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The hallmark of optogenetics therefore is introduction of fast light-activated channels, pumps, and enzymes that allow temporally precise manipulation of electrical and biochemical events while maintaining cell-type resolution through the use of specific targeting mechanisms. Among the microbial opsins which can be used to investigate the function of neural systems are the channelrhodopsins (ChR2, ChR1, VChR1, and SFOs) to excite neurons and anion-conducting channelrhodopsins for light-induced inhibition. Indirectly light-controlled potassium channels have recently been engineered to prevent action potential generation in neurons during blue light illumination. Light-driven ion pumps are also used to inhibit neuronal activity, e.g. halorhodopsin (NpHR), enhanced halorhodopsins (eNpHR2.0 and eNpHR3.0, see Figure 2), archaerhodopsin (Arch), fungal opsins (Mac) and enhanced bacteriorhodopsin (eBR).
https://en.wikipedia.org/wiki?curid=14958673
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Gene patents confer a property right to the patent holder. While CIPO will grant patents for isolated gDNA and cDNA, the Supreme Court of Canada has not yet ruled on gene patentability. However, in 2016 the Children’s Hospital of Eastern Ontario (CHEO) sought to invalidate five Canadian patents held by Transgenomic. The gene patents covered the genes associated with, and genetic testing for Long QT syndrome. The parties reached a settlement. The patent was not invalidated, but, Transgenomic provided Canadian health institutions the right to test Canadians for the disease on a non-profit basis. In "Association for" "Molecular Pathology v Myriad", the United States Supreme Court determined that genes were unpatentable products of nature and that no intellectual property existed as nothing was invented. Given this decision, the majority of Canadian Long QT syndrome tests were previously outsourced to the United States. After the settlement, domestic testing levels increased in Canada. The terms of the settlement could set a precedent for the repatriation of further genetic testing.
https://en.wikipedia.org/wiki?curid=39666891
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Honda's supreme year in its days as an engine supplier came with McLaren in 1988. Mated to the Steve Nichols designed McLaren MP4/4 and with then dual World Champion Alain Prost and Brazilian Ayrton Senna as the drivers, the McLaren-Honda duo had an almost perfect season. Unlike most, Honda built an all-new V6 turbo (the RA168E) for the year to cope with the reduced fuel limit (150 liters) and turbo boost limit (2.5 BAR, down from 4.0 BAR in 1987) and it paid massive dividends. McLaren-Honda claimed 15 pole positions in the 16 races, 13 of them for Senna, and also claimed 15 race wins, 8 from Senna (a new season record) and 7 from Prost which actually equaled the old record he jointly held with Jim Clark. McLaren-Honda scored a then-record 199 points in the Constructors' Championship, a massive 134 points ahead of second-placed Ferrari (whose driver Gerhard Berger was the only non-Honda-powered pole winner in Britain and the only non-Honda-powered winner in Italy), while Senna and Prost were the only drivers in contention for the Drivers' Championship ultimately won by Senna. Prost actually scored more points than Senna over the course of the season, largely thanks to 7-second-place finishes to go with his 7 wins, but under the rules of the time, only the best 11 scores counted to the championship which saw the title go to the Brazilian.
https://en.wikipedia.org/wiki?curid=69053418
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When swimming, otariids rely on their fore-flippers for locomotion in a wing-like manner similar to penguins and sea turtles. Fore-flipper movement is not continuous, and the animal glides between each stroke. Compared to terrestrial carnivorans, the fore-limbs of otariids are reduced in length, which gives the locomotor muscles at the shoulder and elbow joints greater mechanical advantage; the hind-flippers serve as stabilizers. Phocids and walruses swim by moving their hind-flippers and lower body from side to side, while their fore-flippers are mainly used for steering. Some species leap out of the water, which may allow them to travel faster. In addition, sea lions are known to "ride" waves, which probably helps them decrease their energy usage.
https://en.wikipedia.org/wiki?curid=60261
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Most of the proteins and glycoproteins that constitute the complement system are synthesized by hepatocytes. But significant amounts are also produced by tissue macrophages, blood monocytes, and epithelial cells of the genitourinary system and gastrointestinal tract. The three pathways of activation all generate homologous variants of the protease C3-convertase. The classical complement pathway typically requires antigen-antibody complexes for activation (specific immune response), whereas the alternative pathway can be activated by spontaneous complement component 3 (C3) hydrolysis, foreign material, pathogens, or damaged cells. The mannose-binding lectin pathway can be activated by C3 hydrolysis or antigens without the presence of antibodies (non-specific immune response). In all three pathways, C3-convertase cleaves and activates component C3, creating C3a and C3b, and causes a cascade of further cleavage and activation events. C3b binds to the surface of pathogens, leading to greater internalization by phagocytic cells by opsonization.
https://en.wikipedia.org/wiki?curid=543131
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A "pintle mount" is a swiveling mount that allows the gun to be freely traversed or elevated, while the base of the mount is still fixed keeping the whole system in one stable position: typically the mounting is either a rod on the underside of the gun (a pintle rod) that mates with a socket mechanism, or an intermediary cradle that mounts to the sides of the weapon's barrel or receiver. Due to the stability offered by the mount, the gun typically does not need a shoulder stock, with many modern examples using two-handed spade grips. It is most commonly found on armoured vehicles, improvised fighting vehicles such as technicals, side gun stations on WW2 and earlier-era bomber aircraft, and the door guns of armed transport helicopters. Early single-shot examples referred to as "swivel guns" were commonly mounted on the deck rails of naval vessels in the Age of Sail to deter boarders at close range.
https://en.wikipedia.org/wiki?curid=24019952
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The NRDL testing and decontamination activities caused significant contamination of the shipyard site. The NRDL and the military radiation training school at nearby Naval Station Treasure Island loaded the nuclear waste left from experiments into steel barrels and sent weekly barges to dump them offshore near the Gulf of the Farallons, which is a US National Wildlife Refuge and a major commercial fishery. Between 1946 and 1970, records estimate the lab and naval station dumped an estimated 47,000 drums of nuclear waste in the Pacific Ocean 30 miles west of San Francisco, creating the first and largest offshore nuclear waste dump in the United States. The USGS states the barrels contain only "low-level radioactive waste," but this is disputed by historical records and experts.
https://en.wikipedia.org/wiki?curid=50830846
1,975,389
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Healthcare training programs have adopted virtual reality simulation (VRS) as a training tool for nursing students. This computer-based three-dimensional simulation tool allows for nursing students to practice various nursing skills repeatedly in a risk-free environment. A nursing program at a major Midwestern state university agreed to utilize a VRS module for teaching the insertion of an intravenous (IV) catheter, and complete an evaluation on the effectiveness of the program. The VRS composed of a computer program and a haptic arm device, which worked together to simulate the feel of vascular access. On the computer screen, the user would have to select the equipment for the procedure in the correct order. The user then palpates the veins of the haptic arm, and virtually inserts the IV catheter. The program provides immediate feedback by notifying the user when he/she misses a step and needs to restart the procedure.
https://en.wikipedia.org/wiki?curid=4627121
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Epidural administrations can also cause bleeding issues, including "bloody tap", which occurs in approximately 1 in 30–50 people. This occurs when epidural veins are inadvertently punctured with the needle during the insertion. It is a common occurrence and is not usually considered a problem in people who have normal blood clotting. Permanent neurological problems from bloody tap are extremely rare, estimated at less than 0.07% of occurrences. However, people who have a coagulopathy may have a risk of epidural hematoma, and those with thrombocytopenia might bleed more than expected. A 2018 Cochrane review found no evidence regarding the effect of platelet transfusions prior to a lumbar puncture or epidural anesthesia for participants that have thrombocytopenia. It is unclear whether major surgery-related bleeding within 24 hours and the surgery-related complications up to 7 days after the procedure are affected by epidural use.
https://en.wikipedia.org/wiki?curid=985885
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This resulted in commercial success for von Welsbach and his invention, and created great demand for thorium. Its production resulted in a large amount of lanthanides being simultaneously extracted as by-products. Applications were soon found for them, especially in the pyrophoric alloy known as "mischmetal" composed of 50% cerium, 25% lanthanum, and the remainder being the other lanthanides, that is used widely for lighter flints. Usually iron is added to form the alloy ferrocerium, also invented by von Welsbach. Due to the chemical similarities of the lanthanides, chemical separation is not usually required for their applications, such as the addition of mischmetal to steel as an inclusion modifier to improve mechanical properties, or as catalysts for the cracking of petroleum. This property of cerium saved the life of writer Primo Levi at the Auschwitz concentration camp, when he found a supply of ferrocerium alloy and bartered it for food.
https://en.wikipedia.org/wiki?curid=24580596
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Over two decades of research has revealed that the properties of a SNA conjugate are a synergistic combination of those of the core and the shell. The core serves two purposes: 1) it imparts upon the conjugate novel physical and chemical properties (e.g., plasmonic, catalytic, magnetic, luminescent), and 2) it acts as a scaffold for the assembly and orientation of the nucleic acids. The nucleic acid shell imparts chemical and biological recognition abilities that include a greater binding strength, cooperative melting behavior, higher stability, and enhanced cellular uptake without the use of transfection agents (compared to the same sequence of linear DNA). It has been shown that one can crosslink the DNA strands at their base, and subsequently dissolve the inorganic core with KCN or I to create a core-less (hollow) form of SNA (Fig. 3, right), which exhibits many of the same properties as the original polyvalent DNA gold nanoparticle conjugate (Fig. 3, left).
https://en.wikipedia.org/wiki?curid=36131613
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During 1967-72 Clayton resided half time in Cambridge U.K. at Hoyle's invitation to import and advise nucleosynthesis research at Hoyle's newly constructed Institute of Theoretical Astronomy. Clayton did this by bringing his graduate students at Rice with him to Cambridge. After Hoyle's abrupt 1972 resignation from Cambridge Hoyle made three research visits with Clayton at Rice University. After Clayton's 1989 move to Clemson University, his research with Bradley S. Meyer showed how the uniquely puzzling Ca isotope of calcium had become so abundant in the Galaxy owing to a relatively rare form of Type Ia supernovae in which the appropriate neutron-enriched quasiiequilibrium nucleosynthesis occurs. They subsequently explained why the minor Mo and Mo isotopes of the element molybdenum had become dominant in supernovae stardust explaining an experimental riddle in stardust isotopic abundances.
