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Initial diagnosis of PSS is through laboratory bloodwork showing either elevated serum bile acids after eating or elevation of fasting blood ammonia levels, which has been shown to have a higher sensitivity and specificity than the bile acids test. Various diagnostic imaging techniques are used to demonstrate PSS. Ultr...
https://en.wikipedia.org/wiki?curid=68595657
1,950,128
1,574,897
Research into both the azobenzene and norbonadiene-quadricyclane systems was abandoned in the 1980s as unpractical due to problems with degradation, instability, low energy density, and cost. With recent advances in computing power though, there has been renewed interest in finding materials for solar thermal fuels. In...
https://en.wikipedia.org/wiki?curid=3267910
1,574,008
1,973,551
An alternative theoretical tool to cope with strong fluctuations problems occurring in field theories has been provided in the late 1940s by the concept of renormalization, which has originally been devised to calculate functional integrals arising in quantum field theories (QFT's). In QFT's a standard approximation st...
https://en.wikipedia.org/wiki?curid=19668009
1,972,416
1,084,151
Space syntax originated as a programme research in the early 1970s when Bill Hillier, Adrian Leaman and Alan Beattie came together at the School of Environmental Studies at University College London (now part of the Bartlett School of Architecture). Bill Hillier had been appointed Director of the Unit for Architectural...
https://en.wikipedia.org/wiki?curid=174704
1,083,594
1,779,797
The contention surrounding the methodology that Saruhashi's team used was settled two years after the publication of her research concerning the artificial radioisotopes in seawater. The US Atomic Energy Commission funded a six-month long lab swap in which Saruhashi met with fellow oceanographer Ted Folsom at the Scrip...
https://en.wikipedia.org/wiki?curid=3998007
1,778,794
792,862
The last major improvement to the steam engine was the Corliss engine. Named after its inventor, George Henry Corliss, this stationary steam engine was introduced to the world in 1849. The engine boasted a number of desired features, including fuel efficiency (lowering cost of fuel by a third or more), low maintenance ...
https://en.wikipedia.org/wiki?curid=1424698
792,437
1,443,077
Finland is the country in which women were first permitted to undertake architectural studies and receive academic qualifications even if they were initially given the status of special students. The earliest record belongs to Signe Hornborg (1862–1916) who attended the Helsinki Polytechnic Institute from the spring of...
https://en.wikipedia.org/wiki?curid=35552352
1,442,264
1,651,119
Though the scope and dimensions of globalization as most people currently construe it are of fairly recent origin, the broader phenomenon of global interconnections through cultural diffusion and trade is several centuries old. Starting in the late Fifteenth century, European powers expanded beyond the European sub-con...
https://en.wikipedia.org/wiki?curid=17200325
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Transmission-based precautions remain in effect for limited periods of time (i.e., while the risk for transmission of the infectious agent persists or for the duration of the illness (Appendix A). For most infectious diseases, this duration reflects known patterns of persistence and shedding of infectious agents associ...
https://en.wikipedia.org/wiki?curid=30321101
1,274,970
293,004
Solar insolation is made up of direct, diffuse, and reflected radiation. The absorption factor of a PV cell is defined as the fraction of incident solar irradiance that is absorbed by the cell. At high noon on a cloudless day at the equator, the power of the sun is about 1 kW/m, on the Earth's surface, to a plane that ...
https://en.wikipedia.org/wiki?curid=15677755
292,846
1,240,630
The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases. These nonclassic eicosanoids are generally short-lived, being rapidly converted from epoxides to l...
https://en.wikipedia.org/wiki?curid=4367754
1,239,961
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The two main watercourses of Mesopotamia, which give the region its name, are the Euphrates and the Tigris, which flow from Anatolia to the Persian Gulf. The Euphrates is around 2,800 km long and the Tigris is about 1,900 km. Their regime is of the pluvial-naval type, with high flow in spring as a result of melting sno...
https://en.wikipedia.org/wiki?curid=59427724
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Some properties of Kottler-Møller or Rindler coordinates were anticipated by Albert Einstein (1907) when he discussed the uniformly accelerated reference frame. While introducing the concept of Born rigidity, Max Born (1909) recognized that the formulas for the worldline of hyperbolic motion can be reinterpreted as tra...
https://en.wikipedia.org/wiki?curid=54334250
1,776,300
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In 2004, professional horticulturist Robert Sacilotto wrote a summary of measured tolerances of highland "Nepenthes" species, based on experiments conducted between 1996 and 2001. Out of all of the studied species, "N. edwardsiana" proved to be the most challenging. Cotyledon-stage seedlings showed a 100% mortality rat...
https://en.wikipedia.org/wiki?curid=3834632
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Like most other large, ground-dwelling sloths, "Paramylodon" disappeared toward the end of the Pleistocene in the wake of the Quaternary extinction event. Unlike many other genera, however, there is little radiometric data available from "Paramylodon" measured directly from fossil material. Data. Among the most recent ...
https://en.wikipedia.org/wiki?curid=16886646
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It is becoming common in hemorrhaging patients "without" traumatic brain injury. Due to the lack of controlled clinical trials in this field, the growing evidence that hypotensive resuscitation results in improved long-term survival mainly stems from experimental studies in animals. Numerous animal models of uncontroll...
https://en.wikipedia.org/wiki?curid=30775715
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2,141,842
After receiving his M.D., Dr. Yan became the Chief Examiner at Coroner office of the Institute of Forensic Science of Liaoning Province, Shenyang, China. While he enjoyed his work as an Examiner and developed better techniques for DNA extraction from crime scene samples, but he soon became fascinated with the research ...
https://en.wikipedia.org/wiki?curid=56107542
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An older but still useful and practical method of determining accurate time at sea before the advent of precise timekeeping and satellite-based time systems is called "lunar distances", or "lunars", which was used extensively for a short period and refined for daily use on board ships in the 18th century. Use declined ...
https://en.wikipedia.org/wiki?curid=143335
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Acoustic information describing the environment is the primary data required in soundscape ecology studies. Technological advances have provided improved methods for the collection of such data. Automated recording systems allow for temporally replicated samples of soundscapes to be gathered with relative ease. Data co...
https://en.wikipedia.org/wiki?curid=31352483
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In "Why Most Public Research Findings are False" (2005), Ioannidis focused on why most published research findings cannot be validated. In a later paper on PLOS Medicine (2014), he discusses what can be done to improve this situation and make more published research findings to be true and in a third paper (2016) he sh...
https://en.wikipedia.org/wiki?curid=20900378
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Genome-wide association studies are general applications to find specific gene targets and polymorphisms within the human race. In fact, the International HapMap project was created through a partnership of scientists and agencies from several countries to catalog and utilize this data. The goal of this project is to c...
https://en.wikipedia.org/wiki?curid=4995479
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The institute has six centres of excellence (CoE), focusing on research and providing consultancy in particular technical fields. The CoE in Corrosion and Surface Engineering specializes in the field of corrosion and surface engineering. The centre offers MS and PhD programmes and has signed MoUs with government agenci...
https://en.wikipedia.org/wiki?curid=62648373
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In the United States, Minoru Yamasaki found major independent success in implementing unique engineering solutions to then-complicated problems, including the space that elevator shafts took up on each floor, and dealing with his personal fear of heights. During this period, he created a number of office buildings whic...
https://en.wikipedia.org/wiki?curid=315927
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In 1975, the Maharishi met with Pierre Trudeau to discuss "the possibility of structuring an ideal society" through TM. In 1977 a U.S. district court in New Jersey held that a curriculum comprising the Science of Creative Intelligence and TM was religious in nature ("Malnak v Yogi"). The decision was appealed and in 19...
https://en.wikipedia.org/wiki?curid=28677895
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There was growing interest in cultures and peoples in distant regions of the globe and photography was a way to place them under study especially when combined with influences from the study of phrenology and Darwin's work on natural selection. In 1850, Joseph T. Zealy (1812–93) was commissioned by Louis Agassiz to mak...
https://en.wikipedia.org/wiki?curid=33735616
1,384,624
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Monopulse radar was extremely "high tech" when it was first introduced by Robert M. Page in 1943 in a Naval Research Laboratory experiment. As a result, it was very expensive, labor-intensive due to complexity, and less reliable. It was only used when extreme accuracy was needed that justified the cost. Early uses incl...
https://en.wikipedia.org/wiki?curid=3924685
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Historian Immanuel C. Y. Hsu argues the movement was a superficial attempt to modernize limited areas of Chinese society. In striking contrast to the much more thorough modernization program at the same time in Japan, in China he says that there were no attempts to study or assimilate western institutions, philosophy o...
https://en.wikipedia.org/wiki?curid=407942
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In 1931, IBM produces the IBM 601 Multiplying Punch; it is an electromechanical machine that could read two numbers, up to 8 digits long, from a card and punch their product onto the same card. In 1934, Wallace Eckert used a rigged IBM 601 Multiplying Punch to automate the integration of differential equations. In 1936...
https://en.wikipedia.org/wiki?curid=6134187
536,015
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The MBL's contributions to neuroscience and sensory physiology are significant, fostered today by more than 65 visiting investigators and resident researchers in these fields, as well as five graduate- and post-graduate level Advanced Research Training courses. The MBL has been a magnet for the discipline since L.W. Wi...
https://en.wikipedia.org/wiki?curid=391313
1,144,993
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More significant than sheer numbers of scientific personnel were their quality and distribution. The total numbers masked wide variations in educational background and quality, lumping together graduates of two-year institutions or those who had attended secondary or post secondary schools during periods of low standar...
https://en.wikipedia.org/wiki?curid=14246598
1,792,205
1,120,860
Scholars do not agree that the Fremont culture represents a single, cohesive group with a common language, ancestry, or way of life, but several aspects of their material culture provides evidence for this concept. First, Fremont culture people foraged wild food sources and grew corn. The culture participated in a cont...
https://en.wikipedia.org/wiki?curid=1002184
1,120,286
1,808,730
Beerling is interested in the history of science and publishes occasional scholarly articles on this theme. These have included an invited commentary entitled 'Gas valves, forests and global change: a commentary on Paul Gordon Jarvis classic 1976 paper written to celebrate the 350th anniversary of the journal "Philosop...
https://en.wikipedia.org/wiki?curid=43094065
1,807,709
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Leaf Huang, Ph.D. is the Fred Eshelman Distinguished Professor, in the Eshelman School of Pharmacy, University of North Carolina at Chapel Hill. Dr. Huang’s research has been in the area of gene therapy and targeted drug delivery. He has pioneered the liposome non-viral vector and has designed and manufactured the cati...
https://en.wikipedia.org/wiki?curid=41428949
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In the United Kingdom another line of ceramic armour development had been started in the early 1960s, meant to improve the existing cast turret configuration of the Chieftain that already offered excellent heavy penetrator protection; the research by a team headed by Gilbert Harvey of the Fighting Vehicles Research and...
https://en.wikipedia.org/wiki?curid=200127
312,984
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The museum's Great Hall had the fossil reconstructions of various dinosaurs, including that of an Apatosaurus with an incorrect skull. However, the wall looked too empty for oceanographer and director of the Peabody Museum of Natural History (1938–1942), Albert Eide Parr. He wanted to make a series of small paintings o...
https://en.wikipedia.org/wiki?curid=8990816
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C measurements, even with low time resolution, can indicate the state of solar activity over the last 11,000 years until about 1900. Although radiocarbon dating has been applied as far back as 50,000 years, during the deglaciations at the start of the Holocene the biosphere and its carbon uptake changed dramatically ma...
https://en.wikipedia.org/wiki?curid=24728109
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In July 2015, Lockheed Martin confirmed the authenticity of a leaked report showing the F-35 to be less maneuverable than an older F-16D with wing tanks. The pilot who flew the mission reported inferior energy maneuverability, a limited pitch rate and flying qualities that were "not intuitive or favorable" in a major p...
https://en.wikipedia.org/wiki?curid=54719700
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"The Merck Manual" is organized, like many internal medicine textbooks, into organ systems (see List of Medical Topics below) which discuss each major diseases of that system, covering diagnosis (signs, symptoms, tests), prognosis and treatment. It provides a comprehensive yet concise compendium of medical knowledge in...
https://en.wikipedia.org/wiki?curid=1136647
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The purpose of this paper is to provide standardized definitions and a roadmap of test processes for the Environmental Stress Screening (ESS) of replacement and repaired components used on Air Force systems. The term “component” is used interchangeably with the term “unit” and includes Line-replaceable unit (LRU) and s...
https://en.wikipedia.org/wiki?curid=3115993
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A country’s innovative performance largely depends on how these actors relate to each other as elements of a collective system of knowledge creation and use as well as the technologies they use. For example, public research institutes, academia and industry serve as research producers carrying out research and developm...
https://en.wikipedia.org/wiki?curid=817238
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Treatment has historically centered on removing mechanical pressure from the joint until the disease has run its course. Options include traction (to separate the femur from the pelvis and reduce wear), braces (often for several months, with an average of 18 months) to restore range of motion, physiotherapy, and surgic...
https://en.wikipedia.org/wiki?curid=295047
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After 1929, with the Left Opposition legally banned and Trotsky exiled, Stalin led the Soviet Union into a what he termed a "higher stage of socialism." Agriculture was forcibly collectivised, at the cost of a massive famine and millions of deaths among the resistant peasantry. The surplus squeezed from the peasants wa...
https://en.wikipedia.org/wiki?curid=47246185
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On 25 May 2012 The North American Lake Management Society (NALMS), representing nearly 1,000 members-researchers, scientists, administrators, and citizens-wrote a letter of concern the imminent closure of ELA, arguing that NALMS' work "depends on findings from the ELA." NALMS asked the federal government to reconsider....
https://en.wikipedia.org/wiki?curid=28815488
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Electromagnetically induced transparency (EIT) was first introduced by Harris and his colleagues at Stanford University in 1990. The work showed that when a laser beam causes a quantum interference between the excitation paths, the optical response of the atomic medium is modified to eliminate absorption and refraction...
https://en.wikipedia.org/wiki?curid=60448457
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As artificial intelligence grows and the overwhelming amount of news portrayed through cyberspace expands, it is becoming extremely overwhelming for a voter to know what to believe. There are many intelligent codes, referred to as bots, written to portray people on social media with the goal of spreading misinformation...
https://en.wikipedia.org/wiki?curid=1164
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Computation-aided design has also been used to engineer complex properties of a highly ordered nano-protein assembly. A protein cage, E. coli bacterioferritin (EcBfr), which naturally shows structural instability and an incomplete self-assembly behavior by populating two oligomerization states, is the model protein in ...
https://en.wikipedia.org/wiki?curid=216104
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In 212 BC, the Emperor Qin Shi Huang commanded all books in the Qin Empire other than officially sanctioned ones be burned. This decree was not universally obeyed, but as a consequence of this order little is known about ancient Chinese mathematics before this date. After the book burning of 212 BC, the Han dynasty (20...
https://en.wikipedia.org/wiki?curid=14220
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Char syndrome is an autosomal dominant congenital disease caused by mutations in TFAP2B gene which affects the development of the bones of the face as well as the heart and limbs. During embryo development, TFAP2B regulates the production of the protein AP-2β, a transcription factor that is active in the neural crest a...
https://en.wikipedia.org/wiki?curid=60494555
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At the beginning of the 19th century Scottish universities had no entrance exam, students typically entered at ages of 15 or 16, attended for as little as two years, chose which lectures to attend and left without qualifications. After two commissions of enquiry in 1826 and 1876 and reforming acts of parliament in 1858...
https://en.wikipedia.org/wiki?curid=18943753
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However, exogenous irisin may aid in heightening energy expenditure, and thus in reducing obesity. Boström et al. reported on December 14, 2012: "Since the conservation of calories would likely provide an overall survival advantage for mammals, it appears paradoxical that exercise would stimulate the secretion of a pol...
https://en.wikipedia.org/wiki?curid=34368888
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Kh-101/102 is the latest development of the Kh-55, incorporating a low radar cross-section of about 0.01 square meters. The Kh-101/102 is specifically designed for air-launch, abandoning the circular fuselage cross-section of the Kh-55 for a nose and forward fuselage section aerodynamically shaped to produce lift. It i...
