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135
626f70d0-17dc-4902-881a-3df61f210f06
Not true about experimental study -
Always prospective
Unethical to use in animal
Can not be double blinded in animal trials
Interim analysis is permitted
1b
multi
Ans. is 'b' i.e., Unethical to use in animal Experimental epidemiology (Epidemiological Experiments) Experimental epidemiology is also called trial. Broadly speaking, a trial refers to putting something to a test. This allows the term to be used in reference to a test of a treatment for the sick or a test of a preventi...
Social & Preventive Medicine
null
5995b0bf-e454-4917-ba81-2053a4a26cc4
Appearance of Breast bud is known as: March 2013
Menarche
Thelarche
Pubarche
Anarche
1b
single
Ans. B i.e. Thelarche Thelarche is the onset of secondary (postnatal) breast development, usually occurring at the beginning of pubey in girls.
Gynaecology & Obstetrics
null
3831c897-090e-48df-b5cb-fb5fde4010e8
A patient presents in emergency in shock, with a history off fleshy mass protruding from vagina with heavy bleeding PV. She had history of delivery at home 1 hour back by a health worker with a history of difficulty in placental removal and 'Uterine handling'. Most probable diagnosis is?
Atonic PPH
Uterine inversion
Fibroid polyp
Cervical tear
1b
single
Uterine inversion presents after excessive traction on cord for pulling out the placenta, which leads to paial or complete inversion of uterus. It is usually associated with PPH and may result in shock (hemorrhagic and neurogenic. However more common cause of moality is hemorrhagic) if treatment is delayed.
Gynaecology & Obstetrics
Labour - III
33887d76-cfe3-498f-a8bc-0e5f65f4abaa
A 60 kg man has haematocrit of 40%. His plasma volume would be approximately:
2.4 L
2.9 L
3.6 L
5.0 L
1b
single
Plasma volume = Total blood volume * (1 - Hematocrit) The total blood volume is about 8% of body weight Blood volume of 60 kg man = 0.08 * 60 = 4.8 L Plasma volume = total blood volume * (1-hematocrit) = 4.8 * (1-0.40) = 4.8 * 0.60 = 2.88 L Also, about 60% of the blood is plasma and 40% is RBCs Thus, plasma = 5% of bod...
Physiology
Body fluid compaments
cbb4c34d-a9db-42a3-8db3-8a9405117256
A 17-year-old patient is referred by his GP after presenting with periorbital oedema. The patient noticed the oedematous eyes 3 days ago, but repos feeling unwell since a throat infection 3 weeks ago with nausea and vomiting in the last week. A urine dipstick is positive for protein and blood while serum creatinine and...
Nephrotic syndrome
Nephritic syndrome
Post streptococcal GN
Von Grawitz tumour
2c
single
C. (post strep. GN). This patient is suffering from post-streptococcal glomerulonephritis (C), which forms pa of the nephritic syndrome consisting of haematuria (micro- or macroscopic), hypeension, proteinuria and oedema. In severe cases, oliguria and uraemia can also occur. Patients usually suffer form a streptococcal...
Surgery
null
dca0925a-bc24-4ace-abfd-48666fcbb607
A 45 year old male presents to OPD with acute abdominal pain. On examination it seems to have spread to retroperitoneal structure. Which of the following is most likely to get affected
Stomach
Transverse colon
Jejunum
Descending colon
3d
single
The descending colon is a retroperitoneal organ. The rest of the organs are surrounded by peritoneum. Other retroperitoneal organs are: - Pancreas, Duodenum, Ascending colon, Descending colon, Middle third of the rectum
Anatomy
Abdominal wall ,Inguinal and Femoral region
04c9d3ec-718e-4d4b-8504-9c19e065f0f3
If biochemical test gives the same reading of early sample on reputed testing, it is inferred that the measurement is-
Precise
Accurate
Specific
Sensitive
0a
single
. biochemical test gives the same reading of early sample on reputed testing, it is inferred that the measurement is-precise. ref:park&;s textbook ,22 nd edition,pg no 22
Social & Preventive Medicine
Screening
70b60f0c-4ae5-4144-b7e2-23d7dfcc4c64
Which of the following has highest electrophoretic mobility and least lipid content:
Chylomicrons
HDL
LDL
VLDL
1b
single
B i.e. HDL
Biochemistry
null
3bd16bdf-b7ea-460e-ae85-f8bf61e816c1
Which of the following NSAID does not having antiinflammatory activity?
Ketorolac
Diclofenac
Mefenamic acid
Acetaminophen
3d
single
All NSAIDs, including selective COX-2 inhibitors, are antipyretic, analgesic, and anti-inflammatory, with the exception of acetaminophen, which is antipyretic and analgesic but is largely devoid of anti-inflammatory activity. Ref: Grosser T., Smyth E. (2011). Chapter 34. Anti-inflammatory, Antipyretic, and Analgesic Ag...
Pharmacology
null
05a13819-0d45-443f-9829-cf990a68fd3d
Somatostatin is secreted by :
D-cell
A-cell
B-cell
Dl-cell
0a
single
Ans. is A D-cell (Ref Ganong, 20/e, p. 339). Delta cells secrete - somatostatin* Beta cells secrete - insulin* Alpha cells of pancreas - glucagon*
Medicine
Miscellaneous (Endocrinology)
cf73ca18-b3f3-49d1-baab-0b60e4f75a46
Lancefield classification based on:
M protein
Carbohydrate antigen
Cell wall peptidogglycan
T protein
1b
multi
Carbohydrate antigen
Microbiology
null
709abe55-9e4e-4429-89f4-a116bd3c4d64
Percentage of offspring affected by colour blindness when a healthy male and heterozygous female marry
0
25%
50%
100%
1b
single
null
Medicine
null
4d4a0a84-bf42-4320-b3ba-04d712b9105b
All of the following are associated with pathogenesis of acute hydrops fetalis except: September 2009
Hypoproteinemia
Anemia
Hypoplasia of placental tissue
Metabolic acidosis
2c
multi
Ans. C: Hypoplasia of Placental Tissue Several hypotheses regarding the pathophysiologic events that lead to fetal hydrops have been suggested. The basic mechanism for the formation of fetal hydrops is an imbalance of interstitial fluid production and the lymphatic return. The fetus is paicularly susceptible to interst...
