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Introduction {#sec1}
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Cutaneous leishmaniasis (CL) is the disease caused by *Leishmania* spp., an intracellular parasite. More than 70% of all CL cases are seen in 10 countries worldwide, which are Afghanistan, Algeria, Brazil, Colombia, Costa Rica, Ethiopia, the Islamic Republic of Iran, Peru, Sudan, and ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
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With the increasing affordability of personal genome testing (PGT), the incorporation of patient genotype data into the practice of medicine is becoming more pervasive. Multiple medical centers across the country have begun introducing genetic and genome-wide analysis to make pharmacoge... | {
"pile_set_name": "PubMed Central"
} |
There are several errors in Table 2. Please refer to the corrected version of Table 2 here:
{#pone-a8dfd4ee-f4b7-443e-bf78-ebb0dab4e55b-g001}
**Competing Interests:**No competing interests declared.
| {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The role of growth hormone (GH) in growth promotion is well known by clinicians, however, less appreciated is its effect on metabolism in the well state. In 1936, Bernardo Houssay, M.D. in the New England Journal of Medicine, proposed that the anterior pituitary gland after the ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
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Liver cirrhosis has an increasing incidence in the general population. It is estimated that, in Europe, there are 170,000 annual deaths due to this cause with major differences between regions. Thus, in the south-east cirrhosis mortality rate is 10-20 times higher than the rest of t... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
1. Introduction {#s0005}
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Severe myoclonic epilepsy of infancy (SMEI), also known as Dravet syndrome, is an epileptic encephalopathy that presents during the first year of life and is one of the most severe types of infant epilepsy that is resistant to drugs [@bb0005; @bb0010].
Patients with Dravet syn... | {
"pile_set_name": "PubMed Central"
} |
One and a half billion people live in conflict-affected and fragile states. At the last estimate in 2012, 172 million people were directly affected by war, including refugees, internally displaced people and those who were affected but did not flee.[@R1]^,^[@R2] Children are twice as likely to be malnourished and twice... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
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Turner's syndrome (TS) is depicted as a total or partial absence of one X chromosome, and occurs in approximately 1/2200 of live born females \[[@CR1]\]. Nearly 43-49 % of the patients are cases with classical TS who are monosomic for X chromosome (45,X). The remaining patients are mosaic... | {
"pile_set_name": "PubMed Central"
} |
Measurement of cerebral blood flow (CBF) is of interest, both in the clinical setting and for research. Absolute quantification of global CBF is of key importance when investigating factors affecting the entire brain, eg, altered physiological states or aging.[1](#jmri25442-bib-0001){ref-type="ref"}, [2](#jmri25442-bib... | {
"pile_set_name": "PubMed Central"
} |
This article is part of the thematic issue \"Frontiers in pharmaceutical nanotechnology\".
Introduction
============
Nanocrystals for pharmaceutical use were invented in the early 1990s \[[@R1]--[@R4]\]. They are composed of 100% substance, are stabilized with only small amounts of surfactants, and possess particle s... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-19-03456}
===============
Potassium (K^+^) is an essential macronutrient and is essential for plant growth and development \[[@B1-ijms-19-03456]\]. K^+^ is associated with or involved in several physiological processes that support plant growth and development, such as photosynthesis, enzym... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
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In arid and semi-arid environments, environmental gradients differ at local scales because shrubs generally improve soil fertility and produce microclimates under their canopies that favor plant-plant inte... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Stress myocardial perfusion imaging using single-photon emission computed tomography (SPECT) is commonly used for risk stratification and therapeutic decision making in patients with coronary artery disease (CAD).[@B1][@B2][@B3] Since ischemia is a strong predictor of adverse outcomes, such a... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Zhang J, Gao X, Han Y, *et al*. Treatment effects of systematic two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions: rationale and design of a prospective, randomised and multicentre DEFINITION II trial. *BMJ Open* 2018;8:e020019. doi: 10.1136/bmjopen-2017-020019.