https://en.wikipedia.org/wiki?curid=1109032
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The ethics behind Mass Surveillance has become a highly discussed ethical topic in the twenty-first century, especially in the United States due to the tragedy of 9/11. Some areas of ethical concern involve privacy, discrimination, trust in government, infringement of government-granted rights/basic human rights, confl...
https://en.wikipedia.org/wiki?curid=699052
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The inside/outside discontinuity at the cell surface enabled by a lipid bilayer membrane (capacitor) is at the core of bioelectricity. The plasma membrane was an indispensable structure for the origin and evolution of life itself. It provided compartmentalization permitting the setting of a differential voltage/potenti...
https://en.wikipedia.org/wiki?curid=55498066
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Beginning in 1999 the Max Planck Society initiated the implementation of International Max Planck Research Schools (IMPRS) as a new way to cooperate with partner universities in Germany. The intention of this ambitious plan is twofold. On the one hand, the Max Planck Society tries to intensify the collaboration with un...
https://en.wikipedia.org/wiki?curid=6746982
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Located at 600 S. Michigan Avenue, Columbia College's Main Building was built in 1906–07 by Christian A. Eckstorm, an architect popular for his industrial and warehouse designs, to serve as the headquarters of the International Harvester Company. 600 S. Michigan was a modern skyscraper of its era, built with a steel sk...
https://en.wikipedia.org/wiki?curid=1914203
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Like related telescopes on Tenerife, it is a Cassegrain device with a thin primary mirror, around 2/3 thinner than in other contemporary devices and weighing only 6.5 tonnes. When trying to view distant objects in infra-red local sources of heat must be minimised, to this end a lighter mirror requires lower power motor...
https://en.wikipedia.org/wiki?curid=188198
1,533,023
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From a 2020 study published in Cell: "Understanding the nature of this movement was the primary motivation behind this study. Here, we present a large-scale analysis of genome-wide data from key sites of prehistoric Anatolia, the Northern Levant, and the Southern Caucasian lowlands ... In the Northern Levant, we identi...
https://en.wikipedia.org/wiki?curid=16696142
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Earth's rate of rotation must be integrated to obtain time, which is Earth's angular position (specifically, the orientation of the meridian of Greenwich relative to the fictitious mean sun). Integrating +1.7 ms/d/cy and centering the resulting parabola on the year 1820 yields (to a first approximation) seconds for Δ"T...
https://en.wikipedia.org/wiki?curid=8727
484,882
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The airship's skeleton was built of the new lightweight alloy duralumin 17-SRT. The frame introduced several novel features compared with traditional Zeppelin designs. Rather than being single-girder diamond trusses with radial wire bracing, the main rings of "Akron" were self-supporting deep frames: triangular Warren ...
https://en.wikipedia.org/wiki?curid=60944
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During most of the 20th century, obstetric fistulae were largely missing from the international global health agenda. This is reflected by the fact that the condition was not included as a topic at the landmark United Nations 1994 International Conference on Population and Development (ICPD). The 194-page report from t...
https://en.wikipedia.org/wiki?curid=231286
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Thomas Oatley has criticized OEP for an overemphasis on domestic political processes and for failing to consider the interplay between processes at the domestic level and macro processes at the global level: in essence, OEP scholarship suffers from omitted variable bias. According to Peter Katzenstein, Robert Keohane a...
https://en.wikipedia.org/wiki?curid=630327
927,170
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From the moment of its discovery, the cutaneous rabbit illusion piqued the curiosity of researchers, and many experiments investigating the effect have been conducted, most of them on the forearm. Studies have consistently shown that the rabbit illusion occurs only when successive taps are closely spaced in time; the i...
https://en.wikipedia.org/wiki?curid=9274813
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Brinster then collaborated with Richard Palmiter, a prominent molecular biologist at the University of Washington, to pioneer and develop the transfer of foreign genes into mammals, and they utilized these methods to elucidate the activity and function of many genes. Their seminal experiments catalyzed a worldwide revo...