Gynaecology & Obstetrics
null
d1fe97ca-cace-4717-9f8e-45b0058853e3
To provide anesthesia to a patient in the third stage of labor, an obstetrician palpates the ischial spine transvaginally, then injects a local anesthetic. Injection of anesthetic at this approximate location will most likely block which of the following nerves?
Inferior gluteal nerve
Lateral femoral cutaneous nerve
Obturator nerve
Pudendal nerve
3d
multi
The pudendal nerve is often anesthetized to provide obstetric anesthesia (although epidural blocks are now more commonly used in preparation for delivery). The pudendal nerve arises from sacral segments 2, 3, and 4. It exits the pelvis by way of the greater sciatic foramen and then courses around the ischial spine (and...
Anatomy
null
953629ea-6c74-4bf5-a94c-60bcb37c8394
Centrally acting antihypeensive drug is ?
Phenoxybenzamine
Methy ldopa
Propanolol
Prazosin
1b
multi
Ans. is 'b' i.e., Methyldopa o Centrally acting sympatholytic antihypeensives are clonidine, methyldopa, guanabenz, guanfacine, moxonidine and rilmenidine.
Pharmacology
null
64d7d805-c369-422b-af10-548cda6a1692
Cyanosis does not occur in severe anemia because
Hypoxia stimulates erythropoietin secretion
Oxygen carrying capacity of available Hb is increased
Critical concentration of Hb required to produce cyanosis is reduced
Oxygen Dissociation Curve shifts to right
2c
single
Because reduced Hb is purple, a low aerial O2 saturation causes cyanosis. However, this is not a reliable sign of mild desaturation because its recognition depends on so many variables, such as lighting conditions and skin pigmentation. Because it is the amount of reduced Hb that is impoant, cyanosis is often marked wh...
Physiology
Respiratory system
7e34cbba-ede9-4a14-bfd5-7765a5c630bb
Daily depressed mood for minimum ________ weeks is must to classify someone as suffering from major depression disease -
1
2
3
4
1b
single
Symptoms of depression should be present for at least 2 weeks.
Psychiatry
null
b3c7e831-adad-462b-b5fa-c5435bdc27e0
A person on fat free, carbohydrate-rich diet, continues to grow obese. Which lipoprotein is increased in this person's blood:
LDL
HDL
VLDL
Chylomicrons
2c
single
Carbohydrate-rich diet will lead to increase in Acetyl CoA production, which will lead to synthesis of fats in body. These fats are endogenous fat, which are transpoed in the form of VLDL. ADDITIONAL EDGE: When exogenous fat (fat directly from diet) is taken then it is transpoed in the form of chylomicrons. Atkin's die...
Biochemistry
Lipoproteins
92e76a23-a7a9-4b09-9670-3d0c956aa292
The following is part of Hamstrings -
Semimembranous
Gracilis
Short head of biceps femoris
Sartorius
0a
single
Ans. (a) SemimembranousRef.: BDC 6th ed. vol. II / 83* Hamstring muscles are - Semimembranosus, semiten- dinosus, long head of biceps femoris and ischial head of adductor magnus.
Anatomy
Posterior Compartment of Thigh & Popliteal Fossa
b763df11-ae18-41c5-97d1-fb467d47a94c
A 58-year-old man whom you have followed dies suddenly, spurring you into doing some research on sudden death. Which of the following is the most likely cause for this individual?
extensive coronary atherosclerosis
electrolyte disturbance
pulmonary embolism
acute stroke
0a
single
Sudden death, defined as death within 1 hour of onset of symptoms, is usually caused by cardiac disease in middle-aged and elderly patients, but in younger age groups noncardiac causes predominate. There is a bimodal distribution in the population, with the first peak before 6 months of age (sudden infant death syndrom...
Medicine
C.V.S.
2b815900-eb5e-4b39-b6e7-7d226deffadf
Laparoscopy is the diagnostic procedure of choice for: March 2008
Ca uterus
Ca cervix
Ca rectum
Endometriosis
3d
single
Ans. D: Endometriosis Indications for gynaecological laparoscopy include the following: Ovarian cysts and tumours. Removal of fibroids (Myomectomy).or destroying them (Myolysis) Infeility, lysis of adhesions. Infeility, checking the condition and patency of the fallopian tubes. Reproductive or tubal surgery Endometrios...
Gynaecology & Obstetrics
null
a4b465cc-3565-4939-b101-986f525a37df
All of the following brace are used in scoliosis except?
Milwaukee
Risser
Boston's
Minerva
3d
multi
Minerva cast is used in cervical spine
Orthopaedics
Fracture Management
4083d4b2-e584-4a18-9210-03a105af1b23
Regarding Natural Killer Cell, all are true except?
It is activated by IL-2
CD-56 positive
Antibody induced proliferation
Variant of large lymphocyte
2c
multi
Natural Killer Cells (or NK cells) are a type of cytotoxic lymphocyte critical to the innate immune  system. NK cells play is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response.   CD 56 and CD 16 positive. Special action against viruses and tumor cells.
Microbiology
null
0c5b688d-e720-4bc9-93dd-835ecdfd1611
Borders of Gastrinoma triangle are all except:
Cystic duct CBD junction
Duodenum 2nd and 3rd part junction
Tail of pancreas
Neck of pancreas
2c
multi
Ans. (c) Tail of pancreasRef: Sabiston 20th edition Page 952Passaro triangle* 70-90% Gastrinomas are located in this triangle
Surgery
Pancreas
1be04ec6-c0d7-46b3-aa82-57cc4a90e480
the most common pathology of acute renal failure ?
