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The combination of whole-head DSI datasets acquired and processed according to the approach developed by Hagmann et al. (2007) with the graph analysis tools conceived initially for animal tracing studies (Sporns, 2006; Sporns, 2007) allow a detailed study of the network structure of human cortical connectivity (Hagmann...
https://en.wikipedia.org/wiki?curid=15978180
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In the late 1980s, Hadfield attended the U.S. Air Force Test Pilot School at Edwards Air Force Base and served as an exchange officer with the U.S. Navy at Strike Test Directorate at the Patuxent River Naval Air Station. His accomplishments from 1989 to 1992 included testing the McDonnell Douglas F/A-18 Hornet and LTV ...
https://en.wikipedia.org/wiki?curid=78114
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Dinocaridids were bilaterally symmetrical, with a mostly non-mineralized cuticle and a body divided into two major groupings of tagmata (body-sections): head and trunk. The head apparently unsegmented and had a pair of specialized frontal appendages just in front of the mouth and eyes. The frontal appendages are either...
https://en.wikipedia.org/wiki?curid=2510070
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The largest university in the Chicago area, UIC serves approximately 34,000 students within 16 colleges & schools including Applied Health Sciences, Architecture, Design, and the Arts, Business Administration, Dentistry, Education, Engineering, Graduate, Honors, Liberal Arts & Sciences, Nursing, Pharmacy, Public Health...
https://en.wikipedia.org/wiki?curid=148541
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On the 22 June 1941, Nazi Germany commenced Operation Barbarossa and invaded the Soviet Union along a 2,900-kilometre front. Such was the rapidity and depth of penetration of the attack that, by September, the Red Army's BW facility - the Sanitary Technical Institute ("STI") - on Gorodomlya Island, was under immediate ...
https://en.wikipedia.org/wiki?curid=11564525
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Due to the lower specific fuel consumption and higher thrust rating, the design of the A340 was modified. Compared to the original design's range of 7,000 nautical miles, the revised version – designated the A340-200 – was projected to have a range up to 8,000 nautical miles with full passenger load. Airbus decided on ...
https://en.wikipedia.org/wiki?curid=3109527
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Goldstein got his B.S. at Brooklyn College and his Ph.D at Dartmouth College, where he studied magnetospheric cavity mode resonance, a phenomenon in which the Earth's magnetic field traps electromagnetic waves. As a postdoc at Rice University (2000–2003), Goldstein’s job was to interpret and model the brand-new space w...
https://en.wikipedia.org/wiki?curid=11724891
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When the edge cools fast a diffusionless transformation occurs, turning the austenite into very hard martensite. This requires a temperature drop from around 750 °C (cherry-red) to 450 °C (at which point the transformation is complete) in less than a second to prevent the formation of soft pearlite. Because the rest of...
https://en.wikipedia.org/wiki?curid=182203
1,417,589
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On 23 March 1983, President Ronald Reagan announced a new national missile defense program formally called the Strategic Defense Initiative but soon nicknamed "Star Wars" by detractors. President Reagan's stated goal was not just to protect the U.S. and its allies, but to also provide the completed system to the USSR, ...
https://en.wikipedia.org/wiki?curid=350551
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Warfarin first came into large-scale commercial use in 1948 as a rat poison. Warfarin was formally approved for human use by the U.S. Food and Drug Administration to treat blood clots in 1954. In 1955, warfarin's reputation as a safe and acceptable treatment was bolstered when President Dwight D. Eisenhower received wa...
https://en.wikipedia.org/wiki?curid=238097
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The United States began a system of passive, fixed ocean surveillance systems in 1950 with the classified name Sound Surveillance System (SOSUS) with American Telephone and Telegraph Company (AT&T), with its Bell Laboratories research and Western Electric manufacturing entities being contracted for development and inst...
https://en.wikipedia.org/wiki?curid=29438
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Concurrently with (but separate from) the MANET activities, DARPA had funded NASA, MITRE and others to develop a proposal for the Interplanetary Internet (IPN). Internet pioneer Vint Cerf and others developed the initial IPN architecture, relating to the necessity of networking technologies that can cope with the signi...
