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By 6 months, a child can begin to take a biscuit to his mouth. By 12 months, he can try to feed self with a cup but spills some of contents. By 15 months, he can drink from cup without much spilling By 18 months, he can feed himself well with a spoon
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HIV is RNA retrovirus (not DNA virus) • It primarily infect CD4+ T cells but can infect other cells also which bear CD4 receptor on their surface. These include circulating dendritic cells; epidermal langerhan’s cells; monocytes.
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Chronic Bronchitis The primary or initiating factor is exposure to noxious or irritating inhaled substances such as tobacco smoke (90% of patients are smokers) and dust from grain, cotton, and silica. Earliest feature is hypersecretion of mucus in the large airways, associated with hyperophy of the submucosal glands in...
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Ans. is 'a' i.e., Methotrexate o Folate antagonists which are used as anticancer cancer drugs :- (i) Methotrexate; (ii) Premetrexate
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Non pressure or mucostatic theory was given by Page, who wrote that, interfacial surface tension was the best way to retain dentures.
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Imatinib - first line drug for chronic phase CML,in blast crisis and second line therapy for chronic phase CML that has progressed on prior IFN-a therapy Imatinib is also first line drug for metastatic c-kit positive GIST. Nilotinib, Bosutinib, Dasatinib - used in treatment of resistant CML Dasatinib is also used for t...
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Ans. is 'b' i.e., 6 weeksIn myocardial infarction. Neutrophils appear at Granulation tissue appear at Beginning of fibrosis and organization of granulation tissue Development of fibrous scar (hearing)12-24 hrs. ---> 6 -10 days 7-14 days_____ > 2-6 weeks
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Ans. Neuroectoderm
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Ans. is 'd' i.e., All of the aboveMetacarpophalangeal joints o These are ellipsoid joints between head of metacarpals and base of proximal phalanx. Movement at MCP joints are flexion, extension, abduction and adduction.Movement Muscles producing movementsFlexion Main muscles :- The lumbricals and the interossei. Suppoi...
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Typically, the vaginal pH ranges between 4 and 4.5. It results from Lactobacillus species' production of lactic acid, fatty acids, and other organic acids. Other bacteria can also contribute organic acids from protein catabolism, and anaerobic bacteria contribute by amino acid fermentation. Stimulated by estrogens, the...
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Radiological features of scurvy: Palkan spur : metaphyseal spurs projecting at right angles to the shaft. White line of Frankel : calcified cailage in the metaphysis Trumefeld zone : zone of rarefraction below the white line of Frankel Wimburger sign : ring surrounding the ephiphyseal centres of ossification Pencil thi...
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Refer kDT 7/e p 565 Antihypeensives are a class of drugs that are used to treat hypeension (high blood pressure). Antihypeensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the ...
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Ans. D: Medullary carcinoma of thyroid MEN-1/Wermer syndrome is characterized by abnormalities involving the parathyroid, pancreas and pituitary gland; thus the mnemonic device, the 3P's. Parathyroid-Hyperparathyroidism is present in 80-95% of patients. Asymptomatic hypercalcemia is the most common manifestation: about...
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Among the supraglottic airway devise proseal has maximum seal Pressure thus has least chance of aspiration.
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Ans. is 'a' i.e., 2, 5 Gas Pin index Oxygen 2,5 Nitrous oxide 3,5 Cyclopropane 3, 6 Air 1, 5 Nitrogen 1, 4 Entonox (50% 02 + 50%N,0) Single central (7) Carbon dioxide (<7.5%) 2, 6 Carbon dioxide (> 7.5%) 1, 6
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A 35-year-old pregnant patient having:
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Pyeloplasty
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Ans. is 'c' i.e., BBT Miscellaneous methods of contraceptions These are (i) Abstinence, (ii) Coitus interruptus, (iii) Safe period (rhyth method), and (iv) Natural family planning methods. Abstinence There is complete abstinence from sexual intercourse. It is not used and can hardly be considered as a method of contrac...
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Presence of pain in the abdomen Bacillus cereus is an impoant cause of food poisoning Bacillus cereus causes two types of food borne illness. i) Sho incubation period or emetic form of the disease. ii) Long incubation period or diarrhoeal form of the disease.