The sa... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .92}
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"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Fluid flowmeter calibration methods use a variety of techniques; they include wide ranges of operational parameters; they cover wide ranges of precision and accuracy, \[[@b1-jresv97n5p509_a1b]--[@b3-jresv97n5p509_a1b]\]. Increasingly, the diverse improvements being sought for flowmeters... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The mutation of p53 protein is one of the frequent causes of human cancer since it has a key role in numerous cell stability and proliferation functions^[@CR1]^. On the other hand, MDM2 is an oncogene protein that negatively regulates p53^[@CR2]^. MDMX (MDM4) is also a homolog for MDM... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
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Early supported discharge (ESD) with continued rehabilitation in the home has been shown to be beneficial among patients with mild to moderate stroke. The ESD- model for rehabilitation was introduced in the late 1990s and includes an interdisciplinary team with appropriate recourses that ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Bladder cancer is one of the most common malignant tumors. Most cases progress to high-grade invasive cancer despite long-standing intravesical therapies. Novel therapeutic treatment options are urgently needed to improve the overall treatment success rates for localized bladder cancer^\[^[@r... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
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Osteoporosis is a prevalent bone disease that is defined by a low bone mass and an increased risk of fractures \[[@B1]\]. Adequate regulation of bone remodeling in adulthood is essential to maintain a healthy bone mass \[[@B2]\]. However, an imbalance between bone formation and ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
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Dancing is a very rare seizure semiology. To the best of our knowledge, there have been only a few case reports of ictal dancing or dancing-like movement. The previous reports provided either of description only or video only; or the case could hardly be called dancing. The "dancing epile... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijerph-17-01813}
===============
The current evidence-based paradigm requires that the most reliable scientific evidence is used to increase patient safety by predicting how a certain intervention might affect health and well-being. This is true both in a strictly clinical context, where doctors... | {
"pile_set_name": "PubMed Central"
} |
Background
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Schizophrenia is a severe mental disorder with grave personal and social costs \[[@B1]\]. Approximately 1% of the population develops schizophrenia during their lifetime. Over the years, many genes have been reported to be responsible for the susceptibility to schizophrenia \[[@B2]\]. In general,... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Many attempts have been made to use breeding or molecular biological methods to modify the ability to produce secondary metabolites in medicinal plants. Among the challenges being addressed, manipulations of the morphine biosynthesis in the opium poppy (*Papaver somniferum* L.), particu... | {
"pile_set_name": "PubMed Central"
} |
Learning pointsManagement decisions appropriate for a non-athlete might be inappropriate in an athlete as they may result in disqualification, financial loss, or put the athlete at additional risk of complications.Cardiologists with expertise in sports cardiology should be involved in the management of athletes as it i... | {
"pile_set_name": "PubMed Central"
} |
Full text
=========
A new term, \'selective estrogen receptor modulator\'; (SERM), has infiltrated the estrogen receptor (ER) literature lately \[[@B1]\]. It is nothing more than the reaffirmation of an old fact, namely that different estrogens have different effects, in different tissues. The major natural estrogens ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
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The assessment of human daily physical activity in population studies requires accurate, cheap, and feasible measurement technology [@pone.0061691-Corder1], [@pone.0061691-Wareham1], [@pone.0061691-Wong1]. Accelerometers are increasingly being used for physical activity assessment and m... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
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Prion diseases, such as bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep, and Creutzfeldt-Jakob disease (CJD), kuru and Gerstmann-Sträussler-Scheinker (GSS) syndrome in humans, are a group of neurodegenerative disorders caused by prions, self-replicating β-sheet-rich... | {
"pile_set_name": "PubMed Central"
} |
Key Points {#Sec1}
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CBD has been reported to exert a number of physiological, biochemical, and psychological effects that have the potential to benefit athletes.The available evidence is preliminary, at times inconsistent, and largely based on preclinical studies involving laboratory animals.Rigorous, contro... | {
"pile_set_name": "PubMed Central"
} |
###### Strengths and limitations of this study
- This study is the first to evaluate the risk of bias in the randomised controlled trials referenced in the guidelines for cardiopulmonary resuscitation.
- A detailed protocol for risk of bias assessments was used to ensure reproducibility and transparency in the ev... | {
"pile_set_name": "PubMed Central"
} |
The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper.
