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Hepatitis C virus is predominantly a blood-borne virus, with very low risk of sexual or vertical transmission. Because of this mode of spread the key groups at risk are intravenous drug users (IDUs), recipients of blood products and sometimes patients on haemodialysis. Common setting for transmission of HCV is also intra-hospital (nosocomial) transmission, when practices of hygiene and sterilization are not correctly followed in the clinic. A number of cultural or ritual practices have been proposed as a potential historical mode of spread for HCV, including circumcision, genital mutilation, ritual scarification, traditional tattooing and acupuncture. It has also been argued that given the extremely prolonged periods of persistence of HCV in humans, even very low and undetectable rates of mechanical transmission via biting insects may be sufficient to maintain endemic infection in the tropics, where people receive large number of insect bites.
https://en.wikipedia.org/wiki?curid=790967
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HandWritten Address Interpretation is a software system developed at CEDAR. Known as HWAI, it was first deployed by the United States Postal Service through its contractor Lockheed-Martin in Tampa, Florida during the holiday December season in 1997. Initially 10% of the handwritten mail was successfully sorted and the project was considered a success. This was due to the large volume of mail that the US Postal Service processes and the cost of labor involved. The key to the success was the discovery of a heuristic by researchers Sargur Srihari and Jonathan Hull that the street number and ZIP code could be relatively easily recognized, because they only consist of numerals, which could then be used to constrain the possible street. Subsequent improvements to HWAI led to a 45% sort rate with a 2% error rate. Today more than 95% of the handwritten mail is sorted automatically. Versions of HWAI were developed for Australia Post and UK Royal Mail.
https://en.wikipedia.org/wiki?curid=29467953
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The use of the term "shamateurism" apparently originated during the English tour of Australia in 1887–88, a venture from which certain amateurs, notably George Vernon, Andrew Stoddart and Walter Read, were known to be profiting. Long before that, the Grace brothers had been notorious for submitting excessive expense claims but, when an official enquiry was held into their activities in January 1879, the outcome was an official whitewash and they continued to profit. In the 20th century, there were cases of amateur players being given a nominal job, such as county club assistant secretary. Sometimes, there were allegations of surreptitiously paid bonuses over and above the "bona fide" travelling and hotel expenses that they were entitled to claim.
https://en.wikipedia.org/wiki?curid=30187735
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Although Lenin was not an enthusiast for avant garde art, the Vkhutemas faculty and students made projects to honor him and further his politics. Ivan Leonidov's final project at Vkhutemas was his design for a "Lenin Institute of Librarianship". A model of Vladimir Tatlin's "Monument to the Third International" was built by students and displayed at their workshop in Saint Petersburg. Furthermore, "Lenin's Mausoleum" was designed by faculty member Aleksey Shchusev. Alexei Gan's book "Constructivism", published in 1922, provided a theoretical link between the new emerging art and contemporary politics, connecting constructivism with the revolution, and Marxism. The founding decree included a statement that students have an "obligatory education in political literacy and the fundamentals of the communist world view on all courses". These examples help justify the school's projects in terms of the early political requirements but others would arise throughout the school's existence.
https://en.wikipedia.org/wiki?curid=3014315
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The principles of thermodynamics are so well established, both theoretically and experimentally, that proposals for perpetual motion machines are universally met with disbelief on the part of physicists. Any proposed perpetual motion design offers a potentially instructive challenge to physicists: one is certain that it cannot work, so one must explain "how" it fails to work. The difficulty (and the value) of such an exercise depends on the subtlety of the proposal; the best ones tend to arise from physicists' own thought experiments and often shed light upon certain aspects of physics. So, for example, the thought experiment of a Brownian ratchet as a perpetual motion machine was first discussed by Gabriel Lippmann in 1900 but it was not until 1912 that Marian Smoluchowski gave an adequate explanation for why it cannot work. However, during that twelve-year period scientists did not believe that the machine was possible. They were merely unaware of the exact mechanism by which it would inevitably fail.
https://en.wikipedia.org/wiki?curid=54077
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Hertz helped establish the photoelectric effect (which was later explained by Albert Einstein) when he noticed that a charged object loses its charge more readily when illuminated by ultraviolet radiation (UV). In 1887, he made observations of the photoelectric effect and of the production and reception of electromagnetic (EM) waves, published in the journal Annalen der Physik. His receiver consisted of a coil with a spark gap, whereby a spark would be seen upon detection of EM waves. He placed the apparatus in a darkened box to see the spark better. He observed that the maximum spark length was reduced when in the box. A glass panel placed between the source of EM waves and the receiver absorbed UV that assisted the electrons in jumping across the gap. When removed, the spark length would increase. He observed no decrease in spark length when he substituted quartz for glass, as quartz does not absorb UV radiation. Hertz concluded his months of investigation and reported the results obtained. He did not further pursue investigation of this effect, nor did he make any attempt at explaining how the observed phenomenon was brought about.
https://en.wikipedia.org/wiki?curid=13445
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Despite being chosen, the design was still lacking and drew frequent criticism from Wolfram von Richthofen. Testing of the V4 prototype (A Ju 87 A-0) in early 1937 revealed several problems. The Ju 87 could take off in and climb to in eight minutes with a bomb load, and its cruising speed was . Richthofen pushed for a more powerful engine. According to the test pilots, the Heinkel He 50 had a better acceleration rate, and could climb away from the target area much more quickly, avoiding enemy ground and air defences. Richthofen stated that any maximum speed below was unacceptable for those reasons. Pilots also complained that navigation and powerplant instruments were mixed together, and were not easy to read, especially in combat. Despite this, pilots praised the aircraft's handling qualities and strong airframe.
https://en.wikipedia.org/wiki?curid=16590
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NSRL researchers employ the unique Electron Beam Ion Source (EBIS) and the Alternating Gradient Synchrotron's Booster Accelerator to deliver heavy ion beams to a variety of biological specimens (tissues, cells, DNA in-solution), electronic equipment, and new materials to be used in space missions. This beam source allows the facility to change the ion that is being accelerated within 5 minutes and has led to a standardized beam delivery format among NSRL biology experimenters called the "GCR Simulator". This program combines a series of beams, from H to Fe, of various energies, which mimics the absorbed dose to living issue over a period of time during beyond Earth orbit missions.
https://en.wikipedia.org/wiki?curid=36542625
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During their childless marriage, she painted only sporadically and spent most of her time supporting her husband's career, entertaining guests and students, and faithfully backing him in his difficult times with the academy, even when some members of her family aligned against Eakins. She and Eakins both shared a passion for photography, both as photographers and subjects, and employed it as a tool for their art. She also posed nude for many of his photos and took images of him. Both had separate studios in their home. After Eakins' death in 1916, she returned to painting, adding considerably to her output right up to the 1930s, in a style that became warmer, looser, and brighter in tone. She died in 1938. Thirty-five years after her death, in 1973, she had her first one-woman exhibition at the Pennsylvania Academy of Fine Arts.
https://en.wikipedia.org/wiki?curid=102300
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The Archard wear equation is a simple model used to describe sliding wear and is based on the theory of asperity contact. The Archard equation was developed much later than (sometimes also known as energy dissipative hypothesis), though both came to the same physical conclusions, that the volume of the removed debris due to wear is proportional to the work done by friction forces. Theodor Reye's model became popular in Europe and it is still taught in university courses of applied mechanics. Until recently, Reye's theory of 1860 has, however, been totally ignored in English and American literature where subsequent works by Ragnar Holm and John Frederick Archard are usually cited. In 1960, and Mikhail Alekseevich Babichev published a similar model as well. In modern literature, the relation is therefore also known as Reye–Archard–Khrushchov wear law. In 2022, the steady-state Archard wear equation was extended into the running-in regime using the bearing ratio curve representing the initial surface topography.
https://en.wikipedia.org/wiki?curid=11054533
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The assumption that mental operations can be measured by the time required to perform them is considered foundational to modern cognitive psychology. To understand how different brain systems acquire, process and respond to stimuli through the time course of information processing by the nervous system, experimental psychologists often use response times as a dependent variable under different experimental conditions. This approach to the study of mental chronometry is typically aimed at testing theory-driven hypotheses intended to explain observed relationships between measured RT and some experimentally manipulated variable of interest, which often make precisely formulated mathematical predictions.
https://en.wikipedia.org/wiki?curid=4778196
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Rudolf Virchow, a German physician writing during the 1800s, was a key founder of social medicine. In addition to writing in the areas of anthropology and medical science, his contributions to social medicine centered on his recognition of the multiple interacting factors, particularly social factors, that produce disease and illness. He argued that the difficult circumstances and deprivations of the working class increase susceptibility to disease as well as to higher mortality rates. Virchow also recognized the political and material circumstances that inhibited disease prevention efforts and viewed advocacy as an essential part of medical research. He was perhaps most articulate about the limitations of medical science to improving health in the absence of material security. Virchow viewed the state as responsible for providing that security through employment of those who could work. His appreciation for the complex relationship among health, medicine and society are remembered in his statement, “Medicine is a social science, and politics is nothing more than medicine in larger scale”.
https://en.wikipedia.org/wiki?curid=11177972
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In clinical trials, patients are stratified according to their social and individual backgrounds, or any factor that are relevant to the study, to match each of these groups within the entire patient population. The aim of such is to create a balance of clinical/prognostic factor as the trials would not produce valid results if the study design is not balanced. The step of stratified randomization is extremely important as an attempt to ensure that no bias, delibrate or accidental, affects the representative nature of the patient sample under study. It increases the study power, especially in small clinical trials(n<400), as these known clinical traits stratified are thought to effect the outcomes of the interventions. It helps prevent the occurrence of type I error, which is valued highly in clinical studies. It also has an important effect on sample size for active control equivalence trials and in theory, facilitates subgroup analysis and interim analysis.
https://en.wikipedia.org/wiki?curid=63588277
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At GRMH, Professor Donald and Dr. James Willocks then refined their techniques to obstetric applications including fetal head measurement to assess the size and growth of the fetus. With the opening of the new Queen Mother's Hospital in Yorkhill in 1964, it became possible to improve these methods even further. Dr. Stuart Campbell's pioneering work on fetal cephalometry led to it acquiring long-term status as the definitive method of study of foetal growth. As the technical quality of the scans was further developed, it soon became possible to study pregnancy from start to finish and diagnose its many complications such as multiple pregnancy, fetal abnormality and "placenta praevia". Diagnostic ultrasound has since been imported into practically every other area of medicine.
https://en.wikipedia.org/wiki?curid=143357
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In 1967, the Torrey canyon incident off the coast of Britain leaked massive amounts of oil into the ocean. Among the many issues this incident highlighted, was the issue with economic compensation. As the existing laws did not allow the British and French government to sue the responsible corporation for adequate compensation. Today, there are several regulations, such as the clean water act, and International Convention on Civil Liability for Oil Pollution Damage (CLC) that provide a framework for how to deal with the issue of compensation. The regulations aim to identify who is the responsible party, what are damages they must compensate for, and who are the parties should receive compensation.  There are also non-government organizations that deal with oil spill compensation claims, like the international tanker owners pollution federation Limited (ITOPF), a non-profit organization. Though international regulations, like CLC exists and are widely adopted, they do not apply everywhere. The U.S for example, have contributed to the creation of the CLC, but is not a signatory of the CLC because they have extensive national regulations, like the clean water act and oil pollution act that they rely on instead, while China only has implemented parts of it.
https://en.wikipedia.org/wiki?curid=27663682
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Amino acids are a key nutrient in ecosystems. Some are essential to animals, meaning that these organisms cannot synthesize them "de novo". Instead, animals rely on their diet to acquire these molecules, creating strong interdependencies between animals and organisms with complete amino acid synthesis capabilities. In a study of bacteria and archaea at Antarctica's McMurdo Dry Valleys, the distribution of C between their amino acids reflected the biosynthetic pathways employed by these organisms. Autotrophs and heterotrophs had distinct isotopic fingerprints, as did organisms that employed alternatives to the citric acid cycle to ferment or produce acetate. Plants, fungi, and bacteria are also distinguishable by their amino acid carbon isotopes. The compositions of the essential amino acids, which have more complex biosynthetic pathways, are particularly informative. Lysine, isoleucine, leucine, threonine, and valine all had significantly different δC values between at least two of these groups. It is important to note that the fungi and bacteria in this study were grown on amino acid-free media to ensure that all the amino acids were synthesized by the organisms of interest. Bacteria and fungi can also scavenge amino acids from the environment, complicating the interpretation of data from field samples. Nevertheless, researchers have successfully used these differences to identify the sources of amino acids in food webs. Terrestrial and marine producers in a mangrove forest had different patterns of C enrichment in their amino acids. Fishes from a coral reef with diets containing different carbon sources also had variable amino acid δC values. Furthermore, one study observed distinct amino acid isotopic compositions for desert C, C, and CAM plants. These applications in diverse ecosystems highlight the versatility of compound-specific amino acid isotope analysis.
https://en.wikipedia.org/wiki?curid=70659220
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This loss is minimized by allowing the rotor to rotate very quickly. To the observer it may seem like the rotor is not moving fast; however, it is common for the tips to be moving through the air at 8-10 times the speed of the free stream. Newtonian mechanics defines power as torque multiplied by the rotational speed. The same amount of power can be extracted by allowing the rotor to rotate faster and produce less torque. Less torque means that there is less wake rotation. Less wake rotation means there is more energy available to extract. However, very high tip speeds also increase the drag on the blades, decreasing power production. Balancing these factors is what leads to most modern horizontal-axis wind turbines running at a tip speed ratio around 9. In addition, wind turbines usually limit the tip speed to around 80-90m/s due to leading edge erosion and high noise levels. At wind speeds above about 10m/s (where a turbine running a tip speed ratio of 9 would reach 90m/s tip speed), turbines usually do not continue to increase rotational speed for this reason, which slightly reduces efficiency.
https://en.wikipedia.org/wiki?curid=20876989
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On 19 December 1941, "Queen Elizabeth" and her sister ship were seriously damaged by limpet mines placed by Italian combat swimmers of Decima Flottiglia MAS, who entered the Allied military port of Alexandria with SLC type "manned torpedoes" (""maiali""). Although badly damaged, with her draught increased to 41.8 feet (12.5m), "Queen Elizabeth" was not grounded on the harbour bottom, her decks were clear and the Italian crews were captured. For this reason, the Royal Navy maintained the illusion of full operational status, to conceal their weakened position in the Mediterranean during the period the two ships were repaired and refloated. "Valiant" went back into service after many months and "Queen Elizabeth" after more than a year and a half. Following completion of temporary repairs in an Alexandria drydock in June 1942, she steamed through the Suez Canal and around Africa to the Navy Yard in Norfolk, Virginia, in the United States. From September 1942 until June 1943, she was comprehensively repaired. "Queen Elizabeth" went to the Home Fleet in July 1943.
https://en.wikipedia.org/wiki?curid=485634
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How traffic signals are designed and implemented directly impacts cyclists. For instance, poorly adjusted vehicle detector systems, used to trigger signal changes, may not correctly detect cyclists. This can leave cyclists in the position of having to "run" red lights if no motorized vehicle arrives to trigger a signal change. Some cities use urban adaptive traffic control systems (UTCs), which use linked traffic signals to manage traffic in response to changes in demand. There is an argument that using a UTC system merely to provide for increased capacity for motor traffic will simply drive growth in such traffic. However, there are more direct negative impacts. For instance, where signals are arranged to provide motor traffic with so-called green waves, this can create "red waves" for other road users such as cyclists and public transport services. Traffic managers in Copenhagen have now turned this approach on its head and are linking cyclist-specific traffic signals on a major arterial bike lane to provide green waves for rush hour cycle-traffic. However, this would still not resolve the problem of red-waves for slow (old and young) and fast (above average fitness) cyclists. Cycling-specific measures that can be applied at traffic signals include the use of advanced stop lines and/or bypasses. In some cases cyclists might be given a free-turn or a signal bypass if turning into a road on the nearside.
https://en.wikipedia.org/wiki?curid=33466720
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Human βTrCP (referred to both βTrCP1 and βTrCP2) was originally identified as a cellular ubiquitin ligase that is bound by the HIV-1 Vpu viral protein to eliminate cellular CD4 by connecting it to the proteolytic machinery. Subsequently, βTrCP was shown to regulate multiple cellular processes by mediating the degradation of various targets. Cell cycle regulators constitute a major group of βTrCP substrates. During S phase, βTrCP keeps CDK1 in check by promoting the degradation of the phosphatase CDC25A, whereas in G2, βTrCP contributes to CDK1 activation by targeting the kinase WEE1 for degradation. In early mitosis, βTrCP mediates the degradation of EMI1, an inhibitor of the APC/C ubiquitin ligase complex, which is responsible for the anaphase-metaphase transition (by inducing the proteolysis of Securin) and mitotic exit (by driving the degradation of mitotic CDK1 activating cyclin subunits). Furthermore, βTrCP controls APC/C by targeting REST, thereby removing its transcriptional repression on MAD2, an essential component of the spindle assembly checkpoint that keeps APC/C inactive until all chromatids are attached to the spindle microtubules.
https://en.wikipedia.org/wiki?curid=14723112
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The 2d FIS converted to F-102 Delta Daggers in January 1957, followed by the 5th FIS in April. In December 1959, the 2d FIS began to fly F-101 Voodoos, while the 5th FIS retained its F-102s until moving to Minot Air Force Base, North Dakota two months later. The group served as an air defense unit in the New York/New Jersey area of the United States and also flew anti-submarine warfare missions until being inactivated in 1963 and replaced as the host unit at Suffolk County by the 52d Fighter Wing (Air Defense). In 1968, as USAF operations at Suffolk County were reduced, it once again activated with F-101s to replace the 52d wing and close down USAF operations at the station in 1969.
https://en.wikipedia.org/wiki?curid=23168422
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The criticism was soon afterwards made, that both Adams and Le Verrier had been over-optimistic in the precision they claimed for their calculations, and both had, by using Bode's law, greatly overestimated the planet's distance from the sun. Further, it was suggested that they both succeeded in getting the longitude almost right only because of a "fluke of orbital timing". This criticism was discussed in detail by Danjon (1946) who illustrated with a diagram and discussion that while hypothetical orbits calculated by both Le Verrier and Adams for the new planet were indeed of very different size on the whole from that of the real Neptune (and actually similar to each other), they were both much closer to the real Neptune over that crucial segment of orbit covering the interval of years for which the observations and calculations were made, than they were for the rest of the calculated orbits. So the fact that both the calculators used a much larger orbital major axis than the reality was shown to be not so important, and not the most relevant parameter.
https://en.wikipedia.org/wiki?curid=13002123
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The Hoba ( ) meteorite, short for Hoba West, is a meteorite that lies on the farm of the same name, not far from Grootfontein, in the Otjozondjupa Region of Namibia. It has been uncovered, but because of its large mass, has never been moved from where it fell. The main mass is estimated at more than 60 tonnes. It is the largest known intact meteorite (as a single piece) and about twice as massive as the largest fragment of either the Cape York meteorite's 31-tonne Ahnighito kept in Manhattan or the Campo del Cielo's 31-tonne Gancedo in Argentina. It is also the most massive naturally occurring piece of iron (actually ferronickel) known on Earth's surface. The name "Hoba" comes from a Khoekhoegowab word meaning "gift". Following donation to the government in 1987, a visitor centre was constructed with a circular stone access and seating area.
https://en.wikipedia.org/wiki?curid=3858734
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This represented deep-rooted British political and strategic ideas. The war had left Britain impoverished. Its gold and dollar reserves had been depleted. A third of its merchant ships now lay on the bottom of the ocean. About 250,000 homes had been destroyed and another 3 million had been damaged while hardly any had been built for years. In early 1947, factories suspended production for want of coal. The United States had abruptly terminated Lend-Lease when the war ended. In its place was a $3.75 billion loan from the United States and a $1.25 billion loan from Canada, most of which had been spent by August 1947. Nonetheless, there remained an implacable belief that the future would be like the past. Bevin told the House of Commons on 16 May 1947 that:
https://en.wikipedia.org/wiki?curid=52573493
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The kinetic energy dissipated by aerobraking is converted to heat, meaning that spacecraft must dissipate this heat. The spacecraft must have sufficient surface area and structural strength to produce and survive the required drag, The temperatures and pressures associated with aerobraking are not as severe as those of atmospheric reentry or aerocapture. Simulations of the "Mars Reconnaissance Orbiter" aerobraking use a force limit of 0.35 N per square meter with a spacecraft cross section of about 37 m, equate to a maximum drag force of about 7.4 N, and a maximum expected temperature as 170 °C. The force density (i.e. pressure), roughly 0.2 N per square meter, that was exerted on the "Mars Observer" during aerobraking is comparable to the aerodynamic resistance of moving at 0.6 m/s (2.16 km/h) at sea level on Earth, approximately the amount experienced when walking slowly.
