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135
b6a5d62d-61d3-4c59-a97c-c59e29a1f5ca
Which of the following opioid analgesic acts primarily through K opioid receptors?
Pentazocine
Methadone
Buprenorphine
Pethidine
0a
single
(Ref: KDT 6/e p464, 465) Pentazocine can cause dysphoric reactions (hallucinations) by stimulating the K receptors.
Anatomy
Other topics and Adverse effects
e2a9d69e-1cd5-489f-90ab-70a5df8811e7
Kappa statistics is used to measure
Inter examiner validity
Correlation
Regression
Proportion
0a
single
null
Dental
null
8068717f-962e-4012-9a31-263500b618e0
Which of the following is not a component of Glasgow Coma Scale?
Eye opening
Motor response
Pupil size
Verbal response
2c
single
Ans. is 'c' i.e. pupil size
Surgery
null
a2841be9-4b54-4065-9373-98b9919af87b
Form the normal bacterial flora of the conjunctiva
Corynebacterium xerosis
E. Coli
Streptococci
All of the above
0a
multi
Ans. Corynebacterium xerosis
Ophthalmology
null
412ca983-9c2d-44d9-a0c9-e267a34917f8
Hypoceruloplasminimia is associated with which abnormality?
Menkes disease
Alzheimer's disease
Schizophrenia
Obsessive-compulsive disorder
0a
single
(A) Menkes disease # Deficiency or Lower-than-normal ceruloplasmin levels may indicate the following:> Wilson disease copper storage disease)> Menkes disease (Menkes kinky hair syndrome) (rare - UK incidence 1/100,000)> Overdose of Vitamin C> Copper deficiency> Aceruloplasminemia> Excess or Greater-than-normal cerulopl...
Psychiatry
Miscellaneous
4a161c38-60e3-4902-8e9b-a09997c19b0d
According to triage patient having visible bleeding should be treated in:
Emergency.
Delayed.
Minimal treatment.
No treatment.
0a
single
null
Surgery
null
819bd3ae-4e3e-4a00-9abc-2f2e5d9b14bd
Apart from plasmodium, which of the following can infect RBCs in "ring forms"?
Babesia microti
Tyrpanosomas
Schistosomia
Microfilaria
0a
single
Ans. a (Babesia microti). (Ref. Harrison's, Principles of Internal Medicine, 16th ed., pg1232)Babesiosis (B. microti)# Babesiosis is a worldwide protozoan disease of animals that is transmitted by ticks; humans are infected incidentally and initially develop a nonspecific febrile illness that can lead to hemolytic anem...
Microbiology
Parasitology
0cd52b72-aa15-4ba8-9f5d-e12c5f7b2f95
Following clostridia are saccharolytic except ?
Welchii
Sporogenes
Septicum
Oedematiens
1b
multi
Ans. is 'b' i.e., Sporogenes . Clostridia may break down carbohydrate for energy (sacchrolytic) or break down protein for energy (proteolytic) or both. Different clostridia have different pattern :- . Both proteolytic and saccharolytic - Predominating proteolytic --> CL sporogenes, Cl botulinum A .B.F., Cl. bifermentan...
Microbiology
null
a3136ec5-a8f7-41e3-9ea0-943e066f511a
A 32-year-old primi gravida presents with DVT. There is history of 2 episodes of DVT in the past and was diagnosed to have antiphospoholipid antibody. Next step in management is:
Aspirin alone
Aspirin and heparin
LMWH
Warfarin for 6 months
1b
multi
Ans: B (Aspirin and heparin) Ref: Maternal-Fetal Medicine edited by Mary E. D'Alton. pg: 10-14 and DC Dutta's Textbook of Obstetrics. 7th edition, pg: 343 Explanation: "ACOG 2005 guidelines recommends low dos aspirin t5-80 mg orally per day along with unfractionated heparin 5000 unit subcutaneously twice daily. The the...
Unknown
null
33d775c8-dcc5-4b61-93fa-841c569fac55
Iridocorneal endothelial syndrome is associated with –
Progressive atrophy of iris stroma
Bilateral stromal edema of iris & cornea
Deposition of collagen in Descemet's membrane
Deposition of glycosaminoglycan in Descemet's membrane
0a
single
Iridocorneal endothelial (ICE) syndrome is characterized by abnormal corneal endothelium which causes :- Iris atrophy, Secondary angle closure glaucoma in association with characteristic peripheral anterior synechiae, Corneal edema. Option 'c' may cause confusion here. You should keep in mind that in iridocorneal endot...
Ophthalmology
null
f9780cb1-f622-4bfc-a6cc-4626abeba48b
An elderly man complains of ear pain. During evaluation, the physician asks if the patient has tinnitus. What is tinnitus?
A subjective sensation of noise in the head
A complication of chronic metal ingestion
An audible cardiac murmur
Dizziness with sounds
0a
single
Tinnitus is the perception of abnormal noise in the ear or head. It is usually attributed to a sensory loss; pulsatile tinnitus occurs with conductive hearing loss and is due to carotid pulsations becoming more apparent.
Surgery
Nervous System
99dafc79-4384-4222-bb13-bdbf56f7d5be
A 6 year old child with IQ of 50. Which of the following can the child do?
Identify colours
Read a sentence
Ride a bicycle
Copy a triangle
0a
single
IQ is defined by as the mental age divided by the chronological age multiplied by 100. In this case, a child of 6 years of age with an IQ of 50%, means that his mental age is that of a 3 year old child. At 3 years of age, a child can identify two colours. Ref: Essential paediatrics by OP Ghai, 6th edition, Page 543.
