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032dad3d59669c324774b0aa1256f76c8f34876110dc4463b65122b1b415c729/peer_review/images_list.json

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03958f873bda5dcf088e0d766c000075ed7adb61f8e7f76a9a5c0ea0d50554df/peer_review/images_list.json

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+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Integrated scRNA-Seq data showing consistency of clustering between individual and integrated data types.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Integrated scATAC-Seq data showing consistency of clustering between individual and integrated data types.",
+    "bbox": [
+      [
+        200,
+        602,
+        771,
+        818
+      ]
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03a74308dd22e6d95943be0ac25db777eeea49e185e458d3fb917f6f378c9923/peer_review/images_list.json

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+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_5.jpg",
+    "caption": "Fig. 5. Optical and mechanical properties of microstructures. (c) Top view of SEM image of UPstextured silicon wafer obtained by etching in (B). (d) Schematic diagram of sunlight reflection on UPstextured silicon wafer. (e) Reflectance spectrum of standard silicon wafer, and UPs-textured silicon wafer without and with trapping effects of microstructures responding to sunlight. The experimental parameters are \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(U = 400 \\mathrm{Vpp}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [
+      [
+        145,
+        284,
+        854,
+        393
+      ]
+    ],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "Fig. 3. Fabrication of multi-height gradients microstructure. (a) Response time and OM images between on and off state at \\(z = 150 \\mu \\mathrm{m}\\) . Diffraction patterns of (b) simulation at \\(z = 1060 \\mu \\mathrm{m}\\) and (c) experiment at \\(z = 1078 \\mu \\mathrm{m}\\) , and the corresponding (d) 2D profile image and (e) 3D surface topography of the fabricated height gradient microstructures through one-step lithograph. The scale bar denotes 10 \\(\\mu \\mathrm{m}\\) . (f) Normalized intensity along the representative dashed line in (c) and (e). The experimental parameters are given as follows: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(U = 400 \\mathrm{Vpp}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [
+      [
+        202,
+        437,
+        787,
+        688
+      ]
+    ],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5.jpg",
+    "caption": "Fig. 5. Optical and mechanical properties of microstructures. (a) Experimentally observed OM image of diffraction pattern, corresponding (b) 3D surface topography of microstructures obtained via the lithography: (top) the 3D data model from 3D surface topography and (bottom) the simulated mechanical response of the microstructure at different angles at a specific distance ( \\(z = 3400 \\mu \\mathrm{m}\\) ). (c) Top view of SEM image of UPs-textured silicon wafer obtained by etching in (B). (d) Schematic diagram of sunlight reflection on UPs-textured silicon wafer. (e) Reflectance spectrum of standard silicon wafer, and UPs-textured silicon wafer without and with trapping effects of microstructure responding to sunlight. The experimental parameters are \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(U = 400 \\mathrm{Vpp}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R1. Schematic diagram of light propagation.",
+    "bbox": [
+      [
+        303,
+        650,
+        680,
+        805
+      ]
+    ],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure R2. The resultant SEM image of electrode.",
+    "bbox": [],
+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure R1. Schematic diagram of light propagation.",
+    "bbox": [
+      [
+        313,
+        467,
+        668,
+        611
+      ]
+    ],
+    "page_idx": 15
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1. Design concept and principle. (b) Calculated NLC molecular distributions along the \\(z\\) -axis driven by an electric field (1 kHz, 400 Vpp), and NLC molecular orientation of \\(x - z\\) plane aligning to the electric field lines (E).",
+    "bbox": [
+      [
+        352,
+        92,
+        640,
+        406
+      ]
+    ],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "Fig. 3. Optical characterization of experimentally fabricated multi-height gradients microstructure. (a) Response time and OM images between on and off state at \\(z = 150 \\mu \\mathrm{m}\\) . The experimental parameters are given as follows: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(U = 400 \\mathrm{Vpp}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [
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+        528,
+        612,
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+      ]
+    ],
+    "page_idx": 17
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure R1. (a) Schematic diagram of NLC device. (b) The schematic diagram of the initial orientation of NLC molecules based on the Hyflon coated electrode surface (top), and corresponding the image of polarized optical microscope of the NLC device (bottom). (c) The schematic diagram of NLC molecular orientation driven by an electric field.",
+    "bbox": [
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+      ]
+    ],
+    "page_idx": 18
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Figure R1 Simulated OM images of diffraction patterns obtained (a) without and (b) with a linear polarizer before the charge coupled device (CCD) when different voltages were applied ( \\(U = 0\\) , 20, 40, 60, 80, 100, 200, 300, 400 Vpp). The parameters of the sample in the experiment are given as follows: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [],
+    "page_idx": 21
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Figure R3 (a) Simulated and (b) experimental OM images of diffraction patterns obtained a1, b1 with and a2, b2 without a linear polarizer before the camera. The experimental parameters are given as: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.39.77 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(\\lambda = 405 \\mathrm{nm}\\) , and \\(U = 400 \\mathrm{Vpp}\\) .",
+    "bbox": [],
+    "page_idx": 22
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_6.jpg",
+    "caption": "Supplementary Fig. 6 a Experimentally observed OM images at \\(R = 0.289\\) , and b corresponding calculated NLC molecular orientations of \\(x\\) -z plane, aligning with the electric field (E) when \\(D = 29.87 \\mu \\mathrm{m}\\) , \\(L = 10.13 \\mu \\mathrm{m}\\) ; and \\(D = 35.05 \\mu \\mathrm{m}\\) , \\(L = 5.95 \\mu \\mathrm{m}\\) , respectively. Experimental parameters are: \\(H = 50 \\mu \\mathrm{m}\\) , \\(U = 400 \\mathrm{Vpp}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [],
+    "page_idx": 23
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1 Design concept and principle. a Experimental setup and achieved diffraction patterns of the proposed dynamic photomask when the laser beam passes it. b Top: spatial distribution of calculated NLC molecular directors along the \\(z\\) -axis driven by an electric field (1 kHz, 400 Vpp); bottom: distribution map of NLC director's tilt angle \\((\\theta)\\) of \\(x\\) - \\(z\\) plane aligning to the electric field (E). The inset highlighted with green rectangle depicts the enlarged part of \\(x\\) from 5 to \\(20\\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(9\\mu \\mathrm{m}\\) ; the inset highlighted with pink rectangle detail shows the director of each LC molecule \\(x\\) from 8 to \\(12\\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(2\\mu \\mathrm{m}\\) ; the inset highlighted with black circle defines the tilt angle \\(\\theta\\) . c Experimentally observed OM image of diffraction pattern, d corresponding 3D surface topography of the microstructure obtained via one-step lithography, and e transferred microstructure on silicon wafer at \\(z = 2530\\mu \\mathrm{m}\\) . Note: LP-linear polarizer, and QWP-quarter waveplate. The sample parameters are given as: \\(D = 20.11\\mu \\mathrm{m}\\) , \\(L = 19.89\\mu \\mathrm{m}\\) , \\(H = 50\\mu \\mathrm{m}\\) , \\(U = 400\\mathrm{Vpp}\\) , and \\(\\lambda = 405\\mathrm{nm}\\) .",
+    "bbox": [
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+      ]
+    ],
+    "page_idx": 25
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1 Design concept and principle. b bottom: distribution map of NLC director's tilt angle \\((\\theta)\\) of \\(x\\) - \\(z\\) plane aligning to the electric field (E). The inset highlighted with green rectangle depicts the enlarged part of \\(x\\) from 5 to \\(20 \\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(9 \\mu \\mathrm{m}\\) ; the inset highlighted with pink rectangle detail shows the director of each LC molecule \\(x\\) from 8 to \\(12 \\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(2 \\mu \\mathrm{m}\\) ; the inset highlighted with black circle defines the tilt angle \\(\\theta\\) .",
+    "bbox": [],
+    "page_idx": 26
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_6a.jpg",
+    "caption": "Fig. 2 Spatial evolution of the diffraction patterns. b Normalized intensity along the selected yellow dashed line in the OM images of experimental diffraction patterns in Supplementary Fig. 6a with \\(D = 29.87 \\mu \\mathrm{m}\\) , \\(L = 10.13 \\mu \\mathrm{m}\\) and \\(D = 35.05 \\mu \\mathrm{m}\\) , \\(L = 5.95 \\mu \\mathrm{m}\\) , when \\(R = 0.289\\) , \\(H = 50 \\mu \\mathrm{m}\\) and \\(\\lambda = 405 \\mathrm{nm}\\) .",
+    "bbox": [],
+    "page_idx": 27
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_6.jpg",
+    "caption": "Figure R1. Simulated diffraction patterns at specific distances ( \\(z = 0\\) , 10, 40, 80, 100, 150, 200, 500, 1000, 1500, 2000, 2500, 3000, 3500 \\(\\mu \\mathrm{m}\\) ), when \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) . The scale bar denotes \\(10 \\mu \\mathrm{m}\\) .",
+    "bbox": [],
+    "page_idx": 28
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Fig. 2 Spatial evolution of the diffraction patterns. c Normalized intensity at a representative dashed line in the simulated diffraction pattern with different LC layer thickness ( \\(H = 1\\) , 5, 9, 30, \\(50 \\mu \\mathrm{m}\\) ) when \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(\\lambda = 405 \\mathrm{nm}\\) and \\(R = 0.560\\) .",
+    "bbox": [
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+    ],
+    "page_idx": 29
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_7.jpg",
+    "caption": "Supplementary Fig. 7 a Simulated diffraction patterns with \\(H = 1\\) , 5, 9, 30, and \\(50 \\mu \\mathrm{m}\\) . b Experimentally observed OM images and c corresponding \\(Z_{\\mathrm{T}}\\) values when \\(H = 30\\) , 50, 80, and \\(100 \\mu \\mathrm{m}\\) . The experimental parameters are: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(R = 0.56\\) , \\(U = 400 \\mathrm{Vpp}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1 Design concept and principle. b Top: spatial distribution of calculated NLC molecular directors along the \\(z\\) -axis driven by an electric field (1 kHz, 400 Vpp); bottom: distribution map of NLC director's tilt angle \\((\\theta)\\) of \\(x - z\\) plane aligning to the electric field (E). The inset highlighted with green rectangle depicts the enlarged part of \\(x\\) from 5 to \\(20\\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(9\\mu \\mathrm{m}\\) ; the inset highlighted with pink rectangle details shows the director of each LC molecule \\(x\\) from 8 to \\(12\\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(2\\mu \\mathrm{m}\\) ; the inset highlighted with black circle defines the tilt angle \\(\\theta\\) .",
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+      ]
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1 Design concept and principle. b bottom: distribution map of NLC director's tilt angle \\((\\theta)\\) of \\(x\\) -plane aligning to the electric field (E). The inset highlighted with green rectangle depicts the enlarged",
+    "bbox": [
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+    ],
+    "page_idx": 31
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_3.jpg",
+    "caption": "Supplementary Fig. 3 b Simulated and c experimental OM images of diffraction patterns. In the OFF state (0 Vpp), the NLC molecules exhibited a homeotropic arrangement, resulting in no diffraction pattern. As the electric field was applied, diffraction patterns began to emerge. After 60 Vpp, the director of LC molecules remained almost unchanged. However, the diffraction pattern became visible at 40 Vpp. When the voltage exceeded 60 Vpp, only tiny differences in the diffraction pattern can be observed, which can be ascribed to minute molecule orientation disparity. The parameters of the experiment are given as follows: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 50 \\mu \\mathrm{m}\\) , \\(\\lambda = 405 \\mathrm{nm}\\) , and \\(z = 300 \\mu \\mathrm{m}\\) .",
+    "bbox": [],
+    "page_idx": 32
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_7.jpg",
+    "caption": "Figure R2. Experimentally observed OM images of diffraction patterns respond to voltage ( \\(U = 0\\) , 20, 40, 60, 80, 100, 200, 300, 400 Vpp) with \\(D = 40.23\\) , \\(L = 39.77 \\mu \\mathrm{m}\\) when \\(H = 50 \\mu \\mathrm{m}\\) , \\(\\lambda = 405 \\mathrm{nm}\\) , and \\(z = 300 \\mu \\mathrm{m}\\) . Scale bar denotes \\(20 \\mu \\mathrm{m}\\) .",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_8.jpg",
+    "caption": "Figure R3. (a) Distribution map of negative LC director's tilt angle \\((\\theta)\\) of \\(x - z\\) plane aligning to the electric field (E). The inset with green rectangle depicts the enlarged part of \\(x\\) from 28 to \\(32 \\mu \\mathrm{m}\\) and \\(z\\) from 0 to \\(2 \\mu \\mathrm{m}\\) . (b) Spatial distribution of calculated NLC molecule directors along the \\(z\\) -axis when \\(z = 0.4\\) , 10, \\(19.6 \\mu \\mathrm{m}\\) . The parameters of the experiment are given as follows: \\(D = 20.11 \\mu \\mathrm{m}\\) , \\(L = 19.89 \\mu \\mathrm{m}\\) , \\(H = 20 \\mu \\mathrm{m}\\) , and \\(\\lambda = 405 \\mathrm{nm}\\) .",
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03c32499e771b72a768116d2d769268099064b26a9d65fb9077ed09a0227a18f/peer_review/images_list.json