https://en.wikipedia.org/wiki?curid=140289
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Essentially, if a nuclear material has been put through a refinement process to remove the daughter species, the time elapsed since purification can be "back-calculated" using radiochemical separation techniques in conjunction with analytical measurement of the existing parent-daughter ratios. For example, the α decay of Pu to U can be used as an example of this procedure. with the assumption of a perfect purification time "T" then there will be a linear relationship between the in-growth of U and time elapsed since purification. There are, however, various instances where the correlation is not as clear. This strategy may not apply when the parent-daughter pair achieve secular equilibrium very rapidly or when the half-life of the daughter nuclide is significantly shorter than the time that has elapsed since purification of the nuclear material, e.g. Np/Pa. Another possible complication is if in environmental samples, non-equivalent metal/ion transport for parents and daughter species may complicate or invalidate the use of chronometric measurements. Special age-dating relationships exist, including the commonly employed U/Th and Pu/Am chronometers. In special circumstances, parent-granddaughter relationships can be used to elucidate the age of nuclear materials when the material is intentionally made to look older through the addition of daughter nuclides.
https://en.wikipedia.org/wiki?curid=36022927
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An interview with Robert Salter appeared in the "Los Angeles Times" (June 11, 1972). He discussed, in detail, the relative ease with which the U.S. government could build a tube shuttle system using technologies available at that time. Maglev being poorly developed at the time, he proposed steel wheels. The chamber's door to the tube would be opened, and enough air admitted behind to accelerate the train into the tube. Gravity would further accelerate the departing train down to cruise level. Rising from cruise level, the arriving train would decelerate by compressing the rarefied air ahead of it, which would be vented. Pumps at the stations would make up for losses due to friction or air escaping around the edges of the train, the train itself requiring no motor. This combination of modified (shallow) gravity train and atmospheric railway propulsion would consume little energy but limit the system to subsonic speeds, hence initial routes of tens or hundreds of miles or kilometers rather than transcontinental distances were proposed.
https://en.wikipedia.org/wiki?curid=3294173
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Diagnostic efforts then shift to determining the type- elevated ammonia levels or abnormal organic acids can indicate specific, rare types. Intrauterine growth retardation and other perinatal problems raise the possibility of transience, while large birthweight suggests one of the more persistent conditions. Genetic screening is now available within a useful time frame for some of the specific conditions. It is worthwhile to identify the minority of severe cases with focal forms of hyperinsulinism because these can be completely cured by partial pancreatectomy. A variety of pre-operative diagnostic procedures have been investigated but none has been established as infallibly reliable. Positron emission tomography is becoming the most useful imaging technique.
https://en.wikipedia.org/wiki?curid=1306596
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Hamer argues that human sexuality can and should be studied scientifically and discusses his findings about Xq28, a region of the X chromosome. According to Hamer, he shifted his area of research from metallothionein to the genetics of homosexuality after reading the naturalist Charles Darwin's "The Descent of Man, and Selection in Relation to Sex" (1871) and the evolutionary geneticist Richard Lewontin, the neurobiologist Steven Rose and the psychologist Leon Kamin's "Not in Our Genes" (1984). Hamer writes that Darwin's book surprised him because of the amount of space it devotes to discussing sexual selection. He describes Lewontin "et al."′s work as "a political rather than a scientific book" and expresses his disagreement with its politics. However, he comments that it taught him that the genetics of behavior is an emotionally and politically charged topic, especially where it concerns sexuality. He criticizes Alfred Kinsey, as well as Sigmund Freud and his views on homosexuality.
https://en.wikipedia.org/wiki?curid=55800745
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Gerbrand Ceder is a Belgian-American scientist who is the Daniel M. Tellep Distinguished Professor of Materials Science and Engineering at University of California, Berkeley. He is notable for his pioneering research in high-throughput computational materials design, and in the development of novel lithium-ion battery technologies. He is co-founder of the Materials Project, an open-source online database of "ab initio" calculated material properties, which inspired the Materials Genome Initiative by the Obama administration in 2011. He is also the Founder and CTO of Pellion Technologies (previously CEO), which aims to commercialize magnesium-ion batteries. In 2017 Gerbrand Ceder was elected a member of the National Academy of Engineering, "For the development of practical computational materials design and its application to the improvement of energy storage technology."
https://en.wikipedia.org/wiki?curid=47017813
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Elizabeth Russell Miller (February 26, 1939 – January 2, 2022) was a Professor Emerita at Memorial University of Newfoundland. She resided in Toronto. In her early academic career, she focused on Newfoundland literature, primarily the life and work of her father, well-known Newfoundland author and humorist Ted Russell. Since 1990, her major field of research has been Bram Stoker's novel "Dracula", its author, sources and influence. She has published several books on the subject, including "Reflections on Dracula", "Dracula: Sense & Nonsense", a volume on Dracula for the "Dictionary of Literary Biography" and, most recently, "Bram Stoker's Notes for Dracula: A Facsimile Edition" with Robert Eighteen-Bisang. She founded the Dracula Research Centre (now offline) and was the founding editor of the "Journal of Dracula Studies" now at Kutztown University of Pennsylvania.
https://en.wikipedia.org/wiki?curid=22493000
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Xe isotopes are also promising in tracing mantle dynamics in Earth's evolution. The first explicit recognition of non-atmospheric Xe in terrestrial samples came from the analysis of CO-well gas in New Mexico, displaying an excess of I-derived or primitive source Xe and high content in Xe due to the decay of U. At present, the excess of Xe and Xe has been widely observed in mid-ocean ridge basalt (MORBs) and Oceanic island basalt (OIBs). Because Xe receives more fissiogenic contribution than other heavy Xe isotopes, Xe (decay of I) and Xe are usually normalized to Xe when discussing Xe isotope trends of different mantle sources. MORBs' Xe/Xe and Xe/Xe ratios lie on a trend from atmospheric ratios to higher values and seemingly contaminated by the air. Oceanic island basalt (OIBs) data lies lower than those in MORBs, implying different Xe sources for OIBs and MORBs.
https://en.wikipedia.org/wiki?curid=70939631
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The power conversion efficiency of a solar cell is usually determined by characterizing its current-voltage (IV) behavior under simulated solar illumination. In contrast to other solar cells, however, it has been observed that the IV-curves of perovskite solar cells show a hysteretic behavior: depending on scanning conditions – such as scan direction, scan speed, light soaking, biasing – there is a discrepancy between the scan from forward-bias to short-circuit (FB-SC) and the scan from short-circuit to forward bias (SC-FB). Various causes have been proposed such as ion movement, polarization, ferroelectric effects, filling of trap states, however, the exact origin for the hysteretic behavior is yet to be determined. But it appears that determining the solar cell efficiency from IV-curves risks producing inflated values if the scanning parameters exceed the time-scale which the perovskite system requires in order to reach an electronic steady-state. Two possible solutions have been proposed: Unger et al. show that extremely slow voltage-scans allow the system to settle into steady-state conditions at every measurement point which thus eliminates any discrepancy between the FB-SC and the SC-FB scan.
https://en.wikipedia.org/wiki?curid=43845714
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Dosing of warfarin is complicated because it is known to interact with many commonly used medications and certain foods. These interactions may enhance or reduce warfarin's anticoagulation effect. To optimize the therapeutic effect without risking dangerous side effects such as bleeding, close monitoring of the degree of anticoagulation is required by a blood test measuring an INR. During the initial stage of treatment, INR is checked daily; intervals between tests can be lengthened if the patient manages stable therapeutic INR levels on an unchanged warfarin dose. Newer point-of-care testing is available and has increased the ease of INR testing in the outpatient setting. Instead of a blood draw, the point-of-care test involves a simple finger prick.
https://en.wikipedia.org/wiki?curid=238097
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The choice of the various parameters formula_59 and formula_46 for formula_61 and a certain mean depth formula_52 determines the form of the ocean surface. A clever choice is needed in order to exploit the possibility of fast computation by means of the FFT. See e.g. for a description how to do this. Most often, the wavenumbers are chosen on a regular grid in formula_63-space. Thereafter, the amplitudes formula_44 and phases formula_46 are chosen randomly in accord with the variance-density spectrum of a certain desired sea state. Finally, by FFT, the ocean surface can be constructed in such a way that it is periodic both in space and time, enabling tiling – creating periodicity in time by slightly shifting the frequencies formula_48 such that formula_67 for formula_68
https://en.wikipedia.org/wiki?curid=46455334
1,179,273
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The bristle-thighed curlew was formally described in 1789 by the German naturalist Johann Friedrich Gmelin in his revised and expanded edition of Carl Linnaeus's "Systema Naturae". He placed it in the genus "Scolopax" and coined the binomial name "Scolopax tahitiensis". Gmelin based his description on the "Otaheite curlew" that had been described in 1785 by the English ornithologist John Latham in his "A General Synopsis of Birds". "Otaheite" is a former name of Tahiti. The specimen used by Latham was supplied by the naturalist Joseph Banks. Banks had accompanied James Cook on his first voyage to the south Pacific but had also received specimens from Cook's subsequent voyages. The bristle-thighed curlew is now one of nine species placed in the genus "Numenius" that was erected in 1760 by the French scientist Mathurin Jacques Brisson in his "Ornithologie". The name "Numenius" is from Ancient Greek "noumenios", a bird mentioned by Hesychius. It is associated with the curlews because it appears to be derived from "neos", "new" and "mene" "moon", referring to the crescent-shaped bill. The species is considered to be monotypic: no subspecies are recognised.
https://en.wikipedia.org/wiki?curid=1598629
1,282,460
1,713,449
Since the advent of GPS and other satellite navigation systems, highly precise, yet affordable timing is available from many commercial GNSS receivers. Its initial system design expected general timing precision better than 340 nanoseconds using low-grade "coarse mode" and 200 ns in precision mode. A GPS receiver functions by precisely measuring the transit time of signals received from several satellites. These distances combined geometrically with precise orbital information identify the location of the receiver. Precise timing is fundamental to an accurate GPS location. The time from an atomic clock onboard each satellite is encoded into the radio signal; the receiver determines how much later it received the signal than it was sent. To do this, a local clock is corrected to the GPS atomic clock time by solving for three dimensions and time based on four or more satellite signals. Improvements in algorithms lead many modern low-cost GPS receivers to achieve better than 10-meter accuracy, which implies a timing accuracy of about 30 ns. GPS-based laboratory time references routinely achieve 10 ns precision.
