problem is most commonly seen in type 2 diabetes. Won Frerichs and Dreschfeld first described the disorder around 1880. They described diabetic patients with profound hyperglycemia and glycosuria...
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*Multiple myeloma is plasma cells disorder. These plasma cells may have intracytoplasmic inclusion called as Russel bodies and intranuclear inclusions called as Dutcher bodies.
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Ans is 'b' ie Haman's procedure As already explained above, a variety of operations can be done in the obstructing lesion of left colon depending on a variety of factors, but Haman's procedure is the most commonly preferred operation.
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Answer- A. Hirschsprung's diseaseSurgery in Hirschsprung's discase aims to remove the aganglionic segment and'pull-through'ganglionic bowel to the anus (e.9. Swenson, Duhamel, Soave and transanal procedures) and can be done in a single stage or in several stages after first establishing a proximal stoma in normally inn...
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When HR is <60/min even after 30sec of effective Positive Pressure Ventilation and chest compressions, adrenaline is given i.v through umbilical vein at a dose of 0.1 - 0.3 ml/kg in 1:10,000 concentration. Reference : page 132 Ghai Essential Pediatrics 8th edition
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Ans. a. Talonavicular-Calcaneocuboid (Ref: www.vasylimedical.com/pdf/VasyliMedical%20Pronation.pdf)When pronation of the foot occurs, axes of Talonavicular- Calcaneocuboid joints move in parallel direction.'An explanation of the concept of 'unlocking' the foot has been described by Root, Orien and Weed, although the ex...
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Type IV cailage is present in basement membranes Type Distribution I Non Cailaginous connective tissues, including bone, tendon, skin II Cailage, vitreous humor III Extensible connective tissues, including skin, lung, vascular system IV Basement membranes V Minor component in tissues containing collagen I VI Muscle and...
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Rousing's sign is corroborative of acute appendicitis. The other signs are corroborative of appendicitis. Hyperesthesia is a useful sign provided that it is performed objectively. The area of hyperesthesia is a triangular area (base placed upward) in the right lower abdomen.
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Ans. (c) Small cell lung CARef: Robbiris 9th ed./ 717* Azzopardi effect is basophilic staining of vascular walls due to encrustation by DNA from necrotic tumor cells.* It is seen in small cell lung carcinoma
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Craniofacial osteomas are benign tumors often originating in the paranasal sinuses The frontal sinus is the most frequent location followed by the ethmoid, maxillary and sphenoid sinus, respectively Age of presentation = second to fifth decade with a male-femate ratio - 3:1. Presentation: Generally they are an incident...
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Autograft or autologous graft means skin grafts from one site of body to another. They are the best skin grafts.
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There is deep dermal tenderness on application of pressure in secondary syphilis. This is known as an Ollendorff sign or Buschke ollendroff sign.
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In the space there is no gravity. In order to compare the blood pressure taken preflight and the one in the space, BP should be taken in a position where gravity is nullified. In lying position the gravitational force is nullified, so preflight BP measurement should be done in the lying down position. In supine positio...
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Out of the given 4 types of hemolytic anemias only alpha thalassemia is able to give rise to such severe presentation at birth. In all other conditions the newborn is either normal or has mild jaundice.
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Carbon dioxide is the most widely used peritoneal distention medium, because it is non-flammable, colourless and has a higher blood solubility than air & the rapid absorption of CO2 in blood reduces the incidence of gas emboli.
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Option C: Squamous changes to Columnar
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Ans. C: 24 mm The eye of the newborn is hypermetropic and the average axial length is about 18mm.At the age of 3 years it is 23 mm and from age 3-14 years it increases by 1 mm. In the emmetropic eye, the axial length (from the posterior corneal surface to the retina) varies from 22 to 26 millimeters. In the emmetropic ...
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Vegetation in SLE Vegetation in NBTE Small, sterile, firm Both surface of valve Lower surface> upper surface Libman sack endocarditis Marantic endocarditis Along the line of closure Non invasive Don't elicit inflammatory reaction Small, Sterile Friable: Embolism Seen in - Ca Pancreases- AML M3 Vegetation of IE Vegetati...
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Dentate nucleus is associated with Cerebrocerebellum which correspond to lateral zone of cerebellum Ref: Ganong , 25th edition/ page 248
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RNA dependent DNA polymerase
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Ref Harrison 19 th ed pg 1569 Amyloidosis is the major cause of restrictive cardiomyopathy . Several proteins can self-assemble to form the beta-sheets of amyloid proteins, which deposit with differ- ent consequences depending on the type of protein.
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Ans is 'c' i.e. Rodent EdgesUlcerSloppingVenous, TraumaticUnderminedTB, DecubitusPunched outGummatus, Deep trophicRolled upRodent (BCC)Everted (rolled out)see
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Lymphatics from the glans drain into the deep inguinal nodes also called gland of Cloquet. Lymphatics from the rest of the penis drain into the superficial inguinal lymph nodes.Ref: Vishram Singh; Volume II; 2nd edition; Page no: 464
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Glands of Wolfring and Krause are accessory lacrimal glands. They resemble lacrimal gland in structure and function and is located in the conjunctival stroma. Most of the glands of Wolfring lies at the superior margin of the upper tarsus, and most of the glands of Krause lies in the upper fornix. Glands of Zeiss are se...
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Example of larvivorous fish (those that feed on immature stages of mosquitoes) are Gambusia, Poecilia, Aplochelius Ref : Park 23rd edition Pgno : 773
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Ans. is `a' i.e., Hodgkin's lymphomao Hodgkin's lymphoma encampasses a distinctive group of neoplasms that arise almost invariably in a single lymph node or chain of lymph nodes and spread characteristically in a stepwise fashion to the anatomically contiguous nodes.o Therefore staging of Hodgkin's lymphoma not only de...
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Ans. is 'b' i.e., Trichomoniasis o Patients infected with Trichomonas vaginalis complain of a typical discharge, which is thin, profuse, frothy, irritating, creamy or slight green in colour.o Slight green colour of the discharge is often not complained by the patient but spotted by the physiciano The answer cannot be P...
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The angiotensin-converting enzyme normally helps in conversion of angiotensin I to angiotensin II, which acts as a vasoconstrictor in case of hypovolemia. In addition to that, ACE also helps in the breakdown of bradykinin. When ACE inhibitors (captopril) are given, it inhibits ACE and in addition inhibits the breakdown...
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Volume of the orbit is 30ml Orbit" can refer to the bony socket, or it can also be used to imply the contents. In the adult human, the volume of the orbit is 30 millilitres (1.06 imp fl oz; 1.01 US fl oz), of which the eye occupies 6.5 ml (0.23 imp fl oz; 0.22 US fl oz). Ratio of volume of orbit to eyeball is 4.5:1 Ref...
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. Inflammation
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Ans. is 'b' i.e., Hepatitis Bo Important facts regarding different types of vaccine during pregnancy are:-1) Live vaccines: As a rule of thumb all live vaccines are contraindicated during pregnancy. Important ones are measles, mumps, rubella, varicella, BCG, OPV, and yellow fever.2) Inactivated (killed) viral vaccines:...
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Indications for Blood Transfusion To correct anemia due to blood loss and to combat postpaum hemorrhage Patient with severe anemia seen in later months of pregnancy (beyond 36 weeks) Refractory anemia: Anemia not responding to either oral or parenteral therapy in spite of correct treatment Associated infection Referenc...
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Ans: b (M. ulcerans) Ref: Ananthanarayan, 7th ed, p. 367M.ulcerans is the only toxin producing mycobacterium, causing buruli ulcer
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Ans. is 'b' i.e., Thelarche In girls, the first visible sign of pubey is the appearance of breast buds (Thelarche), between 8-12 years of age. In boys the first visible sign of pubey is testicular enlargement, beginning as early as 91/2 yr.