https://en.wikipedia.org/wiki?curid=2710684
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When the UK canceled its order for the F-111K in 1968, components for the 48 F-111Ks in manufacturing were diverted to FB-111A production. The FB-111A featured longer F-111B wings for greater range and load-carrying ability. The bomber variant had a redesigned aft fuselage and its maximum speed was limited to Mach 2. I...
https://en.wikipedia.org/wiki?curid=202894
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A major threat to both this crucial intermediate trophic level and the entire upwelling trophic ecosystem is the problem of commercial fishing. Since upwelling regions are the most productive and species rich areas in the world, they attract a high number of commercial fishers and fisheries. On one hand, this is anothe...
https://en.wikipedia.org/wiki?curid=105659
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The award of the 2012 Summer Olympics to London has brought the question of British participation in the football tournaments to the fore, given that there is traditionally no single British national football team. The British Olympic Association initially refused to rule out the possibility of entry for 2008, but were...
https://en.wikipedia.org/wiki?curid=14879786
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The director of the programme was Richard Fothergill. By April 1981 he had set up a small team of people, operating from offices at Cheviot House in Newcastle Polytechnic. John Anderson was appointed Deputy, and the rest of the central team consisted of Bob Coates, Helen Hindess, Mike Bostock and Lynn Craig later suppo...
https://en.wikipedia.org/wiki?curid=3026202
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FPLC was developed and marketed in Sweden by Pharmacia in 1982, and was originally called fast performance liquid chromatography to contrast it with HPLC or high-performance liquid chromatography. FPLC is generally applied only to proteins; however, because of the wide choice of resins and buffers it has broad applicat...
https://en.wikipedia.org/wiki?curid=3865434
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Sanderson and Way (1977) used symbols to notate seventeen different strokes, as well as incorporating court plans for recording accurate positional information. The system took an estimated 5–8 hours of use and practise before an operator was sufficiently skillful to record a full match actually during the game. In an ...
https://en.wikipedia.org/wiki?curid=2883565
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William A. Goddard (July 10, 1913 in St. Joseph, Missouri – September 29, 1997 in Chico, California) was an American engineer and inventor. He earned a degree in physics from Occidental College. Before working in industry, Goddard was a high school science teacher in Los Angeles. He briefly worked in the aerospace indu...
https://en.wikipedia.org/wiki?curid=18201014
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Prions, the infectious agent of CJD, may not be inactivated by means of routine surgical instrument sterilization procedures. The World Health Organization and the US Centers for Disease Control and Prevention recommend that instrumentation used in such cases be immediately destroyed after use; short of destruction, it...
https://en.wikipedia.org/wiki?curid=5617
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Apart from the neotype, other fossils are known of "Scelidosaurus". In 1888 Lydekker catalogued a large number of single bones, largely limb elements, and osteoderms, that had been acquired by the BMNH from the Norris collection. Owen in 1861 described a second, partial, skeleton of a juvenile animal, that later was ad...
https://en.wikipedia.org/wiki?curid=2469650
435,054
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Like his father before him, Cade left his young family to fight for Australia in the Armed Forces in World War II. Cade was appointed captain, Australian Army Medical Corps, A.I.F., on 1 July 1940 and posted to the 2nd/9th Field Ambulance. Although trained as a psychiatrist, Dr. Cade served as a surgeon and departed fo...
https://en.wikipedia.org/wiki?curid=16285
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There is overwhelming evidence of global disruption of plant communities at the K–Pg boundary. Extinctions are seen both in studies of fossil pollen, and fossil leaves. In North America, the data suggests massive devastation and mass extinction of plants at the K–Pg boundary sections, although there were substantial me...
https://en.wikipedia.org/wiki?curid=44503418
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Due to the shortage of plutonium-238, a new kind of RTG assisted by subcritical reactions has been proposed. In this kind of RTG, the alpha decay from the radioisotope is also used in alpha-neutron reactions with a suitable element such as beryllium. This way a long-lived neutron source is produced. Because the system ...