https://en.wikipedia.org/wiki?curid=144485
1,712,483
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These are three views of Mare Tranquillitatis on the Moon, taken by the mapping camera of the Apollo 17 mission in 1972, facing south-southwest from an average altitude of 111 km on Revolution 36 of the mission. At the left is the east side of Mare Tranquillitatis, with the craters Franz (bottom right), Lyell (dark floor, right of center), and Taruntius (upper left). The "bay" of dark mare (basalt) at left is Sinus Concordiae, with "islands" of older, light highland material. At the right is the crater Cauchy, which lies between the Rupes Cauchy and Cauchy rille. The center photo shows the central mare with craters Vitruvius (lower right) and Gardner (bottom center). At the horizon are lighter highlands at the southern margin of the mare, near the Apollo 11 landing site. The crater Jansen is visible at the edges of both the center and right photos. The right photo shows the western mare, with the craters Dawes (lower left) and the large Plinius (43 km diameter), with the Plinius Rilles in the foreground. These photos were taken within minutes of each other as the command module "America" orbited the Moon. The Sun elevation drops from 46 degrees at left to 30 degrees at right.
https://en.wikipedia.org/wiki?curid=201573
767,643
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The Storm Water Management Model Climate Adjustment Tool (SWMM-CAT) is a new addition to SWMM5 (December 2014). It is a simple to use software utility that allows future climate change projections to be incorporated into the Storm Water Management Model (SWMM). SWMM was recently updated to accept a set of monthly adjustment factors for each of these time series that could represent the impact of future changes in climatic conditions. SWMM-CAT provides a set of location-specific adjustments that derived from global climate change models run as part of the World Climate Research Programme (WCRP) Coupled Model Intercomparison Project Phase 3 (CMIP3) archive (Figure 4). SWMM-CAT is a utility that adds location-specific climate change adjustments to a Storm Water Management Model (SWMM) project file. Adjustments can be applied on a monthly basis to air temperature, evaporation rates, and precipitation, as well as to the 24-hour design storm at different recurrence intervals. The source of these adjustments are global climate change models run as part of the World Climate Research Programme (WCRP) Coupled Model Intercomparison Project Phase 3 (CMIP3) archive. Downscaled results from this archive were generated and converted into changes with respect to historical values by USEPA's CREAT project.
https://en.wikipedia.org/wiki?curid=3429879
1,414,839
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Nixon closed his statement, "Mankind already carries in its own hands too many of the seeds of its own destruction. By the examples we set today, we hope to contribute to an atmosphere of peace and understanding between nations and among men." Shortly after Nixon's statement the United States and the Soviet Union began the SALT arms control talks, which eventually resulted in nuclear arms controls as well as the 1972 Antiballistic Missile Treaty. The U.S. commitment to end BW programs helped provide the lead for ongoing talks led by the United Kingdom in Geneva. The Eighteen Nation Disarmament Committee was discussing a British draft of a biological weapons treaty which the United Nations General Assembly approved in 1968 and that NATO supported. These arms control talks would eventually lead to the Biological Weapons Convention, an international treaty outlawing biological warfare.
https://en.wikipedia.org/wiki?curid=20791072
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The programme immediately ran into problems. On 7 May 1969, Minister of Defence for Equipment Sir John Morris in Parliament claimed that the Blowpipe's development was "...proceeding satisfactorily but is at too early a stage for any firm production order." Two years later, on 11 February 1971, Minister of State for Defence Robert Lindsay noted that "The development programme for this missile continues to make progress although it will still be some time before it is completed. It would be contrary to normal policy to give detailed forecasts of the Forces' production requirements." On 16 March 1972, Under-Secretary for Defence for the Army Geoffrey Johnson-Smith said of Blowpipe "This is now in an advanced stage of development and some successful trials with it have been carried out. It, too, should be in service in about two years' time."
https://en.wikipedia.org/wiki?curid=315571
1,005,423
1,109,529
The Changi Military Railway was a 4-mile long standard gauge line built by the FMSR for the War Department, for the protection of Singapore's new Naval Base at Sembawang. The fortifications for the Naval Base were laid at the entrance to the Old Strait, at Changi, where one 15-inch gun, one 9-inch battery, one 6-inch battery and search lights were installed. The artillery installations were supplied with underground ammunition depots and loaded with armour piercing shells. On the beach, concrete machine emplacements and wire were installed. Airfields in Sembawang, Seletar and Tengah were to provide air cover for the Base. Bagnalls of Stafford supplied an 0-6-0ST, number 2547 of 6/1936, to the War Office department, Changi, Singapore. It had 16" x 22" cylinders and 3' 4" driving wheels. It was last seen derelict in 1947 but its fate is unknown. The railway ran from Fairy Point pier to the battery with a short branch to a depot.
https://en.wikipedia.org/wiki?curid=2364123
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Across different cultures deviations from the Strange Situation Protocol have been observed. A Japanese study in 1986 (Takahashi) studied 60 Japanese mother-infant pairs and compared them with Ainsworth's distributional pattern. Although the ranges for securely attached and insecurely attached had no significant differences in proportions, the Japanese insecure group consisted of only resistant children, with no children categorized as avoidant. This may be because the Japanese child rearing philosophy stressed close mother infant bonds more so than in Western cultures. In Northern Germany, Grossmann et al. (Grossmann, Huber, & Wartner, 1981; Grossmann, Spangler, Suess, & Unzner, 1985) replicated the Ainsworth Strange Situation with 46 mother infant pairs and found a different distribution of attachment classifications with a high number of avoidant infants: 52% avoidant, 34% secure, and 13% resistant (Grossmann et al., 1985). Another study in Israel found there was a high frequency of an ambivalent pattern, which according to Grossman et al. (1985) could be attributed to a greater parental push toward children's independence.
https://en.wikipedia.org/wiki?curid=884589
52,079
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Proper protection such as welding goggles should be worn at all times, including to protect the eyes against glare and flying sparks. Special safety eyewear must be used—both to protect the welder and to provide a clear view through the yellow-orange flare given off by the incandescing flux. In the 1940s cobalt melters’ glasses were borrowed from steel foundries and were still available until the 1980s. However, the lack of protection from impact, ultra-violet, infrared and blue light caused severe eyestrain and eye damage. Didymium eyewear, developed for glassblowers in the 1960s, was also borrowed—until many complained of eye problems from excessive infrared, blue light, and insufficient shading. Today very good eye protection can be found designed especially for gas-welding aluminum that cuts the sodium orange flare completely and provides the necessary protection from ultraviolet, infrared, blue light and impact, according to ANSI Z87-1989 safety standards for a Special Purpose Lens.
https://en.wikipedia.org/wiki?curid=12414930
304,618
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CNAM is based in 160 other French cities. French regional CNAM Centres are independent and autonomous in terms of enrolment and selection of candidates. Half of the regional CNAM centres budget is allocated by the French regional councils. The nearest Frenchregional CNAM should apply in terms of enrolment, in other words, someone living in Marseille should enrol in Marseille and not in Paris, even if his desired curriculum is not available in Marseille. As the vast majority of curricula are taught online, students can attend them from their nearest CNAM regional centre. Shall some specific classes be available only in Paris or at another regionalc centre, the student can attend these courses on-site, shall it be required (for example laboratory sessions in Life Science, Physics or Chemistry). Regional centres providing Engineering diploma via the EiCNAM, the Grande Ecole Engineer School of CNAM are all certified by the French national committee responsible for evaluation and accreditation of higher education institutions for the training of professional engineers in France (in French: "Commission des Titres d'Ingénieur", abbr.: CTI). Some CNAM regional centres are hosted by other partner universities, for example the CNAM centre of Aix-en-Provence is located at the campus of the French Grande Ecole engineering and research school: Arts et Métiers ParisTech.
https://en.wikipedia.org/wiki?curid=434493
1,455,709
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The efficiency of steam prime movers in converting the heat energy of fuel into mechanical work was a critical factor in the economic operation of steam central generating stations. Early projects used reciprocating steam engines, operating at relatively low speeds. The introduction of the steam turbine fundamentally changed the economics of central station operations. Steam turbines could be made in larger ratings than reciprocating engines, and generally had higher efficiency. The speed of steam turbines did not fluctuate cyclically during each revolution; making parallel operation of AC generators feasible, and improved the stability of rotary converters for production of direct current for traction and industrial uses. Steam turbines ran at higher speed than reciprocating engines, not being limited by the allowable speed of a piston in a cylinder. This made them more compatible with AC generators with only two or four poles; no gearbox or belted speed increaser was needed between the engine and the generator. It was costly and ultimately impossible to provide a belt-drive between a low-speed engine and a high-speed generator in the very large ratings required for central station service.
https://en.wikipedia.org/wiki?curid=551731
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A clear distinction is made between the ultimate state (US) and the ultimate limit state (ULS). The US is a physical situation that involves either excessive deformations leading and approaching collapse of the component under consideration or the structure as a whole, as relevant, or deformations exceeding pre-agreed values. It involves, of course, considerable inelastic (plastic) behavior of the structural scheme and residual deformations. In contrast, the ULS is not a physical situation but rather an agreed computational condition that must be fulfilled, among other additional criteria, in order to comply with the engineering demands for strength and stability under design loads. A structure is deemed to satisfy the ultimate limit state criterion if all factored bending, shear and tensile or compressive stresses are below the factored resistances calculated for the section under consideration. The factored stresses referred to are found by applying Magnification Factors to the loads on the section. Reduction Factors are applied to determine the various factored resistances of the section.
https://en.wikipedia.org/wiki?curid=352354
663,449
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The Reed Institute (the legal name of the college) was founded in 1908 and held its first classes in 1911. Reed is named for Oregon pioneers Simeon Gannett Reed (1830–1895) and Amanda Reed (died 1904). Simeon was an entrepreneur involved in several enterprises, including trade on the Willamette and Columbia Rivers with his close friend and associate, former Portland Mayor William S. Ladd (for whom Ladd's Addition is named). Unitarian minister Thomas Lamb Eliot, who knew the Reeds from the church choir, is credited with convincing Reed of the need for "a lasting legacy, a 'Reed Institute of Lectures,' and joked it would 'need a mine to run it.'" Reed's will suggested his wife could "devote some portion of my estate to benevolent objects, or to the cultivation, illustration, or development of the fine arts in the city of Portland, or to some other suitable purpose, which shall be of permanent value and contribute to the beauty of the city and to the intelligence, prosperity, and happiness of the inhabitants". Ladd's son, William Mead Ladd, donated 40 acres from the Ladd Estate Company to build the new college. Reed's first president (1910–1919) was William Trufant Foster, a former professor at Bates College and Bowdoin College in Maine. Prior to coming to Reed, Foster wrote that his ideal college would be one that "combats laziness, superficiality, dissipation, excessive indulgence in college life, by making the moral and intellectual requirements an honest, sustained, and adequate challenge to the best powers of the best American youth."