https://en.wikipedia.org/wiki?curid=36061850
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For example, for the disordered Ising chain discussed above, one can prepare random symmetry-broken initial states which are product states in the formula_11basis: formula_32. These randomly chosen states are at infinite temperature. Then, one can measures the local magnetization formula_33in time, which acts as an order parameter for symmetry breaking. It is straightforward to show that formula_34saturates to a non-zero value even for infinitely late times in the symmetry-broken spin-glass phase, while it decays to zero in the paramagnet. The singularity in the eigenspectrum properties at the transition between the localized SG and PM phases translates into a sharp dynamical phase transition which is measurable. Indeed, a nice example of this is furnished by recent experiments detecting time-crystals in Floquet MBL systems, where the time crystal phase spontaneously breaks both time translation symmetry and spatial Ising symmetry, showing correlated spatiotemporal eigenstate order.
https://en.wikipedia.org/wiki?curid=59188974
2,060,585
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Cael Norman Sanderson ( ; born June 20, 1979) is an American former folkstyle and freestyle wrestler who is the current head coach of Penn State University's wrestling team. As a wrestler, he won an Olympic Gold medal and was undefeated in four years of college wrestling at Iowa State University (ISU) (159–0), becoming a four-time NCAA Division I champion (1999–2002). He is the only wrestler in NCAA Division I history to go undefeated in official matches with more than 100 wins. "Sports Illustrated" named his college career as the second most impressive college sports feat of all-time, behind the setting of four world records by Jesse Owens in a single hour at the 1935 Big Ten track and field conference championship meet.
https://en.wikipedia.org/wiki?curid=637163
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Vegetius once wrote that "every plan... is to be considered, every expedient tried and every method taken before matters are brought to this last extremity [general engagements]... Good officers decline general engagements where the odds are too great, and prefer the employment of stratagem and finesse to destroy the enemy as much as possible... without exposing their own forces.". However, Vegetius was writing late in the fourth century AD, in the latter years of the Empire. During this period, and for much of the Empire, it can be argued that the Romans did follow a grand strategy calling for limited direct operational engagement. However, earlier in its history, in the Republic and early Empire Rome showed little reluctance to become engaged in direct military engagement, prosecuting offensive operations against numerous adversaries.
https://en.wikipedia.org/wiki?curid=8049650
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An ion-exchange resin such as chelex 100, which contains chelating ligands bound to a polymer, can be used in water softeners and in chromatographic separation techniques. In solvent extraction the formation of electrically-neutral complexes allows cations to be extracted into organic solvents. For example, in nuclear fuel reprocessing uranium(VI) and plutonium(VI) are extracted into kerosene as the complexes [MO(TBP)(NO)] (TBP = tri-"n"-butyl phosphate). In phase-transfer catalysis, a substance which is insoluble in an organic solvent can be made soluble by addition of a suitable ligand. For example, potassium permanganate oxidations can be achieved by adding a catalytic quantity of a crown ether and a small amount of organic solvent to the aqueous reaction mixture, so that the oxidation reaction occurs in the organic phase.
https://en.wikipedia.org/wiki?curid=20869108
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In the aftermath, Germany accelerated plans to close its nuclear power reactors and decided to phase the rest out by 2022 (see also Nuclear power in Germany). Belgium and Switzerland have also changed their nuclear policies to phase-out all nuclear energy operations. Italy held a national referendum, in which 94 percent voted against the government's plan to build new nuclear power plants. In France, President Hollande announced the intention of the government to reduce nuclear usage by one third. However, the government earmarked only one power station for closure – the aging Fessenheim Nuclear Power Plant on the German border – which prompted some to question the government's commitment to Hollande's promise. Industry Minister Arnaud Montebourg is on record as saying that Fessenheim will be the only nuclear power station to close. On a visit to China in December 2014 he reassured his audience that nuclear energy was a "sector of the future" and would continue to contribute "at least 50%" of France's electricity output. Another member of Hollande's Socialist Party, the MP Christian Bataille, said that Hollande announced the nuclear curb to secure the backing of his Green coalition partners in parliament.
https://en.wikipedia.org/wiki?curid=31162817
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In the United States, poverty and lack of documentation status puts migrant farmworkers in housing situations that make them far more likely to contract infectious or parasitic diseases and to suffer from chemical related ailments than the general U.S. population. Field workers who are exposed to pesticides continue to further expose their families in their residences, especially through contaminated clothing in which the residue settles as house dust. Increased rates of a full range of adverse birth outcomes result from high exposure to pesticides in a study of 500,000 births among farm workers in California's San Joaquin Valley.
https://en.wikipedia.org/wiki?curid=959629
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Behaviorism is a psychological movement that can be contrasted with philosophy of mind. The basic premise of behaviorism is that the study of behavior should be a natural science, such as chemistry or physics. Initially behaviorism rejected any reference to hypothetical inner states of organisms as causes for their behavior, but B.F. Skinner's radical behaviorism reintroduced reference to inner states and also advocated for the study of thoughts and feelings as behaviors subject to the same mechanisms as external behavior. Behaviorism takes a functional view of behavior. According to Edmund Fantino and colleagues: "Behavior analysis has much to offer the study of phenomena normally dominated by cognitive and social psychologists. We hope that successful application of behavioral theory and methodology will not only shed light on central problems in judgment and choice but will also generate greater appreciation of the behavioral approach."
https://en.wikipedia.org/wiki?curid=540801
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Another very select and infrequent use of military psychology is in the interview of subjects, the interrogation of prisoners, and the vetting of those who may provide information of operational or intelligence value that would enhance outcomes of friendly military operations or reduce friendly and enemy casualties. Psychology's scientific principles applied here allow the interviewer, agent, or interrogator to get as much information as possible through non-invasive means without the need to resort to active measures or risk violating the rules of engagement, host nation agreements, international and military law or crossing the threshold of the Geneva Conventions' guidelines to which the United States and its allies subscribe, regardless of the status of many of the modern belligerent countries on the international laws and United Nations agreements.
https://en.wikipedia.org/wiki?curid=15059413
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Ethnomethodology has often perplexed commentators, due to its radical approach to questions of theory and method. With regard to theory, Garfinkel has consistently advocated an attitude of ethnomethodological indifference, a principled agnosticism with regard to social theory which insists that the shared understandings of members of a social setting under study take precedence over any concepts which a social theorist might bring to the analysis from outside that setting. This can be perplexing to traditional social scientists, trained in the need for social theory. A multiplicity of theoretical references by Anne Rawls, in her introduction to "Ethnomethodology's Program", might be interpreted to suggest a softening of this position towards the end of Garfinkel's life. However, the position is consistent with ethnomethodology's understanding of the significance of "member's methods", and with certain lines of philosophical thought regarding the philosophy of science (Polanyi 1958; Kuhn 1970; Feyerabend 1975), and the study of the actual practices of scientific procedure. It also has a strong correspondence with the later philosophy of Ludwig Wittgenstein, especially as applied to social studies by Peter Winch.
https://en.wikipedia.org/wiki?curid=515580
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"H. laboriosa" is native to the eastern United States and are found in warm, humid conditions. They are often found nesting 33cm to 71cm in the ground, in moderately dry and sandy soils in eastern United States, ranging from Illinois to the New England states, south to Mississippi and Florida. They are solitary ground nesting bees, and they prefer soil that is covered by leaf litter with low moisture, so there would be a lack of roots near their nests to keep the soil relatively dry. Under these leaf litters are hidden burrows which connects to tunnels that can be 20cm long leading to their nests . If a nest has been invaded or disturbed by other organisms, often the bees will abandon it to find a new area nest. For example, it is common for ant species such as "Iridomyrmex humilis" to invade open nesting sites which results in nest abandonment. Another instance where "H. laboriosa" abandon their nests is when cleptoparasitic bees in the genus "Melecta" parasitizes these nests with their eggs. These parasitic bees are commonly referred to as Cuckoo bees; they parasitize other bee species by invading their nests to lay their parasitic eggs, so their offspring can thrive off the host's resources (pollen deposits) that are meant for the host's offspring. When "H. laboriosa" is searching for new areas for potential nesting sites, they prefer areas that have been dug already but uninhabited by other organisms. These nesting sites are usually near blueberry orchards with pits that have been previously plowed.
https://en.wikipedia.org/wiki?curid=5224409
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Although the "Bencao Tujing" was an important pharmaceutical work of the age, Su Song is perhaps better known for his work in horology. His book "Xinyi Xiangfayao" (新儀象法要; lit. 'Essentials of a New Method for Mechanizing the Rotation of an Armillary Sphere and a Celestial Globe') documented the intricate mechanics of his astronomical clock tower in Kaifeng. This included the use of an escapement mechanism and world's first known chain drive to power the rotating armillary sphere crowning the top as well as the 133 clock jack figurines positioned on a rotating wheel that sounded the hours by banging drums, clashing gongs, striking bells, and holding plaques with special announcements appearing from open-and-close shutter windows. While it had been Zhang Heng who applied the first motive power to the armillary sphere via hydraulics in 125 CE, it was Yi Xing (683–727) in 725 CE who first applied an escapement mechanism to a water-powered celestial globe and striking clock. The early Song dynasty horologist Zhang Sixun (fl. late 10th century) employed liquid mercury in his astronomical clock because there were complaints that water would freeze too easily in the clepsydra tanks during winter.
https://en.wikipedia.org/wiki?curid=9311753
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In 1937, Bell Laboratories in New York City gave a demonstration of two-channel stereophonic motion pictures, developed by Bell Labs and Electrical Research Products, Inc. Once again, conductor Leopold Stokowski was on hand to try out the new technology, recording onto a special proprietary nine-track sound system at the Academy of Music in Philadelphia, during the making of the movie "One Hundred Men and a Girl" for Universal Pictures in 1937, after which the tracks were mixed down to one for the final soundtrack. A year later, MGM started using three tracks instead of one to record the musical selections of movie soundtracks, and very quickly upgraded to four. One track was used for dialogue, two for music, and one for sound effects. The very first two-track recording MGM made (although released in mono) was "It Never Rains But What It Pours" by Judy Garland, recorded on June 21, 1938, for the movie "Love Finds Andy Hardy".
https://en.wikipedia.org/wiki?curid=1369770
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The NVO development project was distributed across many institutions and includes teams at the Johns Hopkins University, California Institute of Technology, Space Telescope Science Institute, NOAO, Infrared Processing and Analysis Center, San Diego Supercomputer Center, and the Associated Universities, Inc. Affiliate organizations with participating teams include Goddard Space Flight Center, Carnegie Mellon University, University of Pittsburgh, National Center for Supercomputing Applications, Smithsonian Astrophysical Observatory, University of Southern California, Fermilab, United States Naval Observatory, the University of Wisconsin–Madison, and National Radio Astronomy Observatory. The NVO, a US effort, had affiliates throughout the international astronomical community including IVOA, AstroGrid (UK), Euro-VO, the Japanese VO, the Australian VO, VO India and ten other national programs.