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+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1 ID continuum modelling results of the BPMEA. (a) Modelled and experimental Faradaic efficiencies of CO for catalyst layer (CL) incorporated with Sustainion (Sus-CL) or Nafion (Naf-CL) as a function of current densities. Comparison of (b) pH, (c) (bi)carbonate concentrations, and (d) CO2 local concentration across CLs at 100 mA cm-2. Profiles of (e) pH, (f) (bi)carbonate ions, and (g) CO2 local concentration across CEL and Sus-CL as a function of proton transference numbers. The bipolar junction is located at \\(x = 0 \\mu \\mathrm{m}\\) , and the CEL/CL is located at \\(x = 75 \\mu \\mathrm{m}\\) . The concentration profiles of the CEL for (c) and (d) are presented in Fig. S2, and not shown here for clarity.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Fig. S1 Model predicted (a) \\(CO_2\\) fluxes and (b) local partial current density of CO evolution within Sus- and Naf-CL.",
+    "bbox": [
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+    ],
+    "page_idx": 5
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Fig. S2 Comparison of (a) the ohmic resistances and (b) cell voltages (solid line) and ohmic losses (dashed lines) of the BPMEA as a function of current densities for CLs based with NiNC-IMI 15 wt% Sus, NiNC-IMI 15 wt% Naf, NiNC-IMI 15 wt% Sus using 1M KOH, and NiNC-IMI 15 wt% Sus with spacer at CEL|cathode interface. The rest of the samples used 0.1 M KOH as the analyte.",
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+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Fig. S3 Comparison of the (a)averaged Nernstian shift and (b) pH values caused by ionomers in the catalyst layers at different current densities estimated from models. Note: the more positive values of the Nernstian shift lead to reduced cell voltages.",
+    "bbox": [
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+    "page_idx": 12
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Fig. S4 Comparison of (a) FEs for CO₂ reduction reaction (CO₂RR) gaseous products, (b) FEs for H₂, (c) partial current density of CO₂RR gaseous product, and (d) cell voltages of BPMEA with NiNC-IMI 15% Sus CL as cathode with recently reported literature data by Yang et al.¹³, Siritanaratkul et al.¹⁴,¹⁵, Yue et al.¹⁶, Xie et al.¹⁷, Li et al.¹⁸, and Eagle et al.¹⁹.",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Fig. S5 (a) NMR spectra of the anolyte after the test. X-ray photoelectron spectroscopy (b) survey and (c) high-resolution spectra of C1s, N1s, and Ni2p3/2 of NiNC-IMI catalyst survey, accompanied by a schematic illustration highlighting distinct functionalities. The Ni-Nx motifs, identified as the Ni states between binding energy between 856 and 854 eV, is proposed as the active site for electrochemical CO₂ reduction. (d) The pore size distribution of the catalyst was evaluated using N₂ physisorption and BET analysis. (e) Transmission electron microscopy image showcasing the as-prepared catalysts. (f) Cross-sectional image illustrating the catalyst layer after spray coating on the electrode. Related data and images for (b)-(f) have been presented in our previous publication by Brückner et al.⁹.",
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+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Fig. S6 Comparison of the (a) averaged Nernstian shift and (b) pH values caused by ionomers in the catalyst layers at different current densities estimated from models. Note: the more positive values of the Nernstian shift lead to reduced cell voltages.",
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+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "The thickness of Derma-tac (alpha-step)",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "The thickness of Derma-tac (Alpha-Step)",
+    "bbox": [],
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+  {
+    "type": "image",
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+    "caption": "Figure R1. Scatterplots for correlations between Post-Pre differences in FA, MD, and FC with individual performance gain (LU and N-back change). Increased FA change was associated with more pronounced gain in N-back task. Increased FC change was associated with more pronounced gain in LU task. Decreased MD changes were associated with FC increases. FA, fractional anisotropy. MD, mean diffusivity. FC, functional connectivity. LU, letter updating. Blue bars/points/0: sham group. Orange bars/points/1: anodal tDCS group. \\(p < 0.10 * p < 0.05 ** p < 0.01\\)",
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+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure R2. Electric field distribution of the applied stimulation protocol on an MNI brain using SimNibs \\(^{74}\\) anode centered over the left dorsolateral prefrontal cortex (F3, 5-cm diameter, 1 mA) and return (cathode) centered over the contralateral supraorbital region (Fp2, 5-cm diameter, 1 mA). Field magnitude below the anodal electrode: \\(\\sim 0.15 \\mathrm{~V} / \\mathrm{m}\\). LH, left hemisphere.",
+    "bbox": [
+      [
+        230,
+        288,
+        763,
+        389
+      ]
+    ],
+    "page_idx": 12
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure R4. Overlay of the canonical tract derived from the probabilistic tractography (yellow) and the JHU WM atlas labels (multicolored). SLF, superior longitudinal fasciculus. CC, corpus callosum. LH, left hemisphere.",
+    "bbox": [],
+    "page_idx": 14
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure R5. White matter pathways' microstructure (fractional anisotropy, FA) in two specific fiber tracts of interest (Corpus callosum, CC, and left superior longitudinal fasciculus, SLF) reconstructed using FreeSurfer's TRACULA (v7). The display shows the respective tract in a sample subject (overlaid on the individual FA image). FA along the CC was increased after the intervention in anodal compared to sham group for those individuals with initially higher FA in the tract. FA along the SLF did not change through the intervention.",
+    "bbox": [
+      [
+        134,
+        205,
+        860,
+        432
+      ]
+    ],
+    "page_idx": 21
+  }
+]

04d3558bc25d9db827f2354105dafd0c48aaa7a3d6a779cac218c84fc60a09bd/peer_review/images_list.json

