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The source of Einstein's proposal that light was composed of particles (or could act as particles in some circumstances) was an experimental anomaly not explained by the wave theory: the photoelectric effect, in which light striking a metal surface ejected electrons from the surface, causing an electric current to flow across an applied voltage. Experimental measurements demonstrated that the energy of individual ejected electrons was proportional to the "frequency", rather than the "intensity", of the light. Furthermore, below a certain minimum frequency, which depended on the particular metal, no current would flow regardless of the intensity. These observations appeared to contradict the wave theory, and for years physicists tried in vain to find an explanation. In 1905, Einstein explained this puzzle by resurrecting the particle theory of light to explain the observed effect. Because of the preponderance of evidence in favor of the wave theory, however, Einstein's ideas were met initially with great skepticism among established physicists. Eventually Einstein's explanation was accepted as new particle-like behavior of light was observed, such as the Compton effect.
https://en.wikipedia.org/wiki?curid=9426
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Paul Erdős, Chao Ko, and Richard Rado proved this theorem in 1938 after working together on it in England. Rado had moved from Berlin to the University of Cambridge and Erdős from Hungary to the University of Manchester, both escaping the influence of Nazi Germany; Ko was a student of Louis J. Mordell at However, they did not publish the result with the long delay occurring in part because of a lack of interest in combinatorial set theory in the 1930s, and increased interest in the topic in The 1961 paper stated the result in an apparently more general form, in which the subsets were only required to be size and to satisfy the additional requirement that no subset be contained in any A family of subsets meeting these conditions can be enlarged to subsets of size either by an application of or by choosing each enlarged subset from the same chain in a symmetric chain decomposition
https://en.wikipedia.org/wiki?curid=296188
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McClintock received a fellowship from the Guggenheim Foundation that made possible six months of training in Germany during 1933 and 1934. She had planned to work with Curt Stern, who had demonstrated crossing-over in "Drosophila" just weeks after McClintock and Creighton had done so; however, Stern emigrated to the United States. Instead, she worked with geneticist Richard B. Goldschmidt, who was a director of the Kaiser Wilhelm Institute for Biology in Berlin. She left Germany early amidst mounting political tension in Europe, and returned to Cornell, remaining there until 1936, when she accepted an Assistant Professorship offered to her by Lewis Stadler in the Department of Botany at the University of Missouri in Columbia. While still at Cornell, she was supported by a two-year Rockefeller Foundation grant obtained for her through Emerson's efforts.
https://en.wikipedia.org/wiki?curid=55188
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There are two space toilets on the ISS, both of Russian design, located in "Zvezda" and "Tranquility". These Waste and Hygiene Compartments use a fan-driven suction system similar to the Space Shuttle Waste Collection System. Astronauts first fasten themselves to the toilet seat, which is equipped with spring-loaded restraining bars to ensure a good seal. A lever operates a powerful fan and a suction hole slides open: the air stream carries the waste away. Solid waste is collected in individual bags which are stored in an aluminium container. Full containers are transferred to Progress spacecraft for disposal. Liquid waste is evacuated by a hose connected to the front of the toilet, with anatomically correct "urine funnel adapters" attached to the tube so that men and women can use the same toilet. The diverted urine is collected and transferred to the Water Recovery System, where it is recycled into drinking water. In 2021, the arrival of the Nauka module also brought a third toilet to the ISS.
https://en.wikipedia.org/wiki?curid=15043
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Morrison had a secret basement laboratory in downtown Des Moines where he worked on storage batteries and a self-propelled electric carriage. He referred to it as "the Cave". He constructed a prototype of the first electric carriage in 1887. Morrison had a mechanical engineer, Dr. Lew Arntz, working with him who assembled what he designed. Between 1888 and 1890 Morrison designed a second version of his electric carriage which had improvements in its electric motor, gear train, batteries and steering mechanism. The modifications made his carriage practical and useful and is the one that became famous—the first practical electric automobile built in the United States. To demonstrate the usefulness of Morrison's invention, the vehicle was entered into the 1890 Seni Om Sed parade in Des Moines where there were 85,000 to 100,000 spectators. The battery-powered vehicle was carrying seven passengers. The chemist drove his electric automobile all over the city for weeks after the parade. It was in several notable races. The spectacle of the first practical automobile being on the streets of Des Moines was written up in multiple newspapers and journals. Word spread worldwide of the carriage that required no horses and was mobile under its own power. Before the end of the year Morrison had received over 16,000 letters requesting information on his self-powered electric carriage (auto-mobile).
https://en.wikipedia.org/wiki?curid=63019379
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The role of confirmatory electrodiagnostic testing is debated. The goal of electrodiagnostic testing is to compare the speed of conduction in the median nerve with conduction in other nerves supplying the hand. When the median nerve is compressed, as in IMNCT, it will conduct more slowly than normal and more slowly than other nerves. Compression results in damage to the myelin sheath and manifests as delayed latencies and slowed conduction velocities. There are many electrodiagnostic tests used to make a diagnosis of CTS, but the most sensitive, specific, and reliable test is the Combined Sensory Index (also known as the Robinson index). Electrodiagnosis rests upon demonstrating impaired median nerve conduction across the carpal tunnel in context of normal conduction elsewhere. It is often stated that normal electrodiagnostic studies do not preclude the diagnosis of carpal tunnel syndrome. The rational for this is that a threshold of neuropathy must be reached before study results become abnormal and also that threshold values for abnormality vary. Others contend that idiopathic median neuropathy at the carpal tunnel with normal electrodiagnostic tests would represent very, very mild neuropathy that would be best managed as a normal median nerve. Even more important, notable symptoms with mild disease is strongly associated with unhelpful thoughts and symptoms of worry and despair. Notable CTS with unmeasurable IMNCT should remind clinicians to always consider the whole person, including their mindset and circumstances, in strategies to help people get and stay healthy.
https://en.wikipedia.org/wiki?curid=56462
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On the first day of competition on July 24, four finals were contested, the women's and men's 400 m freestyle and women's and men's 4×100 m freestyle relay. In the women's 400 m freestyle, Italian Federica Pellegrini successfully defended her 2009 crown and crushed the field to win gold in a time of 4:01.97, over two seconds ahead of British Rebecca Adlington. In the men's 400 m freestyle, Korean Park Tae-Hwan won the gold in a time of 3:42.04, over one second ahead of second-place finisher Chinese Sun Yang. After the 400 m freestyle event was the women's and men's 4×100 m freestyle relay. In the women's 4×100 m freestyle relay, the Dutch team of Inge Dekker, Ranomi Kromowidjojo, Marleen Veldhuis, and Femke Heemskerk finished ahead of the United States 3:33.96 to 3:34.47. Because of Heemskerk's 100 m split of 52.46, the Dutch were able to overcome the United States on the final leg. Next in the men's 4×100 m freestyle relay, the Australian team of James Magnussen, Matthew Targett, Matthew Abood, and Eamon Sullivan won the gold in a time of 3:11.00. Magnussen jolted the Australians ahead in the first leg with a split of 47.49. American Michael Phelps (whose team finished third) had the second-best start with a 48.08. After the race, Phelps said of Magnussen, "He's talented, he's young. I think it's going to make it exciting for the sport and add something else to that relay, that's for sure." No new world or competition records were set during day one.
https://en.wikipedia.org/wiki?curid=4466178
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For example, PSI is investigating the structure of filamentous structures, the so-called microtubules, which, among other things, pull apart chromosomes during cell division. They consist of long protein chains. When chemotherapy is used to treat cancer, it disturbs the assembly or breakdown of these chains so that the cancer cells can no longer divide. Researchers are closely observing the structure of these proteins and how they change to find out exactly where cancer drugs have to attack the microtubules. With the help of PSI's SwissFEL free-electron X-ray laser, which was inaugurated in 2016, researchers have been able to analyse dynamic processes in biomolecules with extremely high time resolution – less than a trillionth of a second (picosecond). For example, they have detected how certain proteins in the photoreceptors of the retina of our eyes are activated by light.
https://en.wikipedia.org/wiki?curid=1053016
1,046,642
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Les Solomon, the Technical Editor of "Popular Electronics", liked to meet the magazine's authors. When he was on vacation in 1970, he visited Forrest Mims and Ed Roberts in New Mexico. Solomon gave them advice on selling project kits such as the "Opticom LED Communicator" but Mims was really interested in becoming a full-time writer. Solomon explained the magazine publishing business and helped Mims get articles placed in "Popular Electronics". Mims also wrote for other magazines; "Experiment With a $32 Solid State Laser" was featured on the June 1972, cover of "Radio-Electronics." In October 1975, Mims convinced Art Salsberg, Editor of "Popular Electronics", to offer him a monthly column, the "Experimenter's Corner". He later added two additional columns, "Project of the Month" and "Solid-State Developments". Mims wrote for this magazine until it ceased publication in April 1985. Meanwhile, Salsberg had started another hobbyist magazine, "Modern Electronics"; and Mims wrote a monthly column and was a contributing editor.
https://en.wikipedia.org/wiki?curid=1527744
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In April 2005, an Asia-1 strain of FMD appeared in the eastern provinces of Shandong and Jiangsu. During April and May, it spread to suburban Beijing, the northern province of Hebei, and the Xinjiang autonomous region in northwest China. On 13 May, China reported the FMD outbreak to the World Health Organization and the OIE. This was the first time China has publicly admitted to having FMD. China is still reporting FMD outbreaks. In 2007, reports filed with the OIE documented new or ongoing outbreaks in the provinces of Gansu, Qinghai and Xinjiang. This included reports of domestic yak showing signs of infection. FMD is endemic in pastoral regions of China from Heilongjiang Province in the northeast to Sichuan Province and the Tibetan Autonomous region in the southwest. Chinese domestic media reports often use a euphemism "Disease Number Five" (五号病 "wǔhàobìng") rather than FMD in reports because of the sensitivity of the FMD issue. In March 2010, "Southern Rural News" ("Nanfang Nongcunbao"), in an article "Breaking the Hoof and Mouth Disease Taboo", noted that FMD has long been covered up in China by referring to it that way. FMD is also called canker (口疮, literally "mouth ulcers" "kǒuchuāng") or hoof jaundice (蹄癀 "tíhuáng") in China, so information on FMD in China can be found online using those words as search terms. One can find online many provincial orders and regulations on FMD control antedating China's acknowledgment that the disease existed in China, for example Guangxi Zhuang Autonomous Region 1991 regulation on preventing the spread of Disease No.5.
https://en.wikipedia.org/wiki?curid=21438755
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Children with HLHS and other comparable single-ventricle conditions, as a group, have poorer neurodevelopmental outcomes than their healthy peers. Deficits in language, executive functioning, and higher rates of anxiety and depression disorders have been demonstrated. Some of these outcomes may be a consequence of genetic factors associated with HLHS, and others may be modifiable through changes to procedures and to the healthcare environment. There is an emerging clinical consensus around the importance of continuous neurodevelopmental surveillance from the earliest years into adulthood. Additionally, a recent meta-analysis comparing twenty-two studies showed that 64.7% of the studies reported delayed motor development in children with single ventricle physiologies, such as hypoplastic left heart syndrome.