https://en.wikipedia.org/wiki?curid=13365910
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1. (or retroductive) phase. Guessing, inference to explanatory hypotheses for selection of those best worth trying. From abduction, Peirce distinguishes induction as inferring, on the basis of tests, the proportion of truth in the hypothesis. Every inquiry, whether into ideas, brute facts, or norms and laws, arises fro...
https://en.wikipedia.org/wiki?curid=6117
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It was reported that 28 Iraqi Army Abrams had been damaged in fighting with militants, five of them suffering full armor penetration when hit by ATGMs, in the period between 1 January and the end of May 2014; some were destroyed or damaged by militants placing explosive charges on or in the vehicles, highlighting the l...
https://en.wikipedia.org/wiki?curid=25079265
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The intertidal zone and the photic zone in the oceans are relatively familiar habitat types. However the vast bulk of the ocean is inhospitable to air-breathing humans, with scuba divers limited to the upper or so. The lower limit for photosynthesis is and below that depth the prevailing conditions include total darkne...
https://en.wikipedia.org/wiki?curid=1596317
235,401
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The 'crucifix-fights' were about whether crucifixes could remain in state educational institutions after the separation of church and state at the end of the 19th century, and a provocative action in 1900 (a plaster crucifix was knocked down from a Holy Crown relief at the University of Budapest by unknown perpetrators...
https://en.wikipedia.org/wiki?curid=59180536
2,004,605
1,896,513
Perhaps Prain's most difficult time as Director of the Kew gardens was in the years 1904-1908 when he was one of the lead players in an industrial dispute which pitted him against his garden staff and the Kew Garden trade union. Surprisingly his chief adversary was his sub-foreman, William Purdom, representing a band o...
https://en.wikipedia.org/wiki?curid=6197607
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Ancient Greek philosophers, from Thales (fl. 550 BC) through even to the Roman period, developed an elaborate theory of what they termed the "psuchẽ" (psyche) (from which the first half of "psychology" is derived), as well as other "psychological" terms – "nous", "thumos", "logistikon", etc. Classical Greece (fifth cen...
https://en.wikipedia.org/wiki?curid=1573230
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CAL invented the first crash test dummy in 1948, the automotive seat belt in 1951, the first mobile field unit with Doppler weather radar for weather-tracking in 1956, the first accurate airborne simulation of another aircraft (the North American X-15) in 1960, the first successful demonstration of an automatic terrain...
https://en.wikipedia.org/wiki?curid=3601339
1,153,846
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""It is perfect from the terminus of the Great Western as far as" "Slough – that is, eighteen miles; the wires being in some places" "underground in tubes, and in others high up in the air, which last," "he says, is by far the best plan. We asked if the weather did not" "affect the wires, but he said not; a violent thu...
https://en.wikipedia.org/wiki?curid=79836
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The APG-77 radar has a low-observable, active-aperture, electronically scanned antenna with multiple target track-while-scan in all weather conditions; radar emissions can also be focused to overload enemy sensors as an electronic-attack capability. The radar changes frequencies more than 1,000 times per second to lowe...
https://en.wikipedia.org/wiki?curid=66299
2,637
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Early methods of secondary structure prediction, introduced in the 1960s and early 1970s, focused on identifying likely alpha helices and were based mainly on helix-coil transition models. Significantly more accurate predictions that included beta sheets were introduced in the 1970s and relied on statistical assessment...
https://en.wikipedia.org/wiki?curid=306769
837,029
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The Airacobra was one of the first production fighters to be conceived as a "weapons system"; in this case the aircraft (known originally as the Bell Model 4) was designed to provide a platform for the 37 mm T9 cannon. This weapon, which was designed in 1934 by the American Armament Corporation, a division of Oldsmobil...
https://en.wikipedia.org/wiki?curid=458867
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This third-class method is drastically different from the previous two algorithms listed. The most striking aspect is that it requires a different definition of what it means to be a void. Instead of the general notion that a void is a region of space with a low cosmic mean density; a hole in the distribution of galaxi...
