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Above approximately 900 °C a typical low-carbon steel is composed entirely of austenite, a high-temperature phase of iron that has a cubic close-packed crystal structure. On cooling, it tends to transform into a mixture of phases, ferrite and cementite, depending on the exact chemical composition. A steel of eutectoid composition will under equilibrium conditions transform into pearlite – an interleaved mixture of ferrite and cementite (FeC). In addition to the thermodynamic considerations indicated by the phase diagram, the phase transformations in steel are heavily influenced by the chemical kinetics. This is because the diffusion of iron atoms becomes difficult below about 600 °C under typical processing conditions. As a consequence, a complex array of microstructures occurs when the atomic mobility is limited. This leads to the complexity of steel microstructures which are strongly influenced by the cooling rate. This can be illustrated by a continuous cooling transformation (CCT) diagram which plots the time required to form a phase when a sample is cooled at a specific rate thus showing regions in time-temperature space from which the expected phase fractions can be deduced for a given thermal cycle.
https://en.wikipedia.org/wiki?curid=288452
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Aplacophorans are worm-like animals, with little resemblance to most other molluscs. They have no shell, although small calcified spicules are embedded in the skin; these spicules are occasionally coated with an organic pellicle that is presumably secreted by microvilli. Caudofoveates lack a foot while solenogasters have a narrow foot which lacks intrinsic musculature. The mantle cavity is reduced into a simple cloaca, into which the anus and excretory organs empty, and is located at the posterior of the animal. The head is rudimentary, and has no eyes or tentacles. The cuticle of both subclasses is chitinous, and has an irregular texture. Spines bear an organic matrix. Sclerites can be hollow or solid; the void within the sclerites of some species fills during growth. Sclerites generally form within the cuticle, protruding through when they are fully grown. They probably start life as amorphous calcium carbonate, which the organic matrix coaxes into an aragonitic habit as the spines mature. Sclerites can be shaped as simple spines, straight, curved, keeled, striated or hooked; or as cupped blades; more complex arrangements are common in copulatory spicules. In several species of solenogaster, sclerites change morphology during growth; young specimens might bear flat, solid, scale-like sclerites, to be replaced with longer hollow spine-like sclerites in adults.
https://en.wikipedia.org/wiki?curid=2025047
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Any person who is found to have cryptococcosis at a site outside of the central nervous system (e.g., pulmonary cryptococcosis), a lumbar puncture is indicated to evaluate the cerebrospinal fluid (CSF) for evidence of cryptococcal meningitis, even if they do not have signs or symptoms of CNS disease. Detection of cryptococcal antigen (capsular material) by culture of CSF, sputum and urine provides definitive diagnosis. Blood cultures may be positive in heavy infections. India ink of the CSF is a traditional microscopic method of diagnosis, although the sensitivity is poor in early infection, and may miss 15–20% of patients with culture-positive cryptococcal meningitis. Unusual morphological forms are rarely seen. Cryptococcal antigen from cerebrospinal fluid is the best test for diagnosis of cryptococcal meningitis in terms of sensitivity. Apart from conventional methods of detection like direct microscopy and culture, rapid diagnostic methods to detect cryptococcal antigen by latex agglutination test, lateral flow immunochromatographic assay (LFA), or enzyme immunoassay (EIA). A new cryptococcal antigen LFA was FDA approved in July 2011. Polymerase chain reaction (PCR) has been used on tissue specimens.
https://en.wikipedia.org/wiki?curid=743429
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It is a generally held belief within the acupuncture community that acupuncture points and meridians structures are special conduits for electrical signals, but no research has established any consistent anatomical structure or function for either acupuncture points or meridians. Human tests to determine whether electrical continuity was significantly different near meridians than other places in the body have been inconclusive. Scientific research has not supported the existence of "qi", meridians, or yin and yang. A "Nature" editorial described TCM as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action. Quackwatch states that "TCM theory and practice are not based upon the body of knowledge related to health, disease, and health care that has been widely accepted by the scientific community. TCM practitioners disagree among themselves about how to diagnose patients and which treatments should go with which diagnoses. Even if they could agree, the TCM theories are so nebulous that no amount of scientific study will enable TCM to offer rational care." Academic discussions of acupuncture still make reference to pseudoscientific concepts such as "qi" and meridians despite the lack of scientific evidence.
https://en.wikipedia.org/wiki?curid=1537
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Electric eels reproduce during the dry season, from September to December. During this time, male-female pairs are seen in small pools left behind after water levels drop. The male makes a nest using his saliva and the female deposits around 1,200 eggs for fertilisation. Spawn hatch seven days later and mothers keep depositing eggs periodically throughout the breeding season, making them fractional spawners. When they reach , the hatched larvae consume any leftover eggs, and after they reach they begin to eat other foods. Electric eels are sexually dimorphic, males becoming reproductively active at in length and growing larger than females; females start to reproduce at a body length of around . The adults provide prolonged parental care lasting four months. "E. electricus" and "E. voltai", the two upland species which live in fast-flowing rivers, appear to make less use of parental care. The male provides protection for both the young and the nest. Captive specimens have sometimes lived for over 20 years.
https://en.wikipedia.org/wiki?curid=61262925
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These approaches employ the same probabilistic framework as used to infer the phylogenetic tree. In brief, the evolution of a genetic sequence is modelled by a time-reversible continuous time Markov process. In the simplest of these, all characters undergo independent state transitions (such as nucleotide substitutions) at a constant rate over time. This basic model is frequently extended to allow different rates on each branch of the tree. In reality, mutation rates may also vary over time (due, for example, to environmental changes); this can be modelled by allowing the rate parameters to evolve along the tree, at the expense of having an increased number of parameters. A model defines transition probabilities from states "i" to "j" along a branch of length "t" (in units of evolutionary time). The likelihood of a phylogeny is computed from a nested sum of transition probabilities that corresponds to the hierarchical structure of the proposed tree. At each node, the likelihood of its descendants is summed over all possible ancestral character states at that node:
https://en.wikipedia.org/wiki?curid=6383817
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Mutational analysis of entire gene families revealed that genes of the same family have similar functions, as predicted by similar coding sequences and protein domains. Two such classes are the kinase family, involved in adding phosphate groups to proteins and the phosphatase family, involved with removing phosphate groups from proteins. These families were first examined because of their apparent role in transducing cellular signals of cell growth or death. In particular, more than 50% of colorectal cancers carry a mutation in a kinase or phosphatase gene. Phosphatidylinositold 3-kinases (PIK3CA) gene encodes for lipid kinases that commonly contain mutations in colorectal, breast, gastric, lung and various other cancers. Drug therapies can inhibit PIK3CA. Another example is the BRAF gene, one of the first to be implicated in melanomas. BRAF encodes a serine/threonine kinase that is involved in the RAS-RAF-MAPK growth signaling pathway. Mutations in BRAF cause constitutive phosphorylation and activity in 59% of melanomas. Before BRAF, the genetic mechanism of melanoma development was unknown and therefore prognosis for patients was poor.
https://en.wikipedia.org/wiki?curid=7737653
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As with other myopathies, the clinical manifestations of MTM/CNM are most notably muscle weakness and associated disabilities. Congenital forms often present with neonatal low muscle tone, severe weakness, delayed developmental milestones (particularly gross motor milestones such as head control, crawling, and walking) and pulmonary complications (presumably due to weakness of the muscles responsible for respiration). Involvement of the facial muscles may cause ophthalmoplegia or ptosis. A mutation in the RYR1 gene causing CNM may also cause susceptibility to malignant hyperthermia, a potentially life-threatening reaction to anesthesia. While some patients with centronuclear myopathies remain ambulatory throughout their adult life, others may never crawl or walk and may require wheelchair use for mobility. There is substantial variability in the degree of functional impairment among the various centronuclear myopathies. Although this condition only affects the voluntary muscles, several children have had cardiac arrest, possibly due to the additional stress placed on the heart.
https://en.wikipedia.org/wiki?curid=4960443
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The tubes often appear to form colonies, although they are sometimes found in more isolated situations. The frequent appearance of large and sometimes single-species colonies has been attributed to the lack of significant predation. On the other hand, in some locations up to 20% of "Cloudina" fossils contain predatory borings ranging from 15 to 400 μm in diameter. The boreholes are rather evenly distributed along the tube length, and some tubes had been bored multiple times—hence the organism could survive attacks, since predators do not attack empty shells. This may indicate that the animal could vary its position in the tube in response to predation, or that it occupied the full length—but not the full width—of the tube. The even distribution is perhaps difficult to reconcile with an infaunal lifestyle, mainly buried in a microbial mat, and adds weight to Miller's suggestion that the animal lived on seaweeds or in a reef environment. If modern-day molluscs are a suitable analogy, the size distribution of the borings suggests that the predator was similar in size to "Cloudina".
https://en.wikipedia.org/wiki?curid=43174
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The engine has a single overhead camshaft driven by a timing belt. The Slant-4 was one of three engines using this method of driving the camshaft released the same year, the others being the Fiat Twin Cam engine and the Pontiac straight-6 OHC. Prior to 1966, belt-driven camshafts had only appeared in the Glas 1004 series starting in 1962 and in the few Devin-Panhard cars built starting in 1956. The camshaft operated two valves per cylinder. An ingenious valve train design incorporating an inclined socket head cap screw allowed valve clearances to be adjusted with a feeler gauge and an Allen key. The block and crossflow head are both of cast iron. The layout lowers the overall height of the engine, which allowed for more aerodynamic vehicle bodies to be achieved by lowering the bonnet line. It also means most of the engine is very easy to access for maintenance, with the exception of the exhaust manifold and spark plugs, which are "underneath" the slanted cylinders.
https://en.wikipedia.org/wiki?curid=232240
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A central structural argument explaining the high activity of metal oxide supported gold clusters is based on the concept of periphery sites formed at the junction between the gold cluster and the substrate. In the case of CO oxidation, it has been hypothesized that CO adsorbs onto the edges and corners of the gold clusters, while the activation of oxygen occurs at the peripheral sites. The high activity of edge and corner sites towards adsorption can be understood by considering the high coordinative unsaturation of these atoms in comparison with terrace atoms. The low degree of coordination increases the surface energy of corner and edge sites, hence making them more active towards binding adsorbates. This is further coupled with the local shift of the d-band center of the unsaturated Au atoms towards energies closer to the Fermi level, which in accordance with the d-band model results in increased substrate-adsorbate interaction and lowering of the adsorption-dissociation energy barriers. Lopez "et al." calculated the adsorption energy of CO and O on the Au(111) terrace on which the Au-atoms have a coordination number of 9 as well as on an Au cluster where the most reactive sites have a coordination of 4. They observed that the bond strengths are in general increased by as much as 1 eV, indicating a significant activation towards CO oxidation if one assumes that the activation barriers of surface reactions scale linearly with the adsorption energies (Brønsted-Evans-Polanyi principle). The observation that hemispherical two-layer gold clusters with a diameter of a few nanometers are most active for CO oxidation is well in line with the assumption that edge and corner atoms serve as the active sites, since for clusters of this shape and size the ratio of edge atoms to the total number of atoms is indeed maximized.
https://en.wikipedia.org/wiki?curid=57084837
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Mercedes began the season with a one–two finish in Australia, resulting in a twenty-eight-point lead after just one round. They finished over thirty seconds clear of Sebastian Vettel, who finished third and secured a podium finish in his first race with Ferrari. Red Bull's Daniel Ricciardo finished a lap down in sixth, prompting the team to continue to voice their frustrations with Renault, as they were forced to use its second of four allotted power units for Ricciardo on the very first day of the season. The team also voiced its displeasure over the progress Renault had made in terms of power, with the team principal, Christian Horner, saying the Renault Energy F1-2015 was still down on Mercedes's PU106B Hybrid. After the race, the Red Bull team advisor Helmut Marko suggested that Red Bull might exit Formula One entirely if changes to the regulations were not made to level the field or cut development costs. Renault countered with their own threat to pull out of Formula One as an engine supplier if its reputation continued to be damaged or if its participation was otherwise not profitable to the company. Mercedes followed up by finishing second and third in Malaysia, while Red Bull continued to struggle, rounding out the top ten a lap down. After four rounds, Mercedes led the field, having earned 159 points (with Lewis Hamilton acquiring 93 out of 100 possible points), while Red Bull's struggles continued. The team acquired twenty-six points, enough for a distant fourth, and Ricciardo entered the European stages of the season on his fourth and final permissible power unit with fifteen events remaining on the calendar.
https://en.wikipedia.org/wiki?curid=39263987
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During World War I he served with a "Landwehr" regiment on the Western Front, and with the chemical warfare unit headed by Fritz Haber on the Western, Eastern and Italian fronts, earning the Iron Cross (2nd Class) for his part in the First Battle of Ypres. After the war he became the head of the Kaiser Wilhelm Institute for Chemistry, while remaining in charge of his own department. Between 1934 and 1938, he worked with Strassmann and Meitner on the study of isotopes created through the neutron bombardment of uranium and thorium, which led to the discovery of nuclear fission. He was an opponent of national socialism and the persecution of Jews by the Nazi Party that caused the removal of many of his colleagues, including Meitner, who was forced to flee Germany in 1938. During World War II, he worked on the German nuclear weapons program, cataloguing the fission products of uranium. As a consequence, at the end of the war he was arrested by the Allied forces; he was incarcerated in Farm Hall with nine other German scientists, from July 1945 to January 1946.