DPGN
RPGN
ATN
allergic interstitial nephritis
3d
multi
Acute renal failure (ARF) - acute kidney injury AK1 is a sudden and usually reversible loss of renal function which develops over days or weeks and is usually accompanied by a reduction in urine volume. - A rasied creatinine level can be due to acute, acute on chronic of chronic kidney disease. Treatment of Acute Renal...
Medicine
All India exam
5c9e07db-21ab-48df-8569-69f7b02438ee
Osteoclasts are inhibited / modified and regulated by:
Parathyroid hormone
Calcitonin
1,25 - dihydroxycholecalciferol
Tumour necrosis factor
1b
single
null
Physiology
null
0c7baec6-73c4-4e5f-9e3f-52fc37e89888
A farmer rearing sheep, presented with complaints of fever and weakness for the last one month. There is generalised lymphadenopathy. There was also associated hepatomegaly. Biopsy of liver showed non caseating granuloma. These are most likely due to infection with:
Yersinia pestis
Brucella Canis
Francisella tularensis
Brucella melitensis
3d
single
B. melitensis, which is the most common cause of symptomatic disease in humans and for which the main sources are sheep, goats, and camels. Overall, the presentation of brucellosis often fits one of three patterns: febrile illness that resembles typhoid but is less severe; fever and acute monoahritis, typically of the ...
Microbiology
null
5a7664b3-049f-4d92-b900-d80b1b3ec9f1
All of the following statements are true EXCEPT:
Cervix is lined by stratified squamous epithelium
Cervix is lined by transitional epithelium
It gets its blood supply from uterine artery
Vagina is lined by nonkeratinized stratified squamous epithelium.
1b
multi
Ans. B Cervix is lined by transitional epitheliumRef: Grays, 41sted. pg. 295* The epithelial lining of cervix is varied. Ectocervix is composed of non keratined stratified squamous epithelium and endocervix is composed of simple columnar epithelium.* Blood supply of cervix-descending cervical branch of uterine artery.E...
Anatomy
Abdomen & Pelvis
c7f073dd-a12e-4ba8-b1da-094ce36af0e3
Which of the following bacteria is known as Ebe Gaffky bacillus
Klebsiella
H. Aegypticus
Salmonella typhi
Corynebacterium
2c
single
Klebsiella Friedlander's bacilli H.Aegypticus Koch week's bacilli Salmonella typhi Ebe gaffky bacilli Corynebacterium Kleb- Loeffler bacilli
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
5a4727aa-cf71-4f1b-91ab-8ae0a87c1050
Which of the following condition is associated with meconium ileus?
Fibrocystic disease of pancreas
Liver aplasia
Cirrhosis of liver
Malnutrition
0a
single
Meconium ileus is a neonatal manifestation of cystic fibrosis (also known as fibrocystic disease of pancreas). In cystic fibrosis there is pancreatic enzyme deficiency and abnormal chloride secretion in the intestine that results in the production of viscous water- poor meconium. Meconium ileus results because of impac...
Surgery
null
44cd1462-2a78-4009-8a26-52c42dce3f01
A 78 year old male is admitted with chest pain. His ECG shows widespread ST depression in all leads except aVR which shows ST elevation. Whilst in ER, he passes melaena and on fuher questioning, gave history of altered bowel habit, weight loss and dark stools for 2-3 months. O/E he is pale, pulse rate is 115 bpm and BP...
Aggressive treatment with dual antiplatelets
Packed RBC transfusion
Nitrates to relieve ischemia
Beta blocker to slow hea rate and reduce ischaemia
1b
multi
Dx is NSTEMI : Type 2 MI (due to Anemia) Option A : No, as he is already having GI bleeding, so antiplatelet therapy is not given. Option B : Yes, packed RBC transfusion is useful for anemia component to | oxyhemoglobin. Option C : Nitrates are C/I if Systolic B.P <80 mm Hg Option D : He's already having hypotension & ...
Medicine
Emergency Clinical Scenario
2b64005c-7ac8-4bae-b674-6ecafd5eb113
Jumping genes are also known as
Plasmids
Oncogenes
Transposons
Introns
2c
single
Transposons are called as Jumping genes as they can jump from one chromosome locus to another.
Biochemistry
null
08e1d184-85ab-408b-ad64-200a7a65f5c3
Danbury tremors seen in which chronic poisoning
Arsenic
Lead
Mercury
Zinc
2c
single
Mercurial tremors The hands are first affected. There will be tremors of the hands called Danbury tremors. It may progress to lips, tongue, arms, and legs. The tremors are moderately coarse and intentional to sta with and are interspersed by jerky movements. The advanced condition is called hatter's shake or glass blow...
Anatomy
Poisoning
30021379-a757-45db-b3f0-a2f7ea7e8be8
Clara cells are found in :
Trachea
Bronchioles
Alveoli
Oesophagus
1b
single
Ans. is 'b' i.e. Bronchioles Different parts of the respiratory tracts have distinctive histological features :Clara cells are found in-bronchioles*Goblet cells are found in-Bronchi*Mucous gland are found in-Bronchi*Neuroendocrine cells-Bronchi*Mural cartilage-Bronchi*Part rich in secretory immuno globin-Bronchioles*Po...
Anatomy
Respiratory System (Histology)
85b52a7d-3c88-45a5-b2ac-fc58c517bc59
Break bone fever is cuased by -
Variola
Coxsackie
Arbovirus
Adenovirus
2c
single
Break bone fever is caused by the dengue virus. REF:<\p>ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.523
Microbiology
Virology
ae4c6c05-1a3c-4f1b-8b51-1f8961e015de
Non Palpable purpura is seen in A/E
H. S. Purpura
Drug induced vasculitis
Idiopathic thrombocyto penic purpura
Amyloid
0a
single
A i.e. H. S. Purpura
Skin
null
1f063a8d-7e29-477b-b82d-d4292ae2effb
Composition of Sodalime is: NaOH Ca(OH)2 KOH
4% 95% 1%
5`)/0 90`)/0 10/0
80% 20%
15% 84% 1%
1b
single
15% 84% 1%
Anaesthesia
null
5b961ce0-8af8-448a-b76d-df87a85e1308
The initial response to iron therapy in a child suffering from iron-deficiency anemia is
Reticulocytosis
Replacement of intracellular iron enzymes
Initial bone marrow response
Erythroid hyperplasia
1b
single
Response to iron therapy can be documented by an increase in reticulocytes 5-10 days after the initiation of iron therapy. The hemoglobin concentration increases by about 1 g/dL weekly until normal values are restored Replacement of intracellular iron enzymes Ref essential paediatrics op ghai 9e
Pediatrics
Hematology
45c30033-9655-476a-9f9f-6d39b3e2ca95
Which of the following drug can lead to given below condition
Vancamycin
Phenytoin
Valproate
Amiodarone
3d
single
Amiodarone can lead to bluish discolouration of skin, also called as "Blue man syndrome".
Pharmacology
null
b7b3ccaa-a55e-40ce-9bb5-85184c5dd8cf
Which drug is suitable for epilepsy related to a brain tumor?
Levetiracetam
Phenytoin
Carbamazepine
Phenobarbitone
0a
single
In epilepsy caused by brain tumor, agent of choice is those drugs that do not induce hepatic microsomal enzyme system. Drugs such as : Levetiracetam Topiramate Lamotrigine Valproic acid Lacosamide.
Medicine
Epilepsy and EEG
b95b8f46-1398-450c-8042-c960bbd99086
Butterfly rash is seen in
Systemic lupus erythematosus
Erythema marginatum
Lupus gulgaris
Erythema nodosum
0a
single
(A) Systemic lupus erythematosus # SLE:> Characteristic Malar (Butterfly) rash seen as fixed erythematous rash over the cheeks, & bridge of nose (photosensitive but scarring is absent) Patchy scalp hair loss is seen & Hair usually regrow in SLE (but not in DLE) Raynaud's phenomenon is present in 10%; Antibodies against...
Skin
Miscellaneous
302ed724-9880-4390-8930-65205f9ef125
Juxtaglomerular apparatus lies in relation to the following structure and have secretory function:
Proximal convoluted tubule
Ascending loop of Henle
Descending loop of Henle
Glomerulus
3d
single
At the point where the afferent aeriole enters the glomerulus and the efferent aeriole leaves it, the tubule of the nephron touches the aerioles of the glomerulus from which it arose. At this location, which marks the sta of the distal convolution, there is a modified region of tubular epithelium called the macula dens...
Physiology
null
0b8610fe-9649-46cf-ab76-798378070847
All of the following substances are added to the urine by means of tubular secretion, except
Potassium
Hydrogen ion
Urea
Creatinine
2c
multi
null
Medicine
null
af06fe1a-8466-479c-9419-c668fcd61632
Kerion is: March 2009
Viral infection
Fungal infection
Bacterial infection
Parasitic infection
1b
single
Ans. B: Fungal Infection Kerion is severe form of tinea capitis, in which well-circumscribed pas of the scalp are transformed into a painful, boggy, inflamed, confluent mass with loosened hair (easy pluckability), purulent folliculitis, crusting, often with lymphadenopathy It is commonly due to a zoophilic dermatophyte...
Skin
null
a250c266-37a4-4ceb-8f79-148c76c6d9e5
Burning sensation in middle finger Triceps Reflex is weak Slip disc?
C6-C7
C5-C6
C3-C4
C2-C3
0a
single
HERNIATED DISC B/W COMPRESSED NERVE ROOT DERMATOME AFFECTED MUSCLES AFFECTED MOVEMENT WEAKNESS NERVE AND REFLEX INVOLVED C6 and C7 C7 C7 middle finger Triceps wrist extensors extension of forearm extension of wrist radial nerve | triceps jerk
Anatomy
Back region
b460a831-6fd1-4de7-acb9-6a337d44e908
A 70-year-old patient with long-standing type 2 diabetes mellitus presents with complaints of pain in the left, ear with purulent drainage. On physical examination, the patient is afebrile. The pinna of the left ear is tender, and the external auditory canal is swollen and edematous. The white blood cell count is norma...
Pseudomonas aeruginosa
Streptococcus pneumoniae
Candida albicans
Haemophilus influenzae
0a
single
Ear pain and drainage in an elderly diabetic patient must raise concern about malignant external otitis. The swelling and inflammation of the external auditory meatus strongly suggest this diagnosis. This infection usually occurs in older, poorly controlled diabetics and is almost always caused by P aeruginosa. It can ...
Medicine
Infection
409a9551-1ff1-491a-9ff8-4310634ba642
The relation between current, electromotive forces and resistance in a circuit by Ohm's law is stated as
i = E/R
i = R/E
i = RE
All of the above
0a
multi
Ohm’s law For electric current flow i = E/R For blood flow Q= ΔP/R
Physiology
null
3bb022c9-6529-4eb1-8ad3-4112c250ecf0
Commonest site of intro peritoneal abscess is
Lesser sac
Greater sac
Pelvis
None of the above
2c
multi
Pelvic abscess in the most common site of intra peritoneal abscess.
