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135
05e5898b-913b-4467-b675-eb38361aa44f
Mirena (LNG IUCD) has to be replaced after :
1 year
5 years
3 years
6 months
1b
single
Mirena (LNG IUD) contains a total of 52 mg levonorgestrel (LNG) LNG is released into the uterine cavity at a rate of approximately 20 microgram/day. Act mainly by local progestogenic effects Effective for up to 5 years.
Gynaecology & Obstetrics
Contraceptives
7607f012-08fa-4e68-aa2d-ae1f39265044
5 year old Boy with something coming out of the anus with pedicle attached to rectal/ anal wall and bright red bleeding- most common diagnosis -
Juvenile rectal Polyp
Pedicle pile
Fissure
CA Colon
0a
multi
Ans. is 'a' i.e., Juvenile rectal Polyp * Juvenile polyps are the most common type of childhood polyp, occurring in up to 1% of preschool children. They are usually solitary polyps found in the rectum which most commonly present with rectal bleeding.* These are hamartomatous polyps, which are usually pedunculated but c...
Surgery
Rectum
cda4f0a7-be59-4780-827f-bbf7afc10f67
Glutathione requires which vitamin to act as antioxidant -
Vitamin E
Niacin
Vitamin C
Vitamin A
1b
single
Ans. is 'b' i.e., Niacin o Option a, c & d are themselves antioxidants, but glutatbion requires niacin as NADPH.o NADPH is necessary tor the maintenance of a reducing environment in the cell.o NADPH plays a key role in antioxidant defences by converting the oxidized glutathione into the reduced glutathione, which is pr...
Biochemistry
Vitamins
a14eb7f8-a687-4b51-a34f-3b73bf069f80
Prophylactic Chemotherapy is indicated after evacuation of H.Mole in all, Except:
Initial level of urine HCG is 40000 IU after 6 week of evacuation
Increase in HCG titre 24000 IU after 10 week of evacuation
Metastasis
Nulliparous lady
3d
multi
null
Gynaecology & Obstetrics
null
fe31d6fe-2adc-4e45-a333-3be436b147ef
Oral contraceptive pills decrease incidence of all of the following conditions except :
Salpingitis
Hepatic adenoma
Ovary CA
Fibroadenosis
1b
multi
Hepatic adenoma
Gynaecology & Obstetrics
null
9c98da14-e30e-4e31-834a-0c5345322779
A 14 year old boy with difficulty in walking and behavioural disturbance, recovered from prolonged jaundice recently, has bluish pigmentation over lunula. The next investigation to be done:
Nail fold cappillaroscopy
Slit lamp examination
Biopsy of the pigmented area
Ankle-brachial pressure index
1b
single
Neurological involvement + Jaundice + Azure Nails (Bluish discoloration of nails) = Wilson's disease Dx: Slit lamp examination and 24 hrs urinary copper Rx: for Neurological feature - Tetrathiomolybdate
Medicine
JIPMER 2018
289eae66-41e6-4a0a-919a-43dee10bd8da
Intra-aerial calcium gluconate infusion is used in the management of burns caused by
Nitric acid
Hydrofluoric acid
Formic acid
Hydrochloric acid
1b
single
Hydrofluoric acid causes Hypocalcemia. Calcium based therapies are main stay of treating Hydrofluoric acid burns. Topical application of calcium gluconate onto wounds and IV administration of calcium gluconate for systemic symptoms. Intra-aerial calcium gluconate infusion provides effective treatment of progressive tis...
Surgery
Burns
4f359529-2be5-46cb-b51d-cca080fa0094
A 2-year-old female child was brought to a PHC with a history of cough and fever for 4 days with inability to drink for last 12 hours. On examination, the child was having weight of 5 kg, and respiratory rate of 45/minute with fever. The child will be classified as suffering from:
Very severe disease
Severe Pneumonia
Pneumonia
No Pneumonia
0a
single
The child is unable to drink water for 12hrs & weight of the child is 5kg which is less than expected (12kg), which shows severe malnutrition. Inability to drink constitutes a danger sign amongst the clinical manifestations and classifies the pneumonia as very severe disease. Ref: Park's Textbook Of Preventive And Soci...
Social & Preventive Medicine
null
fcda0aec-748c-4dd9-869a-ae11e12e274a
Familial amylodotic polyneuropathy is due to amyloidosis of nerves caused by deposition of
Amyloid associated protein
Mutant calcitonin
Mutant transthyretin
Normal transthyretin
2c
single
Ref Robbins 9/e p259 Familial (Hereditary) Amyloidosis A variety of familial forms of amyloidosis have been described; most are rare and occur in limited geographic areas. The best-characterized is an autosomal recessive condition called familial Mediterranean fever. This is a febrile disorder characterized by attacks ...
Anatomy
General anatomy
a7def227-b2cc-4dfa-8540-b1ef4b815d89
Which of the following is not a presumptive sign of pregnancy -
Jacquemier's sign
Dalrymple sign
Hegar's sign
Palmer's sign
1b
single
Ans. is 'b' i.e., Dalrymple's sign o The following are presumptive signs for diagnosis of pregnancy:# Breast changes: Enlargement with vascular changes with delicate veins visible under the skin.# Jacquemier's sign/Chadwick's sign: Dusky hue of the vestibule and anterior vaginal wall, due to local congestion.# Osiander...
Gynaecology & Obstetrics
Diagnosis of Pregnancy
47c9a687-ff04-4281-a989-9d3dad166aa7
False about Hyperophic gastropathy is
Seen in menetriers disease and ZES
It is associated with malignancy
It shows cerebriform rugacity on stomach
Produce MALTomas
3d
multi
It is seen in menetriers disease&ZES &it associated with malignancies & it form cribriform rugacitu on stomach. The condition needs to be differentiated from other forms of hyperophic gastropathy such as Zollinger-Ellison syndrome, hyperophic hypersecretory gastropathy, lymphocytic gastritis, or gastric carcinoma MALTo...