Introduction {#s1}
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The prevalence of heart failure including systolic and diastolic functional impairments continues to increase representing a major health problem [... | {
"pile_set_name": "PubMed Central"
} |
Introduction
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In 2010, the Carnegie Foundation made recommendations to fundamentally change medical education.[@b1-amep-5-289] It called for curricular reforms that would provide earlier exposure to clinical work, more hands-on experiential learning, and a greater focus on care coordination and working wit... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#h0.0}
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The therapeutic benefit of drugs depends on achieving high potency toward the target (an enzyme, cell, bacterium, parasite, virus, etc.) while avoiding damage to the host organism. One approach to killing tumor cells has been to use highly potent bacterial and plant toxins that act ca... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Dear Editor,
We reviewed the manuscript recently published by Cumhur Cure M, et al. \[[@CR1]\], regarding colchicine and COVID-19. The authors discussed the effects of colchicine in intracellular and extracellular pH conditions and argued that low pH levels secondary to colchicine may increase the viral load of SARS-C... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
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In Europe, on average 70% of total expenditure on dental care is private expenditure and 16% of this private expenditure is covered by complementary dental insurance (CDI) \[[@CR1]\]. However, most CDI products currently on the market in Belgium, France, Germany, and the Netherlands a... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The post thrombotic syndrome
----------------------------
The post thrombotic syndrome (PTS) (sometimes called \'post-phlebitic syndrome\') is a chronic condition that develops in 20--40% of patients within 1--2 years after symptomatic deep venous thrombosis (DVT). A severe form, which can inclu... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Overweight and obesity correspond to an abnormal or excessive fat accumulation, defined as a Body Mass Index (BMI) ≥ 25.0 kg/m^2^ and ≥30 kg/m^2^, respectively \[[@B1]\]. These chronic situations described as epidemic should be considered as pandemic with a prevalence that has m... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Fish, marine oils, and their concentrates all serve as sources of the two marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as do some products from algae. To demonstrate an effect of EPA + DHA on heart health, a number of randomized, controlled inte... | {
"pile_set_name": "PubMed Central"
} |
DOI: [10.1002/bjs5.50177](https://doi.org/10.1002/bjs5.50177)
*The Editor‐in‐Chief welcomes topical correspondence from readers relating to articles published in BJS Open. Letters should be submitted via ScholarOne Manuscripts and, if accepted, will be published online*.
We read with interest the work of Charehbili a... | {
"pile_set_name": "PubMed Central"
} |
Debates over fundamental concepts in quantum theory such as reality, locality and quantum entanglement not only deepen our understanding of quantum mechanics but also promote the development of quantum information technology. One of such debates, which has existed since the beginning of quantum mechanics, is whether th... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Our understanding of the genetic basis of Parkinson's disease (PD) has increased tremendously over the past 20 years. Mutations in the gene encoding alpha-synuclein (α-syn) were the first to be associated with genetic PD. Another monogenic causative factor in PD patients is *leucine-rich ... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#s1}
================
Metabolic syndrome (MetS) refers to a cluster of metabolic disorders such as hyperglycemia, insuline resistance, type II diabetes mellitus, and hyperlipidemia which cause obesity and cardiovascular diseases [@b1]. Diet quality is a strong predictor of this syndrome [@b1],[@b2]. ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