Surgery
null
ec1bd09d-b14d-4343-9e88-7b1da86e4057
Autotrophic requirements are
CO2 as a carbon source
NH3 as a nitrogen source
CO2 and NH3 together
Essential molecules that the bacteria are unable to synthesize
0a
single
Nutrients in growth media must contain all the elements necessary for the biosynthesis of pathogenic microorganisms. This rule is especially true of media that are intended to have a selective (select for a specific group of bacteria) or differential (differentiate between a pathogenic and a normal or usual strain of a...
Microbiology
general microbiology
b9afc7c1-e5aa-4107-8fab-becad4c77ab7
Down regulation of hormone means ?
Decreased secretion of hormone
Decreased affinity to receptors
Defective regulation in secretion
Regulation by low concentration of hormone
1b
single
Ans. is 'b' i.e., Decreased affinity to receptors Down regulation is a mechanism in which a hormone decrease the number or affinity of its receptors in target tissues. Down-regulation may occur by decreasing the synthesis of new receptors, by increasing the degradation of existing receptors or by inactivating receptors...
Physiology
null
09fb819a-e59e-454e-9194-626254c3f389
Blood-testis barrier is formed by
Seoli cells
Leydig cells
Epididymis
Vas deferens
0a
single
The name "blood-testis barrier" is misleading in that it is not a blood-organ barrier in a strict sense, but is formed between Seoli cells of the seminiferous tubule and as such isolates the fuher developed stages of germ cells from the blood. imageref-sciencedirect.com
Anatomy
Abdomen and pelvis
663434d1-4d6a-41b9-9644-f0d5e1fe645c
Foam cells are formed by?
Neutrophills
Fibroblasts
Macrophages
All of them
2c
multi
Ans. is 'c' i.e., Macrophages * Foam cells are lipid-laden cells that derive predominantly from macrophages (M2 type), but smooth muscle cells can also imbibe lipid to become foam cells.* They are seen in atherosclerosis.
Pathology
Misc.
3257f3d5-6e98-4ea1-ac9a-f16d6fd8ffa7
All are features of hypernatremia, except -
Convulsion
Elevated intracranial tension
Periodic paralysis
Muscle twitching
2c
multi
null
Medicine
null
19be49bf-8ba5-4a4a-bf30-e1ab6e1cb9c5
Least common complication of lead poisoning in adults -
Abdominal colic
Peripheral neuropathy
Anemia
Encephalopathy
1b
single
Among the given options, peripheral neuropathy is least common, and occurs in less than 10% of cases.
Forensic Medicine
null
25c2f0bc-73d9-4a63-b711-e92e67d7b356
The partial pressure of CO2 is lowest in:
Arterial blood
End tidal air
Expired air
Venous blood
1b
single
Ref: Multiple sources, Guyton, 12th edition, Pages 487- 488. 502-503: Khurana, W F Ganong, Review of Medical Physiology, 23rd edition Explanation: Normal PO2 and PCO2 at various sites Atmosphere (sea level) (inspired air Alveoli Pulmonary vein Arterial blood Tissue Venous Pulmonary artery Etpurid Air pO2 160 149-160 10...
Unknown
null
0751c48e-c165-4dbc-b34e-82463ca940f2
Testicular tumour can simulate ?
Hydrocele
Scrotum
Acute epidydimo orchitis
Chronic orchitis
1b
single
Ans. is 'b' i.e., Scrotum
Surgery
null
7048731d-babb-4d3e-b973-ef3cd8d5f832
A 12 years old boy presents with recurrent attacks of conjunctivitis for the last 2 years with intense itching and ropy discharge. The diagnosis is –
Vernal conjunctivitis
Phlyctenular conjunctivitis
Trachoma
Viral conjunctivitis
0a
single
Recurrent conjunctivitis, intense itching and ropy discharge in a 12 year old boy suggest the diagnosis of spring catarrh.
Ophthalmology
null
cbb4b21d-d4e7-4ddb-ade3-15797a79cc8f
Which type diabetes is HLA associated -
Type I diabetes
Type II diabetes
Malnutrition related type disease
Pregnancy related type diabetes
0a
single
null
Medicine
null
d25db791-7464-4861-bb3f-e94fe4a38286
Vomar-sphenoidal rostrum junction is?
Syndesmsis
Synostosis
Schindylesis
Gomphoiss
2c
single
C i.e. Schindylesis
Anatomy
null
fe754fa5-1cf8-4b83-8711-7f05f3b71948
Type II A is associated with all of the following, EXCEPT
Normal Anion Gap Acidosis
Hyper calciuria
Decreased urinary citrate
Minimum urinary pH < 5.5
2c
multi
Answer is C (Decreased Urinary citrate) Type II A is associated with normal or increased urinary citrate `Urine citrate levels are normal or high because of reduced proximal tubular reabsorption of citrate' -- Harrisons
Medicine
null
07dd2d6c-e766-4f55-949a-86ef5e732d2c
Comment on the diagnosis?
Down syndrome
Turner syndrome
Prader-Willi syndrome
Patau syndrome
0a
single
Ans. (a) Down syndrome.Notice the hypotonia with facial grimace and a wide gap between the first and second toe of the foot. The karyotype confirms it to be trisomy 21.Mnemonic for DOWN Syndrome is "CHILD HAS PROBLEM"* Cataracts/heart disease (Endocardial cushion defect)* Hypotonia/hyperthyroidism* Incur 5th finger/Inc...