https://en.wikipedia.org/wiki?curid=5710546
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Other electrophysiological monitoring techniques such as evoked spinal cord potential (ESCP), somatosensory evoked potential (SEP) and SSEP (short-latency SEP) could be coupled with ECG, which then present excitatory ECG-triggered SSEP technique. The amplitude of the EP or evoked response is usually interpreted as the severity of the biological entities' response toward the applied electromagnetic field. Evoked potentials are merely acquired when the applied excitation is more than the excitation threshold of the biological entity. In such cases, excitatory input voltages are applied in different modes, by a stimulation rate of 0.1 to 100 Hz, current stimulation amplitudes of 0 to 200 mA and load resistance of 1 kΩ, which gives 0-200 mV amplitude (in case of constant resistance) and 40 mW electrical power. In some cases, stimulation module of ESCP, SEP, and SSEP techniques is similar to pulsed electromagnetic field (PEMF) generators.
https://en.wikipedia.org/wiki?curid=60902351
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In 1930 Allison returned to the University of Chicago, where he became a professor in 1942, and the Frank P. Hixon Distinguished Service Professor of Physics in 1959. He studied the Compton effect and the dynamical theory of x-ray diffraction. At the time x-rays were an important means of investigating atomic structures, but the concept that light had both wave and particle properties, as demonstrated by Arthur Compton, was not universally accepted. William Duane from Harvard spearheaded an effort to prove that Compton's interpretation of the Compton effect was wrong, and Allison became part of this effort. Duane carried out a series of meticulous experiments to disprove Compton, but instead found overwhelming evidence that Compton was correct. To his credit, Duane conceded that this was the case.
https://en.wikipedia.org/wiki?curid=2594225
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Early applications of prospect theory in International Relations emphasized the potential to explain anomalies in foreign policy decision-making that remained difficult to account for on the basis of rational choice theory. They developed detailed qualitative case studies of specific foreign policy decisions to explore the role of framing effects in choice selection. For example, Rose McDermott applied prospect theory to a series of case studies in American foreign policy, including the 1956 Suez Crisis in 1956, the U-2 Crisis in 1960, the U.S. decision to admit the Iranian shah to the United States in 1979, and the U.S. decision to carry out a hostage rescue mission in 1980. Jeffrey Berejikian employed prospect theory to analyze the genesis of the Montreal Protocol, a landmark environmental agreement.
https://en.wikipedia.org/wiki?curid=197284
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The Jha Committee proposed the setting up of a university, and the gradual development of the CPIR into a full-fledged varsity in five to ten years. This committee suggested that the CPIR could be developed as the nucleus for the varsity; CPIR be placed under a Board set up by the Goa government with cooperation from the University of Bombay; that the CPIR administrative work be carried out by an executive committee headed by a director; that it should be shifted to a suitable site; that the CPIR Board would have all powers of an educational institution including financial ones while the academic powers would be vested in the University of Bombay; that its Director be tasked with developing the CPIR into a future varsity; while other recommendations made keeping in view Goa's historical, geographic and cultural position. However, there was much discussion on various aspects of the setting up of a university, including over its venue. This finally came about in Goa not in the anticipated time-frame but only in the mid-1980s, under the Lieutenant Governorship of Dr. Gopal Singh.
https://en.wikipedia.org/wiki?curid=65752340
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Bennett was permitted to add considerably to the number of PFF Mosquito Squadrons - by May 1945 there were twelve of these, including the detached No. 627 Sqn. which was in No. 5 Group. The expanding PFF Mosquito squadrons visited all of the well-known targets in Germany including Berlin, Hamburg, Cologne, Essen, Mannheim, Hanover, and Duisburg. They took part in many bombing operations as pathfinders, marking targets with flares for the massed formations of heavy bombers. Once the B.XVI variants with enlarged bomb bays were brought into service in February 1944, they dropped 4,000-lb blast bombs ("cookies") which were used on many raids, making the force a formidable weapon in its own right. During 20/21 February to 27/28 March 1945 inclusive, No. 139 squadron made a series of 36 consecutive night attacks on Berlin with these large bombs.
https://en.wikipedia.org/wiki?curid=23908469
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There are many types of fuel cells, but they all consist of an anode, a cathode, and an electrolyte that allows ions, often positively charged hydrogen ions (protons), to move between the two sides of the fuel cell. At the anode a catalyst causes the fuel to undergo oxidation reactions that generate ions (often positively charged hydrogen ions) and electrons. The ions move from the anode to the cathode through the electrolyte. At the same time, electrons flow from the anode to the cathode through an external circuit, producing direct current electricity. At the cathode, another catalyst causes ions, electrons, and oxygen to react, forming water and possibly other products. Fuel cells are classified by the type of electrolyte they use and by the difference in startup time ranging from 1 second for proton-exchange membrane fuel cells (PEM fuel cells, or PEMFC) to 10 minutes for solid oxide fuel cells (SOFC). A related technology is flow batteries, in which the fuel can be regenerated by recharging. Individual fuel cells produce relatively small electrical potentials, about 0.7 volts, so cells are "stacked", or placed in series, to create sufficient voltage to meet an application's requirements. In addition to electricity, fuel cells produce water vapor, heat and, depending on the fuel source, very small amounts of nitrogen dioxide and other emissions. The energy efficiency of a fuel cell is generally between 40 and 60%; however, if waste heat is captured in a cogeneration scheme, efficiencies of up to 85% can be obtained.
https://en.wikipedia.org/wiki?curid=11729
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Roquefortine C is a cyclodipeptide mycotoxin derived from the diketopiperazine cyclo(Trp-dehydro-His) and is a relatively common fungal metabolite produced by a number of "Penicillium" species. It is also considered one of the most important fungal contaminants of carbonated beverages, beer, wine, meats, cheese and bread. At high doses roquefortine C is classified as a toxic compound. Although it is a potent neurotoxin at high doses, at low concentrations of 0.05 to 1.47 mg/kg that occur in domestic cheeses, it was found to be "safe for the consumer". The mechanisms underlying its toxicity and metabolism have been investigated by studying its interaction with mammalian cytochrome P450 enzymes. In addition to these toxic properties, roquefortine C reportedly possesses bacteriostatic activity against gram-positive bacteria, but only in those organisms containing haemoproteins.
https://en.wikipedia.org/wiki?curid=21677776
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In Vietnam and the United States, teratogenic or birth defects were observed in children of people who were exposed to Agent Orange or 2,4,5-T that contained TCDD as an impurity out of the production process. However there has been some uncertainty on the causal link between Agent Orange/dioxin exposure. In 2006 a meta-analysis indicated large amount of heterogeneity between studies and emphasized a lack of consensus on the issue. Still-births, cleft palate, and neural tube defects, with spina bifida were the most statistically significant defects. Later some tooth defects and borderline neurodevelopmental effects have been reported. After the Seveso accident tooth development defects, changed sex ratio and decreased sperm quality have been noted. Various developmental effects have been clearly shown after high mixed exposures to dioxins and dioxin-like compounds, the most dramatic in Yusho and Yu-chen catastrophes, in Japan and Taiwan, respectively.
https://en.wikipedia.org/wiki?curid=23789332
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Relative to esters of most carboxylic acids, esters of pivalic acid are unusually resistant to hydrolysis. Some applications result from this thermal stability. Polymers derived from pivalate esters of vinyl alcohol are highly reflective lacquers. The pivaloyl (abbreviated Piv or Pv) group is a protective group for alcohols in organic synthesis. Pivalic acid is sometimes used as an internal chemical shift standard for NMR spectra of aqueous solutions. While DSS is more commonly used for this purpose, the minor peaks from protons on the three methylene bridges in DSS can be problematic. The H NMR spectrum at 25 °C and neutral pH is a singlet at 1.08 ppm. Pivalic acid is employed as co-catalyst in some of the Palladium catalyzed C-H functionalization reaction.
https://en.wikipedia.org/wiki?curid=6811852
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After the rediscovery of Mendel's work, scientists tried to determine which molecules in the cell were responsible for inheritance. In 1900, Nettie Stevens began studying the mealworm. Over the next 11 years, she discovered that females only had the X chromosome and males had both X and Y chromosomes. She was able to conclude that sex is a chromosomal factor and is determined by the male. In 1911, Thomas Hunt Morgan argued that genes are on chromosomes, based on observations of a sex-linked white eye mutation in fruit flies. In 1913, his student Alfred Sturtevant used the phenomenon of genetic linkage to show that genes are arranged linearly on the chromosome.
https://en.wikipedia.org/wiki?curid=12266
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The study of linear algebra emerged from the study of determinants, which were used to solve systems of linear equations. Calculus had two main systems of notation, each created by one of the creators: that developed by Isaac Newton and the notation developed by Gottfried Leibniz. Leibniz's is the notation used most often today. Newton's was simply a dot or dash placed above the function. In modern usage, this notation generally denotes derivatives of physical quantities with respect to time, and is used frequently in the science of mechanics. Leibniz, on the other hand, used the letter "d" as a prefix to indicate differentiation, and introduced the notation representing derivatives as if they were a special type of fraction. This notation makes explicit the variable with respect to which the derivative of the function is taken. Leibniz also created the integral symbol. The symbol is an elongated S, representing the Latin word "Summa", meaning "sum". When finding areas under curves, integration is often illustrated by dividing the area into infinitely many tall, thin rectangles, whose areas are added. Thus, the integral symbol is an elongated s, for sum.
https://en.wikipedia.org/wiki?curid=6134187
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Using geodetic techniques, GPS networks have been used in research to constrain the velocity field throughout the Tian Shan. This type of analysis helps illustrate the distribution of shortening rates throughout the region. Most of the convergence between the Tarim Basin and the Kazakh Platform is absorbed within the Tian Shan, with localized zones of shortening at rates of ~2 mm/yr to 6 mm/yr. The total amount of convergence in the Tian Shan is not uniformly distributed across the range, with 80–90% of the North-South shortening absorbed along the southern and northern edges, and relatively little deformation accommodated within the interior. The Chinese Tian Shan displays lateral variations in magnitudes of deformation, estimates range from 2.12 to 21 km of crustal shortening. Slip rates on NW-SE trending strike-slip faults range from 1–4 mm/yr. Slip rates on WE-SN trending gently-dipping detachment fault vary from 10–13 mm/yr for the southwest Tian Shan to 2–5 mm/y for eastern Tian Shan. The velocity field indicates that the Tarim Basin is thrusting beneath the Tian Shan at ~4–7 mm/yr. The velocity field also places a bound of ~4 mm/yr on the rate of crustal shortening across the Chatkal and neighboring ranges on the northwest margin of the Ferghana Valley, and they limit the present day slip rate on the right lateral Talas-Ferghana Fault to less than ~2 mm/yr
https://en.wikipedia.org/wiki?curid=33758084
1,917,863
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Designed by Aurelio Lampredi, the Fiat 124 engine first appeared in the all-new Fiat 124 in April 1966. The in-line four-cylinder engine comprised an iron block with an aluminium cylinder-head with pushrod actuated valves. The belt-driven design was ahead of its time when introduced. European production of the petrol versions ended with the Fiat 131 in 1984, but later diesel derivatives continued to be built until 1999. It did have a longer life in its twin-cam iteration, which continued in production until 2000. While originally of an overhead valve design, an overhead cam version was added to the facelifted 131 in 1981. The capacity was initially (in the Fiat 124), but eventually ranged between . There were also three SOHC diesel iterations of 1.4, 1.7, and 1.9 litres. The last versions of this engine to be built were the diesels. The direct-injected diesel version was the first direct-injection diesel to appear in a production passenger car, the Fiat Croma Turbo D i.d.