Pathology
G.I.T
72876b0b-9d20-442a-8c02-924c06267331
Body temperature regulation centre is located at
Pituitary
Thalamus
Hypothalamus
Basal ganglia
2c
single
Anterior hypothalamus, responds to heat;Posterior hypothalamus, responds to cold. Ref: Ganongs Review of medical physiology;25 th edition ; pg :309; table 17-1.
Physiology
Nervous system
c45a427e-5177-43f5-942c-aad93322cc71
High Air velocity is measured by -
Psychrometer
Anemometer
Kata thermometer
Hygrameter
1b
single
Ans. is 'b' i.e.. Anemometer
Unknown
null
2b38e0a4-77af-4c6e-a9fe-d1299766a86f
A destitute woman is admitted to the hospital with altered sensorium and dehydration; urine analysis shows mild proteinuria and no sugar; what other test would be desirable:
Fouchet
Rothera
Hays
Benedicts
1b
single
Women in the question stem with altered sensorium and dehydration is suffering from ketoacidosis. Absence of sugar exclude the diagnosis of diabetic ketoacidosis. So ketosis could be due to starvation which can be detected by Rotheras test. During starvation acetylCoA takes alternate fate to form ketone bodies. Ref: Te...
Biochemistry
null
97ea27b5-607d-4d97-a177-32de8a4c97b3
A sixteen year old boy receives a superficial cut on the thumb side of his forearm. The superficial vein most likely affected is the?
Basilic
Cephalic
Median antebrachial
Median cubital
1b
single
There are two large cutaneous veins running up the arm. Both veins take origin from the dorsal venous arch of the hand and run up the lateral and medial sides of the arm. On the medial side (near the 5th digit) there is the basilic vein. On the lateral side (by the thumb), there is the cephalic vein. Since the infectio...
Anatomy
null
aa4c0eb6-c59d-4a8a-bdad-68c10fa7f5d7
Defect in Snurps causes-
Sickle cell anemia
Thalassemia
Marfan syndrome
EDS
1b
single
Ans. is 'b' i.e., Thalassemiao Defective splicing (defect in snurps) is the most common mutation causing thalassemia,o Molecular defect in pathogens is of thalassemia:-b-Thalassemiao Most common type of genetic abnormality in b-thalassemia is point mutation i.e., nonsense.o Some may also occur due to deletion or insert...
Biochemistry
Molecular Genetics
b1e3103d-1c71-4128-ba1a-343872829045
Not true about Red degeneration of myomas is-
It occurs commonly during pregnancy
Immediate surgical intervention is needed
Due to interference with blood supply
Treated with analgesics
1b
multi
Ans. is 'b' ie immediate surgical intervention needed Red degenerationis the most frequent* complication of myomas during pregnancy.The tumour assumes a peculiar purple red colour.It usually occurs due to thrombosis of large veins in the tumour.it has a peculiar fishy odour*Clinical featuresAcute onset of pain over the...
Gynaecology & Obstetrics
Clinical Features, Diagnosis, and Pathology
a389ceb0-41d1-4e75-a421-1f492e56d15c
Which of the following is not supplied by C8 T1 -
Abductor pollicis brevis
Extensor indicis
Palmar interossei
3rd & 4th lumbricals
1b
single
Small muscles of hand include- Thenar, Hypothenar, interossei and lumbricals. They are supplied by C8-T1. Extensor indicis is supplied by C7, C8
Anatomy
null
904fa341-d6ec-4cb5-a74c-845e90bcb418
All the following enzymes activity is increased in fasting state except
Acetyl CoA carboxylase
Carnitine acyl transferase
Phospho enol pyruvate carboxykinase
Pyruvate carboxylase
0a
multi
MetabolismRegulatory enzymesLipid metabolism Fatty acid oxidation Carnitine acyltransferase 1KetogenesisHMG CoA synthaseLipolysis Hormone-sensitive lipaseCarbohydrate metabolism Glycogenolysis Glycogen phosphorylase Gluconeogenesis Pyruvate carboxylase Phosphoenol pyruvate carboxykinase (PEPCK)Fructose1,6 bisphosphatas...
Anatomy
All India exam
bdd3f6c7-4e03-4edf-b158-3b8b7f01920e
Anaesthetic agent not metabolized by body is?
N20
Gallamine
Sevofluorane
Halothane
0a
multi
Ans. (a) N20Ref: Miller's 7thedch: 24
Anaesthesia
Miscellaneous General Anesthesia
09f5cee7-26df-478f-b337-5df30b92dd4a
Which of the following is not true about hydroquinone?
It is a weak hypopigmenting agent
It inhibits tyrosinase
Response is incomplete and pigmentation may recur
It should not be used for melasma or chloasma of pregnancy
3d
multi
Ans. is'd'i.e., It should not be used for melasma or chloasma of pregnancy .Ref: KDT Vhle p. 8921Hydroquinone:It is a weak hypopigmentation agent.Inhibits tyrosinase and other melanin forming enzymes, decreases formation of and increases degradation of melanosomes.Regular application (as 2-6% lotion or cream) for month...
Pharmacology
null
c16fd188-cfff-49ff-803c-71552b1dadcf
A pelvis characterized by an anteroposterior diameter of the inlet greater than the transverse diameter is classified as:
Gynecoid
Android
Anthropoid
Platypelloid
2c
single
Ans. C. AnthropoidBy tradition, pelvis are classified as belonging to one of four major groups. The gynecoid pelvis is the classic female pelvis with a posterior sagittal diameter of the inlet only slightly shorter than the anterior sagittal diameter. In the android pelvis, the posterior sagittal diameter at the inlet ...
Gynaecology & Obstetrics
Fetal Skull and Maternal Pelvis
83c2fe09-251a-4ff2-bf62-1a95eda44f9d
Celiac plexus block all the following is true except ?
Relieved pain from gastric malignancy
Cause hypotention
Can be used to provide anesthesia for intra abdominal surgery
Can be given only by retrocrural (classic) approach
3d
multi
Ans. is 'd' i.e., Can be given only by retrocrural (classic) approach Celiac plexus block can be done by following three approaches : Retrocrural (classic) approach, anterocrural approach and splanchnic nerve block. See explanation- 4 of session- 8 of Anaesthesia of All India 2014-15 pattern of this book.
Anaesthesia
null
8231d930-2b97-4d83-88f2-683624577213
Which of the following is used in mixed dentition classification of malocclusion
Angles classification
Simon's orbital plane
Flush terminal plane
All of the above
2c
multi
null
Dental
null
190baefd-ef1d-4fb0-99ef-83a2d877d2b1
All of the following are the disadvantages of anesthetic ether, except
Induction is slow
Irritant nature of ether increases salivary and bronchial secretions
Cautery cannot be used
Affects blood pressure and is liable to produce arrhythmias
3d
multi
Ether has high blood solubility (high blood : gas partition coefficient) → induction is slow. It is irritant in nature and increases salivary & respiratory secretions. Blood pressure is maintained because of reflex stimulation and high sympathetic tone. It does not sensitizes the heart to arrhythmogenic action of adren...
Anaesthesia
null
4e434e4e-0592-4760-80f6-4e6a60bee821
Minimum fluid collection required for radiological detection of pleural effusion in lateral decubitus view is: September 2009
15 ml
25 ml
35 ml
45 ml
1b
single
Ans. Amount of pleural fluid required to cause a blunted costophrenic angle discernible on chest radiography is more than 300 ml. A chest computerized tomography scan is more sensitive than a simple chest x-ray and is often used for assessment of loculated effusions because, in some instances, up to 500 cc of loculated...
Radiology
null
c0245f0d-2ee9-428f-871d-afc265ae792d
Pseudopolyps are features of –
Crohn's disease
Ulcerative colitis
Celiac sprue
Whipple's disease
1b
single
Ulcerative colitis Ulcerative colitis is an inflammatory bowel disease characterized by - Inflammation involving only the mucosa and submucosa Formation of pseudopolyps Involvement is in a continuous fashion (absent of skip lesions which are characteristic of CD) Ulcerative colitis involves the rectum and extends ...
Pediatrics
null
fdf560f4-2e94-4de6-8641-21ec078b6287
Coracoid process of the scapula is:
Pressure epiphysis
Traction epiphysis
Atavistic epiphysis
Aberrant epiphysis
2c
single
Ans. C Atavistic epiphysisRef: Clinical Anatomy, Kulkarni 2nd ed. P 73TYPES OF EPIPHYSIS* Pressure: Seen at the end of long bones subjected to pressure. E.g. Femur, head of humerus, condyles of tibia and femur.* Traction: Formed due to pull of muscles. E.g. Mastoid process, tibial tuberosity, tubercles, trochanters.* A...
Anatomy
Joints
1597f5a5-8d89-4bca-91f3-332ab3c0d0c1
Which of the following is the least likely cause of infant moality rate?
Severe infections
Prematurity
Tetanus
Bih asphyxia
2c
single
The principal causes of infant moality in India are low bih weight (57%), respiratory infections (17%), diarrhoeal diseases(4%), congenital malformations (5%), cord infections (2%), bih injury (3%) Park 23e pg:569
Social & Preventive Medicine
Maternal and child care
50ac2d36-f2d5-414d-8ac8-639beccbd8c7
Mittelschimerz pain is -
Pain during onset of menstrual cycle
Pain during the usual time of ovulation in menstrual cycle
Pain during the or at the end of menstrual cycle
Pain during menstrual bleeding
1b
single
Ans. is 'b' i.e., Pain during the usual time of ovulation in menstrual cycle o Has been explained in previous sessions.
Gynaecology & Obstetrics
Normal Menstrual Cycle
64258a36-8a3f-4b35-af99-dc8dbc7ab71d
Osteoporosis is seen in all the following except-
Thyrotoxicosis
Rheumatoid ahritis
Hypoparathyroidism
Steroid therapy
2c
multi
Osteoporosis It refers to reduction ofbone mass per unit volume (loss of matrix and defective mineralisation) (Fig. 9.47). Aetiology 1.Involutional 2.Endocrinological 3.Gastrointestinal 4.Haematological 5.Rheumatological 6.Collagen vascular Normal bone Type I (postmenopausal) and Type II (senile) Hypehyroidism Hyperpar...
Medicine
Endocrinology
bb09ecaf-276b-43f1-bc34-38e5bc784394
All are true about rifampicin except :
Microsomal enzyme inducer
Used in treatment of meningiococcal meningitis
May cause OCP failure
Bactericidal in nature
1b
multi
null
Pharmacology
null
4df3470a-67b3-4deb-8794-7e42b88b79e6
All local anesthetic produces vasodilation on local application except
Cocaine
Lignocaine
Bupivacaine
Ropivacaine
0a
multi
Cocaine is a vasoconstrictor as it is sympathomimetic. * Cocaine was the first local Anesthetic to be used clinically. IT is only natural local anesthetic. Koller introduced this in the field of ophthalmology. It is the only local anesthetic with vasoconstrictor action. It is sympathomimetic and inhibits metabolism of ...
Anaesthesia
Regional Anesthesia
97378996-aa73-4ec6-9dad-3d4b279355cb
Which is not elevated in a child presenting with icterus, Pruritus and clay coloured stools
Gamma glutamyl transpeptidase
Alkaline phosphatase
5'- nucleotidase
Glutamate dehydrogenase
3d
single
The child is suffering from obstructive jaundice or Cholestasis Enzymes elevated in Chloestasis ALP 5'-Nucleotidase Gamma glutamyl transpeptidase Ref: Harrison's 19th edition Pg no : 1997
Anatomy
G.I.T
b1821909-04aa-46c2-a699-e8d3fabd174f
Distal muscles of the hand needed for fine wrok are controlled by-
Radial nerve
Median nerve
Ulnar nerve
Axillary nerve
2c
single
Ans. is 'c' i.e., Ulnar nerve * Ulnar nerve is also known as musicians nerve as it is needed to carry out fine and precision movements of the hand.
Anatomy
Upper Extremity
e1873706-67c8-4986-b99b-0a7ab5b73a88
In humans and other primates, as well as in guinea pigs, this vitamin cannot be synthesized, because of the absence of the enzyme L-gulonolactone oxidase; the vitamin is:
Pantothenic acid
Nicotinic acid
Ascorbic acid
Folic acid
2c
single
null
Biochemistry
null
8b07b490-afbd-4e03-9556-ebd2ab7a0e79
Psoriasis is associated with:
Geographic tongue
Benign median rhomboid glossitis
Lupus erythematosus
Lupus vulgaris
0a
single
null
Pathology
null
71d0996a-5067-465d-8a58-b373d5949e55
Diagnostic feature of parathyroid carcinoma is
Cytology
Metastasis
Clinical features
All
1b
multi
Parathyroid carcinomas may be circumscribed lesions that are difficult to distinguish from adenomas. Cells are usually uniform and resemble normal parathyroid cells and of enclosed in a capsule. Diagnosis of carcinoma based on cytologic detail is unreliable , and invasion of surrounding tissues and metastasis are the o...
Pathology
Endocrinology
0eac0c29-270f-4d85-a61c-6eec02bd1b01
D.I.C. is seen in-
Acute promyelocytic leukemia
Acute myelomonocytic leukemia
CMC
Autoimmune hemolytic anemia
0a
single
Answwr is option 1 Abstract Malignancy is associated with a "hypercoagulable" state and a high risk for thrombohemorrhagic complications. Clinical complications may range from localized thrombosis to bleeding of varying degrees of severity because of disseminated intravascular coagulation (DIC). Life-threatening bleedi...
Pathology
Haematology
135aa164-35c1-4bcd-ac54-69e8a7c5f2e0
Halting a disease at its incipient stages and preventing its complications is known as:
Primordial prevention
Primary prevention
Secondary prevention
Tertiary prevention
2c
single
null
Dental
null
1193b6fc-152a-4d21-a695-ecb00edcb1d1
The most common ocular motility defect noted in ocular Graves' disease is due to involvement of:
Inferior rectus
Medial rectus
Medial rectus
Inferior oblique
0a
single
Ans. Inferior rectus
Ophthalmology
null
d8fc3ba8-3ac0-4052-8cd5-1acf7331b66c
Foreign body aspirated during dental procedures can be retrieved by:
Bronchoscopy
Gastroscopy
Arthroscopy
None of the above
0a
multi
null
Medicine
null
c91799d3-9837-4a4c-8e4d-e2b2976d8e7f
Drug of choice for neurogenic diabetes insipidus
Vasopressin
Terlipressin
Desmopressin
Pralipressin
2c
single
Desmopressin is used to treat neurogenic diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease it acts as an agonist to vasopressin receptor or ADH receptor- produce antidiuresis- less urine production-used in DI, bedwetting, vasoconstriction - used in esophageal varices and produces vwf- used in von Wil...
Pharmacology
Kidney
98f7241b-16ba-4011-acd6-728a15ebbf47
A 20 Yr old male presented with repeated episodes of hemetemesis. There is no history of jaundice or liver decompensation. On examination the significant findings include splenomegaly (8cms below costal margin), and presence of esophageal varices. There is no ascites or peptic ulceration. The liver function tests are n...
Extra hepatic poal venous obstruction
Non-cirrhotic poal fibrosis
Cirrhosis
Hepatic venous outflow tract obstruction
1b
single
Non cirrhotic poal fibrosis Condition of liver characterized by widespread fibrosis of liver(mainly poal, subcapsular and rarely perisinusoidal) causing wide variation in normal architecture There is no true cirrhosis Etiology Chronic ingestion of arsenic, copper, vinyl chloride Clinical features Youny age patient with...
Anatomy
G.I.T
9c065672-3ab4-49c1-aaf5-b58b7aa7e7a7
Which electrolyte should be replenished in hyperophic pyloric stenosis ?
Sodium
Hydrogen
Chloride
Bicarbonate
2c
single
Hypochloremic, hypokalemic metabolic alkalosis is the classic electrolyte and acid-base imbalance of pyloric stenosis. This prolonged vomiting causes progressive loss of fluids rich in hydrochloric acid, which causes the kidneys to retain hydrogen ions in or of potassium. Reference: GHAI Essential pediatrics, 8th editi...
Pediatrics
Gastrointestinal tract
0802402b-33d8-4919-bad1-9bf38f293aa0
Feed forward mechanism is employmed in regulation of:
Temperature
Ph
Blood pressure
Blood volume
0a
single
Feed forward control ,in which no stimulus is required but the system still anticipates and makes changes.it is also known as anticipatory control or adaptive control .It is seen in: Temperature regulation Cephalic phase of gastric acid secretion Role of cerebellum in motor coordination Thinking about exercise Ref:Guyt...
Physiology
Endocrinology
72ae543f-1a8f-49d8-9603-6fbb8ca0912c
Not safe disposal but good for soil building:
Incineration
Controlled tipping
Composting
Dumping
2c
single
null
Dental
null
455c7574-68dc-4043-8a04-690c82222978
Perifascicular atrophy is seen in –
Duchenne muscular atroply
Wilson disease
Beckers's dystrophy
Dermatomyositis
3d
single
Muscle biopsy in dermatomyositis shows myonecrosis, myophagocytosis and perifascicular atrophy.
Pediatrics
null
bd1aace3-1eee-4dfd-a228-88f942cb4a0b
Antenatal screening is done using the following except :
Cord blood
Amniotic fluid
Chorionic villi
Peripheral lymphocytes
3d
multi
Peripheral lymphocytes
Gynaecology & Obstetrics
null
92e99552-7cad-4d3b-9934-caec27ac4c20
The intra-abdominal pressure during laparoscopy should be set between:-
5-8 mm of Hg
10-15 mm of Hg
20-25 mm of Hg
30-35 mm of Hg
1b
single
Laparoscopy Needle used for pneumoperitoneum veress needle Most commonly used gas: CO2 Flow of gas: 1L /min Intra-abdominal pressure: 12-15 mm Hg Trocar is inseed at or just below the umbilicus penetrating skin, superficial & deep fascia, fascia transversals & parietal peritoneum
Surgery
Robotics, Laparoscopy and Bariatric Surgery
aeb39b20-8826-4751-aa17-aac74cbcd000
Cells which surround the oocyte in Graafian follicle are called:
Discus proligerus
Cumulus oophorus
Luteal cells
Villus cells
1b
multi
Oocyte lies eccentrically in the ovarian (Graafian) follicle surrounded by some granulosa cells called cumulus oophorus. Discus proligerus is the attachment point of the cumulus oophorus to the most peripheral granulosa cells of an antral follicle. Large fluid-filled antrum (A) Cumulus oophorus (CO) Membrane granulose ...
Anatomy
Development period- week 1,2,3,4
0a1cf974-569c-4286-881a-55592fcf4a33
In transtentorial herniation, a pa of the brain is displaced from the supratentorial to the infratentorial compament through the tentorial opening. It results in all of the following, EXCEPT:
Cheyne stokes respiration
Decerebration
Ipsilateral hemiparesis
Ipsilateral oculomotor paresis
2c
multi
The uncus (on the medial aspect of the temporal lobe) herniates under the tentorium cerebelli. The uncus can compress the oculomotor nerve (CN III), compromising the parasympathetic fibers and resulting in ipsilateral pupillary dilation with associated ophthalmoplegia ("down and out"). Cheyne-Stokes respirations are co...
Physiology
null
e708cb26-9264-44da-af61-ec3687b11492
Infection occuring after man's bite is -
Spirochetes
Staphylococcus
Anaerobic streptococci
Candida
1b
single
null
Microbiology
null
db10288b-db85-4bb6-9543-8fcaffec2dcf
Drug of choice in thyrotoxicosis in pregnancy is :
Carbimazole
Lugol's iodine
Propranolol
Radioactive iodine
0a
single
Carbimazole
Gynaecology & Obstetrics
null
8d991bef-7a5f-484c-9607-b47f4c55eeea
Which of the following is the skeletal muscle relaxant of choice in liver and renal disease ?
Mivacurium
Atracurium
Gallium
Vecuronium
1b
multi
Atracurium is degraded by both pH and temperature dependent Hofmann elimination (autolysis) and by ester hydrolysis; it therefore does not require a dosage adjustment in patients with renal or hepatic failure. However, acidosis and severe hypothermia decrease the rate of drug metabolism and should prompt dose reduction...
Anaesthesia
null
f6f557cd-5057-4830-8106-545556263b9a
Residual bodies are
Mitochondria
Nucleus
Golgi apparatus
Lysosomes
3d
single
lysosomes Residual bodies are nothing but secondary lysosomes with undigested wastes. The digested materials are diffused into the cell cytoplasm through the lysosomal membrane. (Ref: www.sivabio.50web.com)
Physiology
General physiology
56faf4d2-8751-4867-9709-bba9420bdd1b
Measure of communicability of a disease -
Case fatality rate
Secondary attack rate
Sullivan index
Incubation period
1b
single
Ans. is 'b' i.e., Secondary attect rate Secondary attack rateo SAR is defined as "the number of exposed persons developing the disease within the range of incubation period, following exposure to primary caseSAR =No of exposed persons developing disease within the range of the incubation period-------------------------...
Social & Preventive Medicine
Infectious Disease Epidemiology
de225073-c6ce-4a1c-8815-5446c2a87384
In Von Hippel-Lindau Syndrome, the retinal vascular tumours are often associated with intracranial hemangioblastoma. Which one of the following regions is associated with such vascular abnormalities in this syndrome'?
Optic radiation
Optic tract
Cerebellum
Pulvinar
2c
single
Answer is C (Cerebellum) Von Hipple-Lindau Syndrome is associated with haemangioblastomas of cerebellum, spinal cord, medulla or pons.
Medicine
null
6f299673-f4a7-45b6-acfa-b15c564e923b
Signature fracture of skull is seen in
Gutter fracture
Depressed fracture
Ring fracture
Sutural seperation
1b
single
DEPRESSED SKULL FRACTURE It is a common neurosurgical problem among the head injuries. It means fracture depression is more than the depth of inner table of the skull. Investigations: CT scan. Problems in depressed fracture Tear in the dura beneath Haematoma in the deeper plane Injury to the cerebrum Injury to the veno...
Surgery
Trauma
2ed32ab4-6f3c-4627-beb6-9f63d59c2319
True about intrauterine fetal death (IUD) :
Gas bubbles in great vessels
Amniotic fluid volume
Overlapping of skull bone
All of the above
3d
multi
Ans. is a, b and c i.e. Gas bubbles in great vessels; Overlapping of skull bone; and Decreased amniotic fluid volume
Gynaecology & Obstetrics
null
81686685-b157-43c5-be11-d5eb42f7d26f
Tetracycline inhibits protein synthesis by?
Inhibiting initiation and causing misreading of mRNA
Binding to 30 S subunit and inhibits binding of aminoacyltRNA
Inhibiting peptidyltransferase activity
Inhibiting translocation
1b
single
Ans. is 'b' i.e., Binding to 30 S subunit and inhibits binding of aminoacyl tRNA Tetracycline interact with small ribosomal subunits, blocking access of aminoacyl- tRNA to the mRNA-ribosome complex.
