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Username or Email Address Bow, Heart, Rectangle, Oval flower, Star, Shell, Double heart There are no reviews yet. Your email address will not be published. Required fields are marked * Your review * Save my name, email, and website in this browser for the next time I comment.
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Panel Management Careers – Increase Your Périmètre and Enhance your Leadership Skills Board managing jobs are an easy way to broaden your professional horizons, strengthen your leadership expertise and build your reputation. Getting involved with a plank of directors can help you gain new perspectives and hone the expertise in areas like financial control, business technique or long-term sustainability. A growing board is a main component of successful organizations and nonprofits. That they rely on a synergistic blend diverse specialist experiences, age ranges best deals on unlimited data plans and economic qualification to help them serve their organizations more effectively. The role of any board should be to provide tactical guidance and oversight to the organization, even though the CEO performs to execute in those approaches. The panel helps to slowly move the CEO when it comes to organizational assets, performance analysis, course funding and policy creation. As a aboard member, you are expected to know the organization’s quest, vision and values, and also its governance structure. Your job is usually to help the CEO make decisions that are right for the organization based upon those central principles, whilst also assisting to manage hazards. During a board meeting, you are expected to inquire questions and difficult task assumptions. You must keep your focus on the long term, nevertheless, you should continue to take action the moment issues occur that have an important effect on the organization. The ability to talk to stakeholders and also other board subscribers is improved when you have a very good comprehension of their assignments and beliefs. You should also be aware of the company’s culture and values and just how they are shown in its do the job practices, processes and systems.
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Welcome to forum.xnxx.com, the ultimate destination for serious discussions about everything related to sex. Whether you’re a curious novice or a seasoned enthusiast, this forum serves as an invaluable resource where you can freely ask for tips, advice, and engage in meaningful conversations with like-minded individuals from around the globe.At forum.xnxx.com, we recognize that sex is an integral part of human nature, and fostering healthy dialogue that encourages education, understanding, and exploration is our primary goal. This SEO-friendly platform isn’t just another adult site; it’s a virtual community where individuals can come together to share experiences, seek guidance, and learn from one another’s diverse perspectives. When it comes to discussing sex seriously, authenticity and respect are paramount. Our forum is meticulously designed to provide a safe space where people feel comfortable expressing their thoughts openly while maintaining complete anonymity if desired. We firmly believe that everyone has something unique to contribute, which contributes to a rich tapestry of knowledge within our vibrant community. If you’re new to the world of sexual exploration, fear not! At forum.xnxx.com, we have experienced members who are eager to support your journey. From basic questions about anatomy and contraception to more complex inquiries regarding alternative lifestyles or fetishism – no topic is off-limits here. Rest assured that our dedicated users are ready to offer well-informed advice based on their personal experiences or extensive research. What sets forum.xnxx.com apart from other platforms is its emphasis on staying abreast of evolving sexual health and wellness trends. Sexual education is an ongoing process, and we understand the importance of keeping up with changing information. Our knowledgeable members provide innovative insights into topics such as consent culture, LGBTQ+ inclusivity, self-care techniques, and mental health aspects of sexuality. Engaging in these discussions will not only enhance your understanding but also expand your horizons beyond traditional notions of pleasure. As an SEO-friendly description writing requirement, we understand the significance of optimizing search engine visibility while delivering compelling content. Therefore, we ensure that forum.xnxx.com employs best practices to drive organic traffic, enabling individuals like yourself to discover our invaluable resources effortlessly. We actively embrace user feedback and continually refine our platform, applying the latest SEO strategies to enhance your browsing experience. In addition to questions and advice-seeking threads, our community thrives on sharing personal stories that foster empathy and understanding among members. By shedding light on their own trials and triumphs, users inspire others to embark on their unique sexual journeys with confidence. From overcoming insecurities to celebrating sexual liberation, these narratives showcase the power of unity and encourage exploration without judgment. To further augment the educational value of forum.xnxx.com, we offer a diverse range of content beyond just discussions. Our blog section features informative articles written by industry experts covering everything from sexual wellness tips to debunking common myths. Additionally, engaging podcasts explore various dimensions of sexuality through thought-provoking discussions with renowned professionals in the field. With regular updates across all media channels, there will always be something fresh and exciting for you to discover. Rest assured that forum.xnxx.com adheres stringently to legal guidelines and enforces strict moderation policies to create a respectful environment for all users. We prioritize everyone’s safety by prohibiting any explicit content or non-consensual discussions that may compromise our core principles. So why wait? Join the global network of open-minded individuals at forum.xnxx.com today, and embark on an enriching journey towards expanding your knowledge about sex while connecting with others who share similar passions in an inclusive space where serious discussions reign supreme!
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Hundred Waters are a band that have really grown on me over time. I enjoyed their first album but I think I approached it from the wrong mindset from what it offered, and then found their follow-up album channelled ethereal electronica into something you’d dance to underground. “Communicating” continues that push towards something dance worthy but at its very heart, it’s really a musical ear caress of gentile synths, voices and rhythms that’s as introvert as it is extrovert. “Particle” opens strongly with power chords, warped synths and catchy riffs. It’s as dance floor as the band get and euphoric too. The think bendy bass, wordy lyrics and heavy beats really push through to make something radio friendly. “Wave to Anchor” follows the trend with another would be hit. It’s bright synths, happy piano riffs and vocal collages create a mermaid like sirens call. The gem in Hundred Waters is Nicole Miglis’ smooth vocals across a variety of registers and they are on fire here. After two party stonkers “Prison Guard” is a darker, hushed track. It’s militant drum roll is kept quiet in the background of the mix, rustling along but providing intensity behind the washes of synths and voices that weave a story of intrigue. “Parade” is a bluesy ballad that strips everything back – aside from the production on Nicole’s voice. It makes her sound like she’s singing in a cave and whilst it usually suits the electronica songs, this is almost entirely acoustic based and so it sounds a bit strange. “At Home & In My Head” returns us to the dance floor but take us towards the more aggressive synth sound that surrounded the second half of their album “The Moon Rang Like A Bell”. I think this borrowing of rock tropes really works well for the band, and there’s a hint of GoGo Penguin in there too. “Firelight” in contrast is a beautifully warm gospel like vocal piece. Nicole’s voice is layered like a choir whereas the R n B beats and minimal spacious synths support the lullaby dream vibe. It’ll be an underrated track among the many gems here, but seek it out. After the short mood piece “Re” we have the creepy but alluring “Fingers”. It’s twisted melodic bells, downward sloping chords and chunky drums over despondent lyrics make the track feel grande, inspired and emotive. It works perfectly for the title track to slink in. It’s a simple minor chord pattern with “are we communicating” being sung on loop under a heavily vocodered main vocal line. Each part of the song gets more and more dramatic over time with guitar feedback and added noises filtering in – its possibly my favourite track on the album and is utterly amazing. It bleeds into the cathartic “Blanket Me” which has more in common with an epic action movie soundtrack than dream pop as things go very post-rock – and again it is amazing. Much like how Daughter can make those tracks that boil up to an explosion of pure emotion – Hundred Waters achieve it here with this arc of songs. It closes off with the dream like “Better” with hazy guitars, bluesy chords and an extended distant outro that makes you feel like you’re saying goodbye before jetting off to another planet. Whilst not moving too far away from their signature sound, Hundred Waters perform very successful tests of post-dream pop and dance floor fillers here. I suspect some people may have a preference for either end of the scale, but the album is utterly beautifully and will inspire you to dream. Recommended Track : Wave to Anchor
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Everest base camp or Annapurna base camp? It’s the decision every trekker has to make eventually before coming to Nepal. Trek to the base camp of the world’s highest mountain or trek to the sanctuary of gods? Both are the world’s greatest treks and most travellers end up trekking both in the end. Annapurna Base Camp Table of Contents The gateway to the Everest region is Tenzing Hillary Airport, Lukla. It takes 40-45 mins of spectacular flight from Kathmandu airport to reach Lukla 2,800m/9187ft. During the peak season, there are more than 35 flights in one day. Grab a seat on the left side of the plane from Kathmandu to Lukla and the right side from Lukla to Kathmandu for views of the Himalayas from your seat. However, if you prefer a classic route and want to avoid the flight then you can drive to Jiri or Phaplu and start your Everest Base Camp Trek. The starting point of Annapurna is Pokhara, the city of lakes situated 200 km SW of Kathmandu. To reach Pokhara, you can take either a 15-20 mins flight or a 6-7 hrs drive from Kathmandu. There are daily tourist buses departing for Pokhara from Kathmandu. Pokhara is also an ideal place to chill and is a hub for outdoor activities (Paragliding, Zip flyer, Rafting, Bungy Jump, Mt. Biking) Everest region offers massive views of mountains all the way. If you want to be immersed in the mountains, then this is your place. Besides Mt. Everest, you will get views of Lhotse (the 4th highest mountain in the world), Nuptse, Ama Dablam, Thamserku, etc. From Kalapathar you can get panoramic views of the highest mountains in the world. This trip takes you through Sherpa land reaching amazing high-altitude scenery: the great monastery at Thyangboche, views of Ama Dablam, Everest and other grand Himalayan peaks Annapurna offers much variety of scenery as compared with Everest with high mountains, low fertile lands, Petite thatched roofed villages, and Rhododendron forest. A great trek into Himalayan journeys of a unique kind as you enter into the inner chambers of the legendary Annapurnas. Hereabouts, massive mountains such as Annapurna 1, Annapurna South, Gangapurna and Machhapuchhre, surround the original geographic amphitheatre known as the Sanctuary of the Annapurna, a feast for the eyes that beholds nature at its zenith. Everest Base Camp The Everest base camp trek requires at least 14 days to complete, including international arrival and departure. The trek starts at an elevation of 2800m at Lukla and reaches up to an elevation of 5364m at the base camp. You will need to keep at least 2 acclimatization days at Namche and Dingboche for better chances of reaching the base camp. Many do the trek in 17 days itinerary keeping at least 1 free day in Kathmandu. Keeping one free day in Kathmandu is highly recommended as the Lukla flights are often delayed and cancelled due to poor weather. Annapurna Base Camp Annapurna base camp trek can be done in 10 days with international arrival and departure included. The trek reaches up to an elevation of 4130m and starts from Pokhara. The approach to Pokhara and the trek starting point are accessible by both air and land. The chances of Pokhara flights being cancelled are very slim as compared to Lukla. However, delays are frequent and we recommend staying a night in Pokhara before the trek. A standard itinerary of Annapurna base camp will be of 12 days keeping a free day in Kathmandu after the trek. Trekking to Everest Base Camp is physically strenuous in terms of its high altitude. The maximum altitude is 5,545m/18,193ft at Kalapathar and you will need to sleep at a higher altitude at Gorekshep 5,140m/16,865ft. You will reach the elevation of 3,450m/11,319ft on Day 2 of the trek so make sure your itinerary is devised well-keeping plenty of rest and acclimatization. Trek to Everest Base Camp involves daily trekking of approximately 7 – 8 hours along rocky ridges of high Himalayan peaks. Trekking in Everest doesn’t require previous experience but one should be moderately fit and have the ability to enjoy walking and adapting to high altitude conditions Moderate to fairly challenging. The trail is not difficult in a way that would tire your limbs. You’d enjoy the trip because you will be trampling through numerous pretty villages along the way. Annapurna is also less touristy and crowded than Everest. Maximum altitude is 4130m/13550ft at Annapurna Base Camp and on a daily basis, you can expect to be walking for about 5 – 6 hours. The perfect setting for an introduction to moderate & challenging trekking in Nepal. Activity level is fairly easy but does expect ups and downs as well for there will be hills to climb as well and the well-known ‘Nepali flat’ – a little bit up and a little bit down. People and Culture Sherpas live in the upper regions of Solu Khumbu. They emigrated from Tibet about 600 years ago. The Khumbu/Everest region has provided a strong group of able-bodied, hardy and fearless Sherpa guides. Sherpas practise Tibetan Buddhism, which is also known as Lama Buddhism. The most prominent ethnic groups in the Annapurna region are the Gurung and Thakali. The famous Gurkha Soldiers hail from this region and most likely you will get to walk through their villages. Both treks have their own unique experiences and they both deserve to be included in a list of the world’s greatest treks. If you are looking for a more adventurous trip into the high altitude, then Everest is your place but if you are looking for a moderate and diverse trip then head to Annapurna. If you got time and energy we’d highly recommend visiting both regions.
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Kalamata is aprox. 3hrs away from Athens. You can reach Kalamata from Athens by Bus or car. See the Bus schedule Ktel Messinia and you can find all the information you need about how to get to Kalamata. For the bus schedule from Kalamata to the Art Farm check our website or give us a call. We suggest, you rent a car for a convenient transportation. If you don't have a car we can arrange transfers from and to the Kalamata airport or bus station for an extra fee.
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ʻoiai/ ʻoi.ai / - ʻOiai au i ke kula, while I was at school. - ʻOiai i ke au o Kamehameha, during the time of Kamehameha. - Gram. 11.1. 2. conjunction, Although. - Ua hōʻeha ʻoia ʻoiai nō ʻaʻohe ona lima, he was hurt, but not his hands. Papa helu loli | Wehewehe Wikiwiki update log
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Best book for kvs pgt computer science Best book for kvs pgt computer science. All of you know about computer science that there will be a huge increase in the use of computer in the coming time, seeing this, friends have started taking computer science as a subject. Computer science subject is a very interesting subject and in this computer All the information related to is given. Just a few days ago, a lot of vacancies of computer science came out and this time Kendriya Vidyalaya has also announced these vacancies. So friends, for your information, let us tell you about Computer Science Post Graduate Teacher in Kendriya Vidyalaya. Recruitment has been done in which you must have post graduation with computer science to apply, if you have post graduation with computer science then you can apply for this recruitment. Kvs pgt computer science best book for preparation. After applying you have to prepare well and To prepare well, you should have such books from which you do not have to do anything else after preparing, so friends, looking at your problem today, we have brought some such books which will help you in preparing for it. Today we will tell you the best book for KVS PGT Computer Science, Yes friends, which are the best books for Kendriya Vidyalaya PGT Computer Science, we will give this information in detail in our article till the end keep at it. Today’s important questions - Which book is best for kvs pgt computer science? - best book for kvs pgt computer science preparation? - kvs ke liye best pgt computer science book ? Friends, the following five books are such books which are very famous for computer science, these books are of post-graduation level and probably you will know that in all the vacancies which have been taken out in Kendriya Vidyalaya, all these questions will come in the exam. Will come from the books, my advice to you is that you should buy these five books and prepare from them, but if you cannot buy all the five books, then buy one or two of these books and read them thoroughly so that the coming You can easily pass the S PGT Computer Science exam, see the books given below. Click below for purchase best pgt computer science book Friends, the above given five books will be busy for you because you are about to take the KVS PGT Computer Science exam. These five books are the books which have been sorted out from all the computer science books in India. First book is VS and NVS PGT Computer Science this is the book which is made for both VS and NVS college and it has computer science of post graduate level next book is TGT and PGT computer science friends in it trend graduate teacher and Post graduate teacher has been told about computer science of both, which level of computer science comes in both is in this book. Friends next book KVS PGT computer science this book is special for Kendriya Vidyalaya post graduate teacher computer science only It has been made if you can not buy all the books, then definitely buy this book, it is very useful, friends, the assurance of the. Next book is also made for both the Post Graduate Teacher Computer Science and the next book is only for PGT Computer If it is computer science, then my advice is that these five books are best for you, if you prepare with their prices, then you will be able to pass the Kendriya Vidyalaya PGT Computer Science exam easily. Thanks for read us.
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Table of Contents In the annals of history, there are battles that resonate with the spirit of freedom and rebellion. The Battle of Goliad, which took place on October 9, 1835, stands as a testament to the Texian rebels’ unwavering determination in their fight against Mexican rule. This pivotal clash marked a crucial turning point in the Texas Revolution, as it saw the Texians seize control of Goliad’s supplies, crippling the Mexican forces and bolstering their own cause. Motivated by a desire for independence and driven by strategic considerations, the Texian rebels devised a plan to disrupt Mexican troop movements and defenses. Led by George Collingsworth and Benjamin Milam, they launched a daring attack on Presidio La Bahía, successfully capturing this key stronghold. With Goliad now under Texian control, they were able to consolidate their position and further challenge Mexican authority. The aftermath of the Battle of Goliad ignited swift Mexican counterattacks but also served as an inspiration for future battles in the Texas Revolution. Its significance lies not only in its immediate impact on military operations but also in its enduring legacy as a symbol of defiance and resistance against oppression. As we delve into the details and chronology of this battle, it becomes evident that its historical importance transcends mere military strategy or territorial gains. The Battle of Goliad embodies the unyielding spirit of those who yearned for freedom, serving as a reminder that when faced with tyranny, ordinary men can rise up to achieve extraordinary feats. - The Battle of Goliad took place on October 9, 1835, and was a significant event in the Texas Revolution. - Texian rebels led by George Collingsworth and Benjamin Milam launched a surprise attack on Presidio La Bahía in Goliad, seizing control of valuable supplies and weakening Mexican forces. - The capture of Goliad’s supplies gave Texian forces an advantage over the Mexican forces and boosted morale among Texian troops. - The Battle of Goliad set into motion events that would determine Texas’ fate in its struggle for independence and played a pivotal role in the fight for freedom. The Texas Revolution: Background and Context The Texas Revolution, a pivotal event in American history, was fueled by political tensions and aspirations for independence from Mexico. In the early 19th century, Anglo-American settlers began to migrate to Mexican-controlled Texas, attracted by cheap land and economic opportunities. However, clashes soon erupted between these settlers and the Mexican government over issues such as immigration restrictions and cultural differences. The Mexican government’s efforts to centralize power and curb local autonomy further intensified these tensions. The Texian rebels, as they came to be known, were motivated by a desire for self-governance and the preservation of their rights under the Mexican Constitution of 1824. They believed that the policies of President Antonio López de Santa Anna disregarded these constitutional guarantees. As dissatisfaction grew among the Texian population, rebel leaders devised strategies to achieve their objectives. Transitioning into the subsequent section about ‘the Texian rebels’ motives and strategies,’ it becomes evident that their determination to secure independence led them down a path of military confrontation with the Mexican government. The Texian Rebels’ Motives and Strategies Motivated by their desire for independence, the Texian rebels employed strategic tactics in their mission to secure vital resources. The motives of the Texian rebels were deeply rooted in their aspiration for freedom and autonomy from Mexican rule. They recognized that control over key supplies was crucial for maintaining a sustained resistance against the Mexican forces. Thus, they strategically targeted locations like Goliad, which housed significant military provisions. The rebels devised various strategies to achieve their objectives. One such strategy involved seizing control of strategic points and cutting off supply lines to weaken the Mexican army’s ability to wage war effectively. By capturing Goliad, the Texians not only acquired essential armaments but also dealt a substantial blow to Mexico’s military capabilities. Additionally, the Texian rebels sought support from sympathetic individuals within Mexico who shared similar sentiments about independence. This diplomatic approach aimed to garner both moral and material assistance from those who opposed centralized authority. Transitioning into the subsequent section about ‘Mexican troop movements and defenses,’ it is essential to examine how these rebel strategies affected and shaped the actions of the Mexican forces on a broader scale. Mexican Troop Movements and Defenses Transitioning into an analysis of Mexican troop movements and defenses, it is pertinent to explore the strategic implications of the Texian rebels’ actions on a broader scale. Understanding the Mexican troop movements and Goliad’s defenses sheds light on the challenges faced by both sides in this conflict. - Mexican Troop Movements: The Mexican army had stationed troops at Presidio La Bahia in Goliad, recognizing its strategic importance as a key supply depot for their forces. However, due to their focus on suppressing rebellion in other regions, they did not anticipate an attack on Goliad itself. This lack of anticipation resulted in inadequate defensive preparations. - Goliad’s Defenses: In terms of fortifications, Goliad boasted sturdy stone walls surrounding Presidio La Bahia. Additionally, they had artillery pieces positioned strategically to defend against potential attacks. However, these defenses were not optimized for a full-scale assault from within the town itself. Examining Mexican troop movements and Goliad’s defenses reveals how the Texian rebels exploited weaknesses in these areas to gain an advantage over their opponents. With supplies secured and strongholds established elsewhere, they set the stage for what would be known as the opening shots: Collingsworth and Milam’s attack. The Opening Shots: Collingsworth and Milam’s Attack Launching a surprise assault on Goliad, the rebels led by Collingsworth and Milam initiated their offensive with audacity and agility. The duo devised a strategic plan that aimed to exploit the element of surprise, catching the Mexican forces off guard. As part of their strategy, they carefully studied the movements and defenses of the Mexican troops stationed in Goliad. They identified weaknesses in their opponent’s positions, such as gaps in surveillance and lack of preparedness for an attack from within the town. On October 9, 1835, Collingsworth and Milam executed their meticulously planned surprise attack. Under cover of darkness, rebel forces swiftly moved into position while avoiding detection from Mexican sentries. At dawn, they launched a coordinated assault on the unsuspecting defenders. The element of surprise played a crucial role in tipping the scales in favor of the rebels during this initial engagement. With their opening shots fired successfully, Collingsworth and Milam set into motion a series of events that would ultimately lead to the capture of Presidio La Bahía. Transitioning seamlessly into this subsequent section about ‘the capture of Presidio La Bahía,’ it becomes evident that their audacious tactics had set them on a path towards achieving one step closer to victory over Mexican forces in Goliad. The Capture of Presidio La Bahía Having successfully executed their surprise attack on Goliad, Collingsworth and Milam’s forces swiftly moved forward to capture Presidio La Bahía, marking a significant step towards their ultimate goal of victory over the Mexican forces. This strategic move required careful planning and precise execution to overcome the military defenses in place at the Presidio. To capture Presidio La Bahía, Collingsworth and Milam employed various effective strategies. They assessed the strengths and weaknesses of the Mexican defenders, identifying potential vulnerabilities. Utilizing their knowledge of military tactics, they devised a plan that exploited these weaknesses while minimizing casualties among their own troops. Through coordinated movements and strategic positioning, they were able to gain control over the Presidio’s perimeter. The following table summarizes some key aspects of Collingsworth and Milam’s capture strategies: |Capture Strategies||Military Defenses Overcome| |Assessing vulnerabilities||Identifying weak points in defense| |Coordinated movements||Outmaneuvering defenders| |Strategic positioning||Neutralizing strongholds| By capturing Presidio La Bahía, Collingsworth and Milam secured an important stronghold that provided them with a base for further operations against the Mexican forces. This successful advance allowed them to focus on securing Goliad’s valuable supplies without delay. Transition: With Presidio La Bahía under their control, Collingsworth and Milam now turned their attention towards securing Goliad’s valuable supplies… Securing Goliad’s Valuable Supplies After the successful capture of Presidio La Bahía by Texian forces led by George Collingsworth and Benjamin Milam, attention turned to securing the valuable supplies housed in Goliad. Goliad held strategic importance due to its location and the resources it possessed. The town was home to a large quantity of munitions, including cannons, muskets, powder, and shot. Additionally, there were ample provisions such as food, clothing, and medical supplies that could sustain an army in battle. Recognizing the significance of Goliad’s resources in their fight for independence from Mexico, Texian leaders wasted no time in establishing control over these supplies. By doing so, they ensured that they would have access to crucial weaponry and provisions necessary for future military campaigns. The importance of Goliad’s resources cannot be overstated. With these supplies under Texian control, they gained a significant advantage over the Mexican forces. Moreover, securing these vital resources allowed them to consolidate their power and strengthen their position within the region. With Goliad firmly in Texian hands and its valuable supplies secured, the stage was set for further Texian control and consolidation of their newly acquired territories without delay or hesitation. Texian Control and Consolidation Texian control and consolidation of their newly acquired territories were crucial in solidifying their position and establishing a foundation for future endeavors. After seizing Goliad’s valuable supplies, the Texians recognized the importance of maintaining control and unity over the region. This enabled them to effectively organize their forces and establish a stronghold to serve as a base for further operations. The Texians focused on consolidating their power by fortifying strategic locations within Goliad and its surrounding areas. This allowed them to control key supply routes, ensuring their troops were adequately provisioned. In addition to military measures, the Texians also worked towards achieving political unity among themselves. They formed committees and established local governments to promote cooperation and coordination among different factions, fostering a sense of common purpose. Texian leaders recognized Goliad’s significance as an important logistical hub. Its location along the coastal plain provided access to vital resources and transportation routes, making it essential for sustaining their operations. Texian consolidation efforts not only secured Goliad but also laid the groundwork for future expansion into other Mexican-controlled territories. However, this growing threat did not go unnoticed by Mexico, leading to subsequent counterattacks in an attempt to regain control over these regions. Mexican Response and Counterattacks Despite Texian efforts to consolidate their control over Goliad and its surrounding territories, Mexico was quick to respond and launched counterattacks in an attempt to regain authority over the region. Mexican retaliation against Texian forces included several key actions aimed at weakening Texian defenses and reestablishing Mexican control: - Recapturing Presidio La Bahía: On October 9, 1835, Mexican General Cos led a force of approximately 400 soldiers in an assault on Presidio La Bahía. Despite initial resistance from Texian defenders, the outnumbered Texians were eventually overwhelmed, resulting in the recapture of the presidio by Mexican forces. - Mexican Reinforcements: Following the recapture of Presidio La Bahía, Mexico dispatched additional troops to reinforce their presence in Goliad. These reinforcements further bolstered Mexican military capabilities and put pressure on the embattled Texians. - Siege of Goliad: In response to increasing Mexican aggression, Texian commander George Collingsworth ordered his men to fortify Goliad’s defenses. However, these measures proved inadequate as Mexican forces laid siege to Goliad, effectively cutting off supply lines and isolating the Texians within the town. The Mexican response and subsequent counterattacks posed significant challenges for the fledgling Texian forces attempting to maintain control over Goliad. These events set the stage for a battle that would have lasting significance in shaping Texas history. Significance of the Battle of Goliad The Battle of Goliad holds significant historical importance due to its impact on the struggle for control over the region and the subsequent events that shaped the history of Texas. This battle had long-term effects that reverberated throughout the Texas Revolution and beyond, making it a pivotal moment in the fight for freedom. - The strategic implications of this battle cannot be overstated. By seizing Goliad’s supplies, the Texian forces dealt a major blow to their Mexican counterparts. This victory allowed them to gain access to crucial resources such as weapons and ammunition, enabling them to continue their fight against Mexican forces. In addition to these emotional impacts, there were also practical consequences resulting from this battle. The capture of Goliad provided a strategic stronghold for Texian forces in their efforts to secure control over Texas. It established a base from which they could launch further attacks and consolidate their power in the region. The significance of the Battle of Goliad extends far beyond its immediate outcome. Its long-term effects would shape not only the course of the Texas Revolution but also influence subsequent events that would culminate in Texas gaining its independence from Mexico. Transitioning into the next section about ‘legacy and impact on the Texas Revolution,’ this pivotal battle set into motion a series of events that would ultimately determine Texas’ fate in its struggle for freedom. Legacy and Impact on the Texas Revolution One of the lasting legacies and impacts of the Battle of Goliad on the Texas Revolution is its role in rallying support for the Texan cause and galvanizing individuals to join the fight for independence. This crucial engagement served as a catalyst, igniting a sense of patriotism and determination among Texans. The battle demonstrated the resilience and determination of the Texan forces against Mexican authority, inspiring others to take up arms. The legacy of this battle lies in its significance as a turning point in the Texas Revolution. The Texan victory at Goliad boosted morale and provided a much-needed boost to their confidence. It showcased their ability to take on and defeat Mexican forces, which further encouraged other Texans to join their cause. Additionally, the impact of this battle can be seen in its contribution towards securing vital supplies for the Texan army. By seizing control of Goliad’s supplies, including weapons and ammunition, the Texans gained a significant advantage over their Mexican counterparts. This bolstered their military capabilities, enabling them to continue fighting for their freedom. One cannot overlook the legacy and impact that the Battle of Goliad had on both rallying support for Texan independence and providing essential resources for their cause. Its role as a pivotal moment in history continues to inspire those who desire freedom and serves as a reminder of what can be achieved through unity and determination. Frequently Asked Questions What was the outcome of the Battle of Goliad? The outcome of the Battle of Goliad resulted in repercussions and consequences for both sides. It had a significant impact on Texas history, shaping the course of events in the fight for freedom. How many casualties were there during the Battle of Goliad? The casualties in the Battle of Goliad resulted in a significant impact on the local population. The exact number of casualties is not mentioned, but it is clear that the battle had profound consequences for those involved. Were there any notable leaders or commanders in the Battle of Goliad? Notable leaders in the Battle of Goliad were James W. Fannin, commander of the Texian forces, and Juan Nepomuceno Seguín, a Texian scout and courier who played a key role. Did the Battle of Goliad have any impact on the overall outcome of the Texas Revolution? The Battle of Goliad significantly affected the outcome of the Texas Revolution by securing crucial supplies for the Texian forces. This victory boosted morale and provided resources essential for their ultimate success in gaining independence from Mexico. How did the Battle of Goliad affect the local civilian population? The Battle of Goliad resulted in significant hardships for the local civilian population, with many facing displacement, loss of property, and food shortages. The impact on Goliad civilians was profound and enduring.
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Please join the PublicsLab for a workshop on transforming doctoral curriculum in the humanities and humanistic social sciences at The Graduate Center for the good of the public. Together, we will consider the promise and potential of doctoral education in the humanities to be both more student-centered and more public facing. We will address the following central question: How can we support graduate students in doing public scholarship and preparing for careers both inside and outside the academy? This two-hour workshop is required for anyone who intends to apply for one of our four $8,000 Doctoral Curriculum Enhancement Grants from the PublicsLab, but all Graduate Center faculty in the humanities and humanistic social sciences are invited to register. We will hear from the 2019 DCEG recipients about the progress of their projects and consider in detail what changes might be made specifically to the curriculum of a department. Attendance is free but early registration is recommended. Please reserve your spot by booking in the RSVP section below. Zoom details will be sent closer to the event. Date & Time: September 25, 11:00 am – 1:00 pm
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During the winter, he sells wholesale đồ sộ guides and stores. Bạn đang xem: ban buon tieng anh la gi At one time the store sold wholesale candy in one section, with another section mix aside for yarn goods. Miller's record album's were sold wholesale for 93 cents đồ sộ salesmen who sold them đồ sộ merchants who sold them đồ sộ the publilc for $1.98. More phàn nàn 2,000 of these slave-artists performed in more phàn nàn 170 noble theatres and were bought and sold wholesale while at the same time becoming stars. Now he is involved in a number of strands of the business, selling wholesale đồ sộ restaurants, hotels and bars and directly đồ sộ the consumer at markets. They can also be ordered direct from publishers and wholesalers. Xem thêm: me me linh ngoc dam They provide 29 liquor licenses đồ sộ wholesalers, manufacturers, retailers and the general public. It was constructed đồ sộ be the meeting point for producers, wholesalers, retailers and consumers for the entire country. He was a wholesaler and retailer of goods lượt thích salt, sugar, coffee and liquor. For example a wholesale list may contain details of companies which sell computers at wholesaler prices đồ sộ customers.
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Stomach or peptic ulcers are sores that develop in the stomach and the intestinal lining. They are generally caused by bacterial infections, prolonged use of non-steroidal anti-inflammatory drugs, and excessive consumption of alcohol. Find out some simple home remedies that can accelerate the healing of these ulcers, through this HolisticZine article. Stomach ulcers, also known as gastric ulcers, are open sores that develop in the mucosal lining of the stomach. They are also referred to as peptic ulcers, though most of the peptic ulcers generally develop in the duodenum, which is the first part of the small intestine. Generally, stomach and duodenum ulcers are benign, though rarely a few of them can become malignant or cancerous. Causes and Symptoms of Stomach Ulcers Sores or ulcers can develop in the lining of the stomach due to the damage caused by the hydrochloric acid (a component of the digestive juice). Earlier, the consumption of spicy foods and stress were thought to be responsible for causing gastric ulcers. But later, it was discovered that most of the ulcers are actually caused by a bacterial infection. The bacterium responsible for causing gastric ulcers is known as Helicobacter pylori. Apart from bacterial infections, some other important causes of gastric ulcers are, long-term use of non-steroidal anti-inflammatory drugs, cigarette smoking, and excessive consumption of alcohol. Even stress is believed to play an important role in their development. A burning sensation or pain in the upper abdomen, or below the breastbone, is the most common symptom that can be produced by this condition. The pain can be felt immediately after eating, though some individuals can experience the pain a few hours after having a meal. Other symptoms of this condition are, loss of appetite, vomiting, black stool, weight loss, blood in stool, and anemia. Stomach Ulcer Cure The conventional treatment options for gastric ulcers are medications, like antacids, acid blockers or H2 antagonists, proton pump inhibitors, and cytoprotective agents. If ulcers are caused by the H. pylori bacteria, then antibiotics are prescribed. However, in addition to these conventional medications, several natural remedies have shown their efficacy in treating this condition. Some such natural remedies for gastric ulcers are enlisted below: - Bananas can neutralize the stomach acid or the gastric juice. This fruit can also protect the stomach lining, and reduce inflammation and irritation. - Fresh vegetable juice, like carrot and cabbage juice can also provide significant relief. You can take cabbage juice either alone or mix it with carrot juice. Similarly, carrot juice can also be mixed with spinach or beet juice. Vegetable juices can help strengthen the stomach lining and heal the sores. - Fenugreek, if moistened with water, becomes mucilaginous. It can form a protective coating on the stomach lining, and accelerate the healing of the ulcers. - Lime contains citric acid and mineral salts, which can not only help promote digestion, but can heal the ulcers as well. Lime can be used in salads or taken as lime juice. - The leaves of wood apple are another effective natural remedy that can relieve the pain and discomfort associated with gastric ulcers. The leaves should be soaked overnight. The next morning, you can strain the water and then drink it. - Raw honey, especially the manuka honey can help heal the ulcers, strengthen the stomach lining, and destroy the bacteria that cause the infection. - Milk, especially cold milk is known to neutralize the stomach acid. So, it can be taken to alleviate the symptoms of gastric ulcers. Raw milk, especially raw goat milk can be more beneficial for this condition. Stomach or gastric ulcers, if left untreated, can give rise to some major complications, like gastrointestinal bleeding, perforation of the gastrointestinal wall, scarring of the tissues, and pyloric stenosis. Therefore, along with taking these remedies, it is essential to seek medical help. Equally important is to quit smoking, and limit the intake of caffeine, alcohol, and spicy and salty food. In addition to these, people having stomach or peptic ulcers should drink plenty of water, and eat several small meals in a day. Disclaimer: This article is for informative purposes only, and should not be treated as a substitute for professional medical advice.
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Many of you know this already, but my Grandpa passed away at the end of January. We expected him to go, and were glad that he no longer suffered the effects of age and illness. However, it was still hard. We only live a few miles away, so we saw him on a regular basis. This was my kids first close experience with human loss- we’ve had pets pass before, and they lost some other great grandparents when they were too young to understand much. So of course, I wanted to find books to help my kids through the grieving process. I haven’t found the perfect book- probably because every circumstance is different. But, here are a few books we have read that have helped us share and deal with our grief. I hope they might help you too. The Dragonfly Door by John Adams, illustrated by Barbara L. Gibson is a book that follows the lifecycle of a Dragonfly through a pair of nymph friends, Lea & Nym. Lea is older than Nym, so she changes from nymph to dragonfly ahead of Nym and Nym is left behind wondering what she did wrong for her friend to leave her. It’s a non-denominational way to express a belief in an after-life in a way kids might relate to. It has won many awards (Mom’s Choice, Benjamin Franklin, & Evelyn Turman Young Readers Book Award), and has beautiful illustrations. I personally found the text longer and more cumbersome than necessary, but my kids liked it and we had a great conversation. What’s Heaven by Maria Shriver, illustrated by Sandra Speidel Again, very heavy on the text, but sweet pastel illustrations lend to an angelic feeling in this book. I read it to my kids while they were eating dessert so that their attention span was longer than normal. Despite the long text, there were great discussion points and lots of questions and answers that children deal with whenever someone dies. It follows the journey of Kate, who has just lost her Great Grandmother as she comes to understand that when we lose someone to death, they are still a part of us because they have loved us and taught us things. Grandpa and Me and the Wishing Star by Barbara J. Porter, illustrated by Dilleen Marsh This one is also an award winner. Yet again, lots of text (it seems to go hand-in-hand with the subject). This book reinforces my personal LDS beliefs about death and was a great fit for my kids when their Great-Grandpa passed away. The book starts with a little boy named Jamie and his Grandpa who are best friends. But one day Jamie comes home from school and sees Grandpa being taken away on a stretcher. Later he finds out that Grandpa passed away and he is angry at God for taking him. Jamie goes through some of the stages of grief in a realistic way that I feel is useful for kids to read about so that they know that those feelings are a normal part of grief. My kids had some special experiences with my Grandpa and were able to be with him right up to the end, so they had a lot of feelings to work through. Always my Brother by Jean Reagan, illustrated by Phyllis Pollema-Cahill Grief is a part of life here on earth- we love people and we miss them when they are no longer with us. What are some of your recommendations of books that help children of all ages through this natural, but often painful process of grieving for a loved one?
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No Bake Almond Butter Balls No bake almond butter balls are the perfect healthy snack! Each bite has just the right amount of sweetness, a bit of fiber, and some protein to keep you full Here's what you'll need... – 1 cup medjool dates pitted – 1 cup old fashioned oats – 1 cup unsweetened shredded coconut divided – ¼ cup almond butter – 3 tablespoons ground flaxseed – 2 tablespoons almond milk – ½ teaspoon ground cinnamon – ½ teaspoon vanilla extract – pinch fine sea salt - Food Processor - Silicone Spatula - 2 tablespoon Cookie Scoop Add dates, oats, ½ cup shredded coconut, almond butter, flaxseed, almond milk, ground cinnamon, vanilla extract, and a pinch of salt into a high-powered food processor. Pulse until ingredients are finely ground and fully combined. Roll 2 tablespoons of the mixture into a bite-sized ball. Place the remaining ½ cup of shredded coconut on a plate. Roll the outside of the almond butter balls in the coconut. Eat immediately, or store in an airtight container in the refrigerator for up to one week. Swipe up for full recipe.