@@ -0,0 +1,310 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Table 1. Photocatalyst screening for C-C cross-coupling reactions<sup>a</sup>",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Table 2. Substrate scope \\(^{a,b}\\)",
+    "bbox": [
+      [
+        115,
+        100,
+        880,
+        400
+      ]
+    ],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Figure 1. Photoredexcatolytic C(Ar)-C(Ar) cross-coupling reactions. a,b, Previous (a) and our (b) methods for photocatalytic C(Ar)-C(Ar) cross-coupling reactions. c, Comparisons of excited-state lifetime and excited-state oxidation potentials of representative photocatalysts and Au(BZI)(TMCz). Shown at the bottom are chemical reducing agents. Refer to Supplementary Tables 1 and 2 for the values. d, UV-Vis absorption spectrum of \\(10\\mu \\mathrm{M}\\) Au(BZI)(TMCz) recorded in toluene at 298 K. Inset figures denote the hole and electron distributions calculated for the singlet transition of the triplet geometry of Au(BZI)(TMCz) with exclusive ligand-to-ligand charge transfer (LLCT) transition character.",
+    "bbox": [
+      [
+        115,
+        90,
+        884,
+        580
+      ]
+    ],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Fig. Photoluminescence decay traces. Photoluminescence decay traces of five independently prepared solutions of \\(\\mathrm{Au(BZI)(TMCz)}\\) ( \\(50 \\mu \\mathrm{M}\\) in de-aerated toluene) recorded after \\(377 \\mathrm{nm}\\) pulsed laser excitation (time duration \\(= 0.8 \\mathrm{ns}\\) ).",
+    "bbox": [
+      [
+        283,
+        234,
+        690,
+        505
+      ]
+    ],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Fig. Excited-state oxidation potentials and lifetimes of reported two-coordinate metal complexes.",
+    "bbox": [
+      [
+        328,
+        87,
+        672,
+        504
+      ]
+    ],
+    "page_idx": 11
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Figure 1. Photoredexcatolytic C(Ar)-C(Ar) cross-coupling reactions. a,b, Previous (a) and our (b) methods for photocatalytic C(Ar)-C(Ar) cross-coupling reactions. c, Comparisons of excited-state lifetime and excited-state oxidation potentials of representative photocatalysts and Au(BZI)(TMCz). Shown at the bottom are chemical reducing agents. Refer to Supplementary Tables 1 and 2 for the values. d, UV-Vis absorption spectrum of 10 \\(\\mu \\mathrm{M}\\) Au(BZI)(TMCz) recorded in toluene at 298 K. Inset figures denote the hole and electron distributions calculated for the singlet transition of the triplet geometry of Au(BZI)(TMCz) with exclusive ligand-to-ligand charge transfer (LLCT) transition character.",
+    "bbox": [
+      [
+        115,
+        90,
+        883,
+        580
+      ]
+    ],
+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Figure 2. Oxidative quenching. a, Photoluminescence ( \\(\\lambda_{\\mathrm{ex}} = 380 \\mathrm{nm}\\) ) spectra of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M}\\) Au(BZI)(TMCz), recorded with increasing concentration of 1a (0–100 mM). The peak marked with an asterisk (\\*) is the Raman signal of the solvent. b, Photoluminescence decay traces of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M}\\) Au(BZI)(TMCz), recorded with increasing concentration of 1a (0–100 mM) at a wavelength of \\(540 \\mathrm{nm}\\) after picosecond pulsed laser photoexcitation at \\(377 \\mathrm{nm}\\) (pulse duration \\(= 25 \\mathrm{ps}\\) ). c, Corresponding pseudo-first-order kinetics analysis of the quenching rate as a function of added 1a. The quenching rate was calculated according to the relationship rate \\(= 1 / \\tau_{\\mathrm{obs}}(\\mathrm{1a}) - 1 / \\tau_{\\mathrm{obs}}(0)\\) , where \\(\\tau_{\\mathrm{obs}}(\\mathrm{1a})\\) and \\(\\tau_{\\mathrm{obs}}(0)\\) are the observed photoluminescence lifetime of \\(50 \\mu \\mathrm{M}\\) Au(BZI)(TMCz) in the presence and absence, respectively, of 1a. d, Photoluminescence ( \\(\\lambda_{\\mathrm{ex}} = 380 \\mathrm{nm}\\) ) spectra of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M}\\) Au(BZI)(TMCz) recorded with increasing concentration of DIPEA (0–500 mM).",
+    "bbox": [
+      [
+        288,
+        188,
+        708,
+        510
+      ]
+    ],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Figure 1. Photoredoxcatalytic C(Ar)–C(Ar) cross-coupling reactions. a,b, Previous (a) and our (b) methods for photocatalytic C(Ar)–C(Ar) cross-coupling reactions. c, Comparisons of excited-state lifetime and excited-state oxidation potentials of representative photocatalysts and Au(BZI)(TMCz). Shown at the bottom are chemical reducing agents. Refer to Supplementary Tables 1 and 2 for the values. d, UV–Vis absorption spectrum of \\(10~\\mu \\mathrm{M}\\) Au(BZI)(TMCz) recorded in toluene at 298 K. Inset figures denote the hole and electron distributions calculated for the singlet transition of the triplet geometry of Au(BZI)(TMCz) with exclusive ligand-to-ligand charge transfer (LLCT) transition character.",
+    "bbox": [],
+    "page_idx": 18
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Table 1. Photocatalyst screening for C-C cross-coupling reactions",
+    "bbox": [
+      [
+        115,
+        520,
+        802,
+        875
+      ]
+    ],
+    "page_idx": 19
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_10.jpg",
+    "caption": "Supplementary Fig. 10 Reaction set-up. a, Emission spectrum of blue LEDs. b, Schematic representation of the photoreactor. c,d, Photos showing the photoreactor.",
+    "bbox": [],
+    "page_idx": 23
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Reaction scale: 1 (0.5 mmol) and 2 (5.0 mmol). \\(^{b}\\) Isolated yields, except \\(^{1}\\mathrm{H}\\) NMR yields for 3da and 3ea due to purification challenges from the protodebrominated products.",
+    "bbox": [],
+    "page_idx": 24
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_6.jpg",
+    "caption": "Fig. Photoluminescence ( \\(\\lambda_{\\mathrm{ex}} = 380 \\mathrm{nm}\\) ) spectra of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M} \\mathrm{fac} - \\mathrm{Ir}(\\mathrm{ppy})_3\\) recorded with increased concentrations of DIPEA (0–1000 mM).",
+    "bbox": [],
+    "page_idx": 25
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_7.jpg",
+    "caption": "Fig. Reductive quenching. Photoluminescence ( \\(\\lambda_{\\mathrm{ex}} = 380 \\mathrm{nm}\\) ) spectra of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M} f a c - \\mathrm{Ir}(\\mathrm{ppy})_{3}\\) recorded with increased concentrations of DIPEA (0–1000 mM).",
+    "bbox": [
+      [
+        308,
+        110,
+        692,
+        330
+      ]
+    ],
+    "page_idx": 27
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_1.jpg",
+    "caption": "Supplementary Fig. 1 UV–Vis absorption spectra. UV–Vis absorption spectra (toluene) of \\(10 \\mu \\mathrm{M} \\mathrm{Au}(\\mathrm{I})\\) complexes tested in this study and the LEDs (405 nm) emission spectrum (black). The dotted line is a 10-times amplified absorption spectrum of \\(\\mathrm{Au}(\\mathrm{IPr})(\\mathrm{Cz})\\) .",
+    "bbox": [
+      [
+        308,
+        453,
+        692,
+        671
+      ]
+    ],
+    "page_idx": 27
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_3.jpg",
+    "caption": "Supplementary Fig. 3 Electrochemical potentials. a–c, Cyclic (CV, blue solid curves) and differential pulse voltammograms (DPV, blue dashed lines) of Ar-saturated DMSO containing \\(0.10\\mathrm{M}\\) \\(\\mathrm{Bu_4NFP_6}\\) and \\(2.0\\mathrm{mM}\\) sample: a, \\(\\mathrm{Au(BZI)(TMCz)}\\) ; b, 1a; c, DIPEA. Grey lines are signals recorded for an Ar-saturated DMSO containing \\(0.10\\mathrm{M}\\) \\(\\mathrm{Bu_4NFP_6}\\) blank. Conditions: a glassy carbon disc and a Pt wire as the working and counter electrodes, respectively. An \\(\\mathrm{Ag / AgNO_3}\\) pseudo reference electrode. Scan rate \\(= 0.10\\mathrm{V}\\mathrm{s}^{-1}\\) for CV and \\(4\\mathrm{mV}\\mathrm{s}^{-1}\\) for DPV. The electrochemical potentials were corrected using a \\(\\mathrm{Fc^{+} / Fc}\\) redox couple as an external standard.",
+    "bbox": [
+      [
+        115,
+        90,
+        876,
+        293
+      ]
+    ],
+    "page_idx": 28
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_8.jpg",
+    "caption": "Reaction scale: 1 (0.5 mmol) and 2 (5.0 mmol). \\(^b\\) Isolated yields, except \\(^1\\mathrm{H}\\) NMR yields for 3da and 3ea due to purification challenges from the protodebrominated products.",
+    "bbox": [
+      [
+        115,
+        140,
+        870,
+        430
+      ]
+    ],
+    "page_idx": 29
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Figure 1. Photoredoxcatalytic C(Ar)-C(Ar) cross-coupling reactions. a,b, Previous (a) and our (b) methods for photocatalytic C(Ar)-C(Ar) cross-coupling reactions. c, Comparisons of excited-state lifetime and excited-state oxidation potentials of representative photocatalysts and Au(BZI)(TMCz). Shown at the bottom are chemical reducing agents. Refer to Supplementary Tables 1 and 2 for the values. d, UV–Vis absorption spectrum of Au(BZI)(TMCz) recorded in toluene at 298 K. Inset figures denote the hole and electron distributions calculated for the singlet transition of the triplet geometry of Au(BZI)(TMCz) with exclusive ligand-to-ligand charge transfer (LLCT) transition character.",
+    "bbox": [],
+    "page_idx": 30
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_9.jpg",
+    "caption": "Scheme 1. Catalysis cycle. Plausible mechanism of the photoredox catalytic C–C cross-coupling reaction.",
+    "bbox": [
+      [
+        120,
+        88,
+        880,
+        425
+      ]
+    ],
+    "page_idx": 31
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_10.jpg",
+    "caption": "aReaction scale : 1a (0.05 mmol) and 2a (0.5 mmol). bYields were determined by \\(^1\\mathrm {H}\\) NMR spectroscopy using bromoform as the internal standard. \\(^{c}24\\) h reaction time",
+    "bbox": [
+      [
+        175,
+        88,
+        816,
+        640
+      ]
+    ],
+    "page_idx": 31
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "10. Figure 1, caption: it indicates the concentration of Au(BZI)(TMCz) used for the UV-Vis spectrum. Unless these complexes aggregate at higher concentrations, there's no need to include the concentration of the sample here, since the y-axis reports molar absorptivity.",
+    "bbox": [
+      [
+        163,
+        664,
+        833,
+        797
+      ]
+    ],
+    "page_idx": 32
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_7.jpg",
+    "caption": "Figure 3. Electron transfer. a,b, Heat maps showing nanosecond photoinduced transient Vis–NIR absorption difference signals of Ar-saturated DMSO containing \\(100 \\mu \\mathrm{M} \\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})\\) recorded in the absence (a) and presence (b) of \\(200 \\mathrm{mM} 1 \\mathrm{a}\\) , recorded after \\(355 \\mathrm{nm}\\) pulsed laser photoexcitation. c, Topmost panel, selected photoinduced transient Vis–NIR absorption difference spectra of Ar-saturated DMSO containing \\(100 \\mu \\mathrm{M} \\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})\\) ; second panel, selected photoinduced transient Vis–NIR absorption difference spectra of Ar-saturated DMSO containing \\(100 \\mu \\mathrm{M} \\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})\\) recorded in the presence of \\(200 \\mathrm{mM} 1 \\mathrm{a}\\) ; third panel, Vis–NIR absorption difference spectra of \\(2.0 \\mathrm{mM} \\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})\\) recorded under an anodic potential of \\(0.45 \\mathrm{V} \\mathrm{vs} \\mathrm{Ag}^{+ / 0}\\) (conditions: Pt mesh working electrode, Pt coil counter electrode, \\(\\mathrm{Ag / AgNO_3}\\) pseudo-reference electrode, and Ar-saturated DMSO containing \\(0.10 \\mathrm{M} \\mathrm{Bu}_4 \\mathrm{NPF}_6\\) and the \\(\\mathrm{Au(I)}\\) complex); fourth panel, the absorption spectrum simulated for \\(\\mathrm{[Au(BZI)(TMCz)]^{+}}\\) (CAM-B3LYP and LANL2DZ basis sets for Au and \\(6 - 311 + \\mathrm{g}(\\mathrm{d},\\mathrm{p})\\) basis set for the other atoms), where the vertical bars indicate oscillator strengths; bottom-most panel, photoluminescence spectrum of Ar-saturated DMSO containing \\(10 \\mu \\mathrm{M} \\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})\\) . d, Temporal changes of the \\(870 \\mathrm{nm} \\mathrm{[Au(BZI)(TMCz)]^{+}}\\) traces. e, Second-order kinetics analysis for charge recombination between \\(\\mathrm{[Au(BZI)(TMCz)]^{+}}\\) and \\(1 \\mathrm{a}^+\\) . See Supplementary Fig. 7 for the results for the other substrates. f, Decay traces recorded at \\(870 \\mathrm{nm}\\) in the presence of \\(50 \\mathrm{mM} 1 \\mathrm{a}\\) and increased concentrations of \\(2 \\mathrm{a}\\) (0–300 mM). g, Pseudo-first-order kinetics analysis for the catalyst recovery through electron transfer to \\(\\mathrm{[Au(BZI)(TMCz)]^{+}}\\) . See Supplementary Fig. 9 for the results for the other substrates.",
+    "bbox": [
+      [
+        118,
+        234,
+        875,
+        515
+      ]
+    ],
+    "page_idx": 33
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_5.jpg",
+    "caption": "Supplementary Fig. 5 Stern-Volmer Analysis. Plot of \\(I_0 / I\\) as a function of molar concentration of 1a.",
+    "bbox": [
+      [
+        348,
+        113,
+        620,
+        330
+      ]
+    ],
+    "page_idx": 33
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_7.jpg",
+    "caption": "Supplementary Fig. 7 Charge recombination. a–d, Second-order kinetics analysis for charge recombination between [Au(BZI)(TMCz)]\\*\\* and the substrate radical anion: a, 4-trifluoromethylphenyl bromide; b, 4-trifluoromethylphenyl iodide; c, 2-chlorquinoline; d, 3-bromoquinoline. The 870 nm photoinduced absorption kinetic traces were recorded for 100 μM Au(BZI)(TMCz) and 50 mM substrate, recorded after 355 nm pulsed laser photoexcitation (Ar-saturated DMSO).",
+    "bbox": [
+      [
+        160,
+        95,
+        835,
+        640
+      ]
+    ],
+    "page_idx": 34
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_9.jpg",
+    "caption": "Supplementary Fig. 9 Catalyst recovery. a–d, Pseudo-first-order kinetics analysis for the recovery of Au(BZI)(TMCz) through electron transfer from the radical adduct of 2a and the aryl halide to [Au(BZI)(TMCz)]<sup>++</sup>: a, 50 mM trifluoromethylphenyl bromide and 0–300 mM 2a; b, 50 mM trifluoromethylphenyl iodide and 0–300 mM 2a; c, 50 mM 2-chloroquinoline and 0–250 mM 2a; d, 50 mM 3-boromoquinoline and 0–300 mM 2a.",
+    "bbox": [
+      [
+        160,
+        95,
+        833,
+        579
+      ]
+    ],
+    "page_idx": 36
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Figure 2. Oxidative quenching. a, Photoluminescence ( \\(\\lambda_{\\mathrm{ex}} = 380 \\mathrm{nm}\\) ) spectra of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M}[\\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})]\\) recorded with increased concentration of 1a (0–100 mM). The peak marked with an asterisk (\\*) is the Raman signal of the solvent. b, Photoluminescence decay traces of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M}[\\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})]\\) recorded with increased concentration of 1a (0–40 mM) at a wavelength of \\(540 \\mathrm{nm}\\) after picosecond pulsed laser photoexcitation of \\(377 \\mathrm{nm}\\) (pulse duration = 0.2 ns). c, Corresponding pseudo first-order kinetics analysis of the quenching rate as a function of added 1a. The quenching rate is calculated with the relationship rate = \\(1 / \\tau - 1 / \\tau_0\\) , where \\(\\tau\\) and \\(\\tau_0\\) are the observed photoluminescence lifetime of \\(50 \\mu \\mathrm{M}[\\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})]\\) in the presence and absence, respectively, of 1a. d, Photoluminescence ( \\(\\lambda_{\\mathrm{ex}} = 380 \\mathrm{nm}\\) ) spectra of Ar-saturated DMSO containing \\(50 \\mu \\mathrm{M}[\\mathrm{Au}(\\mathrm{BZI})(\\mathrm{TMCz})]\\) recorded with increased concentration of DIPEA (0–500 mM).",
+    "bbox": [
+      [
+        213,
+        88,
+        784,
+        525
+      ]
+    ],
+    "page_idx": 36
+  }
+]