https://en.wikipedia.org/wiki?curid=25417
256,577
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After satisfactory completion of Accreditation Council for Graduate Medical Education (ACGME) accredited residency program in anesthesiology formal advanced training in Neurosurgical Anesthesia is available as a 1 or 2 -year fellowship integrating research, teaching and clinical experience. Although fellowships differ slightly at various institutions, they generally involve the fellow in participating in 12–24 months of research (either clinical or basic sciences), participation in advanced cases in the neurosurgical O.R.s and interventional radiology suites, and develop experience in performance and interpretation of neuromonitoring. Neurosurgical anesthesia fellows may also rotate in neurosurgical intensive care unit and gain experience with transcranial doppler, basic EEG interpretation and Licox/Microdialysis interpretation. Some institutions also allow the fellow to participate in education and teaching efforts for neurosurgical departments in developing countries.
https://en.wikipedia.org/wiki?curid=28336484
2,005,982
833,358
One of the first teams to build a complete system around the 8008 was Bill Pentz' team at California State University, Sacramento. The "Sac State 8008" was possibly the first true microcomputer, with a disk operating system built with IBM Basic assembly language in PROM, all driving a color display, hard drive, keyboard, modem, audio/paper tape reader and printer. The project started in the spring of 1972, and with key help from Tektronix the system was fully functional a year later. Bill assisted Intel with the MCS-8 kit and provided key input to the Intel 8080 instruction set, which helped make it useful for the industry and hobbyists.
https://en.wikipedia.org/wiki?curid=66039
832,909
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The component that came to be called the LPC has been associated with episodic memory and was first described in ERP studies examining either repetition or recognition effects. In both paradigms, studies found that ERPs to repeated/recognized items differed from those to newly presented ones in several ways. In particular, second presentations of items were associated with increased positivity between 500 and 800 ms post-stimulus onset—an effect that came to be called the LPC. but also referred to as the P300, late positivity or "parietal old/new effect". In one of the earliest examples of such a study, Friedman (1990) presented test items in a continuous recognition paradigm (in which study and test trials are intermingled). Results showed that ERPs to old items were characterized by decreases in an negativity between 300 and 500 ms (N400) and increases in a subsequent, partially overlapping positivity (LPC/P300). The joint increase in positivity across these two responses was termed the "old/new" effect.
https://en.wikipedia.org/wiki?curid=27326557
1,542,558
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With intramuscular administration of 150 mg microcrystalline MPA in aqueous suspension, the medication is detectable in the circulation within 30 minutes, serum concentrations vary but generally plateau at 1.0 ng/mL (2.6 nmol/L) for 3 months. Following this, there is a gradual decline in MPA levels, and the medication can be detected in the circulation for as long as 6 to 9 months post-injection. The particle size of MPA crystals significantly influences its rate of absorption into the body from the local tissue depot when used as a microcrystalline aqueous suspension via intramuscular injection. Smaller crystals dissolve faster and are absorbed more rapidly, resulting in a shorter duration of action. Particle sizes can differ between different formulations of MPA, potentially influencing clinical efficacy and tolerability.
https://en.wikipedia.org/wiki?curid=23484633
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Not all EHEA compliant study programmes in Spain are officially approved and/or accredited by government agencies. Some universities offer proprietary study programmes as an alternative to accredited study programmes for a variety of reasons: attending the continuing education market for individual self-advancement and also providing higher education to individuals that have failed to acquire bachelor's degree qualifications. The main reason for offering this alternative studies, though, is the heavy bureaucratic process that needs to be accomplished to receive the approval of specific titles, in particular when it refers to new studies or studies about matters that do not fit with the official studies. For historical reasons, the academic system has been very much under the control of the State and private universities are still regarded with as a threat to the State system.
https://en.wikipedia.org/wiki?curid=167241
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When Bill Edrich came to the crease, Bradman advised Lindwall not to bowl any bouncers at Edrich, fearing that it would be interpreted as retaliation for Edrich's bouncing of Lindwall in the first innings and lead to a negative media and crowd reaction. Although Lindwall did not retaliate, Miller did so with four consecutive bouncers, earning the ire of the crowd. He struck Edrich on the body before Bradman intervened and ordered him to stop, before apologising to Edrich. England reached 3/174, a lead of 316, at the end of day three, but declared on the fifth morning after the fourth day was washed out. Bradman chose the light roller and play was supposed to begin after lunch. However, play did not begin until after tea and the pitch played very slowly because of the excess moisture. With Australia not looking to chase the runs, Yardley often had seven men in close catching positions. Australia showed little attacking intent and Bradman joined Morris with Australia at 1/10 after 32 minutes.
https://en.wikipedia.org/wiki?curid=21051201
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In sum, mainly the meatier areas were prepared, and the rest discarded. This suggests they were butchering humans for nutritional purposes, but the face generally exhibits significantly more cutmarks than the faces of animals. When this is seen in prehistoric modern human specimens, it is typically interpreted as evidence of exocannibalism, a form of ritual cannibalism where one eats someone from beyond their social group, such as an enemy from a neighbouring tribe. But, when overviewing the evidence of "H. antecessor" cannibalism in 1999, Spanish palaeontologist Yolanda Fernandez-Jalvo and colleagues instead ascribed the relative abundance of facial cut marks in the "H. antecessor" sample to the strongly contrasting structure of the muscle attachments between humans and typical animal prey items (that is, defleshing the human face simply required more cuts, or the butcherers were less familiar with defleshing humans).
https://en.wikipedia.org/wiki?curid=1195815
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Chisholm entered Girton College in 1889 aged 22, four years after she passed the senior entrance examination having been awarded the Sir Francis Goldsmid Scholarship by the college. At this time the college was only associated with the University of Cambridge with men and women graded on separate but related lists. Although she wanted to study medicine, her mother would not permit this, so, supported by her father, she decided to study mathematics. At the end of her first year, when the Mays list came out, she was top of the Second class immediately below Isabel Maddison. In 1893, Grace passed her final examinations with the equivalent of a first-class degree, ranked between 23 and 24 relative to 112 men.
https://en.wikipedia.org/wiki?curid=239997
1,516,814
1,058,660
In July 1975, Alan E. Guskin, acting president of Clark University in Massachusetts, became the second chancellor of UW–Parkside. In Spring 1976, Gary Cole finished his basketball career with a record 2,262 points (20.6 per game) and 1,177 rebounds. Cole, now known as Abdul Jeelani, went on to play for the Portland Trail Blazers and Dallas Mavericks. Around the same time, UW–Parkside race walker Jim Heiring was the university's first to compete in the United States Olympic trials in the 20-kilometer walk, narrowly missing out on a place in the team. He went on to become a six-time national champion and member of the 1980, 1984 and 1988 teams. In October 1976 the $3.7 million student union opened.
https://en.wikipedia.org/wiki?curid=496736
1,058,111
354,098
A gap between the inner and outer Van Allen belts—sometimes called safe zone or safe slot—is caused by the Very Low Frequency (VLF) waves, which scatter particles in pitch angle, which results in the gain of particles to the atmosphere. Solar outbursts can pump particles into the gap, but they drain again in a matter of days. The radio waves were originally thought to be generated by turbulence in the radiation belts, but recent work by James L. Green of the Goddard Space Flight Center—comparing maps of lightning activity collected by the Microlab 1 spacecraft with data on radio waves in the radiation-belt gap from the IMAGE spacecraft—suggests that they are actually generated by lightning within Earth's atmosphere. The generated radio waves strike the ionosphere at the correct angle to pass through only at high latitudes, where the lower ends of the gap approach the upper atmosphere. These results are still under scientific debate.
https://en.wikipedia.org/wiki?curid=59953
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Out-of-universe criticisms focus on the above problems; that the Prime Directive is simply a plot device and is manipulated by the writers. Janet D. Stemwedel points out a potential conflict between the anti-colonialist intentions of the Federation and the "ethical project of sharing a universe" which would require "a kind of reciprocity — even if your technological attainment is quite different, it means recognizing you are owed the same moral consideration." Stemwedel writes, "If your concern is not to change the natural behavior or development of alien citizens at any cost, your best bet is to stay at home rather than to explore new worlds." Ars Technica asked lawyers to comment on the Prime Directive and other "Star Trek" legal issues. Criticism included interpreting the Prime Directive as a product of the Cold War environment in which Roddenberry wrote as well as indicating that enforcement would be lacking.
https://en.wikipedia.org/wiki?curid=46446
207,404
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Priority for construction was accorded to facilities in the 300 and 100 areas, as they would be required first, and there was insufficient skilled labor to work on all the areas simultaneously. Little work was done on the 200 areas until January 1944. Although construction commenced on 26 June 1943, the work at 200-W was only three percent complete by the end of the year. The construction of the separation building, 221-T, was also affected by delays in delivery of critical equipment such as stainless steel pipe and the 10-ton crane. There were also some late design changes. The pace picked up in mid-1944, and 100-W was completed in December. Ground was broken in the 100-E area on 2 August 1943, but work was only six percent complete at the end of April 1944. It was completed in February 1945. Ground was broken at 200-N on 17 November 1943, and was completed in November 1944. T plant began processing irradiated slugs on 26 December 1944; B Plant followed on 13 April 1945. U plant never did, and was used as a training facility.
https://en.wikipedia.org/wiki?curid=72002318
1,589,489
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Noise regulations in the United States and high fuel consumption led to the development of the 731 JetStar, a modification program which added new Garrett TFE731 turbofan engines with a number of detail changes. It has redesigned larger external fuel tanks that sit with their upper surfaces flush with the wing, rather than being centered on it. The cockpit area has a somewhat more "modern" looking nose and window arrangement. The 731 JetStar modification program was so successful that Lockheed produced 40 new JetStars, designated the JetStar II, from 1976 to 1979. The JetStar IIs were factory-new aircraft with the turbofan engines and revised external fuel tanks. Both 731 JetStars and JetStar IIs have greatly increased range, reduced noise, and better runway performance compared to the original JetStars.