Pharmacology
null
3baceec1-872b-477b-b185-91e45c4e9f42
Adverse effects of losaan are all EXCEPT -
Angioedema
Cough
Hyperkalemia
Headache
0a
multi
Ans. is 'a' i.e., Angioedema
Pharmacology
null
9502ffe4-606d-4869-972a-16d8b351f5d2
Muscle's of anterior compament of leg is/ are:
Peroneus teius
Peroneus brevis
Peroneuslongus
Flexordigitorumlongus
0a
single
Ans. (a) Peroneus teiusThe 4 muscles in the anterior compament of the leg are- the tibialis anterior, extensor digitorum longus, extensor hallucis longus, and fibularis(Peroneus) teius
Anatomy
null
a78e87fc-66e6-4860-ab88-a22fb60fb9a6
Albinism is a genetic disease that results in incomplete metabolism of:
Histidine
Cystine
Tyrosine
Alanine
2c
single
null
Biochemistry
null
f51891de-170b-4f00-9f25-24bc19ea5c16
40 years male with spherophakia is at risk for developing
Phacolytic glaucoma
Phacoanaphylactic glaucoma
Phacomorphic glaucoma
Obscuration of disc margins
2c
single
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 248) Phacomorphic glaucoma is an acute secondary angle-closure glaucoma caused by:Intumescent lens i.e., swollen cataractous lens due to rapid maturation of cataract or sometimes following traumatic rupture of the capsule is the main cause of phacomorp...
Ophthalmology
Glaucoma
c07c2a31-19c3-47be-b282-4370d0fbe971
Crystalline Lens is derived from (JIPMER May 2019)
Surface ectoderm
Neuroectoderm
Mesoderm
Endoderm
0a
multi
- Eye ball have contribution from several structures - Neural plate ectoderm forms Neural tube form - CNS which have diencephalon pa of brain aExtension of diencephalon (optic sulcus) into eyeball form retina (optic cup) & optic nerve (optic stalk) - Neural plate ectoderm also forms - epithelium of ciliary body & iris ...
Anatomy
JIPMER 2019
dd3ef3e0-c495-47a8-ad60-78ff4007aca1
Morbid jealousy is associated with which addiction?
Alcohol
Heroin
LSD
Charas
0a
single
Ans. is 'a' i.e., Alcohol Morbid jealousy (Pathological jealousy)* Also referred to as delusional jealously, obsessive jealousy and Othello syndrome. This condition occurs when a person feels an unreasonable fear that a partner has been unfaithful, is presently unfaithful, or plans to be unfaithful.* Morbid jealousy ca...
Psychiatry
Substance Abuse
7521c6ec-4921-42de-a95d-4d7d99c43071
Tripod fracture is the name given for
Zygomatic fracture
Maxillary fracture
Mandibular fracture
Temporal fracture
0a
single
Zygoma fracture is also known as tripod fracture. Clinical features of zygoma fracture Considerable swelling over zygomatic arch is common and makes clinical diagnosis more difficult. Flattening of malar prominence. Step-deformity of infraorbital margin. Anaesthesia in the distribution of infraorbital nerve. Trismus, d...
ENT
null
9c88fbaf-d698-4b43-87bb-18bc2f6ef785
Which of these are seen on Romanowsky stain
Cabot ring
Basophilic strippling
Howell_jolly bodies
All of the above
3d
multi
Ref : PJ Mehta 16/e p372,T. Singh 1/e p34 Ref Robbins 9/e pg 24 Romanowsky dyes are used for staining blood films,They are made up of combination of acid and basic dyes. The nucleus and neutrophils granules are basophilic and stains blue.hemoglobin is acidophilic and stains red. Various modification available are leish...
Anatomy
Haematology
e5f5b70f-55e3-4ba4-b60d-f9d557493af9
Most common type of congenital adrenal hyperplasis is
11 β Hydroxylase deficiency
21 Hydroxylase deficiency
17 α Hydroxylase deficiency
None of the above
1b
multi
null
Pediatrics
null
361163c3-3124-4fbe-8c49-adfc9348f3a4
Kelly's medium is used in the isolation of -
Leptospira
Borrelia
Bartonella
Brucella
1b
single
null
Microbiology
null
65f2c68a-63fd-4427-9e1a-0c9512f05b50
In all of the found except:
Measles
Typhoid
Hepatitis B
Gonorrhea
0a
multi
Ans. (a) Measles cZef Park 22/e, p 154 In measles and whooping cough only cases are found with no carriers. Chronic carriers seen in: Typhoid Dysentery Hepatitis B Cerebrospinal meningitis Malaria Gonorrhea
Microbiology
null
27994773-97ee-40af-91da-3c21e12794e2
Which is the drug of choice for prophylaxis of meningococcal meningitis in pregnancy:
Penicillin
Ceftriaxone
Rifampicin
Ampicillin
1b
single
N. meningitidis is dangerous because it can cause Waterhouse Friderichsen syndrome & Addisonian crisis So, chemoprophylaxis is recommended Ceftriaxone as a single IM or IV injection is highly effective in carriage eradication and can be used at all ages and in pregnancy
Medicine
Bacterial infection
8ab6f79c-285d-4ef6-b996-a2020ec456d5
Regarding pleomorphic adenoma of salivary gland true statement (s) is /are
Parotid gland is most commonly involved
Malignant transformation does not occur
Also called adenolymphoma
More commonly found in Men than Women
0a
multi
Eighty percent salivary neoplasms are in the parotids of which 80% are benign.Pleomorphic adenoma is more common in parotids(80%).It is more common in females in a ratio of 3:1.It is also called as mixed salivary tumour.Malignant transformation can occur in 3-5% in early tumours and 10% in long duration tumours.(15 or ...
Surgery
Head and neck
290758a9-de76-47af-a007-e40b65481865
Least failure in sterilization occurs with :
Falope ring
Bipolar cautery
Unipolar cauterisation
Hulka clip
2c
single
The success rates are best when clips and rings are used and worst with electrocoagulation. TEXTBOOK OF GYNECOLOGY SHEILA BALAKRISHNAN SECOND EDITION PAGE NO 393
Gynaecology & Obstetrics
Contraception
4b8b3b7e-e15d-4b59-aaa7-35a2f79b4657
Bowel can get strangulated in all of the following space, EXCEPT:
Rectouterine pouch
Ileocolic recess
Paraduodenal recess
Omental bursa
0a
multi
Omental bursa, paraduodenal recess and ileocolic recess are peritoneal recesses. Peritoneal recesses These are small pockets of the peritoneal cavity enclosed by small, inconstant folds of peritoneum. These are best observed in fetuses and are mostly obliterated in adults. Sometimes they persists to form potential site...
