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Like the many other species of the genus "Penicillium", "P. chrysogenum" usually reproduces by forming dry chains of spores (or conidia) from brush-shaped conidiophores. The conidia are typically carried by air currents to new colonisation sites. In "P. chrysogenum", the conidia are blue to blue-green, and the mold sometimes exudes a yellow pigment. However, "P. chrysogenum" cannot be identified based on colour alone. Observations of morphology and microscopic features are needed to confirm its identity and DNA sequencing is essential to distinguish it from closely related species such as "P. rubens". The sexual stage of "P. chrysogenum" was discovered in 2013 by mating cultures in the dark on oatmeal agar supplemented with biotin, after the mating types (MAT1-1 or MAT1-2) of the strains had been determined using PCR amplification.
https://en.wikipedia.org/wiki?curid=28830965
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Bethe's work at Los Alamos included calculating the critical mass and efficiency of uranium-235 and the multiplication of nuclear fission in an exploding atomic bomb. Along with Richard Feynman, he developed a formula for calculating the bomb's explosive yield. After August 1944, when the laboratory was reorganized and reoriented to solve the problem of the implosion of the plutonium bomb, Bethe spent much of his time studying the hydrodynamic aspects of implosion, a job that he continued into 1944. In 1945, he worked on the neutron initiator, and later, on radiation propagation from an exploding atomic bomb. The Trinity nuclear test validated the accuracy of T Division's results. When it was detonated in the New Mexico desert on July 16, 1945, Bethe's immediate concern was for its efficient operation, and not its moral implications. He is reported to have commented: "I am not a philosopher."
https://en.wikipedia.org/wiki?curid=185853
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The Germans made heavy use, in several variants, of an electromechanical rotor machine known as Enigma. Mathematician Marian Rejewski, at Poland's Cipher Bureau, in December 1932 deduced the detailed structure of the German Army Enigma, using mathematics and limited documentation supplied by Captain Gustave Bertrand of French military intelligence acquired from a German clerk. This was the greatest breakthrough in cryptanalysis in a thousand years and more, according to historian David Kahn. Rejewski and his mathematical Cipher Bureau colleagues, Jerzy Różycki and Henryk Zygalski, continued reading Enigma and keeping pace with the evolution of the German Army machine's components and encipherment procedures for some time. As the Poles' resources became strained by the changes being introduced by the Germans, and as war loomed, the Cipher Bureau, on the Polish General Staff's instructions, on 25 July 1939, at Warsaw, initiated French and British intelligence representatives into the secrets of Enigma decryption.
https://en.wikipedia.org/wiki?curid=520066
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Following the government's refusal, a private trust was formed to campaign for the ship's preservation. The "Belfast" Trust was established; its chairman was Rear-Admiral Sir Morgan Morgan-Giles, captain of "Belfast" from January 1961 to July 1962. As Member of Parliament (MP) for Winchester, Morgan-Giles addressed the House of Commons on 8 March 1971. He described "Belfast" as being in "a really wonderful state of preservation" and that saving her for the nation represented a "case of grasping the last opportunity". Among the MPs who spoke in support of Morgan-Giles was Gordon Bagier, MP for Sunderland South, who served as a Royal Marine gunner aboard "Belfast" and was present at both the sinking of "Scharnhorst" and the Normandy landings. Speaking for the government, the Under-secretary for the Navy, Peter Kirk, said that "Belfast" was "one of the most historic ships which the Navy has had in the last 20 years", but that he could not prevent the stripping of the ship's removable equipment, as this was already too far advanced to be halted. He did, however, agree to postpone any decision on the scrapping of "Belfast" to allow the Trust to put together a formal proposal.
https://en.wikipedia.org/wiki?curid=209815
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Shoucheng Zhang (; February 15, 1963 – December 1, 2018) was a Chinese-American physicist who was the JG Jackson and CJ Wood professor of physics at Stanford University. He was a condensed matter theorist known for his work on topological insulators, the quantum Hall effect, the quantum spin Hall effect, spintronics, and high-temperature superconductivity. According to the National Academy of Sciences:He discovered a new state of matter called topological insulator in which electrons can conduct along the edge without dissipation, enabling a new generation of electronic devices with much lower power consumption. For this ground breaking work he received numerous international awards, including the Buckley Prize, the Dirac Medal and Prize, the Europhysics Prize, the Physics Frontiers Prize and the Benjamin Franklin Medal.
https://en.wikipedia.org/wiki?curid=34073210
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Naturally occurring DNA double-strand breaks (DSBs) arise in human cells largely from single-strand breaks induced by various processes including the activity of reactive oxygen species, topoisomerases, and hydrolysis due to thermal fluctuations. In neurons DSBs are induced by a type II topoisomerase as part of the physiologic process of memory formation. DSBs are present in both neurons and astrocytes in the postmortem human hippocampus of AD patients at a higher level than in non-AD individuals. AD is associated with an accumulation of DSBs in neurons and astrocytes in the hippocampus and frontal cortex from early stages onward. DSBs are increased in the vicinity of amyloid plaques in the hippocampus, indicating a potential role for Aβ in DSB accumulation or vice versa. The predominant mechanism for repairing DNA double-strand breaks is non-homologous end joining (NHEJ), a mechanism that utilizes the DNA-dependent protein kinase (DNA-PK) complex. The end joining activity and protein levels of DNA-PK catalytic subunit are significantly lower in AD brains than in normal brains.
https://en.wikipedia.org/wiki?curid=7201415
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The Saturn IB was used between 1973 and 1975 for three crewed Skylab flights, and one Apollo-Soyuz Test Project flight. This final production run did not have alternating black and white S-IB stage tanks, or vertical stripes on the S-IVB aft tank skirt, which were present on the earlier vehicles. Since LC-34 and 37 were inactive by then, these launches utilized Kennedy Space Center's LC-39B. Mobile Launcher Platform No. 1 was modified, adding an elevated platform known as the "milkstool" to accommodate the height differential between the Saturn IB and the much larger Saturn V. This enabled alignment of the Launch Umbilical Tower's access arms to accommodate crew access, fueling, and ground electrical connections for the Apollo spacecraft and S-IVB upper stage. The tower's second stage access arms were modified to service the S-IB first stage.
https://en.wikipedia.org/wiki?curid=551435
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However, despite the potential for the technology to have an impact in made-to-measure and mass customisation of items with ergonomic properties, 3D body scanning has yet to reach an early adopter or early majority stage of innovation diffusion. This in part due to the lack of ergonomic theory relating to how to identify key landmarks on the body morphology. The suitability of 3D body scanning is also context dependent as the measurements taken and the precision of the machine are highly relative to the task in hand rather than being an absolute. Additionally, a key limitation of 3D body scanning has been the upfront cost of the equipment and the required skills by which to collect data and apply it to scientific and technical fields. However, the utilization of depth cameras on recent smartphones helps reduce the cost of 3D scans. One example of this is the recent free face scan app available on the Apple App Store
https://en.wikipedia.org/wiki?curid=53065847
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By 1971, however, Soviet studies determined the need for different types of fighters. The PFI program was supplemented with the "Perspektivnyy Lyogkiy Frontovoy Istrebitel" ("LPFI", or "Advanced Lightweight Tactical Fighter") program; the Soviet fighter force was planned to be approximately 33% PFI and 67% LPFI. PFI and LPFI paralleled the USAF's decision that created the "Lightweight Fighter" program and the General Dynamics F-16 Fighting Falcon and Northrop YF-17. The PFI fighter was assigned to Sukhoi, resulting in the Sukhoi Su-27, while the lightweight fighter went to Mikoyan. Detailed design work on the resultant Mikoyan "Product 9", designated "MiG-29A", began in 1974, with the first flight taking place on 6 October 1977. The pre-production aircraft was first spotted by United States reconnaissance satellites in November of that year; it was dubbed "Ram-L" because it was observed at the Zhukovsky flight test center near the town of Ramenskoye.
https://en.wikipedia.org/wiki?curid=185653
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The effects of climate change on agriculture can result in lower crop yields and nutritional quality due to drought, heat waves and flooding as well as increases in pests and plant diseases. The effects are unevenly distributed across the world and are caused by changes in temperature, precipitation and atmospheric carbon dioxide levels due to global climate change. In 2019, millions were already suffering from food insecurity due to climate change. Further, the predicted decline in global crop production is 2% - 6% with each decade. In 2019 it was predicted that food prices would rise by 80% by 2050. This will likely lead to increased food insecurity, disproportionally affecting poorer communities. A 2021 study estimated that the severity of heatwave and drought impacts on crop production tripled over the last 50 years in Europe – from losses of 2.2% during 1964–1990 to losses of 7.3% in 1991–2015.
https://en.wikipedia.org/wiki?curid=47512577
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Gills usually consist of thin filaments of tissue, branches, or slender tufted processes that have a highly folded surface to increase surface area. The high surface area is crucial to the gas exchange of aquatic organisms as water contains only a small fraction of the dissolved oxygen that air does. A cubic meter of air contains about 250 grams of oxygen at STP. The concentration of oxygen in water is lower than air and it diffuses more slowly. In a litre of freshwater the oxygen content is 8 cm per litre compared to 210 in the same volume of air. Water is 777 times more dense than air and is 100 times more viscous. Oxygen has a diffusion rate in air 10,000 times greater than in water. The use of sac-like lungs to remove oxygen from water would not be efficient enough to sustain life. Rather than using lungs "Gaseous exchange takes place across the surface of highly vascularised gills over which a one-way current of water is kept flowing by a specialised pumping mechanism. The density of the water prevents the gills from collapsing and lying on top of each other, which is what happens when a fish is taken out of water."
https://en.wikipedia.org/wiki?curid=37926134
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Despite the overwhelming evidence that the organism grew on land, Carruthers's interpretation that it was a giant marine alga was challenged just the once, in 1919, when Church suggested that Carruthers had been too quick to rule out the possibility of the fungi. The lack of any characters diagnostic of any extant group made the presentation of a firm hypothesis difficult; the fossil remained an enigmatic mystery and subject of debate. It was not until 2001, after 20 years of research, that Francis Hueber, of Washington's National Museum of Natural History, published a long-awaited paper which attempted to put "Prototaxites" in its place. The paper deduced, based on its morphology, that "Prototaxites" was a fungus.
https://en.wikipedia.org/wiki?curid=10857884
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Ask A Biologist is a pre-kindergarten through high school program dedicated to answering questions from students, their teachers, and parents. The primary focus of the program is to connect students and teachers with working scientists through a question and answer Web e-mail form. The companion website also includes a large collection of free content and activities that can be used inside, as well as outside, of the classroom. The award-winning program has been continuously running for more than 14 years, with the assistance of more than 150 volunteer scientists, faculty, and graduate students in biology and related fields. In 2010 the program released its new website interface and features that became the subject for articles in the journals
https://en.wikipedia.org/wiki?curid=21162294
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The primary reason for housing the two laboratories in the same complex was economic. It saves the citizens of Canada money by only having one facility to operate with a number of shared services also keeping costs down. However, the partnership between these two world leading labs also allows for collaboration and cooperation on established, emerging and re-emerging infectious diseases. Many of the viruses, bacteria and prions studied at CSCHAH are zoonotic, meaning that they can transfer from animals to humans. Co-location of these labs allows scientists to work together on these shared challenges and to take advantage of each other's complementary expertise and unique resources. This model is held in high regard within the international containment laboratory community.