https://en.wikipedia.org/wiki?curid=1797918
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Apart from a few springs, some of them low-flowing, the whole site of Petra is devoid of perennial water flows, not sufficient for the needs of a city that kept expanding for nearly a millennium. Charles Ortloff, an archaeologist from the University of Chicago, estimates that at its peak, the urban population of Petra reached 30,000. "..."We must therefore appeal to human constructions so that life becomes possible in a natural environment where there is a lack of water on the surface"..." . Petra receives significant quantities of rainwater for several months each year, which resulted in the construction of hydraulic installations to allow the capture of the rainwater, its storage and its distribution of in order to provide for the needs of the city.
https://en.wikipedia.org/wiki?curid=42585943
1,375,169
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Once created, the Meiji military machine was used to extend Japanese power overseas, for many leaders believed that national security depended on expansion and not merely a strong defense. Room was also needed for population expansion. Within thirty years, the country's military forces had fought and defeated imperial China in the First Sino-Japanese War (1894–95), winning possession of Taiwan and China's recognition of Korea's independence. Ten years later, in the Russo-Japanese War (1904–5), Japan defeated tsarist Russia and won possession of southern Sakhalin as well as a position of paramount influence in Korea and southern Manchuria. By this time, Japan had been able to negotiate revisions of the unequal treaties with the Western powers and had in 1902 formed an alliance with the world's leading power, Britain.
https://en.wikipedia.org/wiki?curid=2998679
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In October 1941, Mediterranean Command asked for some solution to the problem of detecting Italian human torpedoes which were attacking ships in Gibraltar and Alexandria. A modified version of the Type 273 was provided, removing the stabilization system (not needed on land) and further increasing the reflectors to which improved gain to 575. Several such systems were built under the name Types 273S (for Shore) and delivered in 1942. A further one-off modification was made for the site at Saebol, Iceland, due to the high winds at that location. This Type 273M was mounted on a gun mount for extra stability. In testing on 29 September 1942, the 273M demonstrated a range against a trawler from its high location, which is only slightly short of the radar horizon of .
https://en.wikipedia.org/wiki?curid=39752340
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For example, in the nuclear genome of Drosophila melanogaster, one study placed the rate of single-nucleotide mutation at 3.5 × 10 mutations per site per generation, while another study obtained a value of 5.8 × 10 mutations per site per generation for the same parameter. Estimates of the D. melanogaster mitochondrial genome mutation rate are generally ~10 times higher than that of the nuclear genome, with one estimate being 6.2 x 10 mutations per site per generation. The rate of occurrence for deleterious mutations per generation (Ud) can be obtained by multiplying the average number of mutations per generation by the proportion of mutations which are expected to be deleterious within a given species. However, it can also be estimated by way of fitness assays using MA lines of known genotype. In Drosophila melanogaster, one study placed the value of this parameter at 1.2 deleterious mutations per diploid genome per generation, which matches closely the average value of this parameter within this species across all studies on the subject conducted as of 1999. However, the putative Ud values obtained by way of similar mutation accumulation-based studies have varied significantly, with some estimates being as low as 0.02 deleterious mutations per diploid genome per generation, a value not much higher than the putative lethal mutation rate of 0.01 mutations per generation. Uncharacteristically low values such as this are usually obtained in studies that classify mutations as either deleterious or not by screening for quantifiable decreases in viability. This is because these studies are thought to overlook the vast majority of deleterious mutations for which the overall effect on viability is too small in magnitude to be observed by way of such assays. Higher Ud values (>1) that are more in line with current scientific consensus regarding the estimation of this parameter in D. melanogaster suggest that selection against these deleterious mutations may play a significant role in shaping patterns of genetic variation in the genome, as well as in maintaining selection for recombination and sexual reproduction.
https://en.wikipedia.org/wiki?curid=63668207
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In 1953, Bohlin named these as the type species "Heishansaurus pachycephalus". The generic name refers to the Heishan, the "Black Mountains". The specific name "pachycephalus", meaning "thick-headed", was inspired by Bohlin's identification of the taxon as a pachycephalosaur. Today this dinosaur is more probably considered an ankylosaur. The fossils, from the Minhe Formation dating from the Late Cretaceous (Campanian or Maastrichtian stage), were fragmentary. The type is the only known specimen. The material consisted of poorly preserved cranial and postcranial fragments plus some dermal scutes. It contained skull fragments including a maxilla, teeth, vertebrae from the neck, back and tail, osteoderms and spikes. Today, the specimen is lost. Of one dorsal vertebra a cast remains, preserved in the American Museum of Natural History with the inventory number AMNH 2062.
https://en.wikipedia.org/wiki?curid=4575108
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The Time Stamp Counter was once an excellent high-resolution, low-overhead way for a program to get CPU timing information. With the advent of multi-core/hyper-threaded CPUs, systems with multiple CPUs, and hibernating operating systems, the TSC cannot be relied upon to provide accurate results — unless great care is taken to correct the possible flaws: rate of tick and whether all cores (processors) have identical values in their time-keeping registers. There is no promise that the timestamp counters of multiple CPUs on a single motherboard will be synchronized. Therefore, a program can get reliable results only by limiting itself to run on one specific CPU. Even then, the CPU speed may change because of power-saving measures taken by the OS or BIOS, or the system may be hibernated and later resumed, resetting the TSC. In those latter cases, to stay relevant, the program must re-calibrate the counter periodically.
https://en.wikipedia.org/wiki?curid=4538483
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Pillars are a major part of Western Chalukya architecture and were produced in two main types: pillars with alternate square blocks and a sculptured cylindrical section with a plain square-block base, and bell-shaped lathe-turned pillars. The former type is more vigorous and stronger than the bell-shaped type, which is made of soapstone and has a quality of its own. Inventive workmanship was used on soapstone shafts, roughly carved into the required shapes using a lathe. Instead of laboriously rotating a shaft to obtain the final finish, workers added the final touches to an upright shaft by using sharp tools. Some pillars were left unpolished, as evidenced by the presence of fine grooves made by the pointed end of the tool. In other cases, polishing resulted in pillars with fine reflective properties such as the pillars in the temples at Bankapura, Itagi and Hangal. This pillar art reached its zenith in the temples at Gadag, specifically the Sarasvati Temple in Gadag city.
https://en.wikipedia.org/wiki?curid=13931173
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Governmental organizations can often be resistant or glacially slow to change along with social and technological transformation. Even when evidence of malfunction is clear this form of institutional inertia can persist. Political scientist Francis Fukuyama has asserted that humans imbue intrinsic value on the rules they enact and follow, especially in the larger societal institutions that create order and stability. Despite rapid social change and increasing institutional problems, the value placed on an institution and its rules can mask how well an institution is functioning as well as how that institution could be improved. The inability to change an institutional mindset is supported by the theory of punctuated equilibrium, long periods of deleterious governmental policies punctuated by moments of civil unrest. After decades of economic decline the United Kingdom's referendum to leave to EU was seen as an example of the dramatic movement after a long period of governmental inertia.
https://en.wikipedia.org/wiki?curid=24200321
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Cortical learning algorithms are able to learn continuously from each new input pattern, therefore no separate inference mode is necessary. During inference, HTM tries to match the stream of inputs to fragments of previously learned sequences. This allows each HTM layer to be constantly predicting the likely continuation of the recognized sequences. The index of the predicted sequence is the output of the layer. Since predictions tend to change less frequently than the input patterns, this leads to increasing temporal stability of the output in higher hierarchy levels. Prediction also helps to fill in missing patterns in the sequence and to interpret ambiguous data by biasing the system to infer what it predicted.
https://en.wikipedia.org/wiki?curid=11273721
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The UueF molecule is expected to have a significant covalent character owing to the high electron affinity of ununennium. The bonding in UueF is predominantly between a 7p orbital on ununennium and a 2p orbital on fluorine, with lesser contributions from the 2s orbital of fluorine and the 8s, 6d, and the two other 7p orbitals of ununennium. This is very different from the behaviour of s-block elements, as well as gold and mercury, in which the s-orbitals (sometimes mixed with d-orbitals) are the ones participating in the bonding. The Uue–F bond is relativistically expanded due to the splitting of the 7p orbital into 7p and 7p spinors, forcing the bonding electrons into the largest orbital measured by radial extent: a similar expansion in bond length is found in the hydrides AtH and TsH. The Uue–Au bond should be the weakest of all bonds between gold and an alkali metal, but should still be stable. This gives extrapolated medium-sized adsorption enthalpies (−Δ"H") of 106 kJ/mol on gold (the francium value should be 136 kJ/mol), 76 kJ/mol on platinum, and 63 kJ/mol on silver, the smallest of all the alkali metals, that demonstrate that it would be feasible to study the chromatographic adsorption of ununennium onto surfaces made of noble metals. The enthalpy of adsorption of ununennium on a Teflon surface is predicted to be 17.6 kJ/mol, which would be the lowest among the alkali metals: this information would be very useful for future chemistry experiments on ununennium. The Δ"H" and −Δ"H" values for the alkali metals change in opposite directions as atomic number increases.
https://en.wikipedia.org/wiki?curid=67492
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Roderick I. Sutherland at the University in Sydney has a Lagrangian formalism for the pilot wave and its beables. It draws on Yakir Aharonov's retrocasual weak measurements to explain many-particle entanglement in a special relativistic way without the need for configuration space. The basic idea was already published by Costa de Beauregard in the 1950s and is also used by John Cramer in his transactional interpretation except the beables that exist between the von Neumann strong projection operator measurements. Sutherland's Lagrangian includes two-way action-reaction between pilot wave and beables. Therefore, it is a post-quantum non-statistical theory with final boundary conditions that violate the no-signal theorems of quantum theory. Just as special relativity is a limiting case of general relativity when the spacetime curvature vanishes, so, too is statistical no-entanglement signaling quantum theory with the Born rule a limiting case of the post-quantum action-reaction Lagrangian when the reaction is set to zero and the final boundary condition is integrated out.
https://en.wikipedia.org/wiki?curid=54717
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The "Great Illyrian Revolt", ("Bellum Batonianum" or "Pannonian Revolt") was a major conflict between an alliance of Illyrian communities and the Roman forces that lasted for four years beginning in AD 6 and ending in AD 9. In AD 6, several regiments of Daesitiates, natives of area that now comprises central Bosnia and Herzegovina, led by Bato the Daesitiate (Bato I), were gathered in one place to prepare to join Augustus's stepson and senior military commander Tiberius in a war against the Germans. Instead, the Daesitiates mutinied and defeated a Roman force sent against them. The Daesitiates were soon joined by the Breuci led by Bato of the Breuci (Bato II), another community inhabiting the region between the rivers Sava and Drava in modern Croatia. They gave battle to a second Roman force from Moesia led by Caecina Severus (the governor of Moesia). Despite their defeat, they inflicted heavy casualties at the Battle of Sirmium. The rebels were now joined by a large number of other communities. At risk was the strategic province of Illyricum, recently expanded to include the territory of the Pannonii, an indigenous communities inhabiting the region between the rivers Drava and Sava, who were subjugated by Rome in 12–9 BC. Illyricum was on Italy's eastern flank, exposing the Roman heartland to the fear of a rebel invasion.