Pediatrics
null
b0cc354e-1640-4dd3-b2f2-dff8d51018a7
In fracture surgical neck of humerus, the following nerve injury is common:
Axillary
Radial
Ulnar
Median
0a
single
A i.e. Axillary
Surgery
null
946ee136-fa79-453b-85d5-160ed33bef66
Not an indication for blood transfusion
Moderate anemia at 24-30 weeks
Severe anemia at 36 weeks
Blood loss anemia
Refractory anemia
0a
single
Indications for Blood Transfusion  To correct anemia due to blood loss and to combat postpartum hemorrhage Patient with severe anemia seen in later months of pregnancy (beyond 36 weeks) Refractory anemia: Anemia not responding to either oral or parenteral therapy in spite of correct treatment Associated infection
Gynaecology & Obstetrics
null
6025f06f-f128-461f-a138-a489777e81a3
Trans-placental spread is least associated with?
HSV
Rubella
HBV
HIV
0a
single
HSV infection may be acquired in utero, during the birth process, or during the neonatal period. Intrauterine and postpartum infections occur infrequently. Most cases of neonatal herpes result from maternal infection and transmission, usually during passage through a contaminated infected birth canal of a mother with ...
Pediatrics
null
0dc38ea6-216b-4c27-9cb9-e28b3cd4cf74
Ovum is released due to
FSH
LH
Prolactin
HCG
1b
single
Ovulation-the discharge of a secondary oocyte from the Graafian follicle; in an adult woman, this normally occurs at intervals of about28 days and alternates between the two ovaries. As a rule, only one secondary oocyte is produced, but occasionally ovulation produces two or more; if more than one subsequently become f...
Physiology
Endocrinology
ca367e87-de96-4cb7-a097-6be2a041feb1
Sholy after the administration of an inhalational anesthetic and succinylcholine for intubation prior to an elective inguinal hernia repair in a 10-year-old boy, he becomes markedly febrile, displays a tachycardia of 160, and his urine changes color to a dark red. Which of the following is the most appropriate treatmen...
Complete the procedure but pretreat with dantrolene prior to future elective surgery.
Administer inhalational anesthetic agents.
Administer succinylcholine
Hyperventilate with 100% O2 .
3d
single
The cause of malignant hypehermia is unknown, but it is associated with inhalational anesthetic agents and succinylcholine. It may develop in an otherwise healthy person who has tolerated previous surgery without incident. It should be suspected in the presence of a history of unexplained fever, muscle or connective ti...
Anaesthesia
Miscellaneous
b3fabf8d-08ee-45fe-b5df-104019b158e9
A gastric biopsy is performed on a patient with suspected graft-versus-host disease following bone marrow transplantation. The biopsy demonstrates many isolated dying epithelial cells in crypts showing fragmented, hyperchromatic nuclei and small discrete blebs containing both cytoplasm and nuclear fragments. The biopsy...
Apoptosis
Caseous necrosis
Coagulative necrosis
Gangrenous necrosis
0a
multi
The changes described are those of apoptosis, which is a form of programmed cell death. Apoptosis can be seen in a variety of settings. In this case, it is occurring in the context of graft-versus-host disease, which is mediated by CD8+ and CD4+ cells. Apoptosis also occurs during embryogenesis, during hormone-dependen...
Pathology
null
5dd3a208-0a47-43af-ab7d-3830502df7d5
Varenicline is used in
Pulmonary hemosiderosis
Sleep apnea
Anti-trypsin deficiency
Nicotine dependency
3d
single
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor paial agonist. Specifically, varenicline is a paial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor Ref Davidson 23rd edition pg 578
Medicine
Respiratory system
f297406b-3c7e-4bb2-9faa-c777e105c505
Cyst seen in vagina are all except:
Nebothian cyst
Gartner's cyst
Bartholin's cyst
Inclusion cyst
0a
multi
Ans: A (Nebothian cyst) Ref: Shows Textbook of Gynecology 15th ed pg 136Explanation:VAGINAL CYSTSVaginal cysts are rare and are located more commonly in anterior vaginal wallGartner's cystArises from remnants of mesonephric ductLies in anterolateral aspect of vaginal wallSmall cyst is asymptomaticLarge cyst causes dysp...
Gynaecology & Obstetrics
Miscellaneous (Obs)
d071e619-2619-499f-b54f-d8e45a9b54da
Features of achalsia cardia are all of the following except: March 2009
Regurgitant vomiting
Elongated and dilated esophagus
Rat-tail deformity and filling defect on barium study
Increased difficulty in swallowing
2c
multi
Ans. C: Rat-tail deformity and filling defect on barium study Dysphagia is the most common presenting symptom in patients with achalasia. The ingestion of either solids or liquids can result in dysphagia. Emotional stress and the ingestion of cold liquids are well-known exacerbating or precipitating factors. 80-90% of ...
Surgery
null
5294b9e6-443e-447a-b789-fe44db1e5e21
A 6 year old girl presents with Recurrent E.coli infection in urine. Ultrasound of abdomen shows Hydroureter and Hydronephrosis. Micturating cysto – urethrogram shows filling defect in urinary bladder. The likely diagnosis is –
Sacrococcygeal Teratoma
Vesicoureteric Reflux – grade II
Duplication of Ureter
Ureterocele
3d
single
IVP in ureterocele usually shows a round filling defect, sometimes large, in the bladder corresponding to the ureterocele, and characteristic finding of duplication of the collecting system (ureteroceles are nearly always associated with ureteral duplication) Ureterocele : Is a cystic dilatation of the terminal ureter...
Pediatrics
null
5ebc3bc6-5483-4f16-bdb5-6d95fcd15958
Orchidopexy is done in cases of undescended testes at the age of
Infancy
1-2 yrs
5 yrs
Puberty
0a
single
Ans. is 'a' i.e. Infancy Campbell's Urology writes - "Definitive treatment of an undescended testis should take place between 6 and 12 months of age. Because spontaneous descent occurs in most boys by 3 months of age and uncommonly thereafter, earlier interventions should be considered in order to theoretically prevent...
Surgery
Miscellaneous (Testis & Scrotum)
3458f971-59ef-4497-ab93-01e7e5b570bc
A 45 year old woman develops abdominal and pelvic discomfo. Physical examination reveals a large mass in the right lower quadrant, which is surgically resected. The mass consists of a large (25 cm) cystic sac containing thick mucinous fluid within a thin wall. On careful inspection, the pathologist finds an area of inc...
Borderline mucinous tumor
Mucinous cystadenocarcinoma
Mucinous cystadenoma
Serous cystadenocarcinoma
0a
multi
Classification of ovarian tumors, like testicular tumors, is based on putative cell of origin. Thus, ovarian tumors can be divided into neoplasms of germ cells,surface epithelium, or stromal origin. Two thirds of all ovarian neoplasms derive from the surface (coelomic) epithelium. These cystic tumors may contain clear ...
Gynaecology & Obstetrics
null
291e3856-795c-4c4d-87ef-69cb12a74ab8
A man is brought to casualty who met with A. He sustained multiple rib fractures with paradoxical movement of chest. Management is
Tracheostomy
Consult cardiothoracic surgeon
Strapping
Intermittent positive pressure ventilation
3d
single
Ventilator suppo with IPPV(intermittent positive pressure ventilation) is the treatment of choice.Assisted ventilation is required for several days until the chest wall stabilises.If ventilator suppo is required for more than 10 days,then tracheostomy is done to prevent laryngeal stenosis which can occur due to prolong...
Surgery
Cardio thoracic surgery
3d8129c9-cd7f-4217-af03-7b1886672d09
The hookworm thrives on ?
Whole blood
Plasma
Serum
RBC
1b
single
Ans. is 'b' i.e., Plasma Hook worms Ancylostoma duodenale - Old world hookworm Nector americanus - New world hook worm Habitat - Small intestine (Jejunum > duodenum > Ileum) Infective form - Filariform larva Mode of infection - Penetration of skin Plasma forms the main source of nourishment for hookworm, the red blood ...
Microbiology
null
1a840098-8004-4bef-967c-1f931be4fcf0
Which of the following penicillins has the best gram negative spectrum?
Methicillin
Ampicillin
Penicillin V
Cefixime
1b
single
null
Pharmacology
null
ac331422-2134-43a3-bf9d-60d4c273ec09
Eminectomy is done for treatment of:
TMJ ankylosis
TMJ dislocation
Coronoid fracture
All of the above
1b
multi
null
Surgery
null
8c7e3916-715d-4642-93af-fe0e15179b55
Which of the following is a RNA virus?
Measles virus
Herpes virus
Papaya virus
Adeno virus
0a
single
null
Microbiology
null
3f2da92e-7292-44bb-abde-0926d6670ec1
Following drugs are the first choice in treating patients with candidiasis except-
Fluconazole
Nystatin
Amphotericin B
Caspofungin
3d
multi
Ans. is "d' i.e., Caspofungin Choice of drugs for systemic mycosesDiseaseDrugs1st Choice2nd Choice1) Candidiasisoral/vaginal / cutameous deep / invasive AMB/VORIAMB/VORIHRFLU/CAS/POSA2. CryptococcosisAMB/+-5-FCFLU3. HistoplasmosisITR/AMBFLU4. CoccidioidomycosisAMB/FLUITR.'KTZ5. BlastomycosisITR/AMBKTZ/FLU6. Sporotricho...
Pharmacology
Anti-Fungal
3253af62-3b54-465e-a439-105e1ef4ddc8
All of the following are anti HIV agents except ?
Ritonavir
Acyclovir
Didanosine
Zidovudine
1b
multi
Ans. is 'b' i.e., Acyclovir
Pharmacology
null
7808cdb3-be99-4d58-8751-dea69c907d35
Which one of the following drugs of abuse is most typically associated with the illustrated complication??
Ketamine
Heroin
Cocaine
Phencyclidine
2c
multi
Answer C. CocainePerforation of the nasal septum and palate are well recognized complications of intranasal cocaine use.
Medicine
Drugs
acd0169d-8539-46e3-a289-41fca0afcff4
Most common symptom associated with adult OCD?
Pathological doubt
Need for symmetry
Sexual
Aggressive
0a
single
(a) Pathological doubt, Ref: Complete review of psychiatry by Dr. Prashant Agrawal, ed.,, 2018, ch- 7, pg. 164 Explanation: Variable % Obsessions (N=200) Contamination 45 Pathological doubt 42 Somatic 36 Need for symmetry 31 Aggressive 28 Sexual 26 Other 13 Multiple obsessions 60 Compulsions (N=200) Checking 63 Washing...
Psychiatry
Mood Disorders
45adff9e-d3b4-413b-abe3-bc8ffb51e1c5
Pralidoxime acts by -
Reactivating cholinesterase enzyme
Promoting synthesis of cholinesterase
Promoting synthesis of acetylcholine
Direct action on cholinergic receptors
0a
single
Ans. is 'a' i.e., Reactivating cholinesterase enzyme o Pralidoxime is most commonly used cholinesterase reactivater.OXIMESo Oximes 1 Pralidoxime 2-PAM, obidoxime and diacetyl-monoxime (DAM)J are used in organophosphatepoisoning.o Oximes acts by reactivating cholinesterase enzyme.o Mechanism of actionIn organophosphate ...
Pharmacology
Cholinergic System
fab52be2-1236-4ac4-b40f-95a9b9fd37dd
Malignant cells in urine cytology are most commonly seen in
Renal cell carcinoma
Prostate carcinoma
Urothelial carcinoma
Bladder carcinoma
2c
single
Ans. c (Urothelial carcinoma). (Ref. Harrison's Medicine 17th ed. 555)# Urothelial malignancy classically shows polychronotropism & multicentricity.# In urothelial or transitional carcinoma of renal pelvis or ureter, the examination of urine for malignant cells is positive and even may indicate whether tumor is well or...
Surgery
Urinary Tract
64e1a4a3-6e42-4b4a-a305-02547ef5dba6
Drug of choice for mushroom poisoning is :
Atropine.
Solefenacin.
Oxybutynin.
Tolterodine.