https://en.wikipedia.org/wiki?curid=1070331
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This species is often used as a floating freshwater plant in both coldwater and tropical aquaria. Though without roots, it may attach itself to the substrate or objects in the aquarium. Its fluffy, filamentous, bright-green leaves provide excellent cover for newly hatched fish. It is propagated by cuttings. It is frequently used as a model organism for studies of plant physiology. One of the reasons for this is that it allows studies on shoot effects without influence of a root, which often makes interpretation of nutrition and toxicity experiments difficult in terrestrial plants. As it is free floating and therefore does not require a solid substrate, it has been used successfully in the biological life support systems "Aquarack/CEBAS" and "Omegahab" on space flights Hornwort plants or the epiphytes they support have been shown to degrade the herbicide atrazine.
https://en.wikipedia.org/wiki?curid=13157907
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Alumni in international politics and government include the current King of Tonga Tupou VI (Development Studies, 1980) who also served as Prime Minister from 2000 to 2006 and Foreign Minister from 1998 to 2004; Governor General of Grenada Sir Carlyle Glean (Education, 1982); Governor of Gibraltar Sir Robert Fulton (Social Sciences, 1970) who was formerly Commandant General Royal Marines; Kiribati Vice President Teima Onorio (Education, 1990); Turkish Deputy Prime Minister Murat Karayalçın (Development Economics, 1977) who also served as Foreign Minister; Finance Ministers of Australia (Mathias Cormann), South Africa (Tito Mboweni), Rwanda (Donald Kaberuka, later President of the African Development Bank), Thailand (Suchart Thada-Thamrongvech), and Venezuela (Pedro Rosas Bravo); Foreign Ministers of Iceland (Össur Skarphéðinsson) and The Gambia (Ousman Jammeh); Defence Minister of The Maldives Adam Shareef; current Lieutenant Governor of Delhi Anil Baijal and Democratic Republic of the Congo Budget Minister Aimé Boji; and former Cabinet Ministers of Cyprus (Marios Demetriades), Peru (Gino Costa), South Sudan (Agnes Kwaje Lasuba), Kenya (Hassan Wario), Egypt (Gamal El-Araby), Tanzania (Juma Ngasongwa), Rwanda (Daphrose Gahakwa), Ethiopia (Sinknesh Ejigu and Junedin Sado), Seychelles (Rolph Payet and Peter Sinon), Turkey (Cüneyd Düzyol), Brunei (Suyoi bin Osman and Adanan Yusof) and Yemen (Yahya Al-Mutawakel).
https://en.wikipedia.org/wiki?curid=197027
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If viral encephalitis is suspected, then questions can be asked about the individual's history and physical examination can be performed. Important aspects of one's history include immune status, exposure to animals, including insects, travel history, vaccination history, geography, and time of year. Symptoms usually occur acutely, and the most common symptoms of infection are fever, headache, altered mental status, sensitivity to light, stiff neck and back, vomiting, confusion, and, in severe cases, seizures, paralysis, and coma. Neuropsychiatric features such as behavioral changes, hallucinations, or cognitive decline are frequent. Severe symptoms are most common among infants and the elderly. Most infections are asymptomatic, lacking symptoms, whereas most symptomatic cases are mild illnesses.
https://en.wikipedia.org/wiki?curid=3169045
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The study of the principles of the universe has a long history and largely derives from direct observation and experimentation. The formulation of theories about the governing laws of the universe has been central to the study of physics from very early on, with philosophy gradually yielding to systematic, quantitative experimental testing and observation as the source of verification. Key historical developments in physics include Isaac Newton's theory of universal gravitation and classical mechanics, an understanding of electricity and its relation to magnetism, Einstein's theories of special and general relativity, the development of thermodynamics, and the quantum mechanical model of atomic and subatomic physics.
https://en.wikipedia.org/wiki?curid=38890
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Research by Imperial College London has shown that solar panel efficiency is improved by studding the light-receiving semiconductor surface with aluminum nanocylinders, similar to the ridges on Lego blocks. The scattered light then travels along a longer path in the semiconductor, absorbing more photons to be converted into current. Although these nanocylinders have been used previously (aluminum was preceded by gold and silver), the light scattering occurred in the near-infrared region and visible light was absorbed strongly. Aluminum was found to have absorbed the ultraviolet part of the spectrum, while the visible and near-infrared parts of the spectrum were found to be scattered by the aluminum surface. This, the research argued, could bring down the cost significantly and improve the efficiency as aluminum is more abundant and less costly than gold and silver. The research also noted that the increase in current makes thinner film solar panels technically feasible without "compromising power conversion efficiencies, thus reducing material consumption".
https://en.wikipedia.org/wiki?curid=3507365
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A giant change took place in 1978 when the world's was constructed. It pioneered many technologies used in modern wind turbines and allowed Vestas, Siemens and others to get the parts they needed. Especially important was the novel wing construction using help from German aeronautics specialists. The power plant was capable of delivering 2MW, had a tubular tower, pitch controlled wings and three blades. It was built by the teachers and students of the Tvind school. Before completion these "amateurs" were much ridiculed. The turbine still runs today and looks almost identical to the newest most modern mills.
https://en.wikipedia.org/wiki?curid=8312093
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Utilities across Canada are making large investments in the maintenance of ageing infrastructure and in the construction of new power lines and substations to connect new generation sources to the bulk power system. For instance, in 2009 Ontario spent $2.3 billion on a series of transmission projects aimed at connecting new renewable capacity fostered by the Green Energy Act. In Alberta, the AESO recommended in 2008 the construction of a $1.83 billion, 240 kV looped system in the southern part of the province to integrate up to 2,700 MW of new wind generation. In Quebec, Hydro-Québec TransÉnergie filed a $1.47 billion investment plan to connect 2,000 MW of new wind generation scheduled to come on-stream between 2011 and 2015.
https://en.wikipedia.org/wiki?curid=2082992
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Developed to increase the effective range of soldiers in the designated marksman role, the U.S. Navy developed the Mark 12 Special Purpose Rifle (SPR). Configurations in service vary, but the core of the Mark 12 SPR is an 18" heavy barrel with muzzle brake and free float tube. This tube relieves pressure on the barrel caused by standard handguards and greatly increases the potential accuracy of the system. Also common are higher magnification optics ranging from the 6× power Trijicon ACOG to the Leupold Mark 4 Tactical rifle scopes. Firing Mark 262 Mod 0 ammunition with a 77gr Open tip Match bullet, the system has an official effective range of 600+ meters. However published reports of confirmed kills beyond 800 m from Iraq and Afghanistan were not uncommon.
https://en.wikipedia.org/wiki?curid=19901
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Gaitskell's Labour party ceased supporting an independent deterrent in 1960 via its new "Policy for Peace", after the cancellation of Blue Streak made nuclear independence less likely. Labour also adopted a resolution favouring unilateral disarmament. Although Gaitskell opposed the resolution and it was reversed in 1961 in favour of continuing support of a general Western nuclear deterrent, the party's opposition to a British deterrent remained and became more prominent. This became a campaign issue during the 1964 general election. Alec Douglas-Home's incumbent Conservatives stated that the British independent deterrent was necessary for independence from the Americans and maintaining British world influence, and that it was "working for peace" in such cases as the passage of the Nuclear Test Ban Treaty. Led by Gaitskell's successor Harold Wilson, Labour emphasized domestic economic issues and decried the "Tory Nuclear Pretense" as neither independent nor a deterrent. The populace's greater interest in domestic over foreign policy likely contributed more to Labour's victory.
https://en.wikipedia.org/wiki?curid=2095669
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Both amphetamine and methamphetamine are used recreationally as euphoriants and aphrodisiacs, with methamphetamine being the more common recreational drug due to precursor availability and relative ease to manufacture. According to a National Geographic TV documentary on methamphetamine, "an entire subculture known as party and play is based around methamphetamine use." Members of this San Francisco subculture, which consists almost entirely of homosexual male methamphetamine users, will typically meet up through internet dating sites and have sex. Due to its strong stimulant and aphrodisiac effects and inhibitory effect on ejaculation, with repeated use, these sexual encounters will sometimes occur continuously for several days. The crash following the use of methamphetamine in this manner is very often severe, with marked hypersomnia.
https://en.wikipedia.org/wiki?curid=40542151
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After an equivalent of approximately 280 trips down the 4 km length to the far mirrors and back again, the two separate beams leave the arms and recombine at the beam splitter. The beams returning from two arms are kept out of phase so that when the arms are both in coherence and interference (as when there is no gravitational wave passing through), their light waves subtract, and no light should arrive at the photodiode. When a gravitational wave passes through the interferometer, the distances along the arms of the interferometer are shortened and lengthened, causing the beams to become slightly less out of phase. This results in the beams coming in phase, creating a resonance, hence, some light arrives at the photodiode, indicating a signal. Light that does not contain a signal is returned to the interferometer using a power recycling mirror, thus increasing the power of the light in the arms. In actual operation, noise sources can cause movement in the optics which produces similar effects to real gravitational wave signals; a great deal of the art and complexity in the instrument is in finding ways to reduce these spurious motions of the mirrors. Observers compare signals from both sites to reduce the effects of noise.
https://en.wikipedia.org/wiki?curid=81610
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The transport layer transfers data between source and destination processes. Generally, two connection modes are recognized, connection-oriented or connectionless. Connection-oriented service establishes a dedicated virtual circuit and offers various grades of guaranteed delivery, ensuring that data received is identical to data transmitted. Connectionless mode provides only best-effort service without the built-in ability to correct errors, which includes complete loss of data without notifying the data source of the failure. No logical connection, and no persistent state of the transaction exists between the endpoints, lending the connectionless mode low overhead and potentially better real-time performance for timing-critical applications such as voice and video transmissions.
https://en.wikipedia.org/wiki?curid=1117711
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The Institute of Optics and Electronics of the Chinese Academy of Sciences () is a Chinese science research institute located in the town of Wenxing, Shuangliu District of Chengdu, in southwest China's Sichuan province. It is the largest institute of Chinese Academy of Sciences (CAS) in southwest China, founded in 1970. It is a diversified organization with operations in photoelectric tracking measurement, beam control, adaptive optics, astronomical target photoelectric observation and recognition, advanced optical manufacturing, aerospace photoelectric equipment, micro nano optics, microelectronics optics, and biomedical optics. It has more than 1,200 staff, including 2 academicians of the Chinese Academy of Engineering (CAE), 1 winner of National Science Fund for Outstanding Young Scholars, 1 recruitment program of global experts, 1 chief scientist of National 973 Program, 8 state-level experts in the field of opto-electronics, 13 academic and technological research leaders in Sichuan, and 350 senior S&T personnel.
