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135
d4039ef1-001a-49a0-8770-462c7f4db81e
Which of the following is not true about hypoxanthineguanine phosphoribosyl transferase?
Predominantly present in liver
Involved in purine metabolism
PRPP is the substrate required
Its deficiency leads to Lysch Nyhan disease.
2c
multi
"SALVAGE REACTIONS" CONVE PURINES & THEIR NUCLEOSIDES TO MONONUCLEOTIDES Conversion of purines, their ribonucleosides, and their deoxyribonuc]eosides to mononucleotides involves so- called "salvage reactions" that require far less energy than de novo synthesis. The more impoant mechanism involves phosphoribosylation by...
Surgery
null
594acf87-5fd5-47fd-b789-93ffe764132b
Mercury affects which pa of the kidney ?
PCT
DCT
Collecting duct
Loop of Henle
0a
single
Ans. is 'a' i.e., PCT
Pathology
null
4f6ff14a-f318-4e59-ae11-09b0fb5909a3
Primary amenorrhoea is a feature of all EXCEPT: September 2012
Turner's syndrome
Stein-Leventhal syndrome
Rokitansky-Kustner-Hauser syndrome
Kallman syndrome
1b
multi
Ans. B i.e. Stein Leventhal syndrome
Gynaecology & Obstetrics
null
8991e120-b3d7-40d2-bf55-9f415d22e93a
A 45 year old female presents with symptoms of acute cholecystisis . On USG there is a solitary gall stone of size 1.5 cm. Symptoms are controlled with medical management. Which of the following is the next most apppropriate step in the management of this patient.
Regular follow up
IV Antibiotics
Laparoscopy cholecystectomy immediately
Open cholecystectomy immediately
2c
multi
Laparoscopic cholecystectomy is the gold standard treatment for gallstones,especially with symptoms or complications like acute cholecystitis.Some surgeons advocate urgent operation on a routine measure in cases of acute cholecystitis..Good results are obtained when the operation is undeaken within 5-7 days of the onse...
Surgery
G.I.T
3de5dd79-52f9-4365-a310-0e3a3a4f6d21
Prognosis of breast carcinoma is best determined by ?
Oestrogen \/ progesteron receptors
Axillary lymph node status
Clinical assessment
CT
1b
single
.Treatment of breast cancer depends on clinical stage of disease and stagings involves assessing the most common lymph node draining the breast:ie axillary lymph node. according to TNM staging, the nodes are scored on 1 to 3 score 1 :no nodal involvement score 2: one to three nodes involved score 3:four or more nodes i...
Surgery
Endocrinology and breast
a21b7844-9dae-4ab5-a61e-ab3da03efa83
A 57-year-old man presents with hemoptysis and generalized weakness. His symptoms began with small-volume hemoptysis 4 weeks ago. Over the past 2 weeks, he has become weak and feels "out of it." His appetite has diminished, and he has lost 10 lb of weight. He has a 45-pack-year history of cigarette smoking. Physical ex...
Bronchial carcinoid
Adenocarcinoma of the lung
Small cell carcinoma of the lung
Lung abscess
2c
multi
Hyponatremia in association with a lung mass usually indicates small cell lung cancer (SCLC) with inappropriate antidiuretic hormone (ADH) production by the tumor. About 10% of lung cancers present with a paraneoplastic syndrome. Tumors producing ADH or adrenocorticotropic hormone (ACTH) are overwhelmingly SCLCs, which...
Medicine
Respiratory
28e46332-bccb-4ed3-a739-b1fc0e8e73ed
Private Doctor refusing to treating a case of sexual offence and referring to govt hospital is
Not an offence
Punishable under 166 B IPC
Punishable under 357 (c) Cr P C
Punishable under 327 (c) Cr P C
1b
single
Treatment of rape victim and information to police: All hospitals, public or private, should immediately provide first-aid or medical treatment, free of cost, to the survivor/victim of rape or acid attack, and should immediately inform the police . Denial of treatment of such victims is punishable under Sec. 166-B IPC ...
Forensic Medicine
Legal sections
80222cc1-aaf2-4f51-a281-922eb47c25f7
Which of the following is true about female health worker?
Acts at PHC level
Covers a population of 5000 population
Chlorinates well at regular intervals
Makes at least 3 post natal visits for each delivery
1b
multi
ANSWER: (B) Covers a population of 5000 populationREF: Park 18th ed p. 809-810Under the multipurpose health worker scheme one health worker male and one health worker female are posted at each sub-centre, and are expected to cover a population of 5000.Female health worker makes at least 2 post natal visits.Chlorinating...
Social & Preventive Medicine
Community Healthcare
3dca8bb7-27e9-406f-b9ff-89d3b4c9d14f
One unit of fresh blood raises Hb% ( Hemoglobin concentration ) by
0.1gm%
0.5 gm %
1gm%
2 gm%
2c
single
Single unit of whole blood raises Hb by 1 gm% and Hematocrit by 3% More than 70% of transfused cells will be ble after 24 hours Ref: Harrison's 19th edition Pgno :138
Anatomy
General anatomy
fa8e120d-c445-4a54-8c27-64742ffc0e64
Coagulative necrosis is seen in:
Brain
Breast
Liver
All
2c
multi
Coagulative necrosis is a form of necrosis in which the underlying tissue architecture is preserved for at least several days after the death of cells in the tissue. The affected tissues take on a firm texture. Presumably, the injury denatures not only structural proteins but also enzymes, thereby blocking the proteoly...
Pathology
null
d1210017-9967-4c6b-bc25-bcd6f5ee1f41
Incubation period of scabies is:
7 days
2 weeks
4 weeks
2-3 days
2c
single
Scabies - Causative agent: Sarcoptes Scabies Var Hominis Incubation Period: 3-4 weeks after the infection is acquired. If pt. reinfested- ICP is 2 days
Dental
Scabies and other infestations
7e6ff31f-bb96-4d86-b673-b898767134d4
Which of the following phospholipid serves as a marker of apoptosis
Phosphatidylinosital
Phosphatidyl serine
Phosphatidyl choline
Phosphatidyl ethanolamine
1b
single
Phosphatidyl serine is normally present on inner mitochondrial membrane, flipping of it to the outer mitochondrial membrane is seen in apoptosis.
Biochemistry
null
c70efef7-813f-4b61-a9d1-dd7a6109c380
The triple P procedure for placenta percreta involves all except:
Pelvic devascularization
Placental localization using USG
Peripartum hysterectomy
Myometrial excision for placental nonseparation
2c
multi
Ans. is c, i.e. Peripartum hysterