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543b141c-025d-4360-9e46-4f4f87894d9b | A cold nodule in thyroid scintiscan mean | Nodule which is cold | Hyperactive nodule | Nodule which is nonfunctioning & malignant | Nodule which has no signs of inflammation | 2c | single | null | Surgery | null |
4887adf2-a741-4aab-a401-5a0d9478e00a | Earliest sensation to be lost in Hansens disease is - | Pain | Touch | Vibration | Temperature | 1b | single | null | Social & Preventive Medicine | null |
d2a74fda-f991-467d-8048-9ff1b10a261c | Who said these words : To study the phenomenon of disease without books is to sail an unchaed sea, while to study books without patients is not to go to sea at all - | Hamilton Bailey | Sir Robe Hutchison | Sir William Osler | J.B. Murphy | 2c | multi | Ans. is 'c' i.e., Sir William Osler | Surgery | null |
bdd45e8b-7a10-45e2-97b2-14e955664bd7 | Which of the following contains highest protein content? | Triglycerides | HDL | LDL | VLDL | 1b | single | Ans. b (HDL). (Ref. Harper, Biochemistry, 25th ed., 268)PROPERTIES OF PLASMA LIPOPROTEINS LipoproteinMajor lipidElectrophoretic mobilityMajor apoproteinsProtein content1ChylomicronTriglycerideNoneB-48, A-I, IV-2Very low density (VLDL)TriglyceridePre-betaB-100, E, C-I, II, III-3intermediateTriglyceride & density (IDL)ch... | Biochemistry | Lipids |
c3fe911d-6ccd-4ad4-aaf0-4c1d19800f59 | During a football game a 21-year-old wide receiver was illegally blocked by a linebacker, who threw himself against the posterolateral aspect of the runner's left knee. As he lay on the ground, the wide receiver grasped his knee in obvious pain. Which of the following structures is frequently subject to injury from thi... | Fibular collateral ligament | Anterior cruciate ligament | Lateral meniscus and posterior cruciate ligament | Fibular collateral and posterior cruciate ligament | 1b | multi | This type of injury can result in the "unhappy triad" (of O'Donahue) injury, with damage to the medial collateral ligament (MCL), anterior cruciate ligament (ACL), and medial meniscus. A blow to the lateral side of the knee stretches and tears the MCL, which is attached to the medial meniscus. The ACL is tensed during ... | Anatomy | Lower Extremity |
d3dd46c1-b874-4b4d-a853-27b078da2259 | 23-year-old medical student complaint of feeling "worried." He fears failing his clinical exam because he feels nervous about presenting a case and performing physical examination in front of examiners. He would skip bedside teaching when it would be his turn to present a case in front of his classmates and tutors. He ... | Normal shyness | Panic disorder | Generalized anxiety disorder | Social phobia | 3d | single | Clinical picture of fearing presentation in public, avoidance, fear of criticism is suggestive of social phobia. It is also known as social anxiety disorder. In Generalised anxiety disorder there is free flowing anxiety at all time. In panic disorder there are recurrent panic attacks with feeling of impending doom. | Psychiatry | Neurotic, Stress Related and Somatoform Disorders |
c5f701a2-e5e4-41de-8ef1-5cda236f40b2 | A 1-year-old female infant is hospitalized for pneumonia. Bacterial cultures of the sputum have grown Pseudomonas aeruginosa. She has had two prior hospitalizations for severe respiratory infections. Her mother has noted that when she kisses her child, the child tastes "salty." The child has had weight loss that the mo... | Cystic fibrosis transmembrane conductance regulator | Dystrophin | a-1,4-Glucosidase | a-L-Iduronidase | 0a | multi | Cystic fibrosis, Most common lethal genetic disease in Caucasian populations. Defect in the cystic fibrosis transmembrane conductance regulator (CFTR) protein Deletion of phenylalanine in position 508 (DF508 mutation). Affected patients often have multiple pulmonary infections and pancreatic insufficiency with steatorr... | Pathology | Genetics |
c6a5483b-d9e5-4748-96fd-db67312cb3f7 | Retinal output is mainly from | Ganglion cell layer | Layer of rods & cones | Outer nuclear layer | Outer plexiform layer | 0a | single | (A) Ganglion cell layer # Retina:> Layer of rods & cones: These are the end organs of vision & are also known as photoreceptors> Outer nuclear layer: It consists of nuclei of the rods and cones.> Outer plexiform layer: It consists of connections of rod spherules and cone pedicles with the dendrites of bipolar cells and... | Medicine | Miscellaneous |
02e3ddc6-35ef-4482-8e3a-ac4b9603597f | Global warming, which is true: | CO2 is the major green house gas | Stratosphere ozone layer is harmful | CFC increases the zone of stratosphere | KYOTO protocol set the target of net reduction of 20 green house gas emission | 0a | multi | CO2 is the major green house gas | Social & Preventive Medicine | null |
a382164d-8b96-4ac4-933d-540b7968ca22 | Lathryism is due to - | Khesari dal | Aflatoxins | Aspergillus | Fluoride | 0a | single | Ans. is 'a' i.e., Khesari Dal Lathvrismo Lathyrism is caused bv lathyrus sativus, commonly known as "Khesari dhal"o The toxin present in lathyrus seeds has been identified as Beta oxalyl aminoalanine (BOAA).o Toxin is water soluble,, this property has been made use of in removing the toxin from the pulse by soaking it ... | Social & Preventive Medicine | Nutrition and Health |
39f4b565-9218-4de0-8aca-f48fcfc406ad | Bone tumors arising from diaphysis -a) Chondrosarcomab) Ewing's tumorc) Osteoclastomad) Chondroblastoma e) Osteid osteoma | ab | ad | bc | be | 3d | single | Diaphyseal lesions : - Ewing sarcoma, Lymphomas, Fibrous dysplasia, Adamantinoma, Histiocytosis, Osteoid osteoma, Chondromyxoid fibroma, Fibrosarcoma, Fibrous cortical defect. Non ossifying fibroma | Orthopaedics | null |
bf51a57c-7701-4b35-824d-64d0798e4a94 | Vitamin K dependent clotting factor is | VII | I | XI | XII | 0a | single | Vitamin K dependent clotting factors (VKCF) are clotting factors II (prothrombin), VII (Proconvertin), IX (Christmas factor), X (Stuart Prover Factor), protein C, protein S and protein Z. | Biochemistry | null |