https://en.wikipedia.org/wiki?curid=16052796
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The head of the Government was the king, a hereditary monarch. His power was restricted by the "Aimberunguzhu" (Tamil: ஐம்பெருங்குழு) or the Five Great Assemblies, which consisted of the representatives of the people, priests, physicians, astrologers and the ministers. There was another assembly of officials that served the king called the "Enberaayam" (Tamil: எண்பேராயம்) or the Eight Groups of Attendants. While some scholars believe it consisted of attendants on the king's person like the perfumers, dressing valets, etc., others believe it consisted of more important persons like the people of the capital city, the leaders of the elephant corps and of the cavalry. The principal officers of State were the high priest, the chief astrologer, the ministers and the commanders of the army. The king divided his territory into a number of administrative units or principalities, each called a "Kootram" (Tamil: கூற்றம்). A "Kootram" was further divided into provinces called "Mandalam", which in turn was divided into many sub-provinces called "Nadus", with each "Nadu" consisting of many villages. A locality inside a town or village was called "Ur" and each neighborhood inside an "Ur" was called a "Cheri". While the king ruled over his entire territory from the capital, he often placed one or more principalities ("Kootram") under the near-sovereign government of some senior member of the royal family or a feudatary. The village was the most fundamental unit of administration under the Pandyas. The affairs of a village were the responsibility of its elders, who supervised the judicial, administrative and financial functions.
https://en.wikipedia.org/wiki?curid=11673386
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Many commercially manufactured bottles contain a resin that absorbs antibiotics to reduce their action on the microorganisms in the sample. Bottles intended for pediatric use are designed to accommodate lower blood volumes and have additives that enhance the growth of pathogens more commonly found in children. Other specialized bottles may be used to detect fungi and mycobacteria. In low and middle income countries, pre-formulated culture bottles can be prohibitively expensive, and it may be necessary to prepare the bottles manually. It can be difficult to access the proper supplies and facilities, and in some regions, it may not be possible to perform blood cultures at all.
https://en.wikipedia.org/wiki?curid=1250090
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Economic development in Mumbai brought a growth in population caused mainly by the migration of laborers from other regions of the country. The number of residents in the city increased more than twelve times in the last century. Greater Mumbai, formed by City Island and Salsette Island, is the largest city in India with a population of 16.4 million, according to data collected by the census of 2001. Mumbai is one of the densest cities in the world, 48,215 persons per km² and 16,082 per km² in suburban areas. In this scenario, urban agriculture seems unlikely to be put into practice since it must compete with real estate developers for the access and use of vacant lots. Alternative farming methods have emerged as a response to the scarcity of land, water, and economic resources employed in UPA.
https://en.wikipedia.org/wiki?curid=450257
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In these studies, the goal usually is to diagnose a disease (or a sub-class of a disease) using variations in one or more cell populations. For example, one can use multidimensional clustering to identify a set of clusters, match them across all samples, and then use supervised learning to construct a classifier for prediction of the classes of interest (e.g., this approach can be used to improve the accuracy of the classification of specific lymphoma subtypes). Alternatively, all the cells from the entire cohort can be pooled into a single multidimensional space for clustering before classification. This approach is particularly suitable for datasets with a high amount of biological variation (in which cross-sample matching is challenging) but requires technical variations to be carefully controlled.
https://en.wikipedia.org/wiki?curid=41282920
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Radiant cooling systems offer lower energy consumption than conventional cooling systems based on research conducted by the Lawrence Berkeley National Laboratory. Radiant cooling energy savings depend on the climate, but on average across the US savings are in the range of 30% compared to conventional systems. Cool, humid regions might have savings of 17% while hot, arid regions have savings of 42%. Hot, dry climates offer the greatest advantage for radiant cooling as they have the largest proportion of cooling by way of removing sensible heat. While this research is informative, more research needs to be done to account for the limitations of simulation tools and integrated system approaches. Much of the energy savings is also attributed to the lower amount of energy required to pump water as opposed to distribute air with fans. By coupling the system with building mass, radiant cooling can shift some cooling to off-peak night time hours. Radiant cooling appears to have lower first costs and lifecycle costs compared to conventional systems. Lower first costs are largely attributed to integration with structure and design elements, while lower life cycle costs result from decreased maintenance. However, a recent study on comparison of VAV reheat versus active chilled beams & DOAS challenged the claims of lower first cost due to added cost of piping
https://en.wikipedia.org/wiki?curid=41114338
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The numerical solution of the Richards equation is one of the most challenging problems in earth science. Richards' equation has been criticized for being computationally expensive and unpredictable because there is no guarantee that a solver will converge for a particular set of soil constitutive relations. Advanced computational and software solutions are required here to over-come this obstacle. The method has also been criticized for over-emphasizing the role of capillarity, and for being in some ways 'overly simplistic' In one dimensional simulations of rainfall infiltration into dry soils, fine spatial discretization less than one cm is required near the land surface, which is due to the small size of the representative elementary volume for multiphase flow in porous media. In three-dimensional applications the numerical solution of the Richards equation is subject to aspect ratio constraints where the ratio of horizontal to vertical resolution in the solution domain should be less than about 7.
https://en.wikipedia.org/wiki?curid=7153598
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In 1943, Zadeh decided to leave for the United States to continue his education. He travelled to Philadelphia by way of Cairo after months of delay waiting first for the proper papers and later for the right ship to appear. He arrived in mid-1944, lived in New York and worked for an electronic association, and entered the Massachusetts Institute of Technology (MIT) as a graduate student in September that year. While in the United States, he shortened his family name, creating a new middle name from the part he removed, and was thenceforth known as Lotfi Aliasker Zadeh. He received an MS degree in electrical engineering from MIT in 1946.
https://en.wikipedia.org/wiki?curid=201155
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In 1993, a heritable resistance to APC was detected by Dahlbäck "et al." and associated with familial thrombophilia. In 1994, the relatively common genetic mutation that produces Factor V was noted (Bertina "et al."). Two years later, Gla-domainless APC was imaged at a resolution of 2.8 Ångströms. Beginning with the PROWESS clinical trial of 2001, it was recognised that many of the symptoms of sepsis may be ameliorated by infusion of APC, and mortality rates of septic patients may be significantly decreased. Near the end of that year, Drotrecogin alfa (activated), a recombinant human activated protein C, became the first drug approved by the U.S. FDA for treating severe sepsis. In 2002, "Science" published an article that first showed protein C activates protease-activated receptor-1 (PAR-1) and this process accounts for the protein's modulation of the immune system.
https://en.wikipedia.org/wiki?curid=1364354
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According to the ecological model, it is more appropriate to model the economy on biology (growth, change, death, evolution, survival of the fittest, complex inter-relationships, non-linear relationships). Businesses operate in a complex environment with interlinked sets of determinants. Companies co-evolve: they influence, and are influenced by, competitors, customers, governments, investors, suppliers, unions, distributors, banks, and others. We should look at this business environment as a business ecosystem that both sustains, and threatens the firm. A company that is not well matched to its environment might not survive. Companies that are able to develop a successful business model and turn a core competency into a sustainable competitive advantage will thrive and grow. Very successful firms may come to dominate their industry (referred to as "category killers").
https://en.wikipedia.org/wiki?curid=252969
1,838,459
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Although Chomsky's theory of a generative grammar has been enormously influential in the field of linguistics since the 1950s, many criticisms of the basic assumptions of generative theory have been put forth by cognitive-functional linguists, who argue that language structure is created through language use. These linguists argue that the concept of a language acquisition device (LAD) is unsupported by evolutionary anthropology, which tends to show a gradual adaptation of the human brain and vocal cords to the use of language, rather than a sudden appearance of a complete set of binary parameters delineating the whole spectrum of possible grammars ever to have existed and ever to exist. On the other hand, cognitive-functional theorists use this anthropological data to show how human beings have evolved the capacity for grammar and syntax to meet our demand for linguistic symbols. (Binary parameters are common to digital computers, but may not be applicable to neurological systems such as the human brain.)
https://en.wikipedia.org/wiki?curid=18614
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Thomas J. Oxley is the chief executive officer of Synchron and neurointerventionist at Mount Sinai Hospital in New York City. Trained as a vascular and interventional neurologist, he established the Vascular Bionics laboratory at the University of Melbourne and is currently co-head of this lab. Oxley is best known for founding Synchron, a company building next-generation brain computer interface solutions that has recently announced the first clinical data on a novel stent electrode (Stentrode) neural interface that is inserted through blood vessels. The company was initiated sometime after his cold-call to DARPA for funding, and has received substantial funding from the U.S. Defense Advanced Research Projects Agency (DARPA) and the Australian government to research this minimally-invasive neural interface technology.
https://en.wikipedia.org/wiki?curid=61159719
1,277,581
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The JMSDF has equipped four ships of the "Kongo"-class destroyers for LRST and engagement: , , , and the (in 2010). Japan's foreign minister, Hirofumi Nakasone and South Korea's Minister of Foreign Affairs, Yu Myung-hwan, agreed that early April 5, 2009, launch of the North Korean Unha-2 satellite violated UN resolutions 1695 and 1718 of July 2006. Japan's cabinet examined approval of a JMSDF AEGIS BMD engagement in the event of a failure of the Taepondong launch. The Japanese government also noted that it could bypass cabinet for an interception under Article 82, Section 2, Paragraph 3 of the Self-Defence Forces law. In total, five AEGIS destroyers were deployed at that time. Supplemental to SM-3 capability the Japanese system incorporates an airborne component. Together discrimination between platform tests and satellite launches is possible by analyzing the angle of ascent.
https://en.wikipedia.org/wiki?curid=249526
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Widlar was a hard person to work with, but the few men and women who could, like Talbert and Jack Gifford, joined his inner circle for life. Widlar and Talbert closely guarded their trade secrets and kept unwanted co-workers out of the loop. Gifford, one of those accepted by Widlar and Talbert, said that Widlar "would almost talk to nobody and he would only talk to me on, you know, if I could get him in the right mood. And he was still secretive as hell". Talbert pushed Widlar's experimental orders through his plant at top speed, saving his partner four weeks on every batch at the expense of other orders. Former Fairchild photographer Richard Steinheimer said in 1995: "Talbert handling the fabrication and Widlar handling the design, they ruled the world and led the world in linear integrated circuits for a couple of decades." Fairchild executive Don Valentine said in 2004: "This was a phenomenal duo of highly eccentric – or whatever the word is beyond eccentric – individuals".
https://en.wikipedia.org/wiki?curid=3483624
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In 1920, Arthur Eddington suggested hydrogen-helium fusion could be the primary source of stellar energy. Quantum tunneling was discovered by Friedrich Hund in 1927, and shortly afterwards Robert Atkinson and Fritz Houtermans used the measured masses of light elements to show that large amounts of energy could be released by fusing small nuclei. Building on the early experiments in artificial nuclear transmutation by Patrick Blackett, laboratory fusion of hydrogen isotopes was accomplished by Mark Oliphant in 1932. In the remainder of that decade, the theory of the main cycle of nuclear fusion in stars was worked out by Hans Bethe. Research into fusion for military purposes began in the early 1940s as part of the Manhattan Project. Self-sustaining nuclear fusion was first carried out on 1 November 1952, in the Ivy Mike hydrogen (thermonuclear) bomb test.