https://en.wikipedia.org/wiki?curid=62944559
2,100,255
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The first example of electronic countermeasures being applied in a combat situation took place during the Russo-Japanese war. On July 13, 1904, Russian wireless telegraphy stations installed in the Port Arthur fortress and on board Russian light cruisers successfully interrupted wireless communication between a group of Japanese battleships. The spark-gap transmitters in the Russian stations generated senseless noise while the Japanese were making attempts to coordinate their efforts in the bombing of a Russian naval base. Germany and United Kingdom interfered with enemy communications along the western front during World War I while the Royal Navy tried to intercept German naval radio transmissions. There were also efforts at sending false radio signals, having shore stations send transmissions using ships' call signs, and jamming enemy radio signals.
https://en.wikipedia.org/wiki?curid=879940
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GMC's Early Commissioning Program (ECP) is designed to enable students to become a second lieutenant in the US Army after the first two years in college. GMC offers funding specifically to help pay costs for Corps of Cadet members on the Milledgeville campus. The State Service Scholarship Program provides 39 full scholarships to qualified Georgia residents with an interest in military service as well as a quality college education. The program is funded through the Georgia General Assembly. Scholarship recipients are required to become members of either the Army or Air National Guard, and must be nominated by a member of the Georgia General Assembly. These scholarships cover tuition, fees, rooms, board, books and supplies. Scholarship winners must join the Corps of Cadets and participate in Army ROTC. Army ROTC scholarships are also available for qualified cadets interested in the Early Commissioning Program (ECP). These scholarships are funded through ROTC and cover tuition, fees, and books, plus a monthly stipend. There are various options for ROTC scholarship based on the student's desire for active duty or reserve component duty.
https://en.wikipedia.org/wiki?curid=3577797
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Computational science applies computing power to simulate real-world situations, enabling a better understanding of scientific problems than formal mathematics alone can achieve. The use of machine learning and artificial intelligence is becoming a central feature of computational contributions to science for example in agent-based computational economics, random forests, topic modeling and various forms of prediction. However, machines alone rarely advance knowledge as they require human guidance and capacity to reason; and they can introduce bias against certain social groups or sometimes underperform against humans.
https://en.wikipedia.org/wiki?curid=26700
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According to an international team of interdisciplinary scientists in a 2020 study, broad-base adoption of mass timber and their substitution for steel and concrete in new mid-rise construction projects over the next few decades has the potential to turn timber buildings into a global carbon sink, as they store the carbon dioxide taken up from the air by trees that are harvested and used as mass timber. Noting the demographic need for new urban construction for the next thirty years, the team analyzed four scenarios for the transition to mass-timber new mid-rise construction. Assuming business as usual, only 0.5% of new buildings worldwide would be constructed with timber by 2050 (scenario 1). This could be driven up to 10% (scenario 2) or 50% (scenario 3), assuming mass timber manufacturing would increase as a material revolution replacing cement and steel in urban construction by wood scales up accordingly. Lastly, if countries with current low industrialization level, e.g., Africa, Oceania, and parts of Asia, would also make the transition to timber (including bamboo), then even 90% timber by 2050 (scenario 4) is conceivable. This could result in storing between 10 million tons of carbon per year in the lowest scenario and close to 700 million tons in the highest scenario. The study found that this potential could be realized under two conditions. First, the harvested forests would need to be sustainably managed, governed, and used. Second, wood from demolished timber buildings would need to be reused or preserved on land in various forms.
https://en.wikipedia.org/wiki?curid=5980
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The primary characteristics of an HDD are its capacity and performance. Capacity is specified in unit prefixes corresponding to powers of : a 1-terabyte (TB) drive has a capacity of gigabytes (GB; where 1 gigabyte = (10) bytes). Typically, some of an HDD's capacity is unavailable to the user because it is used by the file system and the computer operating system, and possibly inbuilt redundancy for error correction and recovery. There can be confusion regarding storage capacity, since capacities are stated in decimal gigabytes (powers of 1000) by HDD manufacturers, whereas the most commonly used operating systems report capacities in powers of 1024, which results in a smaller number than advertised. Performance is specified as the time required to move the heads to a track or cylinder (average access time), the time it takes for the desired sector to move under the head (average latency, which is a function of the physical rotational speed in revolutions per minute), and finally the speed at which the data is transmitted (data rate).
https://en.wikipedia.org/wiki?curid=13777
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Green chemistry is the design of chemical products and processes that reduce or eliminate the use and generation of hazardous substances. Green chemistry is based upon twelve principles, identified in “Green Chemistry: Theory and Practice” and adopted by the US Environmental Protection Agency (EPA). It is an innovative technology which encourages the design of safer chemicals and products and minimizes the impact of wastes through increased energy efficiency, the design of chemical products that degrade after use and the use of renewable resources (instead of non-renewable fossil fuel such as petroleum, gas and coal). The Office of Pollution Prevention and Toxics (OPPT), created under the United States Pollution Prevention Act of 1990, promotes the use of chemistry for pollution prevention through voluntary, non-regulatory ' partnerships with academia, industry, other government agencies, and non-governmental organizations. The United States Environmental Protection Agency (EPA) promotes green chemistry as overseen by the OPPT. The California Green Chemistry Initiative moves beyond voluntary partnerships and voluntary information disclosure to require industry reporting and public disclosure.
https://en.wikipedia.org/wiki?curid=31677000
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The Consolidated B-24 Liberator and later version of the Fortress carried even more extensive defensive armament fitted into Sperry ball turrets. This was a superb defensive weapon that rotated a full 360 degrees horizontally with a 90-degree elevation. Its twin M2 Browning machine guns had an effective range of . The Liberator was the result of a proposal to assemble Fortresses in Consolidated plants, with the company returning with its own design of a longer-range, faster and higher-flying aircraft that could carry an extra ton of bombs. Early orders were for France (delivered to the RAF after the fall of France) and Britain, already at war, with just a batch of 36 for the USAAF.
https://en.wikipedia.org/wiki?curid=343960
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The 2015–16 Georgia Tech Yellow Jackets men's basketball team represented the Georgia Institute of Technology during the 2015–16 NCAA Division I men's basketball season. They were led by fifth year head coach Brian Gregory and played their home games at McCamish Pavilion. They were members of the Atlantic Coast Conference. The Yellow Jackets finished the season 21–15, 8–10 in ACC play to finish in a tie for 11th place. They defeated Clemson in the second round of the ACC tournament to advance to the quarterfinals where they lost to Virginia. They received an invitation to the National Invitation Tournament where they defeated Houston and South Carolina to advance to the quarterfinals where they lost to San Diego State.
https://en.wikipedia.org/wiki?curid=47257107
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The primary objective of the Master of Engineering Management is to interweave the business and technology curriculum together so that students of this program can learn to leverage both domains when making data-driven decisions that would impact the business comprehensively. While MBA and MEM programs share some similarities in shaping capable leaders through a core curriculum in economics, marketing, and operations, students with MEM degrees are a better fit for today’s technology companies simply because an undergraduate degree in a STEM field is a prerequisite for admission. Since it’s not a prerequisite for an MBA, a majority of candidates graduate with a non-technical education. In a world where technology touches almost all aspects of life and business, students with a MEM degree fit seamlessly into today’s high-tech companies that need tech-savvy leaders for data-driven decision making and innovation-driven global strategy and growth.
https://en.wikipedia.org/wiki?curid=14166774
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Another PDMS 3D microfluidic heart-on-a-chip design is measured to generate 10% to 15% of uniaxial cyclic mechanical strains. The device consists of a cell culture with hanging posts for caging and an actuation compartment with scaffolding posts to avoid buckling of PDMS, along with the cardiac cycle pressure signal imitation. The neonatal rat micro-engineered cardiac tissues (μECTs) stimulated by this design show improved synchronous beating, proliferation, maturation, and viability compared to the unstimulated control. The contraction rate of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) is observed to accelerate with 100-fold less isoprenaline, a heart block treatment, when having electrical pacing signal (+ES) compared to that without ES.
https://en.wikipedia.org/wiki?curid=33980770
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Closure of Ignalina faced fierce opposition from Lithuanians, as it provided income to most local residents. To compensate for this, a project was started to encourage tourism and other small businesses. Others were afraid that the price of electricity would skyrocket or that Lithuania would be left to cope with the extremely high costs of decommissioning the plant and disposing of its nuclear waste. A 2008 referendum proposed extending the operation of Unit 2 until a new plant could be completed as a replacement; the referendum gained 1,155,192 votes for the proposal, but ultimately failed to gain the 50% turnout necessary to be passed. President Valdas Adamkus opposed the measure on grounds that continued operation would not respect Lithuania's international commitments.
https://en.wikipedia.org/wiki?curid=1407330
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Ganymede's surface has an albedo of about 43 percent. Water ice seems to be ubiquitous on its surface, with a mass fraction of 50–90 percent, significantly more than in Ganymede as a whole. Near-infrared spectroscopy has revealed the presence of strong water ice absorption bands at wavelengths of 1.04, 1.25, 1.5, 2.0 and 3.0 μm. The grooved terrain is brighter and has a more icy composition than the dark terrain. The analysis of high-resolution, near-infrared and UV spectra obtained by the "Galileo" spacecraft and from Earth observations has revealed various non-water materials: carbon dioxide, sulfur dioxide and, possibly, cyanogen, hydrogen sulfate and various organic compounds. "Galileo" results have also shown magnesium sulfate (MgSO) and, possibly, sodium sulfate (NaSO) on Ganymede's surface. These salts may originate from the subsurface ocean.
https://en.wikipedia.org/wiki?curid=54211
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In Australia, "C. fleckeri" has caused at least 64 deaths since the first report in 1883, but most encounters appear to result only in mild envenomation. Among 225 analyzed "C. fleckeri" stings in Australia's Top End from 1991 to 2004, only 8% required hospital admission, 5% received antivenom and there was a single fatality (a 3-year-old child). 26% experienced severe pain, while it was moderate to none in the remaining. Most deaths in recent decades have been children, as their smaller body mass puts them at a higher risk of fatal envenomation. When people do die, it is usually caused by a cardiac arrest occurring within minutes of the sting. It takes approximately 3 m (10 ft) of tentacle to deliver the fatal dose.
