doc_id
int32
18
2.25M
text
stringlengths
245
2.96k
source
stringlengths
38
44
__index_level_0__
int64
18
2.25M
585,510
By January 2015, the SPMAGTF was operating in six countries within CENTCOM. For security concerns and out of deference to foreign partners in the region, it was not given a proper name. The task force flew both kinetic and non-kinetic missions daily in support of Operation Inherent Resolve, the U.S.-led intervention against ISIS. The Marine Corps forces used existing infrastructure to create a partnership capacity site in Iraq designed to increase the capabilities of the Iraqi Security Forces (ISF). In addition, the SPMAGTF took advantage of bilateral training opportunities in theater. The unit participated in Exercise Red Reef with Navy, Marine Corps, and Royal Saudi Navy forces.
https://en.wikipedia.org/wiki?curid=2936492
585,210
1,792,897
The Lawvere programme was to write higher-order logic in terms of category theory. That this can be done cleanly is shown by the book treatment by Joachim Lambek and P. J. Scott. What results is essentially an intuitionistic (i.e. constructive logic) theory, its content being clarified by the existence of a "free topos". That is a set theory, in a broad sense, but also something belonging to the realm of pure syntax. The structure on its sub-object classifier is that of a Heyting algebra. To get a more classical set theory one can look at toposes in which it is moreover a Boolean algebra, or specialising even further, at those with just two truth-values. In that book, the talk is about constructive mathematics; but in fact this can be read as foundational computer science (which is not mentioned). If one wants to discuss set-theoretic operations, such as the formation of the image (range) of a function, a topos is guaranteed to be able to express this, entirely constructively.
https://en.wikipedia.org/wiki?curid=253859
1,791,888
441,386
In 1970, while still a flight director, Lunney was selected as one of the members of a NASA delegation to the Soviet Union, which was to discuss the possibility of cooperation between the two countries in the field of human spaceflight. "For me it was out of the clear blue sky", said Lunney, who was told of the plans while at a conference in early October. "I did not know anything about [the proposed talks] until that time." The trip took place in late October. While in Moscow, Lunney gave a presentation to Soviet engineers on the techniques that NASA used for orbital rendezvous, and on the compromises that would have to be made in order to achieve a rendezvous between American and Soviet spacecraft. The technical agreement that he helped to draft laid the groundwork for the mission which was to become the Apollo–Soyuz Test Project (ASTP). It was intended to be a joint mission, whose highlight was to be a docking between an American Apollo spacecraft and a Soviet Soyuz.
https://en.wikipedia.org/wiki?curid=6393260
441,171
22,002
According to economist Ha-Joon Chang economics should be defined not in terms of its methodology or theoretical approach but in terms of its subject matter. Ha-Joon Chang finds a definition like "the science which studies human behavior as a relationship between ends and scarce means which have alternative uses" very peculiar because all other sciences define themselves in terms of the area of inquiry or object of inquiry rather than the methodology. In the biology department, they don't say that all biology should be studied with DNA analysis. People study living organisms in many different ways, so some people will do DNA analysis, others might do anatomy, and still others might build game theoretic models of animal behavior. But they are all called biology because they all study living organisms. According to Ha Joon Chang, this view that you can and should study the economy in only one way (for example by studying only rational choices), and going even one step further and basically redefining economics as a theory of everything, is very peculiar.
https://en.wikipedia.org/wiki?curid=9223
21,993
2,144,390
The college offers a 5-year-long doctorate program after which scholars graduate with a Ph.D. in Buddhist Studies. Per academic year, the college only accepts 4 new students. This low enrollment number allows for the college to maintain its 20-person capacity in order to provide the most personalized curriculum for students. Each student is expected to craft a study plan to help them master all the necessary skills they will require in order to successfully complete their dissertation. Additionally, besides a supervisor's guidance, due to the small amount of faculty and staff, students may easily obtain thorough feedback and academic advice from professors and specialists besides their own.
https://en.wikipedia.org/wiki?curid=18177297
2,143,159
608,724
Jaeger used her winnings from tennis to create the Silver Lining Foundation in 1990. The foundation's purpose was to provide long term care to children with cancer and children in need. Originally located in Aspen, Colorado, the organization transported groups of young cancer patients to Aspen for a week of support and activities, including horseback riding and whitewater rafting. The foundation also provided money for reunions, family campouts, college scholarships, medical internships, and other programs for children who could not travel. Her foundation is open year round, fundraises for donations to continue providing programs for long term care and a better quality of life to children with cancer and children in need. The first contributor was John McEnroe. Many high-profile celebrities were involved due to respecting Jaeger’s lifetime commitment to helping children with cancer and children in need, including Andre Agassi, Pete Sampras, David Robinson, Cindy Crawford, David Foster and Kevin Costner. In 1996, Jaeger received the Samuel S. Beard Award for Greatest Public Service by an Individual 35 Years or Under, an award given annually by Jefferson Awards.
https://en.wikipedia.org/wiki?curid=862793
608,413
957,898
A final possibility is that dark energy is an illusion caused by some bias in measurements. For example, if we are located in an emptier-than-average region of space, the observed cosmic expansion rate could be mistaken for a variation in time, or acceleration. A different approach uses a cosmological extension of the equivalence principle to show how space might appear to be expanding more rapidly in the voids surrounding our local cluster. While weak, such effects considered cumulatively over billions of years could become significant, creating the illusion of cosmic acceleration, and making it appear as if we live in a Hubble bubble. Yet other possibilities are that the accelerated expansion of the universe is an illusion caused by the relative motion of us to the rest of the universe, or that the supernova sample size used wasn't large enough.
https://en.wikipedia.org/wiki?curid=39136
957,392
1,263,062
Emerging robotic technologies can reduce hazards to workers, but can also introduce new hazards. For example, robotic exoskeletons can be used in construction to reduce load to the spine, improve posture, and reduce fatigue; however, they can also increase chest pressure, limit mobility when moving out of the way of a falling object, and cause balance problems. Unmanned aerial vehicles are being used in the construction industry to do monitoring and inspections of buildings under construction. This reduces the need for humans to be in hazardous locations, but the risk of a UAV collision presents a hazard to workers. For collaborative robots, isolation is not possible. Possible hazard controls include collision avoidance systems, and making the robot less stiff to lessen the impact force.
https://en.wikipedia.org/wiki?curid=56830451
1,262,374
570,672
Continuous monitoring allows examination of how the blood glucose level reacts to insulin, exercise, food, and other factors. The additional data can be useful for setting correct insulin dosing ratios for food intake and correction of hyperglycemia. Monitoring during periods when blood glucose levels are not typically checked (e.g. overnight) can help to identify problems in insulin dosing (such as basal levels for insulin pump users or long-acting insulin levels for patients taking injections). Monitors may also be equipped with alarms to alert patients of hyperglycemia or hypoglycemia so that a patient can take corrective action(s) (after fingerstick testing, if necessary) even in cases where they do not feel symptoms of either condition. While the technology has its limitations, studies have demonstrated that patients with continuous sensors experience a smaller number of hyperglycemic and hypoglycemic events, a reduction in their glycated hemoglobin levels and a decrease in glycemic variability. Compared to intermittent testing, it is likely to help reduce hypertensive complications during pregnancy.
https://en.wikipedia.org/wiki?curid=56557
570,382
1,818,454
Ankyrin-B protein is around 220 kDa, with several isoforms. The "ANK2" gene is approximately 560 kb in size and consists of 53 exons on human chromosome 4; "ANK2" is also transcriptionally regulated via over 30 alternative splicing events with variable expression of isoforms in cardiac muscle. Ankyrin-B is a member of the ankyrin family of proteins, and is a modular protein which is composed of three structural domains: an N-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain and death domain; and a C-terminal regulatory domain which is the least conserved and subject to variation, and determines ankyrin-B activity. The membrane-binding region of ankyrin-B is composed of 24 consecutive ankyrin repeats, and it is the membrane-binding domain of ankyrins that confer functional differences among ankyrin isoforms. Though ubiquitously expressed, ankyrin-B shows high expression levels in cardiac muscle, and is expressed 10-fold lower levels in skeletal muscle, suggesting that ankyrin-B plays a specifically adapted functional role in cardiac muscle.
https://en.wikipedia.org/wiki?curid=18371209
1,817,419
281,330
A dormitory style student community was completed in the summer of 2018. Located at the corner of Slack Street and Grand Avenue, it consists of seven 3- to 5-story concrete framed freshman residence hall buildings with 1,475 beds and an adjacent four-level parking structure. Additional community space for the housing complex and the campus wrap the parking structure on three sides. These spaces include a small café, community room, game room, mail room, welcome center, offices, and maintenance shop. Site improvements include a large open space in the center of the project for activities and group events, volleyball and basketball courts, and outdoor gathering spaces at each building.
https://en.wikipedia.org/wiki?curid=433230
281,177
1,078,112
Influenza viruses, like all viruses in the family Orthomyxoviridae, are enveloped RNA viruses with single stranded genomes. The antigens, matrix protein (M1) and nucleoprotein (NP), are used to determine if an influenza virus is type A, B, C, or D. The M1 protein is required for virus assembly and NP functions in transcription and replication. These viruses also contain proteins on the surface of the cell membrane called glycoproteins. Type A and B have two glycoproteins: hemagglutinin (HA) and neuraminidase (NA). Types C and D have only one glycoprotein: hemagglutinin-esterase fusion (HEF). These glycoproteins allow for attachment and fusion of viral and cellular membranes. Fusion of these membranes allows the viral proteins and genome to be released into the host cell, which then causes the infection. Types C and D are the only influenza viruses to express the enzyme esterase. This enzyme is similar to the enzyme neuraminidase produced by Types A and B in that they both function in destroying the host cell receptors. Glycoproteins may undergo mutations (antigenic drift) or reassortment in which a new HA or NA is produced (antigenic shift). Influenza virus C is only capable of antigenic drift whereas Type A undergoes antigenic shift, as well. When either of these processes occur, the antibodies formed by the immune system no longer protect against these altered glycoproteins. Because of this, viruses continually cause infections.
https://en.wikipedia.org/wiki?curid=3833671
1,077,557
1,933,335
Populations of "T. californicus" along the Pacific coast of North America show a striking pattern of genetic differentiation among populations. Mitochondrial DNA shows particularly large divergences among populations often exceeding twenty percent total sequence divergence. Genetic divergence of a smaller magnitude extends down to a more local scale and this divergence can be stable for longer than two decades for outcrops that are as little as apart, suggesting that dispersal between outcrops must be relatively rare for this copepod. Surprisingly, genetic divergence is much lower among copepod populations from Washington north to Alaska suggesting that copepods may have recolonized these areas since the end of the last ice age. Crosses of copepods from different populations of "T. californicus" have been used to study how reproductive isolation accumulates between diverging population to gain insights into the process of speciation. For crosses between many populations a pattern that has been called hybrid breakdown is observed; this means that first generation hybrids have high survival and reproduction (fitness), while the second generation hybrids have lower and more variable fitness. Deleterious interactions between the mitochondrial genome and nuclear genome may play a large role in the reduction in hybrid fitness observed in many of these crosses.
https://en.wikipedia.org/wiki?curid=41082435
1,932,227
264,675
In a 24 December 2010 "Science" magazine interview entitled "French Nobelist Escapes ‘Intellectual Terror’ to Pursue Radical Ideas in China", he was questioned about his research and plans. In the interview he stated that Jacques Benveniste, whose controversial homeopathic work had been discredited, was "a modern Galileo". When asked if he was not "worried that your colleagues will think you have drifted into pseudo-science", he replied: "No, because it’s not pseudoscience. It’s not quackery. These are real phenomena which deserve further study." He also mentioned that his applications for funding had been turned down and that he was leaving his home country to set up shop in China so he could escape what he called the "intellectual terror" which he claimed had prevented others from publishing their results. He stated that China's Shanghai Jiao Tong University is more "open minded" to his research. There he was chairman of the editorial board of a new journal which published his research.
https://en.wikipedia.org/wiki?curid=837251
264,532
231,901
Many anthropogenic activities like pile driving or even seismic waves can create high-intensity sound waves that cause a certain amount of damage to fish that possess a gas bladder. Physostomes can release air in order to decrease the tension in the gas bladder that may cause internal injuries to other vital organs, while physoclisti can't expel air fast enough, making it more difficult to avoid any major injuries. Some of the commonly seen injuries included ruptured gas bladder and renal Haemorrhage. These mostly affect the overall health of the fish and didn't affect their mortality rate. Investigators used the High-Intensity-Controlled Impedance Fluid Filled (HICI-FT), a stainless-steel wave tube with an electromagnetic shaker. It simulates high-energy sound waves in aquatic far-field, plane-wave acoustic conditions.
https://en.wikipedia.org/wiki?curid=184828
231,782
1,629,826
In 2007 Garet and Jan Hil founded the National Kidney Registry (NKR) after their daughter (age 10) lost her kidney function and needed a transplant. Both parents were incompatible and could not donate to their daughter, who later, after an extensive donor search, received a living donor kidney from her compatible cousin. Mr. Hil was the first non-physician to start/lead a KPD program and the first KPD leader to donate one of his kidneys, starting a chain that facilitated eight transplants. In 2008 the National Kidney Registry completed its first KPD transplants and implemented the next major innovation, the shipment of kidneys on commercial airlines. This breakthrough in logistics further expanded KPD. The first living donor kidney that was shipped on a commercial airline went from New York to Los Angeles and started NKR's second chain which facilitated eight transplants utilizing several bridge donors. Initially NKR provided donors with the option of traveling to the matched recipient's hospital or donating locally and having their kidney shipped. Recipients could also choose if they would accept a shipped kidney or require the donor to travel to their center to donate. Over a two-year period, these preferences shifted until nearly all recipients would accept shipped kidneys with very few donors willing to travel. By 2010 the option to have a donor travel was phased out and all kidneys that needed to be moved between centers were shipped. After several near misses and with the UNOS reporting that 1–2% of deceased donor kidney lost or mis-routed, the NKR developed the first GPS tracking systems for human organs to monitor the location of all NKR kidney shipments. The utilization of GPS tracking devices is now mandatory for all NKR shipped kidneys.
https://en.wikipedia.org/wiki?curid=49687007
1,628,907
1,810,932
Esther Ngumbi grew up in Kwale County, a rural farming community in Kenya. She was introduced to farming at the age of seven, when her parents gave her a strip of land to cultivate cabbages. As a child she became aware of the challenges that farmers faced, including drought and bad soils. The first time she left her village was to attend Kenyatta University, where she earned her Bachelor's and Master's degrees. In 2007 she was awarded an American Association of University Women (AAUW) International Fellowship that allowed her to complete a doctoral degree in entomology at Auburn University. In 2011 she became one of the first people from her community to achieve a doctorate. After earning her PhD she remained at Auburn University as a postdoctoral scholar.
https://en.wikipedia.org/wiki?curid=62643956
1,809,899
462,600
Concurrently, the multisensory neurons of the AES, although also integrally connected to unimodal AES neurons, are not directly connected to the SC. This pattern of division is reflected in other areas of the cortex, resulting in the observation that cortical and tectal multisensory systems are somewhat dissociated. Stein, London, Wilkinson and Price (1996) analysed the perceived luminance of an LED in the context of spatially disparate auditory distracters of various types. A significant finding was that a sound increased the perceived brightness of the light, regardless of their relative spatial locations, provided the light's image was projected onto the fovea. Here, the apparent lack of the spatial rule, further differentiates cortical and tectal multisensory neurons. Little empirical evidence exists to justify this dichotomy. Nevertheless, cortical neurons governing perception, and a separate sub cortical system governing action (orientation behavior) is synonymous with the perception action hypothesis of the visual stream. Further investigation into this field is necessary before any substantial claims can be made.
https://en.wikipedia.org/wiki?curid=1619306
462,371
1,998,677
George Wilson Pierson recruited Whitney to join the Yale University faculty as part of a plan to expand the department's curriculum to include a greater emphasis on Asian history. In 1961, he was named as the A. Whitney Griswold Professor of History, a position he held until his retirement in 1983. Five years after arriving at Yale, Hall published his most famous book, "Government and Local Power in Japan, 500 to 1700," which traced the development of Okayama during that period and, some say, opened up the first thousand years of Japanese history to the English-speaking world. Although scholarly books rarely have a shelf life of more than a generation, some colleagues assert that Hall's book is in a category all its own.
https://en.wikipedia.org/wiki?curid=12891829
1,997,533
1,350,544
The BglBrick assembly standard was proposed by J. Christopher Anderson, John E. Dueber, Mariana Leguia, Gabriel C. Wu, Jonathan C. Goler, Adam P. Arkin, and Jay D. Keasling in September 2009 as a standard very similar in concept to BioBrick, but enabling the generation of fusion proteins without altering the reading frame or introducing stop codons and while creating a relatively neutral amino acid linker scar (GlySer). A BglBrick part is as a DNA sequence flanked by 5′ EcoRI and BglII sites (GAATTCaaaAGATCT) and 3′ BamHI and XhoI sites (GGATCCaaaCTCGAG), and lacking in these same restriction sites internally. The upstream part in the pairwise assembly is purified from an EcoRI/BamHI digest, and the downstream part+vector is purified from an EcoRI/BglII digest. Ligation of these two fragments creates a composite part reforming the original flanking sites required in the part definition and leaving a GGATCT scar sequence at the junction of the parts, a scar that encodes the amino acids glycine and serine when fusing CDS parts together in-frame, convenient due to the GlySer dipeptide being a popular linker of protein domains.
https://en.wikipedia.org/wiki?curid=10837310
1,349,798
2,197,388
William Dod won the competition to best his sister Lottie Dod's result; she won the silver medal in the women's competition. Dod's victory was "pretty clear" by the end of the 80-yard portion of the second round, with him having established a significant lead with only 24 arrows left at 60 yards. The United States' only archer won a bronze medal in this competition, preventing Great Britain from sweeping this event as they did the women's competition and France did the Continental-style event. Henry B. Richardson had the best single-round score of the competition (417 in the second round) but had been well behind the leaders after the first round. Despite starting the second day 50 points behind Reginald Brooks-King, Richardson nearly caught the other man for second place with 3 arrows remaining (down only 1 point, 749 to 748) before Brooks-King pulled away again on the last end, 19–12, for a "close and exciting finish." Ten French archers competed in the York round, though none did better than 16th place.
https://en.wikipedia.org/wiki?curid=4673363
2,196,137
1,275,253
Percussion, or drumming, can produce both short-and long-distance vibrational cues. Direct percussion of the substrate can yield a much stronger signal than an airborne vocalization that couples with the substrate, however, the strength of the percussive cue is related directly to the mass of the animal producing the vibration. Large size is often associated with greater source amplitudes, leading to a greater propagation range. A wide range of vertebrates perform drumming with some part of their body either on the surface or within burrows. Individuals bang heads, rap trunks or tails, stamp or drum with front feet, hind feet or teeth, thump a gular pouch, and basically employ available appendages to create vibrations on the substrates where they live. Insects use percussion by drumming (or scraping) with the head, hind legs, fore legs, mid legs, wings, abdomen, gaster, antennae or maxillary palps.
https://en.wikipedia.org/wiki?curid=28544210
1,274,561
627,697
Wired.com reported on April 13, 2007 that a team from the University of Tehran, competing in a contest sponsored by the American Concrete Institute, demonstrated several blocks of concretes with abnormally high compressive strengths between at 28 days. The blocks appeared to use an aggregate of steel fibres and quartz – a mineral with a compressive strength of 1100 MPa, much higher than typical high-strength aggregates such as granite (). Reactive powder concrete, also known as ultra-high-performance concrete, can be even stronger, with strengths of up to 800 MPa (116,000 PSI). These are made by eliminating large aggregate completely, carefully controlling the size of the fine aggregates to ensure the best possible packing, and incorporating steel fibers (sometimes produced by grinding steel wool) into the matrix. Reactive powder concretes may also make use of silica fume as a fine aggregate. Commercial reactive powder concretes are available in the strength range.
https://en.wikipedia.org/wiki?curid=25234160
627,362
960,158
Aptitude and IQ are different but related concepts relating to human mental ability. Unlike the original idea of IQ, aptitude often refers to one of the many different characteristics which can be independent of each other, such as aptitude for military flight, air traffic control, or computer programming. This approach measures a variety of separate skills, similar to the theory of multiple intelligences and Cattell–Horn–Carroll theory and many other modern theories of intelligence. In general, aptitude tests are more likely to be designed and used for career and employment decisions, and intelligence tests are more likely to be used for educational and research purposes. However, there is a great deal of overlap between them, and they often measure the same kinds of abilities. For example, aptitude tests such as the Armed Services Vocational Aptitude Battery measure enough aptitudes that they could also serve as a measure of general intelligence.
https://en.wikipedia.org/wiki?curid=525009
959,649
35,336
In September 2012, Carnegie Mellon announced the construction of the Sherman and Joyce Bowie Scott Hall on the Pittsburgh campus. The new building is situated between Hamerschlag Hall, Roberts Hall, and Wean Hall and houses the university-wide Wilton E. Scott Institute for Energy Innovation, the Bertucci Nanotechnology Lab, the Engineering Research Accelerator (formerly known as the Institute for Complex Engineered Systems), the Disruptive Health Technologies Institute, and the Department of Biomedical Engineering. Further, in November 2013, Carnegie Mellon announced a $67 million gift from David Tepper, who previously donated $56 million, to develop the Tepper Quadrangle on the north campus. The Tepper Quad includes a new Tepper School of Business facility across Forbes Avenue from a renovated and expanded Heinz College as well as other university-wide buildings and a welcome center which serves as a public gateway to the university.