04d582b40fff4ca72ea92fb6489e1caf504d7821023ce030e4a5dc7af0ffe859/peer_review/images_list.json

@@ -0,0 +1,184 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure S1",
+    "bbox": [],
+    "page_idx": 7
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5.jpg",
+    "caption": "Figure 5 DPYD andTYMP are required for GSCs proliferation and self-renewal",
+    "bbox": [],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure S7. The IDH Status of Glioma could influence Immune and Metabolic Proteome",
+    "bbox": [
+      [
+        163,
+        120,
+        810,
+        833
+      ]
+    ],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "Figure 3 Proteomic Metabolism and Immune Subtypes of Glioma Could Predict Clinical Outcomes",
+    "bbox": [
+      [
+        172,
+        110,
+        850,
+        670
+      ]
+    ],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure S7. The IDH Status of Glioma could influence Immune and Metabolic Proteome",
+    "bbox": [
+      [
+        165,
+        123,
+        808,
+        831
+      ]
+    ],
+    "page_idx": 15
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5.jpg",
+    "caption": "Figure 5 DPYD andTYMP are required for GSCs proliferation and self-renewal",
+    "bbox": [
+      [
+        150,
+        120,
+        850,
+        844
+      ]
+    ],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure S7. The IDH Status of Glioma could influence Immune and Metabolic Proteome",
+    "bbox": [],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "Figure 3 Proteomic Metabolism and Immune Subtypes of Glioma Could Predict Clinical Outcomes",
+    "bbox": [
+      [
+        170,
+        168,
+        848,
+        722
+      ]
+    ],
+    "page_idx": 17
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Figure S7",
+    "bbox": [
+      [
+        165,
+        125,
+        805,
+        830
+      ]
+    ],
+    "page_idx": 17
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Figure 2 Proteomic Features Vary among Glioma Clinical Classifications",
+    "bbox": [],
+    "page_idx": 19
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Figure S7",
+    "bbox": [],
+    "page_idx": 23
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5B.jpg",
+    "caption": "Figure 5B. DPYD mRNA levels and protein levels in T4121 and Mes28 cells after knocking-down shows the efficiency higher than \\(50\\%\\) (Student's-t test, \\(\\mathrm{p}< 0.0001\\) ).",
+    "bbox": [
+      [
+        160,
+        191,
+        816,
+        494
+      ]
+    ],
+    "page_idx": 25
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5F.jpg",
+    "caption": "Legend: Figure 5F. The phospho- H2A positive cell percentage is calculated, indicating increased DNA damage after DYPD knockdown (Student's-t test).",
+    "bbox": [
+      [
+        150,
+        90,
+        846,
+        355
+      ]
+    ],
+    "page_idx": 27
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_6.jpg",
+    "caption": "Figure S7",
+    "bbox": [
+      [
+        163,
+        125,
+        803,
+        832
+      ]
+    ],
+    "page_idx": 30
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5K.jpg",
+    "caption": "Figure 5K",
+    "bbox": [
+      [
+        147,
+        316,
+        750,
+        838
+      ]
+    ],
+    "page_idx": 32
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_4A.jpg",
+    "caption": "Figure 4A",
+    "bbox": [],
+    "page_idx": 35
+  }
+]

04e54a8171b4bd17627f1b2f4f9f0027e3a20ca26ff9e5bfcbb8c21daeee608b/peer_review/images_list.json

@@ -0,0 +1,205 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. 1 c XRD patterns of NGA-COF synthesized and simulated.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1d.jpg",
+    "caption": "Fig. 1d Nitrogen adsorption-desorption isotherms of NGA-COF with corresponding pore size distribution inset.",
+    "bbox": [
+      [
+        147,
+        88,
+        528,
+        315
+      ]
+    ],
+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_2.jpg",
+    "caption": "Supplementary Fig. 2. Simulated pore size of NGA-COF.",
+    "bbox": [
+      [
+        148,
+        406,
+        629,
+        628
+      ]
+    ],
+    "page_idx": 7
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3c.jpg",
+    "caption": "Fig. 3c \\(k^2\\) -weighted FT-EXAFS spectra of Pt-foil, NGA-COF@Pt and PtO2.",
+    "bbox": [],
+    "page_idx": 7
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3e.jpg",
+    "caption": "Fig. 3e Corresponding EXAFS R space fitting curve of NGA-COF@Pt (Inset: Simulations models of NGA-COF@Pt).",
+    "bbox": [
+      [
+        150,
+        504,
+        525,
+        723
+      ]
+    ],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_4e.jpg",
+    "caption": "Fig. 4e High-resolution XPS spectra of \\(N\\) 1s of different samples.",
+    "bbox": [],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_6d.jpg",
+    "caption": "Fig. 6d Zeta potential of NGA-COF and NGA-COF@Pt at different pH values.",
+    "bbox": [],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_7b.jpg",
+    "caption": "Fig. 7b (old version) Schematic illustration of H intermediates adsorbed on the Pt site of NGA-COF@Pt-2H, which is easy to desorb. DEMS measurements of \\(H_{2}\\) , DH and \\(D_{2}\\) signals from the reaction products for D-labeled.",
+    "bbox": [],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_7.jpg",
+    "caption": "Fig. 7 Schematic illustration and corresponding free energy diagram of HER over Pt site of a Pt (111) and b NGA-COF@Pt before and after optimizing by H\\* intermediates.",
+    "bbox": [
+      [
+        148,
+        208,
+        840,
+        445
+      ]
+    ],
+    "page_idx": 11
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_16.jpg",
+    "caption": "Supplementary Fig. 16. a-d SEM images and e-f TEM images at different magnifications of NGA-COF@Pt after chronopotentiometric test in 0.5 M \\(H_{2}SO_{4}\\) .",
+    "bbox": [],
+    "page_idx": 11
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5e.jpg",
+    "caption": "Fig. 5e In-situ Raman spectra of NGA-COF@Pt at various potentials. Electrolyte: 0.5 \\(M H_{2}SO_{4}\\) .",
+    "bbox": [],
+    "page_idx": 14
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_6.jpg",
+    "caption": "Supplementary Fig. 6. a Magnified atomic-resolution HAADF-STEM image of NGA-COF@Pt. b Enlarged atomic-resolution HAADF-STEM image of NGA-COF@Pt and c corresponding distance between two bright spots (Pt atoms) in the red box. d Simulated distance between two adjacent Pt atoms in NGA-COF@Pt.",
+    "bbox": [],
+    "page_idx": 14
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Additional aberration-corrected HAADF-STEM images of NGA-COF@Pt.",
+    "bbox": [
+      [
+        147,
+        92,
+        722,
+        630
+      ]
+    ],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_3.jpg",
+    "caption": "Supplementary Fig. 3. a-c SEM images of \\(\\mathrm{TiO2NTs}\\) .",
+    "bbox": [
+      [
+        153,
+        758,
+        848,
+        873
+      ]
+    ],
+    "page_idx": 17
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1a.jpg",
+    "caption": "Fig. 1a Schematic illustration of the synthesis of NGA-COF.",
+    "bbox": [
+      [
+        148,
+        199,
+        850,
+        350
+      ]
+    ],
+    "page_idx": 18
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2d.jpg",
+    "caption": "Fig. 2d EDS mappings of NGA-COF@Pt and commercial 20 wt.% PtC for Pt elements. The alignment issue in Fig. 2d has been fixed according to the suggestion.",
+    "bbox": [
+      [
+        149,
+        202,
+        722,
+        483
+      ]
+    ],
+    "page_idx": 20
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1d.jpg",
+    "caption": "Fig. 1d. Nitrogen adsorption–desorption isotherms of NGA-COF with corresponding pore size distribution inset.",
+    "bbox": [],
+    "page_idx": 20
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_37.jpg",
+    "caption": "Supplementary Fig. 37. Calculated TDOS of NGA-COF and NGA-COF@Pt.",
+    "bbox": [
+      [
+        171,
+        280,
+        525,
+        499
+      ]
+    ],
+    "page_idx": 20
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5d.jpg",
+    "caption": "Fig. 5d EIS of different samples. Electrolyte: \\(0.5 \\text{M} \\text{H}_2\\text{SO}_4\\)",
+    "bbox": [
+      [
+        150,
+        545,
+        525,
+        772
+      ]
+    ],
+    "page_idx": 21
+  }
+]

050529daf1daf78ef8cedaf4674a0be73a105c7021e9dcbcfb5618448dc10399/peer_review/images_list.json

@@ -0,0 +1,44 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure S1. (a) The four 3-fold axes of the cubic symmetry. (b) Orientations of the FA molecule such that its molecular dipole satisfies the 3-fold symmetry within the PbI \\(_6\\) cage. I, Pb, C, N, and H are shown in violet, white octahedra, brown, light blue, and pink, respectively.",
+    "bbox": [
+      [
+        130,
+        98,
+        872,
+        355
+      ]
+    ],
+    "page_idx": 12
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Figure S3. Zoom on the final FAPbI3 structures starting from all-aligned (a) and pseudo-random (b) FA configurations after vc-relax. The Pb-I distances for two adjacent octahedra are highlighted. The typical \\(- \\theta /\\theta\\) tilting pattern of the octahedra can be seen in the pseudo-random case, while the all-aligned case shows a non-physical collective I-shift resulting in a tilting angle of \\(\\theta\\) for all octahedra. The reference system for the tilt angle and the tilting angles are shown in red. The color code is the same as in Fig.1.",
+    "bbox": [
+      [
+        130,
+        81,
+        865,
+        327
+      ]
+    ],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure S4. Comparison of the total energy per unit cell between the all-aligned and pseudo-randomly oriented FA configurations for different supercells. On the x-axis, the number of atoms in the supercell and the k-point grid (e.g., \\(\\mathrm{k1 = 1 \\times 1 \\times 1}\\) k-point grid) are given. The all-aligned FA configurations (gray) are always higher in energy (less stable) and are set to \\(0 \\mathrm{eV}\\) for each supercell. The energies of the pseudo-randomly oriented FA configurations (blue) are given with respect to the corresponding value of the all-aligned ones.",
+    "bbox": [
+      [
+        267,
+        323,
+        725,
+        590
+      ]
+    ],
+    "page_idx": 17
+  }
+]

05076b04f05611927d832f0da3d4ffa4dcfd58c6fd3c8e741c288ede24fc3e8e/peer_review/images_list.json

@@ -0,0 +1,23 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R1 Long-term stability of the CEP-SERS patch in \\(50\\mathrm{mM}\\) NaCl solution measured by SERS intensity of \\(1\\mu \\mathrm{M}\\) R6G.",
+    "bbox": [],
+    "page_idx": 2
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure R2 (a) Measured SERS Spectra of pH 4 buffer solution (blue), 1 μM R6G in the buffer solution (magenta), and 1 μM R6G after 1 hour immersion in the buffer solution (red). (b) pH stability of CEP-SERS patch under varying pH environment and (c) under varying immersion duration in pH 4 buffer solution evaluated by 1 μM R6G SERS intensity measurement at 1365 cm-1.",
+    "bbox": [
+      [
+        186,
+        466,
+        814,
+        628
+      ]
+    ],
+    "page_idx": 3
+  }
+]

051d508d2527ceb90efdf6ed26b621b83537910322d956a72866bd26be024ca3/peer_review/images_list.json

@@ -0,0 +1 @@
+[]

05225d17b4449ec0559648b67741e3748a3e400b9813ff34e06b11744539c34d/peer_review/images_list.json

@@ -0,0 +1,72 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig. R1. Comparing geographical patterns of SST over the two warming phases. Panels A, B, D and E use the same colour scale, highlighting how cooler habitats disappeared from the region over time. Panels C and F use the same colour scale, highlighting how mean warming may have been greatest in northern regions (note that panel C does not capture rapid warming over the stage boundary at this temporal resolution). These (sub)zones cover the range of temperature values of the main \\(\\mathrm{CO_2}\\) scenario, from Spinatum at 400 ppm to Exaratum at 1000 ppm (see Table 2 and global maps, Fig. S8, for additional scenarios). For comparison with Fig. 1, these show the Toarcian paleogeography (i.e. maximum sea-level coastlines for the study interval). The coverage of occurrences per (sub)zone is shown (A, B, D, E only) using the same colouration as Fig. 1.",
+    "bbox": [
+      [
+        115,
+        90,
+        925,
+        644
+      ]
+    ],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Fig. R2. Boxplots of modelled seawater temperatures (SST) at regional sampled occurrences, rather than over the entire coverage of the region. This highlights how sampling can exacerbate or compensate for modelled changes in regional temperature, resulting in observed changes slightly different to the original modelled changes (via CLIMBER-X). Panels are the region names plotted approximately according to paleocoordinates, with N, E and W being abbreviations of north, east and west. X-axis labels are abbreviations of the ammonite (sub)zones, through Margaritatus, Spinatum, Tenuicostatum, Exaratum, Falciferum, and Bifrons.",
+    "bbox": [
+      [
+        115,
+        92,
+        840,
+        610
+      ]
+    ],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Fig. R3. Boxplots of regional sampled occurrences paleolatitudes (plat) in the Toarcian (Toa). Assuming higher latitudes are cooler and lower latitudes are warmer, this highlights how sampling can exacerbate or compensate for modelled changes in regional temperature. Some of the observed temperature changes in Fig. R2 are likely because of changes in sampling paleolatitude, rather than changes in modelled regional temperature. See Fig. R2 for further details.",
+    "bbox": [
+      [
+        120,
+        99,
+        830,
+        545
+      ]
+    ],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure R4. Sea surface temperature estimates (in \\(^\\circ \\mathrm{C}\\) , scale bar on right) of the 400 ppm \\(\\mathrm{CO_2}\\) scenario with the Toarcian paleogeography (180 Ma), showing the original CLIMBER-X output (top panel), the data downscaled by nearest neighbour values (middle), and the data downscaled by bilinear interpolation (lower). Downscaling is to the same resolution as the HadCM3 model, which is quantitatively demonstrated to produce similar temperature features as the CLIMBER-X model.",
+    "bbox": [
+      [
+        123,
+        92,
+        820,
+        555
+      ]
+    ],
+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure R5. Sea surface temperature estimates (in \\(^\\circ \\mathrm{C}\\) , scale bar on right) of the 1000ppm \\(\\mathrm{CO_2}\\) scenario with the Toarcian paleogeography (180 Ma). Further details as in Fig. R4.",
+    "bbox": [
+      [
+        125,
+        92,
+        822,
+        558
+      ]
+    ],
+    "page_idx": 14
+  }
+]

055c635ef5ff7a481cce5739a3e68be679d4efd18c3744431eaf8e18a25f3f77/peer_review/images_list.json

@@ -0,0 +1,16 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig 1. Containers used for Oxitec V 2.0 fsRIDL egg releases in Florida (2021). Eggs are hatched in water and males fly out of the holes. A similar container can be used for pgSIT - requiring the males to FLY out - preventing any surviving flightless females (most die on the surface of the water due to lack of flight) from even entering the environment.",
+    "bbox": [
+      [
+        115,
+        144,
+        880,
+        540
+      ]
+    ],
+    "page_idx": 15
+  }
+]

057e2e27efee7373cf5b78cfff39555b737e598a4088a3ff490826cd25e121be/peer_review/images_list.json

@@ -0,0 +1 @@
+[]

059a54d253ab5af79d48ff1a3f02886f0511ffb2444cb09d7b8ed598ea46c8cb/peer_review/images_list.json

@@ -0,0 +1,37 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "I appreciate the careful analysis and testing of both N and C tagging, but I would simplify figure 3 and make it smaller. I have three suggestions:",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5a.jpg",
+    "caption": "In Figure 5a, I have problems seeing the path for the DNA. The figure might suffer from the PDF conversion, but also, the electrostatic surface potential makes it challenging to see.",
+    "bbox": [],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Fig 1. While I have no concerns with the conclusions presented by the authors, the layout of the cropped gels in Fig 1 are somewhat disorienting – specifically when the width of the gels differs in a single panel (e.g. panel b). Additionally, the cropping of the final two gels in panel e appears to be a bit aggressive. The full gels included as source data provide essential and reassuring context. I don’t have specific suggestions for how to improve the figure, but I encourage the authors to consider adjustments to improve readability.",
+    "bbox": [],
+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_4.jpg",
+    "caption": "New Supplementary Figure 4:",
+    "bbox": [
+      [
+        113,
+        78,
+        875,
+        853
+      ]
+    ],
+    "page_idx": 10
+  }
+]

05bf643a9d532f9bf0fa15baf0d9ab972ffa3fc6f3d979b4a60cf0f537b0972d/peer_review/images_list.json

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+[]

05cdd05c8033f50c5d58d58f81996f649b1fce4c208692e95be55fcdb4c8a5aa/peer_review/images_list.json

