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Ans. is 'b' i.e., Deltoid and teres minor Axillary nerve (circumflex nerve)* Axillary nerve is a branch of the posterior cord of brachial plexus with root value C5 and C6.* It leaves the posterior wall of axilla along with the posterior circumflex humeral vessels throuth the quadrangular space. While passing through th...
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Probability is a chance that an event will occur and it lies b/w 0 to 1 (0-100%). For mutually exclusive events , probability is calculated by rule of addition P=P+P. For independent events, joint probability is calculated by rule of multiplication P=PxP. Given, probability of having a baby with bih weight >= 3000 gram...
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Continued corpus luteum function depends on continued LH production. In the absence of this stimulation, the corpus luteum will invariably regress after 12 to16 days and form scar-like corpora albicans. In the absence of pregnancy, the corpus luteum regresses, and estrogen and progesterone levels wane. If pregnancy occ...
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Ans. Alternate procedures/treatment to be concealed from the patients
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• Saddleback fever: Two peaks of fever separated by an afebrile period in-between • Seen in: Dengue, Trench fever, Bartonellosis, Chikungunya, Colaradotick fever • Saddleback fever: Two peaks of fever separated by an afebrile period in-between • Seen in: Dengue, Trench fever, Bartonellosis, Chikungunya, Colaradotick fe...
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Answer is B (Anemia of chronic disease) Hypochromic microcytic anemia with decreased serum iron and decreased TIBC is characteristic of anemia of chronic disease. Hypochromic microcytic anemia with 4.serum iron and TTIBC: iron Deficeincy Anemia Hypochromic microcytic anemia with fserum iron and TIBC : Anemia of Chronic...
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The omentum and peritoneal cavity seem to be less efficient in localizing the disease in these age groups. Appendicitis has a particularly high-complication rate in infants and the elderly. Delay in establishing the accurate diagnosis in these two age groups also contributes to a worse prognosis.
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This is the history of neonatal herpes that manifests as a generalized infection in the neonate. Most common cause is HSV2. HSV2 is the most common cause of genital herpes, which manifests as painful vesicular lesions that ulcerate. The site of latent infection is sacral nerve root ganglia.
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Ans. is 'c' i.e., AcetylcholineLower esophageal sphincter Unlike the rest of the esophagus, the musculature of the gastroesophageal junction (lower esophageal sphincter; LES) is tonically active but relaxes on swallowing.The tonic activity of the LES between meals prevents reflux of gastirc contents into the esophagus....
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Warfarin acts by inhibiting the activation of vitamin K dependent clotting factors- directly inhibiting Vit K epoxide reductase These factors include clotting factors II, VII, IX and X.
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The most common locations of hypeensive ICH are: 1) Basal ganglia (putamen or caudate), 2) Thalamus, 3) Pons and 4) Cerebellum. Within the basal ganglia region, it is rare for an ICH to specifically affect one area; Ref Harrison20th edition pg 2345
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Lateral walls of vaginaThe upper one third is related with the pelvic cellular tissue at the base of broad ligament in which ureter and uterine aery lie approximately 2cm from lateral fornicesThe middle third is blended with levator ani The lower third is related to bulbocavernosus muscle, vestibular bulbs and Baholin ...
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Answer- B. Loss of corneal reflexAbsent corneal reflex is the earliest sign of cerebellopontine (CP) angle tumors like acoustic neuroma.
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Higher concentration of retinol increases the synthesis of lysosomal hydrolases. The manifestations of hypervitaminosis A are attributed to the destructive action of hydrolases, particularly on the cell membranes. Ref : Satyanarayana, 3rd ed, pg no.123
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Refer kDT 7/e 529 Class III agents have the potential to prolong the QT interval of the EKG, and may be proarrhythmic (more associated with development of polymorphic VT). Class III agents include: bretylium, amiodarone, ibutilide, sotalol, dofetilide, vernakalant and dronedarone
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Ans. is d i.e. Shoulder Well friends, lets quickly see some impoant terminologies. Lie : It is the relationship between the long axis of the fetal ovoid to the long axis of the uterine ovoid. The lie can be (1)longitudinal, (2) transverse or (3) oblique. The commonest is longitudinal seen in 99.5% cases. Presentation :...