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Febuxostat is a non purine inhibitor of xanthine oxidase which is required for oxidation of hypoxanthine and xanthine to uric acid. It is usually used in gout especially in patients who are intolerant to allopurinol. Other drugs used in the treatment of hyperuricemia: Uricosuric drugs Probenecid Sulfinpyrazone Uric aci...
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ANSWER: (B) Paramesonephric ductREF: Langman s medical embryology 9th ed p. 340-341Repeat Anatomy December 2011See APPENDIX-5 for "ADULT DERIVATIVES AND VESTIGIAL REMAINS OF EMBRYONIC UROGENITAL STRUCTURES" APPENDIX - 5Adult Derivatives and Vestigial Remains of Embryonic Urogenital StructuresEmbryonic StructureMaleFema...
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Ans. is 'd' i.e., Hypertonia Features of neonatal hypothyroidismo Neonate is normal at birth due to presence of maternal thyroid hormones.o First clinical sign is prolongation of physiological jaundice due to delayed maturation of glucuronide conjugation.Other features are:-o Open posterior fontanel and wide sutureso L...
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Ref-KDT 6/e p758 Newer liposomal preparations of amphotericin B have the following features: Less chances of nephrotoxicity and infusion related reactions Lesser uptake in the tissues like kidney More expensive Similar in efficacy and antifungal spectrum as conventional preparations
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Amyloidosis is the extracellular deposition of insoluble protein fibrils. AL- Primary systemic amyloidosis AA- Secondary amyloidosis AF- Familial Aβ2M- In ESRD Diagnosed by abdominal fat pad aspiration showing apple green birefringence by polarized light microscopy with Congo red stain High ESR, High ALP Serum Immunofi...
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A concept that may be used to reduce shrinkage stress is the use of “soft-start” polymerization. This approach utilizes a number of procedures to prolong the gel phase of the setting reaction of the composite resin material. The theory is that the longer the setting composite can maintain a gel or flowable condition, t...
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Dupuytren's contracture (contracture of palmar aponeurosis)a. It is characterized by flexion deformity of one or more fingers due to the thickening and shoening of the palmerb. aponeurosis.c. Etiology:i. Unknownii. Hereditary predispositioniii. Cirrhosis of liveriv. Epileptic patients on phenytoind. The fingers are dra...
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Ans. is 'c' i.e., Right renal vein shorter than left renal vein Renal vasculatureo Each kidney is supplied by renal artery {branch of abdominal aorta) and is drained by renal vein to IVC.o Renal artery Right renal artery is longer and passes behind JVC. Renal artery divides into : -Posterior division Supplies posterior...
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The single most impoant prognostic factor is lymph node status:5-year survival without groin node metastases is greater than 90%; with groin node metastases, 5-year survival is 50%. Inguino-femoral lymph nodes are involved in stage iii whereas pelvic and other lymph nodes are involved in stage iv A and hence pelvic lym...
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Acrodermatitis enteropathica is an autosomal recessive disorder postulated to occur as a result of mutations in the SLC39A4 gene located on band 8q24.3. The SLC39A4 gene encodes a transmembrane protein that is pa of the zinc/iron-regulated transpoer-like protein (ZIP) family required for zinc uptake. This protein is hi...
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Answer is A (Suprapubic aspiration) Urine obtained from suprapubic aspiration is least likely to be contaminated- Suprapubic aspiration avoids potential contamination but is rarely used because of its invasiveness It may be indicated in children2 (and selected other patients) Desirable propeies of a voided sample It is...
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Ans. is 'd' i.e., >100 Familial adenomatous polyposis* This autosomal dominantly inherited condition is characterized by the development of multiple rectal and colonic adenomas around puberty.* It is due to mutation of the adenomatous polyposis coli (APC) gene, allowing genetic testing in the 75 percent of families in ...
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Massive hemoptysis is generally defined as expectoration of over 600 mL of blood within a 24hour period. It is a medical emergency associated with a moality rate of 30 to 50%. Ref: Harrison; 20th edition pg 233
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A i.e. DNAHereditary information is preserved in DNA. Thus all genetic diseases are due to change in DNAQ.
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McMohan and Pugh
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* All the symptoms of hypoglycemia are blocked by beta blockers except sweating as it has cholinergic innervation * Beta blockers (non selective) are contraindicated in : ABSOLUTE C/I Pheochromocytoma Decompensated hea failure symptomatic bradycardia AV block Asthma RELATIVE C/I Peripheral vascular disease
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b. Pronator quadratus is attached to the radius and ulna and lies against the anterior surfaces of these bones. Explanationsa. The median nerve is found on the deep surface of flexor digitorum superficialis muscle, to which it is usually bound with fascia. c. The Ulnar nerve lies under flexor carpi ulnaris with the uln...
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The aim of active immunisation with tetanus toxoid is to vaccinate the entire community and ensure a protective level of antitoxin approximately 0.01 IU/ml serum throughout life Reference; Park&;s Textbook of preventive and social medicine, 24th edition.Pg no. 330
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- Given patient has increased coisol & ACTH levels with cushingoid signs & symptoms. - This could result from either functional ACTH-secreting tumor in pituitary (Cushing's disease) or an ectopic tumor (such as a small cell carcinoma of lung, choice B). - To distinguish b/w these two,high doses of potent synthetic gluc...
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human mitochondrial DNA is a double-stranded circular molecule containing approximately 16,500 base pairs.(REF: GANONG'S REVIEW OF MEDICAL PHYSIOLOGY 23rd EDITION page no.34.)
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A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide range of effects, from mild sedation to death . The kinetics of barbiturate elimination are mixed: first order at low concentrations and zero order at high ones Ref-6/e p31
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PYRIFORM FOSSA: It is a deep recess broad above and narrow below in the anterior part of lateral wall of the laryngopharynx, on each side of the laryngeal inlet.  These recesses are produced due to bulging of larynx into laryngopharynx. Boundaries: Medial: Aryepiglottic fold and quadrangular membrane of larynx. Lateral...
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Chlorthiazide is a thiazide diuretic which can lead to hyper uricema, as Thiazide diuretics competitively inhibit excretion of uric acid.
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Characteristics includelarge, soft, friable, easily detached vegetations consisting of fibrin and intermeshed inflammatory cells and bacteria. Complications may includeulceration, often with perforation, of the valve cusps or rupture of one of the chordae tendineae. 2. Classification Acute endocarditis is caused by pat...
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Ans. is 'c' i.e., Highly selective vagotomy It is least seen with highly selective vagotomy because the motility of the stomach is least affected in highly selective vagotomy and is most common with gastrectomy.
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Ans. Avulsion
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Ref: KV Krishna Das - Clinical Medicine 4th Edition pg no:175-176 Right sided hea failure is accompanied by systemic venous congestion and peripheral edema, whereas left sided hea failure is accompanied by pulmonary venous congestion and pulmonary edema. Dependent edema, paicularly prominent towards evening is a charac...
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Osmotic pressure is determined by the number of molecules dissolved in a fluid rather than by the mass of these molecules. Therefore, when corrected for number of molecules rather than mass, the following chart gives both the relative mass concentrations (g/dl) of the different types of proteins in normal plasma and th...
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* IV KCl - Never given as bolus as it can cause Diastolic arrest. * Always given diluted and advised to give diluted in saline.
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Ans. is 'd' i.e., Pentothenic acid VitaminActive form (coenzymes)Reaction typeB1 (Thiamin)Thiamine pyrophosphate (TPP)Oxidative decarboxylation, TransketolationB2 (Riboflavin)FMN, FADOxidation / Reduction (Redox reaction)B3 (Niacin)NAD+, NADP+Oxidation / Reduction (Redox reaction)B6 (Pyridoxin)Pyridoxal phosphate (PLP)...