https://en.wikipedia.org/wiki?curid=48093
35,324
1,300,574
Langmuir circulations (LCs), which are counter-rotating cylindrical roll vortices in the upper ocean, have significant role in vertical mixing. Though they are transient and their strength as well as direction depend on wind and wave properties, they facilitate mixing of nutrients and affect the distribution of marine organisms like plankton in the upper mixed layer of ocean. The wind-generated roll vortices create regions where organisms of different buoyancy, orientation and swimming behavior can aggregate, resulting in patchiness. Indeed, LC can produce significant aggregation of algae during events like red tide. Theoretically, LC size increases with the wind speed unless limited by density discontinuities by pycnocline. But the visibility of surface effects of LC could be limited by the breaking waves during strong winds that disperse the materials present at the surface. So, the surface effects of LC are more likely to be visible during winds stronger than critical wind speed of 3 m/s but not too strong.
https://en.wikipedia.org/wiki?curid=14242868
1,299,860
1,077,872
By 1916 Hamilton had become America's leading authority on lead poisoning. For the next decade she investigated a range of issues for a variety of state and federal health committees. Hamilton focused her explorations on occupational toxic disorders, examining the effects of substances such as aniline dyes, carbon monoxide, mercury, tetraethyl lead, radium, benzene, carbon disulfide and hydrogen sulfide gases. In 1925, at a Public Health Service conference on the use of lead in gasoline, she testified against the use of lead and warned of the danger it posed to people and the environment. Nevertheless, leaded gasoline was allowed. The EPA in 1988 estimated that over the previous 60 years that 68 million children suffered high toxic exposure to lead from leaded fuels.
https://en.wikipedia.org/wiki?curid=1532239
1,077,317
803,097
STS-93 "Columbia" (July 22–27, 1999) was launched at night from the Kennedy Space Center on a five-day mission returning to KSC for the 12th night landing in the Shuttle Program's history. Hawley served as "Columbia"s flight engineer. The primary mission objective was the successful deployment of the Chandra X-ray Observatory, the third of NASA's Great Observatories after Hubble Space Telescope and the Compton Gamma Ray Observatory. Hawley also served as the primary operator of a second telescope carried in the crew module and used for several days to make broadband ultraviolet observations of a variety of Solar System objects. The mission completed 79 orbits in 4 days, 22 hours, and 50 minutes.
https://en.wikipedia.org/wiki?curid=499546
802,668
696,064
Radia Joy Perlman (; born December 18, 1951) is an American computer programmer and network engineer. She is a major figure in assembling the networks and technology to enable what we now know as the internet. She is most famous for her invention of the spanning-tree protocol (STP), which is fundamental to the operation of network bridges, while working for Digital Equipment Corporation, thus earning her nickname "Mother of the Internet". Her innovations have made a huge impact on how networks self-organize and move data. She also made large contributions to many other areas of network design and standardization: for example, enabling today's link-state routing protocols, to be more robust, scalable, and easy to manage.
https://en.wikipedia.org/wiki?curid=4236111
695,700
764,357
Wireless data connections used in mobile computing take three general forms. Cellular data service uses technologies GSM, CDMA or GPRS, 3G networks such as W-CDMA, EDGE or CDMA2000. and more recently 4G and 5G networks. These networks are usually available within range of commercial cell towers. Wi-Fi connections offer higher performance, may be either on a private business network or accessed through public hotspots, and have a typical range of 100 feet indoors and up to 1000 feet outdoors. Satellite Internet access covers areas where cellular and Wi-Fi are not available and may be set up anywhere the user has a line of sight to the satellite's location, which for satellites in geostationary orbit means having an unobstructed view of the southern sky. Some enterprise deployments combine networks from multiple cellular networks or use a mix of cellular, Wi-Fi and satellite. When using a mix of networks, a mobile virtual private network (mobile VPN) not only handles the security concerns, but also performs the multiple network logins automatically and keeps the application connections alive to prevent crashes or data loss during network transitions or coverage loss.
https://en.wikipedia.org/wiki?curid=657187
763,947
1,205,082
Customers that deploy trusted operating systems typically require that the product complete a formal computer security evaluation. The evaluation is stricter for a broader security range, which are the lowest and highest classification levels the system can process. The Trusted Computer System Evaluation Criteria (TCSEC) was the first evaluation criteria developed to assess MLS in computer systems. Under that criteria there was a clear uniform mapping between the security requirements and the breadth of the MLS security range. Historically few implementations have been certified capable of MLS processing with a security range of Unclassified through Top Secret. Among them were Honeywell's SCOMP, USAF SACDIN, NSA's Blacker, and Boeing's MLS LAN, all under TCSEC, 1980s vintage and Intel 80386-based. Currently, MLS products are evaluated under the Common Criteria. In late 2008, the first operating system (more below) was certified to a high evaluated assurance level: Evaluation Assurance Level (EAL) - EAL 6+ / High Robustness, under the auspices of a U.S. government program requiring multilevel security in a high threat environment. While this assurance level has many similarities to that of the old Orange Book A1 (such as formal methods), the functional requirements focus on fundamental isolation and information flow policies rather than higher level policies such as Bell-La Padula. Because the Common Criteria decoupled TCSEC's pairing of assurance (EAL) and functionality (Protection Profile), the clear uniform mapping between security requirements and MLS security range capability documented in CSC-STD-004-85 has largely been lost when the Common Criteria superseded the Rainbow Series.
https://en.wikipedia.org/wiki?curid=1011379
1,204,437
743,410
The physical therapist curriculum consists of foundational sciences (i.e., gross anatomy, cellular histology, embryology, neurology, neuroscience, kinesiology, physiology, exercise physiology, pathology, pharmacology, radiology/imaging, medical screening), behavioral sciences (communication, social and psychologic factors, ethics and values, law, business and management sciences, clinical reasoning and evidence-based practice), and clinical sciences (cardiovascular/pulmonary, endocrine and metabolic, gastrointestinal and genitourinary, integumentary, musculoskeletal, neuromuscular). Coursework also includes material specific to the practice of physical therapy (patient/client management model, prevention, wellness, and health promotion, practice management, management of care delivery, social responsibility, advocacy, and core values). Additionally, students have to engage in full-time clinical practice under the supervision of licensed physical therapists with an expectation of providing safe, competent, and effective physical therapy.
https://en.wikipedia.org/wiki?curid=2110699
743,016
1,105,360
Taking into consideration kinetic theory and assuming that there is the same transition probability in each direction, it is known that formula_19. As formula_15 determines the hopping rate, the previous formula can be rewritten in terms of the mean free path and the mean free time formula_21. Consequently, a relation of formula_15 in terms of the diffusion coefficient is obtainedformula_23.Further considerations can be made in order to study temperature dependence. Therefore, Einstein-Stokes relation is introduced under the consideration of a spherical shapeformula_24, where formula_25 is the material's viscosity.Considering the last two expressions, it is seen that formula_15 formula_27. If formula_28, being formula_29 the melting temperature, the ensemble gains high velocity and makes formula_15 and formula_5 to increase and hence, formula_1 decreases. If formula_33, the ensemble has a low mobility, which makes formula_1 to decrease as well.
https://en.wikipedia.org/wiki?curid=44846612
1,104,797
1,066,312
Saarinen's success didn't go unnoticed as Yamaha contracted him to ride their 250cc and 350cc motorcycles for the 1972 season. The Yamaha factory gave him the second 250cc Yamaha TD-3 (YZ635) after Barry Sheene complained about its performance at the third round in Austria. Saarinen rewarded Yamaha's faith in him by winning the 250cc World Championship in a tight season-long battle with Renzo Pasolini and Rod Gould. He finished second in 350cc World Championship, giving defending champion Giacomo Agostini a strong challenge by winning three races, including a victory at the German Grand Prix held at the daunting Nürburgring race track, where Saarinen defeated Agostini for the first time in a head-to-head race. He also scored a double victory at the Czechoslovakian Grand Prix with victories in both the 250cc and 350cc classes. The threat from Saarinen's performance was so strong that the previously dominant MV Agusta factory was forced to produce a new 350cc motorcycle for Agostini. After the world championship season ended, Saarinen traveled to Great Britain where he won the "Race of the Year" invitational held at Mallory Park.
https://en.wikipedia.org/wiki?curid=2960742
1,065,758
637,802
The American Council of Education recommends an average of 60-80 semester-hours of college credit, in the lower-division baccalaureate/associate degree category, for completion of the entire curriculum including both Nuclear Field "A" School and Naval Nuclear Power School. The variation in total amount depends on the specific pipeline completed — MM, EM, or ET. Further, under the Servicemembers Opportunity Colleges degree program for the Navy (SOCNAV), the residency requirements at these civilian institutions are reduced to only 10-25%, allowing a student to take as little as nine units of coursework (typically three courses) through the degree-granting institution to complete their Associate in Applied Science degree in nuclear engineering technology or as much as 67 units to complete a bachelor's degree in Nuclear Engineering Technology or Nuclear Energy Engineering Technology.
https://en.wikipedia.org/wiki?curid=24008985
637,463
532,361
Unlike any other condition that may present with similar effects, spastic diplegia is entirely congenital in origin—that is, it is almost always acquired shortly before or during a baby's birth process. Things like exposure to toxins, traumatic brain injury, encephalitis, meningitis, drowning, or suffocation do not tend to lead to spastic diplegia in particular or even cerebral palsy generally. Overall, the most common cause of spastic diplegia is Periventricular leukomalacia, more commonly known as neonatal asphyxia or infant hypoxia—a sudden in-womb shortage of oxygen-delivery through the umbilical cord. This sudden lack of oxygen is also almost always combined with premature birth, a phenomenon that, even by itself, would inherently risk the infant developing some type of CP. On the other hand, the presence of certain maternal infections during pregnancy such as congenital rubella syndrome can also lead to spastic diplegia, since such infections can have similar end results to infant hypoxia.
https://en.wikipedia.org/wiki?curid=6115887
532,082
1,390,985
Every manufacturer will use lithium-ion battery cells in pouch format supplied by Saft to build their own battery packs with customised layouts. The batteries will have a maximum energy capacity of 87 kWh and recharge at a rate of up to 700 kW, which will replenish 60% of their capacity in "a few minutes", according to the FIA. On race days, a 45-minute charging interval will occur at a standard rate of approximately 350 kW between hour-long practice, qualifying, and competition rounds, with fast charging limited to three or four minute intervals. According to the invitation to tender bids as the sole supplier of cells, FIA provided total battery weight and volume targets to not exceed and , respectively. Each battery pack is expected to last a single season without degradation in capacity, during which the vehicles are anticipated to race between and experience approximately 200 charging cycles.
https://en.wikipedia.org/wiki?curid=68417962
1,390,214
898,198
The skull of "Psittacosaurus" is highly modified compared to other ornithischian dinosaurs of its time. Extremely tall in height and short in length, the skull has an almost round profile in some species. The portion in front of the orbit (eye socket) is only 40% of total skull length, shorter than any other known ornithischian. The lower jaws of psittacosaurs are characterised by a bulbous vertical ridge down the centre of each tooth. Both upper and lower jaws sport a pronounced beak, formed from the "rostral" and "predentary" bones, respectively. The bony core of the beak may have been sheathed in keratin to provide a sharp cutting surface for cropping plant material. As the generic name suggests, the short skull and beak superficially resemble those of modern parrots. "Psittacosaurus" skulls share several adaptations with more derived ceratopsians, such as the unique rostral bone at the tip of the upper jaw, and the flared jugal (cheek) bones. There is still no sign of the bony neck frill or prominent facial horns which would develop in later ceratopsians. Bony horns protrude from the skull of "P. sibiricus", but these are thought to be an example of convergent evolution.