https://en.wikipedia.org/wiki?curid=21544
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The RPV and Nuclear Steam Supply System (NSSS) have significant improvements, such as the substitution of RIPs, eliminating conventional external recirculation piping loops and pumps in the containment that in turn drive jet pumps producing forced flow in the RPV. RIPs provide significant improvements related to reliability, performance and maintenance, including a reduction in occupational radiation exposure related to containment activities during maintenance outages. These pumps are powered by wet-rotor motors with the housings connected to the bottom of the RPV and eliminating large diameter external recirculation pipes that are possible leakage paths. The 10 internal recirculation pumps are located at the bottom of the annulus downcomer region (i.e., between the core shroud and the inside surface of the RPV). Consequently, internal recirculation pumps eliminate all of the jet pumps in the RPV, all of the large external recirculation loop pumps and piping, the isolation valves and the large diameter nozzles that penetrated the RPV and needed to suction water from and return it to the RPV. This design therefore reduces the worst leak below the core region to effectively equivalent to a leak. The conventional BWR3-BWR6 product line has an analogous potential leak of 24 or more inches in diameter. A major benefit of this design is that it greatly reduces the flow capacity required of the ECCS.
https://en.wikipedia.org/wiki?curid=2239348
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The seven-member Board of Governors is the main governing body of the Federal Reserve System. It is charged with overseeing the 12 District Reserve Banks and with helping implement national monetary policy. Governors are appointed by the President of the United States and confirmed by the Senate for staggered, 14-year terms. By law, the appointments must yield a "fair representation of the financial, agricultural, industrial, and commercial interests and geographical divisions of the country", and as stipulated in the Banking Act of 1935, the Chairman and Vice Chairman of the Board are two of seven members of the Board of Governors who are appointed by the President from among the sitting Governors. As an independent federal government agency, the Board of Governors does not receive funding from Congress, and the terms of the seven members of the Board span multiple presidential and congressional terms. Members of the Board of Governors function mostly independently. The Board is required to make an annual report of operations to the Speaker of the U.S. House of Representatives. It also supervises and regulates the operations of the Federal Reserve Banks, and the U.S. banking system in general.
https://en.wikipedia.org/wiki?curid=26692249
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Field-effect LCDs are lightweight, compact, portable, cheap, more reliable, and easier on the eyes than CRT screens. LCD screens use a thin layer of liquid crystal, a liquid that exhibits crystalline properties. It is sandwiched between two glass plates carrying transparent electrodes. Two polarizing films are placed at each side of the LCD. By generating a controlled electric field between electrodes, various segments or pixels of the liquid crystal can be activated, causing changes in their polarizing properties. These polarizing properties depend on the alignment of the liquid-crystal layer and the specific field-effect used, being either Twisted Nematic (TN), In-Plane Switching (IPS) or Vertical Alignment (VA). Color is produced by applying appropriate color filters (red, green and blue) to the individual subpixels. LCD displays are used in various electronics like watches, calculators, mobile phones, TVs, computer monitors and laptops screens etc.
https://en.wikipedia.org/wiki?curid=293396
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During the Industrial Revolution, the faster pace of life and scheduling of shifts and public transportation like trains depended on the more accurate timekeeping made possible by the pendulum. Daily life was organized around the home pendulum clock. More accurate pendulum clocks, called "regulators", were installed in places of business and railroad stations and used to schedule work and set other clocks. The need for extremely accurate timekeeping in celestial navigation to determine longitude on ships during long sea voyages drove the development of the most accurate pendulum clocks, called "astronomical regulators". These precision instruments, installed in naval observatories and kept accurate within a second by observation of star transits overhead, were used to set marine chronometers on naval and commercial vessels. Beginning in the 19th century, astronomical regulators in naval observatories served as primary standards for national time distribution services that distributed time signals over telegraph wires. From 1909, US National Bureau of Standards (now NIST) based the US time standard on Riefler pendulum clocks, accurate to about 10 milliseconds per day. In 1929 it switched to the Shortt-Synchronome free pendulum clock before phasing in quartz standards in the 1930s.
https://en.wikipedia.org/wiki?curid=24989
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Light causes cumulative and irreversible damage to light-sensitive objects. The energy from light interacts with objects at the molecular level and can lead to both physical and chemical damage such as fading, darkening, yellowing, embrittlement, and stiffening. Ultraviolet radiation and Infrared radiation, in addition to visible light, can be emitted from light sources and can also be damaging to material culture. Cultural institutions are tasked with finding the balance between needing light for patrons and guests and exposure to the collection. Any amount of light can be damaging to a variety of objects and artworks and the effects are cumulative and irreversible. Conservation science has helped establish 50 Lux as the benchmark level of light intensity that allows the human eye to operate within the full range the visible light spectrum. While this is a baseline for many museums, adjustments are often needed for based on specific situations. Conservation science has informed the industry on the levels of light sensitivity of common materials used in material culture and the length of time permissible before deterioration is likely to occur. Control strategies must be considered on an item by item basis. Light, ultraviolet, and thermometers for infrared radiation are some of the tools used to detect when levels fall outside of an acceptable range.
https://en.wikipedia.org/wiki?curid=9962115
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The species was described from a type specimen, the holotype leaf, number SR 10-29-20 A&B, plus a pair paratype specimens, SR 92-05-05 and SR 97-03-15 A&B. The type series specimens are currently preserved in the paleobotanical collections of the Stonerose Interpretive Center in Republic, Washington. The specimens were studied by paleobotanists Soon Flynn and Kathleen Pigg of Arizona State University with Melanie DeVore of Georgia College and State University. They published their 2019 type description for "R. republicensis" in the "International Journal of Plant Sciences". The etymology of the chosen specific name "republicensis" is a reference to Republic, Washington where the collecting site is located. In addition to "Rhus republicensis" Flynn "et al" also provided descriptions of the coeval species "Rhus boothillensis" and "Rhus garwellii" and gave a redescription of "Rhus malloryi" in the 2019 paper. They noted that the Klondike Mountain Formation preserves a number of "Rhus" specimens which appear to be hybrids of the named species.
https://en.wikipedia.org/wiki?curid=61305146
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The study of mathematics as a "demonstrative discipline" began in the 6th century BC with the Pythagoreans, who coined the term "mathematics" from the ancient Greek "μάθημα" ("mathema"), meaning "subject of instruction". Greek mathematics greatly refined the methods (especially through the introduction of deductive reasoning and mathematical rigor in proofs) and expanded the subject matter of mathematics. Although they made virtually no contributions to theoretical mathematics, the ancient Romans used applied mathematics in surveying, structural engineering, mechanical engineering, bookkeeping, creation of lunar and solar calendars, and even arts and crafts. Chinese mathematics made early contributions, including a place value system and the first use of negative numbers. The Hindu–Arabic numeral system and the rules for the use of its operations, in use throughout the world today evolved over the course of the first millennium AD in India and were transmitted to the Western world via Islamic mathematics through the work of Muḥammad ibn Mūsā al-Khwārizmī. Islamic mathematics, in turn, developed and expanded the mathematics known to these civilizations. Contemporaneous with but independent of these traditions were the mathematics developed by the Maya civilization of Mexico and Central America, where the concept of zero was given a standard symbol in Maya numerals.
https://en.wikipedia.org/wiki?curid=14220
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Pyruvate kinase type M2 or PKM2 is present in embryonic, adult stem cells. It is also expressed by many tumor cells. The alterations to metabolism by PKM2 increases ATP resources, stimulates macromolecular biosynthesis and redox control. Pyruvate kinase catalyses the ATP-generating step of glycolysis in which phosphoenolpyruvate (PEP) is converted to pyruvate. This is a rate-limiting step. It decreases the glycolysis activity and allows carbohydrate metabolites to enter other pathways, like hexosamine pathway, Uridine diphosphate glucose–glucose synthesis, glycerol synthesis and Pentose phosphate pathway or PPP. It helps in generating macromolecule precursors, that are necessary to support cell proliferation, and reducing equivalents such as NADPH. It has been observed in some studies that MYC promotes expression of PKM2 over PKM1 by modulating exon splicing.
https://en.wikipedia.org/wiki?curid=4683065
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Wu quickly became a full professor in 1958, and later on was named the first Michael I. Pupin Professor of Physics in 1973. Some of her impish students called her the Dragon Lady, after the character of that name in the comic strip "Terry and the Pirates" due to Wu's strictness and high standards of excellence. Regardless of this, Wu actually treated her students like her children and often ate lunch with them as well as got to know their entourages. She would do this while working from 8 am to 7 or 8 in the evening, with her pay still very low until it was drastically increased after Robert Serber was installed as the new chairman. Her discoveries proved to be important in physics and her work even crossed over to biology and medicine, where her contributions became extremely influential to certain studies on the molecular changes in red blood cells that caused sickle-cell disease or anemia.
https://en.wikipedia.org/wiki?curid=252131
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In January 2016, the SM-6 demonstrated both maximum down range and maximum cross range intercepts in over-the-horizon, engage-on-remote missions supported by CEC, breaking the previous maximum engagement record it set in June 2014. Five targets were shot down in the test, proving the missile's capability to conduct multiple target scenarios. The SM-6 also sunk the decommissioned in an 18 January 2016 demonstration, displaying its anti-ship capabilities. On 30 September 2016, Raytheon announced the SM-6 had again achieved the longest surface-to-air intercept in naval history, breaking its previous long-range intercept record made in January 2016. On 14 December 2016, the Missile Defense Agency successfully launched two SM-6 Dual I missiles at a "complex, medium-range ballistic missile target", proving that its explosive—rather than hit-to-kill—warhead was capable of defeating medium range ballistic missile threats; this ability may enable it to counter Chinese DF-21D and DF-26B anti-ship ballistic missile threats.
https://en.wikipedia.org/wiki?curid=17238099
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Malthusianism has attracted criticism from diverse schools of thought, including Georgists, Marxists and socialists, libertarians and free market enthusiasts, feminists and human rights advocates, characterising it as excessively pessimistic, misanthropic or inhuman. Many critics believe Malthusianism has been discredited since the publication of "Principle of Population", often citing advances in agricultural techniques and modern reductions in human fertility. Some modern proponents believe that the basic concept of population growth eventually outstripping resources is still fundamentally valid, and that positive checks are still likely to occur in humanity's future if no action is taken to intentionally curb population growth. In spite of the variety of criticisms against it, the Malthusian argument remains a major discourse based on which national and international environmental regulations are promoted.