@@ -0,0 +1,23 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Figure 2. The developmental changes of cortical MI and HFO at given lobes. a \\(\\mathrm{MI}^{80\\mathrm{Hz}}\\) & 0.5-1 Hz denotes the strength of coupling between the amplitude of \\(\\mathrm{HFO}^{80\\mathrm{Hz}}\\) and the phase of slow-wave0.5-1 Hz, as rated by modulation index. b Occurrence rate (/min) of \\(\\mathrm{HFO}_{\\mathrm{HIL}}^{80\\mathrm{Hz}}\\) as defined by the Hilbert method. In each violin plot, a regression line is provided based on a model incorporating the square root of age ( \\(\\sqrt{\\mathrm{age}}\\) ) as an independent variable. The white circle within each violin plot represents the median.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Figure 2. The developmental changes of cortical MI and HFO at given lobes. a \\(\\mathrm{MI}_{\\geq 80\\mathrm{Hz}}\\) & 0.5-1 \\(\\mathrm{Hz}\\) denotes the strength of coupling between the amplitude of \\(\\mathrm{HFO}_{\\geq 80\\mathrm{Hz}}\\) and the phase of slow-wave0.5-1 \\(\\mathrm{Hz}\\) , as rated by modulation index. b Occurrence rate (/min) of \\(\\mathrm{HFO}_{\\mathrm{HIL}_{\\geq 80\\mathrm{Hz}}}\\) as defined by the Hilbert method. In each violin plot, a regression line is provided based on a model incorporating the square root of age ( \\(\\sqrt{\\mathrm{age}}\\) ) as an independent variable. The white circle within each violin plot represents the median.",
+    "bbox": [],
+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5.jpg",
+    "caption": "Figure 5. Dynamic tractography. The video snapshots present the varying intensity of a co-growth of \\(\\mathrm{MI} \\geq 80 \\mathrm{~Hz}\\) & \\(0.5 - 1 \\mathrm{~Hz}\\) and \\(\\mathbf{b}\\) co-diminution of HFOHIL \\(\\geq 80 \\mathrm{~Hz}\\) at ages 1, 5, 10, and 20 years, as estimated by univariate regression analysis incorporating 'lage as an independent variable. Supplementary Movies 4-5 show the data across generations from 1 to 21 years. The brain images in this figure were created using FreeSurfer (https://surfer.nmr.mgh.harvard.edu/fswiki/CorticalParcellation).",
+    "bbox": [],
+    "page_idx": 14
+  }
+]

05d4b9f2850394e9266c31450e9dda48f8747cd9d03b3709c218ddce72f9a01d/peer_review/images_list.json

@@ -0,0 +1,9 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Dash lines represent intramolecular H-bonding",
+    "bbox": [],
+    "page_idx": 0
+  }
+]

064d527fad7716c8fc035b281d94ad0c0f3efc69fc8d0100b12f56fb6a277f4e/peer_review/images_list.json

@@ -0,0 +1,86 @@
+[
+  {
+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Rebuttal Figure 1. Volcano plots summarising results of RNAseq performed on whole skin from ears and tails of affected Ikkb<sup>mut/mut</sup> and Ikkb<sup>WT</sup> mice. Genes implicated in psoriasis (S100a8, S100a9, Defb4, Tnf, Il36a, Il36g, Nos2, Ccl20, Ccl2, Il1B, Cxcl9, Il23a) are labelled. Th2-related genes that have been noted in AD are also shown as they are either downregulated (Il34) or not significantly different (Ccl24, Ccr4, Ccl17).",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Rebuttal Figure 2. Analysis of \\(\\mathrm{CD4 + }\\) T cells recovered from ears, tail and back skin.",
+    "bbox": [
+      [
+        123,
+        98,
+        868,
+        227
+      ]
+    ],
+    "page_idx": 5
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "Rebuttal Figure 3. Sorted naive T cells (CD4+ CD4+ CD62L+ GFP-cells) from \\(Ikkb^{WT}x\\) \\(Foxp3^{\\mathrm{GFP}}\\) (top panel) or \\(Ikkb^{mut / mut}x\\) \\(Foxp3^{\\mathrm{GFP}}\\) mice (lower panel) were injected intravenously into \\(Rag1^{- / - }\\) recipient mice (n=3 per genotype). At 8 weeks post-transfer, blood was collected from each mouse and analysed by flow cytometry. Donor CD4+ T cells are shown in Q1 and those that have upregulated Foxp3 (GFP) are shown in Q2.",
+    "bbox": [
+      [
+        137,
+        93,
+        753,
+        263
+      ]
+    ],
+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_4.jpg",
+    "caption": "Rebuttal Figure 4. Tregs (GFP+) and conventional T cells (GFP-) were isolated from \\(Ikkb^{mut / mut}x\\) \\(Foxp3^{\\mathrm{GFP}}\\) mice, stimulated in vitro with anti-CD3+antiCD28, then harvested and analysed on day 3 for GFP expression.",
+    "bbox": [
+      [
+        123,
+        479,
+        707,
+        737
+      ]
+    ],
+    "page_idx": 7
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_6.jpg",
+    "caption": "Rebuttal Figure 6. Appearance of back skin from mice of indicated genotypes.",
+    "bbox": [],
+    "page_idx": 7
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_7.jpg",
+    "caption": "Rebuttal Figure 7. Quantification of Foxp3+ cells from lesional skin",
+    "bbox": [
+      [
+        120,
+        533,
+        870,
+        690
+      ]
+    ],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_8.jpg",
+    "caption": "Rebuttal Figure 8. Analysis of cell-intrinsic action of IKK2 by construction of mixed bone marrow chimeras. Irradiated \\(Rag1^{-/ - }\\) mice were reconstituted with 50:50 mixtures of CD45-allotype marked donor bone marrow from \\(Ikbk^{WT}\\) , \\(Ikbk^{b/mut}\\) or \\(Ikbk^{b/mut/mut}\\) mice. Foxp3+ Tregs were analysed 8 weeks after reconstitution according to allotype of donor origin. Results are pooled from two identical experiments.",
+    "bbox": [
+      [
+        128,
+        90,
+        699,
+        280
+      ]
+    ],
+    "page_idx": 10
+  }
+]