4a269911-3efa-4b4f-aea0-1d096a841670 | IPC code related to age for valid consent is? | 85 | 86 | 87 | 88 | 2c | single | Ans. is 'c' i.e., 87o Section 87 of the IPC says that a person above 18 years of age can give valid consent and Section 89 of the IPC says that a child under 12 years of age cannot give a valid consent.Other optionso 85 and 86 I PCs are related to drunkenness and criminal responsibility.o 88 IPC: Act not intended to ca... | Forensic Medicine | Introduction to Forensic Medicine and Medical Jurisprudence |
383948b7-bbde-4c78-b992-e507c6a9fa27 | A patient of 40 years male got a blow on the angle region of mandible and he is asymptomatic. The x-rays of that region shows a radiopaque line with very sharp undercut in the lower border of mandible which may be due to: | Sutural diastasis | Overlapping sign | Separation sign | Non union sign | 1b | single | null | Surgery | null |
ca06d177-cb7e-4b41-be31-1bbb70024a84 | The dose of Dopamine used for renal vasodilatation is? | 2.5 ug/kg/min | 5-10 ug/kg/min | 10-20 ug/kg/min | 1-2 ug/kg/min | 3d | single | Dopamine is used in the treatment of shock - cardiogenic, hypovolemic, and septic shock. It is especially useful when there is renal dysfunction and low cardiac output because dopamine increases renal blood flow and thereby GFR. Dopamine stimulates the hea - increases FOC, CO, BP. It is also sho acting. Its dose is 2-5... | Pharmacology | Autonomic nervous system |
22492e18-1b16-4b47-9535-29e29360ac8a | Smokeless Gun powder contains | Nitrocellulose | Charcoal | Potassium | Sulphur | 0a | single | SMOKELESS gun powder: Single base: Nitrocellulose Double base: Nitrocellulose + Nitro-glycerine Triple base: Nitrocellulose + Nitroglycerine + Nitroguanidine | Forensic Medicine | Ballistics |
50e3bd81-d9f2-4f65-90cb-e2200388cfaf | What is the content of ethinyl estradiol in very low dose oral contraceptives ? | 30 pig | 25 ps | 20ug | 151.tg | 2c | single | Ans. is 'c' i.e., 20 jutg o Very low dose OCPs ---> 20 mg ethinyl estradiol. o Conventional OCPs --> 30-50 mg ethinyl estradiol (mostly 30 g) | Social & Preventive Medicine | null |
cc763197-f7c6-4eb8-b8c4-6cb5a8fc46e7 | True statement about widal test in typhoid is-( | Widal test is confirmative in endemic areas | Antibiotic treatment does not alter widal test results | Previous infection alters widal test | Widal test does not alter with prior vaccination | 2c | multi | Ans. is 'c' i.e., Previous infection alters widal test . Person who have had prior infection or immunization may develop an anamnestic response during unrelated fever and may show false positive reaction. This may be differentiated by repetition of test after a week. The anamnestic response shows only a transient rise,... | Microbiology | null |
ad5476c5-846a-4e03-92aa-21de351fe700 | Schizophrenia mostly occurs in - | Adolescents | Children | Middle age | Old age | 0a | single | Schizophrenia starts in late adolescence and early adulthood (15-20 years). | Psychiatry | null |
c5bd1350-d0c4-4af3-af0a-dbb5e1f8ac06 | ECG of a patient with snake bite is shown below. What is the abnormality seen? | Hyperkalemia | Hypokalemia | Myocarditis | Bigemini | 0a | single | ECG changes typically occur when serum potassium is < 3 mEq/L, and include ST segment sagging, T wave depression, and U wave elevation. With marked hypokalemia, the T wave becomes progressively smaller and the U wave becomes increasingly larger . Ref Davidson 23rd edition pg 370 | Medicine | Fluid and electrolytes |
f200b6b4-21bc-4c16-af08-f0b0d01cf944 | The following condition is treated with | Systemic antifungal therapy | Systemic antiviral therapy | Systemic corticosteroids | Systemic antibiotics | 2c | single | The picture and the description are characteristic features of Pyostomatitis vegetans . It is usually treated by corticosteroids | Pathology | null |
493fcd5d-a3d7-42a1-a531-98cd155e1412 | A 72-year-old woman presents with bone pain and tenderness in her lower extremities and left clavicle. Physical examination reveals tenderness to palpation on her lower legs and left midclavicle. Laboratory studies reveal elevated calcium, decreased phosphate, and elevated parathyroid hormone (PTH). X-ray reveals the f... | Paget disease of the bone | Osteomalacia | Osteoporosis | Osteitis fibrosa cystica | 3d | single | Ans. (d) Osteitis fibrosa cystica.The patient in this question has hyperparathyroidism (elevated PTH) and is showing clinical symptoms for osteitis fibrosa cystica, a disease in which cystic bone spaces are filled with brown fibrous tissue. This disease is associated with hyperparathyroidism because PTH first acts on o... | Orthopaedics | Hyperparathyroidism |
f7573eda-70b1-4f8e-9ad6-633f7af9df9e | For the immediately life-threatening injuries of the chest "Laryngeal obstruction", select the proper intervention. (SELECT 1 INTERVENTION) | Endotracheal intubation | Cricothyroidotomy | Subxiphoid window | Tube thoracostomy | 1b | single | Airway obstruction denotes partial or complete occlusion of the tracheobronchial tree by foreign bodies, secretions, or crush injuries of the upper respiratory tract. Patients may present with symptoms ranging from cough and mild dyspnea to stridor and hypoxic cardiac arrest. An initial effort should be made to digital... | Surgery | Trauma |
da047165-1bc5-42a3-a9e7-cf51843daa75 | All of the following conditions are associated with systolic thrill in left 2nd and 3rd intercostal space, EXCEPT: | Pink TOF | Subpulmonic VSD | Pulmonic stenosis | Ebstein's anomaly | 0a | multi | Pink TOF is not commonly associated with a left upper parasternal systolic thrill. It is associated with a systolic thrill in second and third intercostal space. The physiology of TOF depends primarily on the severity of pulmonary stenosis and on the size of the VSD. Pink TOF is said to occur in patients with a large V... | Medicine | null |
59bf6216-151b-4e33-b1e2-1b29748e9fd9 | Which of the following is not example of Pseudopubey? | Tumor of hypothalamus | Ovarian tumor | Tumor of adrenal gland | All of above | 3d | multi | Ans. is 'd' i.e., All of above | Pediatrics | null |
aefae278-4d5e-4b1b-bcbf-f304a7a4cad7 | Angiogenesis is | Formation of the new blood vessels | Repair by connective tissues | Formation of the blood clot | All of the above | 0a | multi | (Formation of the new blood vessels) (71-72-R) (70-72- Basic pathology 8th)ANGIOGENESIS or neovascularization by which preexisting vessels send out capillary sprouts to produce new vessels.Angiotensis is a critical process in the healing at sites of injury in the development of collateral circulations at sites of ische... | Pathology | Blood Vessels |
d26f2b15-ca73-44ed-a7c6-ba1eb8f16c3a | In Cushing syndrome, which of the following are seen - | |Aldosterone | |Aldosterone | |Epinephrine | |norEpinephrine | 0a | single | Cushing syndrome is a disorder resulting from increased adrenocoical secretion of coisol, due to any one of several sources: ACTH-dependent adrenocoical hyperplasia or tumor, ectopic ACTH-secreting tumor, or excessive administrations of steroids; characterized by truncal obesity, moon face, acne, abdominal striae, hype... | Physiology | Endocrinology |
7d3d2faf-63b7-4dc9-8f00-07017a1d0213 | True about chancroid is | Incubation period is 3 to 10 weeks. | Characterised typically by prodromal symptoms and systemic reaction. | Painful ulcer with irregular erythematous non-indurated margins. | Ulcer base is hard, indurated. | 2c | multi | Chancroid:
Incubation period = 3 to 10 days
It lacks systemic reaction and prodrome.
Ulcer base is soft. | Gynaecology & Obstetrics | null |
ee776915-2a77-4fcc-a515-dc5221cd3ea1 | Highest level of health care is | Primary health care | Tertiary care | Child care | Secondary level care | 1b | single | null | Social & Preventive Medicine | null |
44797cd6-43bc-4f0e-966a-28785d2d9a54 | All the following muscles are supplied by Anterior division of Obturator Nerve except | Pectineus | Adductor Longus | Gracilis | Adductor Magnus | 3d | multi | The main nerve supply to muscles of the adductor compament is the obturator nerve. The adductor longus and the gracilis are supplied by the anterior division of this nerve. The adductor brevis is supplied by the anterior division or by the posterior division. The adductor magnus has a double nerve supply. Its adductor ... | Anatomy | Lower limb |
6ca3d5c3-6a99-4011-a0f5-b3a923f44569 | Pedigree analysis – Analyze the following pedigree and give the mode of inheritance – | Autosomal recessive | Autosomal dominant | Mitochondrial inheritance | X linked dominant | 2c | single | This pedigree chart has the following two characteristics: -
The disease is manifesting in both males and females.
But, the disease is transmitting to the next generation only by females (mother).
Both these are characteristics of mitochondrial diseases.
Mitochondrial diseases
Mitochondrial DNA is the only non-... | Pediatrics | null |
df3d5830-ab1b-4552-a792-7fdcb57a5393 | Gracey curettes are area specific instruments because: | They are used in the specific areas of the US | They adapt to specific areas of the tooth or root | They have more than one angle per cutting edge | They are used for root planning | 1b | single | null | Dental | null |
3137698f-4b1f-45f8-9701-97d2969262ca | Suspended animation may be seen with : | Electrocution | Strangulation / hanging | Drowning | Burn | 0a | single | A i.e. Electrocution Suspended animation (i.e. apparent death) is seen in electrocution & apparently drowned (not drowning)Q | Forensic Medicine | null |
ac7debce-c420-47f2-ac55-0fc8398f0f3a | A young man underwent surgery for the removal of Glomus tumor. Glomus tumor is seen commonly in: | Liver | Adrenals | Pituitary | Finger | 3d | single | Glomus tumor is a benign soft-tissue extremity tumors, these lesions arise from dermal neuro myo aerial apparatus (glomus bodies). Glomus tumor more commonly affects the hand. In addition to the severe pain, point tenderness and cold sensitivity are associated with these lesions and subungual glomus tumors typically ap... | Surgery | null |
ca68969c-14af-437d-8cdb-82fbfade7c4e | Not a manifestation of anaphylactic shock: CMC (Ludhiana) 11 | Hypotension | Vasoconstriction | Bronchospasm | Laryngeal edema | 1b | single | Ans. Vasoconstriction | Forensic Medicine | null |
9084586c-edaa-42c5-ac06-b9fe8c5a2c52 | TOF - include all except ? | Pulmonary stenosis | VSD | ASD | RVH | 2c | multi | Ans. is 'c' i.e., ASD Tetrologv of 'allot Cyanotic hea disease (MC). Defect in infundibular septum leads to : Pulmonary stenosis. VSD (Not ASD) Dextroposition and overriding of aoa. Right ventricular hyperophy (NOT LVH). Pink TOF (Acyanotic TOE) when PS is mild to moderate balanced shunt tnt across the VSD, pt not have... | Pediatrics | null |
4aaa1c7a-f8cb-417b-a4bd-30ad0afb04ba | Which of the following is a MDG ? | Reduce by 2/3" the tinder five moality by year 1990-2015 | Halve the prevalence of HIV-AIDS by 2015 | Reduce maternal moality by 50% | Combat PEM & diarrhoea | 0a | single | Ans. is `a' i.e., Reduce by 2/3" the under five moality by year 1990-2015 | Social & Preventive Medicine | null |
59f63253-8911-4deb-a386-a6bc11fa2488 | The blood supply of the Jejunum is through the- | Inferior mesenteric artery | Superior mesenteric artery | Pancreatico duodenal artery | Ileocolic artery | 1b | single | Ans. B. Superior mesenteric arteryArterial supply to the gastrointestinal tract:-a. The arterial supply to the gastrointestinal tract is derived from the anterior midline visceral branches of the aorta. There are usually three anterior branches, the coeliac trunk and the superior and inferior mesenteric arteries. Varia... | Anatomy | Blood Vessels of Abdomen and Pelvis |
5f276bd3-64f5-4c53-ade1-b0b2834ba3cc | Good prognosis in schizophrenia is indicated by: | Soft neurological signs | Affective symptoms | Emotional Blunting | Insidious onset | 1b | single | Good Prognostic Factors Poor Prognostic Factors (1) Late Onset (1) Younger age of onset (2) Catatonic features (2) Disorganized type (3)Pyknic Built (3) Asthenic built (4) No Family history (4) Family history present (5)Acute onset 5) Chronic type (6) Emotions are preserved (6) Blunting of affect or atypical Feature Pr... | Psychiatry | null |
94ebeb17-c3b1-4be2-afd9-d615160485b1 | In rabies pathological lesions in CNS are - | Brainstem encephalitis | Cranial nerve arteritis | Neuronal loss | Neurofibrillary tangles | 0a | single | Rabies is a severe encephalitis, mainly involves.
Rhombencephalon ( rain stem - midbrain and the floor of the fourth ventricle in the medulla).
Basal ganglia
Spinal cord
Dorsal root ganglion. | Pathology | null |
b91ee142-66c1-405c-9c3f-47c450995652 | Color of postmoem lividity in hypothermic deaths: NEET 13 | Purple | Deep red | Cherry red | Bright pink | 3d | single | Ans. Bright pink | Forensic Medicine | null |
1006257b-c0b6-4b98-b4d3-b97dac082fab | Clozapine was the first antipsychotic drug. Which of the following is an indication for the use of Clozapine? | Resistant schizophrenia | Akathesia | First drug to be used for schizpophrenia | Used for schizophrenia with depression | 0a | single | Clozapine has been approved for, Patients with schizophrenia who have failed to respond adequately to typical neuroleptic drugs (treatment-resistant schizophrenia) Patients who are intolerant of typical neuroleptic drugs because of EPS or tardive dyskinesia Patients who are at high risk for suicide Ref: Meltzer H.Y., B... | Psychiatry | null |
d51af7b6-faa2-4abe-971a-b6b2ab12d46b | All of the following are nonselective beta blockers with additional actions except - | Carvedilol | Betoxalol | Caeolol | Labetolol | 1b | multi | Ans. is 'b' i.e., Betoxalol | Pharmacology | null |
a2c82225-4b8e-4ceb-8770-adeff7cefafc | Facial nerve palsy is seen in the following fracture | Anterior cranial fossa | Middle cranial fossa | Cranial vault | Posterior cranial Fossa | 1b | single | null | Surgery | null |
56206226-b0f9-43f1-9d90-d76b77757a1f | MIC-2 is a marker of- | Ewing's sarcoma | Osteosarcoma | Dermatofibrous protruberans | Alveolar cell sarcoma | 0a | single | Ans. is 'a' i.e., Ewing's Sarcoma o MIC 2 (CD 99) is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. | Pathology | null |
ffc86f0a-271c-4df4-9a30-e0fff74972dd | Type of speech seen in nasopharyngeal carcinoma - | Rhinolalia clausa | Rhinolalia aperta | Hot potato voice | Hoarse voice | 0a | single | Nasopharyngeal carcinoma causes denasal speech, i.e. Rhinolalia clausa. | ENT | null |
bea38473-5b3f-4bcb-b990-b86112d3bed2 | Cirsoid aneurysms most commonly occur in which of the following vessels? | Aoic arch | Splenic aery | Saphenous vein | Superficial temporal aery | 3d | single | Cirsoid aneurysms are rare aeriovenous malformations of the scalp and extremities. Cirsoid aneurysms of the scalp are fed by the superficial temporal aery | Surgery | Cardio thoracic surgery |
239083f1-487c-4a72-838a-1e416548e2fa | Sinuses are not seen in - | Kidney | Spleen | Endocrine gland | Liver | 0a | single | A i.e. Kidney | Anatomy | null |
678e6f66-4d6a-4934-9a92-73fba01fb004 | Most common pattern of Penumonia seen in Klebsiella infection is | Lobar Pneumonia | Bronchopneumonia | Interstitial Pneumonia | Miliary Pneumonia | 0a | single | Ans. is 'a' i.e., Lobar Pneumonia | Medicine | null |
10da5a5c-047a-4a45-aa1b-40d9d5781591 | ApoE, ApoC is synthesized by ? | Liver | Kidney | Intestine | RBCs | 0a | single | Liver Site of synthesisLiver & intestine A-I ,Liver A-V , B-00, C (C-I, C-11, C-III), EIntestine A-IV, B-48Spleen, brain, testes adrenal --> A- D | Biochemistry | null |
871df950-34b1-439c-b451-9a627e646c55 | A 40 year old woman is on treatment for CLL. Over the past few months she noticed swellings in the neck and axilla which was rapidly increasing in size. She complains of feeling feverish and experiences weight loss. Which of the following is responsible? | Richter transformation | Progression of CLL | Development of secondary infections | Immunodeficiency associated hemolytic anemia | 0a | single | CLL: Chronic Lymphocytic leukemia (CLL):- Neoplastic proliferation of native B cell; . Transformation to diffuse large B cell Lymphoma is marked by enlarging lymph node or spleen and worsening of symptom. This phenomenon is called Ritcher Transformation. Dx by flow cytometry positive for CD19/20, CD 5/23 Tx: Fludarabin... | Pathology | Chronic Lymphocytic Leukemia |
da1bcc2f-d0e5-43e4-bc4d-5fb583522a60 | Recurrent oral ulcers with pain and erythematous halo around them, diagnosis is – | Apthous ulcer | Herpes | Chicken pox | Measels | 0a | single | Recurrent oral ulcers with erythematous halos suggest the diagnosis of Aphthous ulcer. | Dental | null |
f6c5860a-1cad-4e08-9941-cc15095d6dc0 | Following changes are true about pregnancy, EXCEPT: | Blood volume maximum at 36 weeks | Cardiac output maximum at 30 weeks | Ureter dilates maximum in middle pregnancy | Serum cholesterol is maximum at 32 weeks | 0a | multi | The blood volume stas to increase from about 6th week,expands rapidly thereafter to maximum 40-50% above the nonpregnant level at 30-32 weeks. The cardiac output stas to increase from 5th week of pregnancy,reaches its peak 40-50% at about 30-34 weeks. Serum LDL and Cholesterol will reach a maximum of 260 mg/100 ml at n... | Gynaecology & Obstetrics | null |
d55b85d6-b5b0-4049-ac05-239d780a8097 | Which of the following is approved for the treatment of cystic fibrosis with G551D mutation? | Biostrophin | Peginesatide | Lumacaftor | Ivacaftor | 3d | single | Biostrophin is a vehicle for gene therapy in Duchenne and Becker's muscular dystrophyPeginesatide is an erythropoietin analog for anemia of chronic kidney diseaseLumacaftor is a CFTR potentiator for cystic fibrosis with F508 mutationIvacaftor is a CFTR potentiator for cystic fibrosis with G551D mutation | Microbiology | All India exam |