https://en.wikipedia.org/wiki?curid=1454728
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Flight Day 2 saw the crew of "Discovery" begin their preparations to dock with the International Space Station (ISS). The day started with a firing of the Orbital Maneuvering System (OMS) engine, called the NC2 burn, to help "Discovery" catch up to the ISS. Commander Steve Lindsey, Pilot Eric Boe and Mission Specialist Al Drew began the day performing an inspection of the Re-enforced Carbon-Carbon (RCC) panels with the Orbital Boom Sensor System (OBSS). Lindsey and Boe started the inspection on the starboard wing and nose cap, and continued on with the port wing; the whole survey took about six hours to complete. Drew joined up with Michael Barratt and Steve Bowen to checkout and get their two Extravehicular Mobility Units (EMUs) ready for the two spacewalks that would be conducted during the mission. Later in the day, the crew checked out the rendezvous tools to ensure they were operational. At the end of the day, another OMS engine firing, known as the NC3 burn, took place.
https://en.wikipedia.org/wiki?curid=5829815
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NetBSD was originally derived from the 4.3BSD-Reno release of the Berkeley Software Distribution from the Computer Systems Research Group of the University of California, Berkeley, via their Net/2 source code release and the 386BSD project. The NetBSD project began as a result of frustration within the 386BSD developer community with the pace and direction of the operating system's development. The four founders of the NetBSD project, Chris Demetriou, Theo de Raadt, Adam Glass, and Charles Hannum, felt that a more open development model would benefit the project: one centered on portable, clean, correct code. They aimed to produce a unified, multi-platform, production-quality, BSD-based operating system. The name "NetBSD" was chosen based on the importance and growth of networks such as the Internet at that time, and the distributed, collaborative nature of its development.
https://en.wikipedia.org/wiki?curid=28901365
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On November 27, 2017, the university announced that its athletic programs have begun a 6-year transition process from NCAA Division II to Division I, where it will be a member of the Big West Conference. As of 2017 most of UC San Diego's 23 intercollegiate varsity athletic teams still participate in Division II, 12-member California Collegiate Athletic Association, and some compete independently. The water polo, fencing, and men's volleyball teams compete as part of Division I conferences. Before joining Division II in 2000, the school participated at the Division III level. The teams compete at the university's RIMAC facility, Triton Ballpark, and RIMAC Arena. University of California, San Diego was ranked #1 among all NCAA D2 schools in the country and #40 overall (for all divisions), according to the Next College Student Athlete's 2018 NCSA Power Rankings. The NCSA Power Rankings recognize the best colleges and universities in the U.S. for student-athletes. UC San Diego athletics also ranked #1 in men's and women's soccer, women's volleyball, men's and women's basketball, men's and women's swimming, men's and women's track and field, men's and women's tennis, men's golf, women's rowing, softball, and baseball, among all NCAA D2 schools. Additionally, UC San Diego ranked #1 in Men's Water Polo and Men's Volleyball among NCAA D1 schools.
https://en.wikipedia.org/wiki?curid=31927
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Overhead due to linear dependencies: Since the coding coefficients are chosen randomly in RLNC, there is a chance that some transmitted coded packets are not beneficial to the destination because they are formed using a linearly dependent combination of packets. However, this overhead is negligible in most applications. The linear dependencies depend on the Galois fields' size and are practically independent of the generation size used. We can illustrate this with the following example. Let us assume we are using a Galois field of formula_48 elements and a generation size of formula_26 packets. If the destination has not received any coded packet, we say it has formula_26 degrees of freedom, and then almost any coded packet will be useful and innovative. In fact, only the zero-packet (only zeroes in the coding coefficients) will be non-innovative. The probability of generating the zero-packet is equal to the probability of each of the formula_26 coding coefficient to be equal to the zero-element of the Galois field. I.e., the probability of a non-innovative packet is of formula_52. With each successive innovative transmission, it can be shown that the exponent of the probability of a non innovative packet is reduced by one. When the destination has received formula_53 innovative packets (i.e., it needs only one more packet to fully decode the data). Then the probability of a non innovative packet is of formula_54. We can use this knowledge to calculate the expected number of linearly dependent packets per generation. In the worst-case scenario, when the Galois field used contains only two elements (formula_55), the expected number of linearly dependent packets per generation is of 1.6 extra packets. If our generation size if of 32 or 64 packets, this represents an overhead of 5% or 2.5%, respectively. If we use the binary-8 field (formula_56), then the expected number of linearly dependent packets per generation is practically zero. Since it is the last packets the major contributor to the overhead due to linear dependencies, there are RLNC-based protocols such as tunable sparse network coding that exploit this knowledge. These protocols introduce sparsity (zero-elements) in the coding coefficients at the beginning of the transmission to reduce the decoding complexity, and reduce the sparsity at the end of the transmission to reduce the overhead due to linear dependencies.
https://en.wikipedia.org/wiki?curid=3084295
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NIT Trichy is funded by the Ministry of Education (MoE), Government of India; and focuses exclusively on engineering, management, science, technology and architecture. The institute offers 10 bachelor's, 40 master's and 17 doctoral programmes through its 17 academic departments and awards more than 1900 degrees annually. The "National Institutional Ranking Framework" "(NIRF)" ranked the institute first among the NITs for seven years in a row from 2016 to 2022. "NIRF" also ranked the institute 5 for architecture, 8 for engineering, 3 for management and 23 overall among the academic institutions in India in 2022. NIT Trichy was titled the "Best Industry-linked Centrally Funded Technical Institution in India" by the Confederation of Indian Industry in 2015, and "University of the Year" by the Federation of Indian Chambers of Commerce and Industry in 2017.
https://en.wikipedia.org/wiki?curid=62648373
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The MMOAS degree requires study in many academic disciplines related to war, peace, and the employment of military forces. They include established academic fields of study such as sociology, history, engineering, psychology, politics, geography, science, ethics, economics, anthropology, and others. It may also include other professional fields of practice such as medicine and the law insofar as they interact with the military or are applied to military matters. It provides intellectual and theoretical depth to the military profession and its practitioners. Thus, a large proportion of research in the field of military art and science is done to address practical problems faced by practitioners. Purely academic research, however, is also an integral part of the field and is essential to ensure its continued intellectual vitality. The results of scholarship and research in the field may be of interest and may be helpful to political leaders and policymakers, military officers, as well as to scholars and the interested public.
https://en.wikipedia.org/wiki?curid=6530173
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As extreme as MAV specifications were, a team under Ilan Kroo at Stanford University worked on an even more extreme design in the form of a centimeter-wide four-rotor mesicopter using microcircuit fabrication techniques. The work was funded by NASA. Design of such a small aircraft was constrained by the fact that at such scales, the air becomes a highly viscous medium, or in aerodynamic terms a mesicopter had a low Reynolds number. Basic aerodynamics of the mesicopter were defined by a cycle of computer simulation, followed by tests of model components. The research led to mesicopter rotor designs where the rotor looked much more like the blades of an ordinary room fan than the rotor of a conventional helicopter. Propeller designs did not achieve desired efficiency and the Mesicopter was never able to lift the weight of its own energy source.
https://en.wikipedia.org/wiki?curid=3525527
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Block E is located to the south of the courtyard between Blocks B and G/H. Now four storeys, it has grown out of the former Chemistry and Geology building and is unified with the other buildings in the group in general elevational composition, detailing and materials. It is a plain building in light red facebrick with contrasting dark red facebrick to the relieved quoins, flat window arches and banding marking the interior floor levels. The only decoration is the Art Nouveau metal lettering "Chemistry" above the arched entrance porch to the east. The 1937 infill to the northeast continues the original elevational treatments and is well matched to the original while the 1960s addition to the southwest corner in light brick with no texturing or banding and smaller vertical fenestration is less sympathetic. The solid balustraded, setback upper-storey (1990) contrasts with the rest of the building and disturbs the building's cohesion with the group. A barrel-shaped, corrugated metal hood has been added over the steps to the east entrance porch.
https://en.wikipedia.org/wiki?curid=3049824
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Much of opposition to the proposed Constitution within several states arose, not because the machinery of the new frame of government was considered unworkable or because strengthening the union between the 13 states viewed as undesirable. The debates in the state ratifying conventions centered around the absence of anything equivalent to the bill of rights found in several state constitutions. George Mason, a delegate to the 1787 Constitutional Convention, and the author of the Virginia Declaration of Rights, refused to sign the document because he felt it did not specifically spell out or protect individual rights sufficiently. He also opposed the constitution when it was brought before the state for ratification. He acquiesced and the convention voted narrowly to give its assent only after it was decided that a list of twenty proposed amendments be sent along with the state's resolution of ratification. Delegates to Massachusetts' convention had many of the same concerns, and along with its notification of approval made a request for nine alterations, the first among them being "that it be explicitly declared that all powers not specifically delegated to Congress by the Constitution are reserved to the states to be exercised by them." New York, not to be outdone, appended a list of thirty-two requested amendments plus a lengthy statement of "impressions" and "explanations" about the new Constitution to their affirmative vote.
https://en.wikipedia.org/wiki?curid=497752
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Otto engines are about 30% efficient; in other words, 30% of the energy generated by combustion is converted into useful rotational energy at the output shaft of the engine, while the remainder being lost due to waste heat, friction and engine accessories. There are a number of ways to recover some of the energy lost to waste heat. The use of a turbocharger in diesel engines is very effective by boosting incoming air pressure and in effect, provides the same increase in performance as having more displacement. The Mack Truck company, decades ago, developed a turbine system that converted waste heat into kinetic energy that it fed back into the engine's transmission. In 2005, BMW announced the development of the turbosteamer, a two-stage heat-recovery system similar to the Mack system that recovers 80% of the energy in the exhaust gas and raises the efficiency of an Otto engine by 15%. By contrast, a six-stroke engine may reduce fuel consumption by as much as 40%.
https://en.wikipedia.org/wiki?curid=170045
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Shallow trench isolation (STI), a process used to fabricate semiconductor devices, is a technique used to enhance the isolation between devices and active areas. Moreover, STI has a higher degree of planarity making it essential in photolithographic applications, depth of focus budget by decreasing minimum line width. To planarize shallow trenches, a common method should be used such as the combination of resist etching-back (REB) and chemical mechanical polishing (CMP). This process comes in a sequence pattern as follows. First, the isolation trench pattern is transferred to the silicon wafer. Oxide is deposited on the wafer in the shape of trenches. A photo mask, composed of silicon nitride, is patterned on the top of this sacrificial oxide. A second layer is added to the wafer to create a planar surface. After that, the silicon is thermally oxidized, so the oxide grows in regions where there is no SiN and the growth is between 0.5 and 1.0 μm thick. Since the oxidizing species such as water or oxygen are unable to diffuse through the mask, the nitride prevents the oxidation. Next, the etching process is used to etch the wafer and leave a small amount of oxide in the active areas. In the end, CMP is used to polish the SiO overburden with an oxide on the active area.
https://en.wikipedia.org/wiki?curid=1253327
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The car was liveried in white, with blue stripes running down the sides of the cockpit and on top of each of its sidepods. Several sponsor stickers were on a number of areas of the car. The vehicle's race number was placed in a red square on the middle of the top section of its front left fender and the far-right of both fenders. The livery incorporated the colour scheme of Toyota's hybrid production cars and returned to the livery used by the Japanese manufacturer between 1985 and 1993. Toyota publicly announced its return to sports car racing in October 2011. Three months later the first car undertook a three-day, private test session at Circuit Paul Ricard. Toyota planned to test their TS030s for during the 2012 pre-season period. The company entered into a partnership with the French-based Oreca racing team for the provision of operational support.
https://en.wikipedia.org/wiki?curid=34484574
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However, there are several major problems with the methane hydrate dissociation hypothesis. The most parsimonious interpretation for surface-water forams to show the excursion before their benthic counterparts (as in the Thomas et al. paper) is that the perturbation occurred from the top down, and not the bottom up. If the anomalous (in whatever form: CH or ) entered the atmospheric carbon reservoir first, and then diffused into the surface ocean waters, which mix with the deeper ocean waters over much longer time-scales, we would expect to observe the planktonics shifting toward lighter values before the benthics. Moreover, careful examination of the Thomas et al. data set shows that there is not a single intermediate planktonic foram value, implying that the perturbation and attendant anomaly happened over the lifespan of a single foram – much too fast for the nominal 10,000-year release needed for the methane hypothesis to work.
https://en.wikipedia.org/wiki?curid=387369
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There are challenges surrounding the availability of medical equipment from a global health perspective, with low-resource countries unable to obtain or afford essential and life-saving equipment. In these settings, well-intentioned equipment donation from high- to low-resource settings is a frequently used strategy to address this through individuals, organisations, manufacturers and charities. However, issues with maintenance, availability of biomedical equipment technicians (BMET), supply chains, user education and the appropriateness of donations means these frequently fail to deliver the intended benefits. The WHO estimates that 95% of medical equipment in low- and middle-income countries (LMICs) is imported and 80% of it is funded by international donors or foreign governments. While up to 70% of medical equipment in sub-Saharan Africa is donated, only 10%–30% of donated equipment becomes operational. A review of current practice and guidelines for the donation of medical equipment for surgical and anaesthesia care in LMICs has demonstrated a high level of complexity within the donation process and numerous shortcomings. Greater collaboration and planning between donors and recipients is required together with evaluation of donation programs and concerted advocacy to educate donors and recipients on existing equipment donation guidelines and policies
https://en.wikipedia.org/wiki?curid=1363291
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Missions in the programme are selected through competitions in which members of the European scientific community submit proposals to ESA. During each competition, the agency outlines one of four mission categories for which proposals need to meet the criteria of. These are the "L"-class large missions, the "M"-class medium missions, the "S"-class small missions, and the "F"-class fast missions, each with differing budget caps and implementation timelines. The proposals are then reviewed by the AWG, SSEWG, engineers at ESA, and any relevant ad hoc working groups, as part of a feasibility study known as "Phase 0". Missions which require new technologies to be developed are reviewed during these studies at the Concurrent Design Facility at the European Space Research and Technology Centre. After the study, up to three proposals are selected as finalists in "Phase A", in which a preliminary design for each candidate mission is formulated. The SPC then makes a final decision on which proposal proceeds to phases "B" through "F", which include the development, construction, launch, and disposal of the spacecraft used in the mission. During Phase A, each candidate mission is assigned two competing contractors to build their spacecraft, and the contractor for the winning mission is chosen during Phase B.
https://en.wikipedia.org/wiki?curid=60457571
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"Super Mario Bros." has been used by several researchers to simulate PCG level creation. Various attempts having used different methods. A version in 2014 used n-grams to generate levels similar to the ones it trained on, which was later improved by making use of MCTS to guide generation. These generations were often not optimal when taking gameplay metrics such as player movement into account, a separate research project in 2017 tried to resolve this problem by generating levels based on player movement using Markov Chains. These projects were not subjected to human testing and may not meet human playability standards.
https://en.wikipedia.org/wiki?curid=60951296
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Female embryos were selectively transferred in five couples at risk of X-linked disease, resulting in two twins and one singleton pregnancy. Because the Y chromosome region Kontogianni was amplifying contained many repeats, it was more efficient than trying to amplify a unique region. A band on the PCR gel indicated that the embryo was male and the absence of a band indicated that the embryo was female. However, amplification failure or an anucleate blastomere also resulted in absence of a band on the PCR gel. To reduce the risk of misdiagnosis, Kontogianni went on to co-amplify sequences on the X and Y (Kontogianni et al., 1991). At that time nothing was known about allele dropout, cumulus cell contamination, or amplification failure from single cells. During the 1980s, human IVF embryos were exclusively transferred on day two of development as the culture medium used was incapable of reliably growing embryos past this stage. Since the biopsy was to be performed on day three, the first diagnoses were all performed in one day, with transfer of the embryos late on day three. A comparison of day two and day three transfers indicated that this would not adversely affect pregnancy rates. The worry of embryos arresting was so high that some transfers took place in the early hours of day four so that the embryos were removed from culture as soon as possible. There were many evenings at the Hammersmith when a transfer was performed at 1 a.m. on day four and researchers returned to the laboratory at 7 a.m. to start the next case. Winston helped deliver most of the first PGD babies.
https://en.wikipedia.org/wiki?curid=562180
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In 1898 Anstey College hosted a meeting that would lead to the creation, the following year, of the Ling Association (later renamed the Physical Education Association of the United Kingdom), and in 1907 the college moved to new premises at Yew Tree House, Chester Road, Erdington, Birmingham, which would remain its home for nearly 75 years. Rhoda Anstey stepped down as principal in 1927, after having partially retired in 1920, though she remained a co-director until 1930, in which year the college gained the approval of the University of London to grant accredited diplomas. During the 1930s and 1940s Anstey College students represented England at many international events and exhibitions, and in 1947 the college changed its name to the Anstey College of Physical Education. In 1949 it became a founder member of the International Association of Physical Education and Sport for Girls and Women.
https://en.wikipedia.org/wiki?curid=41016634
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The gamma-emitting isotopes iodine-123 (half-life 13 hours), and (less commonly) the longer-lived and less energetic iodine-125 (half-life 59 days) are used as nuclear imaging tracers to evaluate the anatomic and physiologic function of the thyroid. Abnormal results may be caused by disorders such as Graves' disease or Hashimoto's thyroiditis. Both isotopes decay by electron capture (EC) to the corresponding tellurium nuclides, but in neither case are these the metastable nuclides Te and Te (which are of higher energy, and are not produced from radioiodine). Instead, the excited tellurium nuclides decay immediately (half-life too short to detect). Following EC, the excited Te from I emits a high-speed 127 keV internal conversion electron (not a beta ray) about 13% of the time, but this does little cellular damage due to the nuclide's short half-life and the relatively small fraction of such events. In the remainder of cases, a 159 keV gamma ray is emitted, which is well-suited for gamma imaging.
https://en.wikipedia.org/wiki?curid=2526953
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New allergies could be introduced inadvertently, according to scientists, community groups, and members of the public concerned about the genetic variation of foods. An example involves the methionine rich soybean production. Methionine is an amino acid obtained by synthesizing substances derived from Brazil nuts, which could be an allergen. A gene from the Brazil nut was inserted into soybeans during laboratory trials. Because it was discovered that those who were allergic to Brazil nuts could also be allergic to genetically modified soybeans, the experiment was stopped. In vitro assays such as RAST or serum from people allergic to the original crop could be applied to testify the allergenicity of GM goods with known source of the gene. This was established in GM soybeans that expressed Brazil nut 2S proteins and GM potatoes that expressed cod protein genes. The expression and synthesis of new proteins that were previously unavailable in parental cells were achieved by gene transfer from the cells of one organism to the nuclei of another organism. The potential risks of allergy that may develop with the intake of transgenic food come from the amino acid sequence in protein formation. However, there have been no reports of allergic reactions to currently approved GM foods for human consumption, and experiments showed no measurable difference in allergenicity between GM and non-GM soybeans.
https://en.wikipedia.org/wiki?curid=216102
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Seismic interferometry applications are currently limited by a number of factors. Real world media and noise represent limitations for current theoretical development. For example, for interferometry to work noise sources must be uncorrelated and completely surround the region of interest. In addition, attenuation and geometrical spreading are largely neglected and need to be incorporated into more robust models. Other challenges are inherent to seismic interferometry. For example, the source term only drops out in the case of the crosscorrelation of a direct wave at a location A with a ghost reflection at a location B. The correlation of other waveforms can introduce multiples to the resulting interferogram. Velocity analysis and filtering can reduce but not eliminate the occurrence of multiples in a given dataset.
https://en.wikipedia.org/wiki?curid=27341944
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Additional research interests include investigations of terrestrial mass extinction horizons (including the late Eocene, K-Pg, Tr-J, and P-Tr strata), of meteorites and lunar rocks, Antarctic meteorite field studies, snowball earth, and several other geochemistry-related issues. He participated in or led numerous field expeditions, including Antarctica in 1986/7 and desert regions in Namibia, South Africa, Egypt, Libya, Mauritania, and Mongolia, and to numerous impact craters around the world. He participated in several documentary movies on impact related topics. From 1998 to 2003 he was chair and coordinator of the European Science Foundation "Impact" program. He is also on the science team of the Midas experiment on board the Rosetta comet probe.
https://en.wikipedia.org/wiki?curid=33363763
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Andrew Millar was raised in Luxembourg. He later attended Cambridge University where he received a Bachelor of Arts in 1988, studying genetics and winning University Prizes for botany in 1987 and genetics in 1988. After graduation, he began doctoral study in the United States at The Rockefeller University under the mentorship of Nam-Hai Chua, FRS, and graduated in 1994 with a PhD in plant molecular genetics. He then completed a postdoctoral fellowship at the National Science Foundation (NSF) Center for Biological Timing at the University of Virginia under the guidance of Steve A. Kay and Gene D. Block in 1995. In 1996, he joined the faculty of the University of Warwick, where he began to work on synthetic and systems biology in conjunction with plant chronobiology. He remained at Warwick until 2005, when he joined the faculty at The University of Edinburgh. Millar helped found SynthSys, a centre for synthetic and systems biology research partnered with the University of Edinburgh, in 2007.
https://en.wikipedia.org/wiki?curid=53763747
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For the Individual Carbine competition, Colt submitted their "Enhanced M4" design, also known as the Colt Advanced Piston Carbine (APC). The weapon has a suppression-ready fluted barrel, which is lighter and cools better than previous M4 barrels. It is claimed to have "markedly better" accuracy. To improve reliability, Colt used an articulating link piston (ALP), which "reduces the inherent stress in the piston stroke by allowing for deflection and thermal expansion". In traditional gas piston operating systems, the force of the piston striking the bolt carrier can push the bolt carrier downwards and into the wall of the buffer tube, leading to accelerated wear and even chipped metal. This is known as carrier tilt. The ALP allows the operating rod to wiggle to correct for the downward pressure on the bolt and transfers the force straight backwards in line with the bore and buffer assembly, eliminating the carrier tilt. This relieves stress on parts and helps to increase accuracy. The Individual Carbine competition was canceled before a winning weapon was chosen.