Pathology
Cytogenetic Disorders
e3d8e380-cc66-4ff0-a6fa-6b01a3311d1f
Normal voice heard from 1 meter, intensity of sound reaching ear is
20 dB
40 dB
60 dB
80 dB
2c
single
Ans. is 'c' i.e. 60dB Intensity is the strength of sound which determines its loudness. It is usually measured in deeibeis (dB). o Following are intensities when a person is at a distance of one meter from sound source. Whisper 30dB Normal conversation 60dB Shout 90 dB Discomfo of ear 120dB Fain in ear 130 dB
Social & Preventive Medicine
null
4a001426-e606-4576-ac11-d63bb8a69d3b
Reilly bodies are inclusion bodies seen in hurler's disease within
Lymphocytes
Fibroblast
RBC
WBC
0a
single
null
Pathology
null
535459a7-2808-4acf-946b-a722c91bee44
Adipose tissue releases free fatty acids in the
Fasting state
Resting state
Active state
All of the above
0a
multi
null
Biochemistry
null
b4d5e71d-cd7b-40ba-9068-642397b81d7e
With reference to Escherichia coli infections, the following are true, EXCEPT:
Enteroaggregative E. coli is associated with Persistant diarrhoea
Enterohemorrhagic E. coli can cause haemolytic uraemic syndrome
Enteroinvasive E. coli produces a disease similar to salmonellosis
Enterotoxigenic E. coli is a common cause of travelers' diarrhoea
2c
multi
Enteroinvasive E. Coli shares many genetic and clinical features with Shigella not salmonella. Enterotoxins produced by it initially induce secretory small-bowel diarrhea. Subsequently it colonize and invades the colonic mucosa resulting in the development of inflammatory colitis characterized by fever, abdominal pain,...
Microbiology
null
60a31d43-1ec5-4ee3-aa53-2c6bcfb12a0d
Dissociative anaesthesia is produced by - (PGI 99)
Ketamine
Etomidate
Propofol
Thiopentone
0a
single
Ans. is 'a' i.e., Ketamine Dissociative anaesthesia is characterized by profound analgesia, immobility, amnesia with light sleep and feeling of dissociation from once own body and the surroundings Cataleptic state. Ketamine (phencyclidine) induces dissociative anaesthesia.
Anaesthesia
null
4f4c73a9-3f39-4020-83b2-fc6db24ff72d
Brunner's glands secrete an alkaline product that helps achieve optimal pH for the activity of pancreatic enzymes. Where are these glands located?
At the base of villi throughout the small intestine
In the epithelium of the ampulla of Vater
In the mucosa and submucosa of the jejunum
In the submucosa of the duodenum
3d
multi
Brunner's glands are located in the submucosa of the duodenum. These glands are connected to the intestinal lumen by ducts that open into ceain crypts. They secrete an alkaline product that protects the duodenal mucosa from the acidic chyme and helps achieve optimal pH for pancreatic enzymes. The small intestinal villi...
Anatomy
null
267b9636-2514-4f81-81b9-8c5e392872e5
Vertebra plana is seen in – a) Eosinophilic granulomab) Traumac) Paget's diseased) Malignancy
acd
abd
abc
ab
1b
single
null
Radiology
null
ca41edbf-ce4e-412b-9a1b-cfc46a715233
Layer of non-pigmented epithelium of the ciliary body is the forward continuation of the:
Pigment epithelium of the retina
Sensory retina
Internal limiting membrane of the retina
Bruch's membrane of the choroid
1b
single
Ans. Sensory retina
Ophthalmology
null
7b981ced-70b6-41ef-9d3c-b2531edc6b18
HIV is not seen in:
Tears
Cervical secretion
Semen
Blood
0a
single
Ans: a (Tears) Ref: Harrison, 16th ed, p. 1079; 17th ed, p. 1144HIV is not usually found in tears. It is usually transmitted by semen, cervical secretion and blood.HIVClinical features1. Primary infectionIt is symptomatic in 70-80% of cases and usually occurs 2-4 weeks after exposure. The major clinical manifestations ...
Medicine
Infection
75fd9c78-57d3-485f-a655-74275a373ce1
Which drug should be avoided in pregnancy ?
Phenytoin
Insulin
Heparin
All
0a
multi
null
Pharmacology
null
0510b688-3e56-4eb7-a4a4-e1503e0056f8
The shunt surgery to control variceal bleeding in noncirrhotic poal fibrosis is done, if:
Very low platelet count
Upper GI bleeding at the age of 30
If beta blockers contraindicated
Associated with cirrhosis
0a
single
Shunt surgery is preferred in Non cirrhotic poal fibrosis with: Symptomatic large splenomegaly Very low platelet count (<20,000) Stays far away from a good medical center where an upper GI bleed can be tackled Rare blood group Endoscopic variceal ligation is preferred as the treatment modality for UGI bleeding in NCPF....
Medicine
null
544e2fe4-6d5c-4e43-afbd-01e8089dfa7f
All are cndopeptidases except -
Trypsin
Chymotripsin
Carboxypeptidase
None
2c
multi
Ans. is 'c' i.e., Carboxypeptidase o Trypsin, chymotrypsin and elastase are endopeptidases, which means that they split peptide linkages in the middle of the amino acid chain, not at either end.o Carboxypeptidases (A and B), on the other hand, are exopeptidases, i.e., They split the peptide linkage at the carboxyl end ...
Biochemistry
Biological Function of Proteins
c6a75321-01aa-4196-ab85-287a3c19e41a
A 25-year-old lady presented with fever of one month duration, ataxia and headache. Brain imaging showed dilated ventricles with basal exudates. Which among the following is the most likely CSF finding?
Lymphocytosis, low glucose, low protein
Lymphocytosis, normal glucose, high protein
Lymphocytosis, low glucose, high protein
Polymorphonuclear pleocytosis, normal glucose, high protein
2c
single
Ans. c. Lymphocytosis, low glucose, high protein (Ref: Harrison 19/e p1111, 18/e p3414)Presence of significant basal exudates, together with dilated ventricles (hydrocephalus) in a young female with prolonged history of fever and headache suggests a diagnosis of tubercular meningitis. Tubercular meningitis is character...
Medicine
C.N.S.
224b7671-2fca-4aab-88ff-84dc70995175
Agammaglobulinemia can present with?