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CLEIDOCRANIAL DYSPLASIA/DYSOSTOSIS (CCD)Autosomal recessive disease with faulty intramembranous bone ossificationLarge head with small face, abnormal dentition and drooping hypermobile shouldersRadiological features:Skulla. Platybasia b. Large foramen magnum c. Wormian bonesd. Persistent metopic suture e. 'Hot cross bu...
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- microbial laboratory culture wastes comes under category 3. - the category 3 wastes should be disposed in red colour plastic bag. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no :793,794 <\p>
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i.e. (N- acetyl cysteine): (680 - Ghai 7th)Overdosage of PCM is treated with N-acetyl cysteine used orally within 16 hour after ingestion at a loading dose of 140 mg/ Kg diluted to 5% solution orally. Followed by 70 mg /Kg q 4hr for another 2 daysPCM is the most common analgesic, antipyretic used in childrenParacetamol...
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Ans. C. E. colia. Urinary tract infections are more concerning in pregnancy due to the increased risk of kidney infections.b. During pregnancy, high progesterone levels elevate the risk of decreased muscle tone of the ureters and bladder, which leads to a greater likelihood of reflux, where urine flows back up the uret...
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Increased pCO2 indicates generation of protons in the body leading to acidosis Since increase in CO2 occurs due to respiratory pathology patient has respiratory acidosis For compensation HCO3 increases and but still pH is not normalised that means compensation is paial.
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Post - traumatic stress disorder occurs after on extreme traumatic events involving the threat of personal death or injury.
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Lactulose is a laxative that acts by conversion to sho chain fatty acids in the colon. These fatty acids resulrs in decrese in PH of intestinal juice. At low PH ammonia becomes ionized and thus cannot be absorbed.
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The preformed toxin of Staphylococcus causes nausea within 1-6 hours of ingestion. Ham, poultry, potato and egg salad, mayonnaise, and cream pastries are common food sources.
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Death rate declines still fuher and the bih rate tend to fall in third stage of demographic cycle or late expanding stage, but the population continue to grow as bihs exceeds death. India has entered this phase. Reference : Park&;s textbook of preventive and social medicine, 23rd edition, pg no: 479
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Ans: d (calcium pyrophosphate) Ref: Harrison 17th ed/p.2167.In Pseudogout, calcium pyrophosphate is depositedIn Gout, Monosodium urate crystal is depositedAssociations of CPPD (calcium pyrophosphate dihvdrate) crystal deposition:-* Ageing (most common)* Osteoarthritis* Familial* Metabolic diseases-HaemochromatosisHyper...
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Ans. Chloroquine
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Answer is A (High output due to diuretics): Presence of high urine osmolality >300 (316 mosmol/Kg) along with increased serum Na suggest a diagnosis of solute diuresis. The patient inquestion has sustained head injury and mannitol is often used insuch cases to reduce the intracranial pressure. Solute diuresis secondary...
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Ans. D: MALTomaMALTomas stand for mucosal associated lymphoid tissue.These are the extra-nodal equivalent of monocytoid (marginal zone) B-cell lymphomas occurring in lymphoid organs such as the lymph node.These lymphomas arise in numerous extranodal sites such as the stomach, salivary gland and thyroid, most of which l...
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(Multiple myeloma): (1041 -Davidson 21st edition)MULTIPLE MYELOMA - presents as multifocal destructive bone tumours composed of plasma cells throughout the skeletal system* The bone lesions appears radiographically as punched out defects usually 1-4 cm in diameter and grossly consists of gelatinous soft red tumour mass...
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Lymphatic drainage of glans penis is deep inguinal lymph nodes. Superficial inguinal lymph nodes- scrotum, perineum, vulva and anus Lymphatic drainage of testis is pre and para aoic lymph nodes.