https://en.wikipedia.org/wiki?curid=46825
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The Better Place network was the first modern commercial deployment of the battery swapping model. The Renault Fluence Z.E. was the first mass production electric car enable with switchable battery technology and sold for the Better Place network in Israel and Denmark. Better Place launched its first battery-swapping station in Israel, in Kiryat Ekron, near Rehovot in March 2011. The battery exchange process took five minutes. , there were 17 battery switch stations fully operational in Denmark enabling customers to drive anywhere across the country in an electric car. By late 2012 the company began to suffer financial difficulties, and decided to put on hold the roll out in Australia and reduce its non-core activities in North America, as the company decided to concentrate its resources on its two existing markets. On 26 May 2013, Better Place filed for bankruptcy in Israel. The company's financial difficulties were caused by the high investment required to develop the charging and swapping infrastructure, about million in private capital, and a market penetration significantly lower than originally predicted by Shai Agassi. Less than 1,000 Fluence Z.E. cars were deployed in Israel and around 400 units in Denmark.
https://en.wikipedia.org/wiki?curid=951197
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Thomas's work was not fully appreciated in his own lifetime. Only during the First World War did his techniques come to be used for injured soldiers on the battlefield. His nephew, Sir Robert Jones, had already made great advances in orthopedics in his position as surgeon-superintendent for the construction of the Manchester Ship Canal in 1888. He was responsible for the injured among the 20,000 workers, and he organized the first comprehensive accident service in the world, dividing the 36-mile site into three sections, and establishing a hospital and a string of first-aid posts in each section. He had the medical personnel trained in fracture management. He personally managed 3,000 cases and performed 300 operations in his own hospital. This position enabled him to learn new techniques and improve the standard of fracture management. Physicians from around the world came to Jones' clinic to learn his techniques. Along with Alfred Tubby, Jones founded the British Orthopedic Society in 1894.
https://en.wikipedia.org/wiki?curid=430380
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Arterial and venous disease treatment by angiography, stenting, and non-operative varicose vein treatment sclerotherapy, endovenous laser treatment are rapidly replacing major surgery in many first world countries. These newer procedures provide reasonable outcomes that are comparable to surgery with the advantage of short hospital stay (day or overnight for most cases) with lower morbidity and mortality rates. Historically performed by interventional radiologists, vascular surgeons have become increasingly proficient with endovascular methods. The durability of endovascular arterial procedures is generally good, especially when viewed in the context of their common clinical usage i.e. arterial disease occurring in elderly patients and usually associated with concurrent significant patient comorbidities especially ischemic heart disease. The cost savings from shorter hospital stays and less morbidity are considerable but are somewhat balanced by the high cost of imaging equipment, construction and staffing of dedicated procedural suites, and of the implant devices themselves.
https://en.wikipedia.org/wiki?curid=585708
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His distinctive contribution to reading and dyslexia research was to show that John Marshall's 'two route model of reading' could explain the dyslexias in both alphabetic and logographic orthographies such as Chinese and Japanese. According to the two-route model, the reader simultaneously processes words as a whole and the components of words—letters in alphabetic scripts, and radicals in Chinese. Reading fluency depends on whether the outcomes of these two processes are compatible. In English, they often are not: -INT is pronounced one way in MINT and another way in PINT. This incompatibility slows down reading that word. He showed that this applies also to Chinese, as he showed with his student, Yin Wengang and Japanese with colleague Taeko Wydell. He also showed that each route could be separately impaired in development—developmental dyslexia—and in brain damage—acquired dyslexia—again in both alphabetic and logographic scripts. To learn an alphabetic script, it is critical to learn how each letter is pronounced—this is sometimes called 'phonics'—but of course orthographies such as English there are many exceptions that just need to be learned. For example, the letter C is pronounced differently in COT, MICE, AND CHURCH. He showed that the phonic route could be selectively impaired or spared in both learners and neurological patients. In development, learners who are unable to parse a whole syllable into their component phonemes will have great difficulty learning to read, and will have to rely on recognizing words as a whole, as he was the first to show. This would not be a problem for learning to read Japanese, and he reported a young man of English-speaking parents, raised in Japan, severely dyslexic in English but a superior reader of Japanese. His siblings were fluent readers in both languages.
https://en.wikipedia.org/wiki?curid=22614234
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Davies was born on 13 July 1814 at Holywell, Flintshire. His father was Thomas Davies and his mother was Elizabeth Turner. He studied botany and in 1843 began work at the Geology Department of the British Museum, first also in the field of mineralogy, later specialising in vertebrate palaeontology. On 1 April 1846 he joint the Survey as a Fossil Collector. Davies assisted Sir Antonio Brady in his work on collecting Pleistocene mammal fossils, and Brady acknowledged his debt to Davies in "Catalogue of Pleistocene Mammalia from Ilford, Essex" (1874). Excavating a large mammoth skull, Davies used the innovation of surrounding the fossil, in the field, with plaster of Paris, reinforced by iron bars. In 1874 he salvaged the "Dacentrurus" holotype. Davies was awarded the inaugural Murchison Medal from the Geological Society of London in 1873, and was made a fellow (FGS) in 1877. In 1875, he was made an Assistant, responsible for the entire fossil collection of the museum, and in 1880 was promoted Assistant First Class. In 1880, Davies supervised the transfer of the museum's collections to new buildings in the Natural History Museum.
https://en.wikipedia.org/wiki?curid=40354895
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Xu Xing, another Chinese paleontologist, named a new species of "Psittacosaurus" in 1997, based on a complete skull with associated vertebrae and a forelimb. This material was recovered in Gansu Province, near the border with Inner Mongolia. This species is named "P. mazongshanensis" after the nearby mountain called Mazongshan (Horse Mane Mountain) and has been described in a preliminary manner. Unfortunately, the skull was damaged while in the care of the Chinese Institute of Vertebrate Paleontology and Paleoanthropology (IVPP), and several fragments have been lost, including all of the teeth. The remains were found in the Lower Xinminbao Formation, which have not been precisely dated, although there is some evidence that they were deposited in the late Barremian through Aptian stages. Sereno suggested in 2000 that "P. mazongshanensis" was a "nomen dubium", with no unique features that separate it from any other species of "Psittacosaurus". However, more recent authors have noted that it can be distinguished by its proportionally long snout compared to other species of "Psittacosaurus", as well as a prominent bony protuberance, pointing outwards and downwards, on the maxilla of the upper jaw. The maxillary protuberance is also now missing. Other features originally used to distinguish the species have been recognised as the results of the deformation of the skull after fossilisation. Sereno (2010) remained unconvinced of its validity.
https://en.wikipedia.org/wiki?curid=2274247
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Johnson's design, named CL-282, was based on the Lockheed XF-104 with long, slender wings and a shortened fuselage. The design was powered by the General Electric J73 engine and took off from a special cart and landed on its belly. It could reach an altitude of and had a radius. The reconnaissance aircraft was essentially a jet-powered glider. In June 1954, the USAF rejected the design in favor of the Bell X-16 and the modified B-57. Reasons included the lack of landing gear, use of the J73 engine instead of the more proven Pratt & Whitney J57 used by the competing designs, and not using multiple engines, which the USAF believed to be more reliable. General Curtis LeMay of Strategic Air Command (SAC) walked out during a CL-282 presentation, saying that he was not interested in an airplane without wheels or guns.
https://en.wikipedia.org/wiki?curid=32310
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In order to successfully establish a Dutch chemical association, it was first of all necessary to find out whether a sufficient number of members could be counted on. Following the medical yearbook for the Netherlands published since 1882, the two friends published a chemical yearbook in 1898 that contained an address list of Dutch chemists at home and abroad. The editors consisted of Jorissen, Rutten, the Amsterdam pharmacist and chemist Bernardus Adrianus van Ketel (1862-1928), H.C. Prinsen Geerligs (born 1864), director of the sugar cane testing station in Kagok, Tegal (Java), and Dr. Lodewijk Theodorus Reicher (1857-1943), chemical mechanic at the Municipal Health Service in Amsterdam and chief of the associated chemical laboratory. The second volume appeared in 1901; the third in 1902. The editorial board was expanded with Dr. Albert Jacques Joseph van de Velde (1871-1956), director of the city laboratory in Ghent. The title therefore became: "Scheikundig Jaarboekje voor Nederland, België en Nederlands Indië" (English: Chemical Yearbook for the Netherlands, Belgium and the Dutch East Indies). In the meantime, the Journal of Applied Chemistry and Hygiene was founded in 1897 of which Jorissen became co-editor. The chemical yearbook and the journal would play a major role in the founding of the Dutch Chemical Association.
https://en.wikipedia.org/wiki?curid=18044630
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CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) have also been developed. These systems can precisely alter gene transcription at the DNA level without inflicting irreversible genetic alterations. Furthermore, by directly acting on DNA they are generally more specific and predictable compared to RNAi. Although CRISPRi/a cannot replace genome editing in all experiments, they can act as effective alternatives in some cases. CRISPRi and CRISPRa use a deactivated Cas9 (dCas9) enzyme that cannot cut DNA, but can deliver transcriptional activators and repressors to modulate desired gene expression with high precision. Currently, off-target effects of CRISPRi are minimal, and show a reduced response and sensitivity to single-base mismatches. Importantly, when non-specific effects do inevitably occur they are reversible, time-dependent, and less damaging than DNA editing, making them effective alternatives that can limit the off-target burden when possible. CRISPR-cas13b, using a type IV CRISPR-Cas system (as opposed to the commonly used type II) can target and edit specific RNA sequences. Such an RNA editing platform has the ability to specifically edit mRNA, and therefore protein translation, without altering the DNA. The represents a promising technology that if successful would reduce the burden of irreversible off-target mutations.
https://en.wikipedia.org/wiki?curid=56710049
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While in college, Fawcett illustrated a book on athletic bandaging that had been written by the football team's physician. This may have been his only contribution as an illustrator; his later and more widely popular books were illustrated by Sylvia Collard Keen. In the summers, Fawcett worked on Bailey Island off the coast of Maine, where he embalmed and prepared small sharks for sale to colleges for comparative anatomy courses. This early interest in anatomy served him well when he trained in surgery at Harvard. Fawcett's predominant memory of his clinical training was being on duty in the emergency ward the night of the infamous Cocoanut Grove Nightclub disaster of 1942, which claimed 492 lives in one of the deadliest fires in American history. "We had been having a quiet evening when, without advance notice, we received 115 seriously burned patients within an hour and a half. Mobilizing all of the off-duty staff that I could reach, I continued on duty for 30 hours doing all I could to relieve the pain and dress the burns of the victims." He received his M.D. in 1942.
https://en.wikipedia.org/wiki?curid=27794457
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The smaller scale German nuclear program likewise tried to acquire uranium, putting the Berlin based Auergesellschaft, which had been taken from previous Jewish-German owners, in charge of acquisition. A substantial amount of uranium from the Belgian Congo (and thus the same source as the one used by the Americans) fell into German hands when the Wehrmacht conquered Belgium. Another important source was mining in the Ore Mountains (mostly on the Czech side, which had been annexed after the Munich treaty of 1938). While incompetence, bad luck, lack of resources and infighting kept the Germans from ever assembling enough uranium and neutron moderator in a single "pile" to achieve criticality, by the end of the war more than enough uranium had been in German hands to theoretically allow for the construction of a crude reactor on the scale of Chicago Pile-1 or the Soviet F-1 (nuclear reactor) if it had all been assembled in a single place. The Haigerloch research reactor () assembled months before the end of the war in Southwestern Germany was an extremely subcritical assembly which lacked both sufficient uranium and sufficient moderator to produce significant amounts of plutonium, let alone heat. A uranium cube thought to have belonged to Werner Heisenberg was analyzed decades later, confirming that the Germans were nowhere near plutonium production.