Surgery
null
e35a1308-a3b7-4b97-90dd-dc0dd259b112
All are true about aspirin poisoning except
Acidosis
Hypothermia
Dehydration
Oliguria
1b
multi
null
Medicine
null
99f46a2c-82a3-43fe-b02e-ad47b6fddc7c
Low grade Central Nervous System tumour among the following is
Diffuse astrocytoma
Anaplastic astrocytoma
Glioblastoma multiforme
Meningioma
3d
single
(D) Meningioma # SPECTRUM OF CNS TUMORS range from Diffuse astrocytoma (grade ll/IV) Anaplastic astrocytoma (grade lll/IV) Glioblastoma (grade IV/IV)> Most meningiomas have a relatively low risk of recurrence or aggressive growth, and so are considered WHO grade l/IV.
Pathology
Misc.
27b544b4-b6cf-43b6-82e3-9efe6183ae97
The risk of complex hyperplasia of endometrium with atypia progressing to malignancy in a postmenopausal woman is :
3%
8%
15%
29%
3d
single
WHO classification of Progression to Carcinoma The risk of complex hyperplasia of endometrium with atypia progressing to malignancy in a postmenopausal woman is 29% Reference : Textbook of Gynaecology; Sheila balakrishnan; 2nd edition; pg no: 248
Gynaecology & Obstetrics
Gynaecological oncology
bd6e181f-88ca-4a88-a218-90b445f4426e
A female presents with 3 cm painless ulcer with raised edges on labia majora. Most common cause is: (E. REPEAT 2013)
Syphilis
Gonorrhea
Herpes
Chlamydia trachomatis
0a
single
Ref: E s sent to Is in Dermatology, 1st editionExplanation:* Presence of 3 cm ulcer with raised edges in the labia majora suggests Syphilis. (See the following table) SyphilisGranuloma Inguinale (Donovanosis)Chancroid(Soft sore. Soft Chancre, Ulcus molle)LymphogranulomaVenereumEtiologyTreponema pallidumCalymmatobacteri...
Gynaecology & Obstetrics
Specific Infections
22eb85c4-160f-47e6-8a77-a8982caa052f
Regarding stones in gall bladder the following are true except -
Mixed stones are common in the west
In Saints Triad diverticulosis of colon and hiatus hernia coexist
Is a risk factor in the development of GB carcinoma
90% of GB stones are radioopaque
3d
multi
null
Surgery
null
62dab497-b15c-493b-958d-1eb3668c55d9
Skeletal frame work of a cell is maintained by:
Nucleus
Microtubules
Ribosomes
Mitochondria
1b
single
Ans. (b) Microtubules(Ref: Ganong, 25th ed/p.39)Microtubules provide structural support that can determine the shape of the cell and resist forces that tend to deform it
Physiology
General
47632585-cfa0-428d-b9f1-f7667a860b29
systematic desensitization was introduced by
seligman
joseph wolpe
lorenz
skinner
1b
single
SYSTEMATIC DESENSITIZATION JOSEPH WOLPE Joseph Wolpe gave the concept of systematic desensitization This is a treatment used in phobia In phobia there is a conditioned fear response to aversive neutral stimulus and avoidance of that response leads to phobia Whenever there is a fear response there is stimulation of symp...
Anatomy
Treatment in psychiatry
3d833c6a-d2c6-4445-9718-8afc47e4c32b
Haabs striae are seen in-
Buphthalmos
Keratoglobus
Trachoma
Keratoconus
0a
single
Haabs striae -Tears and breaks in descemets membrane . These occur because Descemt's membrane is less elastic than the corneal stroma. Tears are usually peripheral, concentric with the limbus and appear as lines with double contour. Ref:Comprehensive ophthalmology-AK Khurana 6th edition chapter-10 page no:226
Ophthalmology
Glaucoma
c0b30e3c-6d1d-464e-831a-5e708b3436b4
Which of the following is not a minor diagnostic criteria for multiple myeloma?
Lytic bone lesions
Plasmacytosis greater than 20%
Plasmacytoma on biopsy
Monoclonal globulin spike on serum electrophoresis of > 2.5 g/dl for IgG, >1.5 g/dl for IgA
2c
single
Ans. (c) Plasmacytoma on biopsy(Ref: Wintrobes 12th/pg2377)Durie and Salmon criteria for diagnosis of Multiple myeloma.A minimum of 1 major and 1 minor criterion needed, although (1) + (a) is not sufficient, or 3 minor criteria that must include (a) and (b).However, International myeloma working group 2011 has revised ...
Pathology
Misc. (W.B.C)
af379a52-6e0c-48b9-902a-9e0e04e2f746
Frequency polygon is obtained by joining the points of
Bar diagram
Complete bar diagram
Multiple bar diagram
Histogram blocks
3d
single
Ans. d (Histogram blocks) (Ref. Park PSM 22nd/ 788; Methods in Bio-statistics, by B. K. Mahajan 6th/p. 23)Quantitative data is presented by the following graphsQualitative or discrete or enumeration data is presented by the following graphs:# Histogram.# Bar diagram# Frequency polygon.# Pie or sector diagram# Frequency...