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Treatment of grade IV VIJR Age 0-5 years Give antibiotic prophylaxis first Follow up the patient, if recurrences occur, surgical management should be done. Age 6-10 years Unilateral      -3 Same as above Bilateral     --> Surgery
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The Superficial Inguinal Lymph Nodes are found deep to Camper's fascia and Superficial to Fascia Lata. Femoral Triangle is a sub-fascial space (fascia lata being the roof), it contains only the Deep Inguinal Lymph Nodes Femoral triangle- Lateral border:medial border of saorius muscle Medial border: medial border of add...
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Ans. (a) 60 mmRef. DC Dutta 7th ed./ 41; William's Obstetrics 22nd ed./ 91* By the end of the 12th week of pregnancy, when the uterus usually is just palpable above thesymphysis pubis, the crown-rump length of the fetus is 6 to 7 cm i.e. 60 to 70 mm.* Please refer to above explanation for more details.
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The setting reaction takes time to complete and changes in the mixture begin as soon as the hemihydrate and water are mixed together.  X-ray diffraction data for set gypsum products indicate that there is less than 50% dihydrate present in Type IV and V stones, about 60% in Type II die materials, and over 90% in Type I...
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Ans. is 'b' i.e., LipochromeThe characteristic mentioned in the question are of lipochrome or lipofuscin. (See above explanation).
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Ans. is 'b' i.e., Secondarieso Secondaries are most common malignant bone tumor,o Osteogenic sarcoma is the most common primary malignant bone tumor,o Osteoma is most common benign bone tumor.
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Parasympathetic general visceral efferent out flow of vagus is through preganglionic fibers, as postganglionic neurons related to vagus are located in thoracic and abdominal autonomic plexus, close to or, within, the viscera supplied. It supplies Gastrointestinal tract from pharynx to the junction of the right 2/3rd an...
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Ariston pHc is a promising material for posterior restorations. We can recommend its use especially for the restoration of primary and young permanent teeth; this material does not require the acid-etching technique and thus the danger of dental pulp irritation by phosphoric acid is avoided. The application of Ariston ...
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Ans. is 'c' i.e., Descemet's membraneHistology of corneao The cornea has five distinct layers (from superficial to deep): -Epithelium : - It is the outermost part of cornea and is composed of stratified squamous non-keratinized epithelial cells.Bowman's membrane: - It is not a true membrane but simply a condensed super...
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In phacoemulsification, the nucleus is emulsified using high frequency sound waves and then sucked out of the eye through a small (3.2 mm) incision.
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C i.e. Tachycardia
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Ans. a. High frequency ventilation
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Ligamentum Venosum
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BOXING WAX AND BEADING WAX  USES  Used to build up vertical walls around the impression, in order to pour the stone and make a cast. The procedure is known as boxing.  SUPPLIED AS  Boxing wax as sheets, beading wax as strips. ADVANTAGES OF BEADING AND BOXING  Preserves the extensions and landmarks.  Controls the thick...
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Femoral artery branches -        Superficial Superficial external pudendal Superficial epigastric Superficial circumflex iliac -        Deep Profunda femoris Deep external pudendal Muscular branches Descending genicular branch
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Refer Robbins page no p922 Robbins 8th mentioned that paial lipodystrophy is adsoscated with C3 nephritic factor (C3NeF). It is associated with type 2 Membranoproliferative glomerulonephritis
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According to rule of Hasse, the age of fetus is 6 weeks. RULE OF HAASE It is a rough method of calculating the age of fetus. The length of fetus is measured from crown to heel in centimeters. During first five months of pregnancy- square root of length gives approximate age of fetus in months. During last five months- ...
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Abrus injection (sui needle) resembles viper snake bite. Ricinius communis produces diarrhea (cholera like action). Nux vomica contains strychnine, brucine and loganin.
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Ans. a. NeisseriaN. gonorrhoeae is Gram [?] diplococci.Metabolize glucose and produce IgA proteases.Contain lipooligosaccharides (LOS) with strong endotoxin activity.N gonorrhoeae is often intracellular (within neutrophils)GONOCOCCINo polysaccharide capsuleNo maltose metabolizedNo vaccine due to antigenic variation of ...
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Docusate is a stool-softening laxative that facilitates mixing of oil and water via its surfactant properties. Drugs that have muscarinic blocking effects, like scopolamine and the antihistamines diphenhydramine and promethazine, tend to cause constipation by decreasing GI motility. Loperamide is an opioid derivative, ...
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ICD ICD mentions International classification of mental and behavioural disorders this was given by WHO( World health Organisation) ICD is used all over the world except America latest edition of ICD is ICD11 ICD 11 was released in 2018 DSM DSM mentions Diagnostic and Statistical manual of mental disorders this was giv...
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In pregnancy, if the mother becomes infected during the first trimester, the incidence of transplacental infection is lowest (15%), but the disease in the neonate is most severe. If maternal infection occurs during the third trimester, the incidence of transplacental infection is greatest (65%), but the infant is usual...
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Ans. is 'b' i.e., Clonorchis sinensis Clonorchis sinensis is a trematode. It is also known as liver luke.Man is definitive host for Clonorchis and snail is the secondary host.Clonorchis sinensis is caused by ingestion of metacercaria in inadequately cooked freshwater fish.The organism's excyst in the duodenum.The larva...
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The branches of these divisions supply the pelvic viscera, the perineum, the pelvic walls, and the buttocks.Branches of the Anterior Division:Umbilical aery: From the proximal patent pa of the umbilical aery arises the superior vesical aery, which supplies the upper poion of the bladder.Uterine aery: It ends by followi...
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CRISPR - Cas9 involves both homologous and non homologous end joining repair mechanism.
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Although glucose 6-phosphate is common to both pathways, the pentose phosphate pathway is markedly different from glycolysis. Oxidation utilizes NADP rather than NAD, CO2, which is not produced in glycolysis, is a characteristic product No ATP is generated in the pentose phosphate pathway, whereas it is a major product...
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Ans. is 'c' i.e., Lapatinib
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Points to note Concentration of ions Na+ concentration higher in ECF K+ concentration higher in ICF Cl- concentration higher in ECF K+ leak channels allow K+ to move from ICF to ECF Na+ is prevented from entering the cell. Thus diffusion is highest for K+, then Cl- and least for Na+, when the cell is at rest.
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The drugs has been approved by FDA for the prophylactic management of migraine are propranolol,timolol,sodiumvalproate,topiramate,and methysergide *Other drugs appear to display prophylactic efficacy includes amitriptyline,noriptyline,flunarizine,phenelzine,gabapentin,topiramate,and cycloheptadine *Among these phenelzi...
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Ans. is cd' i.e., DNS o Cottle test: It is used to test nasal obstruction due to abnormality of nasal valve as in case of deviated nasal septum. o In this test, cheek is drawn laterally while the patient breathes quietly. If the nasal airway improves on the test side, the test is positive, and indicates abnormality of ...
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When maternal varicella occurs near delivery babies may develop congenital varicella within 2 weeks of delivery REF:ANANTHANARYANAN TEXTBOOK OF MICROBIOLOGY 9EDITION PGNO.472
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Ans. Three options are correct i.e., (b) i.e. Arises from periampullary region; (c) i.e. Jaundice & anaemia found
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The aiculations between the temporal bone (mandibular fossa) and the mandibular condyle form a synol joint, known as the temporomandibular joint (TMJ).A unique feature of the TMJ is the fibrocailaginous aicular disc, located within the joint capsule between the mandibular fossa and condyle.
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Ans. is 'c' i.e., Phenobarbitone
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Ans. (C). Mastoid region(Ref: Review of Forensic Medicine & toxicology; Gautum Biswas; 2nd edition; Pg - 236)Bruising/ecchymosis over the mastoid processQ in the line of posterior auricular artery.It is an indication of fracture of middle cranial fossaQof the skull, and may suggest underlying brain trauma
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Glutamine is the most abundant naturally occurring, non-essential amino acid in the human body and one of the only amino acids which directly crosses the blood-brain barrier.In the body it is found circulating in the blood as well as stored in the skeletal muscles. It becomes conditionally essential (requiring intake f...