Rhinitis
Bronchiectasis
Giardia infections
All above
3d
multi
ANSWER: (D) All aboveREF: Harrisons 18th ed chapter 361Major signs and symptoms of B cell defects are due to inadequate production of antibodies, and most mucosal membranes are left unguarded, hence leading to their infections.Defective antibody production allows the establishment of invasive, pyogenic bacterial infect...
ENT
Rhinitis
259f1d61-b0ab-4b85-9c22-bfdab4a154ee
Most commonly used scalpel blade for intraoral surgery is:
No.15
No.11
No.12
No.10
0a
single
Most commonly used scalpel blade for intraoral surgery – No. 15 The blade used primarily for making small stab incisions, such as for incising an abscess – No. 11 Blade commonly used for skin incisions – No. 10 blade The hooked blade commonly used for mucogingival procedures – No. 12 blade The blades commonly used in g...
Surgery
null
2e2a5531-d834-4eeb-8e9d-e23be2160c86
Nef gene in HIV is for use-
Enhancing the expression of genes
Enhancing viral replication
Decreasing viral replication
Maturation
2c
single
nef ( negative factor gene) down regulates viral replication. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-572
Microbiology
Virology
ca1b5d9e-cc88-4426-a54c-df4cd5ece4ed
The use of tamoxifen for breast cancer can cause all of the following adverse effects, except:
The use of tamoxifen for breast cancer can cause all of the following adverse effects, except:
Endometrial carcinoma
Carcinoma in contralateral breast
Cataract
2c
multi
Tamoxifen reduces the recurrence rate of breast cancer in ipsilateral as well as contralateral breasts. Adverse effects associated with the use of tamoxifen are: 2-3 fold increased risk of thromboembolism 2-3 fold increased risk of endometrial carcinoma Hot flushes, vomiting, vaginal discharge, menstrual irregularities...
Pharmacology
null
71c96822-24ad-4ebe-b559-6614bce7b420
Extragonadal germ cell tumors occur in all of the following except -
Sacrococcygeal region
Mediastinum
Brain
Testis
3d
multi
Extragonadal germ cell tumors occur at : - Mediastinum → M.C. site.       Retroperitoneum  → 2nd M.C. site.      Sacrococcygeal region → Sacrococcygeal teratoma. Pineal gland
Pathology
null
9f76fa19-1be4-4a9f-be6c-b0ed88c559e3
Which among the following is the commonest type of parotid tumor?
Pleomorphic tumor
Wahin's tumor
Adenoid cystic Ca
Secondaries
0a
single
Pleomorphic adenomas, or benign mixed tumors, are the most common neoplasms of the salivary glands. They represent approximately 60-70% of all parotid tumors and 90% of submandibular benign tumors. These neoplasms affect females more than males and are commonly seen in the third to sixth decades of life. It presents as...
Surgery
null
1c875c19-6eef-47ac-8620-8b7800064b86
Barrel shaped spores (arthospores) is seen with -
Blastomyces
Histoplasma
Coccidioides
Candida
2c
single
null
Microbiology
null
d5605c29-6b07-4d43-8b2f-0047f03cf82a
Which of the following enters the TCA cycle at succinyl - CoA?
Tyrosine
Methionine
Tryptophan
Histidine
1b
single
Valine Isoleucine Methionine conves to Propionyl CoA & then conves to Succinyl CoA & enters the cycle.Ref: DM Vasudevan Textbook of Medical Biochemistry, 6th edition, page no: 221
Biochemistry
Respiratory chain
3f57a851-22b3-434f-b713-67933712d829
Nasion lies at the junction of
Frontonasal and internasal suture
Frontonasal and interparietal suture
Frontonasal and frontozygomatic suture
Frontogomatic and internasal suture
0a
single
The nasion is the point where the internasal and frontonasal sutures meet. It lies a little above the floor of the depression at the root of the nose, below the glabella. Nasion is termed as the central point of the frontonasal suture. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.
Anatomy
Head and neck
457497c5-ef40-4026-9511-7894bb1362f3
Women with Plummer Vinson develops which cancer ?
Pyriform fossa
Esophagus
Subglottis
Epiglottis
1b
single
null
Surgery
null
6cb7d65c-ea7d-4e07-be18-c4d17caf5af1
Cementogenesis begins after how many days of root end resection:
6 days.
10-12 days.
28 days.
8 weeks.
1b
single
null
Dental
null
6ac71b15-eb6c-4edd-9138-a1fad3ba9dcd
Vitamin deficiency causing optic atrophy -
Vitamin A
Vitamin B
Vitamin C
Vitamin D
1b
single
Ans. is 'b' i.e. Vitamin B Nutritional optic atrophyo The exact mechanism by which nutritional deficits damage the optic nerve has not been elucidated. Although the etiology is likely multifactorial, most clinicians agree that in patients who abuse ethanol and tobacco, malnourish- ment is often present and undemutritio...
Ophthalmology
Diseases of the Optic Nerve
cd7608a5-aabd-4670-84d4-7438044610a0
Which of the following instructions is not given if a second puff is required from this device?
Wash mouth between two puffs
Wait for one minute before taking the second puff
Shake again
Keep mouth piece dry
0a
single
Ans. A. Wash mouth between two puffsRecommendations for correct inhaler technique: -a. Remove capb. Check does counter (if applicable)c. Hold inhaler upright and shake welld. Breathe out gently, away from the inhalere. Put mouthpiece between teeth without biting and close lips to form good sealf. Start to breathe in sl...
Pharmacology
Miscellaneous (Pharmacology)
9eb17295-7776-45a3-aa9a-55c6c61595c5
A 45-year-old woman underwent a modified radical mastectomy 4 years ago. She was treated for multiple bone metastases with cyclophosphamide, doxorubicin, and fluorouracil for 6 months. She is complaining of exeion on exercise, swelling of the legs, and swelling around eyes in the morning. On examination, she has bilate...