https://en.wikipedia.org/wiki?curid=38510060
1,662,010
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The London mayor called for an E-revolution in March 2009 and he presented the "Electric Delivery Plan for London" in May 2009. The plan projects 25,000 charging points London by 2015 including 500 on-street, 2000 off-street in car-parks and 22,000 privately owned locations. London itself will buy 1000 electric vehicles up to 2015. Owners of an electric car will not need to pay the Congestion Charge for the city of London being worth up to £1,700 a year. At that point (May 2009) London already had 100 charge points in public places which will be increased to 250 by 2012. Beginning 2011 20% of new lots in car parks must have access to a charging outlet. Additionally, the parking in the Westminster boroughs will be free for electric vehicles saving the user up to £6,000 a year and a flat rate of £200 electricity cost is charged for the usage of public outlets in Westminster.
https://en.wikipedia.org/wiki?curid=21079741
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A third practical concern is the melting of permafrost due to climate change. Degradation of this permafrost is leading to major ground surface subsidence and pounding. The ground is literally melting away in many regions of the Arctic. The locations of towns and communities that have been inhabited for centuries are now in jeopardy. A condition known as drunken tree syndrome is being caused by this melting. Ground water and river runoffs are being negatively impacted as well. Although warming conditions might increase uptake for photosynthetic organisms in some places, scientists are concerned that melting permafrost will also release large amounts of carbon locked in permafrost. Higher temperatures increase soil decomposition and if soil decomposition becomes higher than net primary production, global atmospheric carbon dioxide will in turn increase. Atmospheric sinks in the water table are also being reduced as the permafrost melts and decreases the height of the water table in the Arctic.
https://en.wikipedia.org/wiki?curid=11180149
1,513,146
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Beginning in 2007, the British Engineering and Physical Sciences Research Council has funded development of ribosome-like molecular assemblers. Clearly, molecular assemblers are possible in this limited sense. A technology roadmap project, led by the Battelle Memorial Institute and hosted by several U.S. National Laboratories has explored a range of atomically precise fabrication technologies, including both early-generation and longer-term prospects for programmable molecular assembly; the report was released in December, 2007. In 2008, the Engineering and Physical Sciences Research Council provided funding of £1.5 million over six years (£1,942,235.57, $2,693,808.00 in 2021) for research working towards mechanized mechanosynthesis, in partnership with the Institute for Molecular Manufacturing, amongst others.
https://en.wikipedia.org/wiki?curid=294218
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Many problems in data analysis concern clustering, grouping data items into clusters of closely related items. Hierarchical clustering is a version of cluster analysis in which the clusters form a hierarchy or tree-like structure rather than a strict partition of the data items. In some cases, this type of clustering may be performed as a way of performing cluster analysis at multiple different scales simultaneously. In others, the data to be analyzed naturally has an unknown tree structure and the goal is to recover that structure by performing the analysis. Both of these kinds of analysis can be seen, for instance, in the application of hierarchical clustering to biological taxonomy. In this application, different living things are grouped into clusters at different scales or levels of similarity (species, genus, family, etc). This analysis simultaneously gives a multi-scale grouping of the organisms of the present age, and aims to accurately reconstruct the branching process or evolutionary tree that in past ages produced these organisms.
https://en.wikipedia.org/wiki?curid=33068704
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The pathogenesis of lipoprotein-X in cholestasis is not totally resolved. Normally, the liver excretes lipoprotein complexes into the bile showing phospholipid and unesterified cholesterol concentrations similar to Lipoprotein-X. The in vitro incubation of these bile lipoproteins with serum or albumin leads to the appearance of Lp-X–like particles. These findings suggest that the reflux of bile into the plasma compartment causes the formation of lipoprotein-X in cholestasis as a result of a physicochemical, nonmetabolic process. On the other hand, lipoprotein-X particles found in familial LCAT deficiency are identical to those in cholestasis regarding ultrastructure and biochemical composition. It has been supposed that reduced LCAT activities, common in patients with hepatocellular disease, cause, alone or in combination with other factors, the formation of Lipoprotein-X in cholestasis. Lipoprotein-X is mainly removed by the reticuloendothelial system of the liver and the spleen, as shown by studies using radioactively labeled lipoprotein-X in rats. Other organs, such as the kidney, also actively clear Lipoprotein-X from the plasma.
https://en.wikipedia.org/wiki?curid=4467938
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The ideas behind HOTOL originated from work done by British Engineer Alan Bond in the field of pre-cooled jet engines. Bond had specifically performed this research with the intention of producing a viable engine for powering a space launch system. In 1982, British Aerospace (BAe), which was Europe's principal satellite-builder, began studying a prospective new launch system with the aim of providing launch costs that were 20 per cent of the American Space Shuttle operated by NASA. BAe became aware of work by British engine manufacturer Rolls-Royce on a suitable engine, and soon conceived of an unmanned, fully reusable single-stage-to-orbit (SSTO) winged spaceplane as a launch vehicle.
https://en.wikipedia.org/wiki?curid=14301
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ISDN is used heavily by the broadcast industry as a reliable way of switching low-latency, high-quality, long-distance audio circuits. In conjunction with an appropriate codec using MPEG or various manufacturers' proprietary algorithms, an ISDN BRI can be used to send stereo bi-directional audio coded at 128 kbit/s with 20 Hz – 20 kHz audio bandwidth, although commonly the G.722 algorithm is used with a single 64 kbit/s B channel to send much lower latency mono audio at the expense of audio quality. Where very high quality audio is required multiple ISDN BRIs can be used in parallel to provide a higher bandwidth circuit switched connection. BBC Radio 3 commonly makes use of three ISDN BRIs to carry 320 kbit/s audio stream for live outside broadcasts. ISDN BRI services are used to link remote studios, sports grounds and outside broadcasts into the main broadcast studio. ISDN via satellite is used by field reporters around the world. It is also common to use ISDN for the return audio links to remote satellite broadcast vehicles.
https://en.wikipedia.org/wiki?curid=15231
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In 2011, American palaeontologists Kevin Padian and John R. Horner proposed that "bizarre structures" in dinosaurs in general (including domes, frills, horns, and crests) were primarily used for species recognition, and dismissed other explanations as unsupported by evidence. Among other studies, these authors cited Goodwin et al.'s 2004 paper on pachycephalosaur domes as support of this idea, and they pointed out that such structures did not appear to be sexually dimorphic. In a response to Padian and Horner the same year, Rob J. Knell and Scott D. Sampson argued that species recognition was not unlikely as a secondary function for "bizarre structures" in dinosaurs, but that sexual selection (used in display or combat to compete for mates) was a more likely explanation, due to the high cost of developing them, and because such structures appear to be highly variable within species. In 2013, the British palaeontologists David E. Hone and Darren Naish criticized the "species recognition hypothesis", and argued that no extant animals use such structures primarily for species recognition, and that Padian and Horner had ignored the possibility of mutual sexual selection (where both sexes are ornamented).
https://en.wikipedia.org/wiki?curid=2274197
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Opaque sets were originally studied by Stefan Mazurkiewicz in 1916. Other early works on opaque sets include the papers of H. M. Sen Gupta and N. C. Basu Mazumdar in 1955, and by Frederick Bagemihl in 1959, but these are primarily about the distance sets and topological properties of barriers rather than about minimizing their length. In a postscript to his paper, Bagemihl asked for the minimum length of an interior barrier for the square, and subsequent work has largely focused on versions of the problem involving length minimization. They have been repeatedly posed, with multiple colorful formulations: digging a trench of as short a length as possible to find a straight buried telephone cable, trying to find a nearby straight road while lost in a forest, swimming to a straight shoreline while lost at sea, efficiently painting walls to render a glass house opaque, etc.
https://en.wikipedia.org/wiki?curid=41162601
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At a 1928 medical conference in Battle Creek, Michigan, Papanicolaou introduced his low-cost, easily performed screening test for early detection of cancerous and precancerous cells. However, this potential medical breakthrough was initially met with skepticism and resistance from the medical community. Papanicolaou's next communication on the subject did not appear until 1941 when, with gynecologist Herbert Traut, he published a paper on the diagnostic value of vaginal smears in carcinoma of the uterus. This was followed two years later by an illustrated monograph based on a study of over 3,000 cases. In 1954, he published another memorable work, the "Atlas of Exfoliative Cytology", thus creating the foundation of the modern medical specialty of cytopathology.
https://en.wikipedia.org/wiki?curid=155030
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Clinical Microbiology Reviews is a peer-reviewed medical journal covering the areas of clinical microbiology, immunology, medical microbiology, infectious diseases, veterinary microbiology, and microbial pathogenesis. It is a delayed open access journal, full content is accessible via PubMed Central and the journal's website after a 12-month embargo. In April 2015, the journal transitioned to a continuous online publication model (whereby articles are published as they become ready, before the issue in which they will appear has been finalized). The journal became online-only in January 2018. The final print issue was published in October 2017. According to the "Journal Citation Reports", the journal has a 2021 impact factor of 50.129. The journal was established in January 1988. The founding editor was Josephine A. Morello (University of Chicago Medical Center). Editorial board structure changed in 1992 and Morello became editor-in-chief. Betty Ann Forbes (State University of New York) was appointed editor-in-chief in 1997. Irving Nachamkin (University of Pennsylvania) was appointed editor-in-chief in 2002 until 2012. Since 2012, Jo-Anne H. Young (University of Minnesota) has served as editor-in-chief. It is the ninth journal established and published by the American Society for Microbiology.
https://en.wikipedia.org/wiki?curid=9793000
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By the 9th century AD, the unity brought about by the Islamic conquest of North Africa and the expansion of Islamic culture came to an end. Conflict arose as to who should be the successor of the prophet. The Umayyads had initially taken control of the Caliphate, with their capital at Damascus. Later, the Abbasids had taken control, moving the capital to Baghdad. The Berber people, being independent in spirit and hostile to outside interference in their affairs and to Arab exclusivity in orthodox Islam, adopted Shi'ite and Kharijite Islam, both considered unorthodox and hostile to the authority of the Abbasid Caliphate. Numerous Kharijite kingdoms came and fell during the 8th and 9th centuries, asserting their independence from Baghdad. In the early 10th century, Shi'ite groups from Syria, claiming descent from Muhammad's daughter Fatimah, founded the Fatimid dynasty in the Maghreb. By 950, they had conquered all of the Maghreb and by 969 all of Egypt. They had immediately broken away from Baghdad.
https://en.wikipedia.org/wiki?curid=14099
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PCR amplification of the DNA target occurs in three steps: denaturation, annealing and extension. Each of these steps occur at a specific temperature for a fixed period of time. Denaturation is normally allowed to occur between 90 and 95 °C and leads to the dissociation of DNA strands. After this the reaction is cooled to between 40 and 70 °C to allow the primers to associate with their respective target sequences. This step is known as the annealing step and is primer specific. The temperature at which the primers anneal is critical. Too high temperatures would not allow the primers to associate with the DNA, resulting in no or poor amplification. Too low annealing temperature would ultimately lead to non-specific binding of the primers and non-specific amplification. Primers bound to the regions flanking the target DNA provide 3’-hydroxyl groups for DNA polymerase catalyzed extension. The most commonly used DNA polymerase is Taq, a thermo-stable enzyme isolated from the thermophilic bacterium, "Thermus aquaticus". The DNA polymerase synthesizes new DNA strands along the template strands, using the primers as starting points. During the extension step the strands are amplified beyond the target DNA. This means that each newly synthesized strand of DNA will have a region complementary to a primer. There is an exponential increase in the amount of DNA produced as the three above mentioned steps are repeated in a cyclic fashion. In a traditional PCR these steps might be repeated 20 to 55 times. A problem, however, with PCR amplification is that the temperature required for DNA strand dissociation also results in DNA polymerase denaturation. This is partially overcome by the bioengineering of polymerases which are more thermal stable and have longer half-lives.
https://en.wikipedia.org/wiki?curid=12386405
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The Porsche 919 Hybrid is a Le Mans Prototype 1 (LMP1) racing car built and used by Porsche in the 2014, 2015, 2016 and 2017 seasons of the FIA World Endurance Championship. It has a 90-degree V4 mid-mounted mono-turbocharged petrol engine that produces and acts as a chassis load-bearing member - and two separate energy-recovery hybrid systems to recover thermal energy from exhaust gases and convert kinetic energy into electrical energy under braking for storage into lithium-ion battery packs. In accordance with the 2014 regulations, the vehicle was placed in the class.
https://en.wikipedia.org/wiki?curid=41368349
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In modern form, the Klopman-Salem equation is commonly given asformula_1,where formula_2 is the electron population in atomic orbital "a",formula_3, formula_4 are the resonance and overlap integrals for the interaction of atomic orbitals "a" and "b",formula_5 is the total charge on atom "k",formula_6 is the local dielectric constant,formula_7 is the distance between the nuclei of atoms "k" and "l",formula_8 is the coefficient of atomic orbital "a" in molecular orbital "r",and formula_9 is the energy of molecular orbital "r".Broadly speaking, the first term describes the closed-shell repulsion of the occupied molecular orbitals of the reactants (four-electron filled-filled interactions, "steric effects"). The second term describes the Coulombic attraction or repulsion between the atoms of the reactants (ionic contribution, "electrostatic effects"). Finally, the third term accounts for all possible interactions between the occupied and unoccupied molecular orbitals of the reactants (two-electron filled-unfilled interactions, "stereoelectronic effects"). Although conceptually useful, the Klopman-Salem equation seldom serves as the basis for energetic analysis in modern quantum chemical calculations.
https://en.wikipedia.org/wiki?curid=56098547
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In 1927, Deming was introduced to Walter A. Shewhart of the Bell Telephone Laboratories by C.H. Kunsman of the United States Department of Agriculture (USDA). Deming found great inspiration in the work of Shewhart, the originator of the concepts of statistical control of processes and the related technical tool of the control chart, as Deming began to move toward the application of statistical methods to industrial production and management. Shewhart's idea of common and special causes of variation led directly to Deming's theory of management. Deming saw that these ideas could be applied not only to manufacturing processes, but also to the processes by which enterprises are led and managed. This key insight made possible his enormous influence on the economics of the industrialized world after 1950.
https://en.wikipedia.org/wiki?curid=70534
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For somewhat greater than 128 bits of security, Singh presents a set of parameters which have 6956-bit public keys for the Peikert's scheme. The corresponding private key would be roughly 14,000 bits. An RLWE version of the classic MQV variant of a Diffie–Hellman key exchange was later published by Zhang et al. in 2014. The security of both key exchanges is directly related to the problem of finding approximate short vectors in an ideal lattice. This article will closely follow the RLWE work of Ding in "A Simple Provably Secure Key Exchange Scheme Based on the Learning with Errors Problem". For this presentation a typical polynomial is expressed as:
https://en.wikipedia.org/wiki?curid=46733414
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Umbriel orbits Uranus at the distance of about , being the third farthest from the planet among its five major moons. Umbriel's orbit has a small eccentricity and is inclined very little relative to the equator of Uranus. Its orbital period is around 4.1 Earth days, coincident with its rotational period. In other words, Umbriel is a synchronous or tidally locked satellite, with one face always pointing toward its parent planet. Umbriel's orbit lies completely inside the Uranian magnetosphere. This is important, because the trailing hemispheres of airless satellites orbiting inside a magnetosphere (like Umbriel) are struck by magnetospheric plasma, which co-rotates with the planet. This bombardment may lead to the darkening of the trailing hemispheres, which is actually observed for all Uranian moons except Oberon (see below). Umbriel also serves as a sink of the magnetospheric charged particles, which creates a pronounced dip in energetic particle count near the moon's orbit as observed by "Voyager 2" in 1986.
https://en.wikipedia.org/wiki?curid=32101
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A copper indium gallium selenide solar cell or CIGS cell uses an absorber made of copper, indium, gallium, selenide (CIGS), while gallium-free variants of the semiconductor material are abbreviated CIS. It is one of three mainstream thin-film technologies, the other two being cadmium telluride and amorphous silicon, with a lab-efficiency above 20 percent and a share of 2 percent in the overall PV market in 2013. A prominent manufacturer of cylindrical CIGS-panels was the now-bankrupt company Solyndra in Fremont, California. Traditional methods of fabrication involve vacuum processes including co-evaporation and sputtering. In 2008, IBM and Tokyo Ohka Kogyo Co., Ltd. (TOK) announced they had developed a new, non-vacuum, solution-based manufacturing process for CIGS cells and are aiming for efficiencies of 15% and beyond.
https://en.wikipedia.org/wiki?curid=20386463
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The Schepens Eye Research Institute, formerly known as the Retina Foundation Institute of Biological and Medical Sciences, is an independent nonprofit research foundation founded by ophthalmologist Charles Schepens that operates as part of the research program of Massachusetts Eye and Ear. In 1976, singer Ella Fitzgerald performed a benefit concert to show appreciation after her medical procedure. Doctors from the foundation occasionally travelled to India to perform operations for villagers. By 1964, 14 years after its establishment, the foundation had 88 staff members and received 60 percent of its funding from the government and the rest from private sector contributions. Frances Todman was named chairperson in 1985. She was a member of the national board of trustees and the corporation board. In 1986, the foundation employed over 100 researchers.
https://en.wikipedia.org/wiki?curid=66170910
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In 1998, Dr. Anthony Carpi, an environmental chemist and then-assistant professor at John Jay College of the City University of New York, designed and launched a prototype Internet learning resource for science students, called The Natural Science Pages. This was in part a response to the growing evidence that poor textbook content and deficient teaching materials contribute to inadequate science education. The purpose of the prototype was to see if presenting important course information in a new form would improve what students understood, what information they remembered, and how well they performed in their class overall.
https://en.wikipedia.org/wiki?curid=27140072
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To explain natural selection, Darwin drew an analogy with humans modifying animals through artificial selection, whereby animals were selectively bred for specific traits, which has given rise to individuals that no longer resemble their wild ancestors. Darwin argued that in the natural world, it was nature that played the role of humans in selecting for specific traits. He came to this conclusion based on two observations and two inferences. First, members of any population tend to vary with respect to their heritable traits. Second, all species tend to produce more offspring than can be supported by their respective environments, resulting in many individuals not surviving and reproducing. Based on these observations, Darwin inferred that those individuals who possessed heritable traits that are better adapted to their environments are more likely to survive and produce more offspring than other individuals. He further inferred that the unequal or differential survival and reproduction of certain individuals over others will lead to the accumulation of favorable traits over successive generations, thereby increasing the match between the organisms and their environment. Thus, taken together, natural selection is the differential survival and reproduction of individuals in subsequent generations due to differences in or more heritable traits.
https://en.wikipedia.org/wiki?curid=9127632
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Nora Bredes, executive director of the Shoreham Opponents Coalition, was a primary organizer of the grass-roots campaign against Shoreham during the 1980s. She lobbied officials, organized advertising campaigns, wrote pamphlets, and planned rallies. Ms. Bredes drew together more than two dozen local opposition groups which included the Lloyd Harbor Study Group, the Farm Bureau, The Long Island Safe Energy Coalition and its newsletter Chain Reaction, Safe'n Sound with its "Sound Times" newspaper, and the S.H.A.D. Alliance (modeled on New Hampshire's Clamshell Alliance). According to a Newsday poll, in 1981, 43 percent of Long Islanders opposed the plant; by 1986, that number had risen to 74 percent.
https://en.wikipedia.org/wiki?curid=2046186
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Though his relationship with co-workers was typically hostile, he was social enough to give a demonstration of his harness to a small group. He showed how the metal tentacles allowed him to work safely with chemicals that would normally be too dangerous for a human being to touch or be in close vicinity to. One such person impressed by this was a scientist named Mary Alice Anders, and the two soon dated. In due time, Otto proposed marriage to Mary Alice. However, when Otto joyously announced his future marriage to his mother, her feelings were not reciprocated. Believing that no woman was good enough for her son, she made him feel guilty that she was going to be pushed aside for his bride-to-be. Shocked that he hurt his mother, and to please her, Otto broke off the engagement with Mary Alice. Later, when he discovered that his mother had begun dating a librarian, he rebuked her, causing her to have a fatal heart attack in the heat of their argument. With the death of his mother and Mary Alice Anders out of his life, Octavius' disposition towards nearly everyone became mean-spirited, and he had become more distracted from paying attention to detail and safety precautions in his work. His co-workers often called him "Doctor Octopus" behind his back, a pun on his actual name inspired by the four-armed apparatus; he was aware of this insult, but he barely cared.