There is a clinical need for efficient and cost-effective grafts in urethral reconstructive surgery. Current surgical techniques require harvesting from autologous sites eg. buccal mucosa and penile skin tissue^[@CR1]^. This increases the risk of complications, the possible lack of ti... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The methylenetetrahydrofolate reductase enzyme (MTHFR) catalyzes a reaction that produces 5-methyltetrahydrofolate (5-methylTHF), the methyl donor for homocysteine in the synthesis of methionine. The 677C\>T mutation of the *MTHFR*gene has been associated with a thermolabile enzyme with decreased... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Papaya mosaic virus (PapMV) is a member of the large family of *Flexiviridae* in the genus *Potexvirus*. The virus has a flexuous rod shape of 500 nm in length and 13 nm in diameter \[[@B1]\]. The CP, made mostly of alpha helices \[[@B2]\], is composed of 215 amino acids and has an estimated mole... | {
"pile_set_name": "PubMed Central"
} |
**PURPOSE:** The face and craniofacial skeleton (CFS) make up a complex 3D structure that is critical to human function and cosmesis. Traumatic injury to the CFS requires fracture treatment to both allow the recovery of mechanical function and forms a foundation for the restoration of soft tissue anatomy. CFS reconstru... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
In wild sika deer, *Cervus nippon yesoensis*, in Hokkaido, Japan, sarcocysts of protozoan parasites of the genus *Sarcocystis* are highly prevalent, and four *Sarcocystis* species have been identified in the region to date: *S. ovalis*, *S. pilosa*, *S. tarandi*-like, and *S. tr... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
The occurrence and undesirable complications from healthcare-associated infections have been well recognized in the literature for the last several decades \[[@B1-ijerph-09-03330]\]. The most common sources of infectious agents causing healthcare associated infections, described in a sc... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Knowledge of internal dental morphology is an extremely important step in planning and administering endodontic therapy.\[[@ref1]\] The numerous anatomical variations existing in the root canal system may contribute to the failure of root canal therapy. Failure to explore and instru... | {
"pile_set_name": "PubMed Central"
} |
Sir,
A forty-nine year-old male underwent live related renal transplantation thirteen years ago for end stage renal disease secondary to bilateral vesicoureteric reflux. He was on prednisolone 10 mg per day and azathioprine 125 mg per day for maintenance immunosuppression. He presented with pain in his abdomen and vom... | {
"pile_set_name": "PubMed Central"
} |
Lead is one of the most useful elements in industry, but serves no useful function in the human body. Environmental and industrial lead exposures continue to pose major public health problems in the exposed population.\[[@CIT1]\] Over the years, it has become increasingly evident that low-level lead exposure resulting ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-jcm-08-01780}
===============
While numerous guidelines for the management of mild traumatic brain injury (TBI) exist, there is still controversy regarding the treatment of head trauma patients with antithrombotic therapy (ATT). The management of mild TBI on ATT is complicated by the heterogenei... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-biomolecules-10-00575}
===============
Aflatoxin is a type of secondary metabolite produced mainly by microscopic fungal species *Aspergillus flavus* and *Aspergillus parasiticus* in the environment of high temperature and humidity (temperature 25--30 °C, moisture \> 15%) \[[@B1-biomolecules-10-... | {
"pile_set_name": "PubMed Central"
} |
In the most recent version of the projections of the Office of the Actuary in the Centers for Medicare & Medicaid Services, national health spending growth is expected to average 5.5% per year for 2017-2026 in the United States (US): approximately 1.0% higher than projected gross domestic product (GDP) growth.^[@bibr1-... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
See related research by Switzer et al., <http://breast-cancer-research.com/content/14/5/R125>
Unlike the constitutive nitric oxide (NO) synthase isoforms, the inducible isoform of NO synthase - nitric oxide synthase 2 (NOS2) - is capable of producing sustained intracellular levels of NO, and it is increasingly appreci... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Over the past decade, there has been an increasing emphasis among university educators on globalization and internationalization, and global health programs and international experience have become key areas of focus for university professionals. According to China's Ministry of Education... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript and its Supporting Information files.