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Ans. is 'd' i.e., DEC acts on adults, and Ivermectin on microfilariae o No option in this question is absolutely correct because ? 1. Diethyl - carbamazine (DEC) is effective against both the microfilariae of peripheral blood as well as the adult worm. 2. Ivermectine is effective only against microfilarae without affec...
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Clinical manifestations of congenital hypertrophic pyloric stenosis Pyloric stenosis is usually not present at birth. Nonbullous vomiting is the initial symptoms of pyloric stenosis. The vomiting usually starts after 3 weeks of age, but symptoms may develop as early as the 1st week of life and as late as the 5 months...
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Pulmonary stenosis produces Ejection systolic murmur. It stas after S1, peaks at mid-systole and ends before S2. Best heard in pulmonary area. Ref: Harrison&;s 20th edition pg 1445
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B i.e. Total body water
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The classic triad for opioid poisoning is miosis, coma and respiratory depression. Naloxone is a potent antagonist and does not cause respiratory or circulatory depressant action. The aim of naloxone administration is to reverse the respiratory and central nervous system depression. REF;THE SYNOPSIS OF FORENSIC MEDICIN...
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Capsule of cryptococcus neoformans in a CSF sample is best seen by India ink preparation. Gomori methanamine stain, PAS stain and Alcian blue stain are also used in identifying this organism. Ref: Handbook for Zoonotic Diseases of Companion Animals By Glenda Dvora, 1st Edition, Pages 108-9
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Ans. (C). Lower part of legs & handsLivor mortis is seen in the dependent parts of the body.In the suspended position of hanging, the dependent parts are lower part of legs and hands.This pattern of distribution is termed as Glove & stockings distributionQ
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In grade 1 hypeensive retinopathy It consists of mild generalized aeriolar attenuation, paicularly of small branches, with broadening of the aeriolar light reflex and vein concealment. Ref Comprehensive ophthalmology AK Khurana 4th edition page no 258
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(A) Secretion of anterior pituitary hormones is pulsatile # Secretion of anterior & posterior pituitary hormones, adrenal glucocorticoids, mineralocorticoids and catecholamines, gonadal sex steroids, parathormone, insulin and glucagon is pulsatile (burst-like or episodic).> Neuronal inputs, cellular excitability and fe...
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- Following conditions are seen in patients of GRAVES DISEASE or HYPEHYROIDISM. Upper eye lid signs Von graefe's sign- lid lag on downgaze Dalrymple's sign - lid retraction Stellwag's sign- incomplete & infrequent blinking Grove sign- resistance to pulling the retracted upper lid Boston sign- jerky movements of lid on ...
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Hering-Breuer Reflex: Receptor: Pulmonary stretch receptors lie within the smooth muscle of large and small airways (bronchi and bronchioles). Stimulus for receptor: Distension of the lungs, when TV is more than 1.5 L Afferent: Vagus nerve large myelinated fibers. The Hering-Breuer inflation reflex (also called inhibit...
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Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of b...
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MCV-Mean cell volume is the average volume of a red cell in femtolitres.ie it measures the size of RBC MCHC -Mean cell hemoglobin concentration is the average concentration of haemoglobin in given volume of packed RBC expressed in grams per decilitre. MCH -Mean cell hemoglobin is the average content of Hb per red cell ...
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Ans. (b) Absence seizure.The EEG shows a typical 3/sec spike and generalized wave discharge.Note: Complex (atypical) absence seizures have associated motor components consisting of myoclonic movement of the face, fingers, or extremities and, on occasion, loss of body tone.
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Ans. is 'a' i.e., Neurofibromatosis 1 o Optic nerve glioma (astrocytoma) is the most common intrinsic tumor of the optic nerve. Most common type of optic nerve glioma is juvenile pilocytic astrocytoma The majority of optic nerve gliomas are of astrocytic origin. However, a few rare optic nerve gliomas arise from oligod...
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Ans. Prodrome
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New DNA strands are synthesized by Taq polymerize, this enzyme is derived from bacteria Thermus aquaticus , that are found in hot springsTherefore enzyme is not denatured at high temperature The polymerize reaction is allowed to take place at 72*c for 30 seconds in the presence of dNTPsRef: DM Vasudevan, 7th edition, p...