https://en.wikipedia.org/wiki?curid=19298710
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An example for permutation by duplication is the relationship between saposin and swaposin. Saposins are highly conserved glycoproteins, approximately 80 amino acid residues long and forming a four alpha helical structure. They have a nearly identical placement of cysteine residues and glycosylation sites. The cDNA sequence that codes for saposin is called prosaposin. It is a precursor for four cleavage products, the saposins A, B, C, and D. The four saposin domains most likely arose from two tandem duplications of an ancestral gene. This repeat suggests a mechanism for the evolution of the relationship with the plant-specific insert (PSI). The PSI is a domain exclusively found in plants, consisting of approximately 100 residues and found in plant aspartic proteases. It belongs to the saposin-like protein family (SAPLIP) and has the N- and C- termini "swapped", such that the order of helices is 3-4-1-2 compared with saposin, thus leading to the name "swaposin".
https://en.wikipedia.org/wiki?curid=31917729
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The order Polypodiales was first described by Link in 1833. The circumscription of the order has changed over time as ferns have been classified in many different ways (see the review by Christenhusz and Chase, 2014). Smith et al. (2006) carried out the first higher-level pteridophyte classification published in the molecular phylogenetic era. They referred to the ferns (now including horsetails) as monilophytes, dividing them into four groups, with the vast majority of species being placed in a taxon they called "Polypodiopsida". The four-fold grouping has persisted through subsequent systems, despite changes in nomenclature. Polypodiopsida is now used for all ferns ("sensu lato"), with Smith et al.'s group being subclass Polypodiidae. This group, which includes Polypodiales, is also informally known as the leptosporangiate ferns, while the remaining three groups (subclasses) are referred to as eusporangiate ferns. The Polypodiidae have been divided into seven orders, Polypodiales being the largest. The phylogenetic position of Polypodiales in relation to the other orders of Polypodiidae is shown in the following cladogram.
https://en.wikipedia.org/wiki?curid=1291680
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The NASA Spitzer Space Telescope, which detects infrared radiation, discovered a very powerful molecular hydrogen signal from the shock wave between the galaxies. This emission is one of the most turbulent formations of molecular hydrogen ever seen, and the strongest emission originates near the center of the green area in the visible light picture discussed earlier. This phenomenon was discovered by an international team led by scientists at the California Institute of Technology and including scientists from Australia, Germany and China. The detection of molecular hydrogen from the collision was initially unexpected because the hydrogen molecule is very fragile and is easily destroyed in shock waves of the kind expected in Stephan's Quintet. However, one solution is that when a shock front moves through a cloudy medium like the center of the group, millions of smaller shocks are produced in a turbulent layer, and this can allow molecular hydrogen to survive.
https://en.wikipedia.org/wiki?curid=447864
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State- or NGO-sponsored projects can help farmers be more resilient to climate change, such as irrigation infrastructure providing a dependable water source as rains become more erratic. Water catchment systems that collect water during the rainy season to be used during the dry season or periods of drought, can also be used to mitigate the effects of climate change. Some programs, like Asociación de Cooperación para el Desarrollo Rural de Occidente (C.D.R.O.), a Guatemalan program funded by the United States’ government until 2017, focus on agroforestry and weather monitoring systems to help farmers adapt. The organization provided residents with resources to plant new, more adaptable crops to alongside their typical maize to protect the corn from variable temperatures, frost, etc. C.D.R.O. also set up a weather monitoring system to help predict extreme weather events, and would send residents text messages to warn them about periods of frosts, extreme heat, humidity, or drought. Projects focusing on irrigation, water catchment, agroforestry, and weather monitoring can help Central American residents adapt to climate change.
https://en.wikipedia.org/wiki?curid=61503585
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Expression of the three SNAP proteins in mammalian is tissue dependent with α-SNAP (33kD) and γ-SNAP (36kD) expressed throughout the body, and β-SNAP (34kD) primarily found in brain tissues. α-SNAP and β-SNAP share approximately 83% sequence homology and are encoded by NAPA and NAPB on chromosomes 19 and 18, respectively in humans. β-SNAP protein is encoded by the NAPB on chromosome 20. Changes in temporal expression have been observed in rodent models during embryonic development but similar changes in humans is yet to be verified. Expression data in the early years after discovery of the protein group in the 1990s were primarily confirmed though use of Western blott and allowed expression of the mRNA and later cDNA. Use of Immunofluorescent localization showed strong association of the proteins to intracellular membranes including the ER and Golgi bodies as well as vesicles.
https://en.wikipedia.org/wiki?curid=44844593
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The thought experiment involves a pair of particles prepared in what later authors would refer to as an entangled state. Einstein, Podolsky, and Rosen pointed out that, in this state, if the position of the first particle were measured, the result of measuring the position of the second particle could be predicted. If instead the momentum of the first particle were measured, then the result of measuring the momentum of the second particle could be predicted. They argued that no action taken on the first particle could instantaneously affect the other, since this would involve information being transmitted faster than light, which is forbidden by the theory of relativity. They invoked a principle, later known as the "EPR criterion of reality", positing that: "If, without in any way disturbing a system, we can predict with certainty (i.e., with probability equal to unity) the value of a physical quantity, then there exists an element of reality corresponding to that quantity." From this, they inferred that the second particle must have a definite value of both position and of momentum prior to either being measured. But in quantum mechanics these two observables are incompatible and it therefore does not associate simultaneous values for both to any system. Therefore, Einstein, Podolsky, and Rosen concluded that quantum theory did not provide a complete description of reality.
https://en.wikipedia.org/wiki?curid=10296
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The bassoon is a woodwind instrument in the double reed family, which plays in the tenor and bass ranges. It is composed of six pieces, and is usually made of wood. It is known for its distinctive tone color, wide range, versatility, and virtuosity. It is a non-transposing instrument and typically its music is written in the bass and tenor clefs, and sometimes in the treble. There are two forms of modern bassoon: the Buffet (or French) and Heckel (or German) systems. It is typically played while sitting using a seat strap, but can be played while standing if the player has a harness to hold the instrument. Sound is produced by rolling both lips over the reed and blowing direct air pressure to cause the reed to vibrate. Its fingering system can be quite complex when compared to those of other instruments. Appearing in its modern form in the 19th century, the bassoon figures prominently in orchestral, concert band, and chamber music literature, and is occasionally heard in pop, rock, and jazz settings as well. One who plays a bassoon is called a bassoonist.
https://en.wikipedia.org/wiki?curid=4207
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The "Pasilan 2000", the improved version, has been developed with characteristics similar to a rocket launcher. The Pasilan 2000 was a heavy mortar fired from a mobile launcher mounted on a tractor. The shell does not emit constant muzzle flares like Artillery or MBRL. This is ideal for LTTE's camouflage and conceals attacking style. Once a round is fired, forward observers/spies/civilian spotters can correct the fire. The way the tube is installed is similar to the positioning of rocket pods. The length and calibre of the barrel indicate Pasilan 2000 system has common features to the Chinese made Type 82 130mm 30-tube MLRS (introduced by the Palestinian Liberation Army (PLA) in the early 1980s) rather than rail-guided Katyusha variants such as the Qassam Rocket. The warhead weight is 70kg and it is filled with TNT. It had a range of 15-25km. The rocket has since then undergone some modifications. The Pasilan 2000 was more lethal than Baba mortar. But it was not heavily used for ground attacks during the Eelam war 4.
https://en.wikipedia.org/wiki?curid=324499
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Considering the broad-range distribution of "B. ranarum" and its high ubiquity, subcutaneous zygomycosis is not really prevalent. In addition, the fact that infections were only reported at tropical and subtropical regions further limits its prevalence. Currently, the reason why the infections were limited to those regions is not fully understood. However, the low prevalence might be explained by the speculations that the widespread immunity of other species was developed against its infection or the number of the "B. ranarum" strains with pathogenic characteristics is much lower than the saprophytic strains. Its transmission mode has not been fully understood though certain general ideas about its transmission are widely accepted. Ingestion of "B. ranarum" is thought to help disperse the agent through the deposition of feces at a distant place where human and other non-human animals might be exposed. As well, the agent may transmit through traumas or insect bites on skin.
https://en.wikipedia.org/wiki?curid=7041908
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At 24 weeks, significant improvements were found, including accuracy of information processing improved, but a decline was seen in those who remained on benzodiazepines. Further improvements were noted at the 52-week follow-up, indicating ongoing improvements with benzodiazepine abstinence. Younger people on benzodiazepines also experience cognitive deterioration in visual-spatial memory but are not as vulnerable as the elderly to the cognitive effects. Improved reaction times were noted at 52 weeks in elderly patients free from benzodiazepines. This is an important function in the elderly, especially if they drive a car due to the increased risk of road traffic accidents in benzodiazepine users. At the 24-week follow-up, 80% of people had successfully withdrawn from benzodiazepines. Part of the success was attributed to the placebo method used for part of the trial which broke the psychological dependence on benzodiazepines when the elderly patients realised they had completed their gradual reduction several weeks previously and had only been taking placebo tablets. This helped reassure them they could sleep without their pills.
https://en.wikipedia.org/wiki?curid=11683572
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Hybrid automatic repeat request (hybrid ARQ or HARQ) is a combination of high-rate forward error correction (FEC) and automatic repeat request (ARQ) error-control. In standard ARQ, redundant bits are added to data to be transmitted using an error-detecting (ED) code such as a cyclic redundancy check (CRC). Receivers detecting a corrupted message will request a new message from the sender. In Hybrid ARQ, the original data is encoded with an FEC code, and the parity bits are either immediately sent along with the message or only transmitted upon request when a receiver detects an erroneous message. The ED code may be omitted when a code is used that can perform both forward error correction (FEC) in addition to error detection, such as a Reed–Solomon code. The FEC code is chosen to correct an expected subset of all errors that may occur, while the ARQ method is used as a fall-back to correct errors that are uncorrectable using only the redundancy sent in the initial transmission. As a result, hybrid ARQ performs better than ordinary ARQ in poor signal conditions, but in its simplest form this comes at the expense of significantly lower throughput in good signal conditions. There is typically a signal quality cross-over point below which simple hybrid ARQ is better, and above which basic ARQ is better.
https://en.wikipedia.org/wiki?curid=3546973
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"Panellus stipticus" is a saprobic species, and causes a white rot. This is a form of wood decay in which the wood assumes a bleached appearance and where lignin as well as cellulose and hemicellulose is broken down by enzymes secreted by the fungus. Fruit bodies are usually found in tightly overlapping clusters on the sides of hardwood trees, on logs, stumps, and fallen branches. Although most commonly found on dead wood, it can also grow opportunistically in the wounds of living trees. In North America, its preferred hosts are oak, birch, maple, hickory, pecan, and American hornbeam, while in Europe, it is commonly found growing on oak, birch, alder, beech, hazel, chestnut, and ash. It has also been found growing on "Ericia" in North Africa. Although the fungus favors hardwoods, it has been reported to grow on loblolly pine and eastern white pine. Fruiting occurs September through November in Europe, the Canary Islands, and North America, although it may also sometimes be found in the spring. The fruit bodies are long-lasting and may be found year-round. It is an "early-stage" succession fungus, not typically recorded from plantations over 20 years old.
https://en.wikipedia.org/wiki?curid=25648059
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The nucleus of the helium-4 atom is identical with an alpha particle. High-energy electron-scattering experiments show its charge to decrease exponentially from a maximum at a central point, exactly as does the charge density of helium's own electron cloud. This symmetry reflects similar underlying physics: the pair of neutrons and the pair of protons in helium's nucleus obey the same quantum mechanical rules as do helium's pair of electrons (although the nuclear particles are subject to a different nuclear binding potential), so that all these fermions fully occupy 1s orbitals in pairs, none of them possessing orbital angular momentum, and each cancelling the other's intrinsic spin. Adding another of any of these particles would require angular momentum and would release substantially less energy (in fact, no nucleus with five nucleons is stable). This arrangement is thus energetically extremely stable for all these particles, and this stability accounts for many crucial facts regarding helium in nature.
https://en.wikipedia.org/wiki?curid=13256
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The nucleus of the helium-4 atom is identical to an alpha particle. High-energy electron-scattering experiments show its charge to decrease exponentially from a maximum at a central point, exactly as does the charge density of helium's own electron cloud. This symmetry reflects similar underlying physics: the pair of neutrons and the pair of protons in helium's nucleus obey the same quantum mechanical rules as do helium's pair of electrons (although the nuclear particles are subject to a different nuclear binding potential), so that all these fermions fully occupy 1s orbitals in pairs, none of them possessing orbital angular momentum, and each canceling the other's intrinsic spin. Adding another of any of these particles would require angular momentum, and would release substantially less energy (in fact, no nucleus with five nucleons is stable). This arrangement is thus energetically extremely stable for all these particles, and this stability accounts for many crucial facts regarding helium in nature.
https://en.wikipedia.org/wiki?curid=1012996
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Prefix/postfix notation is especially popular for its innate ability to express the intended order of operations without the need for parentheses and other precedence rules, as are usually employed with infix notation. Instead, the notation uniquely indicates which operator to evaluate first. The operators are assumed to have a fixed arity each, and all necessary operands are assumed to be explicitly given. A valid prefix expression always starts with an operator and ends with an operand. Evaluation can either proceed from left to right, or in the opposite direction. Starting at the left, the input string, consisting of tokens denoting operators or operands, is pushed token for token on a stack, until the top entries of the stack contain the number of operands that fits to the top most operator (immediately beneath). This group of tokens at the stacktop (the last stacked operator and the according number of operands) is replaced by the result of executing the operator on these/this operand(s). Then the processing of the input continues in this manner. The rightmost operand in a valid prefix expression thus empties the stack, except for the result of evaluating the whole expression. When starting at the right, the pushing of tokens is performed similarly, just the evaluation is triggered by an operator, finding the appropriate number of operands that fits its arity already at the stacktop. Now the leftmost token of a valid prefix expression must be an operator, fitting to the number of operands in the stack, which again yields the result. As can be seen from the description, a push-down store with no capability of arbitrary stack inspection suffices to implement this parsing.
https://en.wikipedia.org/wiki?curid=25056
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A particular concern in design of electrical substations is earth potential rise. When very large fault currents are injected into the earth, the area around the point of injection may rise to a high potential with respect to points distant from it. This is due to the limited finite conductivity of the layers of soil in the earth of the substation. The gradient of the voltage (the change in voltage across the distance to the injection point) may be so high that two points on the ground may be at significantly different potentials. This gradient creates a hazard to anyone standing on the earth in an area of the electrical substation that is insufficiently insulated from ground. Pipes, rails, or communication wires entering a substation may see different ground potentials inside and outside the substation, creating a dangerous touch voltage for unsuspecting persons who might touch those pipes, rails, or wires. This problem is alleviated by creating a low-impedance equipotential bonding plane installed in accordance with IEEE 80, within the substation. This plane eliminates voltage gradients and ensures that any fault is cleared within three voltage cycles.
https://en.wikipedia.org/wiki?curid=41215
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In order to protect soldiers from hearing loss, the U.S. Army adhered to the Military Standard (MIL-STD) 1474, which defined the maximum noise levels permitted to be produced by military systems. However, human volunteer studies demonstrated that the standard used since 1997, the MIL-STD-1474D, overestimated the hazard associated with impulse noise exposure. The subsequent overprotection of the ears based on inaccurate evaluations of hearing loss risk was believed to potentially hamper verbal communication between military personnel on the battlefield and reduce situational awareness. The AHAAH was developed to more accurately assess the hazard to the human ear from impulse noise by incorporating the acoustic and physiological characteristics of the ear in its analysis, which were not accounted for in previous metrics. The AHAAH was eventually used in 2015 to completely revise the MIL-STD-1474E and establish a new standard known as the MIL-STD-1474E.
https://en.wikipedia.org/wiki?curid=57869905
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NASA programs previously used pencils (for example a 1965 order of mechanical pencils) but because of the substantial dangers that broken pencil tips and graphite dust pose to electronics in zero gravity, the flammable nature of wood present in pencils, and the inadequate quality documentation produced by non-permanent or smeared recordkeeping, a better solution was needed. Russian cosmonauts used pencils, and grease pencils on plastic slates until also adopting a space pen in 1969 with a purchase of 100 units for use on all future missions. NASA never approached Paul Fisher to develop a pen, nor did Fisher receive any government funding for the pen's development. Fisher invented it independently and then, in 1965, asked NASA to try it. After extensive testing, NASA decided to use the pens in future Apollo missions. Subsequently, in 1967 it was reported that NASA purchased approximately 400 pens for $2.95 apiece (equivalent to $ each in ).
https://en.wikipedia.org/wiki?curid=1195876
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The first implementation of an interactive ray tracer was the LINKS-1 Computer Graphics System built in 1982 at Osaka University's School of Engineering, by professors Ohmura Kouichi, Shirakawa Isao and Kawata Toru with 50 students. It was a massively parallel processing computer system with 514 microprocessors (257 Zilog Z8001s and 257 iAPX 86s), used for rendering realistic 3D computer graphics with high-speed ray tracing. According to the Information Processing Society of Japan: "The core of 3D image rendering is calculating the luminance of each pixel making up a rendered surface from the given viewpoint, light source, and object position. The LINKS-1 system was developed to realize an image rendering methodology in which each pixel could be parallel processed independently using ray tracing. By developing a new software methodology specifically for high-speed image rendering, LINKS-1 was able to rapidly render highly realistic images." It was used to create an early 3D planetarium-like video of the heavens made completely with computer graphics. The video was presented at the Fujitsu pavilion at the 1985 International Exposition in Tsukuba." It was the second system to do so after the Evans & Sutherland Digistar in 1982. The LINKS-1 was reported to be the world's most powerful computer in 1984.
https://en.wikipedia.org/wiki?curid=26000
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For the purposes of illustration I have employed only outline figures, for had either shading or colouring been introduced it might be supposed that the effect was wholly or in part due to these circumstances, whereas by leaving them out of consideration no room is left to doubt that the entire effect of relief is owing to the simultaneous perception of the two monocular projections, one on each retina. But if it be required to obtain the most faithful resemblances of real objects, shadowing and colouring may properly be employed to heighten the effects. Careful attention would enable an artist to draw and paint the two component pictures, so as to present to the mind of the observer, in the resultant perception, perfect identity with the object represented. Flowers, crystals, busts, vases, instruments of various kinds, &c., might thus be represented so as not to be distinguished by sight from the real objects themselves.
https://en.wikipedia.org/wiki?curid=201460
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Regional heterothermy describes organisms that are able to maintain different temperature "zones" in different regions of the body. This usually occurs in the limbs, and is made possible through the use of counter-current heat exchangers, such as the rete mirabile found in tuna and certain birds. These exchangers equalize the temperature between hot arterial blood going out to the extremities and cold venous blood coming back, thus reducing heat loss. Penguins and many arctic birds use these exchangers to keep their feet at roughly the same temperature as the surrounding ice. This keeps the birds from getting stuck on an ice sheet. Other animals, like the leatherback sea turtle, use the heat exchangers to gather, and retain heat generated by their muscular flippers. There are even some insects which possess this mechanism (see insect thermoregulation), the best-known example being bumblebees, which exhibit counter-current heat exchange at the point of constriction between the mesosoma ("thorax") and metasoma ("abdomen"); heat is retained in the thorax and lost from the abdomen. Using a very similar mechanism, the internal temperature of a honeybee's thorax can exceed 45 °C while in flight.
https://en.wikipedia.org/wiki?curid=2107349
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Narlikar has received many national and international awards and honorary doctorates. India's second-highest civilian honour, Padma Vibhushan, was awarded to him in 2004 for his research work. Prior to this, in 1965, he was conferred Padma Bhushan. He was awarded 'Rashtra Bhushan' in 1981 by FIE Foundation, Ichalkaranji. He received Maharashtra Bhushan Award for the year 2010. He is a recipient of Bhatnagar Award, M.P. Birla Award, and the Prix Jules Janssen of the Société astronomique de France (French Astronomical Society). He is an Associate of the Royal Astronomical Society of London, and a Fellow of the three Indian National Science Academies and the Third World Academy of Sciences. Apart from his scientific research, Narlikar has been well known as a communicator of science through his books, articles, and radio & television programs. For these efforts, he was honoured in 1996 by UNESCO with the Kalinga Prize. He was featured on Carl Sagan's TV show "" in the late 1980s. In 1989, he received the Atmaram Award by Central Hindi Directorate. He received the Indira Gandhi Award of the Indian National Science Academy in 1990. He also served on the Physical Sciences jury for the Infosys Prize in 2009. In 2014, he received a Sahitya Akademi Award for his autobiography in Marathi, "Chaar Nagarantale Maze Vishwa". He presided over the 94th Akhil Bharatiya Marathi Sahitya Sammelan held at Nashik in January 2021.
https://en.wikipedia.org/wiki?curid=2251669
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Six countries in the Middle East and North Africa region are on target to meet goals for reducing underweight children by 2015, and 12 countries have prevalence rates below 10%. However, the nutrition of children in the region as a whole has degraded for the past ten years due to the increasing portion of underweight children in three populous nations – Iraq, Sudan, and Yemen. Forty six percent of all children in Yemen are underweight, a percentage that has worsened by 4% since 1990. In Yemen, 53% of children under five are stunted and 32% are born at low birth weight. Sudan has an underweight prevalence of 41%, and the highest proportion of wasted children in the region at 16%. One percent of households in Sudan consume iodized salt. Iraq has also seen an increase in child underweight since 1990. Djibouti, Jordan, the Occupied Palestinian Territory (OPT), Oman, the Syrian Arab Republic and Tunisia are all projected to meet minimum nutrition goals, with OPT, Syrian AR, and Tunisia the fastest improving regions. This region demonstrates that undernutrition does not always improve with economic prosperity, where the United Arab Emirates, for example, despite being a wealthy nation, has similar child death rates due to malnutrition to those seen in Yemen.
https://en.wikipedia.org/wiki?curid=93827
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A renewed interest in the issues of reconstructed pronunciation arose during the 19th century. On the one hand, the new science of historical linguistics, based on the method of comparative reconstruction, took a vivid interest in Greek. It soon established beyond any doubt that Greek was descended in parallel with many other languages from the common source of the Indo-European proto-language. This had important consequences for how its phonological system must be reconstructed. At the same time, continued work in philology and archeology was bringing to light an ever-growing corpus of non-standard, non-literary and non-classical Greek writings, e.g. inscriptions and later also papyri. These added considerably to what could be known about the development of the language. On the other hand, there was a revival of academic life in Greece after the establishment of the Greek state in 1830, and scholars in Greece were at first reluctant to accept the seemingly foreign idea that Greek should have been pronounced so differently from what they knew.
https://en.wikipedia.org/wiki?curid=3110015
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Lukits began his professional career as an illustrator while still in his teens. He was a still life painter, muralist and founder of the Lukits Academy of Fine Arts in Los Angeles for more than sixty years. He had the reputation of a craftsman who made his own paints from raw pigments, constructed brushes and palettes, and designed and carved frames. Lukits was responsible for keeping the "Beaux-Arts" methods of the French academic system alive in the western United States, and several of his students went on to prominent careers. His works are displayed in many public collections. He was a member of a number of professional art organizations and won many awards in competitions. Lukits has been the subject of a number of solo museum exhibitions since his death, and his work has been included in a number of other museum exhibitions devoted to Tonalism and California and American Impressionism.
https://en.wikipedia.org/wiki?curid=12370321
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Passing reference to embryological notions also appear in the Qur'an (22:5), where the development of the embryo proceeds in four stages from drop, to a blood clot, to a partially developed stage, to a fully developed child. The notion of clay turning into flesh is seen by some as analogous to a text by Theodoret that describes the same process. The four stages of development in the Qur'an are similar to the four stages of embryological development as described by Galen. In the early 6th century, Sergius of Reshaina devoted himself to the translation of Greek medical texts into Syriac and became the most important figure in this process. Included in his translations were the relevant embryological texts of Galen. Anurshirvan founded a medical school in the southern Mesopotamian city of Gundeshapur, known as the Academy of Gondishapur, which also acted as a medium for the transmission, reception, and development of notions from Greek medicine. These factors helped the transmission of Greek notions on embryology, such as found in Galen, to enter into the Arabian milieu. Very similar embryonic descriptions also appear in the Syriac Jacob of Serugh's letter to the Archdeacon Mar Julian.
https://en.wikipedia.org/wiki?curid=162717
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Unexpected rain on Saturday meant that the grid was decided entirely by times from Friday's session. Pirelli's soft qualifying tires caught Goodyear off guard, and the Italian manufacturer put five of its teams in the top ten positions, including Jean Alesi, who was fourth in a Tyrrell. In a surprise move, team manager Ken Tyrrell had signed with Pirelli two days before the race, after 18 years with Goodyear. Gerhard Berger's pole-winning McLaren was the only car in the first two rows sporting Goodyears. Pierluigi Martini put Minardi on the front row for the only time in the team's history, less than seven-hundredths off Berger's pole time. In addition, Andrea de Cesaris (Scuderia Italia), Olivier Grouillard (Osella) and Roberto Moreno (EuroBrun) all scored what proved to be their team's best grid position of the year. Ayrton Senna could only manage fifth, while Alain Prost, in his first race for Ferrari, was seventh. Philippe Alliot was excluded when a mechanic worked on the car outside of the pit area during Friday's practice.
https://en.wikipedia.org/wiki?curid=1123069
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To minimize total error, gradient descent can be used to change each weight in proportion to its derivative with respect to the error, provided the non-linear activation functions are differentiable. The standard method is called "backpropagation through time" or BPTT, a generalization of back-propagation for feedforward networks. A more computationally expensive online variant is called "Real-Time Recurrent Learning" or RTRL. Unlike BPTT this algorithm is "local in time but not local in space". An online hybrid between BPTT and RTRL with intermediate complexity exists, with variants for continuous time. A major problem with gradient descent for standard RNN architectures is that error gradients vanish exponentially quickly with the size of the time lag between important events. The Long short-term memory architecture overcomes these problems.
https://en.wikipedia.org/wiki?curid=28016652
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The SH09 adopted several modern features. Its airframe is entirely composed of carbon composite materials; it employs a shrouded fenestron tail rotor and a high-visibility cockpit. The carbon composite construction allowed a relatively low empty weight. According to Mathias Senes, Marenco's chief commercial officer: "There’s no other material today that brings the benefits of rigidity, strength, and light weight". Stucki approached his design from a pilot's perspective, attempting to improve ergonomics, comfort, and operator requirements. It possesses excellent hot and high performance, lengthy flight endurance, a low noise signature, and has relatively smooth handling.
https://en.wikipedia.org/wiki?curid=41128903
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In 1906, Erlanger accepted a position as the first chair of physiology at the University of Wisconsin in Madison. In 1910, he left to take a position as professor at Washington University in St. Louis; the St. Louis position offered Erlanger more funding for his projects. Herbert Spencer Gasser, Erlanger's former student at Wisconsin, joined Erlanger's laboratory soon after the move. During World War I, the pair contributed to the research effort examining the effects of shock. As part of this work, Erlanger was able to produce heart block in an animal model by clamping the bundle of His and tightening it. Together, they managed to amplify the action potential of a bullfrog sciatic nerve in 1922 and published the results in the "American Journal of Physiology". It is uncertain why the pair had such a sudden shift in interest to neuroscience, as Erlanger was already widely respected in the cardiology field.
https://en.wikipedia.org/wiki?curid=779501
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Although the long-term goal of the company is to mine asteroids, its initial plans call for developing a market for small (30–50 kg) cost-reduced space telescopes for Earth observation and astronomy. These spacecraft would employ a laser-optical system for ground communications, reducing payload bulk and mass compared to conventional RF antennas. The deployment of such orbital telescopes was envisioned as the first step forward in the company's asteroid mining ambitions. The same telescope satellite capabilities that Planetary Resources hope to sell to customers could be used to survey and intensively examine near-Earth asteroids.
https://en.wikipedia.org/wiki?curid=35554525
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The VEP was created in 1992 as a collaboration between the UIC Biomedical Visualization Laboratory, directed by Michael Doyle, and the Human Developmental Anatomy Center at the National Museum of Health and Medicine (NMHM), directed by Adrianne Noe. Doyle had been appointed to the oversight committee of the Visible Human Project at the National Library of Medicine, but it would be several years before that data would become available. Looking for other sources of high-resolution volume data of human anatomical structure, he came across the Carnegie Collection of Human Embryology, housed at the NMHM. During a sabbatical working on methods for magnetic resonance microscopy (MRM) in the laboratory of Paul Lauterbur, 2003 Nobel Laureate, Dr. Doyle created a plan for the VEP and worked with Dr. Noe to recruit a large group of prominent researchers to join as initial collaborators.
https://en.wikipedia.org/wiki?curid=70238111
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His extensive travels through most of the major centres of Europe provided him with an unparalleled insight on ancient, Renaissance and more recent architecture, though his poor opinion of many of the more recent buildings he saw, even in Rome and Paris, combined with the overwhelming impact of ancient Greek structures, triggered a significant shift in his architectural tastes. Whereas his earlier designs had been in the conventional French Neo-Classical idiom of the time, influenced by George Dance the Younger and John Soane, most of the classical-style buildings he designed as a professional architect were firmly rooted in the Greek Revival. Unlike some of his contemporaries he did not visit Turkey. His knowledge of its ancient buildings, which were crucial to his designs in the 1820s such as the British Museum, was derived from publications such as "Ionian Antiquities" of 1769 by Richard Chandler, William Pars and Nicholas Revett.
https://en.wikipedia.org/wiki?curid=1484094
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In "Macroneuropteris", each individual leaflet or pinnule of the compound frond were also notably large. In fact, the species " M. scheuchzeri's" pinnules were the largest of any seed plant of the Carboniferous Period. Individual pinnules are typically lanceolate with a round base. They have been found to be as long as 12 cm. These individual leaflets are often found fossilized by themselves separated from the frond. They have been inferred by some to be deciduous. In the famous Mazon Creek Fossil Beds of Illinois, these leaflets are one of the most commonly found plant fossils. The leaves have thick cuticles, sunken stomata, dense trichomes, and large hair-like structures. These foliar characteristics combined with the spiny stem structure where the leaflets drop, and the potential deciduous nature have led to many authors suggesting a xeromorphic tendency in the tree. Such adaptations may have allowed the genus to dominate the late Carboniferous landscape as other plants like Lepidodendrales steadily declined.
https://en.wikipedia.org/wiki?curid=43272653
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The McConkey and Drake (2006) study is unique because it was one of the first attempts to model a density-dependent threshold relationship that described ecological extinction. They studied a seed dispersal interaction between flying foxes and trees with large seeds on the tropical Pacific Islands. Insular flying foxes ("Pteropus tonganus)", are considered to be keystone species because they are the only seed dispersers that can carry large seeds long distances. The host-pathogen model by Janzen and Connell suggests that survivorship of seeds in the tropics greatly increases the further away from the parent tree it lands, and that trees require this dispersal in order to avoid extinction. In the pathogen latent environment of the tropics, seed dispersal only becomes more paramount to species survival. As hypothesized, McConkey and Drake found a threshold relationship between the Flying Fox Index (FFI) and the median proportion of seeds carried over five meters. Below the threshold of abundance seed dispersal was insignificant and independent of flying fox abundance; however, above the threshold, dispersal positively correlated with increased flying fox abundance (as measured by the FFI). Although they did not directly prove the cause for this relationship, McConkey and Drake proposed a behavioral mechanism. Flying foxes are known to be territorial, and in the absence of competition a flying fox will eat within one tree, effectively dropping the seeds right below it. Alternatively, if there is a high density of flying foxes feeding at one time (abundance above the threshold density) then aggressive behavior, such as stealing fruit from another individual's territory, will lead to longer average seed dispersal. In this way the seed dispersing flying fox has a disproportional effect on the overall community structure in comparison to their relative biomass. Modeling the effect of ecological extinction on communities is the first step to applying this framework into conservation work.
https://en.wikipedia.org/wiki?curid=11409359
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Deinosuchus () is an extinct genus of alligatoroid crocodilian, related to modern alligators and caimans, that lived 82 to 73 million years ago (Ma), during the late Cretaceous period. The name translates as "terrible crocodile" and is derived from the Greek "deinos" (δεινός), "terrible", and "soukhos" (σοῦχος), "crocodile". The first remains were discovered in North Carolina (United States) in the 1850s; the genus was named and described in 1909. Additional fragments were discovered in the 1940s and were later incorporated into an influential, though inaccurate, skull reconstruction at the American Museum of Natural History. Knowledge of "Deinosuchus" remains incomplete, but better cranial material found in recent years has expanded scientific understanding of this massive predator.
https://en.wikipedia.org/wiki?curid=1319795
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Studies have demonstrated correlations between increased levels of allelochemicals in target plants and the presence of mycorrhizal networks. These studies strongly suggest that mycorrhizal networks increase the transfer of allelopathic chemicals and expand the range, called the bio-active zone, in which they can disperse and maintain their function. Furthermore, studies indicate increased bio-active zones aid in the effectiveness of the allelochemicals because these infochemicals cannot travel very far without a mycorrhizal network. There was greater accumulation of allelochemicals, such as thiopenes and the herbicide imazamox, in target plants connected to a supplier plant via a mycorrhizal network than without that connection, supporting the conclusion that the mycorrhizal network increased the bio-active zone of the allelochemical. Allelopathic chemicals have also been demonstrated to inhibit target plant growth when target and supplier are connected via AM networks. The black walnut is one of the earliest studied examples of allelopathy and produces juglone, which inhibits growth and water uptake in neighboring plants. In studies of juglone in black walnuts and their target species, the presence of mycorrhizal networks caused target plants to exhibit reduced growth by increasing the transfer of the infochemical. Spotted knapweed, an allelopathic invasive species, provides further evidence of the ability of mycorrhizal networks to contribute to the transfer of allelochemicals. Spotted knapweed can alter which plant species a certain AM fungus prefers to connect to, changing the structure of the network so that the invasive plant shares a network with its target. These and other studies provide evidence that mycorrhizal networks can facilitate the effects on plant behavior caused by allelochemicals.
https://en.wikipedia.org/wiki?curid=38946634
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Additionally, the United States Marine Corps maintains three active (1st, 2nd, & 5th) and three reserve (3rd, 4th & 6th) ANGLICO units. ANGLICO members are temporarily assigned to combat units of the United States and foreign nations that lack inherent fire support capability, such as naval gunfire. The ships equipped with the large caliber guns of the early and middle of the 20th century have all been decommissioned. The last battleship, , was decommissioned in 31 March 1992, leaving no naval guns larger than on any active warship in the world. The aircraft carrier and sea to land missile have been used instead. The remaining naval artillery typically has more advanced targeting systems than the older large-caliber artillery.
https://en.wikipedia.org/wiki?curid=511891
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By 2014 more than 75% of Canadian Prairies' cropland had adopted "conservation tillage" and more than 50% had adopted no until. Twenty-five countries pledged to adopt the practice at the December 2015 Paris climate talks. In California multiple Resource Conservation Districts (RCDs) support local partnerships to develop and implement carbon farming, In 2015 the agency that administers California's carbon-credit exchange began granting credits to farmers who compost grazing lands. In 2016 Chevrolet partnered with the US Department of Agriculture (USDA) to purchase 40,000 carbon credits from ranchers on 11,000 no-till acres. The transaction equates to removing 5,000 cars from the road and was the largest to date in the US. In 2017 multiple US states passed legislation in support of carbon farming and soil health.
https://en.wikipedia.org/wiki?curid=57257793
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"Trout" was next ordered to plant naval mines in Api Passage, off the northwest coast of Borneo. She got underway on 22 March 1943 and on 4 April, while en route from Balabac Strait to Miri, fired a spread of three torpedoes at a naval auxiliary. One hit the target amidships, raising a plume of water into the air, but the warhead did not explode. "Trout" fired a fourth torpedo but the ship saw its wake, turned, and dodged it. The next day, "Trout" launched three torpedoes at another ship with no results. She planted 23 naval mines in Api Passage on 7 and 8 April and then began patrolling the Singapore trade route. On 19 April, she launched four torpedoes at a freighter but scored no hits. Later in the day she fired a spread of three torpedoes at a tanker and missed. "Trout" sighted two trawlers on 23 April and battle surfaced. Her deck guns soon stopped the first ship dead in the water and set it on fire; they then turned the second one into a burning wreck. Since there was only one torpedo remaining, the submarine headed for Fremantle, where she arrived on 3 May 1943.
https://en.wikipedia.org/wiki?curid=430381
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After the so-called 'blue bloc' (a coalition of conservative and economic liberal parties) had lost both the 1994 and 1998 general elections the main centre-right party, Venstre decided in 1999 under the leadership of Anders Fogh Rasmussen to fundamentally change its strategy. In essence, Venstre largely gave up convincing voters about classical liberal positions and instead embraced large parts of the Social Democrats' policies, especially on welfare with important exceptions such as the "". This caused a deviation from several parts of Venstre's ideological basis including Fogh repudiating many of the views expressed in his own 1993 book "From Social State to Minimal State" in which he had argued for limited government and in favour of free markets.
https://en.wikipedia.org/wiki?curid=26894340
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To investigate enzymatic activity as opposed to total protein, activity-based reagents have been developed to label the enzymatically active form of proteins (see Activity-based proteomics). For example, serine hydrolase- and cysteine protease-inhibitors have been converted to suicide inhibitors. This strategy enhances the ability to selectively analyze low abundance constituents through direct targeting. Enzyme activity can also be monitored through converted substrate. Identification of enzyme substrates is a problem of significant difficulty in proteomics and is vital to the understanding of signal transduction pathways in cells. A method that has been developed uses "analog-sensitive" kinases to label substrates using an unnatural ATP analog, facilitating visualization and identification through a unique handle.
https://en.wikipedia.org/wiki?curid=1686272
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Randall is currently a professor at Harvard University in Cambridge, Massachusetts, focusing on particle physics and cosmology. She stays current through her research into the nature of matter's most basic elements, and the forces that govern these most basic elements. Randall's experiences, which qualify her as an authority on the subject of the book, are her original "contributions in a wide variety of physics studies, including cosmological inflation, supersymmetry, grand unified theories, and aspects of string theory". "As of last autumn, she was the most cited theoretical physicist in the world during the previous five years." In addition her most recent work involved extra dimensions.
https://en.wikipedia.org/wiki?curid=2808506
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Behavioural genetics uses genetically informative designs to understand the nature and origins of individual differences in behavior. In focusing on the causes of individual differences, behavioral genetics is distinct from evolutionary psychology, which tends to focus on human universals. Behavioral genetics has thus been associated strongly with the diathesis stress model of psychopathology as well as the nature/nurture debate. Behavioral genetics research was pioneered by Francis Galton and his seminal work in family studies and twin studies after falling out of favor during the eugenics movement during the first part of the 20th century up until World War II. A resurgence of behavioral genetics research began in the 1960s and rose into prominence in the 1980s and beyond. During this time twin study and adoption studies were conducted on a wide array of behavioral traits, including personality, cognitive ability, psychiatric illness, medical illness, and many others. The general conclusion of this large body of work is that every behavioral and medical trait, and indeed measures of the environment is heritable to some moderate degree. Taking advantage of the Human Genome Project more recent work in behavioral genetics uses recent technologies in array-based genotyping, genome sequencing, and other omics to measure genetic variants directly. These genetic variants can then be tested for association with behavioral traits and disorders, for example through genome-wide association studies. This approach to understanding the genetic influences on behavior have seen recent successes in, for example, schizophrenia. Psychiatric genetics is a subfield of behavioral genetics.
https://en.wikipedia.org/wiki?curid=26277853
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In particular, doubly labeled water (DLW) can be used for a method to measure the average daily metabolic rate of an organism over a period of time (often also called the Field metabolic rate, or FMR, in non-human animals). This is done by administering a dose of DLW, then measuring the elimination rates of deuterium and oxygen-18 in the subject over time (through regular sampling of heavy isotope concentrations in body water, by sampling saliva, urine, or blood). At least two samples are required: an initial sample (after the isotopes have reached equilibrium in the body), and a second sample some time later. The time between these samples depends on the size of the animal. In small animals, the period may be as short as 24 hours; in larger animals (such as adult humans), the period may be as long as 14 days.
https://en.wikipedia.org/wiki?curid=4680330
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Those reporting to the superintendent include the Dean of the Faculty and Commandant of Cadets, each of whom typically holds the rank of brigadier general, as well as the Director of Athletics, the Commander of the 10th Air Base Wing and the Commander of the Prep School, each of whom typically holds the rank of colonel. The 10th Air Base Wing provides all base support functions that exist at other air force bases, including civil engineering, communications, medical support, personnel, administration, security and base services. The Preparatory School provides an academic, athletic and military program for qualified young men and women who may need certain additional preparation prior to acceptance to the Academy. All flying programs at the Academy are run by the 306th Flying Training Group, which reports to the Air Education and Training Command, ensuring uniformity of flight training with the rest of the Air Force.
https://en.wikipedia.org/wiki?curid=77587
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Alumni in the sciences include Charles Geschke, co-founder and chairman of Adobe Systems; Stephanie Kwolek, inventor of Kevlar; James Gosling, creator of the Java programming language, Andy Bechtolsheim, co-founder of Sun Microsystems; David Kelley, co-founder of IDEO; George Pake, founder of Xerox PARC; Marc Ewing, co-founder of Red Hat; Jim Levy, founding CEO of Activision; billionaire hedge fund investor and owner of the Carolina Panthers of the National Football League David Tepper; Scott Fahlman, creator of the emoticon; Chris Messina, creator of the hashtag; tech executive and entrepreneur Kai-Fu Lee; and astronauts Edgar Mitchell (Apollo 14) and Judith Resnik, who perished in the Space Shuttle "Challenger" disaster. John Forbes Nash, a 1948 graduate and winner of the 1994 Nobel Memorial Prize in Economics, was the subject of the book and subsequent film "A Beautiful Mind". Alan Perlis, a 1943 graduate, was a pioneer in programming languages and recipient of the first Turing Award.
https://en.wikipedia.org/wiki?curid=48093
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Due to size and weight constraints, common CubeSats flying in LEO with body-mounted solar panels have generated less than 10 W. Missions with higher power requirements can make use of attitude control to ensure the solar panels remain in their most effective orientation toward the Sun, and further power needs can be met through the addition and orientation of deployable solar arrays, which can be unfolded to a substantially larger area on-orbit. Recent innovations include additional spring-loaded solar arrays that deploy as soon as the satellite is released, as well as arrays that feature thermal knife mechanisms that would deploy the panels when commanded. CubeSats may not be powered between launch and deployment, and must feature a remove-before-flight pin which cuts all power to prevent operation during loading into the P-POD. Additionally, a deployment switch is actuated while the craft is loaded into a P-POD, cutting power to the spacecraft and is deactivated after exiting the P-POD.