https://en.wikipedia.org/wiki?curid=42644968
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Work on a long range 152 mm gun for Reserve of the Main Command units started in 1929, when the Bolshevik Plant in Saint Petersburg received from the Artillery Directorate requirements specifications for such a piece. The project received a factory index B-10. First barrel was manufactured in April 1932; it was sent fo...
https://en.wikipedia.org/wiki?curid=12364478
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The theory states that concentrating industries in specific regions creates several advantages. For one, greater economic activity occurs when many firms cluster in one area. In turn, this creates agglomeration spillovers which increases the total factor productivity of firms in the same county since they are all compe...
https://en.wikipedia.org/wiki?curid=24693249
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Some researchers have suggested that dopamine systems in the mesolimbic pathway may contribute to the 'positive symptoms' of schizophrenia, whereas problems concerning dopamine function within the mesocortical pathway may be responsible for the 'negative symptoms', such as avolition and alogia. Abnormal expression, thu...
https://en.wikipedia.org/wiki?curid=599614
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In 1995, Square's "Chrono Trigger" raised the standards for the genre, with certain aspects that were considered revolutionary in its time, including its nonlinear gameplay, branching plot, the "Active Time Event Logic" system, more than a dozen different endings, plot-related sidequests, a unique battle system with in...
https://en.wikipedia.org/wiki?curid=32408675
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The mathematical notions of trusted systems for the protection of classified information derive from two independent but interrelated corpora of work. In 1974, David Bell and Leonard LaPadula of MITRE, under the technical guidance and financial sponsorship of Maj. Roger Schell, Ph.D., of the U.S. Army Electronic System...
https://en.wikipedia.org/wiki?curid=55888
1,258,114
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Fancisco J. Duarte (Maracaibo 1883 – Caracas 1972) Engineer and mathematician. He obtained in 1900, the title of bachelor and surveyor in Puerto Cabello. In 1902 with only 19 old he dedicated to study of mathematics, doing a work on the sign π up to 200 decimal digits, presented to the Academy of Sciences of Paris in 1...
https://en.wikipedia.org/wiki?curid=29302481
1,515,947
446,357
In 1972 Alvin Weinberg, co-inventor of the light water reactor design (the most common nuclear reactors today) was fired from his job at Oak Ridge National Laboratory by the Nixon administration, "at least in part" over his raising of concerns about the safety and wisdom of ever larger scaling-up of his design, especia...
https://en.wikipedia.org/wiki?curid=36030827
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Individuals can develop short-term tolerance with careful physical preparation and systematic monitoring of movements, but the biological changes are quite temporary and reversible when they return to lowlands. Moreover, unlike lowland people who only experience increased breathing for a few days after entering high al...
https://en.wikipedia.org/wiki?curid=39127332
550,940
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The Office of Security used LSD in interrogations, but Sidney Gottlieb, the chemist who directed MKUltra, had other ideas: he thought it could be used in covert operations. Since its effects were temporary, he believed it could be given to high-ranking officials and in this way affect the course of important meetings, ...
https://en.wikipedia.org/wiki?curid=42043
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Alpha synuclein, having no single, well-defined tertiary structure, is an intrinsically disordered protein, with a pI value of 4.7, which, under certain pathological conditions, can misfold in a way that exposes its core hydrophobic residues to the intracellular milieu, thus providing the opportunity for hydrophobic in...
https://en.wikipedia.org/wiki?curid=507325
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The second phase involves improved nutrition as a result of stable food production along with advances in medicine and the development of health care systems. Mortality in Western Europe and North America was halved during the 19th century due to closed sewage systems and clean water provided by public utilities, with ...
https://en.wikipedia.org/wiki?curid=4639874
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X-linked agammaglobulinemia (XLA) is a rare genetic disorder discovered in 1952 that affects the body's ability to fight infection. As the form of agammaglobulinemia that is X-linked, it is much more common in males. In people with XLA, the white blood cell formation process does not generate mature B cells, which mani...
https://en.wikipedia.org/wiki?curid=2507689
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After studying photos for NASA's Apollo program that contained greater detail than any ground-based telescope, Gerard Kuiper began seeking an arid site for infrared studies. While he first began looking in Chile, he also made the decision to perform tests in the Hawaiian Islands. Tests on Maui's Haleakalā were promisin...