https://en.wikipedia.org/wiki?curid=1881635
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In March 2018 the collaboration published a paper in "Nature" announcing the discovery of a broad absorption profile centered at a frequency of formula_1MHz in the sky-averaged signal after subtracting Galactic synchrotron emission. The absorption profile has a width of formula_2MHz and an amplitude of formula_3K, against a background RMS of 0.025K, giving it a signal-to-noise ratio of 37. The equivalent redshift is centered at formula_4, spanning z=20–15. The signal is possibly due to ultraviolet light from the first stars in the Universe altering the emission of the 21cm line by lowering the temperature of the hydrogen relative to the cosmic microwave background (the mechanism is Wouthuysen–Field coupling). A "more exotic scenario," encouraged by the unexpected strength of the absorption, is that the signal is due to interactions between dark matter and baryons.
https://en.wikipedia.org/wiki?curid=56733354
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The First World War saw a decline of economic production, with a major reallocation to munitions. It forced Britain to use up its financial reserves and borrow large sums from the U.S. Because of its prime importance in international finance, the entry of the UK into the war in August 1914 threatened a possible worldwide liquidity crisis. In Britain itself, there were fears of a run on the banks, which prompted the Treasury to take inflationary measures and begin printing 5 million new banknotes a day. To assuage nervous markets, a one-month moratorium on payments was declared, while the Bank of England agreed to guarantee the City of London's bills of exchange and to act as underwriter for London's Clearing houses.
https://en.wikipedia.org/wiki?curid=33643110
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Written during the last productive decade of Mary Shelley's career, her contributions fill about three-quarters of these five volumes and reveal her to be a professional woman of letters. They demonstrate her knowledge of several languages and historical research covering several centuries, her ability to tell a gripping biographical narrative, and her interest in the burgeoning field of feminist historiography. She "wrote with many books to hand – reading (or rereading) some, consulting others, cross-referring, interweaving abridged and paraphrased source material with her own comment". Shelley combined secondary sources with memoir and anecdote and included her own judgments, a biographical style made popular by the 18th-century critic Samuel Johnson in his "Lives of the Poets" (1779–81). She describes this technique in her "Life of Metastasio":
https://en.wikipedia.org/wiki?curid=17481711
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In February 2017, the University of New England announced that it would no longer manage the Old Teachers' College on the basis that it no longer used the site and was costing the university around $500,000 a year. The NSW Department of Industry – Lands took over responsibility until a suitable manager could be found. UNE's decision was criticised by local MP Adam Marshall, with the state government having not been informed in advance of the move. Existing tenants, including the New England Conservatorium of Music, were able to continue in the building. The Department approached the Armidale Regional Council to take over management of the site, but the council refused on the basis that the costs of repairs and maintenance would be too high. The council administrators had earlier suggested that if UNE had informed them six months earlier, they may have been able to relocate the local library there. The Armidale School also refused to take over as manager.
https://en.wikipedia.org/wiki?curid=57539511
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Following word of its debut, interest in the machine grew across Europe. Kempelen, however, was more interested in his other projects and avoided exhibiting the Turk, often lying about the machine's repair status to prospective challengers. Von Windisch wrote at one point that Kempelen "refused the entreaties of his friends, and a crowd of curious persons from all countries, the satisfaction of seeing this far-famed machine". In the decade following its debut at Schönbrunn Palace the Turk only played one opponent, Sir Robert Murray Keith, a Scottish noble, and Kempelen went as far as dismantling the Turk entirely following the match. Kempelen was quoted as referring to the invention as a "mere bagatelle", as he was not pleased with its popularity and would rather continue work on steam engines and machines that replicated human speech.
https://en.wikipedia.org/wiki?curid=418820
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Lipophilicity of the statins is considered to be quite important since the hepatoselectivity of the statins is related to their lipophilicity. The more lipophilic statins tend to achieve higher levels of exposure in non-hepatic tissues, while the hydrophilic statins tend to be more hepatoselective. The difference in selectivity is because lipophilic statins passively and non-selectively diffuse into both hepatocyte and non-heptatocyte, while the hydrophilic statins rely largely on active transport into hepatocyte to exert their effects. High hepatoselectivity is thought to translate into reduced risk of adverse effects. It has been reported that the organic anion transporting polypeptide (OATP) is important for the hepatic uptake of hydrophilic statins such as rosuvastatin and pravastatin. OATP-C is expressed in liver tissue on the basolateral membrane of hepatocytes and is considered to be a potential contributor for the low IC for rosuvastatin in hepatocytes. Of the marketed statins, cerivastatin was the most lipophilic and also had the largest percentage of serious adverse effects due to its ability to inhibit vascular smooth muscle proliferation and as a result was voluntarily removed from the market by the manufacturer.
https://en.wikipedia.org/wiki?curid=14142409
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But in addition to bombers, "Luftflotte 3" also organised a number of Focke-Wulf Fw 190s for bombing duty. These began to be used for daytime raids as fighter-bombers, or "Jabos". After a few attempts with some losses, the "Jabo" force also turned to the night role. Even at its economical cruising speed, the aircraft would prove essentially impossible for the early Beaufighters to catch. A series of raids in April went unchallenged, and the biggest threat to the attacker was landing accidents or becoming lost and landing at RAF bases, which happened on several occasions. Although the "Jabo" force was capable of causing little damage, the RAF responded by rapidly introducing new aircraft like the Beaufighter VI, and equipping them with the new radars as quickly as possible. However, these aircraft had little speed advantage over the FWs, and were inadequate to the task.
https://en.wikipedia.org/wiki?curid=43764346
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Since the first publication in 1916, there have been four additional revised editions of the Stanford–Binet Intelligence Scales, the first of which was developed by Lewis Terman. Over twenty years later, Maud Merrill was accepted into Stanford's education program shortly before Terman became the head of the psychology department. She completed both her master's degree and Ph.D. under Terman and quickly became a colleague of his as they started the revisions of the second edition together. There were 3,200 examinees, aged one and a half to eighteen years, ranging in different geographic regions as well as socioeconomic levels in attempts to comprise a broader normative sample (Roid & Barram, 2004). This edition incorporated more objectified scoring methods, while placing less emphasis on recall memory and including a greater range of nonverbal abilities (Roid & Barram, 2004) compared to the 1916 edition.
https://en.wikipedia.org/wiki?curid=239041
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1877 – Charles Cros invents the Paleophone. Paris was clearly the centre of the world in the early days of sound recording. It was there that Leon Scott de Martinville invented his Phonautograph to capture sound onto paper in 1857 and 20 years later Charles Cros took the process forward by working out how to record sound onto a cylinder by tracing oscillations using a screw. In April 1877 he wrote a paper describing his thesis and submitted it in a sealed envelope to the Academy of Science in Paris. Before he got a chance to build a prototype, a hard working inventor by the name of Thomas Edison living thousands of miles away in the USA beat him to it. Edison had been independently considering the same problem and in late 1877 he built a machine that recorded and played back sound which he called a Phonograph. Edison became world famous whilst Charles Cros is largely forgotten.
https://en.wikipedia.org/wiki?curid=2417230
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The Royal Italian Army during the Great War had employed, alongside the various models of grenade launchers and mortars, the innovative mortar ML 3 inch Stokes. In the early thirties the Kingdom of Italy bought the Brandt 81 mm Mle 1927 directly in France, derived from the Stokes, to equip the troops sent to Ethiopia. Trials concluded that the Brandt was so great a weapon that, in addition to having a significant commercial success, in a few years was built under license or copied in most of the major countries of the world. Even in Italy in fact the company Costruzioni Elettro-Meccaniche di Saronno, in addition to producing the Brandt license, created an improved version, the "Mortaio da 81 Mod. 35", which proved to be the best of the mortars of the Royal Italian Army.
https://en.wikipedia.org/wiki?curid=32453499
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An ischemic cascade occurs where an energetic molecular problem arises due to lack of oxygen and nutrients. The cascade results in decreased production of adenosine triphosphate (ATP), which is a high-energy molecule needed for cells in the brain to function. Consumption of ATP continues in spite of insufficient production, this causes total levels of ATP to decrease and lactate acidosis to become established (ionic homeostasis in neurons is lost). The downstream mechanisms of the ischemic cascade thus begins. Ion pumps no longer transport Ca out of cell, this triggers release of glutamate, which in turn allows calcium into cell walls. In the end the apoptosis pathway is initiated and cell death occurs.
https://en.wikipedia.org/wiki?curid=249924
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On 11 July 1969, just before the successful Moon landing of Apollo 11, a request for proposal for the final development and building the Apollo LRV was released by Marshall. Boeing, Bendix, Grumman, and Chrysler submitted proposals. Following three months of proposal evaluation and negotiations, Boeing was selected as the Apollo LRV prime contractor on 28 October 1969. Boeing would manage the LRV project under Henry Kudish in Huntsville, Alabama. Kudish was replaced the following year in 1970 by LRV Project Manager Earl Houtz. As a major subcontractor, the General Motors' Defense Research Laboratories in Santa Barbara, California, would furnish the mobility system (wheels, motors, and suspension); this effort would be led by GM Program Manager Samuel Romano andFerenc Pavlics. Boeing in Seattle, Washington, would furnish the electronics and navigation system. Vehicle testing would take place at the Boeing facility in Kent, Washington, and the chassis manufacturing and overall assembly would be at the Boeing facility in Huntsville.
https://en.wikipedia.org/wiki?curid=18238
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In 1955, the Technical College received a large gift of land. Local Architect, property developer and entrepreneur Tom Scott Sutherland, purchased the Victorian manor and estate of Garthdee House in 1953 on the outskirts of the city. Finding himself and his wife living out of only four rooms in the enormous mansion, he donated it and the estate in 1955 for a new school of architecture. These classes had taken place at Gray's School of Art, but had been expanding in the 1940s and 1950s and much more space was needed. Following completion of a modern extension to the house, the new Scott Sutherland School of Architecture opened in 1957. In 1966, Gray's School of Art also moved to a large new building on this estate, freeing its Schoolhill building for administrative use. By 2013, all activities had transferred to Garthdee, with the addition of land immediately adjacent purchased from Aberdeen City Council in the 1990s.
https://en.wikipedia.org/wiki?curid=381864
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