https://en.wikipedia.org/wiki?curid=641656
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Norepinephrine has higher affinity for the α receptor than has epinephrine, and therefore relates less to the latter's functions. Nonselective α agonists include the antihypertensive drug clonidine, which can be used to lower blood pressure and to reduce hot flashes associated with menopause. Clonidine has also been successfully used in indications that exceed what would be expected from a simple blood-pressure lowering drug: it has recently shown positive results in children with ADHD who have tics resulting from the treatment with a CNS stimulant drug, such as Adderall XR or methylphenidate; clonidine also helps alleviate symptoms of opioid withdrawal. The hypotensive effect of clonidine was initially attributed through its agonist action on presynaptic α receptors, which act as a down-regulator on the amount of norepinephrine released in the synaptic cleft, an example of autoreceptor. However, it is now known that clonidine binds to imidazoline receptors with a much greater affinity than α receptors, which would account for its applications outside the field of hypertension alone. Imidazoline receptors occur in the nucleus tractus solitarii and also the centrolateral medulla. Clonidine is now thought to decrease blood pressure via this central mechanism. Other nonselective agonists include dexmedetomidine, lofexidine (another antihypertensive), TDIQ (partial agonist), tizanidine (in spasms, cramping) and xylazine. Xylazine has veterinary use.
https://en.wikipedia.org/wiki?curid=5023305
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In behavioral genetics, the Scarr–Rowe effect, also known as the Scarr–Rowe hypothesis, refers to the proposed moderating effect of low socioeconomic status on the heritability of children's IQ. According to this hypothesis, lower socioeconomic status and greater exposure to social disadvantage during childhood leads to a decrease in the heritability of IQ, as compared to children raised in more advantaged environments. It is considered an example of gene–environment interaction. This hypothesized effect was first proposed by Sandra Scarr, who found support for it in a 1971 study of twins in Philadelphia, and these results were replicated by David C. Rowe in 1999. Since then, similar results have been replicated numerous times, though not all replication studies have yielded positive results. A 2015 meta-analysis found that the effect was predominant in the United States while less evident in societies with robust child welfare systems.
https://en.wikipedia.org/wiki?curid=60672443
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The surgical treatment for velopalatal insufficiency may cause obstructive sleep apnea syndrome. When velopalatal insufficiency is present, air leaks into the nasopharynx even when the soft palate should close off the nose. A simple test for this condition can be made by placing a tiny mirror on the nose, and asking the subject to say "P". This p sound, a plosive, is normally produced with the nasal airway closes off – all air comes out of the pursed lips, none from the nose. If it is impossible to say the sound without fogging a nasal mirror, there is an air leak – reasonable evidence of poor palatal closure. Speech is often unclear due to inability to pronounce certain sounds. One of the surgical treatments for velopalatal insufficiency involves tailoring the tissue from the back of the throat and using it to purposefully cause partial obstruction of the opening of the nasopharynx. This may actually "cause" OSA syndrome in susceptible individuals, particularly in the days following surgery, when swelling occurs (see below: Special Situation: Anesthesia and Surgery).
https://en.wikipedia.org/wiki?curid=1976353
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MgB (B=Si, Ge, Sn) compounds and their solid solutions are good thermoelectric materials and their ZT values are comparable with those of established materials. The appropriate production methods are based on direct co-melting, but mechanical alloying has also been used. During synthesis, magnesium losses due to evaporation and segregation of components (especially for MgSn) need to be taken into account. Directed crystallization methods can produce single crystals of MgSi, but they intrinsically have n-type conductivity, and doping, e.g. with Sn, Ga, Ag or Li, is required to produce p-type material which is required for an efficient thermoelectric device. Solid solutions and doped compounds have to be annealed in order to produce homogeneous samples – with the same properties throughout. At 800 K, MgSiSnGeBi has been reported to have a figure of merit about 1.4, the highest ever reported for these compounds.
https://en.wikipedia.org/wiki?curid=476993
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The fourth case report was made by Hogewind et al., their patients were 3 affected members of a 2-generation Dutch family (2 brothers and their mother). The three of them suffered from hearing loss ranging from moderate to severe and optic neuropathy but they didn't have any other symptoms, including the ones usually associated with both Wolfram syndrome and Wolfram-like syndrome (such as diabetes mellitus/insipidus or depression), but they did have red-green color deficiency. The elder sibling and the mother were found to have severe hearing loss which heavily diminished their ability at recognizing speech, while the younger brother was relatively okay at doing so. All three individuals were found to have ocular scotoma (also known as blind spot) and neuroretinal rim loss. They were the only affected people with the disorder in their family.
https://en.wikipedia.org/wiki?curid=71946987
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Originally postulated by Maier, Ullman and Vardi, the "Universal Data Model" (UDM) seeks to simplify the query of a complex relational schema by naive users, by creating the illusion that everything is stored in a single giant "universal table". It does this by utilizing inter-table relationships, so that the user does not need to be concerned about what table contains what attribute. C.J. Date, however, pointed out that in circumstances where a table is multiply related to another (as in genealogy databases, where an individual's father and mother are also individuals, or in some business databases where all addresses are stored centrally, and an organization can have different office addresses and shipping addresses), there is insufficient metadata within the database schema to specify unambiguous joins. When UDM has been commercialized, as in SAP BusinessObjects, this limitation is worked around through the creation of "Universes", which are relational views with predefined joins between sets of tables: the "Universe" developer disambiguates ambiguous joins by including the multiply-related table in a view multiple times using different aliases.
https://en.wikipedia.org/wiki?curid=5921339
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In 1953, as a response to growing RAF interest in developing transonic aircraft to serve as a stopgap while the next generation of supersonic fighters were being developed, both Supermarine and Hawker proposed derivatives of their respective Swift and Hunter aircraft. By that time, the shortcomings of the Swift were not yet apparent, which perhaps had allowed Supermarine to gain the RAF's favour for its proposal, designated as the Type 545, over the rival Hawker P.1083. The Type 545 had been drawn up to conform with the requirements given by Specification F.105D. It was to have been capable of attaining Mach 1.3. powered by an Avon engine, promising superior performance to that of the P.1083. The Type 545 bore a resemblance to the Swift, although it was a complete redesign, having an area-ruled fuselage and wing changes. In 1955, work on the project was cancelled, in part due to the considerable difficulties experienced with the Swift.
https://en.wikipedia.org/wiki?curid=690470
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Along with "N. klossii", "N. aristolochioides" is the only species in the genus to employ domed pitchers with translucent patches that allow sunlight to illuminate the interior. When viewed from the front, the peristome and lid appear dark, contrasting heavily against the inner surface of the pitcher, which is brightly lit by light passing through the top of the pitcher dome. It has been suggested that in upper pitchers this adaptation serves to attract flying insects in a similar manner to the North American pitcher plants "Darlingtonia californica", "Sarracenia minor", and "Sarracenia psittacina". A similar trapping mechanism has also been proposed for "N. jacquelineae". This is supported by the fact that most of the prey caught by "N. aristolochioides" consist of small flies, which are attracted to bright light sources. Prey are often disorientated inside the upper pitchers of "N. aristolochioides". Unable to find the exit, they eventually fall into the pitcher fluid and drown. As such, the pitchers have features of lobster-pot traps.
https://en.wikipedia.org/wiki?curid=4831700
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The bracket measures, 5–20 cm in diameter, but in rare cases may be 40 cm wide. The thickness of the bracket varies from 2–12 cm, to 20 cm in exceptional cases. These conks are among the longest persisting fungal fruit bodies, displaying up to eighty annual growth rings. The fungus has small, grayish brown pores whose density is 4–6 per square mm. Its tubes have a length of about 2–7 mm. Each year, the fungus forms a new layer of tubes superimposed on the old layers. Unreleased old spores often find themselves sealed in by later growth that clog the tubes and they appear in cross section as brown spots. The flesh becomes harder with age and dryness, with humidity it softens. The smell of the fruit body has a pronounced mushroom character, the flavor of the meat is bitter. Upon contact with potassium hydroxide, the flesh is dyed black. The spores of the "P. igniarius" form a whitish cast. It is considered to be inedible.
https://en.wikipedia.org/wiki?curid=18518729
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The postcranial skeletal morphology reveals important aspects of "Archaeolemur"’s lifestyle. As the name "monkey lemur" suggests, "Archaeolemur" has often been compared to the Old World monkeys due to convergences in morphological and locomotory features, such as limb proportions. While there are certainly similarities between the two, the convergences are sometimes overstated. A comprehensive analysis of the hands and feet of "Archaeolemur" shows that its limbs are relatively short for its body size, as are the hands and feet. The pollex and hallux are reduced, along with the other digits, and were likely not prehensile; nevertheless, the ability to grasp when climbing was probably retained. "Archaeolemur" has broad apical tufts on the distal phalanges of both the hands and feet, which some have suggested might be related to grooming in the absence of a functioning tooth comb. Unlike the Paleopropithecidae, or "sloth lemurs," who had highly curved proximal phalanges for suspensory behavior, the proximal phalanges of "Archaeolemur" are straighter than those of all extinct Malagasy primates, although still more curved than those of baboons. This morphological data, along with a previous study of the pelvis and scapula, support the conclusion that "Archaeolemur"’s locomotory habits most likely consisted of both terrestrial and arboreal quadrupedalism. It was probably neither cursorial, nor a leaper.
https://en.wikipedia.org/wiki?curid=18986751
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In the United States, the Biomedical Advanced Research and Development Authority (BARDA), a federal agency funding disease-fighting technology, announced investments of nearly billion to support American COVID‑19 vaccine development and manufacture of the most promising candidates. On 16 April, BARDA made a million investment in vaccine developer Moderna and its partner, Johnson & Johnson. BARDA has earmarked an additional billion for development. It will have a role in other programs for development of six to eight vaccine candidates destined for clinical study into 2021 by companies such as Sanofi Pasteur and Regeneron. On 15 May, the government announced funding for a fast-track program called Operation Warp Speed to place multiple vaccine candidates into clinical trials by the fall of 2020 and manufacture 300million doses of a licensed vaccine by January 2021. The project's chief advisor is Moncef Slaoui and its chief operating officer is General Gustave Perna. In June, the Warp Speed team said it would work with seven companies developing vaccine candidates: Moderna, Johnson & Johnson, Merck, Pfizer, the University of Oxford in collaboration with AstraZeneca, and two others, although Pfizer later stated that "all the investment for R&D was made by Pfizer at risk."