0a
single
null
Pharmacology
null
317c6251-f5b1-4b02-8baa-947e91e1d59f
Surya kant is prescribed with first generation antihistaminic. He should be advised to avoid:
Driving motor cycle
Consuming cheese
Physical exercise
All of the above
0a
multi
Ans. A. Driving motor cycleFirst generation antihistaminic like promethazine, diphenhydramine crosses the blood brain barrier and have higher incidence of sedation. Another property of these drugs is that they show anticholinergic side effects. Due to this patient is asked not to drive any vehicle.
Pharmacology
Miscellaneous (Pharmacology)
3a6e9e54-bf62-4045-98be-e492013c29ee
Pivot shift test is positive with
Anterior cruciate ligament tear
Posterior cruciate ligament tear
Medial meniscus injury
Lateral meniscus injury
0a
single
Ans. a (Anterior cruciate ligament tear) (Ref. Adam's orthopedics 11th/pg, 315-325)Knee Joint Injuries1Normal range of motion# Flexion: 135 degrees# Extension: 0 to 10 degrees above horizontal plane2Patellar apprehension test# Evaluates for patella subluxation3Anterior cruciate ligament (ACL) stability tests# Lachman t...
Orthopaedics
Injuries Around the Thigh & Knee
b512d30c-b34d-48fe-a7ac-bc6346f0b8b3
Antidepressant drug used in nocturnal eneuresis is -
Imipramine
Fluoxetine
Trazdone
Sertaline
0a
single
Drugs used in nocturnal enuresis are imipramine and desmopressine.
Psychiatry
null
f0548c9a-9604-49d4-9507-39c7b55820d3
A pregnant lady at 32 weeks of gestation presents with a BP of 160/110 mmHg, proteinuria with retinal haemorrhage. What is the definitive treatment of choice in this patient?
Ritodrine
Nifedipine
Magnesium sulphates
Termination of pregnancy
3d
single
This patient is showing features of severe hypeension which is an indication for delivery. Induction of labour is the definitive treatment of choice which is most preferable. In order to prevent the onset of seizures magnesium sulfate prophylaxis should be given. Features of severe pre eclampsia are: BP > 160/110 >- 3 ...
Gynaecology & Obstetrics
null
cf641071-6dbd-4872-b895-c2a6cacf6688
Which is not a component of APGAR Score –
Colour of the body
Muscle tone
Heart rate/minutes
Respiratory rate per minute
3d
single
null
Pediatrics
null
3761d425-1996-4438-b8ee-dc77c1e16d81
Chromosome in which centromere is close to one end which result in short arm being very short is which type of chromosome?
Metacentric
Submetacentric
Telocentric
Acrocentic
3d
single
Ans. d (Acrocentric). (Ref. Cell & Molecular Biology by DeRobertis, 7th /pg. 348)CHROMOSOMES# The entire genetic information contained in the genes is packaged in the chromosomes. All the somatic cells of an individual organism contain the same number of chromosomes.# Genes are arranged linearly on the chromosomes and ...
Anatomy
General
52326d02-8302-4436-be24-ea5a5f44d82b
Which among the following is a mechanism of action of colchicine?
Suppression of immunity
Increase in uric acid excretion
Decrease in uric acid synthesis
None of the above
0a
multi
Colchicine is known to suppress many immune functions in the setting of crystal induced ahritis by 1. decreasing neutrophil chemotaxis 2. decreasing neutrophil adhesion 3. decreasing release of multiple inflammatory mediators 4. decreasing phagocytosis of urate crystals by neutrophils. Mechanism: Colchicine binds to tu...
Pharmacology
null
870d7455-f9a8-4e98-9576-0886fd889ee7
Bollinger bodies are seen in -
Chickenpox
Cowpox
Fowlpox
Smallpox
2c
multi
null
Microbiology
null
d1869c29-3776-4ff6-85b8-34120edf484b
About Kawasaki disease all are true, EXCEPT:
Mucocutaneous lesions
Coronary aery is involved
Seen in children
Suppurative lymphadenopathy
3d
multi
Suppurative lymphadenopathy
Medicine
null
6f9e2805-85d6-47e9-934d-03b202f130b2
Which of the following is a L-type calcium channel blocker:
Nifedipines
Amlodipines
Diltiazem
All of the above
3d
multi
Ans. (d) All of the aboveRef. KDT 6th ed. / 528Types of Calcium Channel Blocker L-Type (long lasting current)T-type (transient current)N-Type (neuronal)Locations and function* Excitation -contraction coupling in cardiac and smooth muscle* SA, A-V node: conductivity* Endocrine cell: Hormone release* Neurons: transmitter...
Pharmacology
Anti-Hypertensive
bafc4838-ff95-4fac-bf18-7522993b43cf
Male to male transmission is seen in -
Autosomal dominant diseases
Autosomal recessive
X-linked dominant
Mitochondrial disease
0a
single
Robbins basic pathology 9th edition page no 218,Heading=Transmission patterns of single-gene disorders Disorders of autosomal dominant inheritance are manifested in the heterozygous state, so atleast one parent in an index case usually is affected, both males and females are affected, both males and females are affecte...
Pathology
General pathology
5783b99d-68d8-43db-8877-c1357e81888d
Sputum from one patient is disinfected immediately following expectoration, this is known as:
Concurrent
Pre current
Recurrent
Terminal
0a
single
Ans: a (Concurrent) Ref: Park, 19th ed, p. 108Sterilization is the process of destroying all life including spores.Disinfection- is the killing of infectious agents outside the body by direct exposure to chemical or physical agents.Types of disinfection:a) Concurrent disinfection- It is the application of disinfective ...
Social & Preventive Medicine
Communicable Diseases
37465750-3029-43ee-8553-183f8aa34f5c
'Sequestration' is best defined as:
A piece of dead bone
A piece of dead bone surrounded by infected tissue
A piece of bone with poor vascularity
None of the above
1b
multi
Ans. B. A piece of dead bone surrounded by infected tissue (Ref. Maheshwari ortho 3rd/pg.l60)Maheshwari orthopaedics 3rd/pg. 160...."Sequestrum is a piece of dead bone, surrounded by infected granulation tissue trying to 'eat' the Sequestrum away"CHRONIC OSTEOMYELITISPresents in 3 forms:A. Chronic osteomyelitis seconda...
Orthopaedics
Infection of Bones & Joints
9d65ee9b-e380-4fa0-8108-195f071bf656
Dose of Rabies immunoglobulin is?
10 IU/Kg body weight
15 IU/kg body weight
20 IU/kg body weight
25 IU/kg body weight
2c
single
Anti rabies serum is given in class III bites (Single or multiple transdermal bites or scratches, licks on broken skin, Contamination of mucous membranes with aalvia, exposure to bats) It is found to prolong the incubation period. Passive immunization in rabies may be given by : Horse Anti-rabies serum : 40 IU/kg body ...
Unknown
null
48b32cb1-8b7a-4797-9274-e8697ab08c01
Progressive cognitive impairment is Alzheimer's disease is characterized by
Nominal aphasia
Recent memory loss
No behavioral abnormalities
All
1b
multi
Memory impairment is typically an early and prominent feature in dementia, especially in dementias involving the coex, such as dementia of the Alzheimer's type. Early in the course of dementia, memory impairment is mild and usually most marked for recent events. As the course of dementia progresses, memory impairment b...
Psychiatry
Organic mental disorders
ac378e3c-74c8-48d7-ac19-bce3885d4312
Mesothelioma is most commonly caused by?
Asbestosis
Silicosis
Anthracosis
Coal workers pneumoconiosis
0a
single
Ans. (a) AsbestosisRef: Harrison 19th ed. /1689* Working with asbestos is the most common risk factor for mesothelioma.* Indeed, the relationship between asbestos and mesothelioma is so strong that many consider mesothelioma a "signal" or "sentinel" tumor.* In rare cases, mesothelioma has also been associated with irra...
Medicine
Pneumoconiosis
1eefadf6-c0eb-44cd-8281-d04adeb68264
The following rosette cataract is seen with
Steroid induced cataract
Traumatic cataract
Syndermatotic cataract
Rose thorn injury to lens
1b
single
null
Ophthalmology
null
7da0a3c4-316b-40e7-9a91-241483ab4691
Which of the following is true about typhoid?
Fecal carriers are less common
Vi antibodies are present in about 80% of chronic carriers
Gall bladder usually not involved in carrier state
Tetracycline is the DOC for carriers
1b
multi
Convalescent carriers excrete the bacilli for 6-8 weeks.Persons who excrete the bacilli for more than a year after a clinical attack are called chronic carriers.In chronic carriers, the organism persists in the gallbladder. Vi antibodies are present in about 80% 0f chronic carriersFecal carriers are more frequent than ...
Social & Preventive Medicine
Communicable diseases
9f8dcde7-4ab4-4390-8ecc-387c17e340ce
A 5 yr. old male child has multiple hyperpigmented macules over the trunk. On rubbing the lesion with rounded end of pen, he developed urticarial wheal, confined to border of lesion, most likely diagnosis is:
Fixed drug eruption
Lichen planus
Urticaria pigmentosa
Urticarial vasculitis
2c
single
Ans. C. Urticaria pigmentosa* It is urticaria pigmentosa.* It is cutaneous mastocytosis presenting with pigmented lesions.* On rubbing the lesions mast cells degranulate releasing histamine.* This produces the wheal and flare of the lesion. It is known as Darier's sign.Epidermal acantholysis in mid epidermis with "dila...
Skin
Miscellaneous
5e58e064-06c9-44f7-8a4b-f79b38a6adf0
Long term control of diabetes is assessed by
Random blood sugar
Microalbuminuria/ creatinine ratio
HbA2
HbA1c
3d
single
Ans. D i.e. HbA1c
Medicine
null
7a7f5bfe-c812-4fae-8b19-927825035080
Primary open-angle glaucoma is associated with all of the following except:
Diabetes mellitus
Myopia
Hypehyroidism
Pars planitis
3d
multi
Ans. Pars planitis
Ophthalmology
null
b0dbf3bb-0859-4668-82ef-9d12ec3333b6
Direction of water jet while doing syringing of ear should be:
Anteroinferior
Posterosuperior
Anterosuperior
Posteroinferior
1b
single
In syringing (done to remove impacted wax) pinna is pulled upwards and backwards and a stream of water from the ear syringe is directed along the posterosuperior wall of the meatus.
ENT
null
de7b164f-b828-442f-bc44-3bf035863901
Biological value is maximum of:
Egg
Milk
Soyabean
Pulses
0a
single
Egg
Social & Preventive Medicine
null
f826865f-34c8-4391-a264-bfca803ad408
Among the given hormones which are stored the longest in a cell
Insulin
T3
PTH
Testosterone
1b
single
Hormone Supply Stored in CellSteroids and 1,25(OH)2-D3NoneCatecholamines and PTHHoursInsulin DaysT3 and T4WeeksRef: Harper; 30th edition; Pg:515
Biochemistry
Structure and function of protein
96d171c3-ed59-4539-9f65-2991a015773a
The most common effect of colchicine which is dose limiting is :
Diarrhea
Dyspepsia
Retinal damage
Loss of taste sensation
0a
single
null
Pharmacology
null
f1d1ed18-131e-4d84-ae73-40c6007f2b84
Not a feature of Treacher-Collins syndrome:
Deafness
Colobomas of lower eyelid
Hypoplasia of zygomatic bone
Mongoloid slant of palpable fissure
3d
single
Ans. D. Mongoloid slant of palpable fissureMandibulofacial dysostosis is also known as Franceschetti-Klein syndrome or Treacher-Collins syndrome.Important features are as under:MicrognathiaColobomas of lower eyelidSunken cheek bonesBlind fistulas between the angles of mouth and earsDeformed pinnasAtypical hair growth e...