1 Introduction {#sec001}
==============
The formation of stable aggregates is very common in nature. For example, long-range attraction through chemotaxis can lead to aggregation of Dictyostelium cells \[[@pone.0222371.ref001]\] or euka... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death in the world with more than 788,000 death per year based on data presented in the World Health Organization (WHO). HCC is the most common liver malignancy with risk factors to the liver such as chronic viral hepat... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Plate tectonics has reshaped the distribution of the Earth's continental and oceanic lithosphere through time. However, when modern-style plate tectonics started is still debated, with proposals ranging from the Neoproterozoic Era to the Archean Eon^[@CR1]--[@CR7]^. The absence from t... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
Colon cancer is one of the most common malignant cancers and among the leading causes of cancer-related deaths worldwide.[@CIT0001] The combination therapy of oxaliplatin and fluoropyrimidine has been the standard adjuvant therapy in patients with stage III/IV colon cancer. However, ... | {
"pile_set_name": "PubMed Central"
} |
Optimal patient care relies on a cohesive team of health care professionals who work synergistically, focusing on individual strengths to ensure the highest quality of patient care ([@CIT0001], [@CIT0002]). It has been shown that interprofessional collaboration enhances patient safety, decreases medical errors, and imp... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
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Cytomegalovirus (CMV) is a re-emerging human herpes virus, which causes substantial morbidity and occasional mortality in immunocompromised patients \[[@CIT0001]\]. Among these, solid organ transplant recipients who maintain an allograft by receiving immunosuppressive drugs are well-kno... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
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*Toxoplasma gondii* is an obligate intracellular apicomplexan protozoan parasite that can infect all warm-blooded animals, mainly through oral and congenital infections (Tenter et al., [@B34]; Elmore et al., [@B11]; Zhou et al., [@B39]). This parasite has a significant medical and socio... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
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Sensory experience plays an essential role in establishing and refining neural organization during development. In fact, abnormal input or experiential modifications due to injury can produce severe changes in neuronal morphology including alterations in dendritic length, cell size, and... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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According to sexual conflict theory females are the choosy sex ([@zow090-B63]; [@zow090-B41]; [@zow090-B7]) and should choose males of higher quality as potential mates ([@zow090-B75], [@zow090-B76]; [@zow090-B5]; [@zow090-B31]; [@zow090-B38]; [@zow090-B32]; [@zow090-B30]). By choosing a high quality partner the female... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The prevalence of diabetes mellitus is increasing worldwide with approximately half of all persons with diabetes living in Asia \[[@B1]\]. The herb fenugreek (*Trigonella foenum-graecum* L., Fabaceae family) is used both in cooking and for the treatment of diabetes in many parts of the world,... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec001}
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Oropharyngeal candidiasis (OPC) occurs in a diverse group of patients. Risk factors for OPC include the use of dentures, corticosteroid inhalers, cigarettes, broad-spectrum antibiotics, and immunosuppressive and chemotherapeutic agents. Patients with HIV, diabetes, and iatrogenic or... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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Key question {#Sec1}
============
Does hypo-attenuated leaflet thrombosis occur in bioprosthetic mitral valve?
Key finding {#Sec2}
===========
Hypo-attenuated leaflet thrombosis was observed in patients who underwent bioprosthetic mitral valve replacement.
Take-home message {#Sec3}
=================
Although rare,... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Electrophysiology in audiology is an objective tool to check the integrity of the auditory system. Auditory evoked potentials are electrophysiological tests, which give information about a number of events happening in the peripheral and central nervous systems that are generall... | {
"pile_set_name": "PubMed Central"
} |
In the wild, feral cats typically eat small mammals, reptiles, birds and insects. It is often not possible to mimic natural feeding behaviours of feral cats. Extruded diets have been the traditional alternative fed to domestic cats. Commercial chicken-based extruded diets (EXT) have complex diet formulations, including... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
INTRODUCTION {#s1}
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Lung cancer is the leading cause of cancer-related deaths worldwide, with non-small cell lung cancer (NSCLC) accounting for approximately 85% of all cases \[[@R1]\]. Most NSCLC patients are diagnosed at an advanced stage and have a 5-year survival rate of less than 20% \[[@R1], [@R2]\] ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Brucellosis is the collective name of a group of zoonotic diseases afflicting a wide range of domestic and wild mammals ([@B75]; [@B77]). In domestic livestock brucellosis is manifested mostly as abortions and infertility, and contact with infected animals and consumption of unpasteurized dai... | {
"pile_set_name": "PubMed Central"
} |
Ischemia-reperfusion injury represents a pathological condition characterized by an initial undersupply of blood to an area or organ followed by a restoration of perfusion and concomitant reoxygenation (= reperfusion). Ischemia typically occurs in the presence of embolism or thrombosis but can also be triggered by surg... | {