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Learning to cut concrete can seem like an intimidating process if you’re a DIYer, but don’t fret, cuts less than 6” deep are more than doable with a little knowledge and some basic tools. There are numerous reasons you might need to cut into concrete, including to repair cracks in concrete, creating control joints in a freshly cured slab, or if you’re building a custom concrete project like a planter or table. If you’re cut is less than 2 1/4” deep, then you likely already have most of the required tools lying around the garage or toolshed. Let’s take a look at the best methods to cut into concrete, including how to get the job done safely and with minimal risk. Tools & Materials The exact tools needed will vary somewhat from one job to another, but the main thing to remember is that if your cut is less than 2 ¼” deep you’ll be able to use a standard circular saw. Deeper cuts will require a special walk behind concrete cutting saw, which can cut 17”+ in the case of larger models - Circular saw - Walk behind concrete saw (for deeper and larger cuts) - Dry or wet-cutting diamond blade - Shop vacuum - N95 breathing mask with face shield - Chalk line or spray paint - Cold chisel and sledgehammer - Drop cloths Cutting Concrete – Step-by-step Guide Step 1: Choose Your Cutting Tool If you only need to make a small cut in concrete you can do a decent job with just a small sledgehammer and cold chisel. This is not the most accurate or efficient method though, and only really works well for smaller jobs. If you’re cutting task is a little more complex, then you’ll likely want to step up to using a circular saw. A circular saw combined with a decent diamond cutting blade will do a surprisingly good job of making cuts in concrete. The only real issue with using a circular saw – besides your depth being limited to 2 ¼” for a standard 7 ¼” saw – is that you’ll need to come up with your own dust collection system. Concrete dust is a serious health hazard, and too much exposure can cause silicosis, an incurable respiratory condition. Some circular saws come with a port for attaching a shop vac too, which will be helpful in keeping the level of dust down. Other things you can do are use a hose to create a small stream of water in front of the saw or have someone hold the shop vac next to the saw to collect dust as it comes out. If you’re going to go with the hose method, you’ll want to go with a wet-cutting diamond blade – as these are built for cutting in wet conditions. If you’re going with a wet-cutting saw, then keep in mind the water will also work to lubricate the blade as well as keep the dust down. You can also use water when cutting with a dry-cutting blade, but it isn’t necessary. And if your cutting job is going to require particularly deep cuts, then renting a walk-behind concrete saw makes sense. These saws are purpose-built for making cuts in concrete, feature deeper cutting depths, and integrated water systems, and are self-propelled so their easy to use. Renting a gas-powered saw is another good option if you need to make a large volume of deep cuts. Step 2: Safety Prep As mentioned previously, cutting into concrete creates a lot of harmful concrete dust. Before you start cutting anything, make sure to properly prepare the area as well as have the necessary safety gear on hand. As far as preparing the surrounding area, make sure to block off the work area from the rest of the building. Use drop cloths or plastic sheeting to seal off any windows or doorways, as well as cover any ventilation nearby. You’ll also want to make sure you use a GFCI (Ground Fault Circuit Interrupter) extension cord for your electric saw. These cords are designed to prevent electric current leaking, as well as prevent electrocution, burns, and shocks. For your own personal safety, the most important thing to do is to make sure you have proper breathing protection. Ideally a full-face shield with an integrated N95 respirator. A half-mask respirator and a good pair of safety goggles will also work. In addition, you’ll want to wear steel-toe boots, ear protection, and knee pads, but the most important thing is the respirator and eye protection. Also, make sure anyone assisting you has the same level of safety gear. Step 3: Mark the Cut Cutting into concrete is a little trickier than cutting into wood and other softer materials. It’s more difficult to correct a cut once you start to veer off, so you’ll want to do a good job measuring and marking out the cut before you get started.A chalk line is a useful way to mark out the cut, but you can also use marking spray paint or even score a line in the concrete using a sharp chisel. Step 4: Start the Cut If you’re cutting on the floor, then the dust collection will be easier than if you’re cutting into a vertical surface like a wall. Start the cut by making a slow plunge cut into the concrete. Once your blade has reached its proper depth, slowly push the saw forward along the line you created in the previous step. If you don’t have an integrated dust collection system, then have your assistant hold the shop vac near your saw’s dust port or trickle water in front of the saw to keep the surface wet. Be very careful when guiding the saw not to veer off course. I’ve made this mistake before and it results in a poor-looking final result as you’ll need to reposition the saw and make another plunge cut. Step 5: Utilize a Guide Board to Complete the Cut A guide board can be helpful for making a straight cut. A guide board is simply a straight 1” deep piece of scrap wood as long as the cut line that you run your saw along. Depending on the depth of the cut that you need, you may need to remove the guide board after the first pass and continue with a second pass without the board to deepen the cut. After the first pass, the saw blade will be guided by the first channel, so you won’t need the guide board to keep your cut straight. Featured image source.
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The market for vintage furniture is blooming, and the value of these pieces has soared too. What was once considered a second-hand piece of furniture is now something you can buy in much better condition than many modern pieces. Art deco originated in Europe in the 1920s and often appeared futuristic. The pieces were made with a focus on comfort and practicality, and they borrowed elements from classical architecture or sometimes even cave paintings. This style includes artistic elements like gears, rays of light, electricity, water vapor waves, and symmetry to make each piece elegant yet visually stimulating. Vintage furnishings are like a time capsule to the era in which they were designed and built. It is the best way to bring past pieces of furniture into your home and make them more appealing, giving your home a vintage feel. The room’s look will likely improve when you use vintage furnishings, as they suit both modern and traditional décor. There is also a huge variety of options for modern furniture that will fit into any deco or home design, including unique tables and chairs with unusual shapes. These pieces can be used to create a more upscale look. In recent years, people have moved away from using traditional interior décor and instead focus on creating their own personal style. This means that the market for vintage furniture is booming in popularity, and it is one way of taking advantage of this style trend. You can use a lot of the pieces in your home to make the space look a little more like the 1940s or 1950s than it does today. This is especially true with furnishings built in this era, which is the golden age of art deco furniture. The styles and design of vintage furniture may not mesh perfectly with your home style, but the key is to make sure you buy comfortable items. Take your time and find pieces that will add a touch of elegance to your home décor. No matter what type of furniture you choose, it will be stylish if you look for pieces built in a recent past style. Why buy vintage art deco furniture: One of the biggest reasons these pieces are so great is they are something people will remember. The resale value of these pieces is high, and the designs are worth remembering because so many people enjoyed them when they were first invented in the early 20th century. Art deco furniture is an investment, and the price increase of these pieces is proof that you can make money. Also, many of these pieces were custom-made to fit the space they are meant to be in; they were designed to be beautiful, useful, and made for comfort. Therefore, it makes the piece a very one-of-a-kind buy. What Vintage trends are making a comeback? French mirrors were a mainstay in Art Deco homes and can be used to add texture and depth to any space. French mirrors add an element of style and interest to any room. They have an vintage look, but they can be used in various styles. They create a pattern on the wall and come in several shapes and sizes. Antique dressing table Dressing tables are often considered one of the most important pieces of furniture in a girl’s room. They are antique pieces with a timeless look, making them very valuable and hard to find. Antique dressing tables are often very ornate and decorative. They can be crafted in ornate detail or use simple designs, but they all have a bit of history and style that make them attractive. Curved “bamboo” style chairs Bamboo furniture from the 1940s is becoming more popular as people want to add an earthy look to their modern homes. It is made of these plants and is lightweight and sustainable. Sunken arm and “bent” leg tables These are inspired by period furniture but take a modern shape to fit in with today’s design trends. The chairs are comfortable, stylish, and perfect for dining tables. They blend in well with the décor of any modern home. The art deco movement popularized geometric patterns, making these home décor pieces a popular choice for accent lighting. These lights are often retro-inspired and fit well with the modern gothic design. These huge clocks were made from ivory or mahogany. They were made to be luxurious and have a big presence in the room. They were often built in the early 20th century and designed to be larger than life. They are a great choice for decorating any space but especially dining rooms, as they will feel like they are making the room more formal. These are just a few of the many vintage art deco furniture trends currently making a comeback for those who want to bring them into their homes. Combining classic design with style and modern features makes these pieces an attractive choice. They give a sense of nostalgia to the times when life was simpler, and there was no such thing as fast-paced technology and mass production.
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What You Need to Know: - XSEED Games officially announced earlier today that Sakuna: Of Rice and Ruin will be showcased at this years BitSummit 2018 Volume 6, which takes place on May 12-13 in Kyoto, Japan at Miyako Messe. Developed by Edelweiss, the talented indie creators of the highly rated sci-fi shoot-’em-up Astebreed, Sakuna offers a genre-defying mixture of side-scrolling action with the complexities of rice cultivation set against a mystical backdrop based on Japanese mythology. - To know more about the title, be sure to keep it locked here once more details emerge! Marvelous Inc. will be located at Miyako Messe in the 2nd Exhibition Hall, Floor 1. In addition to Sakuna: Of Rice and Ruin, the company will have a playable demo on PlayStation 4 for X-Morph: Defense, and giveaways for participating attendees. - Sakuna: Of Rice and Ruin is in development for the PS4™ system and Windows PC in North America. Source: Official Press Release About Sakuna: of Rice and Ruin In Sakuna: Of Rice and Ruin, players take on the role of Sakuna, a proud yet lonely harvest goddess who is banished to a dangerous island with a group of outcast humans. Sakuna tames the island by defeating demons using farm tools as weapons while also making ample use of her “celestial scarf,” a magical item that allows her to grapple distant enemies and platforms. Along the way, she establishes a home in a mountain village, which serves as a base of operations for crafting weapons and cooking food. Additionally, as a harvest goddess, she grows rice by following a detailed process that encompasses everything from planting to harvesting. Through this process, across each of the four seasons, she’s able to improve the harvest and hone her battle skills alike. The painstakingly researched storyline incorporates Japanese history and legend, with its heroine facing off against numerous types of demons, great and small, as she traverses detailed landscapes rich with the iconography of classic Japanese mythology. A love letter to Japanese culture, Sakuna: Of Rice and Ruin is also an ode to the artistry of cultivating rice and features an engrossing simulation of the craft behind the agriculture.
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Hamlin ready for return to real racing ‘under a microscope’ All eyes will be on NASCAR’s return to real racing in one week and driver Denny Hamlin believes the sport and his fellow competitors are ready to do it “in the right way.” The NASCAR Cup Series will be the first major professional sport in the United States to return to live action next Sunday afternoon, with a 400-mile race at Darlington (S.C.) Raceway. The World of Outlaws sprint cars held a special race Friday night in Knoxville, Iowa, without fans, which appeared to go off without any serious issues. NASCAR has not held a live event since March 8 at Phoenix Raceway due to the COVID-19 pandemic and its races for the foreseeable future will be conducted without fans in attendance and under strict socially distancing guidelines. For the first two weeks, the races will all be one-day events with no practice or qualifying, except for the May 24 Coca-Cola 600 Cup race, which will have an afternoon qualifying session. Hamlin, who won Sunday’s eNASCAR Pro Invitational Series race at the virtual North Wilkesboro Speedway, knows the return to racing will be different but believes drivers and teams are ready to meet the challenge. “To me, when we go to California, Atlanta, whatever the second race of the season is, that is always the nervous moment I have. I usually don’t race anything in the off-season, don’t do any testing,” Hamlin said comparing the restart of this season to the start of a new one. “It’s difficult to be able to trust yourself and your instincts you know what you’re doing barreling off into Turn 1 at the proper speed. The good news is now that we know all these guys have got (sim) rigs. I guarantee all of them will be on iRacing at some point out there making laps at Darlington just to get re-acclimated.” Hamlin said the biggest question mark in his mind is the “unknowns” associated with the medical protocols that will be put in place. “You can read about them all you want. We also heard through the teleconference we had with NASCAR about the protocols,” he said. “But making sure you’re doing everything exactly the way that they want it. “Obviously, there will be a huge microscope on how we’re doing things, making sure it’s done in a safe manner. For all of us, it’s just the unknown of making sure we’re doing it the right way. “After the first week I think it will be easier and people will have a better understanding. Certainly the first week there will be some questions that I’m sure drivers will have.” When it comes to the actual competition getting underway, Hamlin believes there will be a “slow-go” approach even though with no one having been in a race car in over two months, one might think drivers could tempted to quickly release their pent up frustrations. A timid return “I envision people are going to be pretty timid, at least for the first few laps, just trying to understand, checking your travels. There’s plenty of times where these things unload, the cars are hitting the race track (and) you’re not ready to be in a pack quite yet. That will certainly be different,” Hamlin said. “But we do have the data from last year. I think everyone is going to be pretty confident going into Turn 1 that the travels are right. I’m sure the crew chiefs are going to be very conservative with their travels to make sure the car doesn’t hit the race track on the first run. “I think all in all it’s going to be like an old shoe. I don’t think from the TV’s perspective fans will see anything different than just a normal race that they would normally see at Darlington. Source: Read Full Article
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At least six people were killed and 13 others injured when a suicide bomber targeted a minibus full of delegates involved in Somalia’s parliamentary elections Thursday. The bomber detonated an explosive vest near a checkpoint leading to the presidential palace in Mogadishu, according to security officials and city’s ambulance service. Witnesses said the bomber ran after the bus, trying to grab its back door, but blew himself up as police drew their guns and shouted at him to stop. “My team carried six dead bodies and transported 13 injured people to the hospitals,” said Abdikadir Abdirahman Adem, director of Mogadishu’s Aamin Ambulance Services, told VOA Somali. “We can confirm that a terrorist suicide bomber carried out the attack and that those killed and injured are all civilians,” Aden said. The al-Shabab militant group quickly claimed responsibility for the attack. It was not immediately clear if members of the delegates were among the casualties. Somali Police Spokesman Col. Abdifatah Aden Hassan said police would release a full report with details on those killed and injured. The attack comes as Somalia’s parliamentary elections continue in different parts of the country. Political leaders are trying to meet a self-imposed deadline of February 25 to finish the delayed polls. Electoral delegates on Thursday chose six additional lawmakers from the southwestern town of Barare and five more to represent northern regions of Somalia, bringing the total of elected members of parliament to 124 — slightly less than half of the 275 seats to be filled. The elections began on November 1 and were originally scheduled to end by December 24 but were held up due to political disputes and logistical challenges. Once the lawmakers are selected, parliament will elect a new president. The United States and other international Somali partners are pushing for quick and credible elections. On Monday, the U.S. barred current or former Somali officials and others accused of undermining the democratic process in Somalia from traveling to the United States. U.S. Secretary of State Antony Blinken said in a statement that the visa restrictions will apply to those who have encouraged and engaged in violence against protesters, intimidation of journalists and opposition members, and manipulation of the electoral process. “The best path toward sustainable peace in Somalia is through the rapid conclusion of credible elections,” Blinken said. “Somalia’s national and federal member state leaders must follow through on their commitments to complete the parliamentary process in a credible and transparent manner by February 25.”
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Leon, an 8-year-old black lab is retiring after 7 years of hospice service. He is retiring at the recommended age for his breed, says Alison Wagner, director of volunteer services for Hospice of Michigan and Arbor Hospice. Arbor Hospice of Ann Arbor, Michigan, adopted Leon in 2013 for patient visitations at retirement communities, assisted living facilities, end-of-life care centers, and homes throughout Washtenaw County and lived with a staff member. Wagner said therapeutic time with an animal can help fill a void for patients missing a companion. “One of the reasons why we think this is so important is because we see that some people as they’re coming into hospice, or just as their life is changing, as their disease progresses, they’re having to give up their pets,” Wagner said. Simply cuddling or petting an animal can reduce anxiety, lower blood pressure and heart rate, and ease depression. Because a primary goal of hospice services is comfort care, Pet Therapy, also referred to as animal-assisted therapy (AAT), is an ideal option for providing comfort to patients who often feel isolated. During visits to the hospice patients, pet therapy is a guided interaction between the patient and a trained animal. It also involves the animal’s handler. Animals interact with hospice patients during individualized visits per the patient’s comfort level. The physical benefits of hospice pet therapy are worthy of attention. It’s well-known and scientifically proven that interaction with a gentle, friendly pet can: - lower blood pressure, - improve cardiovascular health, - release endorphins (oxytocin) that have a calming effect, - diminish overall physical pain, and - produce an automatic relaxation response during the act of petting, reducing the amount of medication some patients need. The social and emotional benefits of hospice pet therapy can: - lift spirits and reduce depression, - decrease feelings of isolation and alienation, - encourage communication, - provide comfort, - increase socialization, - reduce boredom, - lower anxiety, and - reduce loneliness. Alana Knoppow, volunteer program manager at Arbor Hospice, said Leon’s support was significant for many patients, especially those who had trouble expressing their feelings to others. “He would just sort of cuddle up to them, give them a chance to pet him,” Knoppow said. “Some patients might even talk to him. Sometimes we’ve had patients who really don’t speak to any other people, but will open up and speak to a pet.” According to the Mayo Clinic, pet therapy can help people reach specific goals in their treatment. For example, patients with dementia and Alzheimer’s Disease can benefit from the socialization and activity associated with animal visits. Visitation between patients and animals promotes activity, conversation, and emotional connection. Often, simply the presence of the animal is all that is required to promote the positive effects. Some patients may have allergic reactions to certain animal species, however, pet therapy allows for all patients, regardless of allergies or other restrictions, to enjoy the company and affection of compassionate animals. While dogs comprise the majority of the animals in pet therapy programs, there is a wide array of species employed in providing comfort and companionship to hospice patients. - Dogs—By far the most popular choice for pet therapy, dogs are universally enjoyed by hospice patients for their loving, compassionate presence and ability to read subtle emotional and physical cues from humans. - Pigs—An alternative to those allergic to dogs or cats, pigs are a calm, affectionate, and intelligent animal companion. Pigs also are a viable alternative for patients who have had frightening past experiences with cats or dogs. - Rabbits—For patients who may be allergic to cats or dogs and desire a small, fluffy animal in their lap, rabbits are a perfect choice. Pet therapy rabbits provide patients with a calm, silent, and adorable companion. - Cats—Cats can provide a quiet, loving presence and promote a profound emotional connection with patients. Cats are among the most requested pet therapy species, ranking second only to dogs. - Horses—A very popular option for hospice organizations involved with pet therapy, horses, particularly miniature horses, are ideal for providing patients with a kind, calm, and quiet companion that facilitates communication and bonding. - Birds—Birds can be a fun and uniquely entertaining animal companion. While often requiring a great deal of training before being ready to serve, the cheerful and bright disposition of birds can bring laughter and enjoyment to patients, caregivers, and families. Hospice pet therapy programs also have a significant impact on the overall range of motion and bodily strength of patients. Active movement can often be neglected, especially in older patients, and so pet therapy visits promote motion and activity as hospice patients play, cuddle, pet, and interact with their animal companion. “They seem to have the sixth sense about knowing what a person needs,” Knoppow said. “It really does reach a place in a patient’s heart that I think people can’t reach in the same way.”
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Entrepreneurship is en vogue! Not a day passes by without reading or hearing about how entrepreneurship supports most European countries’ GDP growth, the groundbreaking innovations that entrepreneurial ventures bring about, or the importance of getting more young people excited about launching their own startup. Here at the Ecole hôtelière de Lausanne (EHL), our elective on developing entrepreneurial projects accounts for the most popular course in the final year of study. By the time students finish the course, the comment most often made is: “Why did we not have this course much earlier? There were so many ideas I already had in my first year of study!” Fact is, although these statements echo the entrepreneurial drive that resides within many young students, it also clearly pinpoints the lack of existing infrastructure available to help them. Yet, this does not mean that students need to miss out. In fact, from where I stand as a faculty of Strategy and Entrepreneurship, students have it in their hands to generate an entrepreneurial environment in any institution. The best example is our own Club des Entrepreneurs (CDE), which is a self-organized student body that has made it their mission to not only garner their own entrepreneurial interests, but provide a point of contact for any student who may have a potential idea to develop. The CDE and comparable collective actions are generally referred to as grassroots initiatives. Grassroots initiatives are collectively self-organized actions through a bottom-up rather than top-down approach, with the aim of encouraging a community with similar interests to take responsibility and initiative to drive a goal. This kind of movement relies on individuals who are willing to drive the change that they are concerned about from the ground-up. Hence, the reason we also refer to these initiatives at grassroots is linked to the fact that it tackles the problem where it is felt – at the root. I had the opportunity to speak with Mark-Oliver Wiesner, the head of the Club des Entrepreneurs, to understand where he sees the club's place in the overall lifecycle of a student’s entrepreneurial development. He was kind enough to provide us with three important takeaways on why grassroots programs are needed and how the CDE helps students in developing their entrepreneurial ideas into potential startups. 1. Democratizing knowledge One of the biggest roadblocks entrepreneurs’ face in the early stages of launching their business – which is not only true for young entrepreneurs – is knowing where to find reliable information. Generally, here many student entrepreneurs face one of two options: either acknowledged institutions like incubators, which have highly competitive access requirements and are hence limited, or companies that make a business of supporting entrepreneurs and often turn out to be expensive. Here is where grassroots programs like the CDE can be tapped into by leveraging the context they operate in. It is not about replacing courses in the curriculum of a school or competing with actors in the wider entrepreneurial ecosystem. It’s about giving students of the community a first point of contact to not lose the momentum in a chase for information that may either be expensive or unreliable. Concretely speaking, the CDE taps into the resources that the Ecole hôtelière de Lausanne has to provide, whether this is by encouraging faculty to offer free-of-charge sessions, access to the local innovation hub or granting financial support from the school to organize initiatives for the student body. As Mark-Oliver pointed out: You cannot teach someone to have creative ideas - that is born out of the moment or circumstances, but you can teach execution. Here the club makes the sometimes hard to reach insights accessible – free of charge and reliable! 2. Hands-on opportunities The second point Mark-Oliver pointed to was the importance of providing opportunities. Every venture must start with the first action one takes. Yet, often enough student entrepreneurs don’t even know what that first step needs to be. Here grassroots programs can provide a broad and wide ranging portfolio of activities that speak to the different needs of their community. On the formal side, a great opportunity are talks with entrepreneurs that explain how they tackled the initial steps in their entrepreneurial career. Not only do these encounters break some of the myths residing around entrepreneurship, but they showcase that it’s ok not to have all the answers. Entrepreneurship is about creativity and giving people the chance to create. While talks and exposure to entrepreneurs are an important tool to allow for vicarious learning from the mistakes that every entrepreneur ultimately makes, it is equally about taking concrete action for the CDE. After all there is a famous saying about learning: “Make me hear and I will forget. Make me see and I will remember. Make me do and I will understand!” To that point the CDE provides more informal initiatives that range from competitions on food waste reduction to blockchain seminars. Regardless of the focus an initiative takes, the mission is direct engagement with the matter. For instance, in line with the Sustainability Week held at the Ecole hôtelière de Lausanne in early May, the CDE set out a competition on how to reduce waste in the area of finger food, allowing the winning initiative the opportunity to be implemented on campus. In sum, the CDE sees itself as planting seeds that will then be grown by the community. After all, as Mark-Oliver points out: “Entrepreneurship is about creativity and giving people the chance to create”! 3. Connecting the dots It may sound like a cliché, but one cannot go about it alone. Grassroots initiatives are centrally there to build a community and network that collectively work with each other. Particularly while still in university environments, student entrepreneurs feel a vacuum between their university life and their ability to transfer over to the entrepreneurial scene. Here early connections are forged while still in their studies, student entrepreneurs can access the wider ecosystem, allowing for a smooth transition rather than a cold start after graduating. For instance, the CDE forges connections with EHL alumni as well as the wider entrepreneurial ecosystem of the canton Vaud and beyond. Once a year they also organize the business angel’s dinner that grants up to three projects the opportunity to pitch for financial support. This access is not only crucial for the resource access, but the community building that naturally occurs. After all, the CDE is formed of students, who themselves cannot be a center of competence on all accounts – but if they are not – they are sure to find you the right contact. What can we take away from this interview? Grassroots programs are central to fill a void in the lifecycle of a student entrepreneur. For those organizing entrepreneurial grassroots initiatives it also grants the first opportunity to follow through on their entrepreneurial ambition, while generating positive externalities. This further allows for the support of those that may otherwise see their ideas die without access to crucial resources and the right network when they need it the most. After all, entrepreneurship is only 1% about the idea, 99% is execution!
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In Houston, there are a lot of dumpster rental companies to choose from and the internet is a great place to start. Houston is the fourth largest city in the United States and it has been consistently voted as the best place to live in America. That is a great honor and dumpster rental companies in Houston should be proud to be serving their community. When you are looking for a dumpster rental in Houston, TX and in Texas, we are the go-to company for you. Our dumpster rental service can certainly make your life much easier in a number of ways. First of all, you do not have to worry about any kind of construction work or home renovation work. This is because you are going to have a team of professionals do it for you. Furthermore, you are going to have a wide range of dumpsters to choose from. Whether you want a small dumpster to throw out your trash or a large dumpster for a demolition project, we are more than happy to provide you with a rental to match your needs. Roll Off Dumpsters Roll off dumpsters are becoming more and more popular for contractors and business owners who want to dispose of large amounts of garbage or debris. Sometimes referred to as RUBs or containers, roll off dumpsters are rented on a per-dump basis. They are great because they are simple to use and easy to transport. You’ll need a truck to transport the dumpster from the rental site to the job site, but once it’s there, the rest is easy. Just use the winch to lower the bin onto the ground and fill it! Once you’re done, the winch will haul it away for you. What Is The Dumpster Rental Process Handled By The Professional Houston’s And Texas Dumpster Rental Service? The dumpster rental process is handled by professional Houston’s and Texas dumpster service providers by following these steps. The customer should call up the company and make a booking. The company will assess the time period required to complete the job. After which they will deliver the dumpster to the customer within the specified time period. The customer should check with the company whether they will have to pay for the dumpster. Once the dumpster is delivered the customer can start disposing off the waste materials. While the disposal is in process the customer should check if the hauler’s equipment does not damage the driveway or the lawn. The customer must also follow all the safety measures as instructed by the hauler. There are a number of advantages of hiring a dumpster rental company in Texas and Houston, rather than doing all the work and research on your own. One of the main advantages is that they are experts in the field and they know where to find the right sized dumpster. They can help you find the right sized dumpster for your situation, which you might not have time to find on your own. They can also advise you on what you can and cannot dump in them, which is also important if you are looking to rent out a dumpster to an apartment complex, as they have to abide by certain rules and regulations. Another major advantage is that they can help you load and unload the dumpster, which may be a challenge if you are doing a large demolition project.
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Prof. Michael Wendt Purdue University, USA1 Talk Michael K. Wendt is an Associate Professor of Medicinal Chemistry and Molecular Pharmacology in the college Pharmacy at Purdue University. After completing his graduate studies at the Medical College of Wisconsin, Dr. Wendt became an American Cancer Society fellow at the University of Colorado Cancer Center. Dr. Wendt moved to... read moreCase Western Reserve University where he received a K99/R00 transition award from the NCI. Dr. Wendt joined the faculty of Purdue University as an Assistant Professor in 2014. In 2016 Dr. Wendt became an American Cancer Society Research Scholar, and in 2022 was appointed as a Showalter Faculty Scholar in life sciences at Purdue. Research in the Wendt lab focuses on the molecular mechanisms of breast cancer dormancy and metastasis. In particular the Wendt lab studies growth factor signaling processes emanating from receptor tyrosine kinases, and how signaling and therapeutic response is affected by various aspects of the tumor microenvironment such as the extra cellular matrix and hypoxia.
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2023-09-27T11:18:14Z
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Now is the perfect time to start your landscape design and installation process. Many people are unsure if they need a professional landscaper for their property. Most times, the answer is YES! Landscapers have the knowledge to create beautiful landscapes to fit your property, your budgets, and your wants. They know what grows best in what regions and types of soil. This is crucial when trying to create a landscaped property that will thrive. Landscape companies will take the care to find what fits your property and work to achieve any dreams you may have! Landscapes can range from xeriscapes to extravagant landscaped areas with water features and hardscapes. The design options are endless when hiring a professional landscape company. Your landscapes will depend on what you wish and the type of property you have. We can create landscapes using beautiful flowers, shrubs, plants, and even rocks. It is all dependent on what our client desires. If you are looking for a unique landscape, hiring a professional is the best choice. Whether you have an idea of what you want or want them to design the landscapes for you, you will be pleased. Once the design portion is finished, your landscapes will need to be installed on your property. This is not only exciting for you but also exciting for the landscaping company. Landscapers love seeing their designs come to life! Huskie’z Landscaping provides beautiful landscape installation for businesses and residential properties. We also offer hardscapes, sprinklers, and drainage systems to make your life easier! Before you start your own landscaping journey, contact a landscaping company. We guarantee you will love their attention to detail and the care they take in their landscape design and installation. Landscape companies will even provide maintenance for your landscaped property, including sprinkler adjustments and repairs.
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Hydria Water presents a new naming convention for products, Alpha to Omega. The new concept is part of the ongoing process of solidifying the brand’s identity, following the merging of Mellegård & Naij and VA Teknik Sweden into Hydria Water in January this year. – Since three companies have now become one and we have come together under a strong common brand, we also want the products to follow a consistent and uniform path, which reflects what Hydria Water stands for. By choosing the concept Alpha to Omega, we show that we are constantly looking ahead and are focused on constant development and innovation, says Ellen Gremo, Marketing Manager, Hydria Water. The naming convention being on the Greek alphabet comes from the fact that “Hydria” itself is a Greek word. – Hydria is a special kind of ancient Greek water vessel with three handles, one on each side and one in the middle between them, for stability when pouring from the vessel. The symbolism of the three handles is especially clear now that three companies have become one, we have all gathered in the same Hydria, says Ellen Gremo. All new products developed and manufactured by Hydria Water will continue to be named using letters from the Greek alphabet. First up was the new Sand Washer Alpha SWA, which was launched just before the summer. It is a new, market-unique solution developed in collaboration with Alpha Solutions, a world-leading company in CFD simulations, to optimize the functionality of the sand washer. As a result, we have now been able to increase both efficiency and the degree of purity throughout the process. Over the course of the rest of the year, more products and solutions will be rolled out. Digital Beta, the second product under the new naming concept, is a digital solution that Hydria Water has developed to simplify the management and control of the processes that are currently being tested. Later this fall, the new Wash Press Gamma WPG will also be introduced. It will then become the third Hydria Water product to be named according to the new concept. – Wash Press Gamma, which we look forward to telling you more about soon, is a revolutionary solution where the utilization of power in existing facilities is optimized, which provides enormous customer benefits, says Andreas Riedel, CTO, Hydria Water. – With this launch, we have also brought in our newly developed machines under the Hydria Water brand. This is an important part of the effort to solidify Hydria Water’s new identity for the market and our customers and to also show that we are ready to offer solutions in water treatment with society’s future needs in focus, says Ellen Gremo, Marketing Manager, Hydria Water. Products that are part of the existing assortment from Mellegård & Naij and VA Teknik Sweden, respectively, will retain their current product designations.
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iFlicks on Twitter |Written by Ivan Radford| |Wednesday, 21 September 2011 07:59| Director: Nicolas Winding Refn "What do you do?" asks Carey Mulligan, sitting nervously in the kitchen. Ryan Gosling stands still. He says nothing. Then, after a few seconds, he smiles slowly. "I drive," he says. That's pretty much all there is to Drive: Nicolas Winding Refn's thriller is made up of 10% car chases, 20% Carey Mulligan, and 70% Ryan Gosling standing still, saying nothing, pausing for a few seconds, and then smiling slowly. Needless to say, it adds up to one big load of awesome. For a film with a verb as its title, Drive is surprisingly stationary. The story, which sees a Hollywood stunt driver get involved with his next door neighbour (Mulligan) and her husband's post-prison heist, has a definite lack of action, but that's no bad thing. Winding Refn is content to drift casually along with an 80s cassette tape playing, soaking up the retro atmosphere - it's a mature approach that accelerates away from the giant skid mark that was Valhalla Rising. The candy floss lettering of the opening credits and Gosling's shiny jacket scream period cheese, but beneath the bonnet, Drive has all the anti-social tics of Jean-Pierre Melville's loner Le Samourai - a man who, as he steps out from behind the wheel and moves towards another human being, ends up in a world of trouble. And so the sugary Michael Mann sunsets and gorgeous cinematography are loudly punctuated by bursts of graphic violence. That's where Ron Perlman comes in. Becoming mixed up with loan sharks and gangsters, Gosling's anonymous superhero finds himself faced with Perlman's typically butch villain, a woman who looks nothing like Christina Hendricks and a surprisingly intimidating Albert Brooks. Together these threatening characters keep the plot moving, mainly because they do all the talking; Gosling and Mulligan cruise through their romance barely saying a word, and it's testament to both that they still engage. Gosling, in particular, cements his leading man skills with all the quiet laid-back charm of Steve McQueen or Alain Delon - rarely has a violent sociopath been so likeable. "A real human being... and a real hero," sings the movie's unsubtle signature tune, emphasising Gosling's transformation from car mechanic into Man with No Name. Yes, it's a self-aware mix tape of Taxi Driver, a Western, and classic 60s European thrillers, but Drive has a pace all of its own. It may take time to settle into the loose seats, but once it's in gear, it's a seriously smooth ride. By the end, you'll be standing still and not saying much, but you'll be smiling all the way home. 10% cars, 20% Carey Mulligan and 70% Ryan Gosling smiling slowly, Drive is 100% awesome. What did you think?( 2 Votes )
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|Raindance Review: Montevideo - Taste of a Dream| |Written by Selina Pearson| |Friday, 30 September 2011 17:31| Montevideo is the romanticised whimsical tale of the first Yugoslav national football team and their journey from the streets of Belgrade to the first World Cup in Uraguay. The film has done incredibly well in its homeland of Serbia, and is their foreign language entry for the Academy Awards - it's also rather brilliant. The tale is told through the eyes of Stanoje, a kid who hero worships his older friend 'Tirke' Tirnanić - he has skills and fantastic hair. Enter 'Mosha' "He was great, even when football was small" Marjanović, the talented rich kid everyone fawns over. He comes with a cart load of trouble, living the footballer lifestyle long before Best or Ronaldo. The Croats are incensed when their football federation head office is relocated Serbia, and so boycott the national team, leaving the Yugoslav football federation a massive mountain to climb if they are to get to Montevideo; no team, no head coach and no money. The Serbian players must overcome local rivalries and personal differences through the medium of bar fights and football if they are to respond to Jules Rimet's invite to Uraguay. Director Dragan Bjelogrlic shoots everything with a nostalgic feel, mostly achieved by using lots of hats and filters, and though it has a whimsical - almost Amelie-esque feel - it doesn't downplay the political turmoil in the background. And as an underdog story, it has a kinship with Cool Runnings. Its only problem is that at 2 hours and 20 minutes, it's a little too long. Montivideo is a lovingly made nostalgia piece from a time when men were men, leather balls had laces and FIFA President wasn't an insult.
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Monday, December 18, 2006 Hold the Front Page: LibDems Reshuffle Team for 'Snap Election' The LibDems believe that Gordon Brown might call a snap election in October. Ming Campbell has therefore reshuffled his team. It's interesting that Steve Webb has been appointed to write the manifesto. Webb is one of the more left wing and cerebral LibDem MPs. Ed Davey swaps positions with Norman Lamb, who becomes Health Spokesman, while Davey becomes Ming's Chief of Staff. Susan Kramer moved to becomes DTI spokesman, while Lynne Featherstone joins the front bench top team at International Affairs.
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Optional Practical Training (OPT) Optional Practical Training (OPT) is work authorization available to international students who have been in valid F-1 status for at least three consecutive quarters and who plan to seek employment in the U.S. in their field of study. OPT allows F-1 student to work legally for a period of up to one year, full-time. OPT is recommended by an advisor at the International Center, but final approval is granted by the U.S. Citizenship and Immigration Service (USCIS). - Valid F-1 status - Enrollment in at least three consecutive quarters - NOTE: If summer is your last quarter you must be enrolled in at least six units, which is considered full-time or be approved to go part-time/filing fee in your last quarter. If you will take online classes during your last quarter, please read about Online Course requirements before applying for OPT. - Pursuing a Bachelors, Masters, or Ph.D. degree - Employment must be related directly to the major area of study OPT Information Workshop The International Center will offer OPT Information Workshops to assist you with questions you have about the OPT application process. You will receive an overview of a complete OPT application and will review the most frequently asked questions about OPT. You are encouraged to bring your OPT application materials to the workshop to review with International Center staff. Arrive on time at the beginning of the workshop you plan to attend. The workshop will begin as scheduled below and last for one hour. |OPT Information Workshop Schedule| Every Wednesday: 9:30am
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Inside a Skater’s Bag: Tools and Accessories Figure skating accessories might seem like a small part of the sport—but these items can play a major role in a skater’s everyday life. What they carry in their bag may seem trivial, but this gear can make or break how a practice might go or how stressful a competition may be. Planning ahead and figuring out what to keep in each of your figure skating bags is essential to the sport. Figure skating is already quite demanding, so you don’t want to add the stress of not being sure you packed an extra pair of tights when yours get a run in them on the day of an important competition. At Riedell, we’re passionate about providing all the advice skaters need to succeed. So today, we’ll be diving into the items every skater should bring in their practice and competition bags. What’s Inside a Skater’s Practice Bag? A skater’s bag will likely look a lot different when they are heading to practice versus a competition. Your practice bag may not require some of the items your competition bag will. So then, what are some of the things you might find inside a skater’s practice bag? Extra Gloves, Ear Warmers, and Layers Something that a figure skater should always keep in their practice bag is extra layers. The ice skating rink can be quite cold at times, and if you are not fully prepared then your muscles can get cold—making it hard to practice. Plus, having the option to take layers off if you get warm is better than not being able to put them on when you’re cold. Ice Skates and Skate Guards Of course, some of the most important items to keep in your skate bag are your skates. No skater wants to get to practice and realize they left their skates at home. Making sure they are properly cared for is also important, so keeping skate guards in your bag is also important. A skater should wear their skate guards when they are not on the ice in order to protect the blades and keep them sharp. A Drying Cloth & Soakers During practice, you’re likely to accumulate a lot of moisture and water on your skates and other accessories. You’ll want to have a dry cloth to wipe your skates off to keep them protected from the elements. After drying off your skates and blades, put terrycloth soakers on the blades to wick away any moisture and condensation that forms on the blades. A Spare Outfit Along with having extra layers, you’ll want to bring along a spare outfit. This can be something you change into after you practice—or even just another practice outfit in general in case the one you’re wearing gets wet or ruined in some way. Having a clean, dry outfit to change into after practice will make any skater much more comfortable. A Water Bottle and Healthy Snacks At practice, you’ll likely become sweaty from all the hard work you’re putting in. Having a water bottle is essential to stay hydrated and focused throughout the entire lesson. Having healthy snacks will also be beneficial after a long, strenuous practice. What’s Inside a Skater’s Competition Bag? While there are many items that you will also have in your practice bag, your competition bag may include some things you won’t necessarily need in practice. Competition Registration Information Making sure that you have all the correct registration information is crucial to a smooth competition day. You’ll want to have documents that include your event number, time of competition, rink, and more. You don’t want to be frantically trying to figure out when your warm-up time is and end up missing it altogether. Copies of Your Music It is critical to have multiple copies of your music when you’re heading to a competition. Make sure you give a copy to your coach to ensure that more than one person has it. You should have another copy for your warm-up or practice time, too. Extra Tights and Competition Outfit Having extra tights is crucial for a competition day. You don’t want to worry about getting a run in your tights and not being able to fix it with clear nail polish. Packing an extra pair will be a lifesaver in these situations. The same goes for extra competition outfits. Having just one extra can be beneficial in case yours gets damaged and can’t be used. Hair and Makeup Accessories While most skaters get ready before they get to the rink, having some makeup or hair accessories for touch-ups can be beneficial. Include items such as hairspray, hair ties, and blush. Be Prepared for Practice or Competitions with Riedell Skates Being properly prepared for practice or a competition by having all of the necessary equipment and accessories can help relieve a lot of stress for skaters. Making sure you have the proper skates is essential to help you feel prepared. With Riedell, you can get custom-fitted skates tailored to your unique feet. Contact us today about finding your perfect skates!