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Carbamoyl phosphate synthase 1 conve CO2 + NH4 to Carvomyl phosphate Ref-Harpers illustrated biochemistry 30/e p680
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In contrast in Adrenal insufficiency weight loss occurs Ref - Davidson's medicine 23e p672 , ( Harrison 17 pg 2263)
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Under resting conditions, the concentrations of sodium and chloride ions in the saliva are only about 15 mEq/L each, about one-seventh to one-tenth their concentrations in plasma. Conversely, the concentration of potassium ions is about 30 mEq/L, seven times as great as in plasma, and the concentration of bicarbonate i...
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Cerebellar astrocytomas donot show any clear gender predilection and are equally common in both males and females. Cerebellar Astrocytomas MC astrocytomas in childhood are low grade astrocytomas Juvenile pilocytic Astrocytoma (JPA) is MC astrocytoma in children Cerebellar Astrocytoma (JPA) donot show any clear gender p...
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Leprosy: Oldest disease known. Caused by Mycobacterium leprae. Mode of transmission: Air droplets, skin contact, transplacental, breast feeding, insect bite, tattoo, corneal/organ transplantation. Mycobacterium leprae has no aificial culture media. Leprae bacilli are cultured by: Foot pad of mice. 9-banded armadillo. O...
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Ans. is 'b' i.e., Increased breath sounds Physical examination findings of Common pulmonary conditions Pleural effusionPneumoniaEndobronchial tumorPneumothoraxTracheal positionChest wall movementFremitusPercussionBreath soundsCracklesWheezeShifted or midtineReduced or normalDecreasedDullDecreasedNoneNoneMidlineReduced ...
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D. i.e. Temerature
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ECG changes- flattened T wave, a depressed ST segment & appearance of a U wave- seen in Hypokalemia
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FMA and its relationship with IMPA: Tweed observed that patients whose FMA was more than 30 degrees demonstrate nature’s way of compensating for inclination of the mandibular incisors to the mandibular plane. The IMPA was found to be as little as 77 degrees and the FMIA to be around 65 degrees. The occlusal plane conve...
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In most patients laryngomalacia is a self-limiting condition. Treatment of laryngomalacia is reassurance to the parents and early antibiotic therapy for upper respiratory tract infections. Tracheostomy is required only in severe respiratory obstruction. Surgical intervention (supraglottoplasty i.e. reduction of redunda...
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Usage of GnRH agonists : Pulsatile GnRH agonist Non pulsatile (continuous) GnRH agonist Delayed pubey Ovulation induction Kallmann's syndrome Male infeility Endometriosis Hirsutism Uterine fibroids Central precocious pubey Prostate cancer Breast and ovarian cancer Note : Non-pulsatile administration of GnRH agonist is ...
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Ans. is 'a' i.e., AEC inhibitors o ACE inhibitors are now drug of choice for initial management of hea failure.o Loop diuretics (furosemide) are the DOC for acute hea faiure.o Though the ACE inhibitors are the DOC for chronic HE, diuretics are given to almost all the patient initially to relieve congestive symptoms.
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B i.e. Atracurium besylate
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Ans. D. Phencyclidine (PCP)Abused drug - Synonym/manifestation* Methylenedioxymethamphetamine. MDMA: Rave drug/Ecstasy.* LYSERGIC ACID DIETHYLAMIDE (LSD): "bad trip"* Methamphetamine: Also called "meth," "speed," "crank," "chalk," "ice," "glass," or "crystal."* Phencyclidine (PCP): "Angel dust"* MARIJUANA (CANNABIS): D...
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Pseudo-koebner's phenomenon is seen in plane wart, molluscum contagiosum and eczematous lesions.
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Primary supports of Uterus -        Muscular support    Pelvic diaphragm (Levator ani), urogenital diaphragm, perineal body. -        Mechanical support    Uterine axis, pubocervical ligament, Mackenrodt ligament, uterosacral ligament, round ligament of the uterus.
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Ans. is 'd' i.e., Humidity Instruments MeasureSling psychrometer} Assmann psychrometerHumidityDry & wet bulb hygrometer Kata thermameter-Cooling power and air velocityGlobe thermameter-Radiant tempratureAnemometer-Air velocityWind vane-Wind (air) directionSound level meter-Intensity of soundBond frequency analyzer-Char...