https://en.wikipedia.org/wiki?curid=66426813
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Fig. 5 illustrates the operation of a Fourier transform spectrometer, which is essentially a Michelson interferometer with one mirror movable. (A practical Fourier transform spectrometer would substitute corner cube reflectors for the flat mirrors of the conventional Michelson interferometer, but for simplicity, the illustration does not show this.) An interferogram is generated by making measurements of the signal at many discrete positions of the moving mirror. A Fourier transform converts the interferogram into an actual spectrum. Fourier transform spectrometers can offer significant advantages over dispersive (i.e., grating and prism) spectrometers under certain conditions. (1) The Michelson interferometer's detector in effect monitors all wavelengths simultaneously throughout the entire measurement. When using a noisy detector, such as at infrared wavelengths, this offers an increase in signal-to-noise ratio while using only a single detector element; (2) the interferometer does not require a limited aperture as do grating or prism spectrometers, which require the incoming light to pass through a narrow slit in order to achieve high spectral resolution. This is an advantage when the incoming light is not of a single spatial mode. For more information, see Fellgett's advantage.
https://en.wikipedia.org/wiki?curid=582263
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Katz has worked on various aspects of cryptography, computer security, and theoretical computer science. His doctoral thesis was on designing protocols secure against man-in-the-middle attacks, most notably describing an efficient protocol for password-based authenticated key exchange. He has also worked in the areas of secure multi-party computation, public-key encryption, and digital signatures. He has served on the program committees of numerous conferences, including serving as co-program chair for the annual Crypto conference in 2016 and 2017 and co-program chair for the ACM Conference on Computer and Communications Security in 2019-2020. He is also currently an editor of the "Journal of Cryptology," the premier journal of the field.
https://en.wikipedia.org/wiki?curid=40870403
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Many alumni have participated in scientific research. Some have concentrated their studies on the very small universe of atoms and molecules. Nobel laureate Carl D. Anderson (BS 1927, PhD 1930) proved the existence of positrons and muons, Nobel laureate Edwin McMillan (BS 1928, MS 1929) synthesized the first transuranium element, Nobel laureate Leo James Rainwater (BS 1939) investigated the non-spherical shapes of atomic nuclei, and Nobel laureate Douglas D. Osheroff (BS 1967) studied the superfluid nature of helium-3. Donald Knuth (PhD 1963), the "father" of the analysis of algorithms, wrote "The Art of Computer Programming" and created the TeX computer typesetting system, which is commonly used in the scientific community. Bruce Reznick (BS 1973) is a mathematician noted for his contributions to number theory and the combinatorial-algebraic-analytic investigations of polynomials. Narendra Karmarkar (MS 1979) is known for the interior point method, a polynomial algorithm for linear programming known as Karmarkar's algorithm.
https://en.wikipedia.org/wiki?curid=5786
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In March 2011 anonymous bloggers who, by their own admission, stood to gain if ABAT's stock price declined, accused the company of fraudulently misrepresenting its business interests – pointing out discrepancies between Advanced Battery Technologies filings with the Securities and Exchange Commission and China's State Administration of Industry and Commerce, while also questioning the reliability of distributor relationships and related party transactions. Multiple articles followed in financial opinion and analysis sites. While no fraud was ever proved, and a formal rebuttal was issued, the company failed to file its third quarter 2011 financial statements and was subsequently de-listed from trading on the NASDAQ exchange. The events inspired the 2017 finance documentary "The China Hustle".
https://en.wikipedia.org/wiki?curid=32342755
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Though his biographer Des MacHale describes Boole as an "agnostic deist", Boole read a wide variety of Christian theology. Combining his interests in mathematics and theology, he compared the Christian trinity of Father, Son, and Holy Ghost with the three dimensions of space, and was attracted to the Hebrew conception of God as an absolute unity. Boole considered converting to Judaism but in the end was said to have chosen Unitarianism. Boole came to speak against what he saw as "prideful" scepticism, and instead favoured the belief in a "Supreme Intelligent Cause". He also declared "I firmly believe, for the accomplishment of a purpose of the Divine Mind." In addition, he stated that he perceived "teeming evidences of surrounding design" and concluded that "the course of this world is not abandoned to chance and inexorable fate."
https://en.wikipedia.org/wiki?curid=38298
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At a local level, GIS has been frequently used to engage stakeholders in the planning of environmentally "bad" sites. Nuclear power stations, wind farms, landfill sites, and other energy facilities are often subject to NIMBY opposition for aesthetic, health and social reasons. This is despite of their capacity to produce "good" economic factors or employment opportunities. GIS has thus found itself deployed alongside broader cost-benefit analysis (CBA), and multi-criteria decision analysis (MCDA) approaches to socio-political conflict. Environmental Justice (EJ) activists believe these decisions act to further embed racial and class divides. GIS provides an important angle to the EJ movement.
https://en.wikipedia.org/wiki?curid=31783151
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An atmospheric model is a computer program that produces meteorological information for future times at given locations and altitudes. Within any modern model is a set of equations, known as the primitive equations, used to predict the future state of the atmosphere. These equations—along with the ideal gas law—are used to evolve the density, pressure, and potential temperature scalar fields and the air velocity (wind) vector field of the atmosphere through time. Additional transport equations for pollutants and other aerosols are included in some primitive-equation high-resolution models as well. The equations used are nonlinear partial differential equations which are impossible to solve exactly through analytical methods, with the exception of a few idealized cases. Therefore, numerical methods obtain approximate solutions. Different models use different solution methods: some global models and almost all regional models use finite difference methods for all three spatial dimensions, while other global models and a few regional models use spectral methods for the horizontal dimensions and finite-difference methods in the vertical.
https://en.wikipedia.org/wiki?curid=1505381
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At times the High Evolutionary has feigned indifference to the fate of others when his own safety is at stake, only to reveal a considerably more benign agenda later (see the "Annihilation: Conquest" series). More frequently, he has shown a sympathetic and protective concern for the defenseless: on several occasions he has gone to considerable lengths to protect young children, including the critically ill Jessica Drew, Wanda and Pietro Maximoff, and Pietro's daughter Luna. He gave Magda shelter from the elements without hesitation, risked death to fight Galactus over Counter-Earth, and literally begged Ka-Zar not to poison the Earth's biosphere with Isotope E out of compassion for the suffering it would cause. He tried to aid Magneto in reversing the effects of M-Day. He delayed an attack on the Silver Surfer to allow him time to save the life of Suzi Endo, who would briefly become his herald.
https://en.wikipedia.org/wiki?curid=703266
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Co-generation systems can reach 85% efficiency (40–60% electric and the remainder as thermal). Phosphoric-acid fuel cells (PAFC) comprise the largest segment of existing CHP products worldwide and can provide combined efficiencies close to 90%. Molten carbonate (MCFC) and solid-oxide fuel cells (SOFC) are also used for combined heat and power generation and have electrical energy efficiencies around 60%. Disadvantages of co-generation systems include slow ramping up and down rates, high cost and short lifetime. Also their need to have a hot water storage tank to smooth out the thermal heat production was a serious disadvantage in the domestic market place where space in domestic properties is at a great premium.
https://en.wikipedia.org/wiki?curid=11729
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7-24 November 2017. The first of the series of joint Russian-US SIRIUS experiments in which NASA's Human Research Program and IBMP conducted research to identify preventive measures and technologies to protect the health of astronauts during spaceflight, it lasted 17 days. The 6 person crew conducted over 60 experiments, "captured" satellites using a manipulator arm and controlled a rover on the Moon's surface. One experiment consisted of 38-hours of sleep deprivation, during which crew members had to perform a manual VR-simulated docking of the planned Orel spacecraft with a booster rocket in Earth's orbit.
https://en.wikipedia.org/wiki?curid=60312928
1,821,228
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72 East 11th Street was built in 1929 by Holabird & Root, architects of notable Chicago skyscrapers such as the Chicago Board of Trade, the Palmolive Building and the 333 North Michigan Avenue Building. 72 East 11th Street, a six- story, limestone-clad Art Deco building, was originally owned by the Chicago Women's Club and housed the organization's meeting rooms, offices and a theater. Rich in history, it was the site for rallies in support of women's voting rights, efforts on behalf of compulsory education laws and fund raising for scholarships at the School of the Art Institute of Chicago and a women's dormitory at the University of Chicago. Subsequent owners and uses are unknown. Acquired by Columbia in 1980 as the school's Theater Center, it currently houses a renovated 400-seat theater, classrooms, and space for film and photography studios.
https://en.wikipedia.org/wiki?curid=1914203
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Taoism arose as a philosophy and later also developed into a religion based on the texts the "Tao Te Ching" (; "Dào Dé Jīng;" ascribed to Lao Tzu) and the "Zhuangzi" (; partly ascribed to Zhuang Zhou). The character "Dao" literally means 'path' or 'way'. However, in Taoism it refers more often to a meta-physical force that encompasses the entire universe but which cannot be described nor felt. All major Chinese philosophical schools have investigated the correct "Way" to go about a moral life, but in Taoism it takes on the most abstract meanings, leading this school to be named after it. It advocated nonaction ("wu wei"), the strength of softness, spontaneity, and relativism. Although it serves as a rival to Confucianism, a school of active morality, this rivalry is compromised and given perspective by the idiom "practice Confucianism on the outside, Taoism on the inside."
https://en.wikipedia.org/wiki?curid=5822
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FRB 180916, more formally FRB 180916.J0158+65, is a repeating FRB discovered by CHIME, that later studies found to have originated from a medium-sized spiral galaxy (SDSS J015800.28+654253.0) about 500 million light-years away – the closest FRB discovered to date. It is also the first FRB observed to have a regular periodicity. Bursts are clustered into a period of about four days, followed by a dormant period of about 12 days, for a total cycle length of days. Additional followup studies of the repeating FRB by the Swift XRT and UVOT instruments were reported on 4 February 2020; by the Sardinia Radio Telescope (SRT) and Medicina Northern Cross Radio Telescope (MNC), on 17 February 2020; and, by the Galileo telescope in Asiago, also on 17 February 2020. Further observations were made by the Chandra X-ray Observatory on 3 and 18 December 2019, with no significant x-ray emissions detected at the FRB 180916 location, or from the host galaxy SDSS J015800.28+654253.0. On 6 April 2020, followup studies by the Global MASTER-Net were reported on The Astronomer's Telegram. On 25 August 2021, further observations were reported.
https://en.wikipedia.org/wiki?curid=40408388
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The procedure is used as a treatment for carpal tunnel syndrome and according to the American Academy of Orthopaedic Surgeons (AAOS) treatment guidelines, early surgery is an option when there is clinical evidence of median nerve denervation or the patient elects to proceed directly to surgical treatment. Management decisions rely on several factors, including the etiology and chronicity of CTS, symptom severity, and individual patient choices. Nonsurgical treatment measures are appropriate in the initial management of most idiopathic cases of CTS. Splinting and corticosteroid injections may be prescribed, and they have proven benefits. Steroid injections can provide relief if symptoms are of short duration. If no improvement is seen following steroid injection, carpal tunnel release may not be as effective. Surgical treatment is indicated in acute cases of CTS from trauma or infection, in chronic cases with denervation of the abductor pollicis brevis muscle or a pronounced sensory loss, and in cases unresponsive to conservative management.
https://en.wikipedia.org/wiki?curid=38008883
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The earliest practical water-powered machines, the water wheel and watermill, first appeared in the Persian Empire, in what are now Iraq and Iran, by the early 4th century BC. In ancient Greece, the works of Archimedes (287–212 BC) influenced mechanics in the Western tradition. In Roman Egypt, Heron of Alexandria (c. 10–70 AD) created the first steam-powered device (Aeolipile). In China, Zhang Heng (78–139 AD) improved a water clock and invented a seismometer, and Ma Jun (200–265 AD) invented a chariot with differential gears. The medieval Chinese horologist and engineer Su Song (1020–1101 AD) incorporated an escapement mechanism into his astronomical clock tower two centuries before escapement devices were found in medieval European clocks. He also invented the world's first known endless power-transmitting chain drive.
https://en.wikipedia.org/wiki?curid=19528
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There are mainly two types of mathematical models to predict the dynamic stall behaviour: semi-empirical models and computational fluid dynamics method. With regard to the latter method, because of the sophisticated flow field during the process of the dynamic stall, the full Navier-Stokes equations and proper models are adopted, and some promising results have been presented in the literature. However, to utilize this method precisely, proper turbulence models and transition models should be carefully selected. Furthermore, this method is also sometimes too computationally costly for research purposes as well as the pre-design of a helicopter rotor. On the other hand, to date some semi-empirical models have shown their capability of providing adequate precision, which contains sets of linear and nonlinear equations, based on classical unsteady thin-airfoil theory and parameterized by empirical coefficients. Therefore, a large number of experimental results are demanded to correct the empirical coefficients, and it is foreseeable that these models cannot be generally adapted to a wide range of conditions such as different airfoils, Mach numbers, and so on.
https://en.wikipedia.org/wiki?curid=67944776
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In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or MI at one year. This prognostic information was independent of troponin T, ECG and clinical examination. The risk associated with raised H-FABP is dependent upon its concentration. Patients who were TnI negative but H-FABP positive had 17% increased risk of all cause mortality within one year compared to those patients who were TnI positive but H-FABP negative. Currently these TnI positive patients are prioritised for angioplasty, and the TnI negative patients are considered to be of a lower priority, yet the addition of the H-FABP test helps identify patients who are currently slipping through the net and allows physicians to more appropriately manage this hidden high risk group. If both biomarkers were negative, there is 0% mortality at 6 months, in the authors own words this “represents a particularly worthwhile clinical outcome, especially because it was observed in patients admitted into hospital for suspected ACS.” H-FABP indicates risk across the ACS spectrum including UA, NSTEMI or STEMI where low H-FABP concentrations confer low risk whereas high H-FABP concentrations indicate patients who are at a much higher risk of future events.
https://en.wikipedia.org/wiki?curid=26627472
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Irazú is the southernmost of the ten Quaternary volcanoes which form a northwest-trending line through central and northern Costa Rica. Radioactive dating has shown an age of at least 854,000 years with eruption peaks at 570,000 years and the most recent active phase from 136,000 years to present. The most recent activity includes lava flows along with strombolian and phreatomagmatic explosions. Lava types include basalt and andesite erupted during different events suggesting the volcano is fed by two distinct magma chambers. Scientists believed that pulses of magma mixed together in the chamber before climbing upward—a process estimated to take several thousands of years. But Columbia University volcanologists found that the eruption of Costa Rica's Irazu volcano in 1963 was likely triggered by magma that took a nonstop route from the mantle over just a few months. Study authors called it the highway from hell.
https://en.wikipedia.org/wiki?curid=1190369
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Martensite is not shown in the equilibrium phase diagram of the iron-carbon system because it is not an equilibrium phase. Equilibrium phases form by slow cooling rates that allow sufficient time for diffusion, whereas martensite is usually formed by very high cooling rates. Since chemical processes (the attainment of equilibrium) accelerate at higher temperature, martensite is easily destroyed by the application of heat. This process is called tempering. In some alloys, the effect is reduced by adding elements such as tungsten that interfere with cementite nucleation, but more often than not, the nucleation is allowed to proceed to relieve stresses. Since quenching can be difficult to control, many steels are quenched to produce an overabundance of martensite, then tempered to gradually reduce its concentration until the preferred structure for the intended application is achieved. The needle-like microstructure of martensite leads to brittle behavior of the material. Too much martensite leaves steel brittle; too little leaves it soft.
https://en.wikipedia.org/wiki?curid=233266
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The resultant theory was challenged and refined several times in the decades following its original publication in 1971. A significant reappraisal was published in the 1985 essay "Justice as Fairness" and the 2001 book "" in which Rawls further developed his two central principles for his discussion of justice. Together, they dictate that society should be structured so that the greatest possible amount of liberty is given to its members, limited only by the notion that the liberty of any one member shall not infringe upon that of any other member. Secondly, inequalities – either social or economic – are only to be allowed if the worst off will be better off than they might be under an equal distribution. Finally, if there is such a beneficial inequality, this inequality should not make it harder for those without resources to occupy positions of power – for instance, public office.
https://en.wikipedia.org/wiki?curid=243665
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The historical stage of the Empire begun around 1438 when, having settled the disputes with local populations around Cusco, the Incas started the conquest of the coastal valleys from Nasca to Pachacamac and the other regions of Chinchaysuyu. Their strategy involved modifying or constructing a road structure that would ensure the connection of the incorporated territory with Cusco and with other administrative centers, allowing the displacement of troops and officials. The Incas' military advance was based mostly on diplomatic deals before the annexation of the new regions and the consolidation of the dominion, considering war as a last resort. The foundation of cities and administrative centers connected by the road system ensured state control of the new incorporated ethnic groups. Topa Inca Yupanqui succeeded to Pachakutiq, and conquered the Chimu reaching the far north region of Quito around 1463; later he extended the conquests to the jungle region of Charcas and, in the south, to Chile.
https://en.wikipedia.org/wiki?curid=453286
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These and other innovative technologies allow the Renesis to achieve 49% higher output and reduced fuel consumption and emissions. Regarding hydrocarbon (HC) emission characteristics of the RENESIS, the use of the side exhaust port allowed for about 35 – 50% HC reduction compared to the 13B-REW with the peripheral exhaust port. With this reduction, the RENESIS vehicle meets USA LEV-II (LEV). The Renesis won International Engine of the Year and Best New Engine awards 2003 and also holds the "2.5 to 3 liter" (note that the engine is designated as a 1.3–litre by Mazda) size award for 2003 and 2004, where it is considered a 1,3 L engine, but only for the matter of giving awards. This is because a 2-rotor wankel with chambers displaces the same volume in one output shaft rotation as that of a 1,3L four-stroke piston engine. Finally, it was on the Ward's 10 Best Engines list for 2004 and 2005.
https://en.wikipedia.org/wiki?curid=964733
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Up to 10% of the HST's observation time is designated as Director's Discretionary (DD) Time, and is typically awarded to astronomers who wish to study unexpected transient phenomena, such as supernovae. Once Hubble's corrective optics were shown to be performing well, Robert Williams, the then-director of the Space Telescope Science Institute, decided to devote a substantial fraction of his DD time during 1995 to the study of distant galaxies. A special Institute Advisory Committee recommended that the WFPC2 be used to image a "typical" patch of sky at a high galactic latitude, using several optical filters. A working group was set up to develop and implement the project.
https://en.wikipedia.org/wiki?curid=216601
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Whereas ETCS L1 Full Supervision requires supervision to be provided at every signal, ETCS L1 Limited Supervision allows for only a part of the signals to be included, thus allowing to tailor the installation of equipment, only to points of the network where the increase in functionality justifies the cost. Formally, this is possible for all ETCS levels, but it is currently only applied with Level 1. As supervision is not provided at every signal, this implies that cab signalling is not available and the driver must still look out for trackside signals. For this reason, the level of safety is not as high, as not all signals are included and there is still reliance on the driver seeing and respecting the trackside signalling. Studies have shown that "ETCS L1 LS" has the same capacity as plain Level 1 FS for half the cost. Cost advantages come from reduced efforts necessary for calibrating, configuring and designing the track equipment and ETCS telegrams. Another advantage is, that "Limited Supervision" has little requirements for the underlying interlocking, hence it can be applied even on lines with mechanical interlockings as long as LEUs can read respective signal aspects. In contrast Level 2 requires to replace older interlockings with electronic or digital interlockings. That has led to railway operators pushing for the inclusion of "Limited Supervision" into the "ETCS Baseline 3". Although interoperable according to TSI, implementations of "Limited Supervision" are much more diverse than other ETCS modes, e.g. functionality of L1LS in Germany is strongly based on PZB principles of operation and common signal distances.
https://en.wikipedia.org/wiki?curid=2214121
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Although Griffith was well known due to his earlier work on metal fatigue and stress measurement, little work appears to have started as a direct result of his paper. The only obvious effort was a test-bed compressor built by Hayne Constant, Griffith's colleague at the Royal Aircraft Establishment. Other early jet efforts, notably those of Frank Whittle and Hans von Ohain, were based on the more robust and better understood centrifugal compressor which was widely used in superchargers. Griffith had seen Whittle's work in 1929 and dismissed it, noting a mathematical error, and going on to claim that the frontal size of the engine would make it useless on a high-speed aircraft.
https://en.wikipedia.org/wiki?curid=1605425
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The carapace is flattened with smooth side and rear margins, width is up to , and long whip-like antennae grow from the front corners, with the short rostrum extending beyond the large prominent eyes. The animal either filter feeds with long setae borne from the maxilliped palps, or scavenges by chopping up flesh with the second maxilliped and further shredding with the mandibles. The large chelipeds are generally smooth with no teeth or serrations, mainly used for territorial defense among males, who usually have one enlarged. Chelipeds and legs bear randomly located spines which can break off with wear, and these areas are dorsally coloured the same as the carapace, in black, blue, greenish or greyish, the ventral areas lighter. The last pair of legs are setose, reduced in size and carried folded under a large abdominal flap, which also allows the animal to swim backwards. Telson and uropods also setose.
https://en.wikipedia.org/wiki?curid=7825709
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Despite the considerable influence of "Forerunner", naturalists such as Martin Lister (1638–1712) and John Ray (1627–1705) continued to question the organic origin of some fossils. They were particularly concerned about objects such as fossil Ammonites, which Hooke claimed were organic in origin, that did not resemble any known living species. This raised the possibility of extinction, which they found difficult to accept for philosophical and theological reasons. In 1695 Ray wrote to the Welsh naturalist Edward Lluyd complaining of such views: "... there follows such a train of consequences, as seem to shock the Scripture-History of the novity of the World; at least they overthrow the opinion received, & not without good reason, among Divines and Philosophers, that since the first Creation there have been no species of Animals or Vegetables lost, no new ones produced."
https://en.wikipedia.org/wiki?curid=7991116
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