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Gonococcal inflammation usually begins in the Baholin glands and other vestibular glands or periurethral glands. The adult vagina is markedly resistant to gonococci, but in child because of more delicately lining mucosa vulvovaginitis may develop Ref: Robbins and Cotran Pathologic Basis of Diseases, 7th edition, page n...
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Erythropoiesis : 1st trimester - in mesoderm of yolk sac (Mesoblastic stage); 2nd trimester - liver & spleen (Hepatic stage); 6 months onward - bone marrow (Myeloid stage). At bih - all bones have red bone marrow, producing cells. Progressively, bone marrow turns yellow; shafts of long bones first turn yellow, followed...
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Ans. is 'd' i.e., HRCT * HRCT is the investigation of choice for bronchiectesis* The CT criteria for diagnosis include 'signet -ring' sign (bronchus being larger than accompanying vessel), bronchial wall thickening, and bronchi visible within 1 cm of the pleura.* Three types are described according to Their appearance ...
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Exhumation is to be carried out under the orders of the appropriate authority. District Magistrate/Sub-Divisional Magistrate/Executive Magistrate are empowered to order for the exhumation. Ref : Krishnan vij Textbook of Forensic medicine and Toxicology 5th edtion ; pg no - 28
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Clostridium difficile
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Answer is D (None: All are Features of Acute severe Asthma) : Tachycardia (HR>120/min). PEFR < 50%, Pulsus paradoxus and Respiratory Acidosis are all features of Acute severe Asthma.
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After exiting the circulation, leukocytes move in the tissues toward the site of injury by a process called chemotaxis, which is defined as locomotion along a chemical gradient. Both exogenous and endogenous substances can act as chemo-attractants.
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Ans. is 'c' i.e. Parallel rays of tubular structure in lysosomeRef.: Robbin 6th/e p158, Oxford medicine 3rd/e p1927, Oxford Patho 5th/e p 1361First about PAS staining -PAS stain - It is a widely used stain to demonstrate polysaccharide in cells. So cells containing glycogen are strongly positive with PAS. However PAS a...
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Right coronary aery is smaller than the left coronary aery. It arises from the anterior aoic sinus. Left coronary aery is larger than the right coronary aery. It arises from the left posterior aoic sinus. REF : B D Chaurasia's Human Anatomy , seventh edition , volume 2 , pg.no., 278, 279. FIG REF : B D Chaurasia's Huma...
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Spasmodic dysmenorrhoea is another name for primary dysnenorrhoea. (i.e. no pelvic pathology is responsible for pain) Characteristics of spasmodic dysmenorrhoea • Seen in adolescent girls • Pain appears within 2 years of menarche • Family history may be present • Pain is spasmodic nature. It is located in lower abdomen...
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Immune Recovery Uveitis With initiation of HAA, there is an upregulation of pro-inflammatory cytokines like IL-2, IL-6 and TNF alfa and the T lymphocycte fraction (increase to range of 100 cells/mm3). Present understanding is that with increase in the body's mechanism to mount an immune response, the body mounts a resp...
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Ans. (b) Subphrenic abscessRef: Bailey 26th edition Page 977* Bailey says- "Pus Nowhere, Pus Some where- search Pus Under the Diaphragm"* In a post op case (patient lying)- most dependent site of abscess formation is Subphrenic Space
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Clostridium septicum: citron bodies, boat or leaf-shaped polymorphic bacilli. Motile by peritrichous flagella. Saccharolytic and produce abundant gas. Produce alpha, beta, delta and gamma toxin. Causative of gas gangrene, braxy or malignant edema. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th e...
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Ans: D (1000 ml) Ref: Nelsons Textbook of Pediatrics. 19th Edition & OP GHAI, Textbook of Pediatrics; 7th edition, page: 267Explanation:According to WHO guidelines for management of severe dehydration lOOml/kg of intravenous fluid should be tiiven.AGEFIRST GIVETHEN GIVE<12 months30 ml/kg in 1 hour70ml/kg in 5 hours12mo...
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. Amyloidosis
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Ans. is 'a' i.e.. Renal vasodilatation o Dopamine produces dose dependent action: At low dose (1-2 mg/kg/min) causes dilation of renal and mesentric vessels - often referred as renal dose:At moderately high dose (2-10 pm/kg/min) produces a positive ionotropic effect by stimulating b1 receptor on heart - cardiac dose.At...