https://en.wikipedia.org/wiki?curid=315873
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The metabolic disorder, lysinuric protein intolerance is caused by the body's inability to digest and use certain protein building blocks or amino acids. These are lysine, arginine, and ornithine. These amino acids are found in many protein-rich foods. Since in this disorder the human body cannot effectively break down these amino acids people typically experience nausea and vomiting after ingesting protein rich foods. Associated features of this protein intolerance may include an enlarged liver and spleen, short stature, muscle weakness, impaired immune function, and progressively brittle bones that are prone to fracture and a lung disorder called pulmonary alveolar proteinosis may also develop. In addition, the accumulation of amino acids in the kidneys can cause end-stage renal disease (ESRD). In ESRD the kidneys are no longer able to filter fluids and waste products from the body effectively.
https://en.wikipedia.org/wiki?curid=43809874
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The development team consisted of Fujita in charge of planning, with Tsujino providing level design and graphics and two others programming the arcade board, a modified version of the Taito Classic hardware. The neon, futuristic aesthetic was inspired by the film "Tron" (1982), which Tsujino was a big fan of. Blocks originally never had colors and were simply the same color, which was changed to the minor annoyance of Tsujino. The various geometric-like enemies and power-up items were hand-drawn from 3-dimensional models before being converted into sprite art. Hisayoshi Ogura, the founder of Taito's "house band" Zuntata, created the game's music.
https://en.wikipedia.org/wiki?curid=176965
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A major problem for the pioneers in VS neurosurgery was the lack of adequate imaging for spotting small tumors. Treating tumors that grew overly large in the cerebellopontine angle resulted in poor outcomes for the goals of facial nerve and hearing preservation. For imaging, conventional X-rays began to be used in the 1920s and CT scanners were introduced in the 1960s, but all were superseded by 'gold standard' MRIs in the 1980s. Facial nerve monitoring was added in 1979. William F. House (1923–2012) pioneered the use of the operating microscope, and (with William Hitselberger) popularized the translabyrinthine and middle fossa surgery approaches for VS. The operating microscope would be used in virtually all operations by 1998. House's son, John W. House, proposed (1983) and, with Derald E. Brackmann, developed the House-Brackmann grading system for reporting facial nerve outcomes following VS surgery.
https://en.wikipedia.org/wiki?curid=1002770
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Color-glass condensate is a type of matter theorized to exist in atomic nuclei traveling near the speed of light. According to Einstein's theory of relativity, a high-energy nucleus appears length contracted, or compressed, along its direction of motion. As a result, the gluons inside the nucleus appear to a stationary observer as a "gluonic wall" traveling near the speed of light. At very high energies, the density of the gluons in this wall is seen to increase greatly. Unlike the quark–gluon plasma produced in the collision of such walls, the color-glass condensate describes the walls themselves, and is an intrinsic property of the particles that can only be observed under high-energy conditions such as those at RHIC and possibly at the Large Hadron Collider as well.
https://en.wikipedia.org/wiki?curid=37461
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Both Dieter Sattler's parents had been born in Florence where their own parents spent time as members of the expatriate artistic community. Dieter Sattler spent several months each year in Florence while a small child, but this routine came to an end in 1914, the year war broke out, and in 1915 he started to attend his secondary school in Munich. His parents separated in 1921. The children remained with their mother whose conversion to Roman Catholicism, (after growing up with parents who "had no Christian faith") had been a reason for the break-up. He passed his School Final Exams (Abitur) at the city's prestigious Wilhelmsgymnasium (secondary school) in 1924. Dieter Sattler himself would convert to Catholicism only in 1932, his decision to do so influenced both by the woman who shortly afterwards became his wife and by his intellectually formidable maternal uncle, Dietrich von Hildebrand (1889-1977), whose own conversion to Catholicism had taken place in 1914.
https://en.wikipedia.org/wiki?curid=54975038
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IBM® TS4300 Tape Library is a high-density, highly scalable, easy-to-manage solution designed to keep data securely stored long-term, while helping reduce the costs associated with data center space and utilities. Its modular design enables you to increase cartridge and drive capacity as needed—scale vertically up to seven modules with expansion for Linear Tape-Open (LTO) Ultrium cartridges, drives and redundant power supplies. IBM TS4300 enhanced modern data protection helps meet security and compliance requirements.
https://en.wikipedia.org/wiki?curid=8453590
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Piezo-electric current therapy, or PECT, is an analgesic technique based on the principle that mechanical deformation of a motorized piezoelectric ceramic rod produces a burst of 10 electrical pulses (five positive and five negative), each lasting 2–3 ms. Each electrical burst lasts for 50 to 250 ms (depending on the motor speed set) and generates a current of approximately 25 mA. The application of PECT to the skin for 2 min produces a tolerable "pricking" pain sensation associated with a neurogenic inflammatory response lasting 3–4 h. The extent and duration of this inhibitory process is directly related to the intensity of the applied stimulus and is alleged to be associated with the release of endogenous endorphins.
https://en.wikipedia.org/wiki?curid=22551311
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In 2005, an independent review by the JASON Defense Advisory Group that was generally positive, concluded that "The scientific and technical challenges in such a complex activity suggest that success in the early attempts at ignition in 2010, while possible, is unlikely". On January 26, 2009, the final line replaceable unit (LRU) was installed, unofficially completing construction. On February 26, 2009, NIF fired all 192 laser beams into the target chamber. On March 10, 2009, NIF became the first laser to break the megajoule barrier, delivering 1.1 MJ of UV light, known as 3ω (from third harmonic generation), to the target chamber center in a shaped ignition pulse. The main laser delivered 1.952 MJ of IR.
https://en.wikipedia.org/wiki?curid=337301
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Another important factor leading to the absence of wide adoption of any existing upper ontology is the complexity. Some upper ontologies Cyc is often cited as an example in this regard—are very large, ranging up to thousands of elements (classes, relations), with complex interactions among them and with a complexity similar to that of a human natural language, and the learning process can be even longer than for a natural language because of the unfamiliar format and logical rules. The motivation to overcome this learning barrier is largely absent because of the paucity of publicly accessible examples of use. As a result, those building domain ontologies for local applications tend to create the simplest possible domain-specific ontology, not related to any upper ontology. Such domain ontologies may function adequately for the local purpose, but they are very time-consuming to relate accurately to other domain ontologies.
https://en.wikipedia.org/wiki?curid=3200382
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Early cephalopods are thought to have produced jets by drawing their body into their shells, as "Nautilus" does today. "Nautilus" is also capable of creating a jet by undulations of its funnel; this slower flow of water is more suited to the extraction of oxygen from the water. When motionless, "Nautilus" can only extract 20% of oxygen from the water. The jet velocity in "Nautilus" is much slower than in coleoids, but less musculature and energy is involved in its production. Jet thrust in cephalopods is controlled primarily by the maximum diameter of the funnel orifice (or, perhaps, the average diameter of the funnel) and the diameter of the mantle cavity. Changes in the size of the orifice are used most at intermediate velocities. The absolute velocity achieved is limited by the cephalopod's requirement to inhale water for expulsion; this intake limits the maximum velocity to eight body-lengths per second, a speed which most cephalopods can attain after two funnel-blows. Water refills the cavity by entering not only through the orifices, but also through the funnel. Squid can expel up to 94% of the fluid within their cavity in a single jet thrust. To accommodate the rapid changes in water intake and expulsion, the orifices are highly flexible and can change their size by a factor of twenty; the funnel radius, conversely, changes only by a factor of around 1.5.
https://en.wikipedia.org/wiki?curid=42726
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Gliese 581c is the third planet orbiting Gliese 581. It was discovered in April 2007. In their 2007 paper, Udry et al. asserted that if Gliese 581c has an Earth-type composition, it would have a radius of 1.5R, which would have made it at the time "the most Earth-like of all known exoplanets". A direct measurement of the radius cannot be taken because, viewed from Earth, the planet does not transit its star. The minimum mass of the planet is 5.5 times that of Earth. The planet initially attracted attention as being potentially habitable, though this has since been discounted. The mean blackbody surface temperature has been estimated to lie between −3 °C (for a Venus-like albedo) and 40 °C (for an Earth-like albedo), however, the temperatures could be much higher (about 500 degrees Celsius) due to a runaway greenhouse effect akin to that of Venus. Some astronomers believe the system may have undergone planetary migration and Gliese 581c may have formed beyond the frost line, with a composition similar to icy bodies like Ganymede. Gliese 581c completes a full orbit in just under 13 days.
https://en.wikipedia.org/wiki?curid=2758531
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In 2016, Madeline C. Weiss and colleagues genetically analyzed 6.1 million protein-coding genes and 286,514 protein clusters from sequenced prokaryotic genomes representing many phylogenetic trees, and identified 355 protein clusters that were probably common to the LUCA. The results "depict LUCA as anaerobic, CO-fixing, H-dependent with a Wood–Ljungdahl pathway (the reductive acetyl-coenzyme A pathway), N-fixing and thermophilic. LUCA's biochemistry was replete with FeS clusters and radical reaction mechanisms." The cofactors also reveal "dependence upon transition metals, flavins, S-adenosyl methionine, coenzyme A, ferredoxin, molybdopterin, corrins and selenium. Its genetic code required nucleoside modifications and S-adenosylmethionine-dependent methylations." The results are rather specific: they show that methanogenic clostridia was basal, near the root of the phylogenetic tree, in the 355 protein lineages examined, and that the LUCA may therefore have inhabited an anaerobic hydrothermal vent setting in a geochemically active environment rich in H, CO, and iron,
https://en.wikipedia.org/wiki?curid=1301827
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The Basic Parachute Course is four weeks long for regular troops. During that time, trainees are instructed in exit, flight and landing techniques. They are required to complete four descents, one at night, to qualify for their 'wings'. Exit training is carried out from full-size mock ups of C-130 Hercules and Skyvan fuselages. In groups of eight, each with its own RAF Parachute Jumping Instructor (PJI), trainees are taught the techniques of jumping individually and in 'sticks', both with and without equipment. Trainees are taught flight drills while suspended from the hangar roof in parachute harnesses on cables. They learn to control their parachutes while descending, and to carry out emergency measures such as untwisting their rigging lines, taking the necessary action on colliding with another parachutist, and landing in water. Parachute Landing Falls, or PLFs, for landing safely are taught using rubber mats. As trainees become more proficient, the height from which they jump is increased by the use of steps and eventually ramps which they run and jump off. Forward, side and backwards landings are practiced on a six-sided trapeze from which the trainees hang by their hands while being swung in the air. On the command of the PJI, trainees let go and perform the appropriate roll on landing.