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Jan 22, 2020 Is clutter preventing you from having room to receive in your life. Choose what to release in this week's episode. If you enjoy Bible reading plans and mini devotionals, you can receive my 5-day Bearing Fruit devotional today for free! CLICK HERE Blog: I Choose My Best Life Connect with Saundra:
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March 29, 2023 (ICME Alum) Lek-Heng Lim uses tools from algebra, geometry and topology to answer questions in machine learning. March 01, 2023 A team of scientists from Stanford and Mexico developed advanced versions of the algorithms used to reveal people’s ancestries to show how Polynesian mariners crossed a vast ocean. October 12, 2021
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Your privacy is critically important to us. Idaho Mining Apparel and Supply is located at:Idaho Mining Apparel and Supply 804 E Mullan Ave PO Box 649 Osburn, ID 83849 USA (208) 556-5073 Updated January 1, 2021 Like most website operators, Idaho Mining Apparel and Supply collects non-personally-identifying information of the sort that web browsers and servers typically make available, such as the browser type, language preference, referring site, and the date and time of each visitor request. Idaho Mining Apparel and Supply’s purpose in collecting non-personally identifying information is to better understand how Idaho Mining Apparel and Supply’s visitors use its website. From time to time, Idaho Mining Apparel and Supply may release non-personally-identifying information in the aggregate, e.g., by publishing a report on trends in the usage of its website. Idaho Mining Apparel and Supply also collects potentially personally-identifying information like Internet Protocol (IP) addresses for logged in users and for users leaving comments on https://idahominingapparel.com blog posts. Idaho Mining Apparel and Supply only discloses logged in user and commenter IP addresses under the same circumstances that it uses and discloses personally-identifying information as described below. Gathering of Personally-Identifying Information Certain visitors to Idaho Mining Apparel and Supply’s websites choose to interact with Idaho Mining Apparel and Supply in ways that require Idaho Mining Apparel and Supply to gather personally-identifying information. The amount and type of information that Idaho Mining Apparel and Supply gathers depends on the nature of the interaction. For example, we ask visitors who sign up for a blog at https://idahominingapparel.com to provide a username and email address. The security of your Personal Information is important to us, but remember that no method of transmission over the Internet, or method of electronic storage is 100% secure. While we strive to use commercially acceptable means to protect your Personal Information, we cannot guarantee its absolute security. Links To External Sites We have no control over, and assume no responsibility for the content, privacy policies or practices of any third party sites, products or services. Https://idahominingapparel.com uses Google AdWords for remarketing You can set preferences for how Google advertises to you using the Google Ad Preferences page, and if you want to you can opt out of interest-based advertising entirely by cookie settings or permanently using a browser plugin. Idaho Mining Apparel and Supply may collect statistics about the behavior of visitors to its website. Idaho Mining Apparel and Supply may display this information publicly or provide it to others. However, Idaho Mining Apparel and Supply does not disclose your personally-identifying information. To enrich and perfect your online experience, Idaho Mining Apparel and Supply uses “Cookies”, similar technologies and services provided by others to display personalized content, appropriate advertising and store your preferences on your computer. Those who engage in transactions with Idaho Mining Apparel and Supply – by purchasing Idaho Mining Apparel and Supply’s services or products, are asked to provide additional information, including as necessary the personal and financial information required to process those transactions. In each case, Idaho Mining Apparel and Supply collects such information only insofar as is necessary or appropriate to fulfill the purpose of the visitor’s interaction with Idaho Mining Apparel and Supply. Idaho Mining Apparel and Supply does not disclose personally-identifying information other than as described below. And visitors can always refuse to supply personally-identifying information, with the caveat that it may prevent them from engaging in certain website-related activities.
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IEEE Joseph F. Keithley Award The IEEE Joseph F. Keithley Award in Instrumentation & Measurement* is presented for outstanding contributions in electrical measurements. It was established in 2001 and was presented for the first time in 2004. It is awarded by the IEEE. The award recipient is invited to receive the award and deliver a keynote address at the annual International Instrumentation and Measurement Technology Conference (I2MTC) or one of the I&M Society jointly co-sponsored conferences. Suggestions for strengthening nominations (not all-inclusive): When a candidate's accomplishments are within a team of people, the individual's unique accomplishment must be specifically and clearly delineated. The committee considers the individual candidate's accomplishments and not that of a group unless the entire group is nominated. Nominations must specifically and clearly show influence of one's innovation/accomplishment in a broad manner, not just in academia, or just in a narrow industrial application, etc. In addition, specific statements must be included indicating the impact of one's work in a broad way. The reference letters should also possess broadness by asking people who are keenly familiar with the candidate's work (from industry, academic, national/government labs, etc.). Also they must point to SPECIFIC impacts and not generality of the candidate's work. Global nature of one's impact of work is also very important. *The IEEE Joseph F. Keithley Award in Instrumentation & Measurement is Financially Co-Sponsored by the IEEE Instrumentation & Measurement Society and by Keithley Instruments, Incorporated. View Award Recipients Download Recipient List Nominate for Award More Information latest recipientS Eric W. Strid Retired, Board of Directors of Power Oregon United States K. Reed Gleason Form Factor, Inc. United States "For contributions to measurement fundamentals and signal processing techniques in instrumentation and measurement."
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When we are teaching, we obviously want our students to be learning. But teaching and learning are not the same things, and one thing (teaching) does not always result in the other (learning). We must transform our teaching so that students are actually learning. This is truly the intent of the NGSS — improve science instruction to improve science learning. And science learning is not just about content, but also about skills and a scientific way of thinking. When we are framing our instruction for the NGSS, we should consider the different instructional models available. While there are actually several models that would work well with the standards, I have found the 5E Model is the easiest and most effective way to transition your instruction to the NGSS. It allows you to work within the confines of the typical school, district, and state requirements without sacrificing the important opportunities for exploration and sense-making that support the NGSS Performance Expectations. While the 5E may be the easiest to utilize in a traditional classroom, that’s not to say it is entirely easy to wrap your brain around. There are a lot of misunderstandings out there about the 5E Model — what it is, how it should be used, and what types of materials are compatible. In this post, we are going to look at why we should be using the 5E Model and how we should be using it! If you’d like more guidance and support in transitioning your instruction to the new standards, check out the NGSS Your Science Class course and Science Teacher Tribe. Why The 5E? The 5E Model is designed to help students develop conceptual understanding in science. What is conceptual understanding? In their book Teaching for Conceptual Understanding in Science, Richard Konicek-Moran and Page Keeley describe conceptual understanding as the difference between baking a cake from scratch and making a cake from a packaged mix. When you make a cake from a box, you can follow the instructions, get the outcome you want, and not understand a single thing about what happened. When you bake a cake from scratch – no recipe here – you have to know the purpose of each ingredient. You need to understand how they interact — the difference between baking soda and baking powder, for example, and how each affects the flavor and texture. You need to know how much of each ingredient to add and the best way to add them, when and how to mix them, so on and so forth. You truly understand the whole process. It’s likely you could use your knowledge to make another type of dessert, too! You’re not limited to just spitting back the steps of baking a cake. We want our students to learn how to bake cakes from scratch. Ok, maybe not actually bake cakes (although that could be a fun chemistry phenomenon), but you get my point. We want our students to understand the various components of the content we teach, how they connect and interact, the cause and effect relationships, and why they matter. We want our students to be able to apply their understandings to similar situations, transferring their knowledge from one context to another. To do this, we need to transform our instruction. Traditional Instruction vs. NGSS Instruction Let’s take a look at a science example. Typically, by middle school, students have been taught the hydrologic cycle (aka water cycle). They may have drawn pictures of the processes involved or made fun models with glass jars and plastic wrap. They might be able to identify terms like evaporation, precipitation, and maybe even condensation. These are all pretty typical approaches to teaching the water cycle. That said, there’s a good chance those activities didn’t help them understand what’s actually happening. When given Page Keeley’s “Wet Jeans” probe (this is from one of her Uncovering Student Ideas in Science texts), students often reveal that they believe that water that evaporates goes to the clouds. It’s not surprising — our textbook models often indicate water evaporating from the ocean and moving to the sky, where it then becomes clouds and falls as rain or snow. Where does it really go? It simply moves into the air around us in the form of water vapor — invisible but always there! The same students who answered “it moves to the clouds” could very likely pass a test on the water cycle, correctly identifying the definition of evaporation. They could probably draw a model just like the ones they saw in their textbook. But their understanding of how it really works is flawed. Why does this matter? Why are we talking about conceptual understanding? Because the goal of the 5E Model is to guide students through conceptual change — moving from their flawed, alternative conceptions (or misconceptions) of phenomena to an accurate understanding of how the natural world works (as we understand it based on best-evidence now! It’s important to note that science is always changing…) So in order to understand the stages in the 5E Model and how they were designed to be implemented, you really have to understand what the goal of the model is. It’s not for teachers to dump information into students. That’s the old way of teaching. The goal of the 5E Model is to provide students with the right activities that lead them to their own “ah ha!” moments – that key point when their flawed conceptual understanding of a phenomenon changes – hopefully becoming more accurate!!! When You’re Implementing 5E Instruction… - First, and most importantly, remember that the 5E Model is NOT a lesson-planning framework, in the sense that each day students enter your class and participate in a lesson. The 5E Model is used to design instructional sequences — instruction that occurs over many class periods. - Remember that not every stage requires a full class period, and it’s not uncommon for some stages to require several. - Lastly, remember that the 5E Model is not truly a linear approach. While there are five “stages” which may seem like steps, in reality, each instructional sequence will take a varied path through the stages depending on the content and student needs. Looking For More? If you’re serious about transitioning your curriculum and instruction to the NGSS, check out the NGSS Your Science Class course available at the Science Teacher Tribe. Join our community to get the 12 module course with video workshops, audio tracks, ready-to-use resources, and a growing library of NGSS-aligned sample lessons and activities, plus personal support and guidance.
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If it doesn’t kill me, it makes me stronger By Harry de Jonge The title of this piece did not literally come out of Fitness Bikini athlete Yana, but it did come to mind immediately after I hung up the phone after a short interview. If, like me, you have been involved in sports for over 40 years, you know that almost everyone experiences his or her preparation as terribly difficult, but when you see what Yana experienced in a short time while she still achieved incredible sports performances, you can’t help but take most people who had it “so hard” with a grain of salt. Yana comes from Ukraine and then you immediately understand that she is currently having a hard time. Her country is being bombed by the Russian army, many family members are in mortal danger and how that war will develop is still a question mark for everyone. But this misery isn’t the only thing that has happened to Yana over the past few years, the years when she was performing so incredibly! Yana graduated from the medical university in western Ukraine and came to the Netherlands four and a half years ago to explore the possibilities here. Her mother already lived and worked in the Netherlands. Finding work in the medical sector was of course difficult due to, among other things, the language barrier, which is why Yana threw her heart and soul into sports. “I noticed that the Dutch are a fit people. Everyone cycles here all year round, something that was not possible in Ukraine because of the long harsh winters. I was already sporty, I danced a lot and I was a choreographer and I could also sometimes be found at the gym. But it was only here in the Netherlands that I started to approach the latter more professionally.” Yana just lived here and had to go back to Ukraine to get the necessary paperwork in order. She decided to enter a beginners competition and, to her own surprise, reached the final. Yana immediately had a taste for it and once back in Amsterdam she wanted to participate in a contest again. She found a trainer to help her (Steven from Beyond Fitness) and together they chose the 2019 JBC as their first goal. Yana won her class and also became overall winner bikini fitness! She persevered and registered for the Open Rotterdam, a contest at B-level. During the preparation, disaster struck. Yana’s stepfather crashed in a helicopter and she was plunged into deep mourning. Despite this misery, Yana won her class again and yes, again the overall! She advanced to the highest national level and competed in the N.K. As if it were the most natural thing in the world, Yana won her class again and yes, the overall. Yana took the goblet home and had an image of a helicopter engraved on it. She dedicated the victory to her stepfather Jordan, something that means a lot to her. Training was put on a slightly lower plan, Yana had a lot to process and just when she wanted to pick it up again, the world was flooded by the corona crisis and training became almost impossible for Yana. Nevertheless, she took part in the Arnold Classic Europe in Spain where she finished fourth! “However, I was not in optimal shape. I especially lost mass on my upper body,” she says. Slowly, the situation around covid improved and training went a bit better, until disaster struck again. In October, Yana’s husband collapsed in the middle of the street from a heart attack! Yana’s medical background came in very handy here and she managed to save his life through intervention. Fortunately, the father of her two bonus children and her main support and rock survived and has since recovered well. And then…yes, then the Russian army invaded her homeland! “It was like being in a bad movie,” Yana explains. “But the passion for the sport did not die, I kept my faith and knew that I would come out stronger in the end. I went to the European Championship anyway and became first in my class,” said the 1.62m tall athlete. “After this E.C. we looked at the competition calendar again. A contest in the Czech Republic came too early and there we saw mention of the Arnold Classic in South Africa. My husband said in a spontaneous mood, “That’s where we’re going!” It turned out to be a great experience. It was beautiful. Due to the covid, the organization had set up tents everywhere. It wasn’t as busy as the AC Europe, the background was magical and I met so many nice people.” Yana won her class again and the organization invited her to join the professionals afterwards and Yana did that again with success because a fourth place in a first professional appearance is of course unbelievably good. I did this interview on June 15th and Yana told me that she will participate again this weekend in Luxembourg at the Diamond Cup. Still with the amateurs, because she will not participate in the pro circuit until 2023. “I need more mass to be successful with the professionals,” explains Yana. Yana is currently coached by Oksana Brygidir, a Ukrainian IFBB pro-elite athlete with a huge track record. Yana currently works as a personal trainer in Amsterdam. “I am very worried about the situation in Ukraine and if there are bombings like a few days ago again on the place where I come from, I will not be able to train properly.” Well, I understand that all too well and when I finished the conversation I just thought, wow, what some people have to go through. But it seems that Yana is only getting stronger!
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You are here Building a Feminist Internet Building a Feminist Internet How does ensuring the safety of women online help break down gender barriers in technology? Jac sm Kee discusses various ways that the Association for Progressive Communication’s (APC) Women’s Rights Programme have addressed public policy on women in technology. You have been deeply involved in various initiatives in Malaysia and worldwide related to the intersections of human rights, media, technology, and identity – especially around gender, sexuality, ethnicity, and religion. What sparked you into doing this kind of work, especially with regards to technology? I see the increasing prevalence and emphasis of the Internet in all aspects of our lives. From falling in love to demanding accountability from our government, it’s becoming part of the texture of our everyday social, political, economic, and cultural life. It’s not just an inert tool that we wield when we have access to it, but a space where things happen, where identities are constructed, norms reified or disrupted, action and activities undertaken. As such, it cannot help but be a space of intersectionality where many things collide and connect. Gender, sexuality, ethnicity, and religion are some of the most significant markers of power and identities, especially for me, as a feminist from Malaysia. I see the transformative potential of the Internet to enable more people, especially those with little access to other kinds of “public” spaces because of inequality and discrimination, to engage with the negotiation of these markers – what they mean, the values attached and related power relations. You currently head up the Women’s Rights Programme with the Association of Progressive Communication (APC). What does the APC do? How does the Women’s Rights Programme fit? The Association for Progressive Communications is one of the first organizations to look at the connection between access to the Internet and social justice. We work with organizations and partners in different parts of the world to promote easy and affordable access to a free and open Internet for all people to improve their lives and create a more just world. APC’s Women’s Rights Programme (WRP) began in 1993 as a network of women throughout the world committed to advancing information and communication technology (ICT) for women’s empowerment. It began as a group of 175 women, techies, and gender and ICT advocates from 35 countries, and is now one of two core programmatic area within APC. The programme focuses on women’s rights and empowerment on the Internet and related ICTs. We build the capacity of women’s movements, activists, and organizations to use the Internet strategically and safely in their work to advance women’s rights, while also engaging the Internet as a feminist, political space. We also work to build connections between women’s rights movements and Internet rights and policy advocates, to inform and influence decisions around technology with women’s priorities and realities. And we aim to influence expectations and conversations around gender and technology through research, content creation, and policy. We recognize how technology can reflect, augment, and amplify power relations. We work to apply their tremendous transformative capacity to strengthen feminist movements and advance women’s rights. At what point in your career did you see the connection between gender and technology? It was at one of the earliest trainings I attended (which coincidentally, was organized by APC Women’s Rights Programme) for women’s rights organizations on strategic use of ICTs. One of the trainers, Pi Villanueva, gave us a presentation on the historical development of the Internet and computing. She talked about the forgotten women developers like Ada Lovelace and Grace Hopper, and I realized for the first time that the Internet was not neutral, and it was critically political and gendered just like any other dimension of our life. My mind was blown. And since then, I have made this one of my core areas of activism. What does a “feminist Internet” look like to you? There isn’t a short answer, but to start, a feminist Internet is one where everyone has universal, equal and meaningful access to an open and transformative Internet to enable the exercise of all of our rights, to play, to create, to form communities, to organize for change, in freedom and pleasure. There have been a number of high-profile cases of online harassment and violence against women in the last few months, such as #GamerGate and the harassment of Anita Sarkeesian. Your work with APC is directly related to digital privacy and safety against online violence against women. What sort of work do you believe needs to happen to create better safe spaces for women to really be able to create, transform, and express themselves online? Just like the global, sustained effort to end violence against women broadly, this takes multiple, concerted strategies by different actors. It starts with increasing meaningful access and empowering the capacity of women and girls to use the Internet, not to feel wary of it, or somehow less technically adept or “naturally belonging” in this field, which feeds into a gendered culture of technology that acts as a backdrop to online violence against women. We also need to strengthen the capacity of women’s rights organizations who do such great work on ending violence against women to understand, analyze, and integrate how the Internet impacts on their work and strategies. Governments need to include online violence against women as part of their plans to end violence against women as a whole, and see this as a larger problem of a barrier for women and girls to exercise the full range of their human rights. Social media companies, which is where much of the online violence against women takes place, need to take proactive steps to ensure their space does not enable these acts. This includes making a clear and strong commitment on human rights, being transparent about their policies and how they are being carried out, providing adequate training to their staff on this issue, and importantly, involving women’s movements and activists from different parts of the world in the discussion. The hardest part is in changing the gendered culture of technology. Online violence against women is an overt expression of the gender discrimination and inequality that exists offline. Online, it becomes amplified. The most important way to shift this is to enable women and girls to engage with the Internet at all levels – from use, creation, and development to the imagination of what it should and can be. Instead of starting from the perspective of risk and danger, we’d like to begin the work from the standpoint of strengthening the resilience of women’s movements. It seems that there is more regulation online with regards to gender and sexuality, compared to other kinds of online regulation such as regulation against violence. Recently there have been efforts by Facebook and Google to regulate identity. What is your take on the regulation of identity with regards to technology? There is definitely a tendency towards regulation of sexual expression (even when it is done freely and with choice and consent), while at the same time there is a tendency to ignore sexual violence. The kinds of sexuality and gender identities that conform more to the norm are rewarded (for example, sexualized comments towards women are condoned and ignored), while those which are further away from it are censored (for example, censorship of LGBT people or abortion information in some countries). This was something that we at APC spent some time looking at as part of our EROTICS project (Exploratory Research on Sexuality and the Internet). We found that the ability to be anonymous is an important part of safety and the exercise of autonomy, especially for people who may be at risk, such as women who are in situations of domestic violence or queer and trans* people who go online searching for information, community, and support. One of the biggest transformative powers of the Internet was the potential to be free from having their identity regulated, including gender identity and sexuality. However, there is an increasing push toward internet users having singular identities that are as closely linked to the person as possible, especially by social media and other Internet companies with great reach, such as Google. This is fuelled, in part, by an economic model of the Internet that is based on the collection, aggregation, and commodification of personal data. So the more I can pin you down, the more I can make connections between what you do online, your social universe, your interests, and so on, and the more I can turn this into a profitable information. Even elections are starting to rely on such information. This trend is also communicated to users through the celebration of the individual on social media platforms, which is a very real part of Internet culture today. As feminists who are engaged and working on the Internet as part of our political space and agenda, it’s really something to actively resist and challenge, to return the Internet into its more open and public characteristics. How do you think diversity and intersectionality affect women’s involvement in online space? For something like the Internet, which is still deeply imbued with disparity of access and participation in terms of location, gender, and other forms of capacities, it is absolutely critical for voices, histories, experiences, creativity, and imagination from diverse parts of the world to be surfaced and amplified. This is at the heart of the disruptive nature of the Internet – that it provides more people with the capacity and space to tell their stories and create change with less barriers than other forms of public and political spaces. And in doing so, it can transform the kinds of values and norms that structure our lives. What have been some of the more amazing and notable achievements and impacts you have seen with your work in the APC? I think one would have to be the work around violence against women and the Take Back the Tech! campaign. When we begun work on this in 2005, there was barely any discussion on this issue, even though I knew that things like sexual harassment over SMS was a matter of course. It just wasn’t being recognized as part of the issue of violence against women largely. We had no budget: I remember working on it with a small team of people over many late nights debating on how to make this a radical, feminist, and truly collectively-owned initiative, which could turn the whole conversation around gender, technology, and violence against women on its head. The first site was built in HTML! We wanted to engage the Internet content-creating community, and especially women and girls, to organize and have fun with using and experimenting with new platforms and tools for activism on this issue. It really took off, and we had great collaborators like Retome a Tecnologia, started by two feminists in Brazil, and Women’sNet in South Africa, which localized the campaign and organized all kinds of creative actions with their community. The campaign has since grown and even won several awards – honorary mentions in the Prix Ars electronica for digital community, and very recently, the first ITU Gender Equality and Mainstreaming award for building confidence and reducing threats to women’s safety online. What does the future hold for the APC, your work, and the feminist Internet? If women and girls were able to freely express and advocate for themselves online without harm, how will the world be different? One of the exciting things we developed this year is the Feminist Principles of the Internet. Together with activists, writers and thinkers from feminist, Internet rights, queer and women’s rights movements, we were able to articulate a set of principles and ideas that would frame a feminist Internet. As a living document, we hope to use it as a way to further engage with broader women’s movement. Women’s movements are usually so good at saying what we don’t want; this document is especially valuable because it clearly expresses what we do want. Instead of starting from the perspective of risk and danger, we’d like to begin the work from the standpoint of strengthening the resilience of women’s movements. To regain our control over how we can use, shape, and define what technology means for us in our lives, and how it can create spaces for transformation and imagination of a radical world where gender, sexuality, and identities are not causes for discrimination and violence, but for celebration, equality, and collective and shared power. About The Author Jac sm Kee is a feminist activist, poet, and writer. She is the Manager of the Association for Progressive Communications Women’s Rights Programme. Her areas of focus include Internet governance, human rights and freedoms, sexuality, women’s rights, violence against women and the creative and strategic use of communications technologies for movement building and inclusive political engagement. Jac is also co-founder of Knowledge & Rights with Young People through Safer Spaces (KRYSS), an organization working with young people on the issue of sexual rights in Malaysia. She is currently serving as a board member for the Association of Women’s Rights in Development (AWID), the New York chapter of Creating Resources for Empowerment and Action (CREA NY) and co-director of Centre for Independent Journalism, Malaysia (CIJ).
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On Thursday, the official website for The Executioner and Her Way of Life (Shokei Shōjo no Virgin Road) anime revealed the main staff, teaser visual and character designs. They also announced that the anime would premiere in 2022. The anime is adapted from Mato Satō and Nilitsu’s light novel series of the same name. |Sound Director||Jin Aketagawa| Menou (Iori Saeki), the young executioner girl who has exceptional magical talent Akari (Moeka Kahara), the lost one, who is affectionate and easy-going. The Executioner and Her Way of Life is licensed by Yen Press for North America in English under the title “Virgin Road”, and it describes the story: The Lost Ones are wanderers who come here from a distant world known as “Japan.” No one knows how or why they leave their homes. The only thing that is certain is that they bring disaster and calamity. The duty of exterminating them without remorse falls to Menou, a young Executioner. When she meets Akari, it seems like just another job…until she discovers it’s impossible to kill this girl! And when Menou begins to search for a way to defeat this immortality, Akari is more than happy to tag along! So begins a journey that will change Menou forever… In addition to being an intriguing addition to the ever popular isekai genre of light novels, Virgin Road is an intriguing release due to the fact that it includes elements not commonly seen in light novels released in English—a female protagonist and a yuri storyline.
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Gone are the days when you could waltz into a video store, rent a VHS, and return it the next day. Streaming services have gone to battle with the local movie stores, and coming across a family-owned shop is about as common as finding a two dollar bill. These relics of the past aren’t all gone, however. Austin’s I Luv Video has been going strong for over 30 years. From the famous to the obscure, you’ll find something to pique your interest at I Luv Video. The oldest video store in America is right here in Austin, and you’ll definitely want to visit.
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TGIF, Agents of Impact! We’re taking a Brief break for the Labor Day holiday here in the U.S. We’ll be back on the case and in your inbox on Tuesday, Sept. 7. 👏 The Call: Capitalism Reimagined. Long term stewardship. Investment guardrails. Shareholder democracy. Internalizing externalities. The Shareholder Commons’ Sara Murphy, Engine No. 1’s Michael O’Leary, Illinois State Treasurer Michael Frerichs and other Agents of Impact will join ImpactAlpha and Omidyar Network to talk tactics for mitigating systemic risks, Tuesday, Sept. 14 at 10am PT / 1pm ET / 6pm London. RSVP now. 🎧 Impact Briefing. On this week’s podcast, host Brian Walsh is joined by ImpactAlpha’s Dennis Price and Amy Cortese to talk “beta stewardship” and hurricane resilience. And we meet Sunwealth’s Jessica Brooks, this week’s Agent of Impact. Plus, the headlines. Tune in, share and follow us on Apple, Spotify or wherever you listen. Sponsored by Morgan Stanley Investors plug into the electrification supercycle. What’s a unique way to play the popular electrification theme? A new angle for investors. The Week’s Agent of Impact Jessica Brooks, Sunwealth. On her neighborhood strolls, Jessica Brooks sees schools, churches, apartment buildings – and unused rooftops. Such “infill” spaces represent a trillion-dollar solar energy opportunity to generate a quarter of the U.S.’s energy needs. “Yet they’re totally overlooked by the big investors,” says Brooks, who is the chief development officer at Sunwealth. The Cambridge, Mass.-based lender finances community-scale solar projects that cut occupants’ energy bills and share the benefits of clean energy and next-economy jobs with low-income and underserved communities. The 1.8-megawatt solar array Sunwealth is installing on the Queensbridge Houses in New York will generate lease revenue for the New York City Housing Authority, discounted energy for low-income households, and green jobs for local residents. Call it “solar justice.’” Brooks started her career at BlueHub Capital, a Boston-based community development financial institution. Sunwealth, founded in 2014 by Jon Abe, applies that same focus on underserved communities to climate finance. Brooks joined up in 2018. “It’s not just one of the biggest business opportunities of our generation, it’s one of the biggest economic-justice opportunities,” she says. Sunwealth has invested $65 million in 450 projects in 14 states, as customers and communities look to combat climate change and increase local resilience. “Nonprofits, the local food bank… these are all groups that pay their electric bill and are great credit risks,” she says. Brooks contributed a well-read essay this week about her personal investment philosophy. “Our communities are ripe with opportunity – both financial and impact,” she says, “if you adjust your lens.” – Amy Cortese - Share Jessica Brooks’ Agent of Impact story and like it on Instagram. - Walking the talk. Brooks details her personal investment portfolio in “Investing in a better world for all of our kids,” the latest installment in our series with Confluence Philanthropy. The Week’s Big 6 1. New Orleans’ resilience force (podcast)… Nearly a million people in Louisiana are still without power five days after Hurricane Ida lashed the state. Local mutual aid organizations and essential workers already are knee-deep in the recovery. Resilience Force, founded by Saket Soni, wants to ensure that recovery efforts redress inequalities, rather than exacerbate them. “We have to make it a national project to build resilient people, surround them with the abundant resources they need, have their backs, build and fund their safety net, provide them jobs,” Soni says on the latest episode of The Reconstruction. Read on and tune in. 2. …and resilient infrastructure opportunities. Decentralized, renewable microgrids are built to operate independently of the grid. Microgrids are “effectively an insurance plan” against outages from hurricanes, freezes and wildfires, says Spring Lane Capital’s Rob Day, who urges investors to “challenge the developers more about resiliency-based business models.” Plug in. 3. Alpha is alright. Beta is better. Increasing antimicrobial resistance poses risks to portfolios on par with climate change. Tackling systemic risks with “beta stewardship” can hold companies to account for such negative externalities and protect the long-term health of the system as a whole. “It’s a misunderstanding of fiduciary duty when investors focus entirely on the outperformance of a single stock against a benchmark, instead of the health of the benchmark itself,” says The Shareholder Commons’ Sara Murphy. Level up. - Capitalism Reimagined. Join the conversation on Agents of Impact Call No. 30, Tuesday, Sept. 14. 4. Energy access relief. With razor-thin margins in tough markets, off-grid solar and other energy access companies took a big revenue hit last year as COVID disrupted projects and supply chains. The Energy Access Relief Fund, launched by Acumen with CDC Group, raised $68 million to make loans to companies that otherwise would have to downsize or shut down. A first-loss grant cushion from private foundations and government donors, along with a portfolio guarantee from the Swedish government, secured a $30 million investment from the Green Climate Fund. Shine on. 5. Sustainable public equity offering. Allbirds is famous for its stylish shoes, made from materials like wool and castor bean oil. The shoe company is looking to get recognized for its ESG performance in its initial public offering. The public-benefit corporation and certified B Corp aims to zero-out its carbon footprint by 2030. Hold ‘em accountable. 6. Centering civil rights. Community development financial institutions, or CDFIs, aren’t immune to discriminatory lending practices, argue Appalachian Community Capital’s Donna Gambrell and Pacific Community Ventures’ Bulbul Gupta in a guest post. ”It is up to us to meet the moment, to internalize the goal of closing the racial wealth gap, and make sure our missions and how we deploy capital reflect that.” Hear them out. The Week’s Dealflow Spotlight: Health and wellbeing. The pandemic created an opportunity to nudge the healthcare sector “towards a more digital, consumer-focused, and accessible reality,” says Heather Fernandez, founder of Solv Health, which raised $45 million to connect Americans to urgent care providers. The company says its app helps 11 million patients per month find same-day care providers, schedule consultations and complete paperwork online. Acrew Capital and Corner Ventures backed Solv’s Series C round. - The week’s health tech. SJF Ventures leads Ellipsis Health’s $26 million round to help individuals and care providers manage mental health conditions… Elda Health in Bangalore raises $1.5 million for its digital women’s health platform… City Light Capital, Kapor Capital and Acumen back addiction treatment app Affect Therapeutics’ $6 million round. - Access to care. Penn Medicine and Wharton Social Impact Initiative launch a $5 million Fund for Health to address social determinants of health for underserved Philadelphians… Minneapolis-based Joshin clinches $3 million to help people with special needs find caregivers… MeetCaregivers raises $1 million to match seniors with home health aides, nurse’s assistants and other caregivers. Digitizing small businesses. Logistics company RubanBridge secures early funding to bring products and jobs to rural India… Bangalore’s Kirana247 raised $1 million to expand inventory delivery services for thousands of urban kiranas… Khatabook and Bazaar raise financing to digitize small businesses in India and Pakistan… Egypt’s small business digitization and logistics company MaxAB acquires Moroccan peer WaystoCap. Low-carbon transition. Energy Vault secures $100 million for gravity energy storage… BlackRock takes a stake in JOLT to accelerate electric vehicle adoption in Australia… Carbon Equity secures €1.2 million to lower minimums for private climate investing… Helix Power launched an equity crowdfunding campaign on SeedInvest for its flywheel-based kinetic energy storage system. Inclusive communities. Silicon Valley Bank backs National Equity Fund to create affordable rental housing in California… The International Finance Corp. commits $50 million to Letshego to finance affordable housing in Namibia… CEI-Boulos Capital Management’s Opportunity Zone impact fund makes a $3 million equity investment in an affordable student housing project for low-income students. Agrifood investing. Bamboo Capital’s ABC Fund invests $4.7 million to support lending for Bolivia’s smallholder farmers… Plantible scores $21.5 million for duckweed-based protein… NBA star Chris Paul and Jay-Z back Black-owned Misha’s Kind Foods’ $3 million raise to make plant-based cheese. Resilient infrastructure. Breakthrough Energy Ventures backs Reactive Technologies to help network operators and energy storage developers assess grid stability… LevelTen Energy secures $35 million to build renewable transaction infrastructure for clean energy advisors, buyers and sellers. Returns on inclusion. Achieve Partners acquires Metmox to create apprenticeships for cybersecurity. Western Alliance Bancorp. invests $9 million in Clearinghouse CDFI’s targeted $250 million FVLCRUM Fund. Impact milestone. Australia’s Giant Leap raises $15 million for second impact fund. The Week’s Talent Christina Travers, ex- of Working Solutions, is named CFO of the Local Initiatives Support Corp. Travers, who formerly served as LISC’s treasurer, replaces Michael Hearne, who is retiring… Scott Love, ex- of Louisville Forward, will lead the Local Initiatives Support Corp.’s Louisville office… Kavita Nandini Ramdas, ex- of the Open Society Foundations, will be the new president and CEO of The Nathan Cummings Foundation. Ashleyn Przedwiecki, Monica Jones, Chou Moua and Katelyn Retterath Martin are among nine social entrepreneurs selected for the FINNOVATION Lab fellowship… Ann Mei Chang, ex- of USAID and Mercy Corps, will become CEO of Candid, which was formed by the 2019 merger of Guidestar and Foundation Center… Anne Finucane, who led Bank of America’s ESG and sustainable finance efforts, will retire as vice chairman. The Week’s Jobs Kiva is looking for a director of strategic investments… Refugee Investment Network seeks an Africa director… impak Finance is hiring an impact analyst in Montreal… Avesta Fund is looking for an investment manager for a new climate and diversity fund… J.P. Morgan-owned OpenInvest is recruiting an ESG product associate in San Francisco… Value Reporting Foundation is looking for analysts. Prime Coalition is looking for a partnerships associate in San Francisco… Rockefeller Foundation seeks a manager of impact investment in New York… Emerson Collective is hiring a portfolio manager for its “culture council” in Palo Alto… Silicon Valley Community Foundation is looking for a senior associate of investments in Mountain View, Calif… NatureVest is recruiting a portfolio coordinator of disability solutions in Washington, D.C. Sarona Asset Management is hiring a senior impact associate… The Nature Conservancy is recruiting a deputy managing director of forest and carbon investing… The U.S. International Development Finance Corp. is hiring senior impact management and monitoring specialists in climate and infrastructure and financial institutions… Villgro Innovations Foundation is looking for a manager of climate action in Bangalore… Aidentifi seeks a head of sustainability and impact in Singapore. That’s a wrap. Have a wonderful weekend. – Sept. 3, 2021
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Fast Retailing unveils new Lifewear-based eco business strategy, reports Uniqlo sales Fast Retailing announced on Thursday that it’s “advancing” its LifeWear concept and has “formulated Fiscal 2030 Targets and an Action Plan for core aspects of sustainability”. And it added that “the entire Fast Retailing Group, based on the LifeWear concept, will accelerate its transition to a new business model encompassing both sustainability and business growth.” The strategy is underpinned by ethics, diversity, inclusion, carbon-neutrality, zero waste, traceability and transparency. It said that Lifewear is all about “everyday clothing, designed to make everyone's life better — to create apparel that not only emphasises quality, design, and price, but also meets the definition of ‘good clothing’ from the standpoint of the environment, people, and society”. So what’s actually happening now? In conjunction with the objective of the Ariake Project (“to make and sell only apparel that customers truly want”) that it launched with Google in 2017, it will “emphasise care for the environment in all processes, from manufacturing to transport and sales, sharply reducing greenhouse gas emissions and waste to establish a production process with a light environmental impact”. At the same time, there will be a big focus on safeguarding human rights in all processes, “building a supply chain that allows customers to purchase products with trust”. It will also develop new reuse and recycling services and technologies to extend the life and utility of LifeWear post-purchase. And it’s extending its worldwide initiatives for social contribution and diversity through the apparel business. Fast Retailing Group Senior Executive Officer, Koji Yanai, said of all this: “Providing apparel that customers will cherish for a long time has been the aim of our business for many years. With environmental problems and other serious global issues becoming increasingly evident, we have further advanced our philosophy, and are pursuing measures to show the world a completely new way for clothes to be, while contributing to the realisation of a sustainable society.” Practical targets include — among others — focusing on zero waste by reducing, replacing, re-using, and recycling materials used in the process of delivering clothes to customers; achieving carbon-neutrality by 2050; reducing greenhouse gas emissions by 90% by 2030; cutting store electricity consumption; and developing new highly energy-efficient store formats, with an aim to launch a prototype store during 2023. It’s also aiming to increase the proportion of recycled materials to around 50% by 2030 and is expanding its introduction of materials that “place a lower burden on the environment, starting with synthetic fibres such as rayon and nylon”. The new strategy runs throughout the group, but most consumers are likely to encounter it when they buy from its biggest brand, Uniqlo. And on the same day as the firm released the news, it also reported its Japanese Uniqlo monthly sales. The operation saw sales falling again in November with a 4.6% comparable drop and a total sales fall of 5.1%. Both figures included online sales. The company said that while its annual Uniqlo anniversary sale and sales of collaborative products proved strong, same-store sales declined after warmer-than-usual temperatures in the first half of the month stifled sales of cold-weather clothing. The weather is a constant issue for the business as many of its simple basics are heavily dependent on the right kind of weather, be it sunshine in the summer or cool temperatures later in the year. Customer numbers were above the average for the year to date in November, but the average purchase per customer lagged the rest of the year. Copyright © 2023 FashionNetwork.com All rights reserved.
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How to convert 3948 inch to millimeters? |3948 in *||25.4 mm||= 100279.2 mm| A common question is How many inch in 3948 millimeter? And the answer is 155.433070866 in in 3948 mm. Likewise the question how many millimeter in 3948 inch has the answer of 100279.2 mm in 3948 in. How much are 3948 inches in millimeters? 3948 inches equal 100279.2 millimeters (3948in = 100279.2mm). Converting 3948 in to mm is easy. Simply use our calculator above, or apply the formula to change the length 3948 in to mm. What is 3948 inches in mm? To convert 3948 in to mm multiply the length in inches by 25.4. The 3948 in in mm formula is [mm] = 3948 * 25.4. Thus, for 3948 inches in millimeter we get 100279.2 mm. 3948 in in mm, 3948 Inch to Millimeters, 3948 Inches to Millimeter, 3948 Inches to mm, 3948 Inch in Millimeter, 3948 in to Millimeter, 3948 in in Millimeters,
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Radisson Blu Kochi Radisson Blu is a 45-minute drive from Cochin International Airport and an hour’s drive from Cherai Beach. Welcome to Radisson Blu Kochi – a luxury hotel located in the heart of the vibrant city of Kochi. Our hotel is situated at S.A Road, Elamkulam Junction, Kadavantara, Ernakulam, just a stone's throw away from some of the city's most popular landmarks, including the famous Lulu Mall and the scenic Marine Drive. At Radisson Blu Kochi, we pride ourselves on offering our guests a world-class hospitality experience that combines the best of luxury, comfort, and convenience. Whether you're traveling for business or leisure, our hotel is the perfect base from which to explore the city. Our hotel features a range of well-appointed rooms and suites, each designed to cater to the needs of modern travelers. From deluxe rooms to executive suites, each room is equipped with modern amenities such as high-speed internet access, flat-screen TVs, and comfortable beds to ensure that your stay is as comfortable as possible. We also offer a range of on-site dining options, including our signature restaurant – The Great Kabab Factory – which serves up a delectable selection of Indian kababs and other dishes. Our other dining options include the all-day dining restaurant, The Market, and the trendy lounge bar, KTiz. When it comes to events and conferences, Radisson Blu Kochi is the perfect choice. With over 13,000 square feet of event space, including a grand ballroom and multiple meeting rooms, our hotel is equipped to handle everything from large corporate events to intimate social gatherings. Other facilities at our hotel include a well-equipped fitness center, a rooftop swimming pool, and a spa that offers a range of relaxing treatments. So whether you're visiting Kochi for business or leisure, make Radisson Blu Kochi your home away from home. Book your stay today and experience the very best of Kerala hospitality. S.A Road, Elamkulam Junction, Kadavantara, Ernakulam, 682020 Tour2X is a global corporate accommodation provider, specialized in serviced apartments for extended stays. We provide serviced apartments/hotels/apart hotels internationally in over 5500 cities and 170 countries. We deliver highly optimized,premium stay experiences at unbeatable prices. With our cutting-edge technology platform, you can have access to our global network of 32000+ apartments, competitive pricing, employee tracking system, custom reporting and 24/7 prioritized customer support. If you are a frequent business traveler, Tour2X is one stop solution for all your accommodation needs. We help you find the best-suited accommodations in no time. "Quickly Discover Your Perfect Accommodation with Our Assistance" Visit https://Tour2X.com to know more about our product and services. Dedicated team for your business to make sure you receive best service. 30 point checklist to ensure the safety, security and amenities of an apartment. With our strong business association with furnished apartments and premium hotels, we assure you savings of 10-15% or more at 82000+ properties globally. Access all the deals promoted by our hospitality partners. Looking for recommendation? Set up a call with our Advisor.
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2023-09-27T10:46:13Z
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The Jamia Students are doing wonders in the field of science and technology. The Jamia students of Baitusalam Talagang have dominated the robotic events, ROBOCUST 2022, at Capital University of Science and Technology, beating students from other universities. Baitusalam Talagang students break society’s stereotype that Madrassa students cannot be successful in the sciences and the tech field. They won first place in three different robotics competitions at RoboCust. RoboCust 2022 was a competition for technological innovation and robotics in which many universities participated. Source: Baitusalam Talagang
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2023-09-27T10:47:50Z
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2GIS showed on the map why #stayhome is important 2GIS showed possible scenarios of virus spreading around the city. The simulation is available at covid.2gis.ae. It demonstrates how an infection similar to coronavirus can spread and how to slow it down. «This is a model of social interaction in the city. It makes clear why a conscious attitude to a pandemic is everyone’s responsibility and proves that together we can confront the virus. Staying at home if possible, self-isolating if you feel unwell, washing your hands more often, keeping a social distance in the office and public places — each decision affects how fast the virus spreads. Social distance today also means taking care of those who may need medical assistance, and it helps to reduce the potential pressure on hospitals,» — Pavel Mochalkin, 2GIS CEO. Disclaimer: the graphs should not be interpreted as an actual forecast of the infection spread. Real dynamics cannot be estimated by them.
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2023-09-27T12:20:19Z
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Overview of different infrastructure contractual models Being contractual model agnostic is critical to improving the delivery of infrastructure. The table below provides a menu of infrastructure contractual models, categorised by the ultimate functions the models deliver. These functions cover the main activities to deliver an infrastructure project; design, construction, operations, and maintenance. Each model has been defined along with identification of alternative variants or names that can relate better with known categories in some jurisdictions. Finally, it provides a representation for the common aspects within each contractual model but is not considered absolute due to the ways that parts of each model may be combined by the procuring agency. Collaboration or co-operation are considered pertinent to all models with the contract form influencing these resulting behaviors. This needs to be a procurement agency priority in order to deliver the benefit of working in partnership with the private sector in order to deliver innovation, mitigate risks and deliver reliable outcomes. Is there a model or variant we’ve missed? Let us know here. This table has been developed with input from the World Bank and has drawn from definitions of PPPs developed by the World Bank PPIAF and APMG Certification Program. The contractual models function as classified below are: Build or Construct Only, Design & Build, PPP, Privatisation, and Regulated Asset Base.
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2023-09-27T12:17:56Z
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The Food and Beverage Innovation Centre (FBIC) will be the core facility for the BC Ministry of Agriculture’s BC Food Hub Network, which is intended to improve local food chains for food security and human welfare and foster growth and innovation in the processing sector through improved industry access to facilities, equipment, technology, technical services and business supports. The project is key for the Faculty of Land and Food Systems (L&FS), supporting the Faculty’s continuing leadership in food technology research. The new facility is designed to provide functional and flexible spaces that serve current functions and can be changed over time to accommodate future equipment, technologies and processes. The FBIC will be used for teaching and laboratory activities in food processing & engineering courses, and will be used to incorporate new laboratory demonstrations and activities for students. The facility will allow successful graduates of the program to learn related hands-on applications of the latest technologies for producing nutritious, safe and convenient food products. The FBIC will also be a hub for collaboration with Musqueam with a goal to extend awareness of the benefits of traditional Musqueam foods and medicines in order to ensure sustainability of these important crops.
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https://infrastructuredevelopment.ubc.ca/projects/food-and-beverage-innovation-centre/
2023-09-27T10:37:24Z
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Spotted: Bike to Work Day volunteers cheering on participants Longtime Bike to Work Day volunteers Kevin and Bernadette (first and second from left) were joined by Menlo Park city employee Randy at the San Mateo Drive bike bridge this morning. The two volunteers said this was the fifth year in a row that they had manned an energizer station. Folks who decided to ride their bikes to work this morning will have to get home on their own energy. The stations are only open in the morning from 7:00 to 9:00 am.
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2023-09-27T12:01:43Z
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I have been searching for a bulletproof, non-bulky leather jacket for a while now as an individual who regularly conceal carries and appreciates the use of body armor in my every-day life. Innocent Armor has made it possible for citizens to maintain style and safety which is truly a hard balance to come by. Be sure to measure your chest and arms for the sizing and when in doubt, size up. I am a size 10, 5'10'', and a 36C in the chest and found the XL to be the most comfortable size for me. Thank you Innocent Armor! I’ve been looking for body armor for my wife to wear that doesn’t look like body armor… I’ve always felt that someone wearing armor in public is like open carrying, you’re advertising that you are protected and they’ll assume you’re probably carrying a gun. A friend referred me to Innocent Armor and I’m so glad they did. She absolutely loves it and I have a little more peace of mind that she’s protected when I’m not around. My wife loves It, very ellegant and casual at the same time! Absolutely appreciate the “Safety” forward thinking and creativity of this new concept lifestyle clothing line for men and women. Unfortunately we can not control the volatility of others, however we can be pro active in protecting ourselves as well our families. Innocent Armor is simply an amazing option for many that are Not law enforcement officers, that desire additional options of protection aside from legally carrying a fire arm everywhere. My fashionable favorites are the Leather Jacket and the Down Vest. Perfect wardrobe additions for casual & contemporary chic dressy attire with “Safety“ center mass protection!!! Highly recommended, and a great self love investment. Michelle Renee SF My family loves everything we got from them.
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2023-09-27T12:48:41Z
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Online dating has come with no warranties that basically we you will have a superb experience. You maybe chat with an interesting unfamiliar person, hope that your early dates go well, and then roll the dice in hopes your very first date should go bad. The probabilities are great that this will never be a successful primary date for any person. Online dating is fun and it is growing in popularity but there are some things which can help make your online dating sites experience more successful. One thing that can help to make your web dating experience more successful is usually making sure that you locate someone that uses the same online dating app that you do. If you use a no cost dating iphone app like Orkut or Bing! 360, it helps to ensure profound results to connect since you have many people using the same system. This is certainly an important a part of making your web dating knowledge a success. You would like to ensure that all your communication can be reliable and that you get good feedback to the first particular date. There are many undesirable goes online and you need to try to limit them whenever possible. An optimistic feedback makes it easier to prevent bad appointments if you already had a bad date. It can be hard to address tell in cases where someone may be a fake or perhaps not due to all the facades they put up on dating websites. Fake information can really prevent you coming from trying new comers or looking at different parts of the world. This is why it is so vital that you see profiles of folks that you may be interested in dating. Additionally to witnessing profiles, you must also go to online dating websites and show around. By doing this you will get an awareness of00 the online going out with experience plus the websites alone. Some singles do not value what other lonely hearts think of their online dating encounters, but other folks take this very seriously. It really is not important how various singles you may have on a website as long as you are honest on your own. If you only tell your self the truth, then you will have a far greater chance of producing a great initially date. The majority of people will not feel comfortable in order to way another solitary. Therefore , they will usually disassociate with doing this. You last thing you can do to make certain your initial date is known as a success is to go to a social networking feel like zoosk. This may audio ridiculous, but I have discovered some single’s that obtain a lot of visitors from using these types of social media sites including MySpace, Fb and twitter. These were able to apply these networking communities to get more focus for their initial date and create a superb opportunity for a second date. When you follow these pointers, you will definitely contain a great time online dating services and will have many great interactions in the future.
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https://inovasus.ibict.br/four-easy-tips-to-making-a-fantastic-first-day/
2023-09-27T11:03:06Z
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BARCELONA – On Tuesday, the Catalonia region board announced stricter water restrictions for 224 municipalities. The region is experiencing the most severe drought since rainfall records began in 1905. The measures affect up to 6 million inhabitants. The drought has been going on for 30 months. And, consequently, it is causing a lack of water in the internal basin of the Ter-Llobregat system. This provides water to Girona, Barcelona and the entire urban area of the Catalan capital, among others. However, the basin is now at 28% of its capacity. With this new phase, around 6 million people can no longer water their gardens. Municipalities are no longer allowed to water public green zones. Until now, that was still allowed two days a week. Furthermore, restrictions on agricultural irrigation will increase from 25 to 40%. In addition, other restrictions will follow. For domestic purposes, the government sets a maximum of 230 litres of water per person per day (currently 250 litres). This limitation will hardly be noticeable in practice because the daily average consumption in the community is approximately 117 litres. “In a situation of extreme gravity, we must act accordingly,” said Councilor Teresa Jordà in El País. If the drought continues in the coming months, the government will move to water restrictions after the summer. The Generalitat also approved a 12-article decree. El País was able to see it and writes that fines for non-compliance with the new rules can amount to a maximum of €150,000 for the most serious offences. The fine system will range from not providing the requested information to the Generalitat (such as data on water consumption) to exceeding established limits, such as watering fields without respecting the restrictions. According to the new decree, the fine is calculated on the basis of the degree of exceedance of the cubic meters consumed. An amount of €0.30 per cubic metre of excess will be applied. Seizure of private wells and reservoirs possible When the emergency phase (the most extreme phase) is declared, an amount of €0.60 per exceeded cubic metre is imposed as a fine. In addition, and this is one of the most important innovations contained in the decree, the Generalitat will also have a tool to seize private wells and other water reservoirs if the situation requires it.” On Sunday, the director of the Catalan Water Agency warned in El País that residents of Barcelona and the surrounding area can expect water restrictions by the end of 2023 due to the most severe drought of this century.
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https://inspain.news/water-restrictions-in-catalonia-affect-up-to-six-million-people/
2023-09-27T12:33:39Z
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To support shared understanding, learning, and growth, DAWI shares de-identified research tools with eligible individuals, institutions, and organizations. In 2019, we released preliminary findings from the first national survey of individuals in democratic workplaces across the U.S. Sponsored by DAWI and conducted in partnership with the University of Wisconsin-Madison, the Center on Wisconsin Strategy (COWS), Rutgers University School of Management and Labor Relations, and the U.S Federation of Worker Cooperatives (USFWC), All About the Workers presents high-quality baseline data about the workplace attitudes, experiences, and demographics of individuals who work at democratic worker-owned firms. Findings from this new data are informing DAWI and USFWC efforts to build the field, advocate for worker co-ops in the political arena, and serve grassroots members. This data is now being made available to researchers on an application basis. Researchers interested in learning more about the data set and application process should click below.
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2023-09-27T12:05:00Z
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There I was, back to the small Chinese village close to the Himalayas. The trip was tiresome because of the many hours of flight, airport wait time for connections and a final stretch by bus on the precarious road that wound around the mountain. That one trip was made worse because my luggage had been lost by the airline company. My complaint at the airport was fruitless and the company did not ensure it would be delivered to me, because the village was too distant and out of the way. I was left with my backpack, with my documents and a couple of changes of clothes I had taken with me, because of the lengthy journey. As soon as I arrived, I tried to get some sleep at the only hostel in town. In vain. I was so upset my head was spinning because of the many ideas and feelings that were overflowing inside my mind. The sun was yet to rise when I stood up and went to the pleasant home of Li Tzu, the Taoist master, where he received students from all parts of the world seeking his teaching of the ancient lessons of the Tao Te Ching. When I crossed the gate to the house, always open, I had a pleasant feeling. A perfume whose source I could not identify, whether from huge jasmine shrubs that surrounded the bonsai garden or from the many incenses scattered around the house filling the voids of silence and tranquility. Some dimly lit lanterns indicated the narrow and winding path that led to the veranda. Li Tzu had finished a solitary yoga practice and was happy to see me. Always polite, he invited me for tea. When I entered the kitchen, Midnight, the black cat who lived at the house, bristled and bolted out when he saw me. Embarrassed, I said that the docile cat probably did not recognize me after so long a time since I was last there. The Taoist master was not deceived: “Cats are too sensitive to energy. Violence scared him.” I objected by saying I was a peaceful guy, incapable of hitting anyone. Li Tzu explained in a tone that was typical of him, ranging between sweetness and firmness: “Everyone knows you have a peaceful disposition, Yoskhaz. However, you are not well. Violence does not lie only in rude words or harsh attitudes. Bear in mind that we generate energy. The primary vibrations originate from our ideas and emotions, which are invisible to the eyes and yet perceived and important, because they can unbalance a person and, at times, disarray the environment. Or even worse, they can become the seed of mistaken choices, because they are far from the love that should guide us.” He paused and added: “We must watch ourselves all the time.” While he was making a herbal infusion, I told him all that had happened and the misfortune of being without my luggage. I regretted not having my electric shaver, the loss of some shirts I really liked, and the Swiss army knife I inherited from my grandfather, in addition to other belongings. Li Tzu listened patiently to my narrative and, at the end, commented: “The Tao teaches that ‘I always have all that I need.’” He placed the cups on the table and said: “When we incorporate this idea, we become invincible in the face of the typical setbacks of existence.” He looked at me as if telling a secret and said: “Even though it may be quite inconvenient at first, don’t worry so much about the lost luggage. Try to concentrate on keeping your internal luggage in order. This is the one that should be kept always neat, to make the tools necessary to overcome life’s unavoidable problems available.” I asked what tools he was talking about. The Taoist master explained: “The virtues. They are the shield that protects and the wings that liberate.” I wanted to know from what the virtues would set me free. He explained: “From suffering. Suffering is an unnecessary violence we allow ourselves to undergo because we do not know all the strength and power we have.” I asked him to have empathy for me and put himself in my shoes. I added that anyone would be upset in my situation. Li Tzu said that it is just because he imagined himself in my condition that he had said that, and made a remark: “Putting myself in your shoes does not mean that I will think like you or have a discourse that will fuel your annoyance. Just because I see myself in your condition, I can give you a different gaze, my gaze. I foresee the possibility of pacifying the self, despite the conflicts of the world.” I asked him how that would be. He answered: “The Tao teaches us to learn from water.” I said that he was complicating things. Li Tzu smiled and said: “Water teaches us the virtue of adaptation. Adaptation is the mother of balance and daughter of harmony, two valuable virtues. Whenever the world sets you off balance, your attempts to adapt yourself to the new moment take you to some sort of transformation in the way you are and live. This is evolution. Together, the virtues take you to heaven.” I asked him to better explain. The Taoist master remained patient: “The water comes down the mountain and when it reaches the lake, it adjusts to its shores. When an opening occurs, the water runs through it, forming a creek that flows until it reaches a larger body of water. If there is a rock in the way, the water goes around it. If placed in a box, it takes its shape until it is used. When it is exposed to heat, it gets transformed into clouds and is disseminated as drops that fall from the sky far from there. Invariably it will reach the sea, from where it will return as rain which, when it falls on the mountain, will set off a new cycle of renewal. The water cleans, purifies, renews the life of where it passes and moves on. The water must be in motion because if it is stagnant it gets soiled and generates diseases.” He paused and then added: “The person who keeps regretting is like stagnant water.” I disagreed. I said that conformity was a plague of humankind and prevented its evolution. Li Tzu agreed with me: “Yes, but conformity is not the same as adaptation. The difference is precisely whether the water is still or in motion. To move does not mean to make noise or become violent. When water does that, it is destructive. It had been under intense pressure and ended up by overflowing its own limits.” He filled the cups with tea and said: “When we simply accommodate to an uncomfortable situation, we are like a dam that, little by little, gets its limit exhausted until it is breached, and the water destroys everything around. This is when we let bad feelings feed violent actions or make diseases symptomatic. For that not to happen, one must adapt to the new situation to get the perspective it provides; the possibility of a different way of thinking and a better way to move on. The power of life lies in the quiet waters that flow down the river from one bank to the other and are nourished by all that the banks may provide. Otherwise, if contained, the waters end up causing an explosion and violently destroying all around where they pass. Flexibility and resilience are characteristics of adaptation, because they allow the necessary mobility. Life demands motion; if we deny it, stagnation makes us explode in fury, sadness or pain.” I recalled that the destruction of old forms was an unremitting and necessary esoteric law. Li Tzu agreed once again: “Yes, oftentimes, destruction and chaos are necessary to give room to what is coming. But only what we are unable to renew is what must be destroyed. The difference between one and the other is translated as a path towards war or peace; in days of suffering or harmony.” I reasoned that many a time, conflict was necessary to leverage evolution. The Taoist master nodded: “This is true, but conflict is essential only when we refuse to learn the lesson that is suitable, to be and to live in a wise, loving way. The water becomes destructive if collected improperly. Feelings only overflow and turn into violence if dealt with mistakenly”. “Luggage being missed is common in the modern world. Although it is not desirable, it happens every day. Just like the many setbacks of existence. Trains are late, popcorn finishes before the film, romance fades, people say ‘no’ to us, money gets short, layoffs occur. Not always is the object of your desire available on a supermarket shelf or in life. And this is good. Otherwise, we will never take our eyes off the landscape. We would continue to be distracted with the many pleasures on the planet, and not be marveled by the wonders that exist inside us. The Path is not crossed on the outside, but inside the walker.” He took a sip of tea and continued: “When you become aware that you, and everybody else, have absolutely all that you need, you will be enveloped by a sense of completeness. Never again you will feel hopeless. You will always find a way out, there will always be a good lesson to learn. Hence, water will renew the life it finds on its way”. I disagreed once again. I said that his discourse was quite agreeable, but not practical. There were situations quite uncomfortable that made suffering unavoidable. Li Tzu expanded his thinking: “The storms of the world should not make the waters of the internal lake rough. You can be arrested, but to take your freedom away you will have to allow it; you can be offended, but humiliation will only hit you with your consent; they can steal your money, but you will only lose your dignity if you surrender it; no conflict can rob you of your peace unless you permit it. A disease, old age or an accident can, at most, finish this existence, but never put an end to life. Happiness does not depend on the world, it is in your hands.” Some students started to arrive for their daily practice. They greeted Li Tzu and were told to go to the meditation room. I said good-bye to the Taoist master and was supposed to come back the next day, to begin my cycle of studies. I decided to go hiking in a mountain. For a reason I can’t explain, walking helps me think, when I am confused. Perhaps because it relieves tension. Little by little, the words of the Taoist master started to fit in. Lost luggage is something common nowadays and was not a lesson. However, inside my luggage I carried part of my habits. Things that, at first, were indispensable to my well-being. Not having my luggage would force me to break my routine beyond the trip in itself, as I believed at first. Routine, even though it may be boring at times, is overall pleasant because it includes habits we enjoy having. This is good because it makes us feel well. However, it may be bad when it becomes an addiction. When we think about addiction, we often think about drugs, whether legal or illegal, or other similar, obscure things. But it goes deeper. I realized that addictions are so surreptitious that, in some instances, we do not notice them. All that deludes us and makes us believe we cannot live without them is an addiction and, therefore, harmful because we cannot stop craving them. They become subtle prisons without bars. I understood that in my lost luggage I carried many of my addictions. And I noticed something worse. In my internal luggage, my conscience, there were also many of my addictions disguised as needs. Addictions are shadows that, as such, set us away from the light. The harshness of the gaze, the inflexibility of thoughts and automation of actions were some of such dangerous habits. One type of luggage spoke lots about the other. The latter reflected the former. What is indispensable to me? The answer was sophisticatedly simple: love and other virtues, because they are the instruments of freedom, peace, dignity, happiness and love itself, in eternal cycles of improvement. Where would I find them? Nowhere else but inside me. Therefore, I have all that I need. I was grateful that my luggage was lost. Because of that, I could now pack my luggage. I stopped to observe the view of the beautiful and flowered meadows we had from the top of the mountain, with infinite mountains behind. There, I realized all the strength and power I had in me. At that point, I became sure that, if I knew how to separate the wheat from the chaff and traded the weight of the world for the lightness of the soul, no flight would be impossible for me. Kindly translated by Carlos André Oighenstein.
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Conflict mitigation and management: Understanding the processes utilised by effective healthcare teams Authors: Marie O’Shea, University College Dublin, IE, Aoife DeBrun, University College Dublin, IE Introduction: Multidisciplinary approaches to patient care have become increasingly important. The delivery of safe care requires individuals from various professional backgrounds to work collaboratively. Previous research reports that poor collegiate relationships and unresolved conflict impact negatively on the safety culture. Yet, there is little guidance as to the processes that may be utilised by teams to manage conflict. Theory/Methods: Semi-structured interviews (n=25) were conducted with members of four healthcare teams identified to be working effectively through impartation of expert opinion. The transcripts were analysed using thematic analysis. The primary aim of the research was to understand the processes and characteristics of effective teams. This component of the research explored their conflict management processes. Results: The potential for negative conflict, arising from professional cultural differences, was mitigated by consciously placing the patient at the core of decision-making and by having knowledge of and mutual respect for each other’s roles.Open communication was regarded as key to the successful conflict management. Each team had a culture of shared leadership and strong interpersonal relationships that had been fostered by colocation and informal meetings and communication. These contributed to a culture of mutual support, collegiality and trust that facilitated open communication and mitigated the escalation of conflict. There was evidence of environment of psychological safety where members could challenge one another without the risk of causing offence. Decision-making was shared and facilitated through the use of dedicated, structured meetings where all members could contribute to decisions on patient care and team operations.Tensions arose from the personal traits of individuals (who were generally new to the team) who adopted inflexible attitudes, lacked understanding of the team’s processes and did not fit into the team’s culture. A formal induction onto the team was found to be effective in some instances. Discussion: The findings enable a better understanding of the characteristics and processes utilised by effective teams in conflict management. These can inform the development of conflict management interventions. Conclusion/Key Findings: Interpersonal conflict impacts adversely on a team’s ability to collaborate and deliver safe care. Effective teams anticipate the underlying antecedents of interpersonal conflict and adopt processes that serve to mitigate and manage potential issues. A culture that is supportive of open communication and the building of close personal relationships is crucial to a team’s ability to manage conflict. This culture flourishes where there is shared leadership. Lessons Learned: Teams may adopt processes that could reduce the propensity for negative conflict, such as defining a common goal around patient care, educating each other about their professional practices and introducing structures enabling all members to participate in shared decision-making. Limitations: The findings were drawn from semi-structured interviews with a cross section of four teams. In one of the teams only two members participated in the research. Suggestions for future research: Ethnographic research across the teams would reveal how effective these characteristics and processes are in managing conflict. The findings may also inform the design of interventions to reduce conflict in teams. Keywords: management, conflict, processes, multidisciplinary, collaboration, safety How to Cite: Zonneveld N, Miller R, Minkman M. Values and principles of person-centered integrated care: a systematic literature review (SIG meeting). International Journal of Integrated Care. 2017;17(5):A251 Published on 08 Aug 2019
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2023-09-27T12:21:16Z
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1. How long have you been working at Intellegens and what is your role? I joined Intellegens as HR and Talent Acquisition Manager, a new role, in July 2022 to help support the business through its next exciting chapter. Since joining I have reviewed and implemented a number of processes, benefits and systems to streamline the people focus, whilst helping the team settle into our nice new shiny office. 2. What is your favourite thing about working at Intellegens? The supportive and collaborative nature of the team. Having left my previous employer after 10 years it was important to find the right company, and I have not been disappointed in my decision to join Intellegens. The kindness everyone shows each other is remarkable. 3. What is your career/educational background? My initial career was in recruitment which helped me identify my want to help and support people. This led me into HR, and in 2021 I decided it was time to complete my CIPD HR qualification. I am one of the few people at Intellegens without a degree, but this has not held me back and I encourage everyone to continue focusing on their personal development and growth. 4. What is something that you think makes Intellegens stand out from other companies? Everyone’s dedication to company and client success. Regardless of roles, everyone strives to support, push forward, and enhance the business and its offerings to our clients. 5. What do you enjoy doing when you are not at work? Family and friends mean the world to me, it’s what keeps me focussed and grounded. My son started primary school in September 2023 and we are due our second child in January 2024, so depending on when this is read will depend on how much extra time is available for other out of work activities!
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Intellitech(Top E-Commerce Development Company, UAE) is a leading e-commerce and m-commerce application development company in Dubai, UAE, with industry specific developers and fully customizable shopping cart solutions. We also have expertise in customizing and developing Magento and open-cart solutions, matching with customizable requirements. We provide all advanced featuresfor launching an online store. Our ecommerce web development solutions include web hosting, shopping cart, account integration, store procedures, shipping integration, custom database, inventory tracking, special offer systems, and privilege cards and refer a friend program. With our B2C and B2B Ecommerce/ M-commerce Framework, we bring the clients, Resellers and the merchants at a single platform, which help both customers and the dealers. Customers have many advantages like they can shop from home, home delivery of goods, get customer reviews earlier and get complete information of the products.If you are the owner of an Ecommerce website you have benefits such as no need to rent or build a shop, automatic stock management, better transaction control, know trends of your customers and easy to manage everything in a single click.At Intellitech our ecommerce website and Magento web developers will help you to get these profits by providing you with an excellent web development service. The E-commerce or shopping cart solution developed by Intellitech ( E-Commerce Development Company in UAE) can be integrated with any third party applications or backend database. Our e-commerce web design and development services at Dubai, UAE cover all the bases necessary to sell your products and services online. We design Ecommerce systems for our clients with data security, usability and constancy in mind. Our services include everything required to create and process orders and keep customer information in such a way that fits the specific needs of our client's business. Magento ecommerce is latest trending Open Source platform with world class features to deliver the merchants with great controls and flexibility over their online store operations. As a best Magento website development company in Dubai, Intellitech provide you with professional Magento website design and development solutions. Our experienced web developers offer Magento shopping cart development and Magento ecommerce website development at an affordable and competitive price.
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2023-09-27T12:20:08Z
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The nights are long, the air is crisp, holiday lights are up: it's time to snuggle into your home with a mug of cocoa, a cookie, and some joyful holiday specials. We've collected some favorites that are available to stream by WTTW Passport members, from concerts to holiday episodes of our dramas and mysteries. And don't forget that we've also got a slate of holiday programming airing throughout the month, in case you'd rather let us choose for you what to watch! We've got two separate holiday specials, from a decade apart. First, he appears with Bing Crosby in a 1957 special directed by Sinatra himself. Then he and his family join Dean Martin and his family in 1967 for another evening of song and merriment. Ella Wishes You a Swinging Christmas with Vanessa Williams This concert might be from 2020, but it hearkens back to the era of Sinatra as well, being a tribute to the beloved 1960 album Ella Wishes You a Swinging Christmas by Ella Fitzgerald. This modern version features Vanessa Williams and other contemporary performers. Trans-Siberian Orchestra: Ghosts of Christmas Eve Another concert pulled from the archives is this 1999 rock opera by Trans-Siberian Orchestra featuring Jewel, Ossie Davis, and Michael Crawford. The Nutcracker and the Mouse King This is another musical special relaying a holiday story, this time with a traditional orchestra. Based on the original E.T.A. Hoffmann book that inspired the inescapable Tchaikovsky ballet, the concert features Alan Cumming narrating the story. The Mormon Tabernacle Choir The Mormon Tabernacle Choir's annual holiday concert also typically features an actor alongside the musical performances, and we have three recent versions, plus a twenty-year retrospective, for you to enjoy. Hugh Bonneville and Sutton Foster were the stars in 2018; Kristin Chenoweth took the lead in 2019; Kelli O'Hara and Richard Thomas appeared in the 2020 version filmed in 2019; and Brian Stokes Mitchell hosted a look back at numerous highlights. College and University Performances Some of the most popular annual holiday concerts come from colleges and universities, and we have several available to stream. There's one from St. Olaf in Minnesota, two from Belmont in Tennessee, and one from Wheaton outside Chicago. Straight No Chaser: The 25th Anniversary The a cappella group Straight No Chaser formed at a university (Indiana) before becoming nationally acclaimed. This anniversary celebration is holiday-themed. Pasquale Esposito: In the Spirit of Christmas Tenor Pasquale Esposito brings holiday cheer and visions of warmer weather in this special from Naples, which features both music and dance. Dramas and Mysteries Call the Midwife As a lead-up to the newest Call the Midwife holiday special airing on December 25 at 8:00 pm on WTTW, the four most recent holiday specials are available to stream for a limited time! Plus, we have recaps of them if you need to catch up. All Creatures Great and Small Whereas Call the Midwife seasons start with a holiday special, seasons of All Creatures Great and Small end with one. Given that a new season is coming in January, this is the perfect time to revisit the Yorkshire Dales! Again, we have recaps. Mary Berry must love the holidays, because she has granted us several specials. There's Country House at Christmas as well as two episodes of her Absolute Favourites. (There's also Mary Berry's Ultimate Christmas, not yet available for streaming, which airs on WTTW December 19 at 9:00 pm.) America's Test Kitchen There are a few holiday-centric episodes of America's Test Kitchen currently available to stream, focusing on eggs for the holidays (think eggnog), desserts and salads, and Jewish baking (for Hanukkah). There's also an hour-long special. New Scandinavian Cooking How She Rolls Carrie Morey prepares for the holidays in this special episode from the second season of How She Rolls. Lucy Worsley's 12 Days of Tudor Christmas Lucy Worsley discovers the beginnings of some modern Christmas traditions in the Tudor era in this special. Rick Steves' European Christmas Join Rick Steves as he celebrates the holidays across Europe, discovering long-standing traditions along the way, in this special. Merry Christmas Mr. Bean Join Mr. Bean in some festively hilarious mishaps in this special holiday episode. Welcome to My Winter Wonderland A Christmas tree farm, holiday tips and tricks, and more are on offer in this special Welcome to My Farm episode. The Joy of Painting with Bob Ross Bob Ross paints a little church snuggled amongst Christmas Eve snow and the evergreens.
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2023-09-27T12:59:56Z
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What if all of the gadgets to your existence should connect to the internet? Now not simply computers and smartphones, but the whole lot: clocks, audio system, lighting fixtures, doorbells, cameras, windows, window blinds, warm water heaters, home equipment, cooking utensils, you name it. And what if the one's devices may want to all talk, ship your data, and take your instructions? it's not technology fiction; it is the internet of things (IoT), and it's a key component of smart homes with home automation being an integral part. Domestic automation is exactly what it appears like automating the capacity to govern objects across the residence—from window sun shades to puppy feeders—with an easy push of a button (or a voice command). Some activities, like setting up a lamp to turn on and off at your whim, are simple and relatively cheaper. Others, like advanced surveillance cameras, can also require an extra severe investment of time and money. There are many smart domestic product categories so that you can manage the whole lot from lights and temperature to locks and security in your home. in addition, they manifest to make top-notch presents, whether you're shopping for the holidays or buying a housewarming present. Here is a rundown of the high-quality products we've examined for each room of the residence. Gadgets that help you run your house via the use of your voice rather than walking over to your wall mild, thermostat or hi-fi have become more and more common. They vary from protection cameras to smart lighting fixtures, connected audio system to watering gadgets in your flowers. Each of the gadgets here has its personal smartphone app so that you can control it remotely. Most paintings with any cellphone the use of their committed apps, however some, eve products as an example, handiest work with Apple devices. For the excellent results, it’s well worth having one of the structures that can manipulate the devices at once. Apple, Google and Amazon have a clever audio system that can listen to you across the room and may be controlled by using voice. Here is the list of top 10 hand picked must have smart gadgets- 1. Netgear Arlo Q Netgear Arlo Q is a Protection camera that guarantees clever domestic’s safety and the very best degree of human control. In different words, the capabilities of this representative of clever domestic devices include a capability to test your private home all of the time with the aid of storing the statistics at the cloud and the very best nice of the video. Moreover, the functionality of Arlo integrates the infrared lights for night time imaginative and prescient, a 2-way audio so that you can pay attention and communicate back by using a smartphone, basic cloud upkeep of the today's week’s recordings, and clever indicators on something that movements or makes a legitimate in the vision of this digital. With the relationship to Google assistant and amazon Alexa, net gear Arlo q can effortlessly grow to be a critical part of the community with other smart gadgets for the home. 2. Amazon Echo As a frequent leader in various ratings of the most treasured smart devices for home, amazon echo is a device that establishes the electricity of voice over all the primary activities. To make it work, the reference to Alexa assists this device in gambling the track, making calls, creating responsibilities and habitual lists, controlling the environment of a smart domestic and inquiring about thrilling data. in this context, the best of the replication is a top concern for the designers, and that they empowered this gadget with Dolby processing (beneficial in managing crisp vocals and dynamic basses) and 360° omnidirectional audio (to fill the entire place of the room with sounds). any other critical characteristic of amazon echo is its set of seven microphones, which makes it listen to the human voice from anywhere?—?and distinguish it from noises or historical past tune. As an end result, the capability of this smart domestic gadget may be confined via your creativeness handiest! 3. LG ThinQ Refrigerator ThinQ is an extraordinary potential three-door refrigerator with an eight-inch Wi-Fi liquid crystal display screen. It has an excellent design that offers garage alternatives, along with the flow and serves drawer. The contact display screen display interacts with your phone app. it serves the twin role of a controller and a statistics server. It allows you to hold an inventory of all perishable meals. In conjunction with that info, the refrigerator’s electricity-intake information is available. It has several apps, including meals manager and grocery app, which will let you make your buying list based totally on the inventory available. 4. Smart Faucet This tap saves up to 15,000 gallons per unit in line with the year. You could shop for water with this progressive era and assist preserve water assets. It additionally conserves electricity with its intelligent layout. Through keeping water and energy, you may leave at the back of a discounted carbon footprint. Smart tap is hygienic and contamination free, as there's no want to touch the tap valves. It’s far well-proper for youngsters, the elderly, and the disabled. It’s for a less expensive manner to preserve water and keep our environment. Vivint smartly provide you with cameras, a doorbell, out of doors cameras, a clever lock, amazon Alexa or Google home devices, a smart thermostat, a domestic tough pressure to preserve all your video sponsored up and the requisite sensors and alarms. They may be all accessed thru a Vivint clever hub. It is the type of like Google’s domestic hub, however without the AI. From there you can view all your cameras, manage your thermostat, take a look at the weather, and manipulate your device. 6. Robot Floor Mop This is some other one of those smart domestic merchandise that could rid you of unsightly cleaning chores. In case you without a doubt despise mopping the floors every other day, this robot mop will do it for you. All you want to do is pour little water into it and pick out the cleansing pad suitable on your flooring. This smart mop can cover as much as one hundred square feet in only an hour and make your floors sparkle with new intensity. 7. Robotic Kitchen Chef This is one of the best specimens domestic automation generation has to provide. This cooking robot has found out from the best by way of gazing and now mimicking the actions of pinnacle chefs inside the industry. When you have no electricity to prepare dinner or want to come again home to an already prepared meal, this robotic chef will do the work for you. You could pick numerous recipes from an app library and feature the meals made for you. Ideal 8. Philips Hue Philips became the first agency to create clever lights and remains at the leading edge of the era. A starter package gives you a bridge unit that connects for your router and 3 bulbs which might be white most effective or have white and thousands and thousands of colours. You may set schedules or turn the lights up gently in the morning to wake up to a dawn effect, as an example. One component that you might want to do as soon as making a decision to make your sweet home a smart domestic is switching out the light bulbs – something less complicated stated than done considering what number of one-of-a-kind options out there. However, we assume the best clever light bulbs are Philips hue variety of smart bulbs. If you opt for Philips Hue bulbs, you may want to get the Philips Bridge, that's kind of like a hub on your lighting fixtures. The gain, but, is reliability, and the truth that the system is well matched with a variety of different requirements and home manage structures along with Apple home kit, nest and Samsung SmartThings. If you pass on vacation and overlook to turn lighting fixtures off – or on – you may manage this out of your telephone. if you have an amazon echo plus, a like-minded hub is built in, so that you don’t want the bridge unit. 9. Nokia Body Cardio bathroom scales Connected lavatory scales, eh? That’s proper, and they’re splendid. Every time you weigh yourself, the scales let you know your weight, body water content, fat content and greater. no longer to say the climate forecast for the day and your coronary heart price. Then, it saves every dimension to the Nokia fitness app in your telephone or online so you can monitor your weight advantage or loss over a duration, spotting developments in a manner that’s difficult in any other case. A training programme can ship you gentle encouragement through email that will help you attain your favoured weight. You could study your weight in kilos, lbs. or stones and lbs. the scales are clever enough to realize who’s standing on them just from the burden, so numerous participants of a circle of relatives can use them. They a chargeable battery and come in black or white finishes. Knocki turns any surface it is attached to into a hint-based totally interface to govern your own home generation. You can assign unique tapping and knocking patterns to exclusive movements, as an instance, faucets switch on the TV, three knocks locate your phone. You could even attach it to your door while you’re making plans on spending some time inside the outside. This way if someone involves the front door and knocks, you’ll get a notification to your smartphone. So nowadays you can make your smart and connected. There are several smart gadgets available and some are being raised. Soon everyone around will have all the ease of technological advancement and home automation. Technology is making our lives easy as the same place fitness and health is being the concern. No doubt these gadgets will do all the repetitive and day to day works but one should also focus on some physical workouts to stay healthy and fit. Have happy automation!