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Ans. (b) Tall T waves in ECGRef: Harrison 19th ed. / 307,310* The earliest electrocardiogram (ECG) change associated with hypokalemia is a decrease in the T-wave amplitude.* As potassium levels decline further, ST-segment depression and T-wave inversions are seen, while the PR interval can be prolonged along with an in...
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Coical mastoidectomy, known as simple or complete mastoidectomy or Schwaz operation, is complete exenteration of all accessible mastoid air cells and conveing them into single cavity. Posterior meatal wall is left intact. Middle ear structures are not disturbed. Indications: 1. Acute coalescent mastoiditis 2. Incomplet...
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ANCA 2 types P-ANCA |aka MPO ANCA C-ANCA | aka PR3 ANCA Associated with - Churg strauss Syndrome Microscopic Polyangiitis Associated with - Wegner's Granulomatosis Polyaeritis Nodosa is example of ANCA negative vasculitis. Polyaeritis nodosa is Type III Hypersensitivity reaction. It is the example of fibrinoid necrosis...
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Characteristic vascular pathology of benign hypertension is hyaline arteriosclerosis. Vascular pathology in Hypertension Hypertension is associated with two forms of small blood vessels disease - 1. Hyaline arterioiosclerosis There is homogenous, pink, hyaline thickening of arteriolar wall. The lumen becomes narrow, o...
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Loperamide:- It is an opiate analogue with major peripheral u opioid and additional weak anti-cholinergic propey. As a constipating agent it is much more potent than codeine. Because of poor water solubility--little is absorbed from the intestines. Entry into brain is negligible--CNS effects are rare and occur only wit...
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Ans. (a) Microdochectomy(Ref. Bailey and Love 27th edition Page 865)Microdochectomy:* A lacrimal probe or a Stiff Nylon is used.* It is inserted into a single duct through which discharge is coming.* A tennis racket incision is made and the duct is excised.* Usually done for duct papilloma causing bloody discharge.* Ca...
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Ans. (d) Lipopolysaccharide Ref. Alum ilianarayan o/c, p 78, 'able (9.1), 9/e, p 75 Distinguishing features of exotoxins and endotoxins Proteins Heat labile Actively secreted by cells; diffuse into surrounding medium Readily separable from cultures by physical means such as filtration Action usually enzymic Specific ph...
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Ans. C: 294 days The normal duration of pregnancy is approximately 37 to 42 weeks, with the estimated due date at 40 weeks or 280 days from the first day of the last menstrual period. A postterm pregnancy/prolonged pregnancy/post maturity is one that has extended beyond 2 weeks of the expected date of delivery (beyond ...
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Buerger's disease is a progressive non-atherosclerotic segmental inflammatory disease that most often affects small and medium-sized aeries, veins, and nerves of the upper and lower extremities. Pathologically, thrombosis occurs in small to medium-sized aeries and veins with associated dense polymorphonuclear leukocyte...
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Ans. is 'c' i.e., > 20 sec o Apnea of prematurity defined as sudden stoppage of breathing that lasts for 20 sec or is associated with bradycardia or cyanosis.Apnea of prematurity should be differentiated from periodic breathing which is normal phenomenon is preterm neonate.
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A i.e. It is a condition of apparent death when no signs of life are discovered as the functions are interrupted for sometimes or are reduced to minimum
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Treatment of tuberculosis is not a contraindication for breast feeding. Breastfeeding should not be discouraged for women being treated with first-line anti-tuberculosis drugs because the concentrations of these drugs in breast milk are too small to produce toxicity in the nursing newborn. The child cannot be infected ...
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A i.e. Optic nerve and floor of orbit Agger nasi cells are medial relations of lacrimal sac & duct; Haller's cells develop medially beneath orbital floort2 and Sphenoethmoid or Onodi cells is intimately related to optic nerve & canal and internal carotid aeryQ. It may contain tuberculum nervi optic, where the optic can...
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Clinical Presentation of Phenylketonuria  The affected infant is normal at birth.  Profound intellectual disability develops gradually if the infant remains untreated.  Vomiting, sometimes severe enough to be misdiagnosed as pyloric stenosis.  Older untreated children become hyperactive with autistic behaviors includi...