Pediatrics
Genetics And Genetic Disorders
9dacd22c-982f-4023-a8df-4a2b7a46a0b8
Most potent stimulator of NaiveT-cells -
Mature dentritic cells
Follicular dentritic cells
Macrophages
B-cell
0a
single
Question repeated
Pathology
General pathology
45ca83ff-dc48-49a8-9d42-7ac346189b18
Layers of the scalp include all of the following except-
Galea aponeurotica
Adventitious layer
Skin
Pericranium
1b
multi
Ans. is 'b' i.e., Adventitious layer Layers of scalp have been explained in NEET Dec.-16
Anatomy
Head & Neck
e8b96f11-a402-4f70-9684-d0ba21a935a4
Which of the following adverse effects characteristically associated with methysergide ?
Pulmonary hypertension
Retroperitoneal fibrosis
Hepatotoxicity
Ischemic heart disease
1b
multi
null
Pharmacology
null
f9e0dd56-435f-4f22-aae9-ee8dea11f162
Binge eating disorder is characterized by ?
Normal weight
Weight loss
Obesity
Self induced vomiting
2c
single
Ans. C. ObesityBinge eating disorder (BED) is characterized by insatiable cravings that can occur any time day or night, usually secretive, and filled with shame.There are no comPensatory mechanisms associated with the binge to get rid of calories, so individulas with BED are more likely to be overweight or obese, whil...
Psychiatry
null
b8930b48-32e6-4700-9951-bd12426ad066
Anemia of chronic disease is characterised by
Increased sideroblast
Increased TIBC
Increased bone marrow iron
Increased protoporphyrin
2c
single
(Ref: Robbins 8/e p662) Anemia of chronic disease- Impaired red cell production associated with any chronic diseases that would be infectious/inflammatory/neoplastic. Chronic diseases produce a cytokine “IL-6” that increases the production of hepcidin from liver.  Hepcidin inhibits ferroportin function in macrophages ...
Unknown
null
629939d5-2989-485c-8051-7ec91f016bf0
Choose the true statement about mit DNA:
Few mutation compared to nuclear DNA
It has 3x109 base pairs
It receives 23 chromosomes from each parent
It codes for less than 20% of the proteins involved in respiratory chain
3d
multi
Ans. D. It codes for less than 20% of the proteins involved in respiratory chainIn ETC there are around 67 subunits, out it 13 proteins are coded by Mit DNA, which comes around 19%.Mitochondrial DNA has high mutation rate almost 5 to 10 times that of nuclear DNA.It has 16,569 bpMitochondrial DNA has maternal inheritanc...
Biochemistry
Molecular Genetics
672c4c46-5bef-420f-bd74-77a5e0141f13
Cataract in newborn is:
Zonular
Coronary
Snowflake
Coical
0a
single
Ans. Zonular
Ophthalmology
null
df81c571-eab0-42e3-9d0e-0663e4b772bc
Drug of choice for treatment of type 2 Brittle Asthma is -
b-adrenergic agonist
Inhaled corticosteroids
Antileukotrines DM
Subcutaneous epinephrine
3d
single
Ans. is 'd' i.e., Subcutaneous epinephrine o Brittle asthma is a type of asthma distinguishable from other forms by recurrent, severe attacks.o There are two subtypes divided by symptoms: Type 1 and Type 2, depending on the stability of the patient's maximum speed of expiration, or peak expiratory flow rate (PEFR).o Br...
Medicine
Asthma
669ac0aa-46c0-4b8c-803f-922d2065eaa5
A 22-year-old woman is admitted to the hospital because of right-hand anaesthesia, that developed after an argument with her brother. She is in good spirits and seems unconcerned about her problem. There is no history of physical trauma. The neurologic examination is negative EXCEPT for reduced sensitivity to pain in a...
Body dysmorphic disorder
Histrionic personality disorder
Parietal brain tumor
Conversion disorder
3d
multi
(D) Conversion disorder # Conversion disorder is characterized by symptoms or deficits of die voluntary motor or sensory functions dial cannot be explained by neurological or other medical conditions.> These symptoms are precipitated by psychological conflicts.> Term 'Hysteria' was used in die nineteenth century (and d...
Pharmacology
Miscellaneous (Pharmacology)
ab7779d0-18c3-4d45-a732-33612120f24c
A person following a road-traffic accident presented in emergency with laceration of inguinal region. On examination there was swelling of inguinal region and distal pulsation was felt; internal iliac artery was normal, common iliac and external femoral artery was normal but common femoral vein is transected. Treatment...
Vein repair with continuity
Sclerotherapy
Ligation of femoral artery and vein
Amputation below knee
0a
single
null
Surgery
null
163ec7af-ce59-46da-afb3-4429b44ae682
A patient with ASD has the murmur similar to mitral regurgitation and left axis detion of 40 degrees. He is likely having:
TGA
Ostium secondum
Ostium primum
Floppy mitral valve
3d
single
Presence of pansystolic murmur of mitral regurgitation in a patient with ASD suggests the presence of ostium primum defect with cleft mitral leaflet or a floppy mitral valve with mitral valve prolapse. ECG shows right axis detion in ASD, and extreme left axis detion in ostium primum ASD. Clinical presentation of ostium...
Pediatrics
null
545927bc-c9c0-48c5-98a4-855a6e901674
GLUT 4 is present in -
Endothelium
Liver
Cardiac muscle
Lens
2c
single
Ans. is 'c' i.e., Cardiac muscle* GLUT4 transporters mediate insulin dependent glucose uptake in skeletal muscle, cardiac muscle and adipose tissue
Biochemistry
Carbohydrates
e06652e3-5225-4e8b-ace7-cf5b9a12a29e
Which is the best test to detect pulmonary embolism
D dimer assay
MRI
Ventilation Perfusion scan
CT with IV contrast
3d
single
CTPA is the first-line diagnostic test. It has the advantage of visualising the distribution and extent of the emboli or highlighting an alternative diagnosis, such as consolidation, pneumothorax or aoic dissection. The sensitivity of CT scanning may be increased by simultaneous visualisation of the femoraland poplitea...