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When it comes down to the Wi-Fi routers, it is essential to choose the right ones because it directly influences the data-transfer speed, device management, and signal quality. In simpler words, it is essential for improving the performance and connectivity of the internet connection. Having said that, if you are trying to purchase a new router, we have the Netgear AX4300 vs. AX5700 comparison laid out in this article to assist you. Netgear AX4300 vs AX5700 This Wi-Fi router is designed to offer faster downloading, streaming, and connectivity speed of up to 4.3Gbps without causing any hindrances in the connection. The router is integrated with the 1.5GHz processor with a triple-core configuration that makes sure the router doesn’t overheat (overheated router can slow down the internet connection) and keeps performing well. In addition, it has an offloaded CPU which positively influences the network performance. Netgear AX4300 router is designed with advanced and high-end Armor technology, which offers high-end cyber threat protection. With its ability to support ultra-fast internet speed, it can be used for streaming UHD and 4K streaming along with video conferencing and gaming. In addition, it can be used to support the smart home devices in addition to streaming videos simultaneously, given the 3.5x higher performance standards. When it comes down to channel support, it has 160MHz support, which increases the internet speed by two folds to offer gigabit-speed for compatible laptops as well as smartphones. In addition, the Wi-Fi router has OFDMA, which increases the upload and download speed as it can transmit internet signals to multiple devices. Netgear AX4300 has a dual-band wireless configuration that offers a dedicated and reliable wireless network without causing internet congestion. Netgear AX4300 has four Ethernet LAN ports that allow the users to connect wired devices to ensure uninterrupted internet connection and high-speed file transfer. There are various DFS channels that reduce network interference. On top of everything, it has four external antennas that offer a better internet range for small as well as medium homes. It works with the Nighthawk app that allows the users to set up the router and change the settings. Even more, it has a USB 3.0 port that promises ten times better internet connection. Last but not least, its Wi-Fi 6 technology, supports connection with all wireless devices. Netgear AX5700 Wi-Fi Router Netgear AX5700 router is known as the home router, and it’s one-of-its-kind with multi-gig internet connectivity support. It promises the fastest wireless internet speed, which supports UHD, 4K, and 8K streaming with simultaneous video conferencing and gaming. The best thing about this Wi-Fi router is that it increases the connectivity performance for multiple smart home devices, even during the rush hour of the internet. This router can support internet speed up to 5.7Gbps, which promises five-fold better internet performance and wireless speed. It has a 1.8GHz processor with a quad-core configuration that streamlines the streaming, even for advanced resolution. Netgear AX5700 comes with 160MHz channel support, which increases the internet speed by two folds to offer gigabit internet speed for compatible desktops, laptops, and mobile devices. On top of everything, the MU-MIMO feature in the Wi-Fi router allows faster data transfer while streaming content on multiple devices. It has an OFDMA that promises high download speed and upload speed. In addition, it is integrated with the link aggregation support that maximizes the internet speed. It has four hidden antennas that help extend the internet range for bigger homes. The best thing about this router is that it’s easy to install and has convenient management with the Nighthawk app (the app can be used for setting up the router as well). There are two USB 3.0 ports that offer a ten-fold faster internet connection as compared to Netgear AX4300, which only has one port. It is integrated with ReadyCLOUD USB access, which helps achieve secure cloud access for USB-based storage. Not to forget, it comes with the ReadySHARE Vault that promises automated backup for PCs. If you are concerned about security, it has the Armor feature, which protects the internet network from hacking attempts, malware, identity theft, and stolen passwords. To summarize, both of these routers are pretty great, but Netgear AX5700 is a better choice for bigger homes.
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TOP 10 Frequently Asked Questions1. What states do you ship to? 2. What happens when I select shipping to a Walgreens? 3. Why was my card declined? What does "Merchant Override Decline" mean? 4. What size are the bottles? 5. How quickly are items shipped out? 6. Do you sell bottles that are in perfect condition for my collection? 7. What happens if I'm not available to sign for the package? 8. Do you accept international orders? 9. Do items come with a box/tube? 10. How do I find a product available in my state if Internet Wines doesn't carry it or can't ship to my state? Q: What states do you ship to? A: Orders for wine, spirits, or beer may be shipped only where not prohibited by law. Title of ownership for all alcoholic items transfers to buyer at time of purchase. Buyer assumes all responsibility for alcoholic shipments and is assumed to be familiar with any and all applicable laws regarding shipment of alcohol to the destination provided. We currently ship to AK, CA, DC, FL, IL*, LA, MO, NE, NH, NM, WY. (*Available in IL only if we can get the product at our IL store.) Q: What happens when I select shipping to a Walgreens? A: Orders shipping to a Walgreens will be sent to the participating Walgreens/FedEx location nearest to your shipping address, unless another preferred Walgreens address is provided by you. Upon shipment of your items, a tracking number will be emailed to you. Follow the tracking information to see when your package is available for pickup at the Walgreens. The selected Walgreens address should be provided on the tracking information. If it is not, please call us and we will be able to provide the address for you. If the package is not picked up within 5 business days from Walgreens, it will be sent back to us and the shipping charge will not be refunded to you. Q: Why was my card declined? What does "Merchant Override Decline" mean? A: Your card is being declined for one of a few reasons: 1. The billing address entered online must be entered exactly as it is registered to the card. Check your billing statement or call your bank to see how the address appears exactly. (Example: Road must not be abbreviated as Rd.) 2. Foreign billing addresses and foreign credit cards are not accepted by our system. 3. Credit cards that have fraud protection will be declined unless you tell your bank or credit card company to authorize the merchant “Internet Wines & Spirits”. 4. The credit limit may be reached on your card or your debit card has a zero balance. **PLEASE NOTE** Every time your card is declined on our website, you will see an authorization hold on your card. This is NOT a charge, but merely a hold to verify the card. This hold will fall off within a business day or two. If the hold doesn't fall off within a few days, contact your bank or credit card company. Q: What size are the bottles? A: All bottles on the site are 750ml unless otherwise noted in the title or description. Q: How quickly are items shipped out? A: Barring complications, your order will be shipped out within 2-3 business days after being processed. (This does not include weekends!) Q: Do you sell bottles that are in perfect condition for my collection? A: We sell items for consumption, not collections. Labels may be slightly scuffed, and original packaging may not be included. InternetWines.com sells items exclusively for use by the recipient of the order. These items are not intended for resale, and the sale of alcohol without a license is a crime in the United States. No alcoholic item should therefore be considered to have collectible value. We will always do everything we can to ensure your items arrive in the finest possible condition, but we are not responsible for any dings, dents, defects, scratches, scrapes, or marks that might be seen to diminish an item's perceived collectible value. Q: What happens if I'm not available to sign for the package? A: FedEx will attempt delivery three times. If you are not home, the business is closed, or someone over 21 is not available to sign, the package will be sent back to us. You can choose to have the package resent, but we will need to charge shipping once again. If you want a refund, we will only be able to refund the cost of the product, not the shipping. Alternatively, if you think you will not be home to sign for the package, you can choose shipment to a Walgreens/FedEx location. Q: Do you accept international orders? A: No. We do not ship internationally (outside of the United States). In addition, we cannot accept foreign credit cards with foreign billing addresses. Q: Do items come with a box/tube? A: As a rule of thumb for our website, anything pictured with a box/tube will ship with the box/tube. Some heavier boxes cost more for shipping, so you will notice the shipping charge increases in the cart. If you would like to save on shipping costs or would prefer not to have the extra box/tube, put in your notes at checkout that you'd like to skip the box/tube. We will adjust your shipping cost (if necessary) and refund the difference after the order has been placed. (Some items do not have an increased shipping cost due to the packaging.) Q: How do I find a product available in my state if Internet Wines doesn't carry it or can't ship to my state? A: Unfortunately, we do not have any information regarding availability of products in other states. We do, however, recommend using the website www.WineSearcher.com. MORE FREQUENTLY ASKED QUESTIONS Q: What is your cutoff time for ordering? A: We have an official cutoff time of 9:00am CST for same day processing. Orders can take up to 2-3 business days to process and will be shipped out according to the shipping type you purchased. (Orders are processed Monday through Friday.) Q: Why is there no order button for the product I want to purchase? A: If there is a SOLD OUT button, then we are out of stock on that item at this time. In most cases, the product will be restocked. Email us or call us and we will let you know the status of the item in question. Q: Do I need to be 21 to order? A: YES. You must be 21 or over to place an order with us. A signature will be required from an individual 21 years or older upon delivery. Q: What if I order something that is out of stock? A: If we expect to be out of an item for more than 3 days, we will contact you for replacement or substitution. Q: How safe is sending my personal information and credit card number over the web? A: It is very safe. The information you send is secured and encrypted using SSL technology. This makes it very difficult for anyone to intercept and interpret your information. It is certainly safer than giving someone your information over the phone. Q: What does Internet Wines do with my personal information? A: We do not share/sell any personal info gathered by this site with anyone. Q: How often do you update your prices? A: We update our prices daily. Q: I ordered gift wrap, but the item was not wrapped before shipping. Why is this? A: We sincerely apologize for the inconvenience, but unfortunately a few odd-shaped items cannot be gift wrapped. Q: Why does the phone number listed on the web dial a place called "Randall's"? A: "Internet Wines and Spirits" and "Randall's Wines & Spirits" are one and the same. The number you have dialed is our base of operations in St. Louis, Missouri. Randall's is a family-owned wine and spirits store, operating 5 locations in the Metro St. Louis, Missouri area. If you ever find your way to the area, be sure to drop by the store. Q: I have a problem with my order, how do I fix it? A: We are available Monday-Friday 10am-6pm CST via phone at 1-877-624-1982 or you can contact us via email. Please have your order number ready. (It can be found in your confirmation email. It is a 6-digit number after the IWS.) Q: Do I pay sales tax? A: We are only required to collect sales tax for items which are either picked up at the store or shipped to residents of Illinois, New Hampshire, or Missouri. Q: Are these prices/items available at your St. Louis or Fairview Heights, IL stores? A: Prices and availability reflected on our web site are in no way representative of our retail stores in St. Louis, MO or Fairview Heights, IL. For store pricing and availability, please call 314-865-0199. Q: Can I include a gift message or special instructions with my order? A: You can add a gift message or special instructions to your order on the checkout page. Prices are not included on the packing slip. Q: The item I purchased arrived damaged. How do I return it? A: Simply return the damaged product to its original shipping box (including original packaging materials), and call us toll-free at 1-877-624-1982. If you prefer, you may also e-mail us. We will then send FedEx to inspect / collect the damaged merchandise. Once FedEx has collected the package, we will send a replacement or credit your account accordingly. If your package contained multiple items, please return only the damaged portion of your order. Internet Wines.com sells items exclusively for use by the recipient of the order. These items are not intended for resale, and the sale of alcohol without a license is a crime in the United States. No alcoholic item should therefore be considered to have collectible value. We will accept returns or issue refunds for items damaged in a way that substantially impairs their use. We will always do everything we can to ensure your items arrive in the finest possible condition, but we are not responsible for any dings, dents, defects, scratches, scrapes, or marks that might be seen to diminish an item's perceived collectible value. Q: If I purchased an item at regular price and it goes on sale shortly thereafter, can I get a refund for the price difference? A: If the item or items you purchased are now lower in cost AND it has been no more than 7 days since your purchase date, we will give you a refund for the price difference. Q: How long do I have to return an item? A: You have 30 days from the date you received your package to return your item(s). Q: Do I have to pay to ship my item back to you? A: If the item is damaged, we will send a FedEx return tag to you via email. Place the damaged item in the original packaging and send it back to us. Once we receive the item, we will send a new one to you. If the item you receive isn't damaged, but merely you changed your mind and want to return it for a refund, you will be charged a return shipping fee to send it back to us. Once we receive the item, we'll refund your card for the original item that was returned, but we'll also charge you for the return shipping fee. Q: Why did I get charged $15 for a FedEx Address Correction? A: FedEx makes every attempt to deliver your package to the address you've given us on your order. However, in some cases, these addresses are undeliverable due to an invalid zip code, missing suite number, etc. In order to deliver these undeliverable packages, FedEx will determine the correct address, complete delivery, then notify us that they had to take extra steps to deliver the package. You will receive notification from us stating that we are charging you for this FedEx Address Correction fee. Q: What does SHIP PARTIAL mean exactly? A: At checkout, if you select ship partial, we will ship whichever items in your order that are currently in stock at our warehouse. We will adjust your order total and shipping cost to get the items out quickly. We will not, however, ship the other items that were left off the order. You will have to re-order those items in a completely new order. Q: What types of payment do you accept? A: We only accept Visa, Mastercard, American Express & Discover cards. Q: My order shipping to Illinois/Missouri was cancelled. I thought you shipped to Illinois/Missouri? A: We have 2 warehouse locations: one in Missouri, one in Illinois. If the shipping address for your order is Illinois and the product is only available at our Missouri store, we cannot transfer it to the Illinois store to fulfill the order. (And vice versa for Missouri orders.) Due to state liquor laws, we cannot transfer items between our two stores. If you have an address that is in another state we can legally ship to, we can gladly fulfill the order. Our ordering system cannot decipher between MO/IL orders, therefore we go through each order individually. Q: I don't like FedEx. Can't you just use UPS to ship my order? A: We have an exclusive contract with FedEx, therefore they are the only shipping company we can use to ship our orders. We also cannot use a shipping label provided by a customer. All orders must be shipped using our shipping labels and our FedEx shipping account. Q: Is it safe to ship wine & spirits in hot/cold weather? A: During extreme weather in the Summer and Winter months, we recommend delaying shipments to ensure the safety of your product(s). We do not like to ship wine if the weather is above 85 degrees or below 32 degrees. We ship spirits in the summer, but delay shipment in the winter for items under 50 proof, since the liquid can freeze. We will hold your order in our temperature controlled warehouse until weather permits. Please let us know at checkout if you require us to hold your order due to weather, otherwise we will decide what's best for the product and keep you informed about your order via email. Q: Is there a list of Walgreens locations I can have my order sent? A: To see a list of Walgreens locations that offer FedEx package pickup, visit Walgreens.com and use the Store Locator. Enter your shipping address to see which locations are nearest to you. If a location says "Pickup & Delivery Available", then you can use that location for FedEx package pickup. In addition, if you would like a certain Walgreens location for your order, please put the address in the order notes at checkout.
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Professional Services Invoice Template A professional services invoice is for an individual that performs a trade that, most commonly, needs a license to do their work. If the service provider requires a license, the client is usually able to perform a lookup and verify the person holds a license for a specific jurisdiction. A professional service is typically hired on a per hour ($/hr) basis for consulting and additional labor. Examples: Lawyer, doctor, dentist, accountant, architect, hairstylist, etc.Make a Free Invoice Now By Type (12) What are Professional Services? There are two (2) definitions of professional services: 1.) Licensed Professionals – Any trade where the individual is required to receive a certification or license by attending trade schools, getting trained, and passing a standardized test. 2.) Ethical Standards – Any trade where the individual has a high level of expertise in the specific industry and carries themselves in a polite, respectful manner in front of others. This can also be synonymous with a person that holds a certification or designation from an organization within their industry.
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Innoviz Technologies to Present at Upcoming Investor Conferences TEL AVIV, Israel, June 12, 2023 /PRNewswire/ -- Innoviz Technologies Ltd. (Nasdaq: INVZ) (the "Company" or "Innoviz"), a leading Tier-1 supplier of high performance, automotive-grade LiDAR sensors and perception software, today announced its in-person participation in the following upcoming investor conferences: - Deutsche Bank's Global Auto Industry Conference - Senior management will attend the conference at the Deutsche Bank Center in New York, meet with investors in-person, and participate in a fireside chat moderated by Deutsche Bank, on June 14, 2023 at 1:35pm - 2:10pm ET. Registration for the live webcast of the event is available here. - Cantor Fitzgerald Technology Conference - Senior management will attend the conference in New York and hold individual meetings with investors. Management will also hold a formal panel presentation titled 'LIDAR, Radar & the Adoption of Autonomous Vehicles' on June 15, 2023 at 3:50pm - 4:30pm ET. Live webcasting is not being offered at this conference. About Innoviz Technologies Innoviz is a global leader in LiDAR technology, working towards a future with safe autonomous vehicles on the world's roads. Innoviz's LiDAR and perception software "see" better than a human driver and reduce the possibility of error, meeting the automotive industry's strictest expectations for performance and safety. Operating across the U.S., Europe, and Asia, Innoviz has been selected by internationally recognized premium car brands for use in consumer vehicles as well as by other commercial and industrial leaders for a wide range of use cases. For more information, visit innoviz-tech.com. Investor Contact (US) Investor Contact (Israel) Rob Moffatt Maya Lustig VP, Corporate Development & IR Director, Investor Relations Innoviz Technologies Innoviz Technologies +1 (203) 665-8644 +972 54 677 8100 SOURCE Innoviz Technologies Released June 12, 2023
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Background: The assessment of potential benefits and harms of a medical procedure is essential for both physicians and patients to make an informed choice among treatment options. There is a paucity of studies on the role of creatine kinase-MB (CKMB) in the prediction of patient outcome after elective percutaneous intervention Objectives: The current study aimed to assess the association of CKMB level with demographic characteristics and major adverse cardiac events (MACES) after percutaneous coronary intervention (PCI) with drug-eluting stent implantation. Methods: The study was conducted based on the data concerning the consecutive patients hospitalized for PCI and followed for 12 months. We examined the association between CKMB levels at 12 h post-PCI in patients with drug-eluting stent implantation and demographic characteristics. MACEs were defined as death, myocardial infarction, the need for re-revascularization in the first 48 h after the procedure and during a 1-year follow-up in 2898 patients who underwent PCI in Tehran Heart Center within 2015-2016. Results: In multivariate logistic regression, after adjustment for differences, no relationship was observed between CKMB level at 12 h post-PCI and 12-month MACEs; nonetheless, in-hospital MACEs were higher in patients who had CKMB> 3 times the upper limit of normal. Furthermore, thrombus, angulated segment, and coronary perforation during the procedure were more prevalent in patients with higher CKMB levels. Conclusion: The obtained results demonstrated that in patients with elective drug-eluting stent implantation, the moderate elevation of post-procedural CKMB>3 times was associated with in-hospital MACEs. Moreover, no association was found between 1-year adverse events and >3 times the elevation of CKMB. Sarraf-Zadegan N, Sayed-Tabatabaei F, Bashardoost N, Maleki A, Totonchi M, Habibi H, et al. The prevalence of coronary artery disease in an urban population in Isfahan, Iran. Acta Cardiol. 1999;54(5):257-63. [PubMed: 10596304]. Sellgren A, Nilsson F, Jeppsson A. The relationship between ASAT, CKMB, troponin-T and mortality after cardiac surgery. Scand Cardiovasc J. 2007;41(6):386-90. doi: 10.1080/ 14017430701400104. [PubMed: 17852782]. Sá MP, Ferraz PE, Escobar RR, Martins WN, Lustosa PC, Nunes Ede O, et al. Off-pump versus on-pump coronary artery bypass surgery: meta-analysis and meta-regression of 13,524 patients from randomized trials. Rev Braz J Cri Cardiovasc. 2012; 27(4):631-41. doi: 10.5935/1678-9741.20120106. [PubMed: 23515737]. Abdelmeguid AE, Topol EJ, Whitlow PL, Sapp SK, Ellis SG. Significance of mild transient release of creatine kinase–MB fraction after percutaneous coronary interventions. Circulation. 1996;94(7):1528-36. doi: 10.1161/01.cir.94.7.1528. [PubMed: 8840840]. Kushner FG, Hand M, Smith SC, King SB 3rd, Anderson JL, Antman EM, et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Catheter Cardiovasc Interv. 2009;54(23):2205-41. doi: 10.1002/ccd.22351. [PubMed: 19924773]. Alhadi HA, Fox KA. Validity of cardiac markers as diagnostic and prognostic indicators of complications in patients undergoing percutaneous coronary intervention. Sultan Qaboos Univ Med J. 2010;10(1):31-40. [PubMed: 21509079]. Kong TQ, Davidson CJ, Meyers SN, Tauke JT, Parker MA, Bonow RO. Prognostic implication of creatine kinase elevation following elective coronary artery interventions. JAMA. 1997;277(6):461-6. [PubMed: 9020269]. Ioannidis JP, Karvouni E, Katritsis DG. Mortality risk conferred by small elevations of creatine kinase-MB isoenzyme after percutaneous coronary intervention. J Am Coll Cardiol. 2003;42(8):1406-11. doi: 10.1016/s0735-1097(03)01044-1. [PubMed: 14563583]. Kini AS, Lee P, Marmur JD, Agarwal A, Duffy ME, Kim MC, et al. Correlation of postpercutaneous coronary intervention creatine kinase-MB and troponin I elevation in predicting mid-term mortality. Am J Cardiol. 2004;93(1):18-23. doi: 10.1016/j.amjcard.2003.09.006. [PubMed: 14697460]. Ellis SG, Chew D, Chan A, Whitlow PL, Schneider JP, Topol EJ. Death following creatine kinase-MB elevation after coronary intervention: identification of an early risk period: importance of creatine kinase-MB level, completeness of revascularization, ventricular function, and probable benefit of statin therapy. Circulation. 2002;106(10):1205-10. doi: 10.1161/01.cir.00000 28146.71416.2e. [PubMed: 12208794]. Stone GW, Mehran R, Dangas G, Lansky AJ, Kornowski R, Leon MB. Differential impact on survival of electrocardiographic Q-wave versus enzymatic myocardial infarction after percutaneous intervention: a device-specific analysis of 7147 patients. Circulation. 2001;104(6):642-7. doi: 10.1161/ hc3101.093902. [PubMed: 11489768]. Abdelmeguid AE, Topol EJ, Whitlow PL, Sapp SK, Ellis SG. Significance of mild transient release of creatine kinase-MB fraction after percutaneous coronary interventions. Circulation. 1996;94(7):1528-36. doi: 10.1161/01.cir.94.7.1528. [PubMed: 8840840]. Kugelmass AD, Cohen DJ, Moscucci M, Piana RN, Senerchia C, Kuntz RE, et al. Elevation of the creatine kinase myocardial isoform following otherwise successful directional coronary atherectomy and stenting. Am J Cardiol. 1994;74(8):748-54. doi: 10.1016/0002-9149(94)90427-8. [PubMed: 7942542].
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Abstract A platelet (PLT) function modification has been reported in normal pregnancies compared with the nonpregnant condition and it has been hypothesized to play a central role in the pathogenesis of pregnancy-induced hypertension (PIH). The aims of the present study were (i) to evaluate the lipid composition, fluidity at different depths, transport functions, and ultrastructural features of the PLT membrane in PIH and (ii) to ascertain whether similar modifications may be determined by the state of pregnancy in comparison with the nonpregnant condition. The platelets of healthy pregnant women (HPW) showed: (i) an increase in Ca2+ ATPase activity, (ii) a decreased fluidity of the deeper site of the membrane, (iii) a reduced cholesterol concentration, with an increased ratio between unsaturated and saturated fatty acids; (iv) a decreased intramembranous particles (IMP) distribution factor (DF) of the plasma membrane E face in comparison with healthy nonpregnant women. When comparing women affected by PIH with HPW, we observed (i) reduced Na+/K+ ATPase activity and enhanced Ca2+ ATPase activity and intraplatelet calcium concentrations, (ii) an increased membrane fluidity, (iii) an increased cholesterol concentration and ratio between unsaturated and saturated fatty acids, (iv) a reduction of the IMP number and the DF. Pregnancy produces a deep modification of the platelet plasma membrane, and PIH produces a more pronounced alteration of the maternal platelets, which can be responsible for the observed modifications in placental blood flow and in the fetomaternal exchange. Biochemical-morphological modifications of platelet membranes during pregnancy-induced hypertension / Rabini, Ra; Salvolini, Eleonora; Staffolani, R; Pugnaloni, Armanda; Simonelli, L; Biagini, G; Cester, N; Garzetti, Gg; Mazzanti, Laura. - In: EXPERIMENTAL AND MOLECULAR PATHOLOGY. - ISSN 0014-4800. - 63:3(1995), pp. 175-185. [10.1006/exmp.1995.1041]
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As the pandemic rages on, gyms have mostly transitioned to contain on the web applications, quite a few with are living exercise routine courses you can sign up for on Zoom. I lately sampled a handful of, and while I chosen them to the YouTube routines I’d been executing before, I’m having difficulties to keep inspired. Extra typically than not I notify myself I’m heading to tune into a class and then really do not indicator up, opting for a nap or a snack as a substitute. Meanwhile, my stomach has turned to mush and my despair and nervousness are on fire. How can I get the most out of these Zoom conditioning classes all over again and experience far more fully commited to property workout? I turned to previous fitness center rats and house exercise champions to discover out. I also talked to therapists to find out why performing out in a team — albeit virtually — can advantage our psychological overall health. This is what they proposed: 1. Designate a set room for exercise routines “I know that room could possibly be at a premium, in particular when your family members is really considerably executing all the things from dwelling these times, but consider to make a house that is selected for the training,” explained Teralyn Sell, Ph.D., a accredited clinical counselor in Wisconsin. “That way you are placing more of an intention to truly do the work out.” Fabiana Meléndez, a PR strategist in Austin, Texas, located that all you actually need to have is a corner of your apartment — just fold up your mat when performed and leave it in the very same spot. “[This] assisted my mind compartmentalize and understand that there was an entire area for doing the job out,” Meléndez told Nowadays. 2. Build exercise temper lights Meléndez’s recommendation to change the lights to align with your workout struck me as nothing at all limited of genius. Why hadn’t I assumed of this? Of study course I can’t loosen up in a savasana pose with fluorescent lights beaming down on my eyes. If performing out in the night, a light up Bluetooth speaker could support make the temper additional tranquil, or even just turning off the overhead and flicking on a flooring or desk lamp. 3. Don’t just be part of any old Zoom class “When picking out your on the net exercise sessions do some investigate in advance of,” explained Alexandra Weissner, co-founder at Brunch Jogging in Colorado. Weissner encourages men and women to get a sense for the health club and the lessons it features by looking at how the local community engages on social media. “Are their personal Fb teams where by everybody chats? Are they hosting Instagram Life wherever you can inquire inquiries? Do they send you customized texts to check with how you’re emotion — and examining in?” Having to pay focus to these things will enable give you a feeling of what the course working experience might be like. 4. Invite a pal Gym memberships normally come with a move or two to bring a friend. You can embody this spirit of sharing on Zoom by inviting close friends to sign up for, much too. Getting another person you know in the Zoom home with you can assist make “accountability and enthusiasm,” mentioned Weissner. 5. Use the Zoom chat attribute “I try to use the chat attribute at the beginning and finish of the exercise routine to shout out to the instructor to permit them know I received a thing out of the course,” explained Nate Atkins, an investment decision banker in Maryland. “I also have a group chat with close friends that I have made from [my] exercise club and we’ll text the day just before about what courses to attend to consider and coordinate our workouts in spite of getting on the web.” 6. Use a Tv set as a substitute of a notebook “Instead of working with your computer display screen, decide for a television (or observe) that could possibly have a larger screen,” suggested Offer. “This will give you more of an illusion that you are essentially with the other men and women. Don’t pressure your eyes and overall body by seeking to do the class on your telephone.” 7. Make your own playlist “Chances are the instructor is heading to mute you so acquiring the right playlist even though you are in downward canine or doing Zumba can also be a good motivator,” reported Meléndez. “This is your just one hour to play what you want as loud as you want whilst allowing go of any anxiety. I normally have the laptop audio synced to a Bluetooth speaker so I can listen to the teacher in excess of the new music, and then enjoy music off my mobile phone or Alexa.”’ 8. Adhere to a plan “Find a time in the day that is conducive to doing the job out. It may be the time that you are commonly mindlessly scrolling by social media,” mentioned Market, who pointed out that you may be scrolling on the web in an effort and hard work to wind down immediately after a busy day, but a gentle yoga class will do the trick in a extra healthful way. “Alternatively if you get the [aftermoon] slumps, hop in to a cardio exercise to obtain some a great deal essential vitality by means of adrenaline and dopamine bursts.” What ever time slots you decide on, make it a practice. “The extra persistently satisfying we are, the much more most likely we are likely to don’t forget to do that again and once more,” stated Market. 9. Address on your own afterward “One way I keep inspired for an on the internet physical exercise session is by attaching the exercise to an exterior reward that I deal with myself to write-up-training,” reported Glen Wilde, CEO of Food plan to Achievements, a diet program coaching company dependent in California. “For me, that reward is an hour of totally free time for me to spend as I want. My leisure time begins instantly following the exercise, which helps make it all the extra gratifying.” Wilde has also identified a dazzling side: because he no for a longer period has to commute from the gymnasium to home, he can ride out his “runner’s high” in complete relaxation, whereas ahead of “the runner’s high has mostly dissipated by the time I acquired dwelling.” 10. Try to remember that this is a terrific way to continue to be social No issue how you spin it, a t eam class on Zoom does not have the identical magic of a team course in “real life” — but the social factor is continue to there, and which is important for receiving through this tense, terrifying time. “Online group physical fitness fosters link to other men and women,” said Naomi Torres-Mackie, Ph.D., a psychologist in New York Metropolis. “This feeling of belonging is the most vital ingredient for battling the quarantine and social distancing blues. Despite the fact that almost nothing can thoroughly take the place of reside in-man or woman team conditioning where by you share a space with other folks who are executing a thing hard suitable alongside you, the on line physical fitness movement delivers so many of the positive aspects without the need of the current threats.”
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The Fionn mac Cumhaill Series is a series of Irish mythological and adventure novels based around some of the early events outlined in Macgnímartha Finn (The Boyhood Deeds of Fionn). An exciting contemporary version of a narrative that’s almost a thousand years old, the Fionn mac Cumhaill Series recounts the adventures of the young Fionn (originally known as Demne) and the people who protected him during his upbringing at Ráth Bládhma: his aunt Bodhmhall, the woman warrior Liath Luachra, Fiacail mac Codhna and Muirne Muncháem. Although the series is a work of fiction, it is far more historically accurate than any other existing version of the tales and aligns completely with the original 12th century manuscript on which it is based. This series introduces rare ancient Irish cultural concepts and insights into the tribal systems that have been omitted from all previously published works. There are six novels planned: Book 1: FIONN: Defence of Ráth Bladhma (available in ebook and also in paperback) Book 2: FIONN: Traitor of Dún Baoiscne (available in ebook form and in paperback) Book 3: FIONN: The Adversary (available in ebook form and in paperback) Book 4: FIONN: Stranger at Mullán Bán (available in ebook form and in paperback) Book 5: FIONN: The Betrayal (anticipated release Dec 2023) Book 6: Untitled This unique Irish adventure series allows some of the stranger and lesser-known elements from the ancient social structures to be introduced in an accessible manner. Although the books are painstakingly researched and as authentic as possible, they’re also pure, unadulterated action and adventure. The first book in the series (FIONN: The Defence of Ráth Bládhma) came 4th (out of 300 entrants) in the highly competitive SPFBO 2016 fantasy competition and we’re pleased to say our other books have been just as popular.
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In the last question the catechism instructed us as to the definition of “true faith.” In the following questions the Catechism sets the table for a detailed examination of our undoubted Catholic Christian Faith. Because these next few questions are basically table setting questions for the following questions we will be able to examine more than one question today. As the catechizers have established what true faith is, they next turn to the issue of what it is necessary for a Christian to believe. They have given us a definition of faith and now they turn to the truths upon which our faith must be anchored. A couple of things to note briefly here before we turn to question 22. First, as we have mentioned before, this emphasis that we find in the catechism on the issue of the content of our faith reminds us again that Christianity is the life of the mind. Question 22 asks, “What is then necessary for a christian to believe,” not, “What is necessary for a Christian to feel,” or, “What is necessary for a Christian to experience.” As we have said feelings and experience have their place in the Christian life but it is what we believe — what we embrace as truth — that is the essence of the Christian faith. Second, we should note that “Faith” is an inescapable category. What I mean by this is that all men live by faith in something or someone. It is not as if only Christians have faith, or only religious people have faith. Every living breathing person you meet has some kind of faith. The humanists have faith. They have faith that man, by the use of putatively autonomous right reason, can arrive at true truth quite apart from any religious considerations. (Of course thinking that one can arrive at truth apart from any religious consideration is a religious faith consideration.) The Materialists have faith that everything happened by time plus chance plus circumstance. Since they were not there, there is no way they can know that their materialism is true. Besides, for the materialists, can there even be discussion about “true,” since “true,” for the materialist, is only the firing of random chemicals in our purely material brains? If the brain secretes thought the way the liver secretes bile can the materialist really speak about “truth?” When it comes to faith the difference for the Christian and the pagan is that the pagan’s faith reduces to “faith in faith,” while the Christian’s faith is faith anchored in divine revelation. Very well then, with that as preliminary the Catechism asks, Question 22. What is then necessary for a christian to believe? Answer: All things promised us in the gospel, (a) which the articles of our catholic undoubted christian faith briefly teach us. As they ask what is “necessary” to believe, I understand the catechizers to be communicating that what they are about to give is the basics of Christianity. They intend to stick to the meat and potatoes of our undoubted Catholic Christian faith. The catechism is given as a basic Christianity 101. Now we might find that surprising given that it takes 129 questions in the catechism to give us the basics. We’re used to 30 second sound bites to get us up to speed on any given subject. We think that we can crash course almost any subject and get up to speed in almost no time. But the Catechism, in order to give us just the essentials gives us 129 questions and answers to digest, understand, and own. Of course what is discussed in the Catechism is just the bare essentials. A Christian, having this foundation will learn much much more throughout their whole Christian life and then when they are old and ready to depart they will readily admit that they are but a child in their understanding of their undoubted Catholic Christian faith. It is interesting that what we are required to believe is all that is promised in the Gospel. This teaches us two truths. 1.) Our undoubted Catholic Christian faith is about grasping God’s promises. The Gospel is first and foremost about God’s promises to us. The Gospel is first and foremost what God has done for us. When we teach a Christian what is necessary to believe we are teaching them to rest in God’s promises. We are teaching them that God has done all the saving in Christ and that He promises to save all those who are weary and heavy laden if they will take God at His Word that “all who call upon the name of the Lord shall be saved.” 2.) The “Gospel,” as we shall see, includes believing in doctrines that sometimes are, in our contemporary Church setting, not seen as being necessary to consider. For example, the catechism will be teaching us that it is necessary for us to believe in a robust supernaturalism. In order to believe the Gospel we are required to believe Divine creation, the virgin Birth, that our Lord Christ was resurrected from the grave and that He ascended into heaven. The authors of the catechism did not countenance a hermeneutic that allowed us to try to understand the Scripture apart from the Supernatural and where we find people in the Church who claim Christ but interpret the Bible in order to avoid the supernatural or who use semantic deception to diminish the supernatural there we find people who are out of step with the Catechism and Scripture. That belief is necessary for the Christian is taught in John 20:31 “But these are written, that ye might believe that Jesus is the Christ, the Son of God; and that believing ye might have life through his name.” In question 23 the catechism gives us the Apostles Creed as the statement that they will be breaking down in order to explain to us our undoubted Catholic Christian faith. This Creed comes to us from the life of the early Church and gives 12 affirmations regarding the nature and character of the catholic (universal) Christian faith. Often the Apostles Creed is used in Church services. In some of the branches of Christianity you might even find the Creed being chanted during the worship service. As you know we regularly recite the Apostles Creed whenever the Lord Christ invites us to His table (Eucharist). Question 23. What are these articles? Answer: 1. I believe in God the Father, Almighty, Maker of heaven and earth: 2. And in Jesus Christ, his only begotten Son, our Lord: 3. Who was conceived by the Holy Ghost, born of the Virgin Mary: 4. Suffered under Pontius Pilate; was crucified, dead, and buried: He descended into hell: 5. The third day he rose again from the dead: 6. He ascended into heaven, and sitteth at the right hand of God the Father Almighty: 7. From thence he shall come to judge the quick and the dead: 8. I believe in the Holy Ghost: 9. I believe a holy catholic church: the communion of saints: 10. The forgiveness of sins: 11. The resurrection of the body: 12. And the life everlasting. Since we will be looking closely at each one of these 12 statements we allow the Creed to go uncommented on here. Then in Question 24 they give a brief subdivision of the Apostles Creed. 8. Lord’s Day Question 24. How are these articles divided? Answer: Into three parts; the first is of God the Father, and our creation; the second of God the Son, and our redemption; the third of God the Holy Ghost, and our sanctification. The whole statement of the Apostles Creed is broken down into three subdivisions. One subdivision for each member of the Trinity. The work of God the Father is associated with Creation. Subsumed under His work of creation we will be looking into His work of sustaining, and governing. God’s Providence will be a matter we pay close attention to. The work of God the Son is associated with our Redemption accomplished. The Son was set apart from Eternity to be the Representative and Savior for His people. As such we will be looking at matters like propitiation, reconciliation, atonement, and other doctrines associated with the Son’s work of Redemption. The work of God the Spirit is associate with our Redemption applied. The Spirit, being sent by the Father and the Son, applies the work of Redemption to His people and possesses His people to the end that they go from Christ-likeness to Christ-likeness. Even though we subdivide the Apostles Creed in these three parts we mustn’t be so wooden as to think that the particular work that is assigned to each member of the Trinity finds the other members of the Trinity uninvolved with that work. For example, even though we rightly ascribe Creation to the work of the Father, we can read in Scripture of the Son and Creation, Colossians 1:16 For by Him all things were created, both in the heavens and on earth, visible and invisible, whether thrones or dominions or rulers or authorities—all things have been created through Him and for Him. 17 He is before all things, and in Him all things hold together. Hebrews 2:10 For it was fitting for Him, for whom are all things, and through whom are all things, in bringing many sons to glory, to perfect the author of their salvation through sufferings. And Genesis speaks of the work of the Spirit in creation, Genesis 1:2 The earth was [a]formless and void, and darkness was over the [b]surface of the deep, and the Spirit of God was [c]moving over the [d]surface of the waters. Similar examples could be given for each of the works that are properly ascribed to the members of the Trinity. So, while it is not wrong to think of the Father in relation to his Creator work, or the Son in relation to His Redemption work, or the Spirit in relation to His Sanctifying work it would be wrong to not realize that because of the intimate relationship between each member of the Trinity that when one member is involved in a particular work each member is involved in that work. Each member of the Trinity cooperates in each work.
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Download the iScrap App for FREE and check National Scrap Prices Daily. Are you looking to save money on your car repair? You can quickly locate and contact Durham salvage yards within minutes on the iScrap App. Auto recyclers in Durham listed in our directory are ready to help you find the part you need. When you request salvage car parts for your year, make and model Durham salvage yards will be able to contact you with more information about the part you need such as pricing and availability. Requests from salvage yards in Durham for scrap auto parts will help you save time and money on your auto repair. You can quickly locate the right salvage yard in Durham to contact and buy salvage car parts with the iScrap App. When you are ready to scrap your car for cash you can easily locate an auto wrecker in Durham as well. You can request a car pickup with the Durham auto wrecker listed in our directory. When you request a pick up the salvage yards in Durham will be able to get in touch with you to schedule a day and time for pick up that works for everyone Be sure to check with the auto wrecker that you choose to find out the proper paperwork you will need to sell your car for scrap. Most Durham auto recyclers will require a valid ID and the vehicles title. When you are looking for new ways to make more money on your scrap materials be sure to check out the iScrap App metal forums. On the forums pages you will be able to get in touch with other scrappers like you to exchange scrapping tips and stories with each other. Find the salvage yards in Durham near you with the iScrap App so you can start making more money from your scrap materials today.
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The conductor David Hill talks to ISM faculty members Markus Rathey and Jimmy Taylor about Robert Schumann’s little-known arrangement of Bach’s St. John Passion. We will hear a movement from the work as performed by Yale Schola Cantorum live in Woolsey Hall in 2018. The whole performance is available on the ISM YouTube Channel. David Hill has a long and distinguished career as one of Europe’s leading conductors. He has held appointments as chief conductor of the BBC Singers, musical director of The Bach Choir, chief conductor of Southern Sinfonia, music director of Leeds Philharmonic Society, and associate guest conductor of the Bournemouth Symphony Orchestra. He has been awardee an honorary doctorate by the University of Southampton, and Honorary Fellowship of the Royal School of Church Music, and an honorary membership of the Royal Academy of Music. He has a long list of conducting credits and an extensive discography. On the Yale faculty since 2013, he serves as principal conductor of Yale Schola Cantorum, and participates in the training of student choral conductors. | David Hill’s website Professor Markus Rathey is a specialist in the works of Johann Sebastian Bach, 17th and 18th century music, and the relationship between music, religion, and politics during the Enlightenment. Rathey studied musicology, Protestant theology, and German in Bethel and Münster. He taught at the University of Mainz and the University of Leipzig and was a research fellow at the Bach-Archiv, Leipzig, before joining the Yale faculty in 2003. Rathey’s two recent books, both published in 2016, explore some of the most important works by Johann Sebastian Bach. His book Johann Sebastian Bach’s Christmas Oratorio: Music, Theology, Culture (Oxford University Press 2016) is the first study of this composition in English and it not only sheds new light on Bach’s compositional practice but it also locates the oratorio within the religious and social landscape of eighteenth-century Germany. Rathey’s second recent book is an introduction to Bach’s Major Vocal Works (Yale University Press, 2016). Within the short time since its publication, the book has become a standard work on Bach’s sacred vocal music, praised for its depth but also its accessibility. As one reviewer highlights, it is a prime example for “bringing musicology to the public.” The book also appeared in a Japanese translation in 2017. Earlier books by Rathey include a study of the Baroque composer Johann Rudolph Ahle, titled Johann Rudolph Ahle (1625-1673). Lebensweg und Schaffen (Eisenach, 1999), focusing on the relationship between compositional practice and the music market in the seventeenth century, and a study of C.P.E. Bach’s compositions for the Militia in Hamburg, Kommunikation und Diskurs: Die Bürgerkapitänsmusiken Carl Philipp Emanuel Bachs (Hildesheim, 2009), which explores the pedagogical function of music within the Patriotism discourse in the second half of the eighteenth century. In 2008 he published an edition of the music-theoretical writings by Johann Georg Ahle (Hildesheim, 2008). Professor Rathey has published numerous articles on music by Bach, Mozart, Schütz, Buxtehude and their contemporaries in scholarly journals such as Eighteenth-Century Music, Early Music, Early Music History, Journal of Musicological Research, Bach-Jahrbuch, and Schütz-Jahrbuch. He frequently serves as a commentator on J.S. Bach and on the relationship of music and religion for a number of major media outlets, including The Wall Street Journal, The Economist, and BBC Radio. Rathey is president of the American Bach Society and past president of the Forum on Music and Christian Scholarship. He currently serves on the editorial boards of BACH: Journal of the Riemenschneider Bach Institute and the Yale Journal for Music and Religion. With an extensive repertoire ranging from the medieval period to the twenty-first century, tenor James Taylor devotes much of his career to oratorio and concert literature. As one of the most sought-after Bach tenors of his generation, he has performed and recorded extensively with many of today’s preeminent Bach specialists, including Nicholas Harnoncourt, Philippe Herreweghe, René Jacobs, and Masaaki Suzuki. Since 1993, Taylor has maintained a close relationship with conductor Helmuth Rilling and the International Bach-Academy Stuttgart, performing and teaching master classes worldwide. On several occasions, he has been a juror and consultant for the International Bach-Competition Leipzig. In 2008 he debuted with the New York Philharmonic under the direction of Kurt Masur, singing the role of the Evangelist in Bach’s St. Matthew Passion. Taylor’s career as an oratorio specialist has taken him throughout the United States, South America, Japan, Korea, and Israel, and to virtually all the major orchestras and concert halls of Europe. He is particularly proud to have performed Britten’s War Requiem in the Munich Residence on the sixtieth anniversary of the end of World War II. Taylor has recorded extensively on the Hänssler, harmonia mundi, Limestone, Naxos, and ArkivMusik labels. He joined the Yale faculty in 2005 and serves as coordinator for the voice program in Early Music, Art Song, and Oratorio. Yale Schola Cantorum is a chamber choir that performs sacred music from the sixteenth century to the present day in concert settings and choral services around the world. It is sponsored by Yale Institute of Sacred Music and conducted by David Hill; Masaaki Suzuki is principal guest conductor. Open by audition to students from all departments and professional schools across Yale University, the choir has a special interest in historically informed performance practice, often in collaboration with instrumentalists from Juilliard415. Schola was founded in 2003 by Simon Carrington. In recent years, the choir has also sung under the direction of internationally renowned conductors Matthew Halls, Simon Halsey, Paul Hillier, Stephen Layton, Sir Neville Marriner, Nicholas McGegan, James O’Donnell, Stefan Parkman, Krzysztof Penderecki, Helmuth Rilling, and Dale Warland. In addition to performing regularly in New Haven and New York, the ensemble records and tours nationally and internationally. Schola’s 2018 recording on the Hyperion label featuring Palestrina’s Missa Confitebor tibi Domine has garnered enthusiastic reviews. A live recording of Heinrich Biber’s 1693 Vesperae longiores ac breviores with Robert Mealy and Yale Collegium Musicum received international acclaim from the early music press, as have subsequent CDs of J. S. Bach’s rarely heard 1725 version of the St. John Passion and Antonio Bertali’s Missa resurrectionis. A recording on the Naxos label of Mendelssohn and Bach Magnificats was released in 2009, and recent years have seen the release of two CDs by Delos Records. Most recently, Hyperion released Schola Cantorum performing a chamber version of the Brahms Requiem; recordings of the music of Roderick Williams and Reena Esmail are forthcoming. On tour, Schola Cantorum has given performances in England, Hungary, France, China, South Korea, Italy, Greece, Turkey, Japan, Singapore, Russia, Estonia, Latvia, India, Spain, and Scandinavia.
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The Cobra Effect is a great example of unintended consequences that arise when solving a problem. We’ll highlight the Cobra Effect and other examples of unintended consequences both in articles and a video and mention two Six Sigma tools that can aid in surfacing potential unintended consequences before they occur. The Cobra Effect and Unintended Consequences We’ll start with the video as it does an excellent job of introducing the Cobra Effect from 1911 India and gives examples of other unintended consequences. - Rats in Hanoi - Incentives and Bonuses in Sales - Call Center Calls - 2008 Sub-prime Crisis The video then goes on to discuss why unintended consequences occur and offers three ways of how to prevent them. - Diversity: Obtain Inputs from As Diverse a Group of People as Possible - Take the Stakeholders Into Account - Think in Terms of Complex Systems The video concludes with how the original cobra effect could have been avoided using the three ways mentioned to avoid them. You can watch the video from Free Science 365 at the following link. Using Process Mapping to Identify Unintended Consequences In his blog post titled “The Process Improvement Catch 22: The Law of Unintended Consequences” author Terry Giles briefly discusses the use of process mapping in surfacing unintended consequences You can read his blogpost here. Unintended Consequences and Risky Thinking In a comprehensive paper titled “Unintended Consequences and Risk(y) Thinking: The Shaping of Consequences and Responsibilities in Relation to Environmental Disasters” authors Rolf Lidskog and Daniel Sjödin discuss how the development of risk analysis and the adoption of risk language have substantial implications for how to understand and evaluate unintended consequences. They analyze a human-caused severe wildfire to illustrate and expand the understanding of unintended consequences. They discuss the use of differentiation, recognizability, responsibility, and framing to improve the analysis of unintended consequences and use the wildfire disaster for illustration. Copy and paste the following link into your browser to access the paper. The Law of Unintended Consequences: Examples, Causes, and Mental Models A blogpost titled “The Law of Unintended Consequences: Shakespeare, Cobra Breeding, and a Tower in Pisa” from the Farnam Street Blog lists several cases of unintended consequences and finishes with a discussion of the causes of unintended consequences and mental models for avoiding or minimizing unintended consequences. You can access the blogpost here. Using the Reverse Fishbone Diagram and Pilot Projects to Surface Potential Unintended Consequences There are methods within the Lean Six Sigma toolbox that aid in surfacing potential unintended consequences before they occur. The Reverse Fishbone Diagram is one such tool as it is used to analyze the impacts of a change. We covered it in a previous blog post. Running a pilot project in Lean Six Sigma project implementation is one way to determine potential unintended consequences before introducing the final project recommendations. In fact, consider using the Reverse Fishbone during the Pilot Project implementation in the Improve Phase of your Lean Six Sigma project in order to analyze the effects of your improvement solution(s).
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How to Fix a CD Stuck in a Sony Five Disc CD Changer By Darla Ferrara Updated February 10, 2017 Sony created a CD player that features a 5-disc carousel where you can load both CD-R and CD-RW formats. This means the player from Sony can use your favorite artist's album or one you mix personally. The design of a five disc CD player is not that different from a unit that only holds one disc, but the tray is bigger. When a disc gets stuck, the goal is to get the tray to eject from the machine or to expose the platform and remove the troublesome disc. Push in the door on the front of the player that covers the CD tray. Press in the tray slightly using the fingers from the hand holding the door open. The tray is spring-loaded so you will feel a small give when you press. Use your other hand to hold down the "Eject" button, which is next to the tray on the front of the player, at the same time. Once the button is down, let go of the tray and see if it ejects. Push down gently on the tray if it still does not come free and repeat the process of pressing the eject button. Unplug the player from the wall outlet if the tray remains stuck. Turn the unit over and remove the screws from the top cover using your screwdriver. Set the screws aside. Flip the player back over and gently pull off the cover. This exposes the CDs sitting in the tray. Remove all of the discs and reattach the cover. If discs continue to stick in your player, it may require service. Do not remove the cover with the machine plugged in to avoid the potential of electric shock. Writing since 1999, Darla Ferrara is an award-winning author who specializes in health, diet, fitness and computer technology. She has been published in "Mezzo Magazine" and Diet Spotlight, as well as various online magazines. Ferrara studied biology and emergency medical technology at the University of Nebraska and Southeast Community College.
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According to a recent survey of Defined Benefit pension plan sponsors, 89% of plan sponsors believe that Canada's pension system is either poorly positioned or average in its ability to meet the future needs of Canadians. Nearly half of respondents identified investment risk as their primary concern. The risk of pension shortfalls was second with nearly 36% of respondents identifying this as their primary concern. Despite the generally negative results, 72% of respondents felt that Canada's pension system is either the same or better than other pension systems around the world. Only 8% of respondents believe Canada's pension system is worse.
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Employers are responsible for organising the overall process of work, also for organising work stations and providing the necessary equipment for employees to work. For that reason employees are not duty-bound to use their own tools and equipment when doing their jobs, and this includes remote work. The regulations on countering COVID-19 do not govern the reimbursement of the expenses of remote work Thus far the regulations of the special law have not introduced any solution to cover the incremental costs incurred by employees due to working remotely. That is why the rules in place until now should be referenced. The costs of remote work should be refunded by employers according to general rules The costs incurred by employees in connection with working remotely should be reimbursed just like other business expenses based on evidence they have incurred them. Employees applying for reimbursement should present credible evidence of having incurred costs and substantiate their connection with the work they do, if requested. The cost reimbursement may also include the elevated consumption of utilities. If employers refund the costs of buying the equipment needed to work remotely, then this equipment should in principle become part of their assets. If employers decide to give the equipment to their employees, then the value of that equipment should be treated as income received by the employees. Tax exempt equivalent The Personal Income Tax (PIT) Act contemplates a tax exemption for cash equivalents paid to employees for the tools, materials and equipment they own and use to do their work. We would like to point out that an equivalent is the amount corresponding to the costs employees actually incur. For that reason, it is important for employers who intend to apply this exemption to be diligent in checking the expense employees incur when they use their private equipment for business purposes. An equivalent should not include the elevated costs of consuming utilities, Internet access and the coffee and tea employees consume when they do remote work.
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Faithful to the work Jesus commissioned, Pastor Junie and his wife, Fatty (Fatima), have devoted their lives to the cause of helping people discover God. They moved to Canada in 1999 to lead a church focused on loving and leading people to Jesus. Filled with compassion and love for Canada, Pastor Junie, along with the support of Fatty, presently serves as the Lead Pastor of the International Worship Centre (IWC) with 6 Sites in Manitoba. IWC continues to grow through the many outreaches at all five sites, including sports outreach programs at the Youth Development Centre. His passion and mission to reach Canada one person at a time is evident in his desire to mentor the next generation of leaders with a plan to plant churches all across Canada. More importantly, his heart's joy is to spend time with his wife and family: their daughter, Ruth, son-in-love, Zach, and son, Isaac. Pastor Junie and Fatty enjoy being a grandpa (Wowo) and grandma (Wowa) to Caleb Brave and Zoe Joy, children of Ruth and Zach.
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On Saturday, January 13, 2018, IZOLYATSIA invites everyone to join the first group initiative by cultural institutions based in Podil. The Old New Year, ancient Ukrainian festivities known as Malanka, or simply January's last festive weekend are a perfect occasion to get together and have some fun. That is why IZOLYATSIA and IZONE Creative Community joined efforts with Port Creative Hub, Ya Gallery, Dymchuk Gallery, and BURSA Gallery to prepare a series of free cultural events for all audiences as well as a special itinerary to make the road between galleries more interesting and entertaining. The KOZA Podil Alternative Cultural Route will start at 12 PM at the IZONE Creative Community (vul. Naberezhno-Luhova 8, Second Floor) and continue throughout the day at other locations. At IZONE, you will get a special map. Each institution will stamp it, and the first three persons to have all the seals and reach BURSA Gallery will get presents! For detailed programme and schedule, please visit the official Facebook event.
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Lottery UK Online Overview The UK Lottery is a popular game for its ability to make millionaires. It can be played online as well. The game is drawn twice a week on Wednesdays and Saturdays. How the UK Lottery Works Each player must select 6 numbers on their ticket from a selection of the numbers 1-49. When the draw takes place, six numbers are selected along with one bonus number. Due to the relatively small payout percentage, we do not recommend this lottery. There are plenty of other international lottery games available online with better payouts and higher jackpots. Winning the UK Lottery You must match a minimum of three numbers to the main numbers drawn in order to win a prize. The bonus number is only relevant if you match at least five of the main numbers in the draw. It is simple to claim your winnings. If you win up to €2500, you will be paid directly to your lottery player account here on our site. For wins higher than €2.500, our customer support department will contact you and arrange a direct payout from the lottery company. Approximately 45% of all UK lotto funds go towards prize money. If you match six of the main numbers, you will be paid out 52% of the pool’s fund; if you match five main numbers, plus the bonus number you will be paid out 16% of the remaining pool’s fund; if you match five main numbers you will be paid out 10% of the remaining pool’s fund; if you match four main numbers you will be paid out 22% of the remaining pool’s fund and if you match 3 main numbers you will generally be paid out £10. The UK Lotto also offers online instant win games. Playing the UK Lottery Online You are able to play the UK Lotto online which makes it more accessible and convenient. You no longer have to go out to buy a UK lotto ticket from a retailer; you can now buy tickets from the comfort of your own home, and it is not dependent on your living in the UK. In order to play the UK lotto online and from outside the UK, you will need to click the above banner for the UK lottery. You simply need to register and then complete an online payment. Why most international lottery jackpots are more attractive than the UK Lottery - The jackpots are much higher with the international lotteries (check the amounts in the banner on top) - UK Lotto only hands out only 45% of the funds as winnings - On our website, you have a variety of mega-lotteries and huge jackpots to choose from!
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I was very pleasantly surprised when I received a message from Paula Gorry, UK Demonstrator Developement Manager (DDM) yesterday. She said that the Thank You So Much note card I submitted as part of the Stampin’ Up! # simplestamping challenge has won a prize! Normally the prizes for something like this is a small product, maybe some ribbon, or trinkets, which is always gratefully received. But the big thrill is actually knowing one of my cards has been selected! If I remember correctly, this challenge is running for several months, so I can have another try! The colours for today’s card have taken me well out of my comfort zone. I saw the ready stamped wreath sitting on top of a small pile of stamped images and die cuts, and decided to see what I could do with it. I reached for my box to get a Whisper White Cardstock (CS) top layer. When I put the wreath against it, I thought it looked very pale. I took a piece of Crumb Cake instead! At this stage I had a Crumb Cake layer and a Tranquil Tide wreath on Whisper White. Normally I would have gone for a Crumb Cake base, with a middle layer of Whisper White but yesterday I started looking at other options. Do you remember the Colour Coach we used to sell? I still have mine and took it out to see if I could find some inspiration. Very surprisingly I chose Cajun Craze. I say surprisingly because in my book this colour comes under the heading of orange! I’m very pleased with the finished result, which tells me I should get out of my comfort zone more often. I embossed the top layer using the Pinewood Planks Dynamic Embossing Folder, to look like a door! I did toy with the idea of adding some furniture like hinges, but decided against it! The bow has been stamped in Cajun Craze Ink and then fussy cut. The Cajun Craze flowers on the wreath are from the Detailed Deer Framelits Dies. I have layered the flowers with cut out petals, on top of the solid flowers, painted them with Wink of Stella Clear Glitter, and topped with a small pearl. The tiny bows are from the Farmhouse Framelits, and have also been painted with Wink of Stella. The stentiment is from Snowflake Sentiments Stamp Set. I used Tranquil Tide Ink, and stamped off once. Both the sentiment and the wreath have been adhered with Dimensionals. To decorate inside, I used some leftover Cajun Craze bows plus some white ones I’d been experimenting with. As I said earlier, out of my comfort zone, but I’m not unhappy with the result. I’m off to the hairdressers this morning for a little bit of me time! I have a small amount of shopping I need to do, and then stop at the chemist. Then I’ll be back in the warmth again! I hope you have a lovely day, and I’ll be back tomorrow. In the meantime, happy crafting. Products used: please click on any image to be taken to my 24/7 Online Stampin’ Up! shop.
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Image Mosaics For Assignment 2, you will implement an image stitcher that uses image warping and homographies to automatically create an image mosaic. We will focus on the case where we have two input images that should form the mosaic, where we warp one image into the plane of the second image and display the combined views. This problem will give some practice manipulating homogeneous coordinates, computing homography matrices, and performing image warps. For simplicity, we’ll specify corresponding pairs of points manually using mouse clicks. Note: There are some built-‐in Matlab functions that could do much of the work for this project. However, to get practice with the workings of the algorithms, we want you to write your own code. Specifically, you may not use any of these functions in your implementation: cp2tform, imtransform, tformarray, tformfwd, tforminv, maketform. Provided files: Two image files that can be used for the mosaic. What You Have to Do Task 1 (15 points) Getting correspondences: Write code to get manually identified corresponding points from two views. Look at Matlab’s ginput function for an easy way to collect mouse click positions. The results will be sensitive to the accuracy of the corresponding points; when providing clicks, choose distinctive points in the image that appear in both views. Task 2 (20 points) Computing the homography parameters: Write a function that takes a set of corresponding image points and computes the associated 3 x 3 homography matrix H. This matrix transforms any point pi in one view to its corresponding homogeneous coordinates in the second view, pi’, such that λ* pi = H * pi’ Note that pi and pi’ are both vectors with 3 elements. The function should take a list of pairs of corresponding points (what is the minimum number of points you need?) from the two views, where each point is specified with its 2d image coordinates. Useful Matlab functions: ‘\’ operator (help mldivide), reshape Verify that the homography matrix your function computes is correct by mapping the clicked image points from one view to the other, and displaying them on top of each respective image. Be sure to handle homogenous and non-‐homogenous coordinates correctly. Task 3 (20 points) Warping between image planes: Write a function that can take the recovered homography matrix and an image, and return a new image that is the warp of the input image using H . Since the transformed coordinates will typically be sub-‐pixel values, you will need to sample the pixel values from nearby pixels. Feel free to use the sampleBilinear.m you developed for the first assignment. For color images, warp each RGB channel separately and then stack together to form the output. To avoid holes in the output, use inverse warp rather than direct mapping. To compute the bounding box of the destination image, you will need to warp the points from the source image into the reference frame of the destination. Then sample all points in that destination bounding box from the proper coordinates in the source image. Note that transforming all the points will generate an image of a different shape / dimensions than the original input. It is ok to have some areas of the new image be black (0). Useful Matlab functions: round, interp2, meshgrid, isnan. Task 4 (20 points) Create the output mosaic: Once we have the source image warped into the destination image’s frame of reference, we can create a merged image showing the mosaic. Create a new image large enough to hold both (registered) views; overlay one view onto the other, simply leaving it black wherever no data is available. Don’t worry about artifacts that result at the boundaries. You are free to use a method/convention of your own choosing for the overlap areas. Task 5 (25 points) After writing and debugging your system: 1. [5 pts] Apply your system to the provided pair of images, and display the output mosaic. 2. [10 pts] Show two additional examples of mosaics you created using images that you have taken. You can make a mosaic from two or more images of a broad scene that requires a wide angle view to see well. Or, make a mosaic using two images from the same room where the same person appears in both. 3. [10 pts] Warp one image into a “frame” region in the second image. To do this, let the points from the one view be the corners of the image you want to insert in the frame, and the let the corresponding points in the second view be the clicked points of the frame (rectangle) into which the first image should be warped. Use this idea to replace one surface in an image with an image of something else. For example -‐-‐ overwrite a billboard with a picture of your dog, or project a drawing from one image onto the street in another image, or replace a portrait on the wall with someone else’s face, or paste a Powerpoint slide onto a movie screen, … For all examples, play around a bit with the choice of points for the correspondence pairs until you get a reasonable alignment. [OPTIONAL] Extra credit Implement RANSAC for robustly estimating the homography matrix from noisy correspondences. Your function should be able to handle more than 4 point correspondences. Show with an example where it successfully gives good results even when there are outlier (bad) correspondences given as input. Compare the robust output to the original (non-‐RANSAC, only 4 point correspondences) implementation where all correspondences are used. Note: feel free to attempt using David Lowe’s SIFT Matlab demo (http://www.cs.ubc.ca/~lowe/keypoints/siftDemoV4.zip). Warning: it only works in Linux and Windows, it does not work on Mac. The result of calling the sift.m function will be 2 vectors, one of features and one of keypoints. Make sure you understand what is saved in these two variables so that you can potentially use them for the RANSAC implementation. If you can’t get SIFT to work, you will need to select make than 4 pairs of points using the function developed in Task 1. Submitting the assignment: Make sure each script or function file is well commented and it includes a block comment with your name, course number, assignment number and instructor name. Zip all the .m and image files together and submit the resulting .zip file through Moodle as Assignment 2 by Friday, September 30th, by 11:55pm. Acknowledgement: project description and test images courtesy of Kristen Grauman, University of Texas at Austin. Tips: • It can be useful when debugging to plot the corners and clicked points from one view on top of the second view after transforming them via H. Use axis([minx, maxx, miny, maxy]); to adjust the viewing window so that you can see all points. • You will need the inverse of the homography matrix to transform “backwards”. • Be aware that Matlab’s image (matrix) indices are specified in (row,col) order, i.e., (y,x), whereas the plot and ginput functions use (col,row) order, i.e., (x,y). • Check the order of the clicked corresponding points, to make sure your code uses the intended corresponding point pairs. • As usual, be careful with how images are cast for computations and display (double vs. uint8). In particular, for your sampleBilinear.m function, be sure to pass a matrix of doubles for the image input. • When collecting your own images, be sure to either maintain the same center of projection (hold the camera at one location, but rotate between views), or else take shots of a scene with a large planar component (a building, maybe). In either case, use a static scene. Textured images that have distinctive points you can click on are good.