Systolic dysfunction CHF
Drug induced cardiac toxicity
Metastatic cardiac disease
Pneumonia
1b
multi
Answer is B (Drug induced cardiac toxicity) Features of cardiac failure in a patient on doxorubicin suggests the possibility of Anthracycline induced cardiac toxity.Risk of Anthracyclinc induced cardiac toxicity is increased with concomitent radiation and cyclophosphamide. cardiac failure after 6 months of chemotherapy...
Medicine
null
e88494a8-87d4-4992-9e62-e60abbac2e42
The structure marked with arrow is most likely:
Pulp obliteration
Reactionary dentin
Calculus
Plaque
2c
single
Because of its relatively low radiodensity, calculus is better visualized on images made with reduced exposure.
Radiology
null
5cb47606-0054-493f-8f14-18f172907a09
The histology of Lobular carcinoma of breast reveals-
Single file pattern
Pleomorphic cells in sheets
Clustersl/lslands of cells with mucous lakes
Solid syncytium like sheets
0a
single
Invasive lobular carcinoma consists of cells morphologically identical to the cells of LCIS. Two thirds of the cases are associated with adjacent LCIS. The cells invade individually into stroma and are often aligned in "single-file" strands or chains. This growth pattern correlates with the presence of mutations that a...
Pathology
Breast
7896c431-eead-4bf0-b3c9-ddcd7a263239
You are in the eye OPD and wish to use a topical beta blocker in a patient. The chosen drug by you should have all the following properties EXCEPT:
Strong local anaesthetic activity
High lipophilicity
High ocular capture
Low systemic activity
0a
multi
Drugs having local anesthetic property will increase the risk of corneal ulcers.
Pharmacology
null
f6f3d5d5-3bd6-417f-bd19-7071d6056658
Medical treatment of pancreatitis includes :
Cholestyramine
Aprotinin
Calcium
Glucagon
2c
single
Answer is C (Calcium) :
Medicine
null
a1d60a6a-0e17-46d7-8f00-8a3ec21e6c8b
Alkalinization of urine is required for decreasing poisoning due to
Barbiturates
Amphitamines
Alcohol
Morphine
0a
single
For acidic drug poisoning like (barbiturates, salicylates and methotrexates) ,urinary alkinization agents are prescribed where as basic drug poisoning (morphine, amphetamine ,atropine etc) urinary acidification agents are prescribed. Refer Ltd 7/e p29
Anatomy
General anatomy
1d5b1388-594a-4eaa-a321-3419d16ae37d
Eastern equine encephalitis virus is associated with a high fatality rate. Control of the disease could be possible by eradication of
Horses
Birds
Mosquitoes
Fleas
2c
single
Eastern equine encephalitis (EEE) is a severe disease usually seen in the summer months when Aedes mosquitoes are prevalent. In 1996 and 1997, there were several outbreaks in the Northeast United States. Control of EEE is a function of mosquito eradication. Horses and humans are accidental hosts. While draining of swam...
Microbiology
Virology
5f3e04e0-604c-4e70-b34d-de41f7ae1382
Most common cause of Mediastinitis is:
Tracheal rupture
Esophageal rupture
Drugs
Idiopathic
1b
single
Answer is B (Esophageal rupture): Most cases of acute mediastinitis are due to esophageal perforation or occur after median sternotomy for cardiac surgery- Harrison Acute Mediastinitis Chronic Mediastinitis 1. 2. Esophageal rupture Q Median sternotomy for cardiac surgery 1. 2. 3. Tuberculosis / Histoplasmosis (most cas...
Medicine
null
c07bfc2e-6a14-4078-be31-d59e7803f4db
All are true about pre eclampsia except
Cerebral hemorrhage
Necrosis of liver
Glomerular endotheliosis
DVT
3d
multi
Pathophysiology of preeclampsia: In Brain: The main finding is cerebral vasospasm.Small cerebral haemorrhages,thrombosis, and fibrinoid necrosis can occur especially in eclampsia.Cerebral oedema also usual in eclampsia In Liver: Peripoal thrombosis and fibrin deposition,hemorhages,necrosis are seen in the liver.There i...
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
bddb63cc-d1b9-45f5-be1f-f183984961bb
All are true regarding nitrous oxide except
Nitrous oxide is good analgesic agent.
Nitrous oxide cylinder is blue coloured
Inhibits thymidylate synthetase enzyme
Good agent to use in pan retinal photocoagulation
3d
multi
Nitrous oxide being combustible agent, is contraindicated in laser surgeries.
Anaesthesia
null
2439f79f-4894-47ea-9dda-e3abd7f2d343
All of the following may be seen with Neuroleptic malignant syndrome except -
Hypothermia
Altered consciousness
Muscle rigidity
Involuntary movements
0a
multi
Ans. is 'a' i.e., Hypothermia Features of Neuroleptic malignant syndrome o Marked muscle rigidity o Semiunconciousness o High fever (not hypotermia) o Extrapyramidal effects (involuntary movement) o Autonomic instability (Fluctuating BP & Hea rate) o Increased CPK.
Pharmacology
null
f68501ac-4870-4a18-9606-620be2bd119e
Which of the following is reducing sugar
Sucrose
Isomaltose
Trehalose
All of the above
1b
multi
Sucrose and Trehalose are non reducing sugars. Isomaltose is a disaccharide similar to maltose but with α (1,6) linkage instead of α (1,4) linkage.
Biochemistry
null
fc2e7fd7-84a6-4d17-868f-c9496d4ad359
Which of the following is not a cachetic gene?
APEH
MC4R
Smad7
Smad3
2c
single
Ans is 'c' i.e. Smad 7 o Smad 7 gene delivery prevents cachexia.o Smad-3y melanocortin - 4 receptor (MC4R) and APEH (acylpeptide hydrolase) genes have been implicated in causation of cancer cachexia.
Pathology
Nature of Gene Abnormalities