"pile_set_name": "PubMed Central"
} |
About 1 in every 10 adults worldwide is overweight or obese[@b1] and obesity is a risk factor for morbidity and mortality from cardiovascular diseases, diabetes, certain cancers, and musculoskeletal disorders. Despite strong interest in research addressing obesity, safe and effective pharmacological options for the pre... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Introduction
============
A giant retinal tear (GRT) is defined as a full-thickness break in the retina equal to or larger than 3 clock hours associated with vitreous detachment.[@b1-opth-12-2053] Risk factors for developing a GRT include trauma, high myopia, Marfan syndrome, Stickler's syndrome or other hereditary vi... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#S1}
===============
Water is essential for sustaining all life forms and access to clean and safe drinking water is a basic human need. Latest estimates of the Joint Monitoring Programme for Water Supply and Sanitation state that the world is on track to meet the Millennium Development Goals target f... | {
"pile_set_name": "PubMed Central"
} |
Abedi E, Pourmohammadi K, Abbasi S. Dual‐frequency ultrasound for ultrasonic‐assisted esterification. Food Sci Nutr. 2019;7:2613--2624. 10.1002/fsn3.1115
1. INTRODUCTION {#fsn31115-sec-0001}
===============
Starch is an accessible, thickening, and texturizing stabilizer, and of paramount importance when it comes to a... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
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Lysosomes and the ubiquitin proteasome system (UPS) are major degradation machineries for damaged and unwanted cellular contents in eukaryotic cells. The UPS degrades damaged and unwanted proteins that are tagged with ubiquitin, whereas large protein aggregates and damaged or dispensabl... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Endothelial cell adhesion molecules (\'ECAMs\') play essential roles in the development of chronic inflammation by recruiting leukocytes, especially lymphocytes to tissues. ECAMs support several forms of leukocyte adhesion including rolling, firm adhesion and extravasation \[[@B1]\]. Infiltration... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Introduction {#S1}
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Skin with underlying subcutis is armed with neuroendocrine capabilities and represents the largest and one of the most complex organs in the human body ([@R58]). Strategically located at the interface with external environment, skin detects, integrates, and responds to stressors includi... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
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One of the most frequently deregulated pathways in human cancers is the phosphoinositide 3-kinase (PI 3-K) and Akt signaling cascade \[[@R1]\]. This is particularly evident in breast cancer where mutations exist in virtually all of the proteins that lead to activation of PI 3-K and its ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-17-01969}
===============
Glycosylation is a posttranslational modification that is found on about 50% of all proteins, in particular on secreted and transmembrane proteins of eukaryotes, archaea and to a lesser extent in prokaryotes \[[@B1-ijms-17-01969],[@B2-ijms-17-01969],[@B3-ijms-17-01... | {
"pile_set_name": "PubMed Central"
} |
Visual working memory (VWM) is a cornerstone of human visual cognition. It temporarily retains visual information and makes it accessible for cognitive operation, report, and action control (Eriksson et al. [@CR10]; Oberauer [@CR32]; Poth and Schneider [@CR38]; Schneider [@CR48]). VWM has only limited capacity (Luck an... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
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"pile_set_name": "PubMed Central"
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Introduction
============
CTLs are crucial for the defense against many invading organisms and certain tumors. Presentation of antigenic peptides bound to MHC class I molecules is a prerequisite for stimulation of a CTL response, and therefore plays a pivotal role in providing CTLs with the capacity to respond to fore... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Soft tissue defects around the foot and ankle region often present an awkward problem to the orthopaedic surgeons. Tendons and bones are frequently exposed after trauma because of the thinness of the subcutaneous tissue. Traditionally, local flaps were used for resurfacing but their use is limite... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .277}
{#sp2 .278}
{#sp3 .279}
{#sp4 .280}
{#sp5 .281}
{#sp6 .282}
{#sp7 .283}
{#sp8... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Increased population density and movement of people around the globe have generated a rise in the number of outbreaks of infectious diseases and led to the emergence of new infectious diseases \[[@B1]\]. Worldwide, 3.575 million people die each year from water-related diseases \[[@B2]\]. The wate... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Body size, a key trait for all organisms, affects various aspects of survival and reproduction of individuals in their interactions with their physical and biological environments. In animals, divergence of body size among related populations is often related to adaptation to differin... | {
"pile_set_name": "PubMed Central"
} |
(J Am Heart Assoc. 2020;9:e015118 DOI: 10.1161/JAHA.119.015118.)31992159
Clinical PerspectiveWhat Is New?The present study is the first population‐based, untargeted metabolomic analysis of left ventricular diastolic function in a biracial (35% black, 65% white) community‐based sample of middle‐aged adults**.**We found... | {
"pile_set_name": "PubMed Central"
} |
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