https://en.wikipedia.org/wiki?curid=321957
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Instead of a model-dependent treatment in terms of constituent quarks, hadrons are represented by their interpolating quark currents taken at large virtualities. The correlation function of these currents is introduced and treated in the framework of the operator product expansion (OPE), where the short and long-distance quark-gluon interactions are separated. The former are calculated using QCD perturbation theory, whereas the latter are parametrized in terms of universal vacuum condensates or light-cone distribution amplitudes. The result of the QCD calculation is then matched, via dispersion relation, to a sum over hadronic states. The sum rule obtained in this way allows to calculate observable characteristics of the hadronic ground state. Inversely, the parameters of QCD such as quark masses and vacuum condensate densities can be extracted from sum rules which have experimentally known hadronic parts. The interactions of quark-gluon currents with QCD vacuum fields critically depend on the quantum numbers (spin, parity, flavor content) of these currents.
https://en.wikipedia.org/wiki?curid=18327991
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A typical protocol to isolate a pure chemical agent from natural origin is bioassay-guided fractionation, meaning step-by-step separation of extracted components based on differences in their physicochemical properties, and assessing the biological activity, followed by next round of separation and assaying. Typically, such work is initiated after a given crude drug formulation (typically prepared by solvent extraction of the natural material) is deemed "active" in a particular "in vitro" assay. If the end-goal of the work at hand is to identify which one(s) of the scores or hundreds of compounds are responsible for the observed "in vitro" activity, the path to that end is fairly straightforward:
https://en.wikipedia.org/wiki?curid=592949
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Financial concerns were raised in 2009 over the cost of the new leisure complex, and because of a change in the source of student funding from the Learning and Skills Council to Local Education Authorities. The college was facing a shortfall of at least £500,000 in 2009 and its auditors expressed doubt about RNC's ability to continue as a going concern. In response Ian Pickford said that much of thePoint4's costs had been paid for through donations and that the shortfall issue was being addressed through cutbacks, including some redundancies. Of the auditors' concerns he said; "I think post the banking crisis a lot of auditors are incredibly nervous about making bland statements in terms of the future of organisations and therefore they frequently now put those sort of caveats in to protect their position going forward."
https://en.wikipedia.org/wiki?curid=5556351
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Psychologists who work with animals assume that the things they learn can be applied to the human brain. Memory is a complex system that relies on interactions between many distinct parts of the brain. In order to fully understand memory, researchers must cumulate evidence from human, animal, and developmental research in order to make broad theories about how memory works. Intraspecies comparisons are key. Rats for example display extremely complex behaviours and most of the structures in their brain parallel those in humans. Due to their relatively simple organization, slugs can be useful for studying how neurons interconnect to produce observable behaviour. Fruit flies are useful for studying gene-behaviour interactions because many generations with genetic alterations can be quickly bred in the laboratory.
https://en.wikipedia.org/wiki?curid=26685721
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AI algorithms can also be used to analyze large amounts of data through electronic health records for disease prevention and diagnosis. Medical institutions such as The Mayo Clinic, Memorial Sloan Kettering Cancer Center, and the British National Health Service, have developed AI algorithms for their departments. Large technology companies such as IBM and Google, have also developed AI algorithms for healthcare. Additionally, hospitals are looking to AI software to support operational initiatives that increase cost saving, improve patient satisfaction, and satisfy their staffing and workforce needs. Currently, the United States government is investing billions of dollars to progress the development of AI in healthcare. Companies are developing technologies that help healthcare managers improve business operations through increasing utilization, decreasing patient boarding, reducing length of stay and optimizing staffing levels.
https://en.wikipedia.org/wiki?curid=52588198
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Some of the largest communities of zooplankton exist in high latitude systems like the eastern Bering Sea; pockets of dense zooplankton abundance also exist in the California Current and the Gulf of Mexico. Zooplankton are, in turn, common prey items for planktivores; they respond to environmental change very rapidly due to their relatively short life spans, and so scientists can track their dynamics to understand what might be occurring in the larger marine food web and environment. The relative ratios of certain zooplankton in the larger zooplankton community can also indicate an environmental change (e.g., eutrophication) that may be significant. For instance, an increase in rotifer abundance in the Great Lakes has been correlated with abnormally high levels of nutrients (eutrophication).
https://en.wikipedia.org/wiki?curid=36726184
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Returnal is a third-person shooter roguelike video game developed by Housemarque and published by Sony Interactive Entertainment. It was released for the PlayStation 5 on April 30, 2021. The game follows Selene Vassos, an astronaut who lands on the planet Atropos in search of the mysterious "White Shadow" signal and finds herself trapped in a time loop. "Returnal" received generally favorable reviews for its visuals, combat, audio design and technical achievements, though its difficulty and roguelike design were met with mixed opinions. It won several end-year accolades, including Best Game at the 18th British Academy Games Awards. The game is set to release on Windows in early 2023.
https://en.wikipedia.org/wiki?curid=64255994
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Modern geology, its sub-disciplines and other scientific disciplines use the scientific method to analyze the geology of the earth. The key tenets of flood geology are refuted by scientific analysis and do not have any standing in the scientific community. Modern geology relies on a number of established principles, one of the most important of which is Charles Lyell's principle of uniformitarianism. In relation to geological forces it states that the shaping of the Earth has occurred by means of mostly slow-acting forces that can be seen in operation today. By applying these principles, geologists have determined that the Earth is approximately 4.54 billion years old. They study the lithosphere of the Earth to gain information on the history of the planet. Geologists divide Earth's history into eons, eras, periods, epochs, and faunal stages characterized by well-defined breaks in the fossil record (see Geologic time scale). In general, there is a lack of any evidence for any of the above effects proposed by flood geologists and their claims of fossil layering are not taken seriously by scientists.
https://en.wikipedia.org/wiki?curid=543667
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MHC Class I molecules such as HLA-A are part of a process that presents short polypeptides to the immune system. These polypeptides are typically 7-11 amino acids in length and originate from proteins being expressed by the cell. There are two classes of polypeptide that can be presented by an HLA protein: those that are supposed to be expressed by the cell (self) and those of foreign derivation (non-self). Under normal conditions cytotoxic T cells, which normally patrol the body in the blood, "read" the peptide presented by the complex. T cells, if functioning properly, only bind to non-self peptides. If binding occurs, a series of events is initiated culminating in cell death via apoptosis. In this manner, the human body eliminates any cells infected by a virus or expressing proteins they shouldn't be (e.g. cancerous cells).
https://en.wikipedia.org/wiki?curid=7718899
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The California Academy of Sciences (CAS) in San Francisco is one of the four largest institutions of its kind in the United States and is the oldest on the West Coast. Researchers at the Academy study the origins, evolution and diversity of species, their adaptations, systematics and phylogenetics. The Department of Anthropology joins departments of Ichthyology, Herpetology, Ornithology and Mammalogy, Aquatic Biology, Invertebrate Zoology and Geology, Entomology and Botany, as well as centers for Applied Biodiversity Informatics and Comparative Genomics, to study the biodiversity and evolution of living things through fundamental laboratory and field research. This collaborative environment, in which original research and public outreach are given primacy, is an ideal setting for Zeresenay's interests.
https://en.wikipedia.org/wiki?curid=7098772
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According to the Carnegie Mellon School an organization's ability to process information is at the core of organizational and managerial competency, and an organization's strategies must be designed to improve information processing capability and as information systems that provide that capability became formalised and automated, competencies were severely tested at many levels. It was recognised that organisations needed to be able to learn and adapt in ways that were never so evident before and academics began to organise and publish definitive works concerning the strategic management of information, and information systems. Concurrently, the ideas of business process management and knowledge management although much of the optimistic early thinking about business process redesign has since been discredited in the information management literature. In the strategic studies field, it is considered of the highest priority the understanding of the information environment, conceived as the aggregate of individuals, organizations, and systems that collect, process, disseminate, or act on information. This environment consists of three interrelated dimensions which continuously interact with individuals, organizations, and systems. These dimensions are the physical, informational, and cognitive.
https://en.wikipedia.org/wiki?curid=464877
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Bacillus atrophaeus is a species of black-pigmented bacteria. Its type strain is NRRL NRS-213. "B. atrophaeus" strains have been used extensively in biomedicine as indicator strains for heat- and chemical-based decontamination regimens. Most of the strains in use are derivatives of a lineage of "B. atrophaeus" that originated at Camp Detrick in the 1950s, where many modern biocontainment procedures were developed. "B. atrophaeus" has historically been known by several other names, including "B. globigii" (the origin of its military moniker "BG") and "B. subtilis" var. "niger". Modern phylogenetic analyses using multiple genetic methods have placed "B. atrophaeus" close to "B. subtilis". Its original and still most prominent use is as a surrogate organism for pathogenic "B. anthracis", beginning in the U.S. bio-weapons program, as its pigmentation readily facilitated discrimination from non-pigmented background organisms in environmental samples.
https://en.wikipedia.org/wiki?curid=37578595
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Concerns about chemicals ingested by children when chewing plastic toys prompted the European Commission to order a temporary ban on phthalates in 1999, the decision of which is based on an opinion by the Commission's Scientific Committee on Toxicity, Ecotoxicity and the Environment (CSTEE). A proposal to make the ban permanent was tabled. Until 2004, EU banned the use of DEHP along with several other phthalates (DBP, BBP, DINP, DIDP and DNOP) in toys for young children. In 2005, the Council and the Parliament compromised to propose a ban on three types of phthalates (DINP, DIDP, and DNOP) "in toys and childcare articles which can be placed in the mouth by children". Therefore, more products than initially planned will thus be affected by the directive. In 2008, six substances were considered to be of very high concern (SVHCs) and added to the Candidate List including musk xylene, MDA, HBCDD, DEHP, BBP, and DBP. In 2011, those six substances have been listed for Authorization in Annex XIV of REACH by Regulation (EU) No 143/2011. According to the regulation, phthalates including DEHP, BBP and DBP will be banned from February 2015.
https://en.wikipedia.org/wiki?curid=3003614
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In the United States, the Transportation Security Administration (TSA) claimed to have taken steps to address privacy objections. TSA claimed that the images captured by the machines were not stored. On the other hand, the U.S. Marshals Service admitted that it had saved thousands of images captured from a Florida checkpoint. The officer sitting at the machine does not see the image; rather that screen shows only whether the viewing officer has confirmed that the passenger has cleared. Conversely, the officer who views the image does not see the person being scanned by the device. In some locations, updated software has removed the necessity of a separate officer in a remote location. These units now generate a generic image of a person, with specific areas of suspicion highlighted by boxes. If no suspicious items are detected by the machine, a green screen instead appears indicating the passenger is cleared.
https://en.wikipedia.org/wiki?curid=16959357
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Using perovskite crystals as an example, Bersuker showed (first in 1964, published in 1966) that the PJTE produces a spontaneous symmetry breaking resulting under certain conditions in local dipolar instability. It exists in all the crystal phases, and the spontaneous polarization results from the order-disorder interaction between these PJTE-induced local dipolar distortions. Performed in the local octahedral TiO center in the BaTiO crystal (taken as an example), where vibronic coupling mixes ground "A" and close in energy exited "T" states of opposite parity (but same multiplicity), detailed analysis with calculations proved the PJTE to produce the dipolar distortion. Thus, it shows that Bersuker's PJTE theory of ferroelectricity agrees with the available empirical data and predicts new properties, confirmed experimentally.