https://en.wikipedia.org/wiki?curid=4913827
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JiTT can make a difference in student study skills. Students in Marrs' biology class credit JiTT to a significant decrease in cramming for tests. She asked her students "Did you put off studying for Biotech 540 and as a result 'cram' for Biotech 540 tests?" to her graduate students, and 34% answered yes. However, 62% of the class answered in affirmative to the question "Do you 'cram' for other courses that you have this semester?" Gavrin reported that 80% of the students in his JiTT class responded "yes" to "Do the JiTT exercises help you to be well prepared for lecture?" versus 21% affirmative to the same question in "other classes". He found a 58% vs. 18% split on "staying focused", a 59% vs. 18% split on "feeling like an active participant", and a 71% vs. 21% split on "finding classroom time useful". When trying to assess the efficacy of any pedagogical strategy, it is important to appreciate that the choice and implementation of a particular teaching method will affect student and faculty attitudes and motivation as well as learning outcomes. In her use of JiTT at Penn State Brandywine, Laura Guertin has noticed strongly positive reactions from her students:
https://en.wikipedia.org/wiki?curid=33453274
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The oxygen sensors for most rebreathers are calibrated at the surface before the dive using air or 100% oxygen at normal atmospheric pressure. These are reliable calibration points but the range of operational partial pressures may extend beyond these calibration points, and if the sensors are calibrated for a linear response between these conditions and the response is extrapolated, for setpoints above 1 bar, which is standard practice, the control system must operate outside of the range for which restonse is known to be linear. One of the most common modes of failure is for a cell to become current-limited as it ages. The internal impedance changes as the anode is consumed by the reaction which produces the output current, and the response becomes non-linear at higher oxygen partial pressures. The signal may indicate a lower partial pressure and does not increase proportionately as oxygen is added, leading to a loop oxygen partial pressure that may increase to dangerous levels without warning. A way of validating the sensors at high partial pressures is to expose the sensor to higher PO than the upper setpoint by exposing it to pure oxygen at a depth of 6 m, for a PO of 1.6 bar during the dive, or at 1.6 bar or more in a calibration pressure pot. Both these methods are cumbersome and the in-water method may cause spiking of the PO during descent. A variation of the ASV system using oxygen, called a hyperoxic linearity test (HLT), uses oxygen as the flushing gas at 6 m, which can check that the sensor is linear to 1.6 bar PO, and if it fails, the set point can be automatically reduced to within the linear range established during calibration. A single sensor with PSV and ASV has been shown to be more reliable than three sensors with conventional voting logic. The effectiveness of cell validation algorithms is expected to improve with the acquisition of more field data gathered by the rebreather control systems.
https://en.wikipedia.org/wiki?curid=62138749
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The microglial sensome is a relatively new biological concept that appears to be playing a large role in neurodevelopment and neurodegeneration. The sensome refers to the unique grouping of protein transcripts used for sensing ligands and microbes. In other words, the sensome represents the genes required for the proteins used to sense molecules within the body. The sensome can be analyzed with a variety of methods including qPCR, RNA-seq, microarray analysis, and direct RNA sequencing. Genes included in the sensome code for receptors and transmembrane proteins on the plasma membrane that are more highly expressed in microglia compared to neurons. It does not include secreted proteins or transmembrane proteins specific to membrane bound organelles, such as the nucleus, mitochondria, and endoplasmic reticulum. The plurality of identified sensome genes code for pattern recognition receptors, however, there are a large variety of included genes. Microglial share a similar sensome to other macrophages, however they contain 22 unique genes, 16 of which are used for interaction with endogenous ligands. These differences create a unique microglial biomarker that includes over 40 genes including P2ry12 and HEXB. DAP12 (TYROBP) appears to play an important role in sensome protein interaction, acting as a signalling adaptor and a regulatory protein.
https://en.wikipedia.org/wiki?curid=1552187
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On 14 October 1947, the American-owned Boeing 314 flying boat "Bermuda Sky Queen", carrying sixty-nine passengers was flying from Foynes, Ireland to Gander, Newfoundland. Gale-force winds had slowed her progress and she was running low on fuel. Too far from Newfoundland and unable to make it back to Ireland, the captain, Charles Martin, twenty-six-year-old ex-Navy pilot, decided to fly toward which was on Ocean Station Charlie in the North Atlantic. The plane's captain decided to ditch and have his passengers and crew picked up by "Bibb". In 30-foot (10 m) seas, the transfer was both difficult and dangerous. Initially the "Bibb's" captain, Capt. Paul B. Cronk, tried to pass a line to the plane which taxied to the lee side of the cutter. A collision with the cutter ended this attempt to save the passengers. With worsening weather, a fifteen-man rubber raft and a small boat were deployed from the ship. The raft was guided to the escape door of the aircraft. Passengers jumped into the raft which was then pulled to the boat. After rescuing 47 of the passengers, worsening conditions and the approach of darkness forced the rescue's suspension. By dawn, improved weather allowed the rescue to resume and the remaining passengers and crew were transferred to the "Bibb". The rescue made headlines throughout the country and upon their arrival in Boston, "Bibb" and her crew received a hero's welcome for having saved all those aboard the ditched "Bermuda Sky Queen".
https://en.wikipedia.org/wiki?curid=6204230
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Thanks to an unbeaten season and sitting inside the Top 12 teams in the final BCS survey, the Boise State University Broncos, champions of the Western Athletic Conference, earned their way into the BCS for a visit to the Tostitos Fiesta Bowl. They defeated the Big 12 champions, the University of Oklahoma Sooners, at the new University of Phoenix Stadium in Glendale, Arizona on New Year's Day. Many sports journalists hailed the game as an "instant classic" for its dramatic ending. Oklahoma scored 25 straight points in the second half to rally from an 18-point deficit and take the lead; the teams combined to score 22 points in the final 90 seconds. The Broncos used three successful trick plays to get to overtime then win the game: a hook and lateral play on 4th-and-18 to score the tying touchdown with seven seconds left, a halfback option pass for an overtime touchdown on 4th-and-2, and a Statue of Liberty play on a two-point conversion attempt to win the game. Not only did Boise State win, but they also claimed a fourth win for the BCS non-AQ conferences in seven games against BCS AQ conferences.
https://en.wikipedia.org/wiki?curid=5754477
1,797,158
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New synthetic methodologies are constantly required in the pharmaceutical sector due to the increasing diversity of chemical modalities used to treat human disease. The rate of exploration of new chemical space has significantly increased over the last few decades, which increases the complexity of the chemical structures being pursued. This continuing evolution represents a consistent challenge to pharmaceutical chemists and demands new bond forming processes. The structural complexity of a molecule is often linked to the complexity of its synthesis, features which can be combined and measured by determining the molecule’s current complexity. In this context, developing commercially viable, efficient and sustainable synthetic routes to these compounds requires both innovation in strategy and capability. To address these challenges, chemists in the pharmaceutical sector have applied the concept of disruptive innovation, innovation that delivers a step change in the efficiency of preparing a molecule, in their approach to route development. Thus, the discovery, development, and rapid application of new synthetic methodologies, such as the reductive Heck reaction, can significantly enhance chemists’ capability to prepare novel drug candidates.
https://en.wikipedia.org/wiki?curid=60828102
1,524,275
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Don Lash and Louis Zamperini dead-heated in the 5000 meters; originally, Lash was ruled to be the sole winner, but after photo-finish review the result was changed to a tie. Lash (who had already qualified in the 10,000 meters) was the early leader, but slowed down to support his Indiana teammate Tom Deckard. When Deckard's place in the top three was clear, Lash resumed running his own race, battling with Zamperini for victory. In the 3000-meter steeplechase Harold Manning broke Volmari Iso-Hollo's world best of 9:09.4; second-time Olympians Joe McCluskey and Glen Dawson took the next spots. The warm weather, with temperatures of up to , was not conducive to fast distance running; Manning noted he had worked in even hotter conditions and could handle the heat. As the steeplechase did not become an official world record event until 1954, Manning's time was only ratified as a national record.
https://en.wikipedia.org/wiki?curid=48496607
1,990,244
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'Engineer' is the annual technical symposium at NITK Surathkal. 'ENGI' as it is called by the students has the Penrose Triangle as its logo, and this theme has been used along with the tag-line, 'Think. Create. Engineer.' ‘Engineer’ in its first edition in 2005 was born out of the amalgamation of three smaller scale technical symposia held until then. Engineer 2006 was planned on a larger scale, with innovative events including paper presentations, Shrishti, where participants are required to apply engineering for the greater good of society, robotics events (Perfect Machine, Automata), hacking contests, programming contests, electronics design events, and workshops. Socially conscious engineering has been a recurring theme. Guest speakers at Video conferences include Richard Stallman, Bjarne Stroustrup, Sam Pitroda, Dr. Devi Shetty, Sir Anthony James Leggett, Kevin Warwick, and Tim Poston. Engineer 2010 was dubbed the 'Golden Edition' due to it coinciding with the Golden Jubilee year celebrations. NITK hosted its first TEDx conference during Engineer 2011, and many influential speakers of the region were invited to talk on socially relevant issues. From the year 2018, Engineer has also hosted its annual NITK Model United Nations conference where the committees focus on various pressing issues around the globe and have a committee which focuses on the theme of the fest.
https://en.wikipedia.org/wiki?curid=1090003
891,163
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The shamanism hypothesis of schizophrenia states that in traditional societies the experience of psychosis facilitated the induction of shamans (magico-religious practitioners such as medicine men, diviners, witch doctors, exorcists and mediums). Shamanism is a common feature of human societies, with certain individuals deemed to have a particular connection to the supernatural world which gives them the ability to perform magic, especially healing. This in particular is used explain the common religious and grandiose content of psychotic experiences and the belief in supernatural powers, which may have been believed rather than disbelieved in traditional societies. The onset of schizophrenia also closely resembles shamanic initiations, which often feature hallucinations, delusions and incoherent speech. Possible links between shamanism and insanity have been recognised for many decades by anthropologists (e.g. "...mentally ill people are often regarded as holy in primitive societies" and "Feeblemindedness is treated with scorn in Niue today, but insanity still calls forth respect" ) but the most recent iteration of the theory is by Joseph Polimeni, who argues that shamans facilitate group functioning, and so psychosis evolved as a result of group selection. Critics have argued that the trance states and self-control exhibited by shamans are unlike the characteristics of schizophrenia.
https://en.wikipedia.org/wiki?curid=42449890
1,148,236
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In 1961, he married Valerie Joy Prowse, with whom he had one son and two daughters. Prior to embarking on his academic career at the University of Western Australia (UWA) in 1969, he had worked as a press and radio journalist for four years and gained eight years' experience of teaching in primary, secondary and senior technical education. At UWA, he became an associate professor in political science "with a particular focus on twentieth century totalitarianism and was best known publicly for his involvement in two high-profile campaigns, as a leading critic of the Western Australian Burke Labor government ... and as a vocal direct-election republican". After his death, UWA established a Patrick O'Brien Foundation "in honour of his outstanding contribution to issues of public policy and political debate in Australia" with funds donated by colleagues, friends and admirers.
https://en.wikipedia.org/wiki?curid=31228260
2,169,592
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Eusocial insects also serve as valuable tools in studying cheating. Eusocial insects behave cooperatively, where members of the community forgo reproduction to assist a few individuals to reproduce. Such model systems have potential for conflict of interest to arise among individuals, and thus also have potential for cheating to occur. Eusocial insects in the order Hymenoptera, which includes bees and wasps, exhibit good examples of conflicts of interest present in insect societies. In these systems, queen bees and wasps can mate and lay fertilized eggs that hatch into females. On the other hand, workers of most species in Hymenoptera can produce eggs, but cannot produce fertilized eggs due to loss of mating ability. Workers that lay eggs represent a cost for the colony because workers that lay eggs often do significantly less work, and thus negatively impact the health of the colony (for example: decreased amount of collected food, or less attention given to tending the queen's eggs). In this case, a conflict of interest arises between the workers and the colony. The workers should lay eggs in order to pass on their genes; however, as a colony, having only the queen reproduce leads to better productivity. If workers sought to pass their own genes by laying eggs, foraging activities would diminish, leading to decreased resources for the entire colony. This, in turn, can cause a tragedy of the commons, where selfish behavior lead to the depletion of resources, with long-term negative consequences for the group. However, in natural bee and wasp societies, only 0.01–0.1% and 1%, respectively, of the workers lay eggs, suggesting that strategies exist to combat cheating to prevent tragedy of the commons. These insect systems have given scientists opportunities to study strategies that keep cheating in check. Such strategies are commonly referred to as "policing" strategies, generally where additional costs are imposed on cheaters to discourage or eliminate cheating behaviors. For example, honeybees and wasps may eat eggs produced by workers. In some ant species and yellowjackets, policing may occur via aggression towards or killing egg-laying individuals to minimize cheating.
https://en.wikipedia.org/wiki?curid=5467149
1,352,383
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On December 31, 2021, the ground team at the Space Telescope Science Institute in Baltimore, Maryland began the deployment of the two telescoping "mid-booms" from the left and right sides of the observatory, pulling the five sunshield membranes out of their folded stowage in the fore and aft pallets, which were lowered three days earlier. Deployment of the left side boom (in relation to pointing direction of the main mirror) was delayed when mission control did not initially receive confirmation that the sunshield cover had fully rolled up. After looking at extra data for confirmation, the team proceeded to extend the booms. The left side deployed in 3 hours and 19 minutes; the right side took 3 hours and 42 minutes. With that step, Webb's sunshield resembled its complete, kite-shaped form and extended to its full 47-foot width. Commands to separate and tension the membranes were to follow.
https://en.wikipedia.org/wiki?curid=52495051
493,657
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The schools went into further decline starting from the Southern Song period (1127–1279) after the loss of the north to the Jin dynasty. The government was reluctant to fund them because they did not create immediate profits and as a result, cuts were made in teaching personnel, and the national university itself was reduced in size. The exception to this was in the 1140s when the court played an active role in reconstructing schools and made efforts to staff them with degree-holders. After this period, government involvement in state educational institutions ceased. According to contemporary complaints about the schools, they deteriorated in quality, were subjected to a variety of abuses and heterodox teaching, no teaching at all, and decline in revenue. Schools in imperial China never recovered from the decline starting from the Southern Song. For the rest of China's dynastic history, government funded academies functioned primarily as gateways to the examination system, and did not offer any real instruction to students. Functionally they were not schools but rather preparatory institutions for the examinations. Wang's goal of replacing the examinations was never realized. Although Wang's reforms fell short of their mark, they launched the first state led initiative to regulate the day to day education of its subjects through the appointment of teachers and funding of schools.