https://en.wikipedia.org/wiki?curid=211485
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Two subtypes of autism were described between 1943 and 1944 by two Austrian researchers — Austrian-born Asperger and child psychiatrist Leo Kanner (1894–1981). Kanner emigrated to the United States in 1924; he described a similar syndrome in 1943, known as "classic autism" or "Kannerian autism", characterized by signif...
https://en.wikipedia.org/wiki?curid=13302907
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The spore sac is variable in shape, ranging from roughly spherical to egg-shaped or irregular, but it is usually taller than it is wide. Its diameter ranges between , although it is most commonly between . An apophysis (a swelling on the underside of the spore sac) is often present. The stalk is visible when the pseudo...
https://en.wikipedia.org/wiki?curid=28846678
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The idea of rocket propulsion by combustion of explosive substance was first proposed by Russian explosives expert Nikolai Kibalchich in 1881, and in 1891 similar ideas were developed independently by German engineer Hermann Ganswindt. Robert A. Heinlein mentions powering spaceships with nuclear bombs in his 1940 short...
https://en.wikipedia.org/wiki?curid=322533
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Amtrak ordered its first 30 F40PHs on May 8, 1975; the first of the new locomotives entered service on April 9 the following year. Amtrak intended the locomotives for short routes such as the "San Diegan" in California and Northeast Corridor services in the then non-electrified portion between New Haven, Connecticut an...
https://en.wikipedia.org/wiki?curid=1081444
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The hypothesis above is closely associated with Jennifer Francis, who had first proposed it in a 2012 paper co-authored by Stephen J. Vavrus. While some paleoclimate reconstructions have suggested that the polar vortex becomes more variable and causes more unstable weather during periods of warming back in 1997, this w...
https://en.wikipedia.org/wiki?curid=16472
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Cognitive interviewing is rooted in two cognitive theories: the encoding specificity principle and the multi-component view of memory. The encoding specificity principle was introduced by Endel Tulving. This theory states that cues presented will be more effective in facilitating recall when the cues have some degree o...
https://en.wikipedia.org/wiki?curid=15767995
1,237,154
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Tuberculosis was the leading cause of death in Europe and North America in the 19th century, accounting for about 40% of working-class deaths in cities, and by 1918 one in six deaths in France were still caused by tuberculosis. European governments, and medical professionals in Canada, were well aware that tuberculosis...
https://en.wikipedia.org/wiki?curid=5090455
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One of the first methods of interprocess communication in Windows was Dynamic Data Exchange (DDE), first introduced in 1987, that allowed sending and receiving messages in so-called "conversations" between applications. Antony Williams, who was involved in the creation of the COM architecture, later distributed two int...
https://en.wikipedia.org/wiki?curid=17058007
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The immunosuppressive effects of clofazimine were immediately noticed when applied in animal model. Macrophages were first reported to be inhibited due to the stabilization of lysosomal membrane by clofazimine. Clofazimine also showed a dosage-dependent inhibition of neutrophil motility, lymphocyte transformation, mito...
https://en.wikipedia.org/wiki?curid=3321174
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This change in tactics resulted in a sudden increase in the rate of irreplaceable losses to the Luftwaffe day fighter force, as their heavily laden aircraft were "bounced" long before reaching the bombers. Within weeks, many of their aces were dead, along with hundreds of other pilots, and the training program could no...
https://en.wikipedia.org/wiki?curid=153227
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For ignition, diesel, PPC and HCCI engines rely solely on the high temperature and pressure created by the engine in its compression process. The compression level that occurs is usually twice or more than a gasoline engine. Diesel engines take in air only, and shortly before peak compression, spray a small quantity of...
https://en.wikipedia.org/wiki?curid=41228673
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Related to adaptive maternal effects are epigenetic effects. Epigenetics is the study of long lasting changes in gene expression that are produced by modifications to chromatin instead of changes in DNA sequence, as is seen in DNA mutation. This "change" refers to DNA methylation, histone acetylation, or the interactio...
https://en.wikipedia.org/wiki?curid=343457
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The development of the design by Sir John Carden at Vickers-Armstrongs Ltd began in 1935. The General Staff specification required a cheap tank, requiring the use of already commercially available components. It resulted in a small two-man vehicle with a low hull and a small cast turret. The turret was fitted with a si...
https://en.wikipedia.org/wiki?curid=1481345
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The HDD's electronics control the movement of the actuator and the rotation of the disk and perform reads and writes on demand from the disk controller. Feedback of the drive electronics is accomplished by means of special segments of the disk dedicated to servo feedback. These are either complete concentric circles (i...
https://en.wikipedia.org/wiki?curid=13777
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The bridge carries Mill Road across a deep ravine about 100 feet (30 m) west of Normanskill Drive. The surrounding area is wooded; to the west of the ravine the woods give way almost immediately to the Stevens Farm complex. The ravine is dry most of the time, but after heavy rains it carries water from a small basin ex...
https://en.wikipedia.org/wiki?curid=29319934
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NBC executives reviewed the plot for "Space Seed" and approved it, but Justman reassessed the outline, saying that it needed to be heavily revised. In September, Wilber was given a list of suggested changes including asking him to remove any mention of the setting, as the producers did not want to say how far in the fu...
https://en.wikipedia.org/wiki?curid=413157
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The Bill and Melinda Gates Foundation is sponsoring a multi-year study of value-added modeling with their Measures of Effective Teaching program. Initial results, released in December 2010, indicate that both value-added modeling and student perception of several key teacher traits, such as control of the classroom and...
https://en.wikipedia.org/wiki?curid=28661419
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The 1.5 B-Series would also form the basis of the 1958 Perkins 4.99 / 1.6 L (1,622 cc) diesel, which was fitted in cars, boats and commercial vehicles including London Taxis like the Beardmore Mk7 Paramount taxi, Ford Thames 400E, early Ford Transits, Bedford CA, Vauxhall Victor, Hillman Minx, Standard Ensign and Moskv...
https://en.wikipedia.org/wiki?curid=1376598
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasio...
https://en.wikipedia.org/wiki?curid=14800103
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The production of [ML] in the reaction above by the "following" chemical reaction produces a species directly at the electrode that could display redox chemistry anywhere in a CV plot or none at all. The change in coordination from [ML] to [ML] often prevents the observation of "reversible" behavior during electrochemi...
https://en.wikipedia.org/wiki?curid=16102721
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Deutsch and Norman were not fully convinced by Broadbent's selection criteria based solely on physical features of a stimulus. For example, the cocktail party effect influenced researchers to look further than physical selection features, to semantic selecting features. The cocktail party effect is an example of how un...
https://en.wikipedia.org/wiki?curid=34780199
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After the men's national team had been able to hold their own for a few years in the lower regions of the top division, the beginning of the 21st century saw a constant ups and downs between the top 16 nations and Division I. Most recently, the team rose to the top of the ice hockey team. World Cup 2009 in Switzerland....
https://en.wikipedia.org/wiki?curid=35607640
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The history of the training centre in Pécs began in the 1973/1974 academic year of the Pécs Teacher Training College with the establishment of the "Cultural Studies Research Group". When the college became a university faculty, the department became the Department of Cultural Studies within the Janus Pannonius Universi...
https://en.wikipedia.org/wiki?curid=2519422
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The first resident crew, Expedition 1, arrived in November 2000 on Soyuz TM-31. At the end of the first day on the station, astronaut Bill Shepherd requested the use of the radio call sign ""Alpha"", which he and cosmonaut Sergei Krikalev preferred to the more cumbersome ""International Space Station"". The name ""Alph...
https://en.wikipedia.org/wiki?curid=15043
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The enzymatic mechanism is similar to that of other serine proteases. These enzymes contain a catalytic triad consisting of histidine-57, aspartate-102, and serine-195. This catalytic triad was formerly called a charge relay system, implying the abstraction of protons from serine to histidine and from histidine to aspa...
https://en.wikipedia.org/wiki?curid=30652
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The Manitoba Department of Education concluded that financial and institutional barriers seldom hinder access to post-secondary education. Instead, barriers are social and cultural. A 2005 report by the Canadian Policy Research Networks (CPRN), titled "Getting There and Staying There", adds the factor of geography, cit...