https://en.wikipedia.org/wiki?curid=2274247
897,724
411,186
Graham wrote that the owner of equity stocks should regard them first and foremost as conferring part ownership of a business. With that perspective in mind, the stock owner should not be too concerned with erratic fluctuations in stock prices, since in the short term the stock market behaves like a voting machine, but in the long term it acts like a weighing machine (i.e. its true value will be reflected in its stock price in the long run). Graham distinguished between the passive and the active investor. The passive investor, often referred to as a defensive investor, invests cautiously, looks for value stocks, and buys for the long term. The active investor, in contrast, is one who has more time, interest, and possibly more specialized knowledge to seek out exceptional buys in the market. Graham recommended that investors spend time and effort to analyze the financial state of companies. When a company is available on the market at a price which is at a discount to its intrinsic value, a "margin of safety" exists, which makes it suitable for investment.
https://en.wikipedia.org/wiki?curid=353206
410,984
2,025,587
Melville was born on 4 April 1944 in Gateshead, Durham, England. He was educated at Clitheroe Royal Grammar School, then an all-boys grammar school in Clitheroe, Lancashire. He studied physics at the University of Sheffield, graduating with a Bachelor of Science (BSc) degree in 1965; he was the first of his family to attend university. Having been awarded a NASA scholarship, he studied for a year at Columbia University in New York City, United States, and graduated with a graduate diploma in space physics. During that year he worked on the Apollo programme of human spaceflight and the preparation of the Apollo 11 moon landing. He then returned to the University of Sheffield to undertake postgraduate research in physics. He completed his Doctor of Philosophy (PhD) degree in 1970.
https://en.wikipedia.org/wiki?curid=50217532
2,024,421
89,065
As shown in the adjacent table, integral proteins are amphipathic transmembrane proteins. Examples of integral proteins include ion channels, proton pumps, and g-protein coupled receptors. Ion channels allow inorganic ions such as sodium, potassium, calcium, or chlorine to diffuse down their electrochemical gradient across the lipid bilayer through hydrophilic pores across the membrane. The electrical behavior of cells (i.e. nerve cells) are controlled by ion channels. Proton pumps are protein pumps that are embedded in the lipid bilayer that allow protons to travel through the membrane by transferring from one amino acid side chain to another. Processes such as electron transport and generating ATP use proton pumps. A G-protein coupled receptor is a single polypeptide chain that crosses the lipid bilayer seven times responding to signal molecules (i.e. hormones and neurotransmitters). G-protein coupled receptors are used in processes such as cell to cell signaling, the regulation of the production of cAMP, and the regulation of ion channels.
https://en.wikipedia.org/wiki?curid=33051527
89,029
521,637
Some of the first dendroolithid eggs—which are attributed to therizinosaurs—were reported from the Bayan Shireh and Nanchao formations on the same year, 1997. These consisted of several egg clutches (a group) with an average composition of 7 or more eggs. In addition, the Bayan Shireh Formation has produced fully grown, specific therizinosaurid taxa, such as "Erlikosaurus" and "Segnosaurus". The egg nests from the Nanchao Formation remained undescribed for several years, only being briefly examined but identified to contain fossilized embryos. However, in 2007 these were described by paleontologist Martin Kundrát and colleagues and tentatively identified as therizinosaurids based on anatomical features such as the tooth-less premaxilla with a downturned edge, dentary with a lateral shelf, teeth with leaf-shaped crowns, humerus with a prominent deltopectoral crest, ilium with an expanded anterior end, and the elongated, sharply-pointed manual unguals. Most eggs have an average size of and given these dimensions, they likely were laid by a medium-sized female. Although several egg clutches were found, one was found containing 7 eggs of which 3 of them were preserving the embryos. In 2019, Hartman and colleagues were the first authors to include these embryos in a phylogenetic analysis and as expected, the embryos were recovered as therizinosaurids.
https://en.wikipedia.org/wiki?curid=3812410
521,365
1,619,953
The second chapter describes the properties of logarithms and give some formulas (in text form) for working with ratios. It ends with a note stating he is delaying publication of his work on constructing logarithms until he sees how his invention is received. Chapter 3 describes the tables and their seven columns, see above. The fourth chapter explains how to use the tables and gives worked examples for sines tangents and secants. He also explains how to get logarithms of numbers directly by using the sine values as the argument and the log-sine values as result and vice versa. He discusses how to deal with different multiples of ten and introduces a notation, similar to modern scientific notation where he appends a number of zeros after the logarithm of a quantity to indicate a need for correction by decades. He give specific logarithm quantities to be added or subtracted in different cases:
https://en.wikipedia.org/wiki?curid=26291704
1,619,038
99,555
Epilepsy monitoring is often considered when patients continue having events despite being on antiseizure medications or if there is concern that the patient's events have an alternate diagnosis, eg: psychogenic non-epileptic seizures, syncope (fainting), sub-cortical movement disorders, migraine variants, stroke etc. In cases of epileptic seizures, continuous EEG monitoring helps to characterize seizures and localize/lateralize the region of brain from which a seizure originates. This can help identify appropriate non-medication treatment options. In clinical use, EEG traces are visually analyzed by neurologists to look at various features. Increasingly, quantitative analysis of EEG is being used in conjunction with visual analysis. Quantitative analysis displays like power spectrum analysis, alpha-delta ratio, amplitude integrated EEG, spike detection can help quickly identify segments of EEG that need close visual analysis or in some cases be used as surrogates for quick identification of seizures in long term recordings.
https://en.wikipedia.org/wiki?curid=21402632
99,512
1,763,616
Reutlingen University (in German "Hochschule Reutlingen"; formerly "FHTW Reutlingen") is a university of applied sciences, involved in education and research. It is located in Reutlingen in the southern German state of Baden-Württemberg. Enrollment stands at about 5,500 students, a quarter of whom are international and exchange students. Reutlingen University has a long tradition as a second home for international students; over a quarter of the students currently registered come from countries outside Germany. The university offers undergraduate and graduate programs in the main fields of International Business, Engineering, Information, Medical and Natural Science and Design. In contrast to common university structures, the orientation of the faculties is less the result of the sciences located there. It rather results from their industry driven specialization. The five schools of Reutlingen University are the School of Applied Chemistry, ESB Business School, the School of Information Technology, the School of Engineering and the School of Texiles & Design. Top Five placements in various rankings and its reputation amongst industry and commerce has made it one of Germany's most prestigious universities of applied sciences.
https://en.wikipedia.org/wiki?curid=545147
1,762,623
546,003
The genus "Lotus" is taxonomically complex. It has at times been divided into subgenera and split into segregate genera, but with no consistent consensus. P.H. Raven in 1971 is said to have been the first to suggest that the "New World" (American) and "Old World" (African and Eurasian) species did not belong in the same genus. A molecular phylogenetic study in 2000 based on nuclear ribosomal ITS sequences confirmed this view. The New World species have been divided between the genera "Hosackia" s.str., "Ottleya", "Acmispon" and "Syrmatium". A 2006 study, primarily concerned with Old World "Lotus" species and hence with limited sampling of the American genera, found that they were all monophyletic. The study also supported the view that "Dorycnium" and "Tetragonolobus" are not distinct from "Lotus" at the generic level. More species were added to the 2006 results in 2008, but did not alter the broad conclusions reached before. Clades were identified within "Lotus" s.str., some of which were significantly different from the sections into which the genus had been divided. However, resolution was incomplete. The results of the analysis were presented in terms of clades and complexes.
https://en.wikipedia.org/wiki?curid=1051693
545,717
347,437
St Andrews is characterised amongst Scottish universities as having a significant number of students who live in university-maintained accommodation. As of 2012, 52% of the student population live in university halls. The halls vary widely in age and character; the oldest, Deans Court dates from the 12th century, and the newest, Whitehorn Hall, built in 2018. They are built in styles from Gothic revival to brutalist. All are now co-educational and non-smoking, and several are catered. The university guarantees every first year student a place of accommodation, and many students return to halls in their second, third and final years at St Andrews. From September 2015 onward, students have had the option of living in alcohol-free flats in David Russell Apartments on the grounds of medical conditions that do not allow drinking or for religious reasons.
https://en.wikipedia.org/wiki?curid=181348
347,256
1,876,880
The journal publishes: review articles reflecting the present state of knowledge in special areas or summarizing limited themes in which discussion has led to clearly defined conclusions; original papers reporting progress and results in all areas of intensive care medicine and its related fields; educational articles giving information on the progress of a topic of particular interest; discussion on technology, methods, new apparatus and modifications of standard techniques; brief reports of uncommon and interesting disorders; correspondence concerning matters of topical interest or relating to published material.
https://en.wikipedia.org/wiki?curid=44533703
1,875,802
876,258
No single test can confirm a diagnosis of JIA: a combination of presenting signs and symptoms, blood tests, and if necessary medical imaging, is used to make the diagnosis. The blood tests may measure levels of inflammatory markers, as well as the presence of specific immune markers which may include anti-nuclear antibody, HLA-B27, rheumatoid factor and anti–citrullinated protein antibody. These serological markers may be negative in children with JIA, and are often present in healthy children; as such they should not be interpreted in isolation but in the context of the clinical presentation. Many children with JIA have normal blood work. X-rays may be required to ensure that the joint pain and swelling is not from a fracture, cancer, infection, or congenital abnormality. In some cases, fluid from the joint can be aspirated and analysed to assist in making a diagnosis. This test can assist by ruling out other causes of arthritis such as infection.
https://en.wikipedia.org/wiki?curid=619071
875,796
1,202,787
Through the use of microsatellite markers, multilocus genotypes identifying a single clonal line of "Symbiodinium" can be resolved from samples of host tissue. It appears that most individual colonies harbor a single multilocus genotype (i.e. clone). Extensive sampling within colonies confirms that many colonies harbor a homogeneous (clonal) "Symbiodinium" population. Additional genotypes do occur in some colonies, yet rarely more than two or three are found. When present in the same colony, multiple clones often exhibit narrow zones of overlap. Colonies adjacent to each other on a reef may harbor identical clones, but across the host population the clone diversity of a particular "Symbiodinium" species is potentially large and comprises recombinant genotypes that are the product of sexual recombination. A clone tends to remain dominant in a colony over many months and years, but may be occasionally displaced or replaced. The few studies examining clone dispersal find that most genotypes have limited geographic distributions, but that dispersal and gene flow is likely influenced by host life history and mode of symbiont acquisition (e. g. horizontal vs. vertical).