https://en.wikipedia.org/wiki?curid=244479
285,249
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One of the greatest challenges involved with constructing quantum computers is controlling or removing quantum decoherence. This usually means isolating the system from its environment as interactions with the external world cause the system to decohere. However, other sources of decoherence also exist. Examples include the quantum gates, and the lattice vibrations and background thermonuclear spin of the physical system used to implement the qubits. Decoherence is irreversible, as it is effectively non-unitary, and is usually something that should be highly controlled, if not avoided. Decoherence times for candidate systems in particular, the transverse relaxation time "T" (for NMR and MRI technology, also called the "dephasing time"), typically range between nanoseconds and seconds at low temperature. Currently, some quantum computers require their qubits to be cooled to 20 millikelvin (usually using a dilution refrigerator) in order to prevent significant decoherence. A 2020 study argues that ionizing radiation such as cosmic rays can nevertheless cause certain systems to decohere within milliseconds.
https://en.wikipedia.org/wiki?curid=25220
18,805
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Primary familial brain calcification (see Fahr's syndrome) is a rare disease involving bilateral calcifications in the brain, predominantly in basal ganglia but also cerebellum, thalamus, and brainstem in patients presenting with diverse neurologic (e.g. movement disorders, parkinsonism, seizures, headache) features and psychiatric (e.g. cognitive impairment, mood disorders, psychotic symptoms, and obsessive-compulsive) disturbances. In a minority of cases, the disease is associated with apparent autosomal dominant loss of function mutations in "PDGFRB" or the gene which encodes a ligand that simulates PDGFRB, Platelet-derived growth factor, "PDGFB". PDGFRB is extensively expressed in the neurons, chorioid plexus, vascular smooth muscle cells, and pericytes of the human brain, particularly the basal ganglia and the dentate nucleus. It is proposed that signal transduction through PDGFRB maintains blood–brain barrier integrity and that loss of the PDGFRB receptor or its ligand, PDGFB, disrupts the blood–brain barrier, subsequently promoting (peri)vascular calcium deposition and thereby causing the dysfunction and death of neurons.
https://en.wikipedia.org/wiki?curid=14076099
1,251,037
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In March 1970, the U.S. recommended that all NATO forces adopt the 5.56×45 mm cartridge. This shift represented a change in the philosophy of the military's long-held position about caliber size. By the mid 1970s, other armies were looking at M16-style weapons. A NATO standardization effort soon started and tests of various rounds were carried out starting in 1977. The U.S. offered the 5.56×45 mm M193 round, but there were concerns about its penetration in the face of the wider introduction of body armor. In the end the Belgian 5.56×45 mm SS109 round was chosen (STANAG 4172) in October 1980. The SS109 round was based on the U.S. cartridge but included a new stronger, heavier, 62 grain bullet design, with better long range performance and improved penetration (specifically, to consistently penetrate the side of a steel helmet at 600 meters). Due to its design and lower muzzle velocity (about 3110 ft/s) the Belgian SS109 round is considered more humane because it is less likely to fragment than the U.S. M193 round. The NATO 5.56×45 mm standard ammunition produced for U.S. forces is designated M855.
https://en.wikipedia.org/wiki?curid=19901
10,882
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Artemisinin is a Chinese herb (qinghaosu) that has been used in the treatment of fevers for over 1,000 years, thus predating the use of Quinine in the western world. It is derived from the plant "Artemisia annua", with the first documentation as a successful therapeutic agent in the treatment of malaria is in 340 AD by Ge Hong in his book "Zhou Hou Bei Ji Fang" ("A Handbook of Prescriptions for Emergencies"). Ge Hong extracted the artemesinin using a simple macerate, and this method is still in use today. The active compound was isolated first in 1971 and named artemisinin. It is a sesquiterpene lactone with a chemically rare peroxide bridge linkage. It is thought to be responsible for the majority of its anti-malarial action, although the target within the parasite remains controversial. At present it is strictly controlled under WHO guidelines as it has proven to be effective against all forms of multi-drug resistant "P. falciparum", thus every care is taken to ensure compliance and adherence together with other behaviors associated with the development of resistance. It is also only given in combination with other anti-malarials.
https://en.wikipedia.org/wiki?curid=186625
862,762
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Compared to other green algae species, Botryococcus braunii has a relatively thick cell wall that is accumulated from previous cellular divisions; making extraction of cytoplasmic components rather difficult. Much of the useful hydrocarbon oil is outside of the cell, acting as a biofilm to aggregate individual cells into colonies. The best method of separating the oils from the cells with minimal damage to the cells has long been sought. For some time, it has been known that hexane can perform this function. However, an electrical method may be cleaner and better overall. Electric fields have been applied in short pulses to extract hydrocarbons from other species of microalgae by weakening the cell walls. These pulses have been microseconds to milliseconds in length. In April 2017 it was reported researchers at Kumamoto University in Japan have used shorter, nanosecond long pulses to target the extracellular matrix of Botryococcus braunii. They found the electric method to be less costly and less damaging to the cells than other methods. The Kunamoto scientists found that when the pulses are applied ten times per second, the optimal field strength was 50 kilovolts per centimeter and the optimal energy applied to be 55.6 Joules per milliliter of Botryococcus braunii matrix. Polysaccharides are also extracted from the matrix and must be separated from the oils.
https://en.wikipedia.org/wiki?curid=7794987
1,317,634
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Biomaterials can be derived either from nature or synthesized in the laboratory using a variety of chemical approaches utilizing metallic components, polymers, ceramics or composite materials. They are often used and/or adapted for a medical application, and thus comprise the whole or part of a living structure or biomedical device which performs, augments, or replaces a natural function. Such functions may be relatively passive, like being used for a heart valve, or maybe bioactive with a more interactive functionality such as hydroxy-apatite coated hip implants. Biomaterials are also used every day in dental applications, surgery, and drug delivery. For example, a construct with impregnated pharmaceutical products can be placed into the body, which permits the prolonged release of a drug over an extended period of time. A biomaterial may also be an autograft, allograft or xenograft used as a transplant material.
https://en.wikipedia.org/wiki?curid=6259941
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Otto von Guericke's first diplomatic mission on behalf of the city led him in September 1642 to the court of the Elector of Saxony at Dresden. Von Guericke's mandate was to bring about a more lenient treatment from the Saxon military commander for Magdeburg. In 1648 he represented the city at the peace treaty delegation, that ended the Thirty Year's War. During a 1654 diplomatic mission to Regensburg, Guericke presented his invention of the air-pump to impress those he was going to meet and help sway the talks in his favour, as well as promote his own scientific achievements. Diplomacy assignments, often dangerous as well as tedious, would occupy much of his time for the next twenty years. His private life, of which much remains unclear, was developing in parallel. Otto von Guericke utilised both his official status and his scientific knowledge in each other's support to serve his city's political agenda. Demonstrations of his inventions, such as the air-pump and the electrostatic generator were meant to impress his audiences and improve and extend political communication. He would, if necessary forgo scientific and technical elaborations on how his showpieces worked, leaving people to believe in his wizardry, a characteristic that was of great use for the promotion of a great leader.
https://en.wikipedia.org/wiki?curid=49828
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The biological role of this protein is also well understood. The demethylated products of the CYP51 reaction are vital intermediates in pathways leading to the formation of cholesterol in humans, ergosterol in fungi, and other types of sterols in plants. These sterols localize to the plasma membrane of cells, where they play an important structural role in the regulation of membrane fluidity and permeability and also influence the activity of enzymes, ion channels, and other cell components that are embedded within. With the proliferation of immuno-suppressive diseases such as HIV/AIDS and cancer, patients have become increasingly vulnerable to opportunistic fungal infections (Richardson et al.). Seeking new means to treat such infections, drug researchers have begun targeting the 14α-demethylase enzyme in fungi; destroying the fungal cell's ability to produce ergosterol causes a disruption of the plasma membrane, thereby resulting in cellular leakage and ultimately the death of the pathogen ("DrugBank").
https://en.wikipedia.org/wiki?curid=14046249
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2015: On 5 September, "Healy" became the first unaccompanied United States surface vessel to reach the North Pole. "Healy" travelled over 16,000 nautical miles during Arctic West Summer 2015 (AWS15). During this expedition, more than 25,000 water and ice samples from 72 science stations were collected through Conductivity, Temperature, Depth (CTD) casts and on-ice science stations. "Healy" worked with both the United States Coast Guard Research & Development Center and the National Oceanic and Atmospheric Administration to test and develop Unmanned Aerial Vehicles (UAV's), and became the first vessel to broadcast a live feed from Arctic waters. "Healy" also conducted a professional international engagement with the German Icebreaker Polarstern at the North Pole. It was a historic Arctic deployment that displayed the Coast Guard's unique polar capabilities to the public and the world. Between May and October 2015, "Healy" also tested the Mobile User Objective System (MUOS) high frequency satellite communication system throughout her Arctic Summer West 2015 mission. Successful tests were completed throughout the expedition during the transit to the North Pole.
https://en.wikipedia.org/wiki?curid=274594
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For sufficiently smooth formula_74 the operator defined above is compact on reasonable Banach spaces such as the formula_59. F. Riesz theory states that the set of singular values of such an operator contains zero (hence the existence of a null-space), is finite or at most countable, and, in the latter case, they constitute a sequence that goes to zero. In the case of a symmetric kernel, we have an infinity of eigenvalues and the associated eigenvectors constitute a hilbertian basis of formula_59. Thus any solution of this equation is determined up to an additive function in the null-space and, in the case of infinity of singular values, the solution (which involves the reciprocal of arbitrary small eigenvalues) is unstable: two ingredients that make the solution of this integral equation a typical ill-posed problem! However, we can define a solution through the pseudo-inverse of the forward map (again up to an arbitrary additive function). When the forward map is compact, the classical Tikhonov regularization will work if we use it for integrating prior information stating that the formula_59 norm of the solution should be as small as possible: this will make the inverse problem well-posed. Yet, as in the finite dimension case, we have to question the confidence we can put in the computed solution. Again, basically, the information lies in the eigenvalues of the Hessian operator. Should subspaces containing eigenvectors associated with small eigenvalues be explored for computing the solution, then the solution can hardly be trusted: some of its components will be poorly determined. The smallest eigenvalue is equal to the weight introduced in Tikhonov regularization.
https://en.wikipedia.org/wiki?curid=203956
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There is enormous potential for renewable energy in Kazakhstan, particularly from wind and small hydropower plants. The Republic of Kazakhstan has the potential to generate 10 times as much power as it currently needs from wind energy alone. But renewable energy accounts for just 0.6 percent of all power installations. Of that, 95 percent comes from small hydropower projects.<ref name="http://www.eurasia.undp.org/"></ref> The main barriers to investment in renewable energy are relatively high financing costs and an absence of uniform feed-in tariffs for electricity from renewable sources. The amount and duration of renewable energy feed-in tariffs are separately evaluated for each project, based on feasibility studies and project-specific generation costs. Power from wind, solar, biomass and water up to 35 MW, plus geothermal sources, are eligible for the tariff and transmission companies are required to purchase the energy of renewable energy producers. An amendment that introduces and clarifies technology-specific tariffs is now being prepared. It is expected to be adopted by Parliament by the end of 2014. In addition, the World Bank's Ease of Doing Business indicator shows the country to be relatively investor-friendly, ranking it in 10th position for investor protection.
https://en.wikipedia.org/wiki?curid=50433642
1,557,954
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In 2006 was appointed as Dean of Faculty of Applied Science and Engineering, University of Toronto. At the same time she was appointed as Alumni Chair Professor in BioEngineering at the Department of Mechanical and Industrial Engineering. Her achievements in education cover the whole spectrum of integrating education, research and engineering practice. Dedicated to outreach, she co-developed Engineering Your Future, the Society of Women Engineers workshop for female and minority high school students, and Moving 4th into Engineering, an outreach program targeted toward fourth graders. Other major projects include the development of the Identity, Privacy and Security Institute, which works in collaboration with policymakers, regulatory agencies and industry, plus multidisciplinary centres in sustainable energy and global engineering. In 2003, she received the Hispanic Engineer National Achievement Education Award and, in 2005, she was named one of America's most important Hispanics in technology and business.
https://en.wikipedia.org/wiki?curid=29302481
1,515,983
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One problem with both of these early designs, which are called centrifugal-flow engines, was that the compressor worked by accelerating air outward from the central intake to the outer periphery of the engine, where the air was then compressed by a divergent duct set-up, converting its velocity into pressure. An advantage of this design was that it was already well understood, having been implemented in centrifugal superchargers, then in widespread use on piston engines. However, given the early technological limitations on the shaft speed of the engine, the compressor needed to have a very large diameter to produce the power required. This meant that the engines had a large frontal area, which made it less useful as an aircraft powerplant due to drag. A further disadvantage of the earlier Whittle designs was that the air flow was reversed through the combustion section and again to the turbine and tailpipe, adding complexity and lowering efficiency. Nevertheless, these types of engines had the major advantages of light weight, simplicity and reliability, and development rapidly progressed to practical airworthy designs.
https://en.wikipedia.org/wiki?curid=27888245
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When Hardin took control of the state-wide system, he appointed his longtime colleague Joseph Soshnik to run what had become the University of Nebraska–Lincoln. Soshnik's tenure began in the midst of a transition for the universities of Nebraska, as well as a period of turmoil across many United States campuses as students protested American involvement in the Vietnam War. At Nebraska, this included a student takeover of the ROTC building on May 4, 1970, when a crowd of nearly two thousand protesters and onlookers gathered on campus hours after the Kent State shootings. Administration responded to protests by meeting and negotiating with student leaders, and as a result, no Vietnam War protests at the University of Nebraska–Lincoln became violent or required a National Guard intervention. Student leaders later praised Soshnik and anti-war professor Paul Olson for maintaining communication and allowing students to "vent their frustrations." Minor protests were held in January 1971 when President Richard Nixon visited Lincoln to honor the school's national championship-winning football team. Nebraska won its second consecutive national title the following year, in the process defeating archrival Oklahoma 35–31 in what was dubbed "The Game of the Century".
https://en.wikipedia.org/wiki?curid=323058
315,015
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Ecosystems, even those with seemingly distinct borders, rarely function independently of other adjacent systems. Ecologists are increasingly recognizing the important effects that cross-ecosystem transport of energy and nutrients have on plant and animal populations and communities. A well known example of this is how seabirds concentrate marine-derived nutrients on breeding islands in the form of feces (guano) which contains ~15–20% nitrogen (N), as well as 10% phosphorus. These nutrients dramatically alter terrestrial ecosystem functioning and dynamics and can support increased primary and secondary productivity. However, although many studies have demonstrated nitrogen enrichment of terrestrial components due to guano deposition across various taxonomic groups, only a few have studied its retroaction on marine ecosystems and most of these studies were restricted to temperate regions and high nutrient waters. In the tropics, coral reefs can be found adjacent to islands with large populations of breeding seabirds, and could be potentially affected by local nutrient enrichment due to the transport of seabird-derived nutrients in surrounding waters. Studies on the influence of guano on tropical marine ecosystems suggest nitrogen from guano enriches seawater and reef primary producers.
https://en.wikipedia.org/wiki?curid=60927729
482,085
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Ecosystems, even those with seemingly distinct borders, rarely function independently of other adjacent systems. Ecologists are increasingly recognizing the important effects that cross-ecosystem transport of energy and nutrients have on plant and animal populations and communities. A well known example of this is how seabirds concentrate marine-derived nutrients on breeding islands in the form of feces (guano) which contains ~15–20% nitrogen (N), as well as 10% phosphorus. These nutrients dramatically alter terrestrial ecosystem functioning and dynamics and can support increased primary and secondary productivity. However, although many studies have demonstrated nitrogen enrichment of terrestrial components due to guano deposition across various taxonomic groups, only a few have studied its retroaction on marine ecosystems and most of these studies were restricted to temperate regions and high nutrient waters. In the tropics, coral reefs can be found adjacent to islands with large populations of breeding seabirds, and could be potentially affected by local nutrient enrichment due to the transport of seabird-derived nutrients in surrounding waters. Studies on the influence of guano on tropical marine ecosystems suggest nitrogen from guano enriches seawater and reef primary producers.
https://en.wikipedia.org/wiki?curid=65970498
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The Avenger was also used by the Royal Navy's Fleet Air Arm, where it was initially known as the "Tarpon". Initial test flights were carried out by British Admiralty test pilot Roy Sydney Baker-Falkner at RAF Boscombe Down. However, this name was later discontinued and the Avenger name used instead, as part of the process of the Fleet Air Arm universally adopting the U.S. Navy's names for American naval aircraft. The first 402 aircraft were known as Avenger Mk I, 334 TBM-1s from Grumman were called the Avenger Mk II, and 334 TBM-3 were designated the Mk III. An interesting kill by a Royal Navy Avenger was the destruction of a V-1 flying bomb on 9 July 1944. The much faster V-1 was overtaking the Avenger when the Telegraphist Air Gunner in the dorsal turret, Leading Airman Fred Shirmer, fired at it from . For this achievement, Shirmer was Mentioned in Dispatches, later being awarded the DSM for the 1945 Operation Meridian action at Palembang. In the January 1945 British carrier raid on the Soengei Gerong oil refinery during Operation Meridian, a Fleet Air Arm Avenger shot down a Nakajima Ki-44 "Tojo" in low level combat over the jungle. Three Avengers were modified to carry the Highball "bouncing bomb" (given the new codename Tammany Hall), but when trials were unsuccessful, they were returned to standard configuration and passed to the Royal Navy.
https://en.wikipedia.org/wiki?curid=507536
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The phrase "crystalline admixtures" is a label that does not necessarily indicate functionality or molecular structure since it is derived from commercially accessible goods whose components are often not specified. Practically, commercial crystalline admixtures may be distinguished from supplementary cementitious materials (SCMs) by their dosage, generally 1% by cement weight for crystalline admixtures and more than 5% for SCMs. Crystalline admixtures (CA) are categorized as a unique type of permeability-reducing admixtures. The category of permeability reducing admixtures includes a diverse variety of materials, which may also be referred to by the general term "crystalline admixtures." Furthermore, most commercial products include proprietary ingredients, and their formulations are kept secret. However, in general, CAs are extremely hydrophilic products created by "active chemicals" that are often blended with cement and sand. In the presence of water, they react, creating water-insoluble pore/crack-blocking precipitates that improve CSH density and resistance to water penetration. CAs have been demonstrated to enhance the mechanical qualities of concrete when used at 3%, 5%, and 7% of the cement content when exposed to moisture. However, the percentages mentioned above may be fairly high for an addition.
https://en.wikipedia.org/wiki?curid=69140980
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In July 1949, as English Electric was in the process of setting up production at Samlesbury Aerodrome, a firm order was placed for 132 Canberras. The order consisted of 90 B.5/47 bomber-type aircraft, 34 PR.31/46 photo-reconnaissance aircraft, and 8 T.2/49 trainer aircraft. On 25 June 1950, what would become known as the Korean War broke out; this led to a surge of demand for the Canberra and the British government stepping in to establish a far greater level of wartime production. This led to a succession of orders for Canberra B.2s, the initial bomber variant, being placed with Avro, Handley Page, and Short Brothers; for British needs alone, English Electric produced 196 B.2s, Avro and Handley Page manufactured 75 each, and Short completed 60 aircraft – the B.2 variant of the Canberra exceeded the numbers built of any other version. Other nations, notably Australia and the United States of America, also ordered large numbers of Canberras.
https://en.wikipedia.org/wiki?curid=201787
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Initial artist drawings of the aircraft were made public in early 2002. In May 2002, Boeing applied for a patent on variable-sweep, downward-pointing (negative dihedral, or anhedral) winglets to help ground effect vehicles avoid water contact while minimizing aerodynamic drag; the patent drawings show a cylindrical fuselage, which may indicate that a pressurized aircraft was considered at the time, although the final Pelican design has an unpressurized fuselage. The next month, without explicitly naming Boeing as the aircraft originator, the Army cited the Pelican as an emerging technology to improve strategic responsiveness in its 2002 Transformation Roadmap. In July, a U.S. Transportation Command team lead at Scott Air Force Base mentioned the Pelican as a practical solution for moving troops and equipment over long distances. Meanwhile, the designers evaluated three different aircraft sizes with mean takeoff weights of and wingspans of , respectively.
https://en.wikipedia.org/wiki?curid=1879209
721,603
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The KH-8 (BYEMAN codename Gambit-3) was a long-lived series of reconnaissance satellites of the "Key Hole" (KH) series used by the United States from July 1966 to April 1984, and also known as Low Altitude Surveillance Platform. The satellite ejected "film-bucket" canisters of photographic film that were retrieved as they descended through the atmosphere by parachute. Ground resolution of the mature satellite system was better than . There were 54 launch attempts of the 3,000 kilogram satellites, all from Vandenberg Air Force Base, on variants of the Titan III rocket. Three launches failed to achieve orbit. The first one was satellite #5 on April 26, 1967 which fell into the Pacific Ocean after the Titan second stage developed low thrust. The second was satellite #35 on May 20, 1972 which suffered an Agena pneumatic regulator failure and reentered the atmosphere. A few months later, pieces of the satellite turned up in England and the US managed to arrange for their hasty return. The third failure was satellite #39 on June 26, 1973 which suffered a stuck Agena fuel valve. The Bell 8096 engine failed to start and the satellite burned up in the atmosphere. The KH-8 was manufactured by Lockheed. The camera system/satellite was manufactured by Eastman Kodak's A&O Division in Rochester, New York.
https://en.wikipedia.org/wiki?curid=615353
1,391,534
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The field of crystallography, where X-rays are shone through crystals of a solid material, was founded by William Henry Bragg and his son William Lawrence Bragg at the Institute of Physics during and after World War II. Materials science became a major established discipline following the onset of the Silicon Age and Information Age. This led to the development of modern computers and then mobile phones, with the need to make them smaller, faster and more powerful leading to materials science developing smaller and lighter materials capable of dealing with more complex calculations. This in turn enabled computers to be used to solve complex crystallographic calculations and automate crystallography experiments, allowing researchers to design more accurate and powerful techniques. Along with computers and crystallography, the development of laser technology from 1960 onwards led to the development of light-emitting diodes (used in DVD players and smartphones), fibre-optic communication (used in global telecommunications), and confocal microscopy, a key tool in materials science.
https://en.wikipedia.org/wiki?curid=1688179
1,101,132
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Motor learning is an important component of becoming a fluent semantic compaction user. Consistent icon sequencing to produce a word should be considered throughout the process of learning to use semantic compaction devices. The Language Acquisition through Motor Planning (LAMP) strategy aids individuals in developing motor plans paired with auditory output to represent words. Minspeak relies upon the motor-based learning principles that when motor patterns are repeated, these processes become automatic and simplified. Common automated motor patterns include typing on a keyboard without looking, riding a bicycle, or swallowing food and drink. Increased automaticity and simplification with the production of language allows experienced Minspeak users to delegate cognitive attention to their intended message (language) instead of to the formulation of their message. This allows users to focus on communicating a specific message rather than focus on how to build the message by searching for icons across different pages and or screens. The use of LAMP strategies has been associated with increased natural expression through unique combinations of words in non-verbal children with autism. Ideally, once the system of Minspeak is mastered, productions of communication should take less time and effort across communication contexts.
https://en.wikipedia.org/wiki?curid=27554959
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Since 2008, ATR has been a participant in the European Clean Sky Joint Technology Initiative. On 8 July 2015, an ATR 72-600 'green' technology demonstrator performed its first flight; the demonstrator was used for testing new composite materials for insulation, air conditioning systems, electrical distribution systems, and energy dispersal modifications to evaluate their effect on the aircraft's overall efficiency as a contribution to the Clean Sky initiative. ATR's senior vice-president for engineering Alessandro Amendola indicated that the elimination of all uses of bleed air was a key aim in the designing of an all-electric architecture as well as improving engine efficiency; the minimising of peak electrical loads was also a stated priority. During March 2016, a second round of flight trials dedicated the testing of all-electric systems architecture using the demonstrator was completed; analysis is set to continue.
https://en.wikipedia.org/wiki?curid=285018
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Bowlby's first official representations were carried out for the relationship theory in three very controversial lectures in 1957 by the British Psychoanalytical Society in London. The formal origin of attachment theory can be traced to the publication of two 1958 papers, one being Bowlby's "The Nature of the Child's Tie to his Mother", in which the precursory concepts of "attachment" were introduced, and Harry Harlow's "The Nature of Love", based on the results of experiments which showed, approximately, that infant rhesus monkeys spent more time with soft mother-like dummies that offered no food than they did with dummies that provided a food source but were less pleasant to the touch. Bowlby followed this up with two more papers, "Separation Anxiety" (1960a), and "Grief and Mourning in Infancy and Early Childhood" (1960b). At about the same time, Bowlby's former colleague, Mary Ainsworth was completing extensive observational studies on the nature of infant attachments in Uganda with Bowlby's ethological theories in mind. Mary Ainsworth's innovative methodology and comprehensive observational studies informed much of the theory, expanded its concepts and enabled some of its tenets to be empirically tested. Attachment theory was finally presented in 1969 in "Attachment" the first volume of the "Attachment and Loss" trilogy. The second and third volumes, "Separation: Anxiety and Anger" and "Loss: Sadness and Depression" followed in 1972 and 1980 respectively. "Attachment" was revised in 1982 to incorporate more recent research.