https://en.wikipedia.org/wiki?curid=17662648
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NIOSH was created out of the Bureau of Occupational Safety and Health by the Occupational Safety and Health Act of 1970, and began operating on April 28, 1971. New York Senator Jacob Javits sponsored the amendment that created NIOSH. The act established the right to a safe and healthful workplace, and established a sci...
https://en.wikipedia.org/wiki?curid=65213097
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The population inversion in the laser is achieved by the following sequence: electron impact excites the {v1(1)} quantum vibrational modes of nitrogen. Because nitrogen is a homonuclear molecule, it cannot lose this energy by photon emission, and its excited vibrational modes are therefore metastable and relatively lon...
https://en.wikipedia.org/wiki?curid=1119275
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The previous image shows the original piston-and-cylinder diagram used by Carnot in discussing his ideal engine. The figure at right shows a block diagram of a generic heat engine, such as the Carnot engine. In the diagram, the “working body” (system), a term introduced by Clausius in 1850, can be any fluid or vapor bo...
https://en.wikipedia.org/wiki?curid=6118
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By far most information on toxicity of dioxin-like chemicals is based on animal studies utilizing TCDD. Almost all organs are affected by high doses of TCDD. In short-term toxicity studies in animals, the typical effects are anorexia and wasting, and even after a huge dose animals die only 1 to 6 weeks after the TCDD a...
https://en.wikipedia.org/wiki?curid=23789332
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The disease is described as both a mental and behavioural disorder within the ICD-11. Signs and symptoms are cognitive, motor, behavioral, and for a significant proportion of patients, also affective. These changes typically occur over a period of 5–10 years. Signs are typically the same as in other dementias, but main...
https://en.wikipedia.org/wiki?curid=227181
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Despite the memorandum submitted to the that eschewed capital ship construction, Caprivi secretly discussed new ironclads at length with senior naval officers. He instructed ("KAdm"—Rear Admiral) Max von der Goltz, then the Director of the Admiralty's Naval Department, to prepare a list of thirteen questions concerning...
https://en.wikipedia.org/wiki?curid=10865795
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In July 2020 Admiral Philip S. Davidson, the head of United States Indo-Pacific Command advised that he sought funding to construct an Aegis Ashore system in Guam by 2026 both to defend existing U.S. military facilities on Guam and to provide offensive "long-range precision strike capability into the First Island Chain...
https://en.wikipedia.org/wiki?curid=249526
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Coleochaete is a genus of parenchymatous charophyte green algae in the order Coleochaetales. They are haploid, reproduce both sexually and asexually, and have true multicellular organisation, with plasmodesmata communicating between adjacent cells. The plants form flat, sprawling discs on solid surfaces in freshwater s...
https://en.wikipedia.org/wiki?curid=20701618
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The On-Demand Small Unmanned Aircraft System (ODSUAS) is a custom-tailored, miniature 3D printed drone created by the U.S. Army Research Laboratory (ARL) and Georgia Technical Institute’s Aerospace Systems Design Laboratory. It was designed to provide flexible unmanned aircraft vehicle (UAV) support, where soldiers can...
https://en.wikipedia.org/wiki?curid=57895391
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Centering the problems of gender education in the STEM field around gender-based bias evaluations of children relating to anxiety and lack of representation of women. Author Drew H. Bailey mentions how regardless of worldwide striving and progress for gender equality across different societies, the lack of women in STE...
https://en.wikipedia.org/wiki?curid=16973246
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Miller has held positions as a postdoctoral researcher in the evolutionary and adaptive systems group in the School of Cognitive and Computing Sciences at the University of Sussex (1992–94); lecturer in the department of psychology at the University of Nottingham (1995); research scientist at the Center for Adaptive Be...
https://en.wikipedia.org/wiki?curid=2807080
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Movement proteins can assist in unraveling key mechanisms that help control and regulate macromolecule transport within and between plant cells. MPs can use plasmodesmata, however, they are also able to alter and intercept intercellular channels based on if they are fully differentiated or if they are developing cells....