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Ans. A: Increased HbA2Haemoglobin electrophoresis in beta-thalassemia minor usually reveals an increase in HbA2 (alpha2, gamma2) to 4-8% of the total hemoglobin (normal 2.5%)
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Dimple sign is seen in Dermatofibroma Dermatomyositis is characterized: Gottron sign: violaceous eruption an metacarpal or interphalangeal joints. Heliotroperash: Pink to violaceous erythema over periorbitalarea.
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Tetralogy of fallot Commonest cyanotic congenital hea disease in children above the age of two years constituting almost 75 % of all blue patients. Four constituents of tetra logy as described originally by Fallot consist of :- * 1. Ventricular septa! defect (VSD) # 2. Pulmonic stenosis # 3. overriding or dextroposed a...
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Ans. is 'a' i.e., Osteoporosis Raloxifeno Raloxifen is a recently introduced selective estrogen receptor modulator (SERM)Mechanism of action:Partial agonist inAntagonist action ino Boneo Endometriumo Cardiovascular systemo Breasto It has high affinity for both ER a and ER bo It has a distinct DNA target: 'Raloxifence r...
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Ans. is c' i.e., Abducent nerve o Inability.' to move the eye outward beyond midline suggests lateral rectus palsy, which is responsible for abduction. There are six extraocular muscles in each eye.o All the extra ocular muscles are supplied by the occulomotor nerve except for the superior oblique which is supplied by ...
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All Correct : Ovalbumin, Ferritin, Glutelin > Myoglobin Ricin is a phytotoxin. Whereas , ovalbumin, ferritin and glutelin are storage proteins.Hepcidin is the chief regulator protein known to play a central role in systemic iron hemostasisQ. It bind to cellular iron expoer ferropoin and triggers its internalization and...
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Ans. is 'c' i.e., OCD
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Ans. Alcohol
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Common causes of median nerve palsy in carpal tunnel are carpal tunnel syndrome (most common) and Innate dislocation. REF : Maheshwari book of ohopedics 9th Ed.
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Procedural Memory includes skills and habits, which, once accquired, become unconscious and automatic. This type of memory is processed in the striatum. Implicit Memory/Non-declarative memory: It doesnot require being conscious or awareness. Eg., Remembering how to brush your teeth. They are of 4 types: Procedural memo...
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Thyroglossal cysts are the most common cause of midline neck masses. Can occur anywhere along the path of the thyroglossal duct, from the base of the tongue to the suprasternal notch (in the midline) Treatment must include excision of the whole thyroglossal tract, which involves removal of the body of the hyoid bone an...
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A i.e. Common peroneal nerve Smallar terminal branch of sciatic nerve, the common peroneal (lateral popliteal) nerve arises in the lower third of thigh. It runs down ward through the popliteal fossa (lateral side) closely following the medial border of biceps femoris muscle. It leaves the fossa by crossing superficiall...
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Answer is B (Hydrochlohiazide) Hydrochlohiazide is not a preferred agent for the treatment of hypeension in diabetics as it causes unorable alteration in glucose and lipid profile of the patient. `Hyperglycemia and hyperlipidemia have been repoed with the use of diuretics as antihypeensives' -- KDT Antihypeensive drugs...
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A- Anterior hip dislocation B- Posterior hip dislocation C- Fracture neck of femur D- Gluteal muscle hematoma Posterior hip dislocation Due to deceleration injury Here the left knee was forcefully impacted the vehicle's dashboard, forcing the femoral head posteriorly over the rim of the acetabulum. As he turned to reac...
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Ans. is d i.e., Maltose Triple sugar iron agar is used for the differentiation of microorganisms on the basis of :? Fermentation of dextrose (glucose), lactose and sucrose. Production of H2S. It is recommended for differentiation of enteric gram negative bacilli from clinical specimens, dairy samples and food products....
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Ans: A (ELISA) & D (Western blot) "In western blots (also called immunoblots) protein molecules in the sample are separated by electrophoresis & blotted (transferred) to a membrane. The probe is a labeled antibody, which produces a band at the location of its antigen"- Lippincott's Biochemistry 4th/484Table (Lippincott...