1cf2e045-7ce8-4400-935b-4b418ad386fe | Cortical blindness | Normal pupillary light reflexes with complete visual loss | Increased pupillary light reflexes with complete visual loss | Normal pupillary light reflex with partial loss of sight | Increased pupillary light reflexes with partial loss of sight | 0a | single | A. i.e. (Normal pupillary light reflexes with complete visual loss) (306 - Khurana 4th)CORTICAL BLINDNESS* Most common cause is bilateral occipital lobe infarction* Unilateral infarction leads to contralateral homonymous congruous hemianopiaClinical features* Vision and visual fields are markedly decreased* Sparing of ... | Ophthalmology | Neuro-Ophthalmology |
d6f97ab8-4c2c-4f77-9990-8a7420dd1651 | AML with worst prognosis - | 8/12 translocation | Inversion 16 | Normal cytogenetics | Monosomy 7 | 3d | single | null | Pathology | null |
d69eaf10-2504-4ae6-b952-3b8b7feacb4e | Biological amnesia is - | Lack of interest | Presenile dementia | Opioid addiction | Hypothyroidism | 1b | single | Biological amnesia:- Head injury (concussion/brain bruises), drugs (Marijuana, alcohol), brain disease (Korsokoff syndrome, Brain tumors, multiple sclerosis, presenile dementia), temporary disturbances in brain blood supply, and transient global amnesia.
Psychological amnesia :- Childhood amnesia, dream amnesia, defens... | Psychiatry | null |
69c73554-b26f-4569-b236-88493905cccb | A 25-year-old woman presents with symptoms of fatigue and weakness. On examination, there is diplopia, ptosis, weakness, and fatigability of muscles on repeated use. Which of the following is the most likely diagnosis? | myasthenia gravis | multiple sclerosis | TIAs | muscular dystrophy | 0a | single | The distribution of muscle weakness is characteristic with early involvement of the cranial nerves, especially the lids and extraocular muscles. Women are more frequently affected than men (3:2 ratio), and the age for peak incidence in women is in the third or fourth decade. | Medicine | C.N.S. |
4a5b4e2a-2737-431a-af68-1563f15c589a | Decompression of endolymphatic sac is the treatment for | Menier's disease | BPPV | Labyrinthitis | Otosclerosis | 0a | single | (A) (Meniere's disease) (104- Dhingra 6th)Surgical Treatment of Meniere's Disease1. Conservative procedures2. Destructive procedures3. IntermittentA. Decompression of Endolymphatic sacB. Endolymphatic shunt operationC. Sacculotomy (fick's operation)D. Section of vestibular nerveE. Ultrasonic destruction of vestibular l... | ENT | Ear |
9578f748-1e87-4ad9-be94-ceb7a674a204 | Subcostal nerve is - | Ventral rami of T6 | Dorsalrami of T6 | Ventralrami of T12 | Dorsalrami of T 12 | 2c | single | Ans. is 'c' i.e., Ventral rami of T12 o Ventral rami of upper 11th thoracic spinal nerves are known as intercostal nerves and ventral ramus of T12 is known as subcostal nerve.o Upper six intercostal nerves supply thoracic wall whereas lower five intercostal nerves and subcostal nerve supply thoracic and anterior abdomi... | Anatomy | Thorax |
59c75220-9b11-48e3-afb7-684f88ec8d33 | Progesterone is added to estrogens in H to achieve wof effects | Decrease the estrogen action on the breast | Decrease the occurrence of endometrial cancers | Increase the effectiveness of the estrogens | Inhibit bone resorption | 1b | single | Hormone replacement therapy (H) In nonhysterectomised postmenopausal women estrogen therapy is supplemented with a progestin for 10-12 days each month to counteract the risk of inducing endometrial carcinoma. Ref:- kd tripathi; pg num:-318 | Pharmacology | Endocrinology |
03bf9390-59fb-47e7-83c3-64e0d668b0d4 | Sedation as an adverse effect is MOST with which of the following atypical antipsychotics? | Risperidone | Olanzapine | Quetiapine | Aripiprazole | 2c | single | null | Psychiatry | null |
71284d6b-d978-4521-acc9-bc21413cf691 | Which of these amino acids will migrate slowest to the anode end at the physiological pH? | Aspaic acid | Glycine | Lysine | Valine | 2c | single | At physiological pH basic aminoacid (positive charged a.a) will move slowest towards anode (positively charged electrode).Basic amino acids are: Arginine (Most basic), Lysine and Histidine (Weakly basic) | Biochemistry | null |
bccdebf3-a26b-44da-8de3-d2fd3649528e | Which of the following is a useful marker to detect autophagy in cells? | BAK | BAX | LC3 | BID | 2c | single | Autophagy ("self-eating") is the process in which the starved cell eats its own components in an attempt to reduce nutrient demand to match the supply. Some of the cell debris within the autophagic vacuoles may resist digestion and persist in the cytoplasm as membrane-bound residual bodies. An example of residual bodie... | Pathology | Apoptosis |
d6d6ce93-fa80-4059-8410-f2f4440170d1 | Non - union is a complication of : | Scaphoid | Colle's | Inter- trochanteric of hip | Supra condylor of the humerus | 0a | single | A i.e. Scaphoid Fracture Fracture head & neck femur, fracture body of talus and fractures through waist of scaphoid most commonly leads to nonunion and avascular necrosis due to poor blood supplyQ | Surgery | null |
665ac470-bde9-42b7-94ce-d937039c75c4 | A 3-day old baby feeds poorly, vomits on feeding. Urine Benedict's test is +ve. The reducing substance present in the urine is: | Glucose | Sucrose | Fructose | Galactose | 3d | single | Galactosemia: Classic galactosemia is caused by almost total deficiency of galactose-1-phosphate uridyltransferase. Severely deficient neonates present with vomiting, jaundice, and hepatomegaly on initiation of lactose-containing feedings. Renal Fanconi syndrome, cataracts of the ocular lens, hepatic cirrhosis, and sep... | Pediatrics | null |