https://en.wikipedia.org/wiki?curid=11375187
1,202,144
1,925,767
Commensal bacteria in the GI tract survive despite the abundance of local immune cells. Homeostasis in the intestine requires stimulation of toll-like receptors by commensal microbes. When mice are raised in germ-free conditions, they lack circulating antibodies, and cannot produce mucus, antimicrobial proteins, or mucosal T-cells. Additionally, mice raised in germ-free conditions lack tolerance and often suffer from hypersensitivity reactions. Maturation of the GI tract is mediated by pattern recognition receptors (PRRs), which recognize non-self pathogen associated molecular patterns (PAMPs) including bacterial cell wall components and nucleic acids. These data suggest that commensal microbes aid in intestinal homeostasis and immune system development.
https://en.wikipedia.org/wiki?curid=18291752
1,924,663
364,581
Also in 1846, in Canada, inventor Simeon "Larochelle" Gautron, invented a cannon that was similar to a wooden model of a repeating cannon he constructed in 1836 but for which he had made a number of improvements since then which could be fired 10 or 12 times in a minute when the typical muzzle-loading cannon of the day could be fired at only a fraction of that speed, and an English newspaper reporting on it claimed it could be fired up to 60 times in the same period of time, and clean itself after every shot. It was worked by a crank, could be worked by one man when the typical cannon of the day required twelve or more, was fed by paper cartridges from a revolving cylinder and used separate percussion caps for ignition. Larochelle tried to interest the Canadian military in his invention but was turned down for reasons of complexity and expense which, while it drew some criticism from the French language Canadian press, led to the inventor discontinuing development of it in favour of more profitable activities. A model of Larochelle's cannon is still on display at the Musee National des Beaux-Arts du Quebec.
https://en.wikipedia.org/wiki?curid=19690
364,390
1,476,388
The CX-1 is believed to be made purely for export, as its specifications meet requirements set by the Missile Technology Control Regime (MTCR), which restricts exporting missiles carrying payloads greater than 500 kilograms at ranges exceeding 300 kilometers. Several potential customers have been speculated, including Pakistan since it has been a major recipient of Chinese arms. Other countries include Iran, although they have been attempting to develop domestic missile capabilities to lessen reliance on foreign suppliers, and countries in South America and Africa, but specific countries have not been named and Russia has been an established supplier of similar systems in those areas.
https://en.wikipedia.org/wiki?curid=48806683
1,475,556
907,163
In 1921 Hodgkin's father entered her in the Sir John Leman Grammar School in Beccles, England, where she was one of two girls allowed to study chemistry. Only once, when she was 13, did she make an extended visit to her parents, then living in Khartoum, the capital of Sudan, where her father was Principal of Gordon College. When she was 14, her distant cousin, the chemist Charles Harington (later Sir Charles), recommended D. S. Parsons' "Fundamentals of Biochemistry". Resuming the pre-war pattern, her parents lived and worked abroad for part of the year, returning to England and their children for several months every summer. In 1926, on his retirement from the Sudan Civil Service, her father took the post of Director of the British School of Archaeology in Jerusalem, where he and her mother remained until 1935.
https://en.wikipedia.org/wiki?curid=105825
906,685
1,603,589
This meet had two of the closest finishes. In the women's 100 meters hurdles, the second, third and fourth-place finishers had the same time to the 100th of a second, with winner Kim Turner just one 100th ahead. Stephanie Hightower was the odd person out, not selected to the Olympic team. 28 years later at the 2012 trials, Hightower as President of USATF had to administer over another similar tie in the women's 100 meters between Allyson Felix and Jeneba Tarmoh that could not be separated by photo finish pictures. The other close finish was in the men's 800 meters, where Earl Jones and Johnny Gray both received the same time of 1:43.74 to share the American Record from the same race. And .17 behind them John Marshall and James Robinson also received the same time for the last qualifying place after Robinson kicked past the field and looked to have edged past Marshall, Robinson relaxed at the line while Marshall made one last lean to get the edge and take the final spot on the Olympic team.
https://en.wikipedia.org/wiki?curid=50248366
1,602,688
848,888
Electric cars, as well as plug-in hybrids operating in all-electric mode, emit no harmful tailpipe pollutants from the onboard source of power, such as particulates (soot), volatile organic compounds, hydrocarbons, carbon monoxide, ozone, lead, and various oxides of nitrogen. However, like ICE cars, electric cars emit particulates from brake and tyres. Depending on the source of the electricity used to recharge the batteries, air pollutant emissions are shifted to the location of the generation plants where they can be more easily captured from flue gases. Cities with chronic air pollution problems, such as Los Angeles, México City, Santiago, Chile, São Paulo, Beijing, Bangkok and Kathmandu may also gain local clean air benefits by shifting the harmful emission to electric generation plants located outside the cities.
https://en.wikipedia.org/wiki?curid=23840623
848,438
792,963
In 1936, Joseph Stalin released a requirement for a multipurpose combat aircraft. Codenamed Ivanov, the airplane had to be capable of performing reconnaissance and then attacking the targets it located. P. O. Sukhoi was working in the Tupolev OKB at the time and designed the "Ivanov" aircraft under the tutelage of Andrei Tupolev. The resulting ANT-51 flew on 25 August 1937 with M. M. Gromov at the controls. Powered by a 610 kW (820 hp) Shvetsov M-62 air-cooled radial engine, the ANT-51 reached 403 km/h (220 kn, 250 mph) at 4,700 m (15,420 ft). This was considered insufficient but since the basic design was sound, it was decided to re-test it with a more powerful engine. Equipped with a 746 kW (1,000 hp) Tumansky M-87 engine, the ANT-51 reached 468 km/h (255 kn, 290 mph) at 5,600 m (18,370 ft) and was accepted into production as BB-1 ("Blizhniy Bombardirovschik"; — "short-range bomber"). In 1940, the aircraft was renamed Su-2 and the unreliable M-87 engine was replaced with a Tumansky M-88. This lightened version with an M-88B engine reached 512 km/h (275 kn, 320 mph) in testing.
https://en.wikipedia.org/wiki?curid=392283
792,538
858,401
Pingala (300–200 BCE) was a musical theorist who authored a Sanskrit treatise on prosody. There is evidence that in his work on the enumeration of syllabic combinations, Pingala stumbled upon both the Pascal triangle and Binomial coefficients, although he did not have knowledge of the Binomial theorem itself. A description of binary numbers is also found in the works of Pingala. The Indians also developed the use of the law of signs in multiplication. Negative numbers and the subtrahend had been used in East Asia since the 2nd century BCE, and South Asian mathematicians were aware of negative numbers by the 7th century CE, and their role in mathematical problems of debt was understood. Although the Indians were not the first to use the subtrahend, they were the first to establish the "law of signs" with regards to the multiplication of positive and negative numbers, which did not appear in East Asian texts until 1299. Mostly consistent and correct rules for working with negative numbers were formulated, and the diffusion of these rules led the Arab intermediaries to pass it on to Europe.
https://en.wikipedia.org/wiki?curid=1770300
857,943
675,469
The record of fossil and subfossil sponge spicules is extraordinarily rich and often serves as a basis for far-reaching reconstructions of sponge communities, though spicules are also bearers of significant ecological and environmental information. Specific requirements and preferences of sponges can be used to interpret the environment in which they lived, and reconstruct oscillations in water depths, pH, temperatures, and other parameters, providing snapshots of past climate conditions. In turn, the silicon isotope compositions in spicules (δ30Si) are being increasingly often used to estimate the level of silicic acid in the marine settings throughout the geological history, which enables the reconstruction of past silica cycle and ocean circulation.
https://en.wikipedia.org/wiki?curid=27140295
675,116
239,549
In "Flatland", Abbott describes a society rigidly divided into classes. Social ascent is the main aspiration of its inhabitants, apparently granted to everyone but strictly controlled by the top of the hierarchy. Freedom is despised and the laws are cruel. Innovators are imprisoned or suppressed. Members of lower classes who are intellectually valuable, and potential leaders of riots, are either killed or promoted to the higher classes. Every attempt for change is considered dangerous and harmful. This world is not prepared to receive "revelations from another world". The satirical part is mainly concentrated in the first part of the book, "This World", which describes Flatland. The main points of interest are the Victorian concept of women's roles in the society and in the class-based hierarchy of men. Abbott has been accused of misogyny due to his portrait of women in "Flatland". In his Preface to the Second and Revised Edition, 1884, he answers such critics by emphasizing that the description of women was satirizing the viewpoints held, stating that the Square:
https://en.wikipedia.org/wiki?curid=75214
239,429
789,558
As another indicator, here is the opening paragraph of his 350-page tutorial entitled "Sound" (1867): "In the following pages I have tried to render the science of acoustics interesting to all intelligent persons, including those who do not possess any special scientific culture. The subject is treated experimentally throughout, and I have endeavoured so to place each experiment before the reader that he should realise it as an actual operation." In the preface to the 3rd edition of this book, he reports that earlier editions were translated into Chinese at the expense of the Chinese government and translated into German under the supervision of Hermann von Helmholtz (a big name in the science of acoustics). His first published tutorial, which was about glaciers (1860), similarly states: "The work is written with a desire to interest intelligent persons who may not possess any special scientific culture."
https://en.wikipedia.org/wiki?curid=256310
789,133
41,710
The Renault era started in , with Italian Riccardo Patrese and Belgian Thierry Boutsen at the helm of the two Williams cars. Boutsen replaced Mansell, who had signed on to be Gerhard Berger's teammate at Ferrari. The engine's first Grand Prix in Brazil was one that the team preferred to forget: Boutsen retired with an engine failure and Patrese with an alternator failure after leading, although Patrese did qualify second. The Williams Renault team managed to get back on track with Boutsen coming fourth in the next race at Imola, earning the team three points in their championship campaign. Two races later at the Mexican Grand Prix, the team managed to achieve their first podium with the Renault engine, as Patrese finished second, 15 seconds behind Ayrton Senna. The next race saw Patrese finish second again, having started from 14th on the grid, with Boutsen 6th. At the sixth round in Montreal, Williams not only scored their first win with the Renault engine but also their first one-two: Thierry Boutsen came first followed by Patrese, resulting in 15 points for Williams's championship campaign. Williams came second in the Constructors' Championship, scoring 77 points in total; 64 points behind McLaren. Patrese finished 3rd in the Drivers' Championship with 40 points, 41 points behind the 1989 world champion, Alain Prost. Boutsen finished 5th in the championship with 37 points after also winning in Australia. Boutsen's win in Australia gave Williams the distinction of having won the first and last Grands Prix of the 1980s.
https://en.wikipedia.org/wiki?curid=34104
41,695
1,604,082
According to the school's official website in June 2016, in recent years, the school has obtained 1,452 scientific research projects of various levels and received 470 million yuan in funding. Among them, there are 289 projects including the National Science and Technology Support Plan, the National Basic Research and Development Plan (973), the National High-Tech Research and Development Plan (863), the National Natural Science Foundation of China, and the National Philosophy and Social Science Foundation. Completed 790 various scientific research projects and obtained 488 achievements, including 10 internationally advanced, 32 internationally advanced, and 35 new varieties cultivated. Won 1 National Science and Technology Progress Award, 1 Second Prize, 2 National Teaching Achievement Awards, 2 First Prizes for Science and Technology Progress of the Ministry of Education, 2 Major Contribution Awards for Science and Technology in Qinghai Province, and Science and Technology Progress Award of Qinghai There are 35 awards and 13 awards for philosophy and social sciences of Qinghai Province. Published more than 7,900 academic papers in various domestic and foreign journals, and published 3 academic papers in top international academic journals "Science" and "Nature".