https://en.wikipedia.org/wiki?curid=19623635
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Mechanical computers reached their zenith during World War II, when they formed the basis of complex bombsights including the Norden, as well as the similar devices for ship computations such as the US Torpedo Data Computer or British Admiralty Fire Control Table. Noteworthy are mechanical flight instruments for early spacecraft, which provided their computed output not in the form of digits, but through the displacements of indicator surfaces. From Yuri Gagarin's first manned spaceflight until 2002, every manned Soviet and Russian spacecraft Vostok, Voskhod and Soyuz was equipped with a "Globus" instrument showing the apparent movement of the Earth under the spacecraft through the displacement of a miniature terrestrial globe, plus latitude and longitude indicators.
https://en.wikipedia.org/wiki?curid=13110872
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Trichothecenes are a group of over 150 chemically related mycotoxins. Each trichothecene displays a core structure consisting of a single six-membered ring containing a single oxygen atom, flanked by two carbon rings. This core ring structure contains an epoxide, or tricyclic ether, at the 12,13 carbon positions, as well as a double bond at the 9, 10 carbon positions. These two functional groups are primarily responsible for trichothecene ability to inhibit protein synthesis and incur general cytotoxic effects. Notably, this core structure is amphipathic, containing both polar and non polar parts. All trichothecenes are related through this common structure, but each trichothecene also has a unique substitution pattern of oxygen containing functional groups at possible sites on carbons 3,4,7,8, and 15. These functional groups govern the properties of an individual tricothecene and also serve as the basis for the most commonly used classification system for this family of toxins. This classification system breaks up the trichothecene family into four groups: Type A, B, C, and D.
https://en.wikipedia.org/wiki?curid=3687230
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In the 2018 season, he played 54 games across all competitions, scoring an impressive 13 goals, second in the scoring charts only to forward Yuma Suzuki as Kashima finished the league season in 3rd place. In cup competitions, Doi scored the only goal of the 2018 Emperor's Cup quarter-final against Ventforet Kofu, where Kashima eventually lost in the semi-finals. He also scored in the second leg of the 2018 J.League Cup semi-final against Yokohama F. Marinos, but it wasn't enough to avoid an agonising 4-3 aggregate defeat. The overriding achievement of the year was the 2018 AFC Champions League win – the first time Kashima had won the competition. Doi played a part in 13 of the 14 games on the road to the finals, scoring 3 goals – including at the quarter final stage in a 3-0 victory over Tianjin Quanjian. He also started both games in the finals against Persepolis. The victory meant that Kashima would once again take part in the Club World Cup, where after a 3-2 victory over Guadalajara in which Doi won the man of the match award, they progressed to the semi-final to once again play Real Madrid. Before the semi-final, Doi himself said he was "delighted" to play against Real Madrid again. Madrid ended up as comfortable 3-1 winners, but Doi managed to score a consolation goal, in spite of a VAR review.
https://en.wikipedia.org/wiki?curid=34056443
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Oxygen consumption (VO) during exercise is best described by the Fick Equation: VO=Q x (a-vOdiff), which states that the amount of oxygen consumed is equal to cardiac output (Q) multiplied by the difference between arterial and venous oxygen concentrations. More simply put, oxygen consumption is dictated by the quantity of blood distributed by the heart as well as the working muscle's ability to take up the oxygen within that blood; however, this is a bit of an oversimplification. Although cardiac output is thought to be the limiting factor of this relationship in healthy individuals, it is not the only determinant of VO2 max. That is, factors such as the ability of the lung to oxygenate the blood must also be considered. Various pathologies and anomalies cause conditions such as diffusion limitation, ventilation/perfusion mismatch, and pulmonary shunts that can limit oxygenation of the blood and therefore oxygen distribution. In addition, the oxygen carrying capacity of the blood is also an important determinant of the equation. Oxygen carrying capacity is often the target of exercise (ergogenic aids) aids used in endurance sports to increase the volume percentage of red blood cells (hematocrit), such as through blood doping or the use of erythropoietin (EPO). Furthermore, peripheral oxygen uptake is reliant on a rerouting of blood flow from relatively inactive viscera to the working skeletal muscles, and within the skeletal muscle, capillary to muscle fiber ratio influences oxygen extraction.
https://en.wikipedia.org/wiki?curid=395477
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Simplicius mentions that Anaximander said all these "in poetic terms", meaning that he used the old mythical language. The goddess Justice (Dike) keeps the cosmic order. This concept of returning to the element of origin was often revisited afterwards, notably by Aristotle, and by the Greek tragedian Euripides: "what comes from earth must return to earth." Friedrich Nietzsche, in his "Philosophy in the Tragic Age of the Greeks", stated that Anaximander viewed "... all coming-to-be as though it were an illegitimate emancipation from eternal being, a wrong for which destruction is the only penance." Physicist Max Born, in commenting upon Werner Heisenberg's arriving at the idea that the elementary particles of quantum mechanics are to be seen as different manifestations, different quantum states, of one and the same “primordial substance,”' proposed that this primordial substance be called "apeiron".
https://en.wikipedia.org/wiki?curid=1168
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ISRO's Human Space Flight Centre and Glavcosmos, which is a subsidiary of the Russian state corporation Roscosmos, signed an agreement on 1 July 2019 for cooperation in the selection, support, medical examination and space training of four Indian astronauts. An ISRO Technical Liaison Unit (ITLU) has been approved to be set up in Moscow for coordination activities. Until September 2019, level 1 of astronaut selection process was completed in Bengaluru. Selected Test Pilots underwent physical exercise tests, lab investigations, radiological tests, clinical tests and evaluation on various facets of their psychology. By November 2019 the Indian Air Force had selected 12 potential astronauts who will then go to Russia for further training in two batches.
https://en.wikipedia.org/wiki?curid=7818844
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In his last years Verdi undertook a number of philanthropic ventures, publishing in 1894 a song for the benefit of earthquake victims in Sicily, and from 1895 onwards planning, building and endowing a rest-home for retired musicians in Milan, the Casa di Riposo per Musicisti, and building a hospital at Villanova sull'Arda, close to Busseto. His last major composition, the choral set of "Four sacred pieces", was published in 1898. In 1900 he was deeply upset at the assassination of King Umberto and sketched a setting of a poem in his memory but was unable to complete it. While staying at the Grand Hotel, Verdi suffered a stroke on 21 January 1901. He gradually grew more feeble over the next week, during which Stolz cared for him, and died on 27 January at the age of 87.
https://en.wikipedia.org/wiki?curid=12958
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Peter Raymond Grant (born October 26, 1936) and Barbara Rosemary Grant (born October 8, 1936) are a British married couple who are evolutionary biologists at Princeton University. Each currently holds the position of emeritus professor. They are known for their work with Darwin's finches on Daphne Major, one of the Galápagos Islands. Since 1973, the Grants have spent six months of every year capturing, tagging, and taking blood samples from finches on the island. They have worked to show that natural selection can be seen within a single lifetime, or even within a couple of years. Charles Darwin originally thought that natural selection was a long, drawn out process but the Grants have shown that these changes in populations can happen very quickly.
https://en.wikipedia.org/wiki?curid=584186
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Naval School Explosive Ordnance Disposal (NAVSCOLEOD), a Navy-managed command, jointly staffed by Army, Navy, Air Force, and Marine Corps personnel, had its official ribbon cutting on a new consolidated training facility in April 1999. These five new buildings, which centralize all basic EOD training at Eglin, total and were built at a cost of $16.2 million. NAVSCOLEOD’s additional facilities are located just inside the east gate, including a three building, 252 room bachelor quarters complex, a second training facility located in Building 845, and an extensive practical training facility on Range D-51. Three demolition training areas at Ranges D-51 and C-52 West, and C-52 North, a training aid and facilities maintenance compound and six explosive storage magazines are also part of the school’s facilities.
https://en.wikipedia.org/wiki?curid=33714574
1,800,976
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Tufts OCW could be considered within the broader context of the open educational resources (OER) movement. OER can include open content, tools, or infrastructure. Tufts has been engaging in OER work for more than a decade, with the majority of efforts related to the development of the Tufts University Sciences Knowledgebase (TUSK). TUSK is an integrated digital repository and curriculum knowledge management and delivery system used by Tufts' health sciences schools and programs, and health sciences institutions in India, Tanzania, Uganda, Kenya, and the United States. TUSK's use of the National Library of Medicine's Unified Medical Language System (UMLS) as the controlled vocabulary for its content management (metadata, searching, etc.) enables the creation and delivery of integrated, developmental curricula by individuals or teams of faculty across the health sciences.
https://en.wikipedia.org/wiki?curid=19425510
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A WSN is built of "nodes" – from a few to hundreds or thousands, where each node is connected to other sensors. Each such node typically has several parts: a radio transceiver with an internal antenna or connection to an external antenna, a microcontroller, an electronic circuit for interfacing with the sensors and an energy source, usually a battery or an embedded form of energy harvesting. A sensor node might vary in size from a shoebox to (theoretically) a grain of dust, although microscopic dimensions have yet to be realized. Sensor node cost is similarly variable, ranging from a few to hundreds of dollars, depending on node sophistication. Size and cost constraints constrain resources such as energy, memory, computational speed and communications bandwidth. The topology of a WSN can vary from a simple star network to an advanced multi-hop wireless mesh network. Propagation can employ routing or flooding.
https://en.wikipedia.org/wiki?curid=1076662
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With species being named as part of "Pterygotus" becoming increasingly diverse, researchers began to name subgenera, such as "Pterygotus" ("Erettopterus"), named by John William Salter in 1859 for species of "Pterygotus" with a bilobed telson, such as "P. osiliensis". The family Pterygotidae would be erected by Clarke & Ruedemann in 1912, and new subgenera were named for "Pterygotus" by Ruedemann in 1935. These subgenera included "Pterygotus" ("Curviramus") and "Pterygotus" ("Acutiramus") and were differentiated from other "Pterygotus" by the curvature of the denticles (teeth) of the chelicerae. The name ""Acutiramus"" derives from Latin "acuto" ("acute" or "sharp") and Latin "ramus" ("branch"), referring to the acute angle of the final tooth of the claws relative to the rest of the claw. The species originally included in the subgenus were "P." ("A.") "bohemicus", "P." ("A.") "buffaloensis" and "P." ("A.") "macrophthalmus." "P. buffaloensis" was designated as the type species of the subgenus "Acutiramus". Adhering to the rule of nomenclatural priority, the earliest used name should have priority. This was pointed out by Erik N. Kjellesvig-Waering in a 1955 publication, stating that using "P. buffaloensis" over "P. cummingsi" was "subjective" and in 1961, Kjellesvig-Waering recognised "P. cummingsi" as the name of the type species. "Acutiramus" continued to be treated as a subgenus of "Pterygotus" until it was raised to the level of a separate genus by Leif Størmer in 1974.
https://en.wikipedia.org/wiki?curid=14195347
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NASA maintains a catalog of Venus transits covering the period 2000 BC to 4000 AD. Currently, transits occur only in June or December (see table) and the occurrence of these events slowly drifts, becoming later in the year by about two days every 243-year cycle. Transits usually occur in pairs, on nearly the same date eight years apart. This is because the length of eight Earth years is almost the same as 13 years on Venus, so every eight years the planets are in roughly the same relative positions. This approximate conjunction usually results in a pair of transits, but it is not precise enough to produce a triplet, since Venus arrives 22 hours earlier each time. The last transit not to be part of a pair was in 1396. The next will be in 3089; in 2854 (the second of the 2846/2854 pair), although Venus will just miss the Sun as seen from the Earth's equator, a partial transit will be visible from some parts of the southern hemisphere.
https://en.wikipedia.org/wiki?curid=632331
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The test of Kiwi B1A, the last test to use gaseous hydrogen instead of liquid, was initially scheduled for 7 November 1961. On the morning of the test, a leaking valve resulted in a violent hydrogen explosion that blew out the walls of the shed and injured several workers; many suffered ruptured eardrums, and one fractured a heel bone. The reactor was undamaged, but there was extensive damage to the test car and the instrumentation, resulting in the test being postponed for a month. A second attempt on 6 December was aborted when it was discovered that many of the diagnostic thermocouples had been installed backward. Finally, on 7 December, the test got under way. It was intended to run the engine at 270 MW for 300 seconds, but the test was scrammed after only 36 seconds at 225 MW because hydrogen fires started to appear. All the thermocouples performed correctly, so a great deal of useful data was obtained. The average hydrogen mass flow during the full power portion of the experiment was .
https://en.wikipedia.org/wiki?curid=23821416
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Modern GPS receivers work somewhat similarly in that they also correlate a received PN bit stream (at 1.023 Mbit/s) with a local reference to measure distance. But GPS is a receive-only system that uses relative timing measurements from a set of satellites to determine receiver position while the Apollo USB is a two-way system that can only determine the instantaneous distance and relative velocity. However, an orbit determination program can find the unique spacecraft state vector from range, range-rate (relative velocity) and antenna look angle observations made by one or more ground stations assuming purely ballistic spacecraft motion over the observation interval.
https://en.wikipedia.org/wiki?curid=26270139
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In 2009, the same Korean researchers published a further study on the anti-obesity and anti-diabetic effects of DOM in obese mice. The control group received tap water and the experimental group received DOM of hardness 1000 for 84 days. The DOM-fed group compared to the control group reported a 7% body weight decrease, reduced plasma glucose levels by 35.4%, and a significant increase in glucose disposal after 84 days. The research suggests that the anti-diabetic and anti-obesity activities of DOM were mediated by modulating the expression of diabetes and obesity-specific molecules. Taken together, these results provide a possibility that continuous intake of DOM can be of dietary therapeutic value for the treatment of obesity and diabetes. In 2013, further diabetes-induced mice study was conducted to establish dosage regimes. The researchers concluded that DOM provided a novel activator for glucose uptake.
https://en.wikipedia.org/wiki?curid=46377168
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Ohio State operates North America's 18th-largest university research library with a combined collection of over 5.8 million volumes. Additionally, the libraries regularly receive about 35,000 serial titles. Its recent acquisitions were 16th among university research libraries in North America. Along with 21 libraries on its Columbus campus, the university has eight branches at off-campus research facilities and regional campuses, and a book storage depository near campus. In all, the Ohio State library system encompasses 55 branches and specialty collections. Some more significant collections include the Byrd Polar Research Center Archival Program, which has the archives of Admiral Richard E. Byrd and other polar research materials; the Hilandar Research Library, which has the world's largest collection of medieval Slavic manuscripts on microform; the Ohio State Cartoon Library & Museum, the world's largest repository of original cartoons; the Lawrence and Lee Theatre Research Institute; and the archives of Senator John Glenn.
https://en.wikipedia.org/wiki?curid=22217
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In May 2011, the National Highway Traffic Safety Administration (NHTSA) and EPA issued a joint final rule establishing new requirements for a fuel economy and environment label that is mandatory for all new passenger cars and trucks starting with model year 2013. The ruling includes new labels for alternative fuel and alternative propulsion vehicles available in the US market, such as plug-in hybrids, electric vehicles, flexible-fuel vehicles, hydrogen fuel cell vehicle, and natural gas vehicles. The common fuel economy metric adopted to allow the comparison of alternative fuel and advanced technology vehicles with conventional internal combustion engine vehicles is miles per gallon of gasoline equivalent (MPGe). A gallon of gasoline equivalent means the number of kilowatt hours of electricity, cubic feet of compressed natural gas (CNG), or kilograms of hydrogen that is equal to the energy in a gallon of gasoline.
https://en.wikipedia.org/wiki?curid=20549371
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The university is accredited by the Southern Association of Colleges and Schools (SACS). It is the third largest Florida university by student population, and is the fifth largest single-campus university in the United States with 57,841 students enrolled for during the 2020–21 school year. The University of Florida is home to 16 academic colleges and more than 150 research centers and institutes. It offers multiple graduate professional programs—including business administration, engineering, law, dentistry, medicine, pharmacy and veterinary medicine—on one contiguous campus, and administers 123 master's degree programs and 76 doctoral degree programs in eighty-seven schools and departments. The university's seal is also the seal of the state of Florida, which is on the state flag, though in blue rather than multiple colors.
https://en.wikipedia.org/wiki?curid=60611
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Key challenges of such an architecture are network latency and performance—a graphically intensive application (as most are when presented using a GUI) being served over a slow or bandwidth-restricted network connection requires considerable compression and optimization to render the application usable by the client. The client machine may be a different platform, and may not have the same GUI routines available locally—in this case the server may need to send the actual bitmap data over the connection. Depending on the client's capabilities, servers may also off-load part of the graphical processing to the client, e.g. to render multimedia content. ICA runs natively over TCP port 1494 or may be encapsulated in Common Gateway Protocol (CGP) on TCP 2598. ICA supports the concept of channels at a session layer to encapsulate rich media redirection or USB extension within ICA.
https://en.wikipedia.org/wiki?curid=309961
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Calculations as well as empirical observations have demonstrated that perovskite nanocrystals are defect-tolerant semiconductor materials. As a result, they do not require epitaxial shelling or surface passivation since they are insensitive to surface defect states. In general, the perovskite nanocrystal surface is considered to be both ionic and highly dynamic. Initial reports utilized dynamically bound oleylammonium and oleate ligands that exhibited an equilibrium between bound and unbound states. This resulted in severe instability with respect to purification and washing, which was improved in 2018 with the introduction of zwitterionic ligands. The stability and quality of these colloidal materials was further improved in 2019 when it was demonstrated that deep traps could be generated by the partial destruction of the lead-halide octahedra, and that they could also be subsequently repaired to restore the quantum yield of nanocrystals.
https://en.wikipedia.org/wiki?curid=61491450
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After 1996, adaptive hypermedia grew rapidly. Research teams commenced projects in adaptive hypermedia, and many students selected the subject area for their PhD theses. A book on adaptive hypermedia, and a special issue of the New Review of Hypermedia and Multimedia (1998) were published. Two main factors accounted for this growth. Due a diverse audience, the internet boosted research into adaptivity. Almost all the papers published before 1996 describe classic pre-Web hypertext and hypermedia; the majority of papers published since 1996 are devoted to Web-based adaptive hypermedia systems. The second factor was is the accumulation and consolidation of research experience in the field. Early papers provided few references to similar work in adaptive hypermedia, and described original laboratory systems developed to demonstrate and explore innovative ideas. After 1996, papers cite earlier work, and usually suggest either real world systems, or research systems developed for real world settings by elaborating or an extending techniques suggested earlier. This is indicative of the relative maturity of adaptive hypermedia as a research direction.
https://en.wikipedia.org/wiki?curid=9269429
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On the map the player can direct divisions or groups of divisions. Fighting starts when an army starts moving into a defended enemy territory. The invading units do not have to be inside enemy territory to attack. A province is immediately occupied when the invaders arrive there with no opposition left. Because of this, a player can blitz through large swaths of enemy lands with minimal micromanagement. In addition, units who move constantly lose organization and risk losing supply, so poorly executed attempts to blitzkrieg can be stopped. Provinces can be fortified and infrastructure increased to improve combat performance. Structures include radar, and static AA. Many fortifications are pre-built, such as the Maginot Line along the French-German border.
https://en.wikipedia.org/wiki?curid=1327973
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In the past, military and police faced with undesirable escalation of conflict had few acceptable options. Military personnel guarding embassies often found themselves restricted to carrying unloaded weapons. National guards or policing forces charged with quelling riots were able to use only batons or similar club-like weapons, or bayonet or sword charges, or fire live ammunition at crowds. In the late 1980s and early 1990s, the Non-lethality Policy Review Group at U.S. Global Strategy Council in Washington and other independent think tanks around the world called for a concerted effort to develop weapons that were more life-conserving, environmentally friendly, and fiscally responsible than weapons available at that time. The U.S. Congress and other governments agreed and began an organized development of non-lethal weapons to provide a range of options between talking and shooting.
https://en.wikipedia.org/wiki?curid=146808
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There are many applications for AMS throughout a variety of disciplines. AMS is most often employed to determine the concentration of C, e.g. by archaeologists for radiocarbon dating. Compared to other radiocarbon dating methods, AMS requires smaller sample sizes (about 50 mg), while yielding extensive chronologies. MS technology has expanded the scope of radiocarbon dating. Samples ranging from 50,000 years old to 100 years old can be successfully dated through utilizing AMS. An accelerator mass spectrometer is required over other forms of mass spectrometry due to their insufficient suppression of molecular isobars to resolve CH and CH from radiocarbon. Because of the long half-life of C decay counting requires significantly larger samples. Be, Al, and Cl are used for surface exposure dating in geology. H, C, Cl, and I are used as hydrological tracers.
https://en.wikipedia.org/wiki?curid=1127875
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