https://en.wikipedia.org/wiki?curid=4293944
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In the Faculty of Arts, Humanities and Business, courses such as honours programmes in Gaelic, Theological Studies, and Scottish History, all reflect the distinctive nature of the region, its past, present and future. The Centre for History is based in Dornoch and teaches a range of undergraduate and postgraduate degre...
https://en.wikipedia.org/wiki?curid=2626773
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Bromellite, as a beryllium-containing mineral, has some uses. Industrially, natural specimens have the potential to be an ore of beryllium. It is one of the reagents that can be used in the manufacture of artificial emeralds. As an additive, bromellite confers high mechanical strength and very high thermal conductivity...
https://en.wikipedia.org/wiki?curid=2723764
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Nearly simultaneously with Einstein, also Minkowski (1908) considered the special case of uniform accelerations within the framework of his spacetime formalism. He recognized that the worldline of such an accelerated body corresponds to a hyperbola. This notion was further developed by Born (1909) and Sommerfeld (1910)...
https://en.wikipedia.org/wiki?curid=1790788
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"Calculating Infinity" was released on September 28, 1999, with Relapse Records issuing it on CD and Hydra Head Records releasing a vinyl edition. The album was released later in Japan on April 5, 2000 featuring bonus tracks "The Mullet Burden", "Sandbox Magician" and "Abe the Cop", all of which were originally feature...
https://en.wikipedia.org/wiki?curid=846067
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By November 1951, Wilkins had evidence that DNA in cells as well as purified DNA had a helical structure. Alex Stokes had solved the basic mathematics of helical diffraction theory and thought that Wilkins's X-ray diffraction data indicated a helical structure in DNA. Wilkins met with Watson and Crick and told them abo...
https://en.wikipedia.org/wiki?curid=234248
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The Whin Sill and associated igneous dykes were intruded into the existing sedimentary sequence during the early Permian around 295 Ma. The thickness of the quartz-dolerite sill averages about 30m. The sill underlies the larger part of the county at depth and appears to extend beneath the North Sea to the east. Thermal...
https://en.wikipedia.org/wiki?curid=40130458
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Given the potential complexity and organisational inertia surrounding the creation of roadmaps, researchers at the University of Cambridge focused on developing a fast-start approach to roadmapping. This approach, called T-Plan, was created in the late 1990s primarily to help organisations take the first step into road...
https://en.wikipedia.org/wiki?curid=1739443
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"Fullmetal Alchemist" has generally been well received by critics. Though the first volumes were thought to be formulaic, critics said that the series grows in complexity as it progresses. Jason Thompson called Arakawa one of the best at creating action scenes and praised the series for having great female characters d...
https://en.wikipedia.org/wiki?curid=424547
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In January 1936, the Air Corps contracted with Boeing for thirteen Y1B-17 Flying Fortress prototypes, enough to equip one squadron for operational testing and a thirteenth aircraft for stress testing, with deliveries made from January to August 1937. The cost of the aircraft disturbed Secretary of War Harry Woodring, w...
https://en.wikipedia.org/wiki?curid=23869026
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These technically rather inferior hydriai are 40–45 cm. high. The bodies of these vases have high and very prominent necks, broad shoulders, and low ring feet in the form of upside-down chalices. Many of the hydriai are misshapen or show faulty firing. The painted images are in four zones: a shoulder zone, a belly zone...
https://en.wikipedia.org/wiki?curid=1076046
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Myeloid differentiation primary response gene 88 deficiency (MyD88) is a disorder of the innate immune system. It belongs to rare primary immunodeficiency characterized by an increased susceptibility to certain types of bacterial infections. Patients suffer from abnormally frequent and severe infections by a subset of ...
https://en.wikipedia.org/wiki?curid=56598639
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Whereas during the nineteenth and most of the twentieth century, new plesiosaurs were described at a rate of three or four novel genera each decade, the pace suddenly picked up in the 1990s, with seventeen plesiosaurs being discovered in this period. The tempo of discovery accelerated in the early twenty-first century,...