e12cd6e4-8b01-47fa-89d7-265c244db3bf | A 9 year old child disturbs other people, is destructive, interferes when two people are talking, does not follow instructions and cannot wait for his turn while playing a game. He is likely to be suffering from: | Emotional disorders | Behavioral problems | No disorder | Attention deficit hyperactivity disorder | 3d | single | This child has symptoms of hyperactivity and impulsivity and the most likely diagnosis would be attention deficit hyperactivity disorder. Symptoms of ADHD: - Inattention - Hyperactivity - Impulsivity - Other symptoms- Destructive behavior, irritability, and aggression. | Psychiatry | Child Psychiatry |
9403dc8d-1ba1-49e6-8825-b177038d0b67 | Which of the following is a monovalent cation that can reverse a digitalis induced arrhythmia ? | Digibind antibodies | Lignocaine | Magnesium | Potassium | 3d | single | null | Pharmacology | null |
6a755468-08ab-4560-a198-7841c60a7c15 | Which of the following aery is not involved in the formation of Kiesselbach's plexus? | Anterior ethmoidal aery | Posterior ethmoidal aery | Greater palatine aery | Sphenopalatine aery | 1b | single | Kiesselbach's area or Little's area, is a region in the anteroinferior pa of the nasal septum, where four aeries anastomose to form a vascular plexus called Kiesselbach's plexus. The aeries which forms the plexus are: ? Anterior ethmoidal aery (from the ophthalmic aery) ? Sphenopalatine aery (from the maxillary aery) ?... | ENT | null |
2c7a8db3-7911-47b2-8d1f-59f675ac120d | Allergic bronchopulmonary aspergillosis is characterized by all EXCEPT | Bronchial asthma | Pleural effusion | Centra bronchiectasis | Not respond to steroid | 3d | multi | (Not respond to steroid) (241-CMDT-10) (1259-H17th)* High doses of prednisone for at least 2 months is treatment of choice"* ABPA occurs in atopic asthmatic (particularly glucocorticoid dependent) individuals of age 20-40 years and non asthmatic individuals eg cystic fibrosisDiagnostic criteria for Bronchopulmoanry-Asp... | Medicine | Respiratory |
19c1563d-b26b-4948-97d4-39158becef3f | Most powerful chain breaking antioxidant: | Vitamin C | Alpha - tocopherol | Catalase | Glutathione peroxidase | 1b | single | Alpha- tocopherol is most powerful chain breaking anti-oxidants. 2 Classes of antioxidants Chain breaking anti - oxidants : (They interfere with chain propagation) Alpha - tocopherol Beta - carotene Vitamin C Super oxide dismutase (SOD) Uric acid/Urate Polyphenols Preventive antioxidants: (They reduce the rate of chain... | Biochemistry | Miscellaneous |
90b750e1-c186-44cb-84b1-1cda994f6801 | Acute non-suppurative sialdenitis is seen in: | Acute bacterial sialadenitis | Mumps | Chronic bacterial sialadenitis | Necrotizing sialometaplasia | 1b | single | null | Pathology | null |
5e9ed470-12cd-4b13-a77c-3e8c8dda1daa | All of the following modalities can be used for in situ ablation of liver secondaries , except | Ultrasonic waves | Cryotherapy | Alcohol | Radio-frequency | 0a | multi | Ultra sonic waves are not described as a method of local Ablative therapy for liver secondaries Local ablative therapy for liver secondaries Crypotherapy Radio-frequency or microwave ablation Ethanol, acetic acid, chemotherapy, hot saline Ref: Sabiston 20th edition Pgno :1464-1465 | Anatomy | G.I.T |
d6900265-17e6-48b5-92d1-a828d156d917 | Predisposing factors of carcinoma endometrium are all EXCEPT | Obesity | Late menopause | Multiparity | Unopposed administration of estrogen | 2c | multi | (Multiparity) (573-74-Shaw's 14th)Multiparity is common in carcinoma cervix, while carcinoma of endometrium women are either nulliparous or of low parityPredisposing Factors in Carcinoma Endometrium* Peak incidence is 55-70 years* An Early menarche and late menopause is characteristic* Unopposed and unsupervised admini... | Gynaecology & Obstetrics | Miscellaneous (Gynae) |
d943a92c-d1c3-456b-90eb-78defc33aed7 | Vagal stimulation of the hea causes: | Increased hea rate | Increased R-R interval in ECG | Increased force of hea contraction | Increased cardiac output | 1b | single | Increased R-R interval in ECG Vagus is the parasympathetic supply to the hea. Its stimulation causes: - Decreased hea rate - Decreased force of hea contraction - Decreased cardiac output R-R interval is the time interval between consecutive hea beats in the electrocardiogram. So a decrease in hea rate increases the R-R... | Physiology | null |
031e44a5-b16c-4eb8-b82a-b6beff3efb5f | This surgical blade is used for | Minor surgical procedures | Suture removal | Abscess drainage | Abdominal incision | 1b | single | This is Number 12 surgical blade. It is used for suture removal. | Surgery | null |
4734fb95-2116-4921-a6d9-4d40090ef712 | Type of necrosis in pancreatitis ? | Fibrinoid | Coagulative | Fat | Caseous | 2c | single | Ans. is 'c' i.e., Fat Fat necrosis is seen most frequently in acute pancreatitis due to leakage of lipase. Fat necrosis Fat necrosis may be of two types : ? 1. Enzymatic fat necrosis This is due to action of lipase on adipose tissue. It occurs most frequently in acute pancreatitis due to leakage of lipase. Depending on... | Pathology | null |
a33179ad-9af1-4a36-8c24-55eb2aa3a4de | True about kinematic facebow are all, except | It locates the true (exact) centre of condylar rotation or transverse horizontal axis. | It is preferred in full mouth reconstruction. | It usually requires a fully adjustable articulator. | None of the above | 3d | multi | null | Dental | null |