https://en.wikipedia.org/wiki?curid=18756845
1,165,366
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Robert Millikan was Vice Chairman of the National Research Council during World War I. During that time, he helped to develop anti-submarine and meteorological devices. He received the Chinese Order of Jade. After the War, Millikan contributed to the works of the League of Nations' Committee on Intellectual Cooperation (from 1922, in replacement to George E. Hale, to 1931), with other prominent researchers (Marie Curie, Albert Einstein, Hendrik Lorentz, etc.). Millikan was a member of the organizing committee of the 1932 Los Angeles Olympics, and in his private life was an enthusiastic tennis player. He was married and had three sons, the eldest of whom, Clark B. Millikan, became a prominent aerodynamic engineer. Another son, Glenn, also a physicist, married the daughter (Clare) of George Leigh Mallory of "Because it's there" Mount Everest fame. Glenn was killed in a climbing accident in Cumberland Mountains in 1947.
https://en.wikipedia.org/wiki?curid=49008
1,013,356
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The N001 radar for the Su-27 was designed by Viktor Grishin. Pushing the state of the art for the USSR, the original design, known as Mech, was supposed to draw heavily on technologies developed for the experimental Soyuz radar program led by NPO Istok. It was intended to have a great deal of commonality with the MiG-29's N019 Rubin radar. N001 has a 1.075m antenna diameter twist-cassegrain antenna. A pulse-doppler design operating in the 3 cm band using medium and high PRFs for optimum lookdown capability, the N001 has a search range of 80–100 km against a 3m m RCS target in a headon engagement, 140 km against a large bomber. It can track a 3m target at 65 km. In a pursuit engagement, search range for a 3m target falls to just 40 km. Azimuth limits are ±60. Initial units had a MTBF of only 5 hours, but later type is 100 hours; MTBF was eventually brought up to 200 hours. The Su-33 used an updated SUV-33 control system, the N001 radar was largely unchanged but with sea optimised lookdown capability and support for the carrier-based GCI system.
https://en.wikipedia.org/wiki?curid=16309759
1,147,116
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The key instrument for cryosection is the cryostat, which is essentially a microtome inside a freezer. The microtome can be compared to a very accurate "deli" slicer, capable of slicing sections as thin as 1 micrometre. The usual histology slice is cut at 5 to 10 micrometres. The surgical specimen is placed on a metal tissue disc which is then secured in a chuck and frozen rapidly to about –20 to –30 °C. The specimen is placed in a gel-like embedding medium, usually OCT which consists of polyethylene glycol and polyvinyl alcohol; this compound is known by many names and when frozen has the same density as frozen tissue. At this temperature, most tissues become rock-hard. Usually a lower temperature is required for fat or lipid rich tissue. Each tissue has a preferred temperature for processing. Subsequently, it is cut frozen with the microtome portion of the cryostat, the section is picked up on a glass slide and stained (usually with hematoxylin and eosin, the H&E stain). The preparation of the sample is much more rapid than with traditional histology technique (around 10 minutes vs 16 hours). However, the technical quality of the sections is much lower. The entire laboratory can occupy a space less than , and minimal ventilation is required compared to a standard wax embedded specimen laboratory.
https://en.wikipedia.org/wiki?curid=3690483
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On the other hand, the Soviets did not treat SEAD as an independent air operation but as a tactical role to be performed as part of a larger mission, namely an overwhelming air assault against NATO. This role was not carried out by SEAD-specific aircraft but normal bombers and fighter aircraft, such as the Tupolev Tu-16 and Tupolev Tu-22M, which could carry Soviet anti-radiation missiles. These aircraft would be organized into several strike groups whose mission was to lay down "chaff corridors" 40–50 kilometers across at intervals of 10 kilometers, including directly on top of suspected SAM sites. A small number of aircraft in these groups would be equipped with ARMs to physically destroy the sites. These missions were conducted against pre-planned targets which had been previously identified by signals intelligence and other reconnaissance efforts, rather than having aircraft seek out targets of opportunity. The closest the Soviets came to dedicated SEAD platforms were modified stand-off interceptors like the Mikoyan MiG-25BM and attack aircraft like the Sukhoi Su-24M.
https://en.wikipedia.org/wiki?curid=573491
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H" (i.e. "H"-infinity") methods are used in control theory to synthesize controllers to achieve stabilization with guaranteed performance. To use "H" methods, a control designer expresses the control problem as a mathematical optimization problem and then finds the controller that solves this optimization. "H" techniques have the advantage over classical control techniques in that "H" techniques are readily applicable to problems involving multivariate systems with cross-coupling between channels; disadvantages of "H" techniques include the level of mathematical understanding needed to apply them successfully and the need for a reasonably good model of the system to be controlled. It is important to keep in mind that the resulting controller is only optimal with respect to the prescribed cost function and does not necessarily represent the best controller in terms of the usual performance measures used to evaluate controllers such as settling time, energy expended, etc. Also, non-linear constraints such as saturation are generally not well-handled. These methods were introduced into control theory in the late 1970s-early 1980s
https://en.wikipedia.org/wiki?curid=314366
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The EIB then signed a €100 million loan in June 2020, after an accelerated approval (two months for a process that usually takes more than a year). This financing helped BioNTech's vaccine trials and manufacturing. The EIB loan is part of the InnovFin Corporate Research Equity programme and the European Fund for Strategic Investments. This programme supports "innovative and higher-risk projects" backed by the European Investment Bank with a guarantee from the European Union budget. In 17 March 2020, BioNTech received a $135 million investment from Fosun Pharma in exchange for 1.58 million shares in BioNTech and the future development and marketing rights of the mRNA vaccine BNT162b2 in China. In June 2020, BioNTech received €250 million from Temasek Holdings (Singapore) via the purchase of ordinary shares and 4 years convertible notes, but also from other investors through a private placement of mandatory convertible bonds. On 15 September 2020, the German Federal Ministry of Education and Research (BMBF) awarded a €375 million grant to BioNTech, to accelerate the development of the COVID-19 vaccine.
https://en.wikipedia.org/wiki?curid=64671486
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Jager made her first appearance for the Danish national team at the 2009 Archery World Cup. She later participated in the 2010 European Archery Championships and the 2011 World Archery Championships, where she finished ninth overall in the women's individual competition. The following year she made her Olympic debut at the 2012 Summer Olympics in London. She and teammates Carina Christiansen and Louise Laursen comprised Denmark's three-person entry for the women's team event, the nation's debut in the discipline. In the preliminary ranking round, which determined the seedings for the subsequent elimination rounds, the trio set a new Danish national record of 1,946 points over the 216-arrow contest, finishing with the eighth seed of the twelve competing nations. Victory over India in the first knockout round saw them advance to the quarter-finals, where they were eliminated by South Korea.
https://en.wikipedia.org/wiki?curid=36566969
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Envihab is a medical research facility of the Institute of Aerospace Medicine of the German Aerospace Center (DLR) where the effects of diverse environmental conditions on humans are being analyzed and explored as well as possible countermeasures are being developed. The name Envihab is a combination of the words “environment” and “habitat” (Latin: home/living space). The concept of Envihab is to deal with complex problems of a life support system and the interaction between humans and the environment from a medical, biological and psychological point of view. Major focus will be put on research topics that deal with providing for health and performance of humans. The modular house-in-house concept makes it possible to use the different units and the technical equipment without leaving the building. 12 test persons can permanently be exposed to equal and controlled environmental conditions. Total floor space of :envihab is approx. 3.500 square meters.
https://en.wikipedia.org/wiki?curid=33386360
2,073,167
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In 1770 he travelled to Saint Petersburg as the secretary of Admiral Charles Knowles, where he taught mathematics to the cadets at the Naval Academy at Kronstadt, obtaining a double salary and the rank of lieutenant colonel. Robison moved to Scotland in 1773 and took up the post of Professor of natural philosophy at the University of Edinburgh. He lectured on mechanics, hydrostatics, astronomy, optics, electricity and magnetism. His conception of mechanical philosophy’ became influential in nineteenth-century British physics. His name appears in the 1776 "Minute Book of The Poker Club", a crucible of the Scottish Enlightenment. In 1783 he became General Secretary of the Royal Society of Edinburgh and in 1797 his articles for the "Encyclopædia Britannica" gave a good account of the scientific, mathematical and technological knowledge of the day. He also prepared for publication, in 1799, the chemical lectures of his friend and mentor, Joseph Black.
https://en.wikipedia.org/wiki?curid=2219052
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In 1970, paleontologists began studying the Cretaceous–Paleogene extinction in a detailed, rigorous way. Benton considered this to be the beginning of the "Professional Phase" of Cretaceous–Paleogene extinction research. Early in this phase, the pace of the extinctions and the potential role of the Deccan Traps volcanism in India were major subjects of interest. In 1980, father and son duo Luis and Walter Alvarez reported anomalously high levels of the platinum group metal iridium from the K–Pg boundary, but because iridium is rare in Earth's crust they argued that an asteroid impact was needed to account for it. This suggestion set off a bitter controversy. Evidence for an impact continued to mount, like the discovery of shocked quartz at the K–Pg boundary. In 1991, Alan Hildebrand and William Boynton reported the Chicxulub crater in the Yucatan peninsula of Mexico as a probable impact site. While the controversy continued, the accumulating evidence gradually began to sway the scientific community toward the Alvarez hypothesis. In 2010, an international panel of researchers concluded that impact best explained the extinction event and that Chicxulub was indeed the resulting crater. Because the estimated date of the object's impact and the Cretaceous–Paleogene boundary (K–Pg boundary) coincide, there is now a scientific consensus that this impact was the Cretaceous–Paleogene extinction event which caused the death of most of the planet's non-avian dinosaurs and many other species. The impactor's crater is just over 177 kilometers in diameter, making it the second largest known impact crater on Earth.
https://en.wikipedia.org/wiki?curid=45249020
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F3B models are called multitask gliders, similar to F3F slope gliders with a lighter composite layup. The design of the F3B model is especially challenging because of the wide range of operating conditions. It must be flown very slowly to achieve the duration time and create high lift to maximize launch altitude off the winch. At the same time it must have very low drag to fly at high speed during the distance and speed tasks. The launch and turning loads require very strong airframes, composite construction has been in use since the first world championship in 1977. Models are typically constructed from carbon fiber, utilizing more exotic high modulus carbon in the wing spars. The empty weight of the airframes have come down substantially since the early 1990s when competitive aircraft weighed 3 kg empty. Many top designs are commercially available from manufacturers such as TUDM, Baudis Model and Samba Model in Europe.
https://en.wikipedia.org/wiki?curid=3582033
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Although lacrosse has seen a 35% surge in participation since 2012, attendance at MLL (Major League Lacrosse) games have decreased and the sport doesn't get the television coverage like other sports in the US do. Paul Rabil, arguably the greatest and most influential lacrosse player of all time, tried to purchase the MLL on several occasions after being tired of poor wages and low attendance at games, but was denied by the MLL. Paul Rabil with his brother, Mike Rabil, would go to create their own lacrosse league known as the PLL (Premier Lacrosse League) in 2018. They received financial support from the Chernin Group, which owns Barstool Sports, and Alibaba co-founder Joseph Tsai. The brothers also signed a contract with NBC, and NBC Sports to broadcast the league games. The PLL offers a $25,000 minimum salary, which was three times more than what MLL players made, plus health-care benefits and equity in the league. The PLL has allowed many professional players to make lacrosse their full-time job, which is why many MLL players are migrating to the PLL, and why many college lacrosse players have chosen the PLL over the MLL and other professional leagues. With the creation of the PLL there was an increase in attendance. In 2019, the PLL's first season, there were over 10,000 attendees at every weekend event and hundreds of thousands watching from home. With proper financial backing, marketing, television broadcasting and distribution, the PLL had a successful first season that saw more viewership and interest than the MLL. It was a historic success.
https://en.wikipedia.org/wiki?curid=1859203
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In 1808, Cuvier identified a fossil found in Maastricht as a giant marine reptile that would later be named "Mosasaurus". He also identified, from a drawing, another fossil found in Bavaria as a flying reptile and named it "Pterodactylus". He speculated, based on the strata in which these fossils were found, that large reptiles had lived prior to what he was calling "the age of mammals". Cuvier's speculation would be supported by a series of finds that would be made in Great Britain over the course of the next two decades. Mary Anning, a professional fossil collector since age eleven, collected the fossils of a number of marine reptiles and prehistoric fish from the Jurassic marine strata at Lyme Regis. These included the first ichthyosaur skeleton to be recognized as such, which was collected in 1811, and the first two plesiosaur skeletons ever found in 1821 and 1823. Mary Anning was only 12 when she and her brother discovered the Ichthyosaurus skeleton. Many of her discoveries would be described scientifically by the geologists William Conybeare, Henry De la Beche, and William Buckland. It was Anning who observed that stony objects known as "bezoar stones" were often found in the abdominal region of ichthyosaur skeletons, and she noted that if such stones were broken open they often contained fossilized fish bones and scales as well as sometimes bones from small ichthyosaurs. This led her to suggest to Buckland that they were fossilized feces, which he named coprolites, and which he used to better understand ancient food chains. Mary Anning made many fossil discoveries that revolutionized science. However, despite her phenomenal scientific contributions, she was rarely recognized officially for her discoveries. Her discoveries were often credited to wealthy men who bought her fossils.
https://en.wikipedia.org/wiki?curid=7991116
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The earliest archaeologists were typically amateurs who would excavate a site with the sole purpose of collecting as many objects as they could for display in museums. Curiosity about past humans and the potential for finding lucrative and fascinating objects justified what many professional archaeologists today would consider to be unethical archaeological behavior. A shift toward scientific knowledge prompted many early archaeologists to begin documenting their finds. In 1906, the Antiquities Act created as the first act in America to help regulate archaeological discovery. This act allowed for federal protection of sites from looting but failed to protect native peoples from having their land and ancestral objects seized. The Society for American Archaeology was developed in 1934. This organization helped to bring regulation into the field of archaeology and provided consistent training for professional archaeologists. A series of laws passed in the 1960s and 1970s created the field of cultural resource management which protects archaeological sites from encroaching development. Debates about the rights of native peoples to their ancestral belongings occurred throughout the 1980s culminating in the passing of the Native American Graves Protection and Repatriation Act. The rise of ethics in archaeology was spurred by a shift in archaeological theory towards post-processualism which focuses on critical evaluation of methods and the implications of archaeology on politics.
https://en.wikipedia.org/wiki?curid=2607695
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At the start of 1967, the brigade had 49 air ambulances in one air ambulance company and four medical detachments (RA) to provide primary evacuation support for US and Free World Military Assistance Forces (FWMAF). Other forces were provided support on an as-available basis, with US and FWMAF receiving priority. The increase in allied troops in Vietnam was not accompanied by an attendant increase in medical aviation resources and the increased evacuation workload placed a strain on the existing aeromedical evacuation resources. Therefore, additional medical aviation units were requested for Vietnam based on projected increases in the US and Free World Military Assistance Forces. Until these added medical aviation units arrived, the increased evacuation requirements were met by a special issue of six helicopters by USARV to augment the medical evacuation capability. The special issue aircraft were assigned to "Dustoff" units according to demonstrated workload requirements. By the end of the year the brigade was performing the aeromedical evacuation mission with two air ambulance companies and eight helicopter ambulance detachments, which represented a doubling of the number of available air ambulances. The additional air ambulance units permitted a greater degree of flexibility in stationing, so as to provide more responsive support. From the widely scattered unit base heliports, individual air ambulances were field sited to increase responsiveness to combat forces engaged in operations. A total of 88,696 patients were evacuated by "Dustoff" units during 1967.
https://en.wikipedia.org/wiki?curid=8709111
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Conservation science studies the process by which the various mechanisms of deterioration cause changes to material culture that affect their longevity for future generations. These mechanisms may produce chemical, physical, or biological changes and differ based on the material properties of the subject at hand. A large portion of conservation science research is the study of the behavior of different materials under a range of environmental conditions. One method used by scientists is to artificially age objects in order to study what conditions cause or mitigate deterioration. The results of these investigations informs the field on the major risk factors as well as the strategies to control and monitor environmental conditions to aid in long term preservation. Further, scientific inquiry has led to the development of more stable and long-term treatment methods and techniques for the types of damages that do occur.
https://en.wikipedia.org/wiki?curid=9962115
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Research shows individuals with traumatic brain injury often suffer memory deficits due to impairment in the acquisition phase. They take far more trials to reach a predetermined learning criterion, but having learned something, their ability to retrieve it is comparable to healthy controls. It is therefore important to aid them in acquiring new skills and memories. Relatively little research has been done examining how learning strategies which benefit healthy people apply to individuals with TBI. Goverover et al. examined the application of the spacing effect in improving functional tasks, such as route learning. Initial performance of the task was better for massed practice, but delayed recall was better for information learned using distributed practice. The longer the delay, the greater the spacing effect. This shows distributed practice has a role in rehabilitation, especially in helping patients with TBI retain new skills.
https://en.wikipedia.org/wiki?curid=34976279
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On October 2, 2009 ISIS posted a subject to revision working document by IAEA safeguards experts which it described as an "Internal IAEA Document on Alleged Iranian Nuclear Weaponization". The document led media to report that Iran has tested a two-point implosion design. Gordon Oehler, who ran the CIA’s nonproliferation center and served as deputy director of the presidential commission on weapons of mass destruction, wrote “if someone has a good idea for a missile program, and he has really good connections, he’ll get that program through.. But that doesn’t mean there is a master plan for a nuclear weapon.” Outside experts noted that the parts of the report made public lack many dates associated with Iran's alleged activities. The Washington Post reported that "nowhere are there construction orders, payment invoices, or more than a handful of names and locations possibly connected to the projects." Former IAEA Director Mohamed ElBaradei said the Agency didn't have any information that nuclear material has been used and didn't have any information that any components of nuclear weapons had been manufactured. Iran asserted that the documents were a fabrication, while the IAEA urged Iran to be more cooperative and Member States to provide more information about the allegations to be shared with Iran.
https://en.wikipedia.org/wiki?curid=4778898
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The first stage, MSIP I, began in February 1980 and it introduced the new technologies that defined the Block 15 aircraft. Fundamentally, MSIP I improvements were focused on reducing the cost of retrofitting future systems. These included structural and wiring provisions for a wide-field-of-view raster HUD; multi-function displays (MFD); advanced fire control computer and central weapons interface unit; integrated Communications/Navigation/Identification (CNI) system; beyond-visual-range (BVR) air-to-air missiles, electro-optical and target acquisition pods, and internal electronic countermeasures (ECM) systems; and increased-capacity environmental control and electrical power systems. Delivery of the first USAF MSIPI Block 15 aircraft occurred in November 1981, and work on the first EPG MSIPI aircraft began in May 1982.
https://en.wikipedia.org/wiki?curid=18895385
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What would become the MB-326 had its origins in a private venture project by Macchi; it was developed by a team headed by Italian aeronautical engineer Ermanno Bazzocchi, the company's technical director and chief engineer. Reportedly, Bazzocchi had considered many different configurations for the tentative trainer before the design team chose to proceed with a single-engined design. In accordance with its intended primary use, the airframe was a robust and light all-metal structure, being relatively simple and cheap to construct and to maintain. The design was also to be powered by the British Armstrong Siddeley Viper turbojet engine, an efficient powerplant for the time. The Viper engine had been originally designed as a short-life unit destined for use upon disposable target drones, however, the engine had showed itself to be far more reliable and useful in other roles. During 1954, initial representations by Bazzochi were made to the Italian Air Ministry. During 1953, the designed airframe and engine combination led to Macchi formally launching the MB-326 programme.
https://en.wikipedia.org/wiki?curid=184400
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Founded in 2006, Algenol Biofuels is a global, industrial biotechnology company that is commercializing its patented algae technology for production of ethanol and other fuels. Based in Southwest Florida, Algenol's patented technology enables the production of the four most important fuels (ethanol, gasoline, jet, and diesel fuel) using proprietary algae, sunlight, carbon dioxide and saltwater for around $1.27 per gallon and at production levels of 8 000 total gallons of liquid fuel per acre per year. Algenol's technology produces high yields and relies on patented photobioreactors and proprietary downstream techniques for low-cost fuel production using carbon dioxide from industrial sources. The company originally intended on producing commercially by 2014, but was set back when Florida Governor Rick Scott signed a bill in 2013 eliminating the state's mandate of a minimum of 10% ethanol in commercial gasoline. This caused Algenol CEO Paul Woods to scrap a plan for a US$500 million plant to produce commercial amounts of algae biofuels and pursue other job sites. Currently, Algenol is a partner of the US Department of Energy's Bioenergy Technologies Office, and in 2015 began smaller-scale commercial sales of E15 and E85 ethanol blends to Protec Fuel, a Florida-based fuel distributor.
https://en.wikipedia.org/wiki?curid=14205946
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On November 20, 1924, President Randolph B. Binnion resigned the presidency to become provost at George Peabody College for Teachers in Nashville, Tennessee, and the board of regents selected Samuel H. Whitley as his successor. Whitley was the Dean of the Faculty at ETSTC and a professor of mathematics at the time of his selection, prior to which he had been a high school principal in Corsicana and, briefly, Assistant State Superintendent. Whitley was inaugurated as ETSTC's third president on January 16, 1926, the same day as the dedication of the Education Building, the first campus building to be paid for by state funds. The building was constructed with an appropriation of $285,000 from the Texas Legislature and was built by the Jones Construction Company of San Antonio; it featured a 2,500-seat auditorium and originally included 35 classrooms. It was later renamed the Arthur C. Ferguson Social Sciences Building and, as of 1993, was still one of the most-used buildings on campus. By that year, all of the buildings constructed during the presidencies of Mayo and Binnion had been demolished and replaced, leaving the Ferguson Social Sciences Building as the oldest structure still standing on campus.
https://en.wikipedia.org/wiki?curid=49869717
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Students can choose from either 36 concentrations or create their own. They can also participate in 55 interdisciplinary certificate programs; since Princeton does not offer an academic minor, the certificates effectively serve as one. Course structure is determined by the instructor and department. Classes vary in their format, ranging from small seminars to medium-sized lecture courses to large lecture courses. The latter two typically have precepts, which are extra weekly discussion sessions that are led by either the professor or a graduate student. The average class meeting time is 3–4 hours a week, although this can vary depending on the course. The student to faculty ratio is 5 to 1, and a majority of classes have fewer than 20 students. In the "Fiske Guide to Colleges", academic culture is considered as "tight-knit, extremely hardworking, highly cooperative, and supportive."
https://en.wikipedia.org/wiki?curid=23922
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Burnham was born in Hebron, Wisconsin in 1904 and grew up in Fort Atkinson, Wisconsin. He attended college first at the University of Minnesota for two years, then transferring to the University of Wisconsin where he earned his BA in 1924, and MS in 1925. He became a graduate assistant of RA Brink studying maize genetics and earned a PhD in genetics with a minor in Plant Pathology in 1929. At this point, he received a National Research Fellowship to travel to Cornell University where he studied under Rollins A. Emerson and alongside Marcus Rhoades and future Nobel Prize winners Barbara McClintock and George Beadle. After Cornell, Burnham went on to work at Harvard with Edward Murray East and then to the California Institute of Technology. He worked with Lewis Stadler at the University of Missouri in 1932–33. In 1934 he was hired as an assistant professor of genetics at the University of West Virginia where he worked on breeding corn and watermelons in addition to continuing his work on maize cytogenetics that he started during his time with Emerson. In 1937 Burham was hired as an associate professor at the University of Minnesota, where he worked until his retirement in 1972.
https://en.wikipedia.org/wiki?curid=47895144
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While is useful for understanding the amount of energy potentially released in a fission reaction, it was not strictly necessary to develop the weapon, once the fission process was known, and its energy measured at 200 MeV (which was directly possible, using a quantitative Geiger counter, at that time). The physicist and Manhattan Project participant Robert Serber noted that somehow "the popular notion took hold long ago that Einstein's theory of relativity, in particular his famous equation , plays some essential role in the theory of fission. Einstein had a part in alerting the United States government to the possibility of building an atomic bomb, but his theory of relativity is not required in discussing fission. The theory of fission is what physicists call a non-relativistic theory, meaning that relativistic effects are too small to affect the dynamics of the fission process significantly." There are other views on the equation's importance to nuclear reactions. In late 1938, the Austrian-Swedish and British physicists Lise Meitner and Otto Robert Frisch—while on a winter walk during which they solved the meaning of Hahn's experimental results and introduced the idea that would be called atomic fission—directly used Einstein's equation to help them understand the quantitative energetics of the reaction that overcame the "surface tension-like" forces that hold the nucleus together, and allowed the fission fragments to separate to a configuration from which their charges could force them into an energetic "fission". To do this, they used "packing fraction", or nuclear binding energy values for elements. These, together with use of allowed them to realize on the spot that the basic fission process was energetically possible.
https://en.wikipedia.org/wiki?curid=422481
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The amount of solar radiation reaching the ground, as well as the formation of cloud droplets occur on the molecular scale, and so they must be parameterized before they can be included in the model. Atmospheric drag produced by mountains must also be parameterized, as the limitations in the resolution of elevation contours produce significant underestimates of the drag. This method of parameterization is also done for the surface flux of energy between the ocean and the atmosphere, in order to determine realistic sea surface temperatures and type of sea ice found near the ocean's surface. Sun angle as well as the impact of multiple cloud layers is taken into account. Soil type, vegetation type, and soil moisture all determine how much radiation goes into warming and how much moisture is drawn up into the adjacent atmosphere, and thus it is important to parameterize their contribution to these processes. Within air quality models, parameterizations take into account atmospheric emissions from multiple relatively tiny sources (e.g. roads, fields, factories) within specific grid boxes.