Medicine
Respiratory system
106bb8c1-7fb2-40fb-8ac2-327f733b2492
A 54-year-old clerk complains of having had dysphagia for 15 years. The clinical diagnosis of achalasia is confirmed by a barium study. What is TRUE in this condition?
The most common symptom is dysphagia.
In the early stages, dysphagia is more pronounced for solids than liquids
The incidence of sarcoma is increased.
Recurrent pulmonary infections are rare.
0a
multi
Dysphagia in esophageal achalasia is described as paradoxical in that it is more pronounced for liquids than solids. There are numerous reports of an increased incidence of carcinoma in achalasia, ranging from 3% to 10%. In 1975, Belsey reported a 10%. incidence in 81 patients in whom symptoms tended to occur at a youn...
Surgery
Stomach & Duodenum
dfd75847-f4df-40bb-ab84-fcb5038fefe3
Uveitis is caused by all except:
T.B.
Staphylococcus
Streptococcus
Klebsiella
3d
multi
Ans. Klebsiella
Ophthalmology
null
5cc9e218-a6f9-4ce9-acf2-f69baddbac40
Which of the following is false regarding plasmid
Circular genetic material
Double stranded DNA
Extra chromosomal
Synchronised with chromosomal multiplication
3d
multi
Plasmids contain their own signals for replication and can replicate independently.
Biochemistry
null
eadf0100-f37f-4bd3-af71-f15226951a7c
Commonest cause of right ventricular failure is ?
Corpulmonale
Pulmonary involvement
Endomyocardial fibrosis
Left ventricular failure
3d
single
Ans. is 'd' i.e., Left ventricular failureRight sided hea failureo Most common cause of right sided hea failure is left sided hea failure, i.e. right hea failure occurs as a consequence of left hea failure because left hea failure increases pressure in pulmonary circulation that produces an increased burden on the righ...
Pathology
null
a8638e28-2393-4823-9101-da47173a14e9
Which of the following anti-histaminie has very less cholinergic side effects?
Promethazine
Chlorpheniramine
Hydroxyzine
Loratidine
3d
single
Loratidine is a second generation anti-histamine which has lesser sedation and cholinergic side effects.
Pharmacology
null
a1baa515-c536-4d6e-b489-9ba378a09009
following are decomposition changes except
Discoloration
Discharge
Degloving
Dilatation
3d
multi
Decomposition changes Discoloration: greenish discoloration of right iliac fossa due to sulphmethemoglobin, marbling, discoloration under surface of liver, staining of aoa, blackish discoloration of skin is due to formation of ferric sulphide. Distension: abdomen, breasts, penis, scrotum, face bloated, eyes budget out ...
Forensic Medicine
Death and postmortem changes
a8338743-57d1-455a-b44b-69e9eb067a90
A 31 year old female patient complaints of bilateral impairment of hearing for the past 5 years. On examination, tympanic membrane is normal and audiogram shows a bilateral conductive deafness. Impedance audiometry shows normal curve and acoustic reflexes are absent. All of the following constitute pa of its treatment,...
Gentamicin
Hearing aid
Stapedectomy
Sodium fluoride
0a
multi
The patient is showing features of otosclerosis. It is a condition due to new spongy bone formation. About 50% of the cases may have a positive family history and deafness stas between the age of 20-30 years. Non surgical treatment of otosclerosis includes use of hearing aid and sodium fluoride. Use of high doses of so...
ENT
null
698b9d08-8ac1-42eb-bf13-8515cca5f63d
A 43-yrs-old female patients, who has sustained a head injury in a fall, has significant problems wit memory. Her brain injury is most likely to the
Temporal lobe
Frontal lobe
Parietal lobe
Occipital lobe
0a
multi
The area of the brain most closely associated with memory is the temporal lobe, paicularly the hippocampus. PE presents with a syncopal episode up to 15 percent of the time. Altered mental status and generalized seizures may also be the presenting complaint, especially in the elderly. The most common presenting symptom...
Surgery
null
1ee618bb-4cf0-470a-8895-0eaec35f9975
Antidote for ethylene glycol poisoning is/are: a) Methyl violet b) Fluconazole c) Fomepizole d) Ethyl alcohol
ac
cd
ad
bc
1b
single
null
Pharmacology
null
1f1c517b-5f2f-4232-a332-c14dabd8a883
Which among the following is not a beta lactamase resistant Penicillin?
Methicillin
Carbenicillin
Nafcillin
Oxacillin
1b
single
Ans. is 'b' i.e., Carbenicillin
Pharmacology
null
f6c76e86-a0e5-4407-93eb-010141dcddc8
Class IV Kennedy Classification is:
Bilateral edentulous area located posterior to the remaining natural teeth.
Unilateral edentulous area located posterior to the remaining natural teeth.
Unilateral edentulous area with natural teeth remaining both anterior to the remaining natural teeth and posterior to it.
A single but bilateral (crossing the midline) edentulous area located anterior to the remaining natural teeth.
3d
multi
The following is the Kennedy classification: Class I: Bilateral edentulous areas located posterior to the natural teeth. Class II: A unilateral edentulous area located posterior to the remaining natural teeth. Class III: A unilateral edentulous are with natural teeth remaining both anterior and posterior to it. Class I...
Dental
null
c87cd9ce-def0-49f6-a75d-60c0517a8d87
Earliest fetal anomaly to be detected by USG :
Hydrocephalous
Anencephaly
Achondroplasia
Spina bifida
1b
single
Anencephaly
Gynaecology & Obstetrics
null
c1a49e19-4984-4a6a-8acb-c927b5a920b6
A 54-year-old male nonsmoker is seen with complaints of a flulike illness. Initial symptomatic treatment is provided. Two days later, he returns, as he is still not feeling well. His primary physician prescribes a macrolide along with the symptomatic treatment. After 5 days of this treatment, the patient says he is run...