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Reduced virulence in tigecycline-resistant Klebsiella pneumoniae caused by overexpression of ompR and down-regulation of ompK35 Journal of Biomedical Science volume 30, Article number: 22 (2023) The development of tigecycline resistance in hypervirulent Klebsiella pneumoniae strains has resulted in decreased virulence that is associated with reduced production of capsular polysaccharides (CPS). In this study, we investigated the mechanisms that link tigecycline susceptibility to decreased virulence. We compared transcriptomes from tigecycline-susceptible wild-type strains and tigecycline-resistant mutants using mRNA sequencing. ompR-overexpressed and ompR-deleted mutants were constructed from wild-type strains and tigecycline-resistant mutants, respectively. Antibiotic susceptibility tests were performed, and string tests and precipitation assays were conducted to identify phenotypic changes related to tigecycline susceptibility and ompR expression. Bacterial virulence was assessed by serum resistance and Galleria mellonella infection assays. Transcriptomic analyses demonstrated a significant decrease in the expression of ompK35 in the tigecycline-resistant mutants. We observed that tigecycline-resistant mutants overexpressed ompR, and that the expression of ompK35 was regulated negatively by ompR. While tigecycline-resistant mutants and ompR-overexpressed mutants exhibited reduced hypermucoviscosity and virulence, deletion of ompR from tigecycline-resistant mutants restored their hypermucoviscosity and virulence. In hypervirulent K. pneumoniae strains, ompR expression, which is regulated by exposure to tigecycline, may affect the production of CPS, leading to bacterial virulence. Klebsiella pneumoniae is one of the significant gram-negative pathogens that cause a variety of diseases including intra-abdominal infections, pneumonia, urinary tract infections, and pyogenic liver abscesses . Several virulence factors, capsules, lipopolysaccharides, siderophores, and fimbriae have been identified in K. pneumoniae . Particularly, the capsule is widely recognized as a major virulence factor that contributes to its defense against environmental pressures and host immune responses, as well as to antibiotic resistance [3, 4]. Due to the increased antimicrobial resistance in K. pneumoniae, tigecycline is often used as a last-resort antibiotic to combat multidrug-resistant K. pneumoniae . However, tigecycline resistance has been reported with increased frequency in K. pneumoniae during treatments with tigecycline, or even without exposure to tigecycline [6, 7]. It has been known that resistance to tigecycline is mainly attributed to the overproduction of efflux pumps such as AcrAB and OqxA, or to mutations in efflux pump regulator genes such as ramA, soxR, marR, and acrR . In gram-negative bacteria, the outer membrane proteins play a crucial role in bacterial virulence and are also associated with antibiotic resistance . It is well-known that K. pneumoniae generates two major porins: OmpK35 and OmpK36, the levels of which are affected by a variety of environmental conditions such as osmolarity, temperature and pH . The tigecycline-resistant K. pneumoniae isolates exhibited significantly decreased expression of the porin OmpK35, compared to susceptible isolates . In addition, the development of tigecycline resistance in hypervirulent K. pneumoniae resulted in decreased virulence associated with reduced CPS . However, it is not known why CPS and virulence decrease in the tigecycline-resistant K. pneumoniae strain. In this study, we investigated the mechanism for the association between OmpK35 and tigecycline resistance. We constructed mutants with deleted or overexpressed ompR, a negative regulator of ompK35, and compared the mucoviscosity, virulence, and gene expression between wild-type K. pneumoniae strains and their ompR mutants. Materials and methods Bacterial strains, plasmids, and culture conditions In this study, two K. pneumoniae strains, 109 and 200, were used that were isolated from the blood of South Korean patients . Their capsular serotype was determined to be K1 and the 109 and 200 exhibited hypermucoviscous. Both strains belong to the multilocus sequence type 23 (ST23) and were susceptible to tigecycline. The tigecycline-resistant mutants 109-IR and 200-IR were derived from tigecycline-susceptible K. pneumoniae strains by methods previously described . Briefly, the susceptible strains were subcultured in Luria–Bertani (LB) broth with a serially increasing concentration of tigecycline (0.5 to 64 mg/L). All K. pneumoniae strains, mutants and plasmids that were used to construct mutants are presented in Table 1. All bacterial strains were grown in LB broth with shaking at 37 °C, and tigecycline-resistant mutants were cultured in media with 64 mg/L tigecycline. Where appropriate, gentamicin (30 mg/L) was added to the growth medium, and isopropyl-β-d-thiogalactopyranoside (IPTG) was added to 109/ompR and 200/ompR at a concentration of 0.25 mM, and to 109-IR∆ompR-C and 200-IR∆ompR-C at a concentration of 1 mM to induce OmpR. Transcriptomic analysis by mRNA sequencing Transcriptome profiling was performed to contrast the expression profiles between tigecycline-susceptible and resistant strains. For mRNA sequencing, all isolates were overnight cultured with vigorous shaking (220 rpm) at 37 °C and diluted into fresh LB broth (1:100). The RNA samples were extracted from mid-log phase bacterial cultures using a Qiagen RNeasy Mini kit (Qiagen, Hilden, Germany), according to the manufacturer’s instruction. The TURBO DNA-free™ Kit (Invitrogen, MA, USA) was used to remove the contaminated DNA in RNA samples and we obtained mRNA from isolates. After isolation of RNA, cDNA was synthesized and sequencing libraries were generated in strand-specific manner according to the Illumine standard protocol for high-throughput sequencing. Library construction and sequencing were performed at Macrogen Inc. (Seoul, South Korea) using an HCS 3.3.52 Software for Illumina HiSeq 4000 sequencing system. The 101 bp paired-end raw reads were filtered and trimmed using Fase QC (version 0.11.7) and Trimmomatic (version 0.38). Expression levels of mRNA were measured as reads per kilobase per million sequence reads (RPKM), which considers the gene length for normalization. The complete genome sequence of K. pneumoniae NTUH-K2044 was used for aligning reads. The GenBank accession number of NTUH-K2044 is AP006725. Construction of ompR deletion mutants The ompR-deleted mutants were generated from 109-IR and 200-IR using the Lambda-Red recombinase method and the pKD46 plasmid (Table 1). The pHK1014 plasmid was introduced into 109-IR and 200-IR by electroporation. Transformants were selected using 30 mg/L gentamicin, and then bacterial colonies were confirmed using the primer pairs pKD46-repA101-F/pKD46-repA101-R (Table 2). The kanamycin resistance gene (KmR) in pHK1009 was amplified using the primer pairs Del-ompR-F/Del-ompR-R that are upstream and downstream to the ompR gene (Table 2). The KmR amplicon was transformed into 109-IR and 200-IR which harbored pHK1014. Transformants were selected using 50 mg/L kanamycin, and bacterial colonies were confirmed using the primer pairs Checkpri-ompR-F/Checkpri-ompR-R (Table 2). Cloning of ompR and complementation to mutants For construction of the ompR expression vector, ompR was amplified from chromosomal DNA from the strain 109 using PCR and the primer pairs ompR-F/ompR-R (Table 2). The PCR product was purified using the extraction kit (iNtRON, Seongnam, Korea), digested with BamHI and ligated into a pHK251 precut using the same restriction enzyme. To confirm the mutation in ompR, Sanger DNA sequencing was performed. The pSY005 plasmid was electroporated into strains 109 and 200 for overexpression of ompR and it was also transformed into 109-IR∆ompR and 200-IR∆ompR for complementation by electroporation. The transformants were then plated on LB agar containing 30 mg/L gentamicin for selection. Antimicrobial susceptibility testing Antimicrobial susceptibility testing was performed in accordance with the FDA guideline (https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021821s026s031lbl.pdf, susceptible, MIC ≤ 2 µg/mL; intermediate, MIC = 4 µg/mL; and resistant, MIC ≥ 8 µg/mL), since no tigecycline breakpoints exist in the Clinical Laboratory Standards Institute guideline for K. pneumoniae. The minimum inhibitory concentration (MIC) of tigecycline was determined by broth microdilution using Escherichia coli ATCC 25922 as the reference strain. All tests were performed in duplicate. String tests and precipitation assays To conduct string tests, all strains were inoculated overnight on LB agar plates at 37 °C and bacterial colonies on plates were extended using a loop. Hypermucoviscosity was determined to be positive when the strain produced a stretched string more than 5 mm in length using a loop . Precipitation assays were performed by centrifugation of the cultures. As the supernatant of hypermucoviscous strains remain dense after centrifugation, the supernatant density of centrifuged cultures can be a quantitative indicator of hypermucoviscosity . Prior to centrifugation, all bacterial strains were cultured in LB broth at 37 °C overnight with shaking. The samples were centrifuged at 2000×g for 10 min then the bacteria were suspended and diluted until the optical density at 600 nm (OD600) reached 4. The optical densities (OD) of the supernatants were measured at OD600. All tests were performed three biological replicates per strain. Serum resistance assay Serum resistance assays were performed to evaluate the resistance against killing by normal human serum (NHS) using a previously described method with slight modifications. All strains were incubated overnight in LB broth at 37 °C with shaking and diluted 1:100 with fresh LB media and grown until the mid-log phase. Twenty-five μL of the bacterial solution were mixed with 75 μL of NHS in microtubes. Heat-inactivated human serum was used as a control to determine the ability to eliminate bacteria by NHS. The mixtures were incubated for 3 h with shaking and plated on LB agar after being serially diluted with phosphate buffered saline (PBS) for colony counting. For all strains, three independent tests were performed. Galleria mellonella infection assays Galleria mellonella larvae were purchased from the Sworm Corp. (Cheonan, South Korea). The G. mellonella larvae were kept at room temperature in the dark with food for ten days before use. Larvae with weights of approximately 150–200 mg were selected for further experiments. Bacterial infections of G. mellonella were performed as previously described with minor modifications . Overnight bacterial cultures were harvested by centrifugation at 16,000 × g for 2 min then washed with 10 mM PBS. Bacterial cultures were adjusted with PBS to a McFarland standard of 0.5. The larvae were then infected with 10 μL of bacterial solutions by injection into the larvae’s last right proleg using an ultra-fine needle (BD Biosciences, San Jose, CA, USA). A PBS injection was used as a negative control, and K. pneumoniae strain ATCC 43816 as a positive control of hypermucoviscous strain. Ten larvae were infected with each bacterial strain and the viability of the larvae was examined until 72 h post infection. The experiments were performed three times independently. RNA extraction and quantitative RT-PCR To measure the relative fold changes of expression of ompK35 and ompR in the strains, quantitative real-time PCR (qRT-PCR) was performed. Overnight cultures of bacteria were inoculated into fresh LB broth and incubated at 37 °C with shaking until mid-log phase. Then, RNA was extracted using a Qiagen RNeasy Mini kit (Quiagen, Hilden, Germany) according to the manufacturer’s instructions. Contaminated DNA was eliminated from RNA samples using a TURBO DNA-free™ Kit (Invitrogen, MA, USA) and the reverse transcription reactions were conducted using a reverse transcription premix kit (iNtRON, Seongnam, South Korea). qRT-PCR was performed using TB Green Premix Ex Taq (TaKaRa, Shiga, Japan) with the QuantStudio 6 Flex Real-Time PCR system (Applied Biosystems, CA, USA) using the primers listed in Table 2. The expression levels were determined by the 2−ΔΔCT method using the rpoB gene as a reference. The qRT-PCRs were performed three times and each sample was analyzed in duplicate. Statistical analyses of all experiments were performed to assess the significance of the differences using Student’s t-test, a one-way ANOVA with Tukey’s multiple comparisons test, and a nonparametric Kruskal–Wallis test followed by Dunnett’s multiple comparison test with Prism v8.3 for windows (GraphPad Software, San Diego, CA, USA). P values of < 0.05 were considered to be statistically significant (*, p < 0.05; **, p < 0.001, ***, p < 0.0001). Differentially expressed genes in the chromosome of Klebsiella pneumoniae The chromosomal genes differently expressed in both tigecycline-resistant mutants (109-IR and 200-IR) were filtered with the criteria of fold-change ≥ 2. The filtered genes were categorized on the basis of the classification of clusters of orthologous groups (COGs) (Fig. 1). As a whole, 252 genes were up-regulated and 214 genes were down-regulated both in tigecycline-resistant mutants compared with the wild-type strains. Especially, 127 genes of metabolism pathway including carbohydrate transport and energy production were overexpressed. Table 3 lists the top 10 genes with the highest differentially expressed genes in the tigecycline-resistant mutants compared with wild-type and tigecycline-susceptible K. pneumoniae strains. From the list we noted that ompK35 encodes a trimeric porin OmpK35, which is a homolog of OmpF in Escherichia coli. OmpK35 has been known to be associated with antibiotic resistance and virulence, along with another porin, OmpK36 . mRNA expression of ompK35 and ompR Using qRT-PCR, we measured mRNA expression of ompK35 and ompR, a repressor of ompK35 under high osmolar environments in E. coli in each of two wild-type strains (109 and 200) and in the tigecycline-resistant mutants 109-IR and 200-IR. As indicated by transcriptomic analysis, ompK35 was down-regulated significantly in the tigecycline-resistant mutants 109-IR and 200-IR (p = 0.0108 and 0.0034, respectively) (Fig. 2A). ompR was up-regulated significantly in 109-IR and 200-IR, compared with their susceptible parental strains (p, 0.0005 and 0.0069, respectively) (Fig. 2A). We then examined the change in ompR expression with increasing tigecycline concentrations in tigecycline-resistant mutants. As the concentration of tigecycline increased, the expression of ompR also increased gradually in both mutants (Fig. 2B). Figure 2C shows that ompR expression is well-regulated by the addition of IPTG. The ompR-overexpressed mutants in the presence of IPTG exhibited significantly decreased expression of ompK35 (Fig. 2D). Expression of ompK35 increased slightly in the ompR-deleted mutants 109-IR∆ompR and 200-IR∆ompR, compared with the tigecycline-resistant mutants 109-IR and 200-IR (p, 0.0129 and 0.0011, respectively). The complementation of ompR and the induction of its expression in ompR-deleted mutants (109-IRΔompR-C and 200-IRΔompR-C) led to decreased expression of ompK35 (Fig. 2D). These results confirmed the role of OmpR as a repressor of ompK35. The MIC for tigecycline increased eightfold in the ompR-overexpressed mutants 109/ompR/IPTG(+) and 200/ompR/IPTG(+), compared to those of tigecycline-susceptible, wile-type K. pneumoniae strains (Table 4). The tigecycline-resistant mutants exhibited very high levels of tigecycline resistance (MICs > 64 mg/L), and the MICs decreased dramatically in the ompR inactivated mutants 109-IR∆ompR and 200-IR∆ompR (4 and 8 mg/L, respectively). However, complementation of ompR did not increase the tigecycline susceptibility. To evaluate the role of ompR on the production of mucoviscosity in K. pneumoniae, we evaluated the changes in colony phenotypes in the mutants. The tigecycline-susceptible strains 109, 200, 109/ompR/IPTG(‒), and 200/ompR/IPTG(‒) displayed large and glossy colony morphologies, while the tigecycline-resistant mutants 109-IR and 200-IR exhibited small and matt colony phenotypes (Fig. 3A). The ompR-overexpressed mutants 109/ompR/IPTG(+) and 200/ompR/IPTG(+) also exhibited small and matt colonies, as observed with 109-IR and 200-IR (Fig. 3A). In the ompR-deleted mutants from the tigecycline-resistant strains 109-IR∆ompR and 200-IR∆ompR, large and glossy colony shapes were observed, compared with 109-IR and 200-IR. The small and matt colony phenotypes of 109-IR and 200-IR were restored by complementation with ompR, 109-IR∆ompR-C, and 200-IR∆ompR-C (Fig. 3A). The tigecycline-susceptible wild-type strains 109 and 200 exhibited a phenotype of hypermucoviscosity, ranging from 24 to 29 mm in the string test; while the ompR-overexpressed mutants 109/ompR/IPTG(+) and 200/ompR/IPTG(+) exhibited significantly reduced lengths of stretched strings, an average of 9 mm for both (P, < 0.0001 and 0.0005, respectively) (Fig. 3B). The tigecycline-resistant mutants 109-IR and 200-IR produced string lengths of 6–8 mm; however, the string lengths of the ompR-deleted mutants 109-IR∆ompR and 200-IR∆ompR increased dramatically to 23 mm and 21 mm, respectively (p, < 0.0001 for both). Complementation with ompR, 109-IR∆ompR-C and 200-IR∆ompR-C, reduced the length of stretched strings to those of tigecycline-resistant mutants (Fig. 3B). Mucoviscosity in the K. pneumoniae strains was determined by measuring the OD at 600 nm of the supernatants after centrifugation. The tigecycline-susceptible wild-type strains 109 and 200 produced turbid and poor sediments due to hypermucoviscosity that causes extreme stickiness (Fig. 3C). The ompR-overexpressed mutants 109/ompR/IPTG(+) and 200/ompR/IPTG(+), and the tigecycline-resistant mutants 109-IR and 200-IR produced clear supernatants after centrifugation, unlike the dusty appearance observed with 109, 200, 109/ompR/IPTG(‒), and 200/ompR/IPTG(‒) (Fig. 3C). The 109-IR∆ompR and 200-IR∆ompR mutants produced a turbid appearance, which reverted to a clear appearance by complementation with ompR (Fig. 3C). The measurement of optical density confirmed the visual observations (Fig. 2D). The overexpression of ompR or the development of tigecycline resistance lowered the turbidity of supernatants significantly, that is, the mucoviscosity. To explore the relationship of ompR with virulence in K. pneumoniae, bacterial survival rates were evaluated against NHS (Fig. 4). The ompR-overexpressed mutants, 109/ompR/IPTG(+) and 200/ompR/IPTG(+), showed significantly decreased survival rates against serum, compared to the wild-type and the tigecycline-susceptible strains. The tigecycline-resistant mutants also exhibited very low survival rates against serum, which has been reported previously . Deletion of ompR in the tigecycline-resistant mutants 109-IR∆ompR and 200-IR∆ompR increased the serum resistance (p, 0.0012 and 0.0026, respectively), and the survival rates of ompR-complemented mutants were diminished. Survival of G. mellonella larva Most of the G. mellonella larva were killed within 72 h by the strains 109 and 200, as by hypervirulent K. pneumoniae strain ATCC 43816 (Fig. 5A and B). The G. mellonella larva survived significantly longer using the ompR-overexpressed mutants 109/ompR/IPTG(+) and 200/ompR/IPTG(+) compared to the wild-type strains (p, 0.0093 and 0.0009, respectively). The tigecycline-induced resistant mutants 109-IR and 200-IR exhibited dramatically increased survival rates with G. mellonella larva, compared to the wild-type and the tigecycline-susceptible strains (p, < 0.0001 and 0.0001, respectively) (Fig. 5A and B). Their survival rates were reduced by deletion of ompR in the tigecycline-resistant mutants and were restored by complementation with ompR (Fig. 5C and D). Previously, we demonstrated that in vitro-induced tigecycline-resistant K. pneumoniae mutants exhibited a dramatic decrease in hypermucoviscosity associated with reduced capsular polysaccharide production, resulting in defects in virulence . Reduced virulence with respect to serum susceptibility and survivability of G. mellonella has previously been reported in tigecycline-resistant Acinetobacter baumannii . However, it is not yet known how the development of tigecycline resistance affects virulence in bacteria. In this study, we investigated which changes that occur during the development of tigecycline resistance in K. pneumoniae lower the virulence. Transcriptomic analyses have confirmed that some genes that may be associated with tigecycline resistance are expressed differentially in two tigecycline-resistant mutants, for example, ramA . We detected decreased expression of a porin, OmpK35, in both tigecycline-resistant mutants. In K. pneumoniae, OmpK35 is a homolog of the E. coli OmpF porin . It is responsible for rapid influx of β-lactams including third generation cephalosporins and carbapenems in K. pneumoniae clinical isolates [20, 21]. Thus, a deficiency or a defect in the porin results in resistance to cephalosporins and carbapenems. Recently, decreased expression of OmpK35 was also identified in tigecycline-resistant K. pneumoniae strains . In addition to antibiotic resistance, decreased virulence has been reported in ompK35-deficient K. pneumoniae and ompF-deficient E. coli mutants [10, 22]. Since OmpK35 and OmpK36 are known to be regulated by a two-component regulatory system, OmpR-EnvZ-sensing osmotic signals [23, 24], we explored the effects of OmpR on the phenotypic changes that lead to virulence in the tigecycline-resistant mutants. First, we confirmed that tigecycline-resistant mutants overexpressed ompR and that ompK35 expression is regulated negatively by ompR. In addition, the expression of ompR increased with increasing concentrations of tigecycline. That is, OmpR might sensor the tigecycline, which may act as an osmolarity factor. Exposure to tigecycline produced a change in the phenotypes in hypervirulent K. pneumoniae strains. While tigecycline-susceptible and hypervirulent strains produced large, glossy, and mucoid colonies, the colonies of tigecycline-resistant mutants generated small, matt, and non-mucoid which may lead to the reduced virulence. Similar phenotypic changes were also observed in ompR-overexpressed mutants. In addition, after the deletion of ompR, tigecycline-resistant mutants were restored like phenotype of the tigecycline-susceptible K. pneumoniae strains. This implies that the overexpression of OmpR induced by tigecycline exposure can be responsible for the phenotypic changes in the hypervirulent K. pneumoniae stains. The phenotype changes in tigecycline-induced resistance and ompR overexpression were clearly associated with decreased virulence judged from the survival of NHS and G. mellonella larvae. The altered susceptibility to tigecycline caused by the overexpression or deletion of ompR may be associated with OmpK35 expression, which is regulated by OmpR. The smaller change caused by complementation with ompR may indicate that the influence of OmpR on the tigecycline susceptibility is indirect. Our study have some limitations. First, only a few strains were studied, limiting the generalization of the results. Second, it has not been revealed what features of tigecycline affect the expression of ompR and compK35. Nor have we found out why other antibiotics do not have these phenomena. CPS is known to be synthesized in different ways in K. pneumoniae K1 serotype, and thus would be further confirmed by various assays, for example, capsule stain and Periodic Acid Schiff stain. In addition, OmpK35 is a constituent of channel for extracellular polysaccharide (EPS) as well as CPS. As EPS may also be crucial for virulence, presence or amount of EPS should be compared between tigecycline-resistant and -susceptible strains. Based on the findings in this study, we speculated that the cause of the increased resistance to tigecycline and reduced virulence in hypermucoviscosity and hypervirulent K. pneumoniae strains attributed to the overexpression ramA by exposure to tigecycline [7, 12]. Tigecycline may simultaneously stimulate OmpR. Overexpressed OmpR binds ompK35, and acts as a repressor. Down-regulated OmpK35 caused by OmpR resulted in reduced virulence in hypermucoviscous and hypervirulent K. pneumoniae strains. In the present study, we demonstrated that ompR expression is regulated by exposure to tigecycline, thereby affecting the virulence associated phenotypes in K. pneumoniae strains. The reduced virulence in tigecycline-resistant mutants is probably an accompanying action of OmpK35, which is negatively regulated by OmpR. Availability of data and materials All materials are available by the corresponding author. Reads per kilobase per million Minimum inhibitory concentration Normal human serum Phosphate buffered saline Quantitative real-time PCR Wyres KL, Lam M, Holt KE. Population genomics of Klebsiella pneumoniae. Nat Rev Microbiol. 2020;18:344–59. Paczova MK, Mecsas J. Klebsiella pneumoniae: going on the offense with a strong defense. Microbiol Mol Biol Rev. 2016;80:629–61. Campos MA, Vargas MA, Regueiro V, Llompart CM, Albertí S, Bengoechea JA. Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides. Infect Immun. 2004;72:7107–14. Ko KS. The contribution of capsule polysaccharide genes to virulence of Klebsiella pneumoniae. Virulence. 2017;8:485–96. Yaghoubi S, Zekiy AO, Krutova M, Gholami M, Kouhsari E, Sholeh M, Ghafouri Z, Maleki F. Tigecycline antibacterial activity, clinical effectiveness, and mechanisms and epidemiology of resistance: narrative review. Eur J Clin Microbiol Infect Dis. 2021;2021(41):1–20. Jin X, Chen Q, Shen F, Jiang Y, Wu X, Hua X, Fu Y, Yu Y. Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin. Emerg Microbes Infect. 2021;10:1129–36. Goodarzi R, Arabestani M, Alikhani MY, Keramat F, Asghari B. Emergence of tigecycline-resistant Klebsiella pneumoniae ST11 clone in patients without exposure to tigecycline. J Infect Dev Ctries. 2021;15:1677–84. Pournaras S, Koumaki V, Spanakis N, Gennimata V. Current perspectives on tigecycline resistance in enterobacteriaceae: susceptibility testing issues and mechanisms of resistance. Int J Antimicrob Agents. 2016;48:11–8. Serek P, Lewandowski Ł, Dudek B, Pietkiewicz J, Jermakow K, Kapczyńska K, Krzyżewska E, Bednarz-Misa I. Klebsiella pneumoniae enolase-like membrane protein interacts with human plasminogen. Int J Med Microbiol. 2021;311: 151518. Tsai YK, Fung CP, Lin JC, Chen JH, Chang FY, Chen TL, Siu LK. Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence. Antimicrob Agents Chemother. 2011;55:1485–93. Matovina M, Abram M, Repac-Antić D, Kneževi S, Bubonja-Šonje M. An outbreak of ertapenem-resistant, carbapenemase-negative and porin-deficient ESBL-producing Klebsiella pneumoniae complex. Germs. 2021;11:199–210. Park S, Lee H, Shin D, Ko KS. Change of Hypermucoviscosity in the development of tigecycline resistance in hypervirulent Klebsiella pneumoniae sequence type 23 strains. Microorganisms. 2020;8:1562. Datsenko KA, Wanner BL. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Nat Acad Sci, USA. 2000;97:6640–5. Walker KA, Miner TA, Palacios M, Trzilova D, Frederick DR, Broberg CA, Sepúlveda VE, Quinn JD, Miller VL. A Klebsiella pneumoniae regulatory mutant has reduced capsule expression but retains hypermucoviscosity. MBio. 2019;10:e00089-e119. Insua JL, Llobet E, Moranta D, Pérez-Gutiérrez C, Tomás A, Garmendia J, Bengoechea JA. Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella. Infect Immun. 2013;81:3552–65. Seo SW, Gao Y, Kim D, Szubin R, Yang J, Cho BK, Palsson BO. Revealing genome-scale transcriptional regulatory landscape of OmpR highlights its expanded regulatory roles under osmotic stress in Escherichia coli K-12 MG1655. Sci Rep. 2017;7:2181. Zhang J, Xie J, Li H, Wang Z, Yin Y, Wang S, Chen H, Wang Q, Wang H. Genomic and phenotypic evolution of tigecycline-resistant Acinetobacter baumannii in critically ill patients. Microbiol Spectr. 2022;10: e0159321. Wang X, Chen H, Zhang Y, Wang Q, Zhao C, Li H, He W, Zhang F, Wang Z, Li S, Wang H. Genetic characterisation of clinical Klebsiella pneumoniae isolates with reduced susceptibility to tigecycline: role of the global regulator RamA and its local repressor RamR. Int J Antimicrob Agents. 2015;45:635–40. Doménech-Sánchez A, Martínez-Martínez L, Hernández-Allés S, del Carmen CM, Pascual A, Tomás JM, Albertí S, Benedí VJ. Role of Klebsiella pneumoniae OmpK35 porin in antimicrobial resistance. Antimicrob Agents Chemother. 2003;47:3332–5. Jacoby GA, Mills DM, Chow N. Role of beta-lactamases and porins in resistance to ertapenem and other beta-lactams in Klebsiella pneumoniae. Antimicrob Agents Chemother. 2004;48:3203–6. Sugawara E, Kojima S, Nikaido H. Klebsiella pneumoniae major porins OmpK35 and OmpK36 allow more efficient diffusion of β-lactams than their Escherichia coli homologs OmpF and OmpC. J Bacteriol. 2016;198:3200–8. Hejair HMA, Zhu Y, Ma J, Zhang Y, Pan Z, Zhang W, Yao H. Functional role of ompF and ompC porins in pathogenesis of avian pathogenic Escherichia coli. Microb Pathog. 2017;107:29–37. Walthers D, Go A, Kenney LJ. Regulation of porin gene expression by the two‐component regulatory system EnvZ/OmpR. In the Bacterial and Eukaryotic Porins: Structure, Function, Mechanism. 2004;1–24. Wang M, Tian Y, Xu L, Zhang F, Lu H, Li M, Li B. High osmotic stress increases OmpK36 expression through the regulation of KbvR to decrease the antimicrobial resistance of Klebsiella pneumoniae. Microbiol Spectr. 2022;10:e00507-e522. Soncini FC, Véscovi EG, Groisman EA. Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon. J Bacteriol. 1995;177:4364–71. Donnenberg MS, Kaper JB. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect Immun. 1991;59:4310–7. Lee JY, Chung ES, Na IY, Kim H, Shin D, Ko KS. Development of colistin resistance in pmrA-, phoP-, parR-and cprR-inactivated mutants of Pseudomonas aeruginosa. J Antimicrob Chemother. 2014;69:2966–71. Tigecycline was provided by Pfizer. This research was supported in part by the Basic Science Research Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) (NRF-2022R1A2B502001716). Ethics approval and consent to participate Consent for publication The authors declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. About this article Cite this article Park, S., Kim, H. & Ko, K.S. Reduced virulence in tigecycline-resistant Klebsiella pneumoniae caused by overexpression of ompR and down-regulation of ompK35. J Biomed Sci 30, 22 (2023). https://doi.org/10.1186/s12929-023-00910-w - Klebsiella pneumoniae
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I often forget that we get to choose how we react to things. Last Valentine’s Day when I was going to the bakery I got stuck in our car elevator (I know, it is weird to have a car elevator) and freaked out on the phone with Andrew. The poor guy was on a plane about to take off and although he asked the flight attendant to let him off, they’d taxied out to the runway and were not about to do that. Good thing too because after about 45 minutes the elevator rattled into action and I did not perish. The chance of perishing in a ventilated car elevator in a big city is slim to nil, and even if it wasn’t, losing my cool with Andrew wouldn’t have helped. Anyway, this week I have been thinking about how I react to things after two situations that were arguably more daunting than the car elevator incident but in which I kept my cool. The first situation was a fortified-cupcake sales/exploratory meeting with a dietitian. Earlier in the week we had a super meeting in which we even got an order for a trial run (!) but in the meeting yesterday, nothing was right about our product. Icing, paper liner, cost, size…all wrong. “Not at this time” was the answer to the question whether there would be any place for it in their menus and if you’d been there you would agree that this meant,”No, and never ever”. The second situation was a phone call to a bakery owner in the GTA who has a nut free bakery. As part of our fortified cupcake/manufacturing project, we want to convert the Yorkville store to nut free and figuring out just the supply chain is proving to be really hard. So I was calling this bakery an hour from Toronto to see if she would have any thoughts on the nut free supply maze. “I consider you competition and I don’t choose to help you”, she said, in a tone that implied I had just robbed her store. Weirdly, I felt completely calm and even serene in both of these situations, so much so that I found myself thinking, “Why aren’t I upset or hurt?”. Eventually I realized that after long enough on a difficult project, you get immune to problems, rejection, people who are less than helpful – and this is actually a very good thing! And when something good happens – like when we had really NAILED the product or the Monday morning meeting, wow!! There is this euphoria that is really quite out of touch with reality. So don’t give up. Things may not get any better for a very long time but eventually it is going to be easier to take 🙂
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For your convenience, all sessions will take place online via video. I will provide a HIPAA-compliant video link; you will need good wifi access, a private space, and a computer or phone with a camera and video capabilities. To schedule a session or request more information, please call or email. I’m happy to address any questions or concerns you may have. Phone: (612) 524-8008 Fax: (612) 886-1920 Make an Appointment
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Launching a website doesn’t have to hurt. Instead of banging your head against the wall, let me take care of it for you! Here’s what Rosebud Designs can do for you: All manner of WordPress jobs are tackled here, from the “just the facts, ma’am” templating jobs to full-featured sites that go from concept to design to development to deployment. Here’s the menu: - Building a custom template from a Photoshop or Illustrator file - Simple WordPress blog design (if you’re not using it for your whole site) and integration into an existing site - Tweaking of currently existing templates - Converting an already existing site to the WordPress platform - Building a full content management system - Installation of plugins and other modules within the WordPress framework (such as adding photo galleries, calendars, membership-only pages, e-commerce, etc.) - Getting other third-party ready-made scripts, such as bulletin boards, forums and e-commerce programs to hold hands and play nice with WordPress If you’re also not sure about hosting, or how to install WordPress, those needs can be taken care of too. All clients who get a site built in WordPress get a manual on how to use their site at the very end, and you can schedule some phone time or in-person time (if you’re in the Los Angeles area) for a live demo. Web design / development WordPress isn’t the only language spoken here! Many of your other web needs can be handled here, including: - Membership sites - Good ol’ fashioned HTML and CSS - CSS troubleshooting - E-newsletter design and templating (and helping you choose a newsletter provider too!) Consulting For Fellow Creatives Rosebud Designs has always been open to collaboration. If you’ve never tackled an e-commerce project an need some guidance, or you want to see if a WordPress solution will work for your project, or even if you have no idea why your stylesheet isn’t working in Internet Explorer, drop a line. Rosebud Designs works with a team of eager, creative folks ready to make you a star. Training / Teaching Teaching is in my blood! If you or your group needs training in Photoshop, Illustrator, InDesign or Dreamweaver, or you’d like a crash course in WordPress, please let me know. I’ve done small seminars for faculty at local colleges, workshops for high school students and one-on-one training.
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Over the last few days Harambe, the majestic gorilla from the Cincinnati Zoo, has dominated the news cycle. A beautiful animal in the prime of its life was sadly, but necessarily shot dead to save the life of a three year old child that had wandered into the gorilla’s enclosure. The consensus is that the gorilla had every right to live and it is a tragedy that he is dead. But the story of Harambe has made me think, what about animals that want to die? Progressives in this country are always pushing animal rights and right to die laws for human beings, but who will speak up for animals that want to end their own lives? I have to decided to take on this sure to be controversial idea to help my dog Cookie, who clearly wants to die, but is forced to continue living by a society obsessed with “doing the right thing” for dogs. Cookie is a mixed breed dog about 1.5 years old and she just wants to end her life. According to the journal Science, dogs think about suicide 48 times a day and try to end their lives at least once per week, whether it’s chewing down on toys until they become choking hazards or running into traffic or “curiously approaching” dangerous animals. We have all added our own human spin on these behaviors, but they sometimes point to a clear desire to die. That is where Cookie’s story begins. Cookie was found abandoned in a Kentucky trailer park, presumably giving up hope for the coal industry’s comeback that Donald Trump is promising. She was malnourished and full of mange. She was sent to a shelter with a high kill rate, but unfortunately for Cookie, her various breeds of dogs, none of which were Labrador or Golden Retriever made her look like a mixed breed golden lab puppy. So instead of being able to leave this cruel world her “golden privilege” led her to be saved by a Golden Retriever rescue organization. Less than 2 months later she was sent on a 14 hour van ride to NYC, which she has morbidly referred to as “The Middle Passage,” for her new life with me. While in New York the hints came quickly and often. Constant urination in my apartment. She might as well have been Arnold Schwarzenegger in Predator screaming “Kill Me!!!! Do it!!!! I’m heeeyaaaaaagghh!” But instead I selfishly sought advice on how to condition her behavior and the urination basically stopped. I began to take Cookie to the local dog park. At first she humored me by playing with other dogs and running around for exercise. She even developed some solid muscle tone, but eventually she began to get bullied by other dogs and would often just retreat into a corner with a scared look on her face. Most people just “awwww”ed at her, but i started to realize what she was actually saying to me: “Please Kill Me.” I didn’t want to believe at first, but then her messages became clearer. Her Thunder Jacket did nothing. Her face during bath time said “drown me” and all she would do was lie around all day, every day, often ignoring her toys. Then there was the day I caught her trying to choke herself to death by chewing on a tennis ball. I felt like Clint Eastwood in Million Dollar Baby at this point. Then I woke up earlier this week and realized, what is more progressive and respectful of the wishes of an animal than to respect its wish to end its life respectfully? The messages have been clear and it would be selfish and cruel of me not to respect them. Just this morning I saw her chewing her own paw, and she often chases her own tail, as if to say, “If these humans won’t do it I will have to hunt myself down.” I am done fighting to preserve society’s old fashioned rules of who gets to decide when a dog should live or die. I stand up today for Cookie’s right to end it all. No more NYC traffic. No more cruel dogs at the dog park. No more treats and toys as opiates for the pain of a life not worth living anymore. As tragic as the death of Harambe was, I think the only thing worse would be letting an animal live that clearly wants to die. Donations for Cookie’s memorial service can be sent to email@example.com on paypal. Seeking to raise $10,000 to both honor her struggle and raise awareness for other animals who want to die with dignity. #DignifiedDeathForCookie on Twitter
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Videos Become Yacht Brokers’ Go-To Promotion Method Please subscribe to the JMYS YouTube Channel Let’s face it, most of us would probably rather see the movie than read the book. The proliferation of videos on the internet, kicked off with the wild popularity of YouTube, but also from gaining traction on Vimeo and other portals has made it easy for anyone with a palm sized camera to shoot some footage and post it for the world to see. We are entranced by screens and they are inescapable – small screens on our smart phones, tablets, computers, in our cars and on our boats, larger viewing screens on our home televisions and the delight of enjoying the latest Hollywood release on the big screen in the theatre. In the trawler world we are starting to see more and more brokers use this form of promotion (trawler videos) to attract attention to their listings. Jeff learned about the powerful reach of YouTube through four videos which he filmed while with Nordhavn. In the first three years after release, these three videos had a combined total of 160,000+ views and more people continue to discover and enjoy them every day. That seemed like a big deal over six years ago. Now all three Motorsailer videos, dated as they are (and like anything filmed, stuck in time) showcase a product that is no longer built, yet they have continued to grow in views. JMYS has been publishing our “Talk Through Tour” style of videos since May of 2014. Jeff is enthusiastic, knowledgeable about his business and a natural presenter. We are astonished at the amount of views and the huge number of thumbs up people leave, all very encouraging. What started out as a side, a fun “new” way to share information, has blossomed into a staple, often imitated now by others jumping on the bandwagon. Folks interested in trawlers regularly get in touch with our team and for many, seeing a JMYS video on YouTube was their introduction to our approach. Our team is eager to help, happy to share, ready to listen. Our business is connecting with people.
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● At least ● Java/Frameworks: Java, Spring Boot, Spring Web/MVC, Spring Security, Spring Cloud, Spring Data, Spring Session, Artemis, Hibernate, QueryDSL, Camel, Logstash, Liquibase, Maven; ● Servlet containers: Tomcat; ● SSO: OAuth, SAML, JWT; ● Backend: MS SQL Server (2008+), MySQL, ElasticSearch, Microstrategy; Architecture: distributed architecture, SOA, microservices, JMS, REST API; ● CI: Jenkins/Jenkins pipelines; ● Bug Tracking and Project Management: Jira; ● Source Control: GIT; ● English — Intermediate level or higher. ● Experience with ElasticSearch/Redis/Kubernetes ● Work in a team of smart and talented people; ● Be a part of a fast-growing product company; ● Comfortable office in the city center or remote type of work (you can combine); ● Holidays per Ukrainian calendar; ● Flexible work schedule within Ukrainian business hours and a friendly atmosphere in the office; ● Free English classes. Create & support user information solutions by developing, implementing, and maintaining Java based components and interfaces. VisiQuate is a daily SaaS-based service for healthcare and enterprise clients that makes the volume, variety, and velocity of Big Data simple and actionable. VisiQuate has data scientists, visual scientists and subject matter experts who integrate Terabytes of incompatible Big Data onto a single platform. We are using the cutting edge technologies in order to deliver the best SaaS BI platform. Several applications: BI engine, Workflow engine, Predictive, VisiQuate custom UI suite. Platform architecture is microservice-based and provides RESTful API for all applications integration. All applications communicate through internal message addresses (Artemis) and services. We use Spring framework and the latest and greatest application design patterns to build VisiQuate BI platform. We work with traditional (SQL Server, mySQL) DBMSs and latest data processing (Elastics Search, Hadoop). Sonata Integration Studio: custom build Data Integration Orchestration studio based on Camel integration framework for real-time and batch data. All our applications are running inside containers on Kubernetes and support automatic deployments and auto-scaling.
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Lindsay Corporation is a provider of range of water management and road infrastructure products and services. The Company operates in two segments: Irrigation and Infrastructure. The Company’s irrigation segment includes the manufacture and marketing of center pivot, lateral move, and hose reel irrigation systems, which are used principally in the agricultural industry. The Company’s infrastructure segment includes the manufacture and marketing of moveable barriers, specialty barriers, crash cushions and end terminals, road marking and road safety equipment, large diameter steel tubing, railroad signals and structures, and outsourced manufacturing services. In August 2013, the Company announced that it has completed the acquisition of Claude Laval Corp.Something looks off?
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Below is my column in the Hill Newspaper on third round of litigation over the immigration orders issued by President Donald Trump. On Friday, in Honolulu, U.S. District Judge Derrick Watson converted the earlier temporary restraining order into a preliminary injunction. With the two decisions in Hawaii and Maryland, the appeals should move on an expedited basis back to the Supreme Court (which is expected to dismiss the second immigration case from the second round of litigation this week). Like T3, EO3 could be named “Redemption” as the Administration gears up for what is likely (and hopefully) the final round in this series. Here is the column: The new round of court opinions this week blocked parts of President Trump’s latest immigration executive order, known as travel ban 3.0. This litigation confirms everything that most of us hate about sequels that replay earlier plots and repeat material. Each new sequel tends to get more implausible with time with the appearance of previously killed villains (think “Terminator”), new “celestial” fathers (think “Guardians”), or previously destroyed evil organizations (think “Avengers”). The travel ban 3.0 litigation is, to quote the much sequeled Dr. Evil, “all of that and a bag of chips.” Judges in Maryland and Hawaii have enjoined a Trump travel order for the third time, replaying the same arguments as the earlier opinions, despite a new set of facts and language. Worst yet, we never actually got to a final battle royale in these cases in travel ban 1.0 and travel ban 2.0. Like the “Avenger” movies, we got to the long-awaited climax before the Supreme Court, only to have the court dismiss the case as moot. We were left with one of those teasers after the credits of a new threat looming in the future. Welcome to travel ban 3.0, much like T3 but without the aging cyborg. Both injunctions will trigger another nail biting, cliff hanging series of appellate decisions. However, in reading these opinions, you will likely feel like you have seen this one before. This series began on Jan. 27 with the first executive order. The poor drafting of that order was only matched by the even worse execution and defense of the order. Various judges found the order as motivated by an anti-Muslim “animus” and replayed Trump’s most incendiary comments from the campaign about a “Muslim ban.” Travel ban 1.0 was soon replaced by travel ban 2.0 on March 6, which was itself enjoined pending a final decision before the Supreme Court. The Supreme Court then reversed the lower courts on their injunctions except for protections for immigrants with “bona fide relationships” in the United States. However, shortly before oral argument, the court mooted one of the two cases after travel ban 2.0 died of natural causes with the expiration of its proscribed 90-day period. (The remaining case is likely to be dismissed when the rest of the second order expires.) The new order issued Sept. 24 contains a new list of countries that dropped some of the original countries while adding new non-Muslim countries. For the record, I have long criticized the earlier orders against the travel orders as relying too heavily on campaign statements and too little on existence case law. I believe that the administration would have largely prevailed on the second order if the litigation were not mooted. The new opinions in Hawaii and Maryland offer basically the same narrative while ignoring the new factual foundation. While both judges are respected jurists and reached good-faith conclusions, the opinions work too hard to ignore material changes that undermine the earlier holdings on religious and nationality discrimination. In Hawaii, District Court Judge Derrick Watson begins with a curious sports analogy that “professional athletes mirror the federal government in this respect: They operate within a set of rules, and when one among them forsakes those rules in favor of his own, problems ensue. And so it goes with [the third executive order].” From the perspective of the White House, of course, Watson himself could be viewed as violating those rules in acting like an active player rather than a referee in the game. Watson sees the executive order as still discriminating on the basis of nationality. Yet, it is impossible to specify inadequate entry procedures without designating the responsible and high risk countries. If that is discrimination based on nationality, most procedural rules addressing the failures of individual countries would seem to fail under the test, including orders from past presidents. In Maryland, District Court Judge Theodore Chuang notably only enjoined the order as to the Muslim countries and only as to individuals without “a bona fide relationship with an individual or entity in the United States.” As such, the court actually allowed much of the order to be executed. Yet, Chuang held that travel ban 3.0 failed to “cure” the “religious animus” behind the earlier travel ban. Chuang seems to place a heavy burden on the administration to “prove the negative,” or, in this case “prove you are not anti-Muslim.” Chuang admits that Trump has made “positive” statements about Muslims, but he simply rejects those statements in favor of Trump’s more inflammatory statements. He noted, for example, Trump’s tweet where he praised a discredited story about shooting Muslims with bullets dipped in pig’s blood as a deterrent to Islamic extremism. There is no question that President Trump continues to make the defense of these orders more difficult with his controversial tweets. However, the materiality of these statements has become more and more forced with each new generation of agency findings. Agencies studied the vetting procedures for months and reached a consensus on the changes that they deemed necessary for border protection. Such factual findings are normally accorded deference by courts, which are bound not to substitute their judgment for policy or political choices. Chuang notably found that the administration may have met the “low bar” of establishing that entry from these countries would be “detrimental to the interests of the United States.” However, he insisted that the administration did not “explain why the broad travel ban is necessary in a way…unrelated to religious animus.” It is not clear how the administration is supposed to prove that, particularly after shouldering the burden on the detrimental impact to the nation’s security. The administration cited “inadequate identity management protocols, information sharing practices, and risk factors,” including need technological improvements. While the plot and development may seem painfully familiar, viewers can only hope that cases will actually reach a final culmination. It is a moment reminiscent of John Connor’s frustration in T3 when he told the terminator, “No, you shouldn’t exist…We stopped judgment day.” The response of T3 could easily have come from travel ban 3.0: “You only postponed it. Judgment day is inevitable.” So stay tuned.