https://en.wikipedia.org/wiki?curid=1505381
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Since the 1990's Ehrlich has investigated the possible existence of tachyons, that is, hypothetical subatomic particles that travel faster than the speed of light in vacuum, especially tachyonic or superluminal neutrinos, about which much has been written. He has published extensively in this area, including a 2022 review of all searches for evidence of tachyons. Ehrlich is awaiting final results from the KATRIN experiment, whose 2019 and 2021 results agree with both the standard neutrino mass hierarchy having three nearly equal mass neutrinos and his exotic 3 + 3 model. That model, based on an analysis of supernova SN 1987A postulates three doublets of active and sterile neutrinos, having specific masses, one of which is tachyonic having m ~ -0.2 keV Ehrlich's model would also be proven right or wrong if a new supernova were to be observed in our galaxy, but these occur only two or three times per century. Supernovae have been observed in other galaxies, but they are so distant that no neutrinos have yet been detected from them. Ehrlich has written a book on tachyons intended for both the general reader and physicists: "Hunting the Faster than Light Tachyon, and Finding Three Unicorns and a Herd of Elephants", published by CRC Press, Taylor & Francis Group in 2022. The book describes the decades-long search by the author and others for evidence of the reality of tachyons, and more specifically the notion that some neutrinos are tachyons. Among all the known particles, only neutrinos might be tachyons, because neither their m nor their dv = c - v has ever been definitively observed to be positive. Ehrlich has also created educational videos about tachyons and time travel, which can be found on his web site “The Tachyon Nexus.”
https://en.wikipedia.org/wiki?curid=67161912
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Construction of the four prototypes (serial numbers A-5576, A-5577, A-5578, and A-5579) began in August 1919. The first TF was completed on October 1, 1920, with the first flight taking place 12 days later. However, high throttle settings caused the engines to overheat, thus obliging the pilot to undertake an emergency landing at the mouth of the Delaware River. After a brief waiting period to allow the engines to cool, the aircraft was damaged upon collision with an ocean liner's wake during another takeoff attempt. Other problems noted during initial testing were stiff and erratic rudder control while the ailerons exhibited a tendency to roll in directions opposite to that of rudder control. While subsequent modifications to the tail section remedied the stability problems, the propensity of the engines to overheat at high RPM settings remained an ongoing hindrance to the testing procedure, not only causing several premature landings, but ultimately providing the most decisive factor in the TF's subsequent cancellation.
https://en.wikipedia.org/wiki?curid=14342347
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Worldwide, azoxystrobin is registered for use on all important crops. For example, in the European Union and United States, it is registered for use in wheat, barley, oats, rye, soya, cotton, rice, strawberry, peas, beans, onions and many other vegetables. The advantage to the farmer comes in the form of improved yield at harvest. Farmers can act in their best economic interest: the value of the additional yield can be estimated and the total cost of using the fungicide informs the decision to purchase. This cost-benefit analysis by the end user sets a maximum price which the supplier can demand and in practice pesticide prices fluctuate according to the current market value of the crops in which they are used. The estimated annual use of azoxystrobin in US agriculture is mapped by the US Geological Survey and shows an increasing trend from its introduction in 1997 to 2019, the latest date for which figures are available, and now reaching .
https://en.wikipedia.org/wiki?curid=11880615
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Once a new asteroid has been discovered and reported, other observers can confirm the finding and help define the orbit of the newly discovered object. The International Astronomical Union Minor Planet Center (MPC) acts as the global clearing house for information on asteroid orbits. It publishes lists of new discoveries that need verifying and still have uncertain orbits, and it accepts the resulting follow up observations from around the world. Unlike the initial discovery, which typically requires unusual and expensive wide-field telescopes, ordinary telescopes can be used to confirm the object as its position is now approximately known. There are far more of these around the globe, and even a well equipped amateur astronomer can contribute valuable follow-up observations of moderately bright asteroids. For example, the Great Shefford Observatory in the back garden of amateur Peter Birtwhistle typically submits thousands of observations to the Minor Planet Center every year. Nonetheless, some surveys (for example CSS and Spacewatch) have their own dedicated follow up telescopes.
https://en.wikipedia.org/wiki?curid=58017976
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FAI is characterized by abnormal contact between the proximal femur and rim of the acetabulum (hip socket). In most cases, patients present with a deformity in the femoral head, or acetabulum, a poorly positioned femoral-acetabular junction, or any or all of the foregoing. The cause of FAI is currently unknown, but both congenital and acquired etiologies have been put forth. Studies have shown an increased incidence in siblings, suggesting a genetic component. At least one study has also shown a predilection in the white population. It has also been reported to be more common in males. However, there is no concrete evidence to suggest a genetic trait and instead, the most favored theory currently supports that FAI (the cam type in particular) is due to repetitive movements involving the hip ("e.g." squatting) in young athletes. Aggravating activities that are commonly reported include repetitive or prolonged squatting, twisting movements of the hip, like pivoting during athletics, getting in and out of cars, and even sitting for prolonged periods. A combination of these factors may also predispose to a form of FAI; predominantly, a marginal developmental hip abnormality together with environmental factors such as recurrent motion of the legs within a supraphysiologic range.
https://en.wikipedia.org/wiki?curid=20754811
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For silver the limiting frequency is in the far ultraviolet, but for copper and gold it is closer to the visible. This explains the colors of these two metals. At the surface of a metal, resonance effects known as surface plasmons can result. They are collective oscillations of the conduction electrons, like a ripple in the electronic ocean. However, even if photons have enough energy, they usually do not have enough momentum to set the ripple in motion. Therefore, plasmons are hard to excite on a bulk metal. This is why gold and copper look like lustrous metals albeit with a dash of color. However, in colloidal gold the metallic bonding is confined to a tiny metallic particle, which prevents the oscillation wave of the plasmon from 'running away'. The momentum selection rule is therefore broken, and the plasmon resonance causes an extremely intense absorption in the green, with a resulting purple-red color. Such colors are orders of magnitude more intense than ordinary absorptions seen in dyes and the like, which involve individual electrons and their energy states.
https://en.wikipedia.org/wiki?curid=19838
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"Brachiosaurus" differed in its body proportions from the closely related "Giraffatitan". The trunk was about 25 to 30 percent longer, resulting in a dorsal vertebral column longer than the humerus. Only a single complete caudal (tail) vertebra has been discovered, but its great height suggests that the tail was larger than in "Giraffatitan". This vertebra had a much greater area for ligament attachment due to a broadened neural spine, indicating that the tail was also longer than in "Giraffatitan", possibly by 20 to 25percent. In 1988, paleontologist Gregory S. Paul suggested that the neck of "Brachiosaurus" was shorter than that of "Giraffatitan", but in 2009, paleontologist Mike P. Taylor pointed out that two cervical vertebrae likely belonging to "Brachiosaurus" had identical proportions. Unlike "Giraffatitan" and other sauropods, which had vertically oriented forelimbs, the arms of "Brachiosaurus" appear to have been slightly sprawled at the shoulder joints, as indicated by the sideward orientation of the joint surfaces of the coracoids. The humerus was less slender than that of "Giraffatitan", while the femur had similar proportions. This might indicate that the forelimbs of "Brachiosaurus" supported a greater fraction of the body weight than is the case for "Giraffatitan".
https://en.wikipedia.org/wiki?curid=20598015
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For the first "Return to Flight" STS-26, the five-man astronaut crew wore, for the first time, new Launch & Entry Pressure Suits (LES). Resembling the Gemini spacesuit in appearance, but identical in function to the SR-71 partial-pressure suits, the new LES suits featured a one-piece torso-limb suit with a Nomex outer layer (which NASA was able to use on the Shuttle due to the mixed nitrogen/oxygen sea-level atmosphere), closed with a rear-entry zipper, and featuring a full-pressure helmet with a polycarbonate clear faceplate, mechanical seal, and black sunshade, zippered-on gloves (resembling the gloves used by astronaut Alan Shepard on his Mercury space suit), heavy black "paratrooper" style safety boots, and a survival backpack, which is donned prior to entering the Orbiter and contains a parachute, life raft, survival gear, and a 30-minute supply of breathing oxygen and a water tank.
https://en.wikipedia.org/wiki?curid=26700735
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In the war with Spain in 1898 more Citadel alumni volunteered for service than were needed. In World War I, Citadel graduates were among the first contingents of American troops to fight with the Australian, and later British and French divisions; several served prominently with the Marine Corps at the Battle of Belleau Wood. The name of the college was officially changed in 1910 to "The Citadel, The Military College of South Carolina"; the word "Academy" had become synonymous with secondary schools and the public had the misconception that the South Carolina Military Academy was a preparatory school. By that time the school had outgrown its facility despite numerous additions, in 1918 the city of Charleston offered the state of South Carolina on the banks of the Ashley River for a new campus on the condition that the state fund the construction. The state accepted the offer on February 26, 1919 and allotted $300,000 towards the construction of a new campus. In 1921 the title of the head of the school was changed from Superintendent to President, Colonel Oliver J. Bond was the last Superintendent and first President of The Citadel.
https://en.wikipedia.org/wiki?curid=48639384
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MSOT detects photoechoes, i.e. ultrasound waves generated by thermo-elastic expansion of a sample (e.g. tissue) after absorption of transient electromagnetic energy. Typically, the sample is illuminated with light pulses in the nanosecond range, although intensity-modulated light can also be used. At least some of the electromagnetic energy absorbed by the sample is converted to heat; the resulting temperature rise, on the order of milli-Kelvins, leads to thermo-elastic expansion of the sample. This creates a pressure wave in the form of a broadband ultrasound wave. The ultrasound waves emitted by the sample are detected by transducers positioned near the sample, usually at multiple positions around it. The amplitude of the pressure wave provides information about the local absorption and propagation of energy in the sample, while the time interval between the illumination pulse and arrival of the ultrasound wave at the detector provides information about the distance between the detector and photoecho source. Optoacoustic data collected over time and at multiple positions around the sample are processed using tomographic reconstruction to produce images of the distribution of photoabsorbers in the sample. Data collected after illumination at single wavelengths allow imaging of the distribution of photoabsorbers that share similar absorption characteristics at the given wavelength. Data collected after illumination with multiple wavelengths allow specific distinction of photoabsorbers with different optical absorption spectra, such as oxy- and deoxy-hemoglobin, myoglobin, melanin or exogenous photoabsorbers. The wavelengths of light used to illuminate samples in MSOT are selected based on the absorption characteristics of the target photoabsorbers. To resolve the individual photoabsorbers, images obtained at multiple wavelengths must be further processed using subtraction or spectral unmixing techniques. Background in images can be reduced by exploiting differences in time (baseline subtraction) and in absorption spectra of the various photoabsorbers (spectral unmixing).
https://en.wikipedia.org/wiki?curid=37749401
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"Constellation" was the focus of media attention when black members of her crew protested what they saw as systemic racism in the Navy, leading to what some saw as an aborted mutiny in late 1972. "Constellation" returned to the United States on 1 July and prepared to return to the western Pacific in early 1973. Replacement personnel reported aboard while "Constellation" was in the United States until the ship had 250 more men than the ship's berthing could accommodate. "Constellation"s commanding officer ordered administrative (less than honorable) discharges for five black sailors he considered troublemakers. He planned to give early discharges to another 250 men whose enlistments would expire while "Constellation" was overseas. While "Constellation" was conducting exercises off the California coast, a rumor started that the captain was going to give 250 less than honorable discharges to black sailors. The captain scheduled an open meeting for 21:00 3 November to clarify the 250 planned discharges. At noon 3 November a group of 50 black sailors began a sit-in on a portion of the mess deck. On the night of 3–4 November 60 black sailors took control of the scheduled meeting, refused to leave the mess deck, and threatened to "tear up the ship." "Constellation" returned to San Diego on 4 November to offload 130 men, including 12 white sailors, before returning to sea. "Constellation" returned to San Diego on 7 November and the offloaded sailors were transported back to the dock on 9 November, but only 8 boarded their ship. The remaining sailors sat down on the dock to be filmed by television crews and were ultimately transferred to shore stations for mast. Twelve received general discharges, 35 were honorably discharged but not recommended for re-enlistment, and 73 received punishments ranging from loss of pay and reduction in rate to warnings prior to being reassigned to sea duty.
https://en.wikipedia.org/wiki?curid=204536
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Forensic psychotherapy is the application of psychological knowledge to the treatment of offender-patients who commit violent acts against themselves or others. This form of treatment allows for a therapist to potentially understand the offender and their mental state. It gives the individual providing treatment the opportunity to examine further whether the offender’s criminal behavior was a conscious act or not, what exactly their association with violent behavior is, and what possible motives could have driven them. The discipline of forensic psychotherapy is one that requires the involvement of individuals other than simply the therapist and patient. A therapist may collaborate with other professionals, such as physicians, social workers, and other psychologists in order to best serve the offenders’ needs. Whether the treatment is successful or not relies on a multitude of things, but typically ensuring that a systemic approach is taken and that all involved in the treatment process are well informed and supportive has proven to be the most effective. In addition to group work, forensic psychotherapy may also involve therapeutic communities, individual interaction with victims as well as offenders, and family work. In order for this specialized therapy to be as effective as possible, it demands the compliance of not only the patient and therapist, but of the rest of society as well. The main focus of forensic psychotherapy is to obtain a psychodynamic understanding of the offender in order to attempt to provide them with an effective form of treatment. Guidelines have been set to ensure proficiency in the field of Forensic Psychology.
https://en.wikipedia.org/wiki?curid=10521948
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