ebbebcea-40e5-4371-aea2-063bf5cff0c7 | A post partial gastrectomy patient presents with neurological symptoms. Most probable diagnosis is: | Folic acid deficiency | Thiame deficiency | Vitamin B12 de fid ency | Iron deficiency | 2c | single | Ref: Bailey unci Love's Short Practice of Surgery 25th EditionExplanation:Postoperative complications of gastrectomyLeakage of the oesophagojejunostomy.Leakage from the duodenal stumpParaduodenal collectionsBiliary peritonitisThe presence of septic collections along with a very radical vascular dissection may lead to c... | Surgery | Postgastrectomy Complications |
05f98cd7-0ecf-4734-8a37-bab796921add | Which antineoplastic agent is an antifolate drug: | Methotrexate | Adriamycin | Vincristine | Cyclophosphamide | 0a | single | Methotrexate | Pharmacology | null |
a0f9b646-cc92-4fe5-9df8-351a1e4b8fa2 | A 38-year-old woman shows evidence of early cataracts, hair loss, atrophy of skin, osteoporosis, and accelerated atherosclerosis. This patient has most likely inherited mutations in both alleles of a gene that encodes which of the following types of intracellular proteins? | Deaminase | Helicase | Oxidase | Polymerase | 1b | multi | Helicase. Werner syndrome is a rare autosomal recessive disease characterized by early cataracts, hair loss, atrophy of the skin, osteoporosis, and accelerated atherosclerosis. Affected persons are also at risk for development of a variety of cancers. Unlike Hutchinson-Gilford progeria, patients with Werner syndrome ty... | Pathology | Cellular Pathology |
3cf70421-5d32-4072-a3d9-c903a111d3e1 | ER-positive status in Ca Breast indicates - | Prognosis | Etiology | Site | None | 0a | multi | Estrogen receptor (ER) positive breast carcinomas are generally slow-growing and respond well to hormonal treatment.
Gene expression profiling, which can measure the relative quantities of mRNA for essentially every gene, has identified five major patterns of gene expression in invasive ductal carcinoma.
1. Luminal A
... | Pathology | null |
2b0593b3-d3d7-45ea-b605-a6d7e8cf90a5 | Replacement & periodic examination in radiation industary is recommended ? | Every month | Every 2 months | Every 6 months | Every year | 1b | single | Ans. is 'b' i.e., Every 2 months Preventive measures in radiation industeriesInhalation, swallowing or direct contact with the skin should be avoided.In case of X-rays, shielding should be used of such thickness and of such material as to reduce the exposure below allowable exposures.The employees should be monitored a... | Social & Preventive Medicine | null |
ef0bd6aa-c74b-4356-bcfb-a6e37e2c7971 | HCV is - | Enveloped RNA | Nonenveloped RNA | Nonenveloped positive strand RNA | Enveloped negative strand RNA | 0a | multi | HCV is a 50-60 nm virus with a linear single stranded RNA genome enclosed within a core and surrounded by an envelope carrying glycoprotein spikes. REF:ANATHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:549 | Microbiology | Virology |
5b9fce8f-b048-4367-8f75-7a6d5e61f423 | In Hutchinson's triad in newborn child, what is not seen? | Interstitial keratitis | Notched incisors | Deafness | Cataracts | 3d | single | Cataracts REF: Harisson's 18`11 ed chapter 169 Hutchinson's triad is named after Sir Jonathan Hutchinson (1828-1913). It is a common pattern of presentation for congenital syphilis, and consists of three phenomena: interstitial keratitis, Hutchinson incisors, and eighth nerve deafness | Pediatrics | null |
c573307f-a883-49a9-8606-6fc0eb90bf82 | ERCP in pancratitis is done to know about – a) Gall stoneb) Associated cholangitisc) Ascitesd) Pancreatic divisume) Annular pancreas | abcd | abde | acde | ade | 1b | multi | ERCP can be used in pancreatitis to evaluate conditions which can predispose to pancreatitis (e.g. Gall stone, pancreatic divisum, annular pancreas) and associated biliary cholangitis. | Radiology | null |
6a70538e-84dc-4b2f-ac22-9f3d086912ed | A 63-year-old man becomes oliguric 2 days following an open cholecystectomy. Which of the following findings would suggest that prerenal ARF is a major factor in the etiology? | postural hypotension | fractional excretion of sodium is 3% | specific gravity is 1.012 | the urine sodium is 30 mEq/L | 0a | single | Although evidence of volume contraction cannot confirm prerenal ARF, as this can progress into intrinsic renal failure, it suggests that prerenal factors are contributing. In prerenal ARF, specific gravity is usually > 1.020 and sodium concentration is < 10 mmol/L. The fractional excretion of sodium relates sodium clea... | Medicine | Kidney |
6200c3c6-7943-4c38-bc10-a6fea4f305e8 | Grade III intraventricular hemorrhage is | Intraventricular hemorrhage alone | Hemorrhage limited to germinal matrix | Hemorrhage with ventricular dilatation | Parenchymal extension of hemorrhage | 2c | single | Grade I - Hemorrhage limited to the germinal matrix
Grade II - Intraventricular hemorrhage
Grade III - Hemorrhage with ventricular dilatation
Grade IV - Parenchymal extension of hemorrhage. | Gynaecology & Obstetrics | null |
c47fff66-a500-4de2-b22c-bda36d49ec30 | Motor protein in organ of corti - | Kinesin | Albumin | Dynein | Myosin | 3d | single | Ans. is 'd'i.e.. Myosin o The inner hair cells of organ of corti have 50-200 ciliated structure called stereocilia.o The top of each stereocilium is linked to the side of next adjacent higher stereocilium by means of a thin filamentous strucuture called the tip-link.o Mechanically gated ion channels are located at thes... | Physiology | Special Senses: Hearing and Equilibrium |
f12b9d8b-817b-4959-864e-6d7958f62f71 | In acute pulmonary embolism, the ECG finding may include all except | S1Q3T3 pattern | P. pulmonale | Sinus tachycardia | T-wave inversion in leads V1 to V4 | 2c | multi | The most frequently cited abnormality, in addition to sinus tachycardia, is the S1Q3T3 sign: an S wave in lead I, a Q wave in lead III, and an inveed T wave in lead III. This finding is relatively specific but insensitive. RV strain and ischemia cause the most common abnormality, T-wave inversion in leads V1 to V4.Ref:... | Medicine | All India exam |