https://en.wikipedia.org/wiki?curid=68664805
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Another possible explanation to the prevalence of substance use is that it contributes to mating success by altering brain functions that lower inhibitions. Generally, people seem to believe substance use will enhance their social behaviors in ways conducive to mating success. Research has shown that many drug types inhibit prefrontal cortex neural activity, the area of the brain responsible conducting long term gains and short term costs. Alcohol myopia theory suggest alcohol lowers inhibitions and amplifies the pre-drinking intention to have sex. Research has also shown that alcohol stimulates dopamine activity in the mesolimbic-dopamine system, which amplifies the salience of natural rewards (e.g. finding food and mates) in the present environment and boost associative learning.
https://en.wikipedia.org/wiki?curid=53918629
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In 1998, three international conferences: Visualization in Biomedical Computing (VBC), Computer Vision and Virtual Reality in Robotics and Medicine (CVRMed), and Medical Robotics and Computer Assisted Surgery (MRCAS) merged into a single conference entitled "The International Conference on Medical Image Computing and Computer Assisted Interventions" (abbreviated MICCAI) with its first edition in Boston. The MICCAI Society was founded in 2004 by several active members of this research community and former chairs of the MICCAI conference. In 2009, the society introduced the "MICCAI Fellow" award to recognize senior members who had made substantial contributions to the MICCAI community. 12 fellows were elected in 2009 and three additional fellows are elected each year. New MICCAI Fellows are announced each year at the Annual MICCAI Conference. Since 2012, the society is involved in several events each year outside of the annual conference through endorsements and/or sponsorships. These include a number of smaller international conferences, MICCAI-focused workshop sessions at related conferences, and educational programs such as "summer schools".
https://en.wikipedia.org/wiki?curid=63572622
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The gaseous diffusion plant was the most complicated of all from an engineering point of view. Uranium hexafluoride gas was pumped into a cascade, becoming richer in uranium-235 at each stage as it passed through a series of membranes. Procuring the nickel powder used by the Manhattan Project was not a problem, as it came from a British firm. Once again, a Royal Ordnance Factory was chosen as the site, in this case ROF Capenhurst at Capenhurst, near Chester, which had the advantage of being only from Risley. One decision was that instead of producing uranium hexafluoride using elemental fluorine, which was difficult and hazardous to transport, it was produced at Springfields from chlorine trifluoride. This process was untried and did not work properly, and when production commenced in February 1952, the hexafluoride plant did not perform adequately. It had to be redesigned at a cost of £250,000. The gaseous diffusion plant at Capenhurst, which cost £14 million, started production in 1953, but only produced low-enriched uranium, and did not produce highly enriched uranium until 1954. By 1957 it was capable of producing 125 kg of highly enriched uranium per annum. British designs at this time used large amounts of enriched uranium; 87 kg for Green Bamboo, 117 kg for Orange Herald. At the end of 1961, having produced between 3.8 and 4.9 tonnes of highly enriched uranium, it was switched over to low-enriched uranium production for civil nuclear power.
https://en.wikipedia.org/wiki?curid=52573493
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In the 16th century Vincenzo Galilei challenged the prevailing Pythagorean wisdom about the relationship between pitches and weights attached to strings. Vincenzo Galilei, the father of Galileo Galilei, engaged in an extended public exchange with his former teacher Zarlino. Zarlino supported the theory that if two weights in the ratio of 2 to 1 were attached to two strings, the pitches generated by the two strings would produce the octave. Vincenzo Galilei proclaimed that he had been a committed Pythagorean, until he "ascertained the truth by means of experiment, the teacher of all things." He devised an experiment which showed that the weights attached to the two strings needed to increase as the square of the string length. This public challenge to prevailing numerology in musical theory triggered an experimental and physical approach to acoustics in the 17th century. Acoustics emerged as a mathematical field of music theory and later an independent branch of physics. In the experimental investigation of sound phenomena, numbers had no symbolic meaning and were merely used to measure physical phenomena and relationships such as frequency and vibration of a string.
https://en.wikipedia.org/wiki?curid=291170
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Emotion appears able to aid the decision-making process. Decision-making often occurs in the face of uncertainty about whether one's choices will lead to benefit or harm (see also Risk). The somatic marker hypothesis is a neurobiological theory of how decisions are made in the face of uncertain outcomes. This theory holds that such decisions are aided by emotions, in the form of bodily states, that are elicited during the deliberation of future consequences and that mark different options for behavior as being advantageous or disadvantageous. This process involves an interplay between neural systems that elicit emotional/bodily states and neural systems that map these emotional/bodily states. A recent lesion mapping study of 152 patients with focal brain lesions conducted by Aron K. Barbey and colleagues provided evidence to help discover the neural mechanisms of emotional intelligence.
https://en.wikipedia.org/wiki?curid=265752
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"Millennials Rising" ascribes seven "core traits" to Millennials: special, sheltered, confident, team-oriented, conventional, pressured, and achieving. A 2009, "Chronicle of Higher Education" report commented Howe and Strauss based these core traits on a "hodgepodge of anecdotes, statistics, and pop-culture references" and on surveys of approximately 600 high-school seniors from Fairfax County, Virginia, an affluent county with median household income approximately twice the national average. The report described "Millennials Rising" as a "good-news revolution" making "sweeping predictions" and describing Millennials as "rule followers who were engaged, optimistic, and downright pleasant", commenting the "book gave educators and tens of millions of parents, a warm feeling, saying who wouldn't want to hear that their kids are special?"
https://en.wikipedia.org/wiki?curid=28937240
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A notable number of species have developed special glands that produce chemicals for deterring predators (see Defense and predation). The Ground beetle's (of Carabidae) defensive glands, located at the posterior, produce a variety of hydrocarbons, aldehydes, phenols, quinones, esters, and acids released from an opening at the end of the abdomen. While African carabid beetles (e.g., "Anthia" some of which used to comprise the genus "Thermophilum") employ the same chemicals as ants: formic acid. While Bombardier beetles have well developed, like other carabid beetles, pygidial glands that empty from the lateral edges of the intersegment membranes between the seventh and eighth abdominal segments. The gland is made of two containing chambers. The first holds hydroquinones and hydrogen peroxide, with the second holding just hydrogen peroxide plus catalases. These chemicals mix and result in an explosive ejection, forming temperatures of around 100 C, with the breakdown of hydroquinone to H + O + quinone, with the O propelling the excretion.
https://en.wikipedia.org/wiki?curid=24104729
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George E. Martin, PhD, served as the institution’s 23rd president. From Fall 1999–Summer 2021, Dr. Martin oversaw a period of expansion for St. Edward’s that included transforming the campus through the construction of many new buildings, doubling enrollment, growing the endowment, building global partnerships and founding the Holy Cross Institute to sustain the mission of the Brothers of the Congregation of Holy Cross. In February 2022, Dr. Montserrat ‘Montse’ Fuentes was inaugurated as the 24th president and first Hispanic president of St. Edward’s University. As part of her presidential inaugural address, Dr. Fuentes unveiled the university’s Strategic Plan 2027, a roadmap that articulates how St. Edward’s will continue its mission of serving as a destination university known for academic distinction, inclusive excellence and a commitment to social justice.
https://en.wikipedia.org/wiki?curid=332070
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"Dōjinshi", produced by small publishers outside of the mainstream commercial market, resemble in their publishing small-press independently published comic books in the United States. Comiket, the largest comic book convention in the world with around 500,000 visitors gathering over three days, is devoted to "dōjinshi". While they most often contain original stories, many are parodies of or include characters from popular manga and anime series. Some "dōjinshi" continue with a series' story or write an entirely new one using its characters, much like fan fiction. In 2007, "dōjinshi" sales amounted to 27.73 billion yen (US$245 million). In 2006 they represented about a tenth of manga books and magazines sales.
https://en.wikipedia.org/wiki?curid=18985
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Morris Kline was a protagonist in the curriculum reform in mathematics education that occurred in the second half of the twentieth century, a period including the programs of the new math. An article by Kline in 1956 in "The Mathematics Teacher" was titled "Mathematical texts and teachers: a tirade". Calling out teachers that blame students for their failures, he wrote "There is a student problem, but there are also three other factors which are responsible for the present state of mathematical learning, namely, the curricula, the texts, and the teachers." The tirade touched a nerve, and changes started to happen. But then Kline switched to being a critic of some of the changes. In 1958 he wrote "Ancients versus moderns: a new battle of the books". The article was accompanied with a rebuttal by Albert E. Meder Jr. of Rutgers University. He says, "I find objectionable: first, vague generalizations, entirely undocumented, concerning views held by 'modernists', and second, the inferences drawn from what has not been said by the 'modernists'."
https://en.wikipedia.org/wiki?curid=826363
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In 1971, researchers at Battelle Memorial Institute in Columbus, Ohio began investigating whether the laser shocking process could improve metal mechanical properties using a high energy pulsed laser. In 1972, the first documentation of the beneficial effects of laser shocking metals was published, reporting the strengthening of aluminum tensile specimens using a quartz overlay to confine the plasma. Subsequently, the first patent on laser shock peening was granted to Phillip Mallozzi and Barry Fairand in 1974. Research into the effects and possible applications of laser peening continued throughout the 1970s and early 1980s by Allan Clauer, Barry Fairand and coworkers, supported by funding from the National Science Foundation3, NASA, Army Research Office, U. S. Air Force, and internally by Battelle. This research explored the in-material effects in more depth and demonstrated the creation of deep compressive stresses and the accompanying increase in fatigue and fretting fatigue life achieved by laser peening.
https://en.wikipedia.org/wiki?curid=7465720
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The MITR-II design uses finned plate-type fuel arranged in a hexagonal pattern of rhomboid fuel assemblies. Power is controlled by six manual boron-stainless steel blade-type control rods and one aluminum with cadmium control rod which can be placed on automatic control. Light water flows upwards through the core and a tank of heavy water surrounds the core. A wall of dense concrete that serves as shielding surrounds the tank of heavy water. The maximum coolant temperature is . The light water and heavy water are cooled using forced circulation through heat exchangers to a secondary coolant system. The heat from the reactor is ultimately dissipated to the atmosphere via the secondary cooling system using two modular Tower Tech cooling towers – model TTXL-081950.
https://en.wikipedia.org/wiki?curid=13419807
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The largest group of contributors to WCRP are several thousands of climate scientists from around the world who offer their expertise and time as volunteers to, for example, help organize workshops in key areas of research, lay out avenues for future research in white paper articles, and serve on WCRP science or advisory boards. Official scientific guidance for the programme is provided by a Joint Scientific Committee (JSC) consisting of 18 volunteer scientists selected by mutual agreement between the three sponsoring organizations. Everyday operations are supported by a secretariat of around 8 full-time staff, hosted by the World Meteorological Organization in Geneva.
https://en.wikipedia.org/wiki?curid=478774
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