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January 11, 2022 What a handsome young man – and I can say that because this guy is family! I can’t believe little Iz is already a senior! Iz is the son of one of my cousins and I was so excited to do his senior session at Champoeg Park. It’s such a gorgeous background for photos no matter the time of year really. It’s so versatile too with a few different background options. There’s the beautiful wooden oak grove, which is where we started out. Iz was such a natural! We then made our way through the pathway to another section of the park. This area has a rustic wooden fence alongside a wide open tall grassy field. Perfect spot for an outfit change to give a different look. Iz totally killed it during his session at Champoeg Park! He was pulling off some serious model vibes! His momma, who is my cousin, teared up during his session at how quickly he’s grown. Our kids have gotten so big so fast it’s hard to wrap our heads around this incredible time they’ve worked so hard to reach. And we couldn’t be prouder of them! Pretty soon, my oldest won’t be far behind! Congratulations Iz! I wish you so much luck and blessings for your future. Love senior sessions? Take a look at Brenna’s musical senior session in Salem! https://joniloraine.me/2021/08/13/a-musical-senior-session-in-salem/
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Can You Take Airborne With Diabetes ? - 1.Does Pomegranate Juice Raise Blood Sugar - 2.Does Coke Zero Raise Blood Sugar - 3.Flax Seeds Lower Blood Sugar - 4.189 Blood Sugar After Eating - 5.Libra Blood Sugar Meter is tamarind good for type 2 diabetes Blood Sugar Chart, Normal Blood Sugar Levels can a cmp detect diabetes What Is Type 2 Diabetes. yuhao chuckled, his speed increased suddenly, and he turned into. Integrated, which is the real development trend best food for gestational diabetes in the future although we have ignored soul guides for a long time, the sun moon empire is exactly the opposite of us they rely too much on. Consciousness in your soul will gradually transform into divine consciousness it will increase as your cultivation level improves however, I must remind you that you must not release your. A strong sense of panic began to fill his heart he found tang wutong with great difficulty, but his soul left his body strangely what happened no, I don t want to leave, I don t want to. Haodong s power has also undergone some changes in her original golden soul power, there is an extra layer of blue purple huo yuhao has seen this blue purple layer before at the. Shown by yan shaozhe before, I am afraid that he must be at least at the contra level to practice such skills now it s just right to start by yourself huo yuhao was not the only one who. Them to carry out martial soul fusion purely for the cultivation of soul power, it has already reached a level close to that of a ninety two level title douluo of course, because none of. Unless it is dog diabetes treatment a high level beast like the dragon race but even for the dragon race, their intelligence is tamarind good for type 2 diabetes needs to grow for a certain period of time before they can be fully opened it is. Was startled, and couldn t help but take a few steps back what are you doing huo yuhao laughed and said, have you heard the story of the big bad wolf and the little white rabbit the big. My room to practice tonight you also know that I am still a soul master, so I can t let this practice go after eating, huo yuhao approached xuan ziwen obsequiously looking at huo yuhao. Farther away from his body although the induction was still there, he couldn t control his soul soaring into the sky this is why what happened to me huo yuhao couldn t find an answer, and. To come alive, hovering in the clouds like nine green dragons, the plate was still turning slowly, and the nine green dragons were floating on the clouds, they seemed to be playing and. 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Not as big as the carving knife he usually used to make soul guides huo yuhao continued to watch with doubts a hundred digit chapter is presented, everyone guess, who is this person do. Subconsciously walking into the valley, a stone paved path appeared at his feet, extending into the valley, with various plants growing on both sides of the path with huo yuhao s vision. The best disciples only then can you feel the power of heaven and earth contained in the golden tree at the right does metformin cause diabetes time, so as to find your own way both huo yuhao and tang wutong had. Side of the research room however, huo yuhao s complexion became ugly again after carefully looking at the blueprints for making the shell with his ability, make a soul guide shell even. Junior brother, how can you sleep even if you are sleeping, be alert, don t get caught xuan ziwen glared fiercely at huo yuhao, then turned his head to look around his movements were very. 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What Causes Diabetes is tamarind good for type 2 diabetes Josie Girl Blog can a cmp detect diabetes Fasting Blood Sugar. as tang wutong in the depths of huo yuhao s eyes, there was a purple color in the. Very much fortunately, his ultimate ice was highly resistant to high temperatures, and he was not burned under the action of the ice emperor s claw the biggest problem in making the shell. Bad wolf will not let you go today tang wutong laughed immediately, rabbits is tamarind good for type 2 diabetes What Is A Dangerous Level Of Blood Sugar will bite people when they are in a hurry huo yuhao s smile became even more rippling, bite, go ahead, brother. Cultivation was still a bit longer, but in tang wutong s perception, she seemed to have just slept in the love surrounding huo yuhao I m sorry elder xuan, we re leaving now huo yuhao. Advantages, but it also has a disadvantage, which is loneliness gods who can truly stay in the god realm are able Blood Sugar Chart can a cmp detect diabetes to endure loneliness in the god realm, you can have everything you want. Dancing in front of his eyes xuan ziwen s face was obviously a little ugly, you made this shell huo yuhao nodded and said, yes xuan ziwen said where is the rest of the red demon gold i. You leave is tamarind good for type 2 diabetes here otherwise, you will stay in the laboratory for eating, drinking, and sleeping don t even think about going out the torture last night, coupled with xuan ziwen s strength. Suddenly appearing in the dark, pulling his soul and rushing out of the sea god pavilion in an instant, and it actually came out of the tree house of the golden tree and rose into the air. Wutong on tang wutong s forehead, the light of the golden trident rune flickered slightly, and the blue purple halo in it flowed and merged into her body continuously the difference from. Turned his head and looked at huo yuhao who had already been stunned with a smile this is tamarind good for type 2 diabetes is the first dish of Blood Sugar Chart can a cmp detect diabetes the day, unfortunately, you can t eat it it was only then that huo yuhao woke. The other twelve, and then assemble the alchemy furnace for can you get ssi for type 1 diabetes me after all these are done, I will give you a day off if it wasn t for the fact that he couldn t . can a cmp detect diabetes High Blood Sugar How To Prevent Diabetes is tamarind good for type 2 diabetes Josie Girl Blog. bear the blood in his. Three soul engineer groups is basically complete now, so you can help me out what the younger brother said at the beginning was right the power of soul masters and soul guides are fully. Get it onto the experiment table the scorching temperature really made him feel very uncomfortable he has an ice attribute martial soul, so he doesn t like this kind of high temperature. And will be imprinted in your body and merge with you remember my words, whether it is cultivation or emotion, single mindedness is your greatest advantage go while speaking, the blond. But slender cracks quietly appeared in the air these rifts are closed soon after they appear to be continued the longyu jiwu saber technique is the top carving knife technique in my. Spiritual power, and each other s emotions were sublimating, even from the perspective of the sky, huo yuhao could clearly feel it what s going on why did my soul leave my body by itself. With hundreds of twists and turns ghost carving sword yes, it is is tamarind good for type 2 diabetes the ghost carving sword huo yuhao just remembered that the mysterious god of emotions once said that he wanted to give. Make people feel lonely I have many wives, and they are often not by my side no, there are only two who are willing to stay the others have gone out to play, and I don t know when they. Have changed just now at this moment, xuan ziwen jumped onto the experiment table in a flash the alchemy furnace was too big, and he couldn t see the whole picture just standing under it. Would leave such a seal on his daughter might not be so easy to deal with moreover, he also understands that the future father in law s strength may be quite powerful huo yuhao also asked. Pass on the top culinary skills you taught me back then and my understanding of culinary skills over the years the old man said in a low voice you played a bit too big this time this kid. Shell of the alchemy furnace and said, tell me, how did you manage to make the shell in just one day I don t believe it without the help of is tamarind good for type 2 diabetes external power huo yuhao sat down on the chair. Pulled tang wutong is tamarind good for type 2 diabetes up and quickly left the sea god pavilion when they came outside the sea god pavilion, they turned and looked at the golden tree isn t it in just a few days, the luster. This thing, huo yuhao has to admit that the value of this piece of red magic gold can even buy a small city, and it is absolutely priceless how many high level fire attributed soul guides. Break yuhao although he caitou s tone was pleading, it was also firm I won t hit him xuan ziwen said coldly really he caitou asked tentatively if you don t let me go, I ll drive you out. Soul tool by himself, he will definitely understand the absolute advantage of a soul tool over a soul master at that time, he is not afraid that he will not work hard if he is willing to. Really been chosen by god the lover returns, and the god appears everything seemed to be starting to become better this feeling of bitterness and reward immediately made huo yuhao s heart. Saber technique yesterday gave him great confidence that ghost carving sword is incomparably miraculous yesterday huo yuhao not only made the shell, but also conducted a series of. Young man waved his diabetes vomiting low blood sugar hand huo yuhao felt that everything around him had become unreal in the next moment, his soul body could no longer feel anything outside it was full of golden light. Is some human beings who have raised their own strength to be as pure as the elements of heaven and earth with the improvement of our strength, we can understand the dao of heaven and. Ice crystals, he carefully picked up the piece is tamarind good for type 2 diabetes of red magic gold, about half a cubic meter in size, and placed it on the soul tool experiment table although he is very reluctant to do. Attacks three times a day at the beginning, even the powerful attack of the evil eyed tyrant master could kill him, and he escaped with his fate however, this force that absorbs one s. While thinking, he has already arrived at he caitou s soul guide production room, and he caitou is now doing research on eight level soul guides with the guidance of xuan ziwen, a fellow.
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The association between variability, intensity, and persistence of suicidal ideation and prospective suicidal behavior in the systematic treatment enhancement program for bipolar disorder (STEP-BD) study International Journal of Bipolar Disorders volume 10, Article number: 17 (2022) This study sought to examine the association between prospective suicidal behavior and variability, intensity, and persistence of suicidal ideation (SI) in bipolar disorder (BD). Data were drawn from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), a naturalistic study of 4360 outpatients 15 years or older with BD. In separate models, logistic regressions with suicidal behavior (first attempt or death by suicide) as the outcome variable and SI variability (fluctuating levels of SI over time, measured as ordinal dispersion of SI score), intensity (median SI score over time in study), or persistence (number of visits with reported SI) as the explanatory variables were used to examine the relationship between SI characteristics and odds of future suicidal behavior events. After adjusting for possible confounders, the odds of prospective suicidal behavior were 1.2 times greater per 10% increase in SI variability. SI persistence was not associated with suicidal behavior. For SI intensity, a median SI score of ‘rare/fleeting’ or ‘several days’ of SI was not associated with suicidal behavior, but the odds of prospective suicidal behavior were nearly five times greater for participants with the highest observed median SI intensity score of ‘nearly every day’. The findings suggest that, in BD participants, monitoring SI variability may be clinically useful for assessing suicide risk. Suicidal behavior remains a significant public health burden. In the United States in 2019, over 47,000 individuals died by suicide, and over 312,000 emergency room visits for self-harm were reported (Centers for Disease Control 2021). Accurately assessing suicide risk is critical to mitigating these impacts, and it remains an essential part of current psychiatric practice. However, our ability to accurately predict suicidal behavior in a given individual remains poor, as does our understanding of the inherent mechanisms that lead to this complex, multifactorial behavior. Individuals with bipolar disorder (BD) are at significantly increased risk for suicidal behavior and represent one of many different psychiatric populations for which suicide risk assessment is especially pertinent (Schaffer et al. 2015). Disease-specific factors are known to influence suicidal behavior despite its transdiagnostic nature, and suicide models in BD have been developed to account for these possible differences. One such model, proposed by Malhi and colleagues, integrates findings gathered from multiple research modalities (ie, genetics and epigenetics, neuroimaging, and clinical research) to describe the suicidal process from ideation to behavior. A tenet of this and other models is the presence of risk factors that exist on a spectrum from proximal (ie, current anxiety) to distal (ie, family history) (Malhi et al. 2018). However, such risk factors may be difficult to detect, unreliably reported, or only indirectly observed. Few studies have investigated how the parameters of suicidal ideation (SI) itself—including the intensity (average level), duration (sustained levels over time), and variability (fluctuating levels over time) of SI—may predict suicidal behavior. In particular, research in community samples of children (Melhem et al. 2019) and college students (Witte et al. 2005, 2006) as well as in psychiatric populations with suicidal behavior (Bryan et al. 2019; Rizk et al. 2019; Wang et al. 2021) have suggested that SI variability is associated with suicidal behavior, even beyond the effects of SI intensity or SI duration (Rizk et al. 2019). Such fluctuations in SI may be perplexing to clinicians, particularly in patients who have persistent fluctuations in SI but no history of past suicidal behavior, and may even lead them to discount the risk of future suicidal behavior. Thus, it is crucial to investigate patterns of variability in SI and how these patterns may relate to the risk of prospective suicidal behavior. Studies have suggested that different suicidal subgroups (i.e., those with trait-like high and low SI variability) may be associated with different risk factors and clinical characteristics (Bryan et al. 2019; Oquendo et al. 2020). One such study of females with borderline personality disorder and history of suicide attempt concluded that SI variability may be explained by affective instability—broadly defined as fluctuating changes in mood over time—after adjusting for severity of depressive symptoms (Rizk et al. 2019). Historically, much of the research to elucidate the processes and risk factors associated with suicidal behavior has been conducted in psychiatric subpopulations characterized by specific diagnoses. The Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study (Sachs et al. 2003) is one such example. Previous research from this naturalistic study of over 4000 individuals with BD described long-term and acute risk factors for suicidal behavior (Antypa et al. 2013; Ballard et al. 2016, 2020; Dennehy et al. 2011; Simon et al. 2007; Stange et al. 2016a, b). The present study used data from the STEP-BD study to investigate the association between suicidal behavior and SI variability, SI intensity, and SI persistence (defined as consistent reporting of SI in the months leading up to a suicidal behavior event) in participants with BD; SI persistence was used because many study participants exhibited suicidal behavior in the months after study entry, and duration could not be directly evaluated. Our study also sought to examine whether the relationship between SI variability and prospective suicidal behavior differed by degree of affective instability. Study hypotheses included: (1) that each of the SI characteristics would be positively associated with suicidal behavior; and (2) that affective instability would modify the relationship between SI variability and suicidal behavior. All data for this exploratory analysis were drawn from the STEP-BD study; study characteristics have been described in detail elsewhere (Sachs et al. 2003). Briefly, the 7-year study followed 4360 outpatient participants, ages 15 years or older, with BD of every subtype. The study was conducted across 22 academic medical centers in the United States and was approved by the institutional review board of the participating institutions. All participants provided written informed consent. The primary study measure was the Clinical Monitoring Form (CMF) (see below). After excluding participants who had no CMF data, our initial dataset included 242 individuals who attempted suicide and eight who died by suicide. Two transgender individuals, both of whom were in the group exhibiting no suicidal behavior, were removed from the analysis due to small sample size. The data were restricted to only include individuals who completed at least three study assessments and who remained in the study for more than 60 days (113 individuals with a suicidal behavior event (SB group) and 3081 individuals without an event (No SB group). The data were further restricted to include only individuals who reported any SI during the study period (which varied by participant). This final dataset comprised 92 participants (64.1% female) in the SB group and 1863 participants (58.9% female) in the No SB group. Data on suicidal behavior, defined as either a suicide attempt or a death by suicide, were collected from the Severe Adverse Events (SAE) and Care Utilization (CU) forms as previously described (Ballard et al. 2020). The CMF, which was the primary outcome measure in the STEP-BD study, was used to evaluate participants at each outpatient visit with their treating psychiatrist. The CMF measures the severity of DSM-IV mood symptoms (including SI) and other pertinent clinical characteristics within the prior 2-week period. The form has been well-validated and correlates strongly with other mood rating scales such as the Hamilton Depression Rating Scale and the Montgomery-Åsberg Depression Rating Scale (Sachs et al. 2002). Data from the CMF were merged with data from the Affective Disorder Examination (ADE), a semi-structured interview conducted at study entry, which contained the same clinician-administered rating scales found on the CMF. Additionally, information on substance use was drawn from the MINI International Neuropsychiatric Interview (MINI), a brief structured interview for the major Axis I psychiatric disorders also conducted at study entry. Additional details about these forms can be found in the Additional file 1: Methods. Three explanatory variables were used to examine the relationship between SI characteristics and odds of a future suicidal behavior event: SI variability, SI intensity, and SI persistence. All three were derived from the SI scale of the CMF. Given the ordinal quality of the scale, a statistic for ordinal dispersion was used to assess SI variability over the study period (Blair and Lacy 2000). Briefly, the statistic defines an index of ordinal concentration by taking the sum of the squared difference of the cumulative relative frequency of each level of the scale and the state of maximal dispersion (which is equal to 0.5), and then normalizing by the value for maximal dispersion (given the number of levels of the scale). The difference of this number and one then provides a measure of dispersion of the ordinal variable on a scale from 0 (no dispersion) to 1 (maximal dispersion), where the produced values can be interpreted as the percent of the maximal possible dispersion for the given variable. This approach makes no continuous assumptions about the data and has been shown to produce little bias in estimates with large sample sizes, as is the case with our data (Blair and Lacy 2000). SI intensity was measured as the median SI score per participant over the study period, and SI persistence was measured as the proportion of visits with any reported SI out of the total number of visits over the study period for each participant. Using the ordinal dispersion statistic, measures of affective instability were derived from the DSM-IV mood symptom scales separately for mania and depression (excluding SI), in line with previous approaches (Stange et al. 2016a, b). Severity of depressive symptoms over the study period was measured by summing the absolute value of depressive symptom scores at each visit, again excluding SI, and then averaging these total scores over the study period. Because past studies have noted a relationship between Personality Disorders Questionnaire (PDQ) score and suicidal behavior in the STEP-BD study (Antypa et al. 2013), this measure was also included (see Additional file 1: Methods). Summary statistics were calculated for demographics and SI variability, SI intensity, and SI persistence for the SB and No SB groups. Logistic regression was used with suicidal behavior as the outcome variable, and each SI measure of interest (SI variability, SI intensity, or SI persistence) was used as the explanatory variable in separate models to examine the relationship between SI characteristics and likelihood of a future suicidal behavior event. Covariate selection was conducted to minimize the potential for spurious relationships between predictors of interest and outcome, and Pearson correlation coefficients were calculated with variables of interest and covariates to estimate potential sources of both confounding and collinearity. Based on literature supporting their relationship with either suicidal behavior, SI, or both, the following covariates were included in all models: age at study entry, gender, history of suicide attempt, PDQ score, severity of depressive symptoms, affective instability in depressive and manic symptoms, and alcohol or other substance abuse at study entry (Antypa et al. 2013). Number of total study visits was also included in the models for SI variability, SI intensity, and SI persistence to address possible confounding. To test the hypothesis that affective instability would modify the relationship between SI variability and suicidal behavior, each affective instability measure was interacted with SI variability. As a sensitivity analysis to protect against spurious relationships due to time in study, all of the models were run with only participants who exited the study within two years of study entry; results were similar (see Additional file 1: Table S1). Multiple imputation was used to account for missingness in the data, which included PDQ score (SB group: 29.8%; No SB group: 21.7%), history of suicide attempt (SB group: 3.2%; No SB group: 1.1%), alcohol abuse (SB group: 6.3%; No SB group: 7.6%), and substance abuse (SB group: 6.4%; No SB group: 7.6%). Regression results from both complete case analyses and multiple imputation analyses were found to be similar. Pooled multiple imputation results are reported below; see Additional file 1: Methods for additional information and Additional file 1: Table S2 for complete case results. All analyses were run using Stata version 16 (StataCorp, College Station, TX, USA). Of the 1955 participants included in the analysis, fewer than half were male (41.1% and 35.9% male for the No SB and SB groups, respectively), and most were white (92.0% and 90.2% in the No SB and SB groups, respectively). Mean age at study entry was 40.4 years (SD = 12.2) in the No SB group and 36.4 (SD = 11.6) in the SB group (see Table 1 for additional details). Participants demonstrated a relatively broad range of SI variability [No SB group: 2.87 ± 1.61 (range = 0–9.50); SB group: 3.63 ± 1.56 (range = 0.64–8.89)] as well as SI persistence [No SB group: 3.07 ± 2.34 (range = 0.17 to 10.00); SB group: 4.07 ± 2.55 (range = 0.42 to 10.00)]. SI intensity scores, as measured by median CMF SI score, were clustered near lower scores, suggesting the absence of SI (percent of individuals with median score of no SI: 79.5% in the No SB group and 64.1% in the SB group) (Table 1 and Fig. 1). Regarding model selection, number of study visits and time in study were not included in the same models because these variables were highly collinear (rs = 0.78) (Table 2) (see Additional file 1: Results for further details), and further adjusting for time in study did not substantially change the results after already adjusting for number of study visits. Affective instability did not modify the relationship between SI variability and prospective suicidal behavior (SI variability × depressive symptom instability: odds ratio (OR) = 0.73, p = 0.67, SI variability × manic symptom instability: OR = 1.19, p = 0.73). Consequently, these interaction terms were not included in the final model for SI variability. After adjusting for possible confounders, logistic regressions indicated that the odds of prospective suicidal behavior were 1.2 times greater per 10% increase in SI variability (OR = 1.21, p = 0.01). In contrast, SI persistence (OR = 1.10, p = 0.05) was not associated with suicidal behavior. For SI intensity, a median SI score of ‘rare/fleeting’ (OR = 1.54, p = 0.21) or ‘several days’ of SI (OR = 1.32, p = 0.45) was not associated with suicidal behavior compared with the reference group of no SI, but the odds of prospective suicidal behavior was nearly five times greater for participants with the highest observed median SI score of ‘nearly every day’ (OR = 4.81, p < 0.1) (Table 3). The findings did not fully support the first hypothesis that each SI characteristic would be positively associated with suicidal behavior. Rather, SI variability was found to be significantly associated with prospective suicidal behavior for BD participants, and SI persistence was not. In addition, only the highest level of SI intensity (corresponding to a median SI score of ‘nearly every day’) was associated with prospective suicidal behavior. The results also did not support the second hypothesis that affective instability would modify the relationship between SI variability and suicidal behavior. Taken together, these findings suggest that monitoring SI variability may be a useful clinical tool for assessing suicide risk. These findings are consistent with previous research suggesting that SI variability may explain prospective suicidal behavior (Wang et al. 2021; Witte et al. 2005). It should be noted that the relatively small magnitude of this result is not unexpected and in line with estimates of other risk factors, such as marital status, reported in previous research studies (Pescolido et al. 2020). Notably, the SI intensity level of ‘nearly every day’ was relatively rare in our suicidal sample (2.3%). High SI variability may indicate that a more in-depth suicide risk assessment is needed, especially among those without high SI intensity, which would appear to comprise most patients with SI. Interestingly, affective instability—broadly defined as fluctuating changes in mood over time—did not modify the relationship between SI variability and prospective suicidal behavior, suggesting that this relationship may occur independently of overall mood changes. Prior research on this topic has produced mixed results. While some studies reported an association between affective instability and history of suicidal behavior across a range of psychiatric populations (Palmier-Claus et al. 2012) as well as an association between severity of BD and history of suicidal behavior (Fagiolini et al. 2004; Oquendo et al. 2000), another study of BD participants found no evidence of a relationship between affective instability and history of suicidal behavior (Parmentier et al. 2012). One possible explanation is that there may be little association between affective instability and suicidal behavior after accounting for severity of depressive symptoms if individuals with higher affective instability spend less time in a state of severe mood symptoms, where risk of suicidal behavior may be highest. The absence of a finding of effect modification for affective instability may also be due to a number of study-specific reasons. First, the models used assessed effect modification on the multiplicative scale and not on the additive scale. Second, how researchers conceptualize and measure affective instability may differ between studies and study populations. Our finding contrasts with one observed in patients with borderline personality disorder (Rizk et al. 2019), but the constructs of affective instability may differ between these two populations (Reich et al. 2012) and were measured differently in the two studies. Third, it is possible that our separate measures of depressive and manic symptom instability did not capture the full spectrum or temporal nature of these dynamic symptoms. While our ability to capture this construct was in line with previous research efforts (Stange et al. 2016a, b), it was nevertheless limited by the information collected on the CMF; newer methods of data collection, such as ecological momentary assessment (EMA), may address these issues (Kleiman et al. 2017). Given that most suicidal behavior events took place early in a participant’s time course, this study could not assess the association between duration of SI and suicidal behavior. Instead, the measure of proportion of visits with reported SI primarily provides insight into the degree of SI persistence in the months leading up to a suicidal behavior event compared with those without an event. When restricting the analysis to participants who exited the study within the first 2 years of entry, an association remained between SI variability and suicidal behavior, but there was no clear evidence of an association between SI persistence and suicidal behavior. Strengths of the present study include the large sample size, the longitudinal nature of the data, and the standardized diagnosis, assessment, and treatment of the BD participants. The large sample size is particularly important given the lower incidence of suicidal behaviors. This analysis also expands on previous work in this area by: (1) extending research on SI variability to individuals with BD; (2) investigating the association between prospective suicidal behavior rather than history of suicide attempt or future SI; and (3) examining these relationships in a large, community-based sample. This analysis also has several limitations. First, because this was an exploratory analysis, it did not adjust for multiple testing, and statistically significant results should therefore be interpreted with caution. Second, the CMF was collected at outpatient follow-up visits and depended on both the clinician determination of need as well as participant behavior, which may have had a confounding effect on study results. For example, patients with lesser degrees of SI may not have been seen as frequently, or those with greater degrees of SI may have been more likely to be non-adherent to outpatient visits or more likely to be hospitalized, reducing their number of outpatient visits. The analysis attempted to partially account for these confounding effects by including the number of visits and time spent in the study into the models, and by restricting the analyses to the first two years from study entry; this approach, however, may not have fully accounted for these effects and, again, the results should be interpreted with caution. Third, while the study psychiatrists were trained on both the CMF and best practices for care of patients with BD, they may have behaved differently regarding the degree to which they adhered to the CMF interview and reporting form. Because the de-identified dataset does not include data at the provider level, the analysis could not account for these possible effects. Fourth, the STEP-BD study was conducted at academic medical centers where participants were responsible for covering the costs of their treatment; there was substantial drop-out over the course of the STEP-BD study and, consequently, the results may not be generalizable to other populations, such as patients seen in community clinics where participants may have been more severely ill or had different insurance coverage. Fifth, because SI severity—defined as maximum SI score—correlated highly with SI variability, it was not possible to distinguish between the effects of SI severity and SI variability in this dataset. Sixth, it is possible that participants in the No SB group went on to experience suicidal behavior after exiting the study, potentially limiting the generalizability of the findings. Finally, while the models showed good fit, using them to directly categorize risk of future suicidal behavior would be substantially limited because they did not predict the full range of values for predicted probability (about 0 to 0.6). This is likely due to the unbalanced nature of the data, given the overall low rates of suicidal behavior. Furthermore, using the models for prediction would require validation in additional datasets. SI variability may help explain risk of suicidal behavior as well as SI and could be considered in clinical contexts in addition to other routinely-assessed, common risk factors, particularly among individuals with lower SI intensity. 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Highly variable suicidal ideation: a phenotypic marker for stress induced suicide risk. Mol Psychiatry. 2020;26(9):5079–86. Palmier-Claus J, Taylor P, Varese F, Pratt D. Does unstable mood increase risk of suicide? Theory, research and practice. J Affect Disord. 2012;143:5–15. Parmentier C, Etain B, Yon L, Misson H, Mathieu F, Lajnef M, et al. Clinical and dimensional characteristics of euthymic bipolar patients with or without suicidal behavior. Eur Psychiatry. 2012;27:570–6. Pescolido BA, Lee B, Kafadar K. Cross-level sociodemographic homogeneity alters individual risk for completed suicide. Proc Natl Acad Sci USA. 2020;117:26170–5. Reich DB, Zanarini MC, Fitzmaurice G. Affective lability in bipolar disorder and borderline personality disorder. Compr Psychiatry. 2012;53:230–7. Rizk MM, Choo T-H, Galfalvy H, Biggs E, Brodsky BS, Oquendo MA, et al. Variability in suicidal ideation is associated with affective instability in suicide attempters with borderline personality disorder. 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Specific mood symptoms confer risk for subsequent suicidal ideation in bipolar disorder with and without suicide attempt history: multi-wave data from STEP-BD. Depress Anxiety. 2016a;33:464–72. Stange JP, Sylvia LG, Magalhaes PV, Miklowitz D, Otto MW, Frank E, et al. Affective instability and the course of bipolar depression: results from the STEP-BD randomised controlled trial of psychosocial treatment. Br J Psychiatry. 2016b;208:352–8. Wang SB, Coppersmith DDL, Kleiman EM, Bentley KH, Millner AJ, Fortgang R, et al. A pilot study using frequent inpatient assessments of suicideal thinking to predict short-term postdischarge suicidal behavior. JAMA Netw Open. 2021;4: e210591. Witte TK, Fitzpatrick KK, Joiner TEJ, Schmidt NB. Variability in suicidal ideation: a better predictor of suicide attempts than intensity or duration of ideation? J Affect Disord. 2005;88:131–6. Witte TK, Fitzpatrick KK, Warren KL, Schatschneider C, Schmidt NB. Naturalistic evaluation of suicidal ideation: variability and relation to attempt status. Behav Res Ther. 2006;44:1029–40. The authors thank the 7SE research unit and staff for their support. Ioline Henter (NIMH) provided invaluable editorial assistance. Open Access funding provided by the National Institutes of Health (NIH). Funding for this work was provided by the Intramural Research Program at the National Institute of Mental Health, National Institutes of Health (IRP-NIMH-NIH; ZIAMH002927). Ethics approval and consent to participate The STEP-BD study was conducted across 22 academic medical centers in the United States and was approved by the institutional review board of the participating institutions. All participants provided written informed consent. Consent for publication As part of the informed consent process, participants in the STEP-BD study provided consent for their anonymized data to be published. Dr. Zarate is listed as a co-inventor on a patent for the use of ketamine in major depression and suicidal ideation; as a co-inventor on a patent for the use of (2R,6R)-hydroxynorketamine, (S)-dehydronorketamine, and other stereoisomeric dehydroxylated and hydroxylated metabolites of (R,S)-ketamine metabolites in the treatment of depression and neuropathic pain; and as a co-inventor on a patent application for the use of (2R,6R)-hydroxynorketamine and (2S,6S)-hydroxynorketamine in the treatment of depression, anxiety, anhedonia, suicidal ideation, and post-traumatic stress disorders. He has assigned his patent rights to the U.S. government but will share a percentage of any royalties that may be received by the government. All other authors have no conflict of interest to disclose, financial or otherwise. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. About this article Cite this article Bloomfield-Clagett, B., Greenstein, D.K., Zarate, C.A. et al. The association between variability, intensity, and persistence of suicidal ideation and prospective suicidal behavior in the systematic treatment enhancement program for bipolar disorder (STEP-BD) study. Int J Bipolar Disord 10, 17 (2022). https://doi.org/10.1186/s40345-022-00263-7 - Suicidal ideation - Bipolar disorder - Affective instability
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Glitter Puzzles have arrived and we are pretty chuffed. Because Glitter makes everything better! The pictures do not do these beauties justice and they are very much ‘glitterier’ in real life. There is glitter in the puzzle pieces and the jigsaw puzzle box. Sparkle Jigsaw Puzzles are stunning and we can’t stop! We have 3 Sparkle Puzzles designs for you to choose from: For those who love Australian Indigenous Art Puzzles, we just had to add glitter to this stunning puzzle by Emma Stenhouse. Emma is a proud Australian Indigenous woman whose work we are thrilled to support. We have been wanting to create a puzzle out of Kate Jamieson’s work for the longest time. So we were thrilled when she agreed to let turn Gold Urn into a Sparkle Puzzle. “Ok, this one if my favourite. Probably one of my favourite Journey of Something puzzles ever.” Direct quote from Nicola, Journey of Something owner. How to seal a Glitter Puzzle We have been getting a lot of people asking if they can seal their glitter puzzle with Modge Podge Puzzle Saver or Modge Podge Gloss. The answer is yes, you can definitely seal your Glitter Jigsaw Puzzle. Both Modge Podge Puzzle Save and Modge Podge Gloss dry clear so they can be used on almost anything and you glitter will still sparkle through. How to frame a Glitter Puzzle There has never been puzzles more designed for framing then glitter puzzles. You frame them as you would any of our 1000 piece jigsaw puzzles. You can purchase a frame here – they are the correct size for Glitter Puzzles. Then follow these easy instructions on how to frame your Glitter Puzzle. Glitter Puzzle Gifting Made Easy For the absolute ultimate gift try our Glitter Puzzle lover bundle found here. It includes a Glitter Puzzle (or any 1000 piece puzzle of your choose), a perfect frame for your Glitter puzzle and Modge Podge Puzzle Saver Glue. Everything you need to create your own stunning home decor! Which is your favourite Sparkle Puzzle?
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I pulled out the WPlus9 set Encouraging Words and added a birthday sentiment from Strictly Sentiments 5. I love the scenes that can be built with the images in Encouraging Words. Tuesday, July 21, 2015 Happy Birthday Mountains! When I was thinking about a birthday card for a wonderful man, I quickly decided it needed mountains. He lived for years in my favorite all-time mountain town and they still go regularly for mini-vacations. I count his wife as a dear friend - we spent a wonderful afternoon not long ago wandering around that town and I realized that the family was an institution. Everybody knew her and she showed me hidden gems throughout the town. My foodie son counts one of the restaurants she pointed as his second favorite restaurant!! I created purple mountains, but I originally saw the set used with that stamp as a lake - check it out here. It's gorgeous either way. She also used one of the images that I used as trees as a misty mountain background. I so love flexible sets. Happy Birthday Ken!! Carol, we need to find time for coffee! FYI - I used different areas of the Ombre pad to get the different greens. I was hoping for a little more variation on the image - but it just doesn't show up well.
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ULTRA LOW PROFILE RIBBON TRACK Magnetic connection, surface mount. Create muted or show-stopping displays with our low-profile, two-circuit powered ribbon. We designed our snap-on technology for easy installation on any flat, hard surface. The connectors hug inside and outside corners seamlessly. Available in multiple high-quality finishes and colors. Custom colors are available upon request. Mount the powered ribbon on our suspended track in spaces with high or complex ceiling environments. Take advantage of the suspended track to mount an additional powered ribbon on the top surface of the track for indirect ambient light. If the ¼” ribbon is too tall, use our recessed track to create a completely flush surface. Contrasting ribbon and recessed track colors and finishes can yield visual effects unmatched by any other system. SURFACE MOUNTED CLIPS Our surface mounted clip system and quick snap-on ribbons allow for flexible installation. HIGH PERFORMANCE FINISHES Custom colors, satin white, satin black, satin aluminum, and primer white. Blend the track seamlessly into a design by painting it to match existing surfaces. An ever expanding collection of accessories and a series of pivot elements make for easy installation on nearly any flat surface and allow the system's segments to effortlessly change planes and navigate corners. Our tiny and mighty track heads are of unrivaled build quality. Each component is made from solid machined or cast aluminum parts. The base swivels 360 degress, and the arm rotates 90 degrees. The track heads can be manually repositioned anywhere on the ribbon at any time. Offering the same exceptional design and light quality as the spotlights, the monopoints are a highly functional fixture type of their own. They can be mounted with or without 5” cover plates for a truly minimal footprint that complements the architecture of any space. Multiverse is for more than just spot heads. It supports a growing library of directly mounted lighting fixtures, including our new collection of Multiverse cylinder pendants and almost any existing Juniper lighting fixture. Light up the system (literally) with our inline illuminated ribbon, which is the same height and width as the powered ribbon, resulting in a magical sequence of light and color that delivers functional ambient light. SUPERIOR LIGHT QUALITY 95+ CRI, 85 Lumens/Watt delivered average, and flicker free dimming. *Data shown for 500lm Spotlight Magnetic adapters can mount most JUNIPER products.
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Montana State plans Native Student Preview Day for Jan. 23 BOZEMAN – Montana State University will host high school and transfer students from all over Montana at Native Student Preview Day on Monday, Jan. 23. The event is designed to offer Native students a culturally relevant campus visit experience and provide in-depth information about what it’s like to attend MSU. Kristie Russette, outreach coordinator and recruitment specialist for MSU’s Native American Studies program, said MSU continues to increase resources for Native students as their enrollment grows. Organizers will showcase those resources, including American Indian Hall, which celebrated its grand opening in October 2021. The visitors will have a chance to meet MSU faculty and staff, engage with current students, tour the campus, meet with representatives of academic departments and learn more about other campus resources. All are invited to attend a lecture by astronaut John Herrington, the first Native American to have flown in outer space, on Monday afternoon. “We hope this will be an opportunity for students from other schools to meet our students and perhaps realize there are others out there like them who are interested in college,” Russette said. Interested students and groups can register online HERE. Registration is free and open to individuals, school groups and families. Scholarships are available to fund travel expenses for a small number of interested students. For more information, contact Russette at firstname.lastname@example.org or 406-994-3334. Native Student Preview Day is being co-hosted by American Indian/Alaska Native Student Success, GEAR UP at MSU, Office of Admissions, Empower Program, the Honors College and Montana Space Grant Consortium. It is sponsored by MSU’s offices of Diversity and Inclusion, the Dean of Students and the President; Department of Native American Studies; College of Agriculture, Empower Program and Montana Space Grant Consortium.
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Beautiful Bridesmaid Robes for Weddings, Bachelorette Parties & More Kadlee is proud to offer a gorgeous array of bridesmaids robes at a super affordable price. Paired with reasonably priced shipping options, you can give these robes as bridesmaids gifts for far less than you could if you purchased from another company. And when every penny of your wedding budget counts, it’s important to find thoughtful, attractive gifts that don’t cost a bundle. But affordability isn’t the only thing bridal robes from Kadlee offer. They’re also: If these aren’t enough reasons for you to order bridesmaids robes from Kadlee, know that our passion lies in making our customers happy. With years of experience in the events and wedding industry, we truly understand how special your wedding day is and how difficult it can be to find beautiful bridesmaid robes at a reasonable price. It’s our goal to make sure that our customers are able to get the bridal robes they desire at rock-bottom prices, whether they’re looking for floral robes, personalized robes, or a mix-and-match of colors. To learn more about ordering bridesmaid robes for your special day, contact Kadlee today! We ship our robes from Alpharetta, GA, to all areas nationwide and even internationally.
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Kampot Pepper holds the prestigious Protected Geographical Indication certification putting it on the same footing as other appellations of origin like Champagne, Cognac, Darjeeling Tea… We work with a collective of over 400 small farmers that are trying to rebuild their ancient farming system that was virtually destroyed during the Cambodian Genocide. A nearby sea, flanking mountains, a quartz-rich soil: It’s the perfect spot on earth, devotees say, to yield a product they describe in that rapturous vocabulary usually reserved for fine wines: “aristocratic, virile, almost aphrodisiacal,” with subtle notes of caramel, gingerbread and mild tobacco. (Denis D. Gray, The Associated Press) “The dogged determination to revive a once threatened crop is now starting to pay dividends. “It has a lot of cachet, something from the past,” says Bourdain. A full renaissance is a long way off: Cambodia exported only a few thousand kilograms last year. But awareness is growing fast, and as Laiskonis points out, Kampot pepper offers that all-important element of romance. “It has been rescued from time and events,” he says. “Ingredients that tell a story are a special thing you can offer people.” Chef Anthony Bourdain in Time Magazine Jan. 16, 2012 “It’s got a floral dimension that’s really something special…”
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Is it Spring Yet? Every late January, I find myself asking, “is it spring yet?” This shawl will make sure that I have my spring feels every day I wear it! Made in three sections with blocks of bold, spring colors, you cannot help but smile when you look at it. Worked from the top down in a simple half-circle construction, you will get to stretch your wings into lace and a fun edge. What color combination will you choose? You will receive the DIGITAL pattern only. 50 inches wide by 25 inches deep - 700 yards (595 m) DK weight yarn - US Size G/6 (4.0 mm) or size needed for gauge Sample uses Euro Yarns Baby Criative DK (40% alpaca / 30% cotton / 30% modal; 3.5 oz / 100g = 260 yds / 238m) in colors (A) #10 Aquamarine, (B) #03 Ice Queen and (C) #16 Groovy Grape
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Royal Blue Silk Kurti Regular price Rs. 999.00 Tax included. Shipping calculated at checkout. Gota laced royal blue silk straight kurti with three quarters sleeves WASHING INSTRUCTIONS: HAND WASH - There is a color mismatch of 10-12% as colors on your computer screen can differ from how they appear in person.
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