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Ans. C. Oral contraceptivea. The given USG suggests molar pregnancy as it is showing snowstorm appearance.b. IUCD/POP can cause irregular bleeding/spotting.c. Barrier methods have high failure rates.d. OCP are ideal for post molar contraception.
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Band of baillarger is horizontally running myelinated nerve fibers present in cerebral cortex, due to which visual cortex is referred to as striate cortex. Outer band is present in inner granular layer (layer no-4), and inner band is present in inner pyramidal layer (layer no-5)
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CoA biosynthesis requires cysteine, pantothenate (vitamin B5), and adenosine triphosphate (ATP).it is naturally synthesized from pantothenate (vitamin B5), which is found in food such as meat, vegetables, cereal grains, legumes, eggs, and milk.Pantothenate (vitamin B5) is phosphorylated to 4'-phosphopantothenate by the...
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Fever on post-operative day 3 after laparoscopic splenectomy suggests left lower lobe consolidation. Left lower lobe atelectasis Most common complication after Open Surgery; Pleural effusion and pneumonia also can occur. Hemorrhage can occur intra-operatively or postoperatively, presenting as subphrenic hematoma. Trans...
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It is a dominantly inherited dystrophy of endothelium and Descemet's membrane. It is characterised by lesions with variable appearance, such as vesicles, curvilinear lines or geographical opacities at the level of Descemet's membrane. The condition is very slowly progressive and thus usually asymptomatic. Corneal oedem...
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Faecal occult blood testing of people aged 60-69 years, followed by colonoscopy in those who test positive. A guaiac-based test is used, which detects peroxidase-like activity of faecal haematin. Studies have suggested a 15-20% reduction in colorectal cancer-specific moality in the screened population. Flexible sigmoid...
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Unlike the low solubility products of purine catabolism, catabolism of the pyrimidines forms highly water-soluble products-- CO2, NH3, b-alanine, and b-aminoisobutyrate (Figure 33-12). Humans transaminate b-aminoisobutyrate to methylmalonate semialdehyde, which then forms succinyl-CoA (see Figure 19-2). Excretion of b-...
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Autoclave: Recommended condition- 121–124°C temperature for 15 min at 1.1 bar pressure Alternate: 134–138°C temperature for 3 min at 2.2 bar pressure Hot air oven: 160°C temperature for 120 min or 180°C temperature for 30 min
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cAMP undergoes rapid hydrolysis catalysed by the enzyme phosphodiesterase, to 5'AMP which is inactive. Caffeine and theophylline can inhibit phosphodiesterase and increase the intracellular levels of cAMP.
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Ringer lactate is preferred agent for resuscitation for the initial 24 hours Nasogastric intubation is done to decrease the risk of emesis and possible aspiration (as paralytic ileus develops in the patients of burn) Dextran is a colloid and can be used after 24 hours however, albumin is the preferred and most widely u...
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Ans. is 'b' i.e., Women in reproductive age group in a given year
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Linezolid is Oxazolidinone. MOA: It inhibits protein synthesis by preventing formation of the ribosome complex that initiates protein synthesis by binding to 23S ribosomal RNA of the 50S subunit. It is active against Gram positive organisms including Staphylococci, Streptococci, Enterococci, Gram positive Anaerobic coc...
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Ovarian cycles consists of the following : recruitment and growth of the follicles, ovulation, corpus luteum formation and finally regression of corpus luteum. Along with changes in the ovary there are simultaneous changes in the uterus - the menstrual cycle. Endometrial sampling revealing proliferative or secretory en...
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Ref-Katzung 11/e p952 Anthracyclines (daunorubicin, doxorubicin, epirubicin and idarubicin)can cause severe cardiotoxicity manifesting as dialted Cardiomyopathy and arrhythmias. The anthracycline chemotherapeutic agents (doxorubicin, daunorubicin, epirubicin and idarubicin) form free radicals in the myocardium. Their m...
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Ans. is `d' i.e., All
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Ans. Consists of lymphocytes, plasma cells, epitheloid and giant cells
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