https://en.wikipedia.org/wiki?curid=1398078
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Although the symbols formula_19 and formula_18 may appear familiar, their interpretation in the Wheeler–DeWitt equation is substantially different from non-relativistic quantum mechanics. formula_18 is no longer a spatial wave function in the traditional sense of a complex-valued function that is defined on a 3-dimensi...
https://en.wikipedia.org/wiki?curid=1253305
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In the 1970s, as reported in "A Brief History of the Association for Women in Mathematics: The Presidents' Perspectives", by Lenore Blum, "In those years the AMS [American Mathematical Society] was governed by what could only be called an 'old boys network,' closed to all but those in the inner circle." Mary W. Gray ch...
https://en.wikipedia.org/wiki?curid=198822
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Hydrobiologia, "The International Journal of Aquatic Sciences", is a peer-reviewed scientific journal publishing 21 issues per year, for a total of well over 4000 pages per year. "Hydrobiologia" publishes original research, reviews and opinions investigating the biology of freshwater and marine habitats, including the ...
https://en.wikipedia.org/wiki?curid=25613347
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Finally, in addition to improving overall protein integrity, Hsp70 directly inhibits apoptosis. One hallmark of apoptosis is the release of cytochrome c, which then recruits Apaf-1 and dATP/ATP into an apoptosome complex. This complex then cleaves procaspase-9, activating caspase-9 and eventually inducing apoptosis via...
https://en.wikipedia.org/wiki?curid=474345
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Recent studies claim that obesity is a risk factor for hypertension because of activation of the renin–angiotensin system (RAS) in adipose tissue, and also linked renin–angiotensin system with insulin resistance, and claims that anyone can cause the other. Local production of angiotensin II in various tissues, includin...
https://en.wikipedia.org/wiki?curid=23153682
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At the juncture of lipid synthesis and oxidation pathways, ACC presents many clinical possibilities for the production of novel antibiotics and the development of new therapies for diabetes, obesity, and other manifestations of metabolic syndrome. Researchers aim to take advantage of structural differences between bact...
https://en.wikipedia.org/wiki?curid=2339266
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As the polysilicon industry had started to build additional large production capacities during the shortage period, prices dropped as low as $15 per kilogram forcing some producers to suspend production or exit the sector. Prices for silicon stabilized around $20 per kilogram and the booming solar PV market helped to r...
https://en.wikipedia.org/wiki?curid=21150165
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A major formation technique in gangs is through recruitment. Recruitment can be seen in schools, mainly middle and high school, parks, neighborhoods and community centers. Ways that gangs recruit are summarized in four different types: "gangs employ strategies of obligation, coercion, seduction, and subterfuge to attra...
https://en.wikipedia.org/wiki?curid=37879363
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Rapidly growing in rapidly growing markets, are what organizations strive for; but, as we have seen, the penalty is that they are usually net cash users – they require investment. The reason for this is often because the growth is being 'bought' by the high investment, in the reasonable expectation that a high market s...
https://en.wikipedia.org/wiki?curid=1132349
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Since 1949 China has attempted, with mixed success, to organize research and development according to a centralized national plan. The various plans for scientific development that China has adopted since 1957 have been broad — listing topics and areas of priority without going into much detail or attempting to issue t...
https://en.wikipedia.org/wiki?curid=14246598
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A long and complex series of continental collisions known collectively as the Caledonian orogeny began in the Ordovician and continued through the Silurian into Devonian times. The effect in this area was to cause folding and faulting of the existing rock sequence, most particularly within the Welsh Basin, a process wh...
https://en.wikipedia.org/wiki?curid=9406869
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Efforts to understand the interaction between specific xenobiotics and the microbiome have traditionally involved the use of "in vivo" as well as "in vitro" models. Recently, next generation sequencing of genomic DNA obtained from a community of microbes has been used to identify organisms within microbial communities,...
https://en.wikipedia.org/wiki?curid=53368771
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Ames contributed to his field by publishing four textbooks, serving on the editorial staff of the "Astrophysical Journal" and "Harper's Scientific Monthly", delivering Northwestern University's Harris Lectures on "The Constitution of Matter", co-authoring a book, "Theoretical Mechanics", and holding the office of presi...