https://en.wikipedia.org/wiki?curid=1750049
1,603,181
1,737,774
In summer 2001, Ruggeri sought to improve the team's performances by selling youth players to economically stronger teams (Pelizzoli to reigning champion Roma, Cristian Zenoni and Massimo Donati to Milan) and using that money to bring more famous players to the club. Among them was forward Gianni Comandini, whose 30-billion lire purchase was Atalanta's most expensive at the time. However, the new arrivals did not mix well with the squad or lead to improved results. Atalanta eventually would finish in ninth place that season, though with one more point than the previous season. The 2001–02 season also saw good performances of attacking midfielder Cristiano Doni, who was already part of the first team under Mutti in 1998; he scored 16 goals for Atalanta in 30 appearances, earning a call-up to the Italian national team for the 2002 FIFA World Cup.
https://en.wikipedia.org/wiki?curid=66131596
1,736,797
1,134,758
The Earth Observing System (EOS) is a program of NASA comprising a series of artificial satellite missions and scientific instruments in Earth orbit designed for long-term global observations of the land surface, biosphere, atmosphere, and oceans. Since the early 1970s, NASA has been developing its Earth Observing System, launching a series of LANDSAT satellites in the decade. Some of the first included Passive-Microwave imaging in 1972 through the Nimbus 5 Satellite. Following the launch of various satellite missions, the conception of the program began in the late 80s and expanded rapidly through the 90s. Since the inception of the program, it has continued to develop to what we can collect in data today, including; land, sea, radiation and atmosphere. Collected in a system known as EOSDIS, NASA uses this data in order to study the progression and changes in the biosphere of Earth. The main focus of this data collection surrounds climatic science. The program is the centrepiece of NASA's Earth Science Enterprise (ESE).
https://en.wikipedia.org/wiki?curid=471278
1,134,165
441,623
Each Campus has modern facilities on commercial sized farms and offers Year 10, 11 and 12 programs for male and female students. The students study a range of School Curriculum and Standards Authority subjects leading to Secondary Graduation and the Western Australian Certificate of Education and also complete vocational qualifications from Industry Training Packages. The major focus is on the study of agriculture but the program may also include horticulture, viticulture, equine, aquaculture, forestry, building construction, metals and engineering and automotive. Each Campus offers some specialist programs that can lead to tertiary study and apprenticeships and careers in a range of agriculture related vocations.
https://en.wikipedia.org/wiki?curid=2604065
441,408
2,039,342
In 1990, Ross Kamakahi Jr., president of the Associated Students of Leeward Community College, and Keith Kamisugi, president of ASUH-Manoa, worked with a team of students from each campus of the system to create a coalition of student governments. Through several organizing meetings, most taking place in conjunction with the rotating meetings of the UH Board of Regents, the students agreed upon an affiliation that exists today as the University of Hawai'i Student Caucus (UHSC). Although the UHSC now functions as an entity recognized and supported by the university administration, it initially was meant to function as an unincorporated association outside of the administration in order to provide the highest degree of independence. Kamakahi and Kamisugi were elected the initial co-chairs of the UHSC. Although each campus had different levels of enrollment, the UHSC founders decided to set two delegates per campus in effort to recognize the importance of each campus, regardless of size.
https://en.wikipedia.org/wiki?curid=31189887
2,038,163
1,380,451
Hutchinson was born in 1903 to Arthur and Evaline D. Hutchinson. He grew up in Cambridge, England. His father was a mineralogist at the University of Cambridge. Hutchinson grew up surrounded by intellectuals, including two of Darwin's sons. By the age of five, Hutchinson was already collecting aquatic creatures and studying their preferred living environment in aquariums that he manufactured himself. He had a younger brother and a younger sister. He had his early education at Saint Faith's. He went on in 1917 to study at Gresham's School in Norfolk. Gresham's was unique in not focusing on the classics, but including more intensive studies of mathematics and science, along with modern languages and history. It was here that he began to notice that organisms had different chemical environments. Hutchinson was admitted to read zoology at Emmanuel College, Cambridge, graduating in 1925.
https://en.wikipedia.org/wiki?curid=2321755
1,379,688
1,771,868
Major city-states and sacred places of pilgrimage in the Hellenic World were Argos, Athens, Eleusis, Corinth, Delphi, Ithaca, Olympia, Sparta, Thebes, Thrace and Mount Olympus, the home of the gods. The gods played an important part in the lives of the people; so much so that one could face execution for questioning - or even allegedly questioning - their existence, as in the case of Protagoras, Socrates and Alcibiades (the Athenian statesman Critias, sometimes referred to as `the first atheist', only escaped condemnation because he was so powerful). Great works of art and beautiful temples were created for the worship and praise of the various gods and goddesses of the Greeks such as the Parthenon of Athens, dedicated to the goddess Athena Parthenos (Athena the Virgin) and the Temple of Zeus (listed as an Ancient Wonder) at Olympia (both works to which Phidias contributed). The temple of Demeter at Eleusis was the site of the famous Eleusinian Mysteries and is considered the most important rite in ancient Greece. In his works, "The Iliad" and "The Odyssey", immensely popular and influential in the Hellenic World, Homer depicted the gods and goddesses as intimately involved in the lives of the people. The deities were regularly consulted in domestic matters as well as affairs of state. The Oracle at Delphi was considered so important at the time that people from all over the known world came to Greece to ask advice or favors from the god. It was considered vital to consult with the supernatural forces before embarking on any military campaign.
https://en.wikipedia.org/wiki?curid=21792815
1,770,871
1,185,627
Each chapter is named by a possible, or improbable, technology of the future. After a look at the development of today's technology, there is discussion as to how this advanced technology might become a reality. Chapters become somewhat more general towards the end of the book. Some of our present day technologies are explained, and then extrapolated into futuristic applications. In the future, current technologies are still recognizable, but in a slightly altered form. For example, when discussing force fields of the future, Dr. Kaku writes about cutting edge laser technology, and newly developed plasma windows. These are two of several technologies, which he sees as required for creating a force field. To create a force field these would be combined in a slightly altered form, such as more precise or more powerful. Furthermore, this discussion on force fields, as well as on the pantheon of highly advanced technologies, remains as true to the original concepts (as in how the public generally imagines advanced technologies) as possible, while remaining practical. Kaku concludes his book with a short epilogue detailing the newest frontiers in physics and how there is still much more to be learned about physics and our universe.
https://en.wikipedia.org/wiki?curid=18493302
1,184,998
211,885
The cornerstone of treatment is administration of free water to correct the relative water deficit. Water can be replaced orally or intravenously. Water alone cannot be administered intravenously (because of osmolarity issues leading to rupturing of red blood cells in the bloodstream), but rather can be given intravenously in solution with dextrose (sugar) or saline (salt). However, overly rapid correction of hypernatremia is potentially very dangerous. The body (in particular the brain) adapts to the higher sodium concentration. Rapidly lowering the sodium concentration with free water, once this adaptation has occurred, causes water to flow into brain cells and causes them to swell. This can lead to cerebral edema, potentially resulting in seizures, permanent brain damage, or death. Therefore, significant hypernatremia should be treated carefully by a physician or other medical professional with experience in treatment of electrolyte imbalance. Specific treatments such as thiazide diuretics (e.g., chlorthalidone) in congestive heart failure or corticosteroids in nephropathy also can be used.
https://en.wikipedia.org/wiki?curid=996303
211,777
356,835
Mast cells serve an important immunological role by defending the body from antigens and maintaining homeostasis in the gut microbiome. They act as an alarm to trigger inflammatory responses by the immune system. Their presence in the digestive system enables them to serve as an early barrier to pathogens entering the body. People who suffer from widespread sensitivities and allergic reactions may have mast cell activation syndrome (MCAS), in which excessive amounts of histamine are released from mast cells, and cannot be properly degraded. The abnormal release of histamine can be caused by either dysfunctional internal signals from defective mast cells or by the development of clonal mast cell populations through mutations occurring in the tyrosine kinase Kit. In such cases, the body may not be able to produce sufficient degradative enzymes to properly eliminate the excess histamine. Since MCAS is symptomatically characterized as such a broad disorder, it is difficult to diagnose and can be mislabeled as a variety of diseases, including irritable bowel syndrome and fibromyalgia.
https://en.wikipedia.org/wiki?curid=395877
356,649
1,592,755
Professor Paul Korner , a cardiac physiologist noted for his contributions to the understanding of hypertension, took on the role of director in 1975 and by this time, the sole focus of the institute was cardiovascular disease research. Significant advancements during this time included new strategies for hypertension; greater understanding of the role of the autonomic nervous system; insight into the role of cholesterol in atherogenesis and triglycerides as an independent risk factor for coronary atherosclerosis. Notable investigators included Paul Nestel (nutrition, CVD, atherosclerosis and lipid metabolism), Murray Esler (causes and treatment of high blood pressure and heart failure, and effects of stress on the cardiovascular system) and Garry Jennings (causes, prevention and treatment of CVD, and relationship between exercise, blood pressure, sympathetic nervous system activity and glucose metabolism).
https://en.wikipedia.org/wiki?curid=20421434
1,591,858
123,208
The respiratory system may compensate for dropping oxygen levels through hyperventilation, though a sudden ischemic episode may also proceed faster than the respiratory system can respond. These processes cause the typical symptoms of fainting: pale skin, rapid breathing, nausea, and weakness of the limbs, particularly of the legs. If the ischemia is intense or prolonged, limb weakness progresses to collapse. The weakness of the legs causes most people to sit or lie down if there is time to do so. This may avert a complete collapse, but whether the patient sits down or falls down, the result of an ischaemic episode is a posture in which less blood pressure is required to achieve adequate blood flow. An individual with very little skin pigmentation may appear to have all color drained from his or her face at the onset of an episode. This effect combined with the following collapse can make a strong and dramatic impression on bystanders.
https://en.wikipedia.org/wiki?curid=20254750
123,159
1,177,501
The SUNY Canton ice hockey program began in the mid-1960s and has won 15 NJCAA National Championships in: 1973, 1974, 1975, 1976, 1978, 1979, 1981, 1982, 1983, 1987, 1989, 1992, 1996, 1997, and 2000. The team currently competes in the Division III (NCAA) level as it was awarded independent status with eventual admittance into the SUNY conference. In its second season as a member of the ACHA, the Roos reached the 2010 ACHA Division I National Tournament before falling to Penn State 3–7 in the first round. The Roos won their second straight ECHL regular season championship and first ever conference playoff championship in 2011. The team also made a second straight appearance in the ACHA DI Championship.