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- Prone ventilation is not a mode of ventilation - Means patient put on prone position and ventilated Prone position ventilation- Has improved oxygenation of patient- Cannot be tried for long hours- Practiced when moderate or severe ARDS is suspected in patient- When patient put in prone way the dorsal surface of the l...
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Ans. is 'a' i.e. Adenocarcinoma Barret's esophagus is the single most important risk factor for adenocarcinoma of esophagus.Barret's esophagus is metaplastic change of distal esophageal mucosa from normal squamous epithelium to columnar epithelium, in response to chronic gastro-esophageal reflux.The junction between sq...
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NEERI DEVELOPED A TECHNIQUE FOR REMOVING FLUORIDE BY CHEMICAL DEFLOURIDATION OF WATER CALLED NALGONDA TECHNIQUE. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 596
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Inv(16)(p13q22) and t(16;16)(p13;q22), that we refer as inv (16) and t(16;16) respectively from now, are recurring chromosomal rearrangements commonly associated with the M4Eo subtype of AML but also repoed in the AML M2, M5 subtypes, and in patients with morphological features of higher risk MDS Ref Davidson 23rd edit...
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Ans. (a) Eale's diseaseRef: Pearson's 22/e, p. 344Eale's disease is characterized by recurrent bilateral vitreous hemorrhage in young adult (20 - 30 yrs) males.
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It is seen in Orbital blowout fractures where orbital floor is fractured. 3 factors responsible for enopthalmos : Escape of Orbital fat into maxillary sinus. Backward traction on the globe by entrapped inferior rectus muscle. Enlargement of orbital cavity from displacement of fragments. Ref: AK Khurana 6thE pg423
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Unilateral elavator palsy caused by an involvement of inferior rectus muscle. Ref . Ak khurana 6th edition pg no 414
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Ans. is 'b' i.e., Opacification of posterior capsule "Opacification of the posterior capsule caused by proliferation of cells in capsular bag remains the most frequent complication of ECCE and IOL surgery". Vajpayee
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Athetosis is involuntary movement, but can’t be suppressed voluntarily
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. Methylation of Tumor suppressor genes
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Migraine prophylaxis should be considered in patients who: * suffer at least two attacks a month; * are experiencing an increasing frequency of headaches; * The prophylaxis should not be continued for more than 4-6 months. * Therapy for migraine prophylaxis should aim to reduce the frequency of migraine attacks by 50% ...
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HEAT RUPTURE: If the heat applied is very great skin contracts and heat ruptures occur either before or after death. they are produced by splitting of the soft pas these splits may be anywhere but are usually seen over extensor surfaces joints and on the head These ruptures or splits of the skin may be several centimet...
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Ans: A (Mediastnal lymph node biopsy) Ref: Harrisons Textbook of Internal Medicine. 17th ed, chapter 322; Fishman's textbook of Pulmonary Diseases and Disorders, 4th ed pg: 1126-1134Explanation:Patients are usually evaluated for possible sarcoidosis based on two scenarios. In the first scenario, a patient may undergo a...
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Ans: (a) Causes nephropathy in transplant patientsRef: Harrison, 19th editionBK VirusBK virus is a non-enveloped double-strand DNA virus which belongs to family polyoma viridae.Primary BKV infection occurs by the upper respiratory route until age 10 without any obvious symptoms.80% of the population is infected by BKV,...
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Ans. C i.e. Monteleukast
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ANSWER: (A) Lengthening of muscle fibreREF: Ganongs 22nd edp. 572Preload is determined by amount of blood reaching the heart; it causes an increase in the muscle fiber length and therefore according to frank starling's law increased force of contraction
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Rings of Trauma: Hidden signs of Blunt trauma 1.Central Iris: Sphincter Tear 2.Peripheral Iris: Iridodialysis 3.Anterior Ciliary body: Angle recession 4.Separation of ciliary body from scleral spur: Cyclodialysis 5.Trabecular Meshwork: Trabecular Meshwork tear 6.Zonule/ lens: Zonular tear with possible lens subluxation...
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Lipid insoluble drugs do not enter cell. Ref-KDT 6/e p18
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Ans. is 'd' i.e., Malignant stricture of esophagus * Dysphagia for solids, with positive cervical lymph nodes with associated hoarseness of voice strongly points in the favour of an esophageal malignancy* Dysphagia equal for both solids and liquids from the very onset of disease suggests motor disorder like# Achalasia#...