db16bb23-bff4-4cb7-bd09-5c6ef652b29e | A baby assessed at 5 minutes after bih is found to be blue with irregular gasping respiration. Hea rate(HR) is 60 beats/min, and a grimace is seen with some flexion of extremities. The Apgar score for this newborn is _______ | 0 | 2 | 3 | 4 | 3d | single | In this baby: Color: Score 0 Hea rate, < 60 beats/min: score 1 Grimace: score 1 Some flexion of the extremities: score 1 Irregular respiration: Score 1 Thus total score is 4 APGAR SCORING SYSTEM: Appearance 0 points 1 point 2 points Appearance (Skin color) Blue/Pale Pink body, blue extremities Pink Pulse Absent <100 BP... | Pediatrics | New born infants |
3799807c-a2ee-499e-b67e-a1f5dbdd7e31 | Which of the following is true regarding Fluorescence? | Spontaneous illumination in dark | Release of longer wavelength light on absorbing light of shorter wavelength | Release of shorter wavelength light on absorbing light of longer wavelength | Continuous emission of lights of different wavelength | 1b | multi | Ans. b. Release of longer wavelength light on absorbing light of shorter wavelength (Ref: Tietz' Fundamentals of Clinical Chemistry 5/e p75; Lehninger 4/447; Harper 29/e p311)In Fluorescence, there is release of longer wavelength of light on absorbing light of shorter wavelength is seen.FluorescenceIt is the emission o... | Biochemistry | Miscellaneous (Bio-Chemistry) |
2bedfa2d-89e6-4b68-a66b-0a09e24d0121 | Which immunoglobulin acts as receptor on B cell? | Ig G | Ig A | Ig M | Ig D | 2c | single | Ig M REF: Jawetz's, Melnick, & Adelberg's Medical Microbiology, 24TH edition chapter 8. Immunology B-cell Receptor for Antigen: B cells express a form of IgM that is located on the cell surface. Cell surface IgM has the same antigen specificity as the secreted IgM antibody molecule. This is achieved by a differential R... | Microbiology | null |
6d12df2a-58a0-42b0-ab88-ab08f24f23f8 | All of the following statements are true about the disease where the following rash is noted except: | The causative agent is Parvovirus B19 | This disease also known as Roseola infantum | Reticulate lacy exanthem may be noted on the trunk and extremities | Clinical features are usually seen in healthy individuals | 1b | multi | Ans. B. This disease also known as Roseola infantumThe image depicts the characteristic slap cheek appearance seen in 5th Disease Synonym: Erythema infectiosumParvovirus B19 most classically causes erythema infectiosum (EI), a mild febrile illness with rash. It often occurs in outbreaks among school-aged children, alth... | Skin | Miscellaneous |
4fd176cf-a2a5-4375-90bb-f8b5e2c7789c | Antibody against tumor cells - | MHC-I | MHC-II | Anti viral | Differentiated antigen | 0a | single | null | Pathology | null |
2b2a67fe-eb47-44a8-98bd-74fc38f3e98d | Chest X-ray findings in tuberculosis associated with HIV are all except: September 2005 | Disseminated tuberculosis | Lupus vulgaris | Pleural effusion | Hilar lymphadenopathy | 1b | multi | Ans. B: Lupus vulgaris Lupus vulgaris is a cutaneous manifestation of tuberculosis. | Medicine | null |
0ea97814-61c9-437d-8b1f-3329f9c3ae64 | Clinical features of nasopharyngeal angiogibroma are -a) 3rd to 4th decadesb) Adolescent malec) Epistaxis and nasal obstruction are the cardinal symptomd) Radiotherapy is the Rx of choicee) Arises from posterior nasal cavity | bce | bc | acd | ace | 0a | single | NFA occurs in adolescent males.
Nasal obstruction and epistaxis are the most common presenting symptoms.
It arises in the posterior part of nasal cavity near the sphenopalatine foramen.
Treatment of choice is surgery. | ENT | null |
abc20001-ea11-4125-9424-fbc2227c1090 | Resistance to zidovudine develops due to- | Mutations at reverse transcriptase | Increased efflux of the drug from inside the cell | Increased metabolism of the drug | Decreased zidovudine 5 triphosphate formation | 0a | single | Ans. is 'a' i.e., Mutations at reverse transcriptase "Resistance to Zidovudine occurs by point mutation which alters reverse transcriptase enzyme. In the past when AZT was used alone, > 50% patients became nonresponsive to AZT within 1-2 years therapy due to growth of resistant mutants" - KDT | Pharmacology | null |
8f2472b9-84d1-4132-8d15-3aa051b8169a | The pulmonary function test done on this patient of asthma would be | Non-infarmative | Obstructive pattern | Restrictive pattern | Destructive pattern | 1b | single | The patient is having atopic asthma.Pulmonary function tests in asthma show an obstructive pattern with reduced FEV1,FEV1/FVC ratio.Reversibility is demonstrated by a >12% and 200 ml increase in FEV1 15 minutes after an inhaled sho acting beta2 agonist or in some patients by a 2 to 4 week trial of oral coicosteroids. R... | Medicine | Respiratory system |
da8ad635-0037-47a4-a762-fc15e38a3525 | Macrophages in nervous system is known as: | Schwann cells | Oligodendrocytes | Astrocytes | Microglia | 3d | single | Microglia are scavenger cells that resemble tissue macrophages and remove debris resulting from injury, infection, and disease (eg, multiple sclerosis, AIDS-related dementia, Parkinson disease, and Alzheimer disease). Microglia arise from macrophages outside of the nervous system and are physiologically and embryologic... | Physiology | null |
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