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+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Bone mineral density",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Hip fracture",
+    "bbox": [
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+        113,
+        803,
+        430
+      ]
+    ],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Coronary artery disease",
+    "bbox": [
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+        426,
+        868
+      ]
+    ],
+    "page_idx": 19
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Type 2 diabetes",
+    "bbox": [
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+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R1. Comparison of colonines from stlP-overexpressed and complemented strains. (A) Colonies of the wild-type strain (M145), M145 overexpressing StlP (M145+pXZ15), and the complemented stlP mutants created by transposon mutagenesis (ΔstlP+pXZ15) or gene replacement (ΔstlPFL+pXZ15). All strains contain plasmid pXZ15, which expresses stlP from constitutive gapAp promoter. For each strain, approximately 100 spores were plated on LPMA plate and incubated 5 days at 30 °C before imaging. (B) Quantitative assessment of colony diameters. The average diameters are: 3.8±0.6 mm (M145), 2.5±0.5 mm (ΔstlP+pXZ15), 2.5±0.2 mm (ΔstlPFL+pXZ15), and 3.35±0.38 mm (M145+pXZ15). Please note that the colony size of wild-type strain is significantly reduced by overexpression of StlP. Error bars represent the standard error of the mean (*, 0.01<P<0.05).",
+    "bbox": [],
+    "page_idx": 7
+  }
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+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "Figure 1: Possible mechanisms of cancer development in psoriasis patients",
+    "bbox": [],
+    "page_idx": 0
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+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R1. Collective movement of UrNMs in \\(200~\\mathrm{mM}\\) urea that is dispersed in acetate buffer. (a) A time-lapse sequence of images that show the collective movement of UrNMs in \\(200~\\mathrm{mM}\\) urea in acetate buffer. (b) Velocity analysis of UrNMs particulate in PBS buffer and in acetate buffer. The significant difference is analyzed by student's t-test: \\(^{**}\\mathrm{P}< 0.01\\) . \\(\\mathrm{N} = 5\\) .",
+    "bbox": [
+      [
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+        201,
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+    ],
+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure R2b. Trajectory tracking of the UrNMs in collective movement. (b) and (f) depict one-second-long trajectories during a spreading stage. (c) and (g) show one-second-long trajectories during a sinking stage. (d) and (e) display four-second-long trajectories during a swirling stage in urea. The blue and green color-coded trajectories indicate counterclockwise and clockwise directions of UrNMs on the left and right sides of the chamber, respectively. \\(N = 15\\) .",
+    "bbox": [
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+        551
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+    ],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure R4. Enzymatic activity of UrNMs after treatment in simulated urine or urine from mice for 30 min. (a) The real-time UV-vis light absorbance of phenol red solutions containing 200 mM urea and treated UrNMs. In the control group, the UrNMs were mixed with PBS solution. (b) The specific enzymatic activity of UrNMs after treatment. Significant difference is analyzed by students' t-test: \\(\\star \\star \\star = \\mathsf{P} < 0.001\\) ; ns = not significant \\((P > 0.05)\\) . \\(\\mathsf{N} = 3\\)",
+    "bbox": [],
+    "page_idx": 16
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure R6. Convective dynamics of CatNMs. A time-lapse sequence of images that show the directional and collective movement of CatNMs in \\(100mM\\mathsf{H}_2\\mathsf{O}_2\\) . Scale bar: \\(4mm\\) .",
+    "bbox": [],
+    "page_idx": 24
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Fig. R1 Collective motion of UrNMs/MSNPs indicated by colour change. A time-lapse sequence of images shows the directional and collective movement of (a) UrNMs in urea with phenol red and (b) MSNPs in urea with phenol red. Scale bar: 4 mm.",
+    "bbox": [
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+    "page_idx": 25
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Fig. R2 Motion analysis of UrNMs in urea with varying NaCl concentrations. (a) Mean square displacement (MSD) of UrNMs in \\(50~\\mathrm{mM}\\) urea solutions with different NaCl concentrations (0.05, 0.5, 5, 25 and \\(50~\\mathrm{mM}\\) ), analyzed by tracking 20 particles. (b) The diffusion coefficient of the nanomotors at each condition was determined. Ionic self-diffusiophoresis is a plausible explanation, as the ionic species have different diffusivities. These differences between the cations and anions lead to the generation of local electric fields and double-layer polarization around the particle, initiating its motion. Consequently, increasing the ionic strength in the medium inhibits the formation of a concentration gradient, thereby reducing the self-propulsion of the nanomotors.",
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+        145,
+        857,
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+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Fig. R1. The schematic drawing of enhanced repulsive force between \\*OOH and \\(\\mathrm{N_4}\\) .",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Fig. R2. ORR polarization curves in 0.1 M KOH before and after the addition of 1 mM SCN⁻.",
+    "bbox": [
+      [
+        277,
+        92,
+        695,
+        330
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+    ],
+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Fig. R3. (a) Fourier transformation of EXAFS spectra of CoPc, Co foil, CoPc-O-COF, and CoPc-S-COF. (b) The EXAFS fitting results of CoPc-O-COF, CoPc-S-COF and CoPc.",
+    "bbox": [
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+    ],
+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Fig. R4. Co K-edge XANES spectra of CoPc, CoPc-O-COF, CoPc-S-COF, and Co foil.",
+    "bbox": [
+      [
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+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Fig. R5. (a) The visualized scheme of the uniform conjugated system of CoPc-S-COF (top) and CoPc-O-COF (bottom). The schematic diagram of the uniform conjugated system in top/side/bottom view for (b) CoPc-S-COF and (c) CoPc-O-COF.",
+    "bbox": [
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+    "page_idx": 9
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Fig. R6 Pore volume and pore size distribution of (a) CoPc-O-COF and (b) CoPc-S-COF.",
+    "bbox": [
+      [
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+    "page_idx": 11
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_6.jpg",
+    "caption": "Fig. R7 Tafel plots of CoPc-O-COF, CoPc-S-COF, and CoPcF16.",
+    "bbox": [
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+    "page_idx": 12
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_7.jpg",
+    "caption": "Fig. R8 Mass activity of CoPc-O-COF and CoPc-S-COF.",
+    "bbox": [
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+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_8.jpg",
+    "caption": "Fig. R9 ORR polarization curves in \\(0.1\\mathrm{M}\\) KOH before and after the addition of 1 and \\(25\\mathrm{mM}\\) SCN-",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_9.jpg",
+    "caption": "Fig. R10 PXRD patterns of (a) CoPc-S-COF and (b) CoPc-O-COF after immersion in different solutions.",
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+    "type": "image",
+    "img_path": "images/Figure_unknown_10.jpg",
+    "caption": "Fig. R1. (a) LSVs of CoPc-S-COF at 1600 rpm in \\(\\mathrm{O}_2\\) -saturated 0.1 M KOH with or without salt bridge. (b) \\(\\mathrm{H}_2\\mathrm{O}_2\\) selectivity and electron transfer number \\(n\\) of CoPc-S-COF with or without salt bridge.",
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+    "type": "image",
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+    "caption": "Fig. R2. (a) Fourier transform of EXAFS spectra of CoPc, Co foil, CoPc-O-COF, and CoPc-S-COF. (b) The EXAFS fitting results of CoPc-O-COF, CoPc-S-COF and CoPc.",
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+    "type": "image",
+    "img_path": "images/Figure_unknown_12.jpg",
+    "caption": "Fig. R3. The Co \\(k^{3}\\) -weighted \\(K\\) -space spectra of CoPc-O-COF, CoPc-S-COF, and CoPc.",
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+    "caption": "Fig. R4. The Co K-edge XANES spectra of (a) CoPc-O-COF and (d) CoPc-S-COF before and after stability tests. The EXAFS fitting results of (b) CoPc-O-COF and (e) CoPc-S-COF before and after stability tests. The Co \\(k^3\\) -weighted \\(K\\) -space spectra of (c) CoPc-O-COF and (f) CoPc-S-COF before and after stability tests.",
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+    "caption": "Fig. R5. TEM and HR-TEM images of (a, b, e, f) CoPc-O-COF and (c, d, g, h) CoPc-S-COF before and after soaking into \\(3\\% \\mathrm{H}_2\\mathrm{O}_2\\) solution for three days.",
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+    "type": "image",
+    "img_path": "images/Figure_unknown_15.jpg",
+    "caption": "Fig. R6. FT-IR spectra of (a) CoPc-O-COF and (b) CoPc-S-COF before and after soaking into \\(3\\% \\mathrm{H}_2\\mathrm{O}_2\\) solution for three days.",
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+    "caption": "Fig. R7. (a) ORR polarization curves of CoPc-S-COF and CoPc-O-COF in 0.1 M KOH before and after the addition of 1, 5, and 25 mM SCN. (b) ORR polarization curves of the metal free H2PcF16 electrode as well as CoPc-S-COF and CoPc-O-COF in 0.1 M KOH.",
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+    "caption": "Fig. R8. \\(\\mathrm{H}_2\\mathrm{O}_2\\) electroproduction in flow cell with \\(1\\mathrm{M}\\mathrm{Na}_2\\mathrm{SO}_4\\) electrolyte. (a) LSV of CoPc-S-COF in flow cell. (b) The chronoamperometry measurements at varied applied voltages of CoPc-S-COF. (c) \\(\\mathrm{FE}_{\\mathrm{H}_2\\mathrm{O}_2}\\) of CoPc-S-COF at varied applied voltages. (e) \\(\\mathrm{H}_2\\mathrm{O}_2\\) yields of CoPc-S-COF under a current density of \\(100\\mathrm{mA}\\mathrm{cm}^{-2}\\) . (d) Chronopotentiometry curve at a current density of \\(100\\mathrm{mA}\\mathrm{cm}^{-2}\\) and the corresponding \\(\\mathrm{FE}_{\\mathrm{H}_2\\mathrm{O}_2}\\) in the flow cell for CoPc-S-COF.",
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+    "img_path": "images/Figure_unknown_18.jpg",
+    "caption": "Fig. R9. (a, d) Schematic synthesis of the model molecules. (b, e) Molecular and (c, f) packing structure of the model molecules in their single crystals. C, H, and S are displayed in grey, white, and yellow, respectively.",
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+    "img_path": "images/Figure_unknown_19.jpg",
+    "caption": "Fig. R10. Co L₂, 3-edge XANES spectra of CoPc-O-COF and CoPc-S-COF.",
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+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R1 Illustration of the preparation of the HS/DAC complex and HS/DAC coating.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure R2 (a) Zeta Potentials of free HS, DAC and HS/DAC complex. (b) Surface potentials of TPU films with and without coatings. (c) Molecular structures and in vitro antimicrobial properties of DA/QAC model complex with neutralizing charge.",
+    "bbox": [
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+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure R3 The water contact angles (a), ATR-FTIR spectra (b) and XPS (c) of bare films and HS/DAC coated films before and after treated with saline solution \\((n = 6)\\) . (d) Salt-triggered adaptive dissociation and its antibacterial and antithrombotic mechanism of HS/DAC coating. \\(\\mathrm{***}p< 0.001\\) .",
+    "bbox": [
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+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure R4 Agar plate colony counting assay of the blood pretreated bare films and the blood pretreated coated films, \\(\\mathrm{n} = 4\\) . \\(***p< 0.001\\) .",
+    "bbox": [
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+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Figure R5 (a) Photographs of the thrombi on the surface of samples and cross-sectional observation of the samples. (b) Quantitative analysis of samples before and after circulation \\((n = 4)\\) . \\(***p< 0.001\\) , \\(**p< 0.01\\) .",
+    "bbox": [
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+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Figure R6 Evaluation of the anti-thrombotic ability of the HS/DAC coating in vitro and in vivo. (a) Anti-FXa and (b) anti-FIIa assays of the bioactivity of heparin on the HS/DAC-coated TPU (n = 3). (c) Amounts of BSA absorbed on bare and HS/DAC-coated TPU, as determined by a BCA protein assay kit (n = 9). (d) CLSM images of Fg adhesion, activation and leukocyte adhesion on the surface of bare catheters and HS/DAC-coated catheters. (e) Schematics of the antithrombotic mechanism of HS/DAC-coated catheters. (f) Digital and SEM images of the thrombus on the bare and HS/DAC-coated CVC catheters in the acute canine model in vivo. (g) Process by which the electrostatic interaction of the HS/DAC coating dissociates and",
+    "bbox": [
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+    "page_idx": 15
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_6.jpg",
+    "caption": "Figure R7 a Colony count of the HS/DAC coatings to S. aureus and E. coli. b Antibacterial activity of the HS/DAC coatings against S. aureus and E. coli. c Zone of inhibition tests of bare and HS/DAC coated TPU films \\((n = 4)\\) . \\(***p< 0.001\\) .",
+    "bbox": [
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+    ],
+    "page_idx": 17
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_7.jpg",
+    "caption": "Figure R8 Antibiofilm activity of the coating. (a)Agar plate colony counting assay and (b) SEM images of the bare TPU and (HS/DAC)-TPU incubated with bacteria for 48 h \\(\\mathrm{(n = 3)}\\) . (c) Images of catheters and live bacteria adhering to the inner surfaces of the catheters and PVC tubes in flow conditions at different times. \\(***p< 0.001\\)",
+    "bbox": [
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+    "page_idx": 19
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_8.jpg",
+    "caption": "Figure R9 Molecular structures and in vitro antimicrobial properties of DA/QAC model complex with neutralizing charge.",
+    "bbox": [
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+    "page_idx": 20
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_9.jpg",
+    "caption": "Figure R10 a The multi-channel circulation model of long-term stability underflow. b. Thrombosis on the surface of the coating after flowing at \\(0 \\mathrm{s}^{-1}\\) , \\(30 \\mathrm{s}^{-1}\\) and \\(300 \\mathrm{s}^{-1}\\) for 30 days. c The corresponding thrombus mass changes. d The colony count of HS/DAC coating after flowing at \\(0 \\mathrm{s}^{-1}\\) , \\(30 \\mathrm{s}^{-1}\\) and \\(300 \\mathrm{s}^{-1}\\) for 30 days. e The corresponding antibacterial rate. f The staining and SEM images of the HS/DAC coating with high speed water impact. g The corresponding thrombus mass changes. h The corresponding antibacterial rate.",
+    "bbox": [
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+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_19.jpg",
+    "caption": "Supplementary Fig. 19 (a) Cell viability of bare, HS/QAC and HS/DAC-coated TPU via extraction mode \\((n = 8)\\) and contact mode \\((n = 3 - 4)\\) .",
+    "bbox": [
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+    "page_idx": 28
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_10.jpg",
+    "caption": "Figure R1 The content of S element in the extraction solution of the bare TPU and HS/DAC coated TPU \\((n = 3)\\) .",
+    "bbox": [
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+    "page_idx": 38
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_3c.jpg",
+    "caption": "Fig. 3c Amounts of BSA absorbed on bare and HS/DAC-coated TPU. The sample was immersed in BSA solution and the adsorption of proteins was determined by a BCA protein assay kit \\(\\mathrm{(n = 9)}\\) .",
+    "bbox": [
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_4i.jpg",
+    "caption": "Fig. 4i The long-term antibacterial stability of HS/DAC coating in artificial blood with shear rates of 0, 30, and \\(300 \\mathrm{~s}^{-1}\\) after 30 days of flow (n = 4).",
+    "bbox": [],
+    "page_idx": 52
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+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Fig. S1. Relationship between coupling strength and the minimum FSR in the region of gradually reduced FSR. a, Simulated minimum FSR when varying the coupling \\(\\mu\\) . The phenomenon of gradually reduced FSR happens when the coupling \\(\\mu\\) starts to become comparable with the FSR of the cavity 1. For example, when the coupling \\(\\mu\\) is small, it can only couple degenerate modes therefore provide a conventional two mode splitting with a splitting equal to \\(2\\mu\\) . When the coupling \\(\\mu\\) becomes stronger, such that \\(2\\mu\\) is larger than the FSR, dispersive coupling starts to contribute, and multi-hybrid modes are formed. We extract the coupling strength \\(\\mu\\) in",
+    "bbox": [],
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+    "type": "image",
+    "img_path": "images/Figure_1.jpg",
+    "caption": "rFig. 1. Total distance travelled during the conditioning session in the blue laser-paired chamber and during post-conditioning session in the entire arena in CPP test. No significant difference was observed in both D3-Cre and D3-Cre/ChR2 mice. \\(n = 8\\) mice per group. Data are expressed as mean \\(\\pm\\) SEM.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "rFig. 2. Orofacial grooming induced by optogenetic activation of OT D3 neurons suppresses sucrose splash-triggered body licking. Blue light (activation of D3-Cre/ChR2 neurons; 10 ms pulses, 20 Hz for 10 s) or green light (same parameters as blue light as comparison) was delivered when sucrose splash-triggered body licking occurred (n = 5 mice). Left, percent of trials in which body licking terminated. Right, percent of trials in which body licking terminated and orofacial grooming initiated. Each mouse was tested for 20 trials. Data are expressed as mean ± SEM. Wilcoxon signed-rank test. p < 0.0001 for (D) and p = 0.0005 for (E). ***p<0.001, ****p<0.0001.",
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+    "img_path": "images/Figure_4.jpg",
+    "caption": "Fig. 4. Photovoltaic performance of the PSCs based on PVSK, PVSK-HABr/CF, and PVSK-HABr/Cl₂-CF. (b) \\(J - V\\) curves measured in the reverse scan direction (1.2 to 0 V, 250 mV s⁻¹). (c) Statistical PCE. (d) Statistical \\(V_{\\text{OC}}\\).",
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+    "caption": "Entry for the Table of Contents",
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+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_24.jpg",
+    "caption": "Supplementary Fig. 24 | Photovoltaic parameters of the PVSK, HACl/CF-treated, HACl/Cl₂-CF-treated, and HABr/Cl₂-CF-treated devices.",
+    "bbox": [
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_25.jpg",
+    "caption": "Supplementary Fig. 25 | Photovoltaic parameters of the devices post-treated by HABr/CF containing different ratios of \\(\\mathrm{Br}_2\\) as additives. (a) \\(V_{\\mathrm{OC}}\\) , (b) \\(J_{\\mathrm{SC}}\\) , (c) fill factor and (d) efficiency.",
+    "bbox": [],
+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Supplementary_Figure_12.jpg",
+    "caption": "Supplementary Fig. 12 | SEM images of perovskite films without and with HABr/Cl₂-CF treatment. The perovskite films were fabricated by the one-step spin-coating method and showed almost a PbI₂-free surface.",
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+    "type": "image",
+    "img_path": "images/Figure_2.jpg",
+    "caption": "Response Figure 2: DNMT1 knockout leads to higher abundance of cytoplasmic dsRNA in TC1 cell (A) and MCA205 (B).",
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+  {
+    "type": "image",
+    "img_path": "images/Figure_3.jpg",
+    "caption": "Response Figure 3: Our analysis of the LUAD cohort in the TCGA database revealed that patients with high Myc expression are predominantly enriched in the cell cycle signaling pathway.",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_4.jpg",
+    "caption": "Response Figure 4: (A) Differential Gene Expression Profiles Following Myc Deletion. (B) Altered CDK Family Gene Expression in Response to Myc Deletion. (C) Shared Downregulated Genes Following Myc and NAT10 Deletion.",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_5.jpg",
+    "caption": "Response Figure 5: High-dose (200 mg/kg) remodelin significantly inhibited tumor growth compared to low-dose (100 mg/kg) and Normal saline in Nude/Nude mice.",
+    "bbox": [
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+  {
+    "type": "image",
+    "img_path": "images/Figure_10.jpg",
+    "caption": "Response Figure 10: (C) Tumor growth curves and weight of WT or sgNAT10 TC1 cells inoculated into C57BL/6N mice (n=5) treated with neutralizing antibodies targeting IFNAR1 or PBS injected every 2–3 days.",
+    "bbox": [],
+    "page_idx": 13
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_12.jpg",
+    "caption": "Response Figure 12: DNMT1 knockout leads to higher abundance of cytoplasmic dsRNA in TC1 cell (A) and MCA205 (B).",
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+  {
+    "type": "image",
+    "img_path": "images/Figure_13.jpg",
+    "caption": "Response Figure 13: (H) Western blot analysis of NAT10, DNMT1, MYC and CDK2 in matched WT and siNAT10 A549 tumor cells. \\(\\beta\\) -actin was used as a loading control.",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_14.jpg",
+    "caption": "Response Figure 14: The expression levels of CDK2 were assessed in relation to high and low NAT10 expression groups, using data from TCGA.",
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+  {
+    "type": "image",
+    "img_path": "images/Figure_16.jpg",
+    "caption": "Response Figure 16: The acRIP-seq data for WT and sgNAT10 cell lines were visualized using the IGV software.",
+    "bbox": [],
+    "page_idx": 20
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_17.jpg",
+    "caption": "Response Figure 17: (B) The peaks of myc in WT and sgNAT10 TC1 cells from Ribo-seq data were visualized using the IGV software.",
+    "bbox": [
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+    "page_idx": 22
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "(B) For the multivariate COX analysis, we utilized \"TCGA-biolink\" package to obtain survival and status data for TCGA-LUAD cohort. Multivariate COX regression analysis was conducted using the \"survival\" package, with the confidence interval for the hazard ratio (HR) set at 95%.",
+    "bbox": [],
+    "page_idx": 24
+  }
+]