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Complications of Acute renal failure - Hypotension, tachycardia Uremia Hyponatremia Hyperkalemia Metabolic acidosis Hyperphosphatemia Hypocalcemia Anemia, bleeding, DIC Cardiac complications -arrythmias, pericarditis,pericardial effusion. Ref:Harrison 20th edition pgno.2108
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Non specific esterase is negative in M3 type of Acute myeloid leukemia (AML). Alpha naphthyl acetate esterase (ANAE), Alpha naphthyl butyrate esterase (ANBE) and Alpha naphthyl AS esterase (NASA) are the non specific esterase reactions that are positive in M4 (acute myelomonocytic leukemia) and M5 (acute monocytic/mono...
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Ans. (c) Radical Mastectomy(Ref Internet Sources)Halstaed Radical mastectomy is historical.* It involves removal of Entire breast, Nipple and areola with tumor* Also removes all level 1,2,3 nodes* Muscles like Pectoralis major, Serratus Anterior are also removed.* It's a very high morbid procedure and hence not done no...
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Ans. 'a' i.e., Subepithelial deposits; 'b' i.e., Nephritis along with acute renal failure; `c' i.e., Low complement levelsPSGN appears 1 to 4 weeks after a streptococcal infection of pharynx or skin (impetigo).o Occurs most frequently in children 6 to 10 years of age, but adults any age can be affected.o The lesions ar...
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Robbins basic pathology. 6th edition. chapter 6 genetic disorders. page no.180 prader willi syndrome is characterised by mental retardation,sho stature,hypotonia,obesity,small hands and feet, and hypogonadism. so the answer ia option 4. In all cases deletions affects the paternally derived chromosome no.15.
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Modified biophysical score consists of NST or vibroacoustic non stress test and estimation of amniotic fluid volume using AFI. It takes 10 minutes to perform the score and is used as screening test. Ref: Williams Obs 24e pg 342-344.
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Ans. C i.e. Firearm injury Firearm wounds of skull In beveling the exit wound is bigger than the inlet wound There is internal beveling in the inlet and external beveling in the exit.
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Relapses are due to hypnozoites in liver. These are seen in case of P.vivax and P.ovale. P. Falciparum is not associated with relapses. P. falciparum infects RBC's of all ages, hence the parasitemia is very high. Hemoglobinuria is commonly seen.
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Antibody-mediated (type II) hypersensitivity disorders are caused by antibodies directed against target antigens on the surface of cells or other tissue components. The antigens may be normal molecules intrinsic to cell membranes or in the extracellular matrix, or they may be adsorbed exogenous antigens (e.g., a drug m...
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Syringomas are harmless eccrine sweat duct tumor(adenomas of intraepidermal eccrine ducts) Adenoma sebaceum - seen in tuberous sclerosis(nose involvement)
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AMOEBIC DYSENTERY. Causative agent: Entamoeba histolytica. Site of action: large intestine. Mode of transmission: Ingestion of cyst form of the parasite. Mechanism: The cyst wall is dissolved in the small intestine from where the liberated amoebae pass into the large intestine. they invade the epithelium of the mucosa,...
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Lateral rectus is supplied of by sixth nerve (abducent) nerve and superior oblique is supplied by fourth (trochlear) nerve. All other extraocular muscles are supplied by occulmotor nerve.
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Gestrinone has a long half life. It is a 19-noestosterone derivative. It is given orally 2.5 to 5 mg twice weekly for 6 to 9 months. It has androgenic, antiprogestagenic, antioestrogenic and antigonadotrophic action. Ref : Shaw's Textbook of Gynaecology
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High-resolution computed tomography is superior to the plain chest X-ray for early detection and confirmation of suspected ILD(interstitial lung disease).In addition,HRCT allows better assessment of the extent and distribution of disease,and it is especially useful in the investigation of patients with a normal chest r...
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Dating of pregnancy crown rump length is measured from the top of the head to the bottom of the buttocks excluding limbs CRL between 9 and 11 weeks is the most accurate method of dating CRL in cm + 6.5 gives a rough estimate of gestational age in weeks refer pgno:476 Sheila textbook of obstetrics 2 nd edition
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