https://en.wikipedia.org/wiki?curid=267376
836,522
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In September 2011, 19 soldiers participated in a two-week assessment of the LSAT light machine gun at Fort Benning, Georgia to demonstrate its capabilities against the M249 SAW. In one test the soldiers, half armed with SAWs and half with LSATs, marched six miles in full combat gear then fired at targets to measure str...
https://en.wikipedia.org/wiki?curid=18864541
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Siddiqi was born in Rawalpindi, Pakistan, and is a direct descendant of the well-known leader of the Khilafat Movement, Muslim activist, journalist and poet, Maulana Mohammad Ali Jauhar (Urdu: مَولانا مُحمّد علی جَوہر) Siddiqi moved to New York City at an early age. He attended the Bronx High School of Science, Bronx, ...
https://en.wikipedia.org/wiki?curid=52731536
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Geography can also affect economic development in a number of ways. Analysis of current data sets show three significant implications of geography on developing nations. First, access to sea routes is important; this has been noted as far back as Adam Smith. Sea travel is much cheaper and faster than that of land, lead...
https://en.wikipedia.org/wiki?curid=2149045
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Prior to the late 1800s treatments consisted of reconstruction and repair by craftsmen, familiar with the object materials and corrosion was thought to be a type of bacteria. In the late 1800s, scientists began looking into understanding the causes of deterioration and corrosion. In 1888: Flinders Petrie (1853-1942) pu...
https://en.wikipedia.org/wiki?curid=31121305
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The scientists were quick to realize the merits of photography because of its perceived ability to present an objective image of what was seen. This solved a problem of representation by artists who were asked to produce illustrations only from description or highly influenced by the interpretation of physicians and su...
https://en.wikipedia.org/wiki?curid=33735616
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Thalamotomy can be performed in an invasive or noninvasive manner. If performed invasively, then prior to the operation, a neurosurgeon uses stereotactic technology to identify the exact part of the brain that needs treatment by putting in place a frame on the patient’s head with four pins to keep it still. The doctor ...
https://en.wikipedia.org/wiki?curid=1874888
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"Mycoplasma alligatoris" was first isolated in a study led by D. R. Brown of six captive alligators showing signs of pneumonia, polyserositis (inflammation of serous membranes), and multifocal arthritis. The isolates were obtained from various organs, blood, synovial fluid, and cerebrospinal fluid and subject to variou...
https://en.wikipedia.org/wiki?curid=46500140
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Understanding the importance of getting runners on base, Beane focussed on acquiring players with a high on base percentage with the logic that teams with a higher on base percentage are more likely to score runs. He was also able to achieve success on a shoestring budget by acquiring overlooked starting pitchers, ofte...
https://en.wikipedia.org/wiki?curid=51589225
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In August 2005, the San Jose Water Company submitted a proposal to log a 1000-acre swathe of redwood trees in the Los Gatos Mountains, and sent copies to Moore and her neighbors. Moore started a subgroup of her civic association, Neighbors Against Irresponsible Logging, to oppose the project, and used the Google Earth ...
https://en.wikipedia.org/wiki?curid=50587818
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The position of the Roman Catholic Church on the theory of evolution has changed over the last two centuries from a large period of no official mention, to a statement of neutrality in the early-1950s, to limited guarded acceptance in recent years, rejecting the materialistic and reductionist philosophies behind it, an...
https://en.wikipedia.org/wiki?curid=39709452
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Coelacanths are a part of the clade Sarcopterygii, or the lobe-finned fishes. Externally, several characteristics distinguish coelacanths from other lobe-finned fish. They possess a three-lobed caudal fin, also called a trilobate fin or a diphycercal tail. A secondary tail extending past the primary tail separates the ...
https://en.wikipedia.org/wiki?curid=45503
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HAK5 is linked to disease prevention because if there is a lack of K or nutrients within a plant or cell, bacterial growth is promoted. K is important for the generation of PAMPs (pathogen-associated molecular patterns) recognition, which is involved in the innate immune system for living cells. PAMPs are the main mole...
https://en.wikipedia.org/wiki?curid=54988028
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