Septic ahritis
Endocarditis
Brain abscess
Reye syndrome
3d
multi
This x-ray shows a nonhomogeneous airspace density in the left middle and lower zones with areas of incomplete consolidation and evolving pneumatocele formation. The left diaphragm is raised and the trachea appears shifted to the left, suggesting loss of volume of the left lung. There is minimal blunting of the left co...
Radiology
Respiratory system
e94ea92f-3d1b-4f02-949c-e37f05e38d4f
Subclan steal syndrome is due to
Blockage of first pa of subclan aery
Blockage of second pa of subclan aery
Blockage of third pa of subclan aery
Thrombosis of subclan vein
1b
single
Subclan steal syndrome refers to steno-occlusive disease of the proximal subclan aery with retrograde flow in the ipsilateral veebral aery and associated cerebral ischaemic symptoms.CausesClinical presentationIpsilateral upper limbNeurological, radiationCongenital Weak or absent pulseDecreased blood pressure (>20 mmHg)...
Pathology
All India exam
81f3ce8d-ce5d-4da1-a6b3-b8228d4856ce
GABA is produced from:
Alanine
Glycine
Glutamate
Glutamine
2c
single
Glutamate
Physiology
null
4123ffcc-6830-456b-8b4e-669fac15fae4
Palpatory thud, an audible snap is seen in
Tracheal foreign body
Bronchial foreign body
Laryngeal foreign body
Foreign body in ear
0a
single
A foreign body in trachea may move up and down the trachea between the carnia and the undersurface of vocal cords causing "audible slap" and "palpatory thud&;.Symptoms and signs of foreign bodies at different levelsSite of foreign bodiesSymptoms and signsLarynxChoking, Cyanosis, Complete obstruction leading to death* P...
ENT
Larynx
d1a4d2e7-43f2-4634-b991-f4938c88cebb
A drug used in LUMINATE programme for non-infectious uveitis is –
Cyclosporine
Voclosporin
Methotrexate
Infliximab
1b
single
Voclosporin is an immunomodulatory drug which inhibits the enzyme calcineurin. The chemical structure of voclosporin is similar to cyclosporine with a difference in one amino acid, leading to superior calcineurin inhibition and less variability in plasma concentration. The LUMINATE (Lux Uveitis Multicenter Investigatio...
Ophthalmology
null
57815d37-3ae7-417d-ad46-4eccf10f80d5
Average of length of maxillary cuspid is:
26 mm
33 mm
21 mm
18 mm
0a
single
null
Dental
null
00b3f0c1-994f-4eb2-9caa-e37dd57c19c9
The nerve root blocked in pudendal block is
L 1,2,3
L 2,3
S 2,3,4
S 4
2c
single
Pudendal nerve block : Pudendal nerve arises from S2,3,4. Doesn't relieve the pain of labor Cause perineal analgesia and relaxation Ref: Dutta Obs 9e pg 480.
Gynaecology & Obstetrics
General obstetrics
609e514e-cfae-4b18-b4a2-b44e8807a427
A 45 year old male , known case of diabetes mellitus from last 15 years ,presents with Diabetic ketoacidosis . What shall be the initial line of management?
3 % saline
5% dextrose
0.9 % saline
Colloids
2c
multi
Diabetic ketoacidosis (DKA) is a problem that affects people with diabetes . It occurs when the body stas breaking down fat at a rate that is much too fast. The liver processes the fat into a fuel called ketones, which causes the blood to become acidic. Initial management is - 0.9% saline Treatment of choice - Insulin ...
Medicine
DNB 2018
c3738a59-7894-4e55-9854-efe08aedc855
All of the following are true regarding pilonidal sinus except: September 2009
Seen predominantly in women
Occurs only in sacrococcygeal region
tendency for recurrence
Obesity is a risk factor
0a
multi
Ans. A: Seen predominantly in women Pilonidal disease is described back as far as 1833, when Mayo described a hair-containing cyst located just below the coccyx. Hodge coined the term "pilonidal" from its Latin origins in 1880. Pilonidal disease describes a spectrum of clinical presentations, ranging from asymptomatic ...
Surgery
null
c17b05e7-6815-4b07-9917-72b3ab94ab9b
Fever & hemorrhagic rash are seen in ail except:
Dengu fever
Lassa fever
Rift Valley fever
Sand fly fever
3d
multi
Ans: D (Sand,.) [Ref: Ananthanarayan 8th/514.518-19; Harrison 18th/l50,1629; Medical microbiology by Greenwood 16 th /4961The viral HF syndrome is a constellation of findings based on vascular instability and decreased vascular integrity. An assault, direct or indirect, on the microvasculature leads to increased permea...
Microbiology
Virology
84aa7cd3-d2f6-49d4-a2cd-a1ab53324c85
Argentaffin cells in the GIT produce
Gastrin
Pepsin
HCl
None of the above
3d
multi
Their granules contain a chemical called serotonin, which stimulates smooth muscle contractions.
Anatomy
Systemic histology
3c372938-0d3a-43c0-a2ae-4e6d55a8f27f
A 46-year-old man has a swelling in the scrotum. It shows clear transillumination anterior to the testis when a light is applied to the scrotum in a dark room. This physical exam is most consistent with?
Cyst of the epididymis
Torsion of testis
Hydrocele
Direct inguinal hernia
2c
single
In adults, this is diagnostic, but in children, transillumination is also seen in an indirect inguinal hernia. As epididymal cyst may transilluminate but is posterior to the testis.
Surgery
Urethra & Penis
543b414e-7103-4b2b-91cc-5545926a9b7d
A 35-year patient recalls episodes where he smells a pungent odor, becomes sweaty and loses consciousness. His family member says while unconscious he was having facial twitching with lip-smacking movements. What is the most probable diagnosis?
Focal seizures
Hysteria
Atonic seizures
Myoclonic seizures
0a
multi
The patient is exhibiting focal seizures which are accompanied by transient impairment of patient's ability to maintain normal contact with environment. Chewing, lip smacking, swallowing or picking movements of hands are called Automatism. Full recovery after the episode range from seconds to an hour. Due to involvemen...
Medicine
Epilepsy and EEG