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Ans. D i.e. None of the option Known complications of mumps include: Mumps viral infections in adolescent and adult males carry an up to 30% risk that the testes may become infected (orchitis or epididymitis), which can be quite painful; about half of these infections result in testicular atrophy, and in rare cases ste...
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ANS-A. Antipsychotic with Imipramine continuedThe condition from which the patient above is suffering is a bipolar disorder which includes both depression and mania. So in order to treat both antidepressant i.e imipramine is continued along with an antipsychotic such as phenothiazines, thioxanthenes, etc.Antipsychotic ...
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Ans. is 'a' i.e., Traction epiphysis Types of epiphysisExamplesPressureHead of femur, head of humerus, condyles of tibia, lower end of radiusTractionGreater and lesser trochanters of femur, tubercles of humerus, mastoid processAtavisticCoracoid process of scapula, posterior tubercle of talus (as trigonum)AberrantHead o...
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The most impoant layer of a slow sand filter is the vital layer or zoogleal layer or the biological layer. It is composed of thread like algae and other forms of life. It is called so because it removes organic matter, holds back bacteria and oxidises ammoniacal nitrogen and helps in yielding bacteria-free water. (PARK...
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(b) Atlanto-axial jointYes movement occurs at atlanto-occipital joint and No movement occurs at atlanto-axial joint.
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Ans. is 'b' i.e., .01% Leprosy is defined as public health problem w hen Prevalence rate is 1 or more per 10,000 population (.01%). "AN a result r the hard work and meticulously planned and executed activities. the country achieved the goal of elimination ty-lepros), as public health problem. defined as less than 1 COA...
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it includes hyperuricemia, hyperkalemia( pseudo), hyper phosphatemia and hypocalcemia( Harrison 17 pg 1736)
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Axillary dissection during modified radical mastectomy requires exposing the long thoracic and thoracodorsal nerves. Injury to the long thoracic nerve that supplies the serratus anterior muscle causes "winging of the scapula". The intercostobrachial nerve supplies sensory innervation to the skin in the axilla and proxi...
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Ans. is 'a' i.e., Coronary hea disease For non-communicable disease (e.g. CHD), primordial prevention is best intervention.
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Ans. is 'a' i.e., AFB + Macrophages o The bacilli are clumped together by a lipid - like substance, the glia, these masses are known as globi.o "In clinical material from lepromatous patient they (lepra) bacilli are typically found within the macrophages in dense clump " - Greenwood 16th/e p. 210Morphology of M. leprae...
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The symptom and the laboratory examination of the patients almost confirm the diagnosis of temporal arteritis. This question has been asked too frequently in various PGME examination you are required to be well versed with the differential diagnosis of a headache. Let's see the diagnostic features of various headaches....
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Ans. B. May show Hyperinflation of one lung field.The hallmark of an aspirated foreign body is a lung volume that does not change during the respiratory cycle. Due to the check valve mechanism, where air enters the bronchus around the foreign body but cannot exit, the affected lung will usually appear overinflated and ...
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Ans. is 'a' i.e., Asparginase o Asparaginase is a protein and it is an enzyme.# Asparaginase catalyzes the hydrolysis of asparagine to aspartic acid and ammonia.o Asparatrine is required for protein synthesis and is essential part of cellTumour cells, especially All cell, have low levels of aspargine synthetase, the en...
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Ref: R Alagappan - Manual of Practical Medicine 4th Edition.pg no:184 Cardiac Enzymes a. CPK-MB: This cardiac isoenzyme stas rising within 4-6 hrs after development of acute MI, peaks during the 2nd day (4 fold rise) and disappears in 2-3 days. Other causes of total CK elevation: 1. Skeletal diseases - Polymyositis, Mu...
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Ans: c (Dilated pupil)Ref: Harrison's, 16th ed, p 508,17th ed, p. 192Dilated pupil is not a feature of Homer syndrome. In Homer syndrome constricted pupil is seen.Horner syndromeHomer syndrome is due to involvement of sympathetic pathways to the eyes.Clinical featuresPtosisConstricted pupilEnophthalmosIpsilateral loss ...
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