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+    "caption": "Figure 5.",
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+  {
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+    "caption": "Figure S10.",
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+    "caption": "Figure 5.",
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+    ],
+    "page_idx": 20
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_6.jpg",
+    "caption": "Figure 6.",
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0f4d1e9b0c508ff4216b04d82c08117885c301b0ac50f7ffce3add99051c992a/peer_review/images_list.json

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+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R1. Long-term stability of NW networks. a. Transresistance pattern of an Ag NW network after deposition and b. evolution over time of transresistance values of all the 208 configurations, monitored by placing the ERT setup in a hermetically closed box to limit the interaction with the environment. After initial stabilization, transresistance values of the multiterminal NW network tend to stabilize to near constant values and no network failures were observed after 20 days.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_1.jpg",
+    "caption": "Figure R2. Repeatability and consistency of the network output under the same input pattern. a. Input pattern and corresponding stimulating input voltage pattern in the spatio-temporal domain. b. experimental configuration for NW network stimulation. c. Time traces of output voltages for 30 stimulations with the pattern reported in panel a. d. Detail of time traces reported in panel a with a focus on the output response waveform of the output when the corresponding input is directly stimulated. e. Detail of time traces reported in panel a with a focus on the output response waveform of the input when the corresponding input is not directly stimulated. Adapted from ref. [6].",
+    "bbox": [
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+    ],
+    "page_idx": 6
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_2.jpg",
+    "caption": "Figure R3. Repeatability of NW network dynamics in samples with nominally identical characteristics. Response of a. NW network 1 and b. NW network 2 of an arbitrary stimulation voltage waveform. Stimulation voltage waveforms, composed of two spaced voltage pulses with amplitude of 0.8 V and 3 V, respectively, and length of 10 s, were applied to selected contacts of two NW networks with nominally identical characteristics. Contacts selected for stimulation (6 and 15) are highlighted in insets. The effective conductance in between pulses was monitored by applying a read voltage of \\(10\\mathrm{mV}\\) .",
+    "bbox": [
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+    "page_idx": 8
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_3.jpg",
+    "caption": "Figure R4. Mean and standard deviation \\((\\times 100)\\) of measured ERT patterns evaluated by repeating the ERT measurement protocol 10 times on a NW network in the pristine state. A standard deviation in transresistance values \\(< 0.5\\%\\) was observed, showing that the measurement protocol maximizes the signal-to-noise ratio while preventing the onset of sample alterations.",
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+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_4.jpg",
+    "caption": "Figure R5. Experimental investigation of 16-electrode ERT spatial resolution. a. Fluorinated tin oxide (FTO) thin film with a thin linear cut (white marker of about \\(50 \\mu \\mathrm{m}\\) ). Before the linear cut, the FTO sample was characterized by a uniform conductivity of \\(150 \\mathrm{mS}\\) [10]. b. Conductivity dip observed in the diagonal conductivity profile of the sample (in the direction of the black arrow in the map of panel a), where the full width at high maximum corresponds to \\(\\approx 1.7 \\mathrm{mm}\\) .",
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+    "page_idx": 10
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_5.jpg",
+    "caption": "Figure R6. Emergent behavior of the NW network connectome at the micro/nanoscale. a. NW network topology simulated by dispersing 1D objects (1800 NWs) on a 2D plane ( \\(500 \\times 500 \\mu \\mathrm{m}^2\\) ), where red dots represent NW midpoints while blue dots represent NW junctions, and b. corresponding graph representation. c. Electrical backbone of the network when stimulated in between source (red marked node, upper left) and ground node (black marked node, bottom right), d. corresponding visualization of the potential distribution across graph nodes when a voltage difference is applied between these nodes, and e. corresponding voltage distribution across the 2D plane. f. Activation pattern of the network after stimulation in between source and ground nodes with a voltage pulse, showing the emergence of a conductive pathway composed of multiple branches that connects source and ground nodes. Red intensity is proportional to edge conductance, blue intensity is proportional to node voltage.",
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+    "img_path": "images/Figure_1R.jpg",
+    "caption": "Figure 1R. Optional figure for Figure 3.",
+    "bbox": [],
+    "page_idx": 0
+  },
+  {
+    "type": "image",
+    "img_path": "images/Figure_unknown_0.jpg",
+    "caption": "Figure R2. Linear circular relationship of body mass and activity at the regional level. If the fitted line lays outside the confidence values (grey area) of a null hypothesis, the alternative hypothesis is accepted. We found that in general, large carnivores and omnivores are more likely active during hours of the day, and we find the opposite for herbivores. Larger species active most likely during the night. We found that insectivores are inconsistent, in the Neotropics large species were more active during the day, while in the Indo-Malayan tropics large species tended to be nocturnal. It was insufficient observation to test with this framework the relationship of body mass with the activity of omnivores and insectivores in the Afrotropics.",
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+    "page_idx": 16
+  }
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