https://en.wikipedia.org/wiki?curid=3035135
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Pressure Cycling Technology ("PCT"). PCT is a patented, enabling technology platform that uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels (up to 90,000 psi) to safely, conveniently and reproducibly control the actions of molecules in biological samples, e.g., the rupture (lysis) of...
https://en.wikipedia.org/wiki?curid=1637666
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In spite of the system being presented publicly, and its measurements widely reported in the UK, its impact on the art of RDF seems to be strangely subdued. Development was limited until the mid-1930s, when the various British forces began widespread development and deployment of these "high-frequency direction finding...
https://en.wikipedia.org/wiki?curid=820724
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The "Revenge"-class ships (sometimes referred to as the ""Royal Sovereign" class" or the "R class") were designed as slightly smaller, slower, and more heavily protected versions of the preceding s. The design staff, led by Eustace Tennyson d'Eyncourt, the Director of Naval Construction, had been charged by the Board o...
https://en.wikipedia.org/wiki?curid=465646
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A mid-1987 "Personal Computer World" preview of the Archimedes based on the "A500 Development System" expressed enthusiasm about the computer's performance, that it "felt like the fastest computer I have ever used, by a considerable margin", indicating that the system deserved success in the education market and might ...
https://en.wikipedia.org/wiki?curid=63145
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The Wyss Institute for Biologically Inspired Engineering (pronounced "veese") is a cross-disciplinary research institute at Harvard University focused on bridging the gap between academia and industry (translational medicine) by drawing inspiration from nature's design principles to solve challenges in health care and ...
https://en.wikipedia.org/wiki?curid=70740162
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Generally, foot surgery is usually reserved for patients with a walking or ambulatory potential. Foot surgery may also be indicated to assist brace and orthosis fitting and hence promote supported standing. The most common foot deformity in arthrogryposis is club feet or talipes equinovarus. In the early years of life ...
https://en.wikipedia.org/wiki?curid=969023
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Even arguments about the existence of a thing require a certain sharing of a concept, even though its existence in the real world may be disputed. Separating belief from naming and definition also helps to clarify this issue, and show how concepts can be held in common, even in the face of differing beliefs. For instan...
https://en.wikipedia.org/wiki?curid=3200382
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The basis of the chemical periodicity in the periodic table is the electron shell closure at each noble gas (atomic numbers 2, 10, 18, 36, 54, 86, and 118): as any further electrons must enter a new shell with higher energy, closed-shell electron configurations are markedly more stable, hence the inertness of noble gas...
https://en.wikipedia.org/wiki?curid=77473
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One of Davidson’s main collaborators on the book, and the author of several chapters, was fellow Scot, Patrick Manson (1844-1922), who had recently returned to Britain after working in China and the British colony of Hong Kong for more than 20 years. For the next few years the professional paths of the pair would overl...
https://en.wikipedia.org/wiki?curid=65131998
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The McMahon Act, which was signed by Truman on 1 August 1946, and went into effect at midnight on 1 January 1947, ended technical cooperation. Its control of "restricted data" prevented the United States' allies from receiving any information. The remaining scientists were denied access to papers that they had written ...
https://en.wikipedia.org/wiki?curid=41957579
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The extinction event marks a floral turnover as well, although overall, plants suffered minor diversity losses on a global scale as a result of the extinction. Though spore turnovers are observed across the Triassic-Jurassic boundary, the abruptness of this transition and the relative abundances of given spore types bo...
https://en.wikipedia.org/wiki?curid=31188
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Although these 'parameters of grammaticalization' are often linked to the theory, linguists such as Bybee et al. (1994) have acknowledged that independently, they are not essential to grammaticalization. In addition, most are not limited to grammaticalization but can be applied in the wider context of language change. ...
https://en.wikipedia.org/wiki?curid=3169551
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Early records of fundamental aerodynamic concepts date back to the work of Aristotle and Archimedes in the 2nd and 3rd centuries BC, but efforts to develop a quantitative theory of airflow did not begin until the 18th century. In 1726 Isaac Newton became one of the first aerodynamicists in the modern sense when he deve...
https://en.wikipedia.org/wiki?curid=40119871
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