https://en.wikipedia.org/wiki?curid=561610
1,176,878
1,466,221
Leiserson's dissertation, "Area-Efficient VLSI Computation", won the first ACM Doctoral Dissertation Award. In 1985, the National Science Foundation awarded him a Presidential Young Investigator Award. He is a Fellow of the Association for Computing Machinery (ACM), the American Association for the Advancement of Science (AAAS), the Institute of Electrical and Electronics Engineers (IEEE), and the Society for Industrial and Applied Mathematics (SIAM). He received the 2014 Taylor L. Booth Education Award from the IEEE Computer Society "for worldwide computer science education impact through writing a best-selling algorithms textbook, and developing courses on algorithms and parallel programming." He received the 2014 ACM-IEEE Computer Society Ken Kennedy Award for his "enduring influence on parallel computing systems and their adoption into mainstream use through scholarly research and development." He was also cited for "distinguished mentoring of computer science leaders and students." He received the 2013 ACM Paris Kanellakis Theory and Practice Award for "contributions to robust parallel and distributed computing."
https://en.wikipedia.org/wiki?curid=1400884
1,465,398
468,104
Cheminformatics has been an active field in various guises since the 1970s and earlier, with activity in academic departments and commercial pharmaceutical research and development departments. The term chemoinformatics was defined in its application to drug discovery by F.K. Brown in 1998:Chemoinformatics is the mixing of those information resources to transform data into information and information into knowledge for the intended purpose of making better decisions faster in the area of drug lead identification and optimization. Since then, both terms, cheminformatics and chemoinformatics, have been used, although, lexicographically, cheminformatics appears to be more frequently used, despite academics in Europe declaring for the variant chemoinformatics in 2006. In 2009, a prominent Springer journal in the field was founded by transatlantic executive editors named the Journal of Cheminformatics.
https://en.wikipedia.org/wiki?curid=575697
467,869
1,227,728
In particular, dependency links in a decision model represent cause-and-effect (as in a causal loop diagram), data flow (as in a data flow diagram), or other relationships. As an example, one link might represent the connection between "mean time to repair a problem with telephone service" and "customer satisfaction", where a short repair time would presumably raise customer satisfaction. The functional form of these dependencies can be determined by a number of approaches. Numerical approaches, which analyze data to determine these functions, include machine learning and analytics algorithms (including artificial neural networks), as well as more traditional regression analysis. Results from operations research and many other quantitative approaches have a similar role to play.
https://en.wikipedia.org/wiki?curid=20269843
1,227,066
498,778
The inbreeding coefficient (f) was introduced in the early section on Self Fertilization. Here, a formal definition of it is considered: f is the probability that two "same" alleles (that is A and A, or a and a), which fertilize together are of common ancestral origin—or (more formally) f is the probability that two homologous alleles are autozygous. Consider any random gamete in the "potential" gamodeme that has its syngamy partner restricted by binomial sampling. The probability that that second gamete is homologous autozygous to the first is 1/(2N), the reciprocal of the gamodeme size. For the five example progenies, these quantities are 0.1, 0.0833, 0.1, 0.0833 and 0.125 respectively, and their weighted average is 0.0961. This is the "inbreeding coefficient" of the example progenies bulk, provided it is "unbiased" with respect to the full binomial distribution. An example based upon "s = 5" is likely to be biased, however, when compared to an appropriate entire binomial distribution based upon the sample number ("s") approaching infinity ("s → ∞"). Another derived definition of f for the full Distribution is that f also equals the rise in homozygosity, which equals the fall in heterozygosity. For the example, these frequency changes are "0.1069" and "0.1070", respectively. This result is different to the above, indicating that bias with respect to the full underlying distribution is present in the example. For the example "itself", these latter values are the better ones to use, namely f = 0.10695.
https://en.wikipedia.org/wiki?curid=297382
498,521
1,249,441
In December 2014, Audi DTM Project Leader Andreas Roos and his fellow engineers at Audi Sport take the first step towards the new Audi RS 5 DTM, which marks Audi's biggest and most important touring car project in recent history. Shortly before the project's launch, the course has been set in terms of crucial elements of a joint future of the DTM and the Japanese Super GT racing series according to the Class 1 regulations. The first preparation of Audi RC8 2.0 TFSI inline-4 turbo engine was commenced in January 2015. The initial and key element of the mission: a new two-litre four-cylinder internal combustion engine with an exhaust gas turbocharger for racing, starting in the 2017 DTM season that was envisaged at that time.
https://en.wikipedia.org/wiki?curid=61615343
1,248,765
1,934,838
One of the problems that restricted the astronomical work of the Observatory during this period was that Balgay Park was enclosed, and the gates were locked at dusk. Special arrangements had to be made with the Parks Department to have a gatekeeper on duty during the nights when the telescope was in use, and for him to supervise entry and exit of public and cars, and ensure no-one was left in the park after the observatory was locked up. This meant that all children had to be accompanied by an adult. For this reason the Council placed the Observatory under the administrative control of the Parks Superintendent, under whom it remained until reorganisation brought a transfer to the Museums Department. The railings were removed during the War, since when the park has had "open access." During the years 1935 to 1939 there was one staff change - Mr. Dorward retired and was succeeded by Mr. McDonald. Shortly after the outbreak of the Second World War the Observatory was closed for the duration and the staff re-deployed to work of more immediate national importance. After the war, when the Observatory re-opened, the telescope underwent a radical transformation.
https://en.wikipedia.org/wiki?curid=9898493
1,933,730
383,818
The first fire arrows were arrows strapped with gunpowder incendiaries but they eventually became gunpowder propelled projectiles (rockets). It's not certain when this happened. According to the "History of Song", in 969 two Song generals, Yue Yifang and Feng Jisheng (馮繼升), invented a variant fire arrow which used gunpowder tubes as propellants. These fire arrows were shown to the emperor in 970 when the head of a weapons manufacturing bureau sent Feng Jisheng to demonstrate the gunpowder arrow design, for which he was heavily rewarded. However Joseph Needham argues that rockets could not have existed before the 12th century, since the gunpowder formulas listed in the "Wujing Zongyao" are not suitable as rocket propellant. According to Stephen G. Haw, there is only slight evidence that rockets existed prior to 1200 and it is more likely they were not produced or used for warfare until the latter half of the 13th century. Rockets are recorded to have been used by the Song navy in a military exercise dated to 1245. Internal-combustion rocket propulsion is mentioned in a reference to 1264, recording that the 'ground-rat,' a type of firework, had frightened the Empress-Mother Gongsheng at a feast held in her honor by her son the Emperor Lizong.
https://en.wikipedia.org/wiki?curid=12063194
383,623
331,096
The first of two Laboratory Cabin Modules (LCM), "Wentian", provides additional avionics, propulsion, and life support systems as backup functions for the CCM. The "Wentian" is also fitted with an independent airlock cabin to serve as the main entry-exit point for extravehicular activities (EVA), replacing the "Tianhe" docking hub. For the scientific payload, the LCM is equipped with multiple internal science racks and 22 payload adapters on the exterior for various types of experiments. Aside from scientific equipment, the module features three additional living quarters designed for short-term stay, which will be used during crew rotation. "Wentian" was launched and docked with the "Tianhe" on 24 July 2022.
https://en.wikipedia.org/wiki?curid=2481401
330,919
849,621
The endosymbionts of "R. pachyptila" are not passed to the fertilized eggs during spawning, but are acquired later during the larval stage of the vestimentiferan worm. "R. pachyptila" planktonic larvae that are transported through sea-bottom currents until they reach active hydrothermal vents sites, are referred to as trophocores. The trophocore stage lacks endosymbionts, which are acquired once larvae settle in a suitable environment and substrate. Free-living bacteria found in the water column are ingested randomly and enter the worm through a ciliated opening of the branchial plume. This opening is connected to the trophosome through a duct that passes through the brain. Once the bacteria are in the gut, the ones that are beneficial to the individual, namely sulfide- oxidizing strains are paghocytized by epithelial cells found in the midgut are then retained. Bacteria that do not represent possible endosymbionts are digested. This raises questions as to how "R. pachyptila" manages to discern between essential and nonessential bacterial strains. The worm's ability to recognise a beneficial strain, as well as preferential host-specific infection by bacteria have been both suggested as being the drivers of this phenomenon.
https://en.wikipedia.org/wiki?curid=550334
849,169
1,422,862
During World War II, the entire Class of 1944 was drafted and only 2 graduated. By 1943 so many cadets had left school to join the military that enrollment had dropped to less than 500 but was soon bolstered with the addition of active duty service members attending as part of the Army Specialized Training Program. Of the 2,976 living alumni in 1946 all but 49 served their country. Citadel alumni were members of some of the most famous units of the war to include the Flying Tigers, the Doolittle Raiders and the RAF Eagle Squadrons; 280 alumni were Killed in Action, 67 were declared Missing and 65 became Prisoners of War. In the immediate postwar period veteran students utilizing the GI Bill swelled the size of the school to record levels and at one time outnumbered cadets more than 2 to 1.
https://en.wikipedia.org/wiki?curid=48639384
1,422,061
648,547
In its original form, twistor theory encodes physical fields on Minkowski space into complex analytic objects on twistor space via the Penrose transform. This is especially natural for massless fields of arbitrary spin. In the first instance these are obtained via contour integral formulae in terms of free holomorphic functions on regions in twistor space. The holomorphic twistor functions that give rise to solutions to the massless field equations can be more deeply understood as Čech representatives of analytic cohomology classes on regions in formula_1. These correspondences have been extended to certain nonlinear fields, including self-dual gravity in Penrose's nonlinear graviton construction and self-dual Yang–Mills fields in the so-called Ward construction; the former gives rise to deformations of the underlying complex structure of regions in formula_1, and the latter to certain holomorphic vector bundles over regions in formula_1. These constructions have had wide applications, including inter alia the theory of integrable systems.
https://en.wikipedia.org/wiki?curid=260836
648,206
1,896,534
PCFT is located on chromosome 17q11.2 and consists of five exons encoding a protein with 459 amino acids and a MW of ~50kDa. PCFT is highly conserved, sharing 87% identity to the mouse and rat PCFT and retaining more than 50% amino acid identity to the frog (XP415815) and zebrafish (AAH77859) proteins. Structurally, there are twelve transmembrane helices with the N- and C- termini directed to the cytoplasm and a large internal loop that divides the molecule in half. There are two glycosylation sites (N58, N68) and a disulfide bond connecting residues C66, in the 1st and C298 in the 4th, external loop. Neither glycosylation nor the disulfide bond are essential for function. Residues have been identified that play a role in proton-coupling, proton binding, folate binding and oscillation of the carrier between its conformational states. PCFT forms oligomers and some of the linking residues have been identified.