Social & Preventive Medicine
Biostatistics
c40f18bd-a297-4dea-b35a-c91775618a64
Wave One is classified as
Sgp31
Sgp32
Sgp33
None of the above
2c
multi
null
Dental
null
e32cfbed-a15f-470d-a5c0-255b14e59d68
Following are hepatotoxic anesthetic agents except-
Halothane
Chloroform
Ether
Propofol
3d
multi
Ans. is 'd' i.e.. Propofol o Following are the groups of hepatotoxic anesthetic agents:i) Group I: Drugs with well known hepatotoxic potential and containing Chlorine or bromine. Eg: chloroform,ii) Group II: Drugs which contain fluorine Eg: halothane, methoxyflurane. o Desflurane, enflurane, sevoflurane, isoflurane, ni...
Anaesthesia
Miscellaneous (Local and Regional Anesthesia)
91ea7b39-e433-42d9-bab5-3e23d5a4aa39
Normal glomerular filtration rate is -
50 ml/min
125 ml/min
250 ml/min
500 ml/min
1b
single
In man, resting glomerular filtration rate is about 125 ml/min (lSOL/day), the renal plasma flow is about 600 ml/min. Thus about one-fish (20%) of plasma passing through kidney is filtered„ i.e., a fraction of renal plasma flow that is filtered (filtration fraction)
Physiology
null
48b40ad2-8e02-4836-9211-15440d7dffe9
An elderly male presents with one episode of gross haematuria. All of the following investigations are recommended for investigating this patient except:
Cystoscopy
Urine microscopy for malignant cells
Urine tumor markers
Intravenous Pyelogram
2c
multi
Answer is C (Urine tumor markers) Urine tumor markers are the single best answer of exclusion as these are neither sensitive nor specific enough to replace cystoscopy and cytology. 'Individuals older than 40 years of age who develop haematuria , should have a urine specimen for cytology and undergo cystoscopy and imagi...
Medicine
null
a9efe179-cf48-49f1-bed7-ee04a79e1453
Cold caloric test stimulates
Cochlea
Lateral semicircular canal
Posterior semicircular canal
All
1b
multi
Stimulation of semicircular canal produces nystagmus and the direction of nystagmus is determined by the plane of the canal being stimulated. In cold caloric test, the lateral semicircular canal is stimulated. (Ref: Diseases of EAR, NOSE AND THROAT by PL DHINGRA - 6th Edition)
ENT
Ear
6f596637-11fe-490e-81be-963f0362d990
Drug resistant in tuberculosis is due to ?
Transformation
Transduction
Conjugation
Mutation
3d
single
Drug resistance in M.tb is by Mutation in Chromosomes Metabolic defects occur as a result of mutation Eg - M.tb is normally catalase +ve INH resistant M.tb are Catalase -ve
Microbiology
General Microbiology Pa-2 and Pa-3 (Sterilization and Bacterial Genetics)
8baa5529-4a6e-47ed-af83-aa261396e463
Cells present in Cerebellar coex are all except?
Purkinje
Bipolar
Granule
Golgi
1b
multi
There are 5 types of neurons present in cerebellar coex:- Granule cell- Golgi cell- Basket cell - Stellate cell- Purkinje cellBipolar neurons are less common. A single axon and dendrite arise at opposite poles of the cell body. Their cell bodies are located in the retina, the olfactory epithelium, and the cochlear and ...
Anatomy
null
83c1e444-a250-4033-9209-cd22f7b62fb8
Telefono is
Pulling of hair
Beating on soles
Beating on ears
Beating on fingers
2c
single
TELEFONO consists of repeated slapping of the sides of the head by open palms of the assailant this may cause rupture of ear drums. Ref : internet sources
ENT
All India exam
b4db661b-d453-4350-a7f3-f5dead0aa450
Adipocere is likely to occur in -
Warm humid climate
Dry hot climate
Burial in sandy soil
Extreme cold
0a
single
null
Forensic Medicine
null
ce965bf6-bbb6-400b-8c95-062091a642e0
Rituximab is a targeted antibody against -
CD 20
CD 22
CD 34
CD 55
0a
single
Ans. is 'a' i.e., CD 20 * Rituximab is a targeted antibody against cell surface molecule CD-20, i.e. Rituximab is anti CD-20 antibody.* It is used in:i) B-cell lymphomas Low grade lymphomas, mantle cell lymphomas, relapsed aggressive B cell lymphomas, CLLii) SLEiii) Rheumatoid arthritis
Pharmacology
Immunomodulator
30e81409-3e3c-4e5f-8684-43eff5a85f17
Enzyme that protects the brain from free radical injury is
Myeloperoxidase
Superoxide dismutase
MAO
Hydroxylase
1b
single
Superoxide dismutase ref Robbins 7/e p17 , Harrison 17/e p 2572 ,9/e p48.
Anatomy
General anatomy
b4bbe6ff-a817-48b1-b881-374deb05dcf1
Fastest acting antithyroid drugs ?
Iodides of Na/ K
Propylthiuracil
Methimazole
Nitrates
0a
single
Ans. is 'a' i.e., Iodides of Na Iodine and Iodides Iodine is the fastest acting thyroid inhibitor Most impoant action is inhibition of hormone release (thyroid constipation); but all facets of thyroid synthesis may be affected. Excess iodide inhibits its own transpo in thyroid cells and may alter the redox potential of...
Pharmacology
null
be035d9e-8a60-4a38-af39-24ea8966cae3
Clinically in the non-injured eye, sympathetic ophthalmitis may manifest as:
Acute plastic iridocyclitis
Neuroretinitis
Choroiditis
All of the above
3d
multi
Ans. All of the above
Ophthalmology
null
ec6babf8-6e3e-49af-aa46-c746a914850b
An 8 years old child has left sided flank pain and mental retardation. On ultrasound, a hyperechoic lesion in the right kidney and multiple lesions in the liver are noted. CT examination of the abdomen revealed -50 to -80 HU density of these lesions. The most probable diagnosis is:
Tuberous sclerosis
Hereditary hemangioblastoma
Autosomal recessive polycystic kidney disease
von Hippel-Lindau syndrome
0a
single
Answer- A (Tuberous sclerosis)AML is a benign clonal neoplasm consisting of varying amounts of mature adipose tissue, smooth muscle and thick-walled vessels.
Surgery
null