https://en.wikipedia.org/wiki?curid=48538082
1,895,450
1,062,071
Diagnostics involves the detection of antigens and antibodies in blood samples; the profiling of sera to discover new disease biomarkers; the monitoring of disease states and responses to therapy in personalized medicine; the monitoring of environment and food. Digital bioassay is an example of using protein microarray for diagnostic purposes. In this technology, an array of microwells on a glass/polymer chip are seeded with magnetic beads (coated with fluorescent tagged antibodies), subjected to targeted antigens and then characterised by a microscope through counting fluorescing wells. A cost-effective fabrication platform (using OSTE polymers) for such microwell arrays has been recently demonstrated and the bio-assay model system has been successfully characterised.
https://en.wikipedia.org/wiki?curid=1659679
1,061,517
1,747,896
After passing the Bonin Islands the South Seas squadron stopped at the Marianas but finding no sign of enemy ships pushed on rapidly as possible towards the Marshalls arriving at Eniwetok Atoll on September 29. The squadron's ultimate objective, however, was Jaluit Atoll which was the German commercial headquarters in the central Pacific. Anchoring off Jaluit on September 30, the Japanese found the vast lagoon empty and put a landing party ashore. The handful of German authorities on the island made no attempt to resist or to stir up the native population. After gaining control of the atoll, Vice-Amiral Yamaya radioed his report to naval headquarters in Tokyo. Instructions came back almost immediately, Yamaya was ordered to withdraw the landing party and that the South Seas squadron was to retire to Eniwetok. Yamaya complied and left westward only to receive further orders a few days later, stating that he was to return and land a permanent occupying force on Jaluit. On October 3, a permanent landing party of three officers and one hundred enlisted men was put ashore.
https://en.wikipedia.org/wiki?curid=56104666
1,746,910
776,730
Using negatively marked clones is sometimes inconvenient, especially when generating very small patches of cells, where seeing a dark spot on a bright background is more difficult than a bright spot on a dark background. Creating positively marked clones is possible using the so-called MARCM ("mosaic analysis with a repressible cell marker" system, developed by Liqun Luo, a professor at Stanford University, and his postdoctoral student Tzumin Lee, who now leads a group at Janelia Farm Research Campus. This system builds on the GAL4/UAS system, which is used to express GFP in specific cells. However, a globally expressed "GAL80" gene is used to repress the action of GAL4, preventing the expression of GFP. Instead of using GFP to mark the wild-type chromosome as above, GAL80 serves this purpose, so that when it is removed by mitotic recombination, GAL4 is allowed to function, and GFP turns on. This results in the cells of interest being marked brightly in a dark background.
https://en.wikipedia.org/wiki?curid=604020
776,314
1,121,037
Networks can consist of anything from families, project teams, classrooms, sports teams, legislatures, nation-states, disease vectors, membership on networking websites like Twitter or Facebook, or even the Internet. Networks can consist of direct linkages between nodes or indirect linkages based upon shared attributes, shared attendance at events, or common affiliations. Network features can be at the level of individual nodes, dyads, triads, ties and/or edges, or the entire network. For example, node-level features can include network phenomena such as betweenness and centrality, or individual attributes such as age, sex, or income. SNA software generates these features from raw network data formatted in an edgelist, adjacency list, or adjacency matrix (also called sociomatrix), often combined with (individual/node-level) attribute data. Though the majority of network analysis software uses a plain text ASCII data format, some software packages contain the capability to utilize relational databases to import and/or store network features.
https://en.wikipedia.org/wiki?curid=15919460
1,120,463
2,090,359
He left the Institute of Pathological Anatomy of Berlin, taking advantage of the outbreak of the Franco-Prussian War, in which he participated as head of the German Red Cross. On that occasion a Prussian frontline soldier had an impressive haemorrhage from the rupture of the subclavian vein. Taking the patient to the rear would have been too risky and valuable time would have been wasted. Durante decides to run to the front in no man's land with the risk of being hit by the opposing fire, he manages to block the bleeding and attach the stumps of the interrupted vase. For this gesture, when the Prussian ambassador reaches Paris, he seeks Durante, to award him an honour on behalf of the King of Prussia, but does not find him. Through diplomatic channels, his father Domenico is reached who, unaware of what happened, tracks down his son asking:
https://en.wikipedia.org/wiki?curid=34434541
2,089,156
718,922
Bion would speak of "an intense catastrophic emotional explosion O," which could only be known through its aftereffects. Where before he had privileged the domain of knowledge (K), now he would speak as well of "resistance to the shift from transformations involving K (knowledge) to transformations involving O ... resistance to the unknowable". Hence his injunctions to the analyst to eschew memory and desire, to "bring to bear a diminution of the 'light' – a penetrating beam of darkness; a reciprocal of the searchlight. If any object existed, however faint, it would show up very clearly". In stating this he was making connections to Freud, who in a letter to Lou Andreas Salome had referred to a mental counterpart of scotopic, "mole like vision", used to gain impressions of the Unconscious. He was also making links with the "apophatic" method used by contemplative thinkers such as St John of the Cross, a writer quoted many times by Bion. Bion was well aware that our perception and our attention often blind us to what genuinely and strikingly is new in every moment.
https://en.wikipedia.org/wiki?curid=44779
718,542
2,041,076
Hutsonville Power Station came online in 1940 generating 31 megawatts (MW) of electricity. Unit 2 came online the following year and Units 3 and 4 came online in 1953 and 1954 respectively. Units 1 and 2 were decommissioned in 1981. At the time of its closure, Hutsonville had two active units generating a combined 151 MW. Coal used to generate electricity was extracted at nearby coal mines in Illinois and Indiana until 2006. In 2004, Hutsonville began the transition to burning coal delivered from the Powder River Basin. Towards the end of its useful life, Hutsonville generated electricity sporadically as it was one of Ameren's least efficient power plants. Rather than complying to the Environmental Protection Agency's (EPA) Cross-State Air Pollution Rule, Ameren announced they would close Hutsonville by the end of 2011. In early 2015, Ameren demolished Hutsonville following three years of decommissioning.
https://en.wikipedia.org/wiki?curid=55607537
2,039,896
577,853
During July 2012, the company announced that 700 hours of flight testing had been completed, during which the prototypes had attained a top speed of Mach 0.56 ( true airspeed) along with 30,000 pressurization cycles on a test fuselage. Around this time, a set of winglets were installed upon the prototype with the aim of improving roll control throughout the entirety of its speed range, especially during stall conditions. Following this addition, the design was frozen and the company proceeded to commence the construction of production tooling for the fourth serial aircraft. At this time, certification of the D-JET was forecast to occur during late 2013, while the first deliveries of production aircraft were to commence during the third quarter of 2014.
https://en.wikipedia.org/wiki?curid=8087203
577,557
558,063
The possibility of anaesthesia by the inert gas argon in particular (even at 10 to 15 bar) suggests that the mechanism of action of volatile anaesthetics is an effect best described by physical chemistry, and not a chemical bonding action. However, the agent may bind to a receptor with a weak interaction. A physical interaction such as swelling of nerve cell membranes from gas solution in the lipid bilayer may be operative. Notably, the gases hydrogen, helium, and neon have not been found to have anaesthetic properties at any pressure. Helium at high pressures produces nervous irritation ("anti-anaesthesia"), suggesting that the anaesthetic mechanism(s) may be operated in reverse by this gas (i.e., nerve membrane compression). Also, some halogenated ethers (such as flurothyl) also possess this "anti-anaesthetic" effect, providing further evidence for this theory.
https://en.wikipedia.org/wiki?curid=1331702
557,774
1,297,811
As an adaptation strategy to improve income of fishermen and to help them cope up with adverse climatic events, the ICAR-Central Marine Fisheries Research Institute(CMFRI) developed a multivendor E-commerce website and associated android app (marinefishsales) through the National Innovations on Climate Resilient Agriculture (NICRA) project. The website and mobile app is aimed at helping fish farmers and fishermen to sell their farmed fish and marine catch directly to the customers online and to fetch better income without depending middlemen. Various fishermen SHGs can register as vendors (fishers and farmers) based on their fish products and update their stock availability under pre-approved categories and products, which shall be displayed in the website and associated mobile app. Customers visiting the website or app could place the order and subsequently the registered fisher/farmer shall be notified through email and SMS, upon which the quality products within the pre-assigned time frame shall be delivered, enabling direct product sale between customers and SHGs.
https://en.wikipedia.org/wiki?curid=5116330
1,297,099
132,343
A mental state, or a mental property, is a state of mind of a person. Mental states comprise a diverse class, including perception, pain experience, belief, desire, intention, emotion, and memory. There is controversy concerning the exact definition of the term. According to "epistemic approaches", the essential mark of mental states is that their subject has privileged epistemic access while others can only infer their existence from outward signs. "Consciousness-based approaches" hold that all mental states are either conscious themselves or stand in the right relation to conscious states. "Intentionality-based approaches", on the other hand, see the power of minds to refer to objects and represent the world as the mark of the mental. According to "functionalist approaches", mental states are defined in terms of their role in the causal network independent of their intrinsic properties. Some philosophers deny all the aforementioned approaches by holding that the term "mental" refers to a cluster of loosely related ideas without an underlying unifying feature shared by all. Various overlapping classifications of mental states have been proposed. Important distinctions group mental phenomena together according to whether they are "sensory", "propositional", "intentional", "conscious" or "occurrent". Sensory states involve sense impressions like visual perceptions or bodily pains. Propositional attitudes, like beliefs and desires, are relations a subject has to a proposition. The characteristic of intentional states is that they refer to or are about objects or states of affairs. Conscious states are part of the phenomenal experience while occurrent states are causally efficacious within the owner's mind, with or without consciousness. An influential classification of mental states is due to Franz Brentano, who argues that there are only three basic kinds: presentations, judgments, and phenomena of love and hate.
https://en.wikipedia.org/wiki?curid=2075414
132,291
442,312
The Mutazilities, compelled to defend their principles against the orthodox Islam of their day, looked for support in philosophy, and are one of the first to pursue a rational theology called "Ilm-al-Kalam" (Scholastic theology); those professing it were called "Mutakallamin". This appellation became the common name for all seeking philosophical demonstration in confirmation of religious principles. The first Mutakallamin had to debate both the orthodox and the non-Muslims, and they may be described as occupying the middle ground between those two parties. But subsequent generations were to large extent critical towards the Mutazilite school, especially after formation of the Asharite concepts. Throughout history, the place of kalam in Islamic thought has been controversial. The vast majority of the early traditional Sunni Muslim scholars have either criticized or prohibited it. Jewish and Muslim Peripatetics, generally, stopped short in their respective Aristotelianism whenever there was danger of wounding orthodox religion.
https://en.wikipedia.org/wiki?curid=171177
442,097
538,285
While many characterization techniques have been practiced for centuries, such as basic optical microscopy, new techniques and methodologies are constantly emerging. In particular the advent of the electron microscope and secondary ion mass spectrometry in the 20th century has revolutionized the field, allowing the imaging and analysis of structures and compositions on much smaller scales than was previously possible, leading to a huge increase in the level of understanding as to why different materials show different properties and behaviors. More recently, atomic force microscopy has further increased the maximum possible resolution for analysis of certain samples in the last 30 years.
https://en.wikipedia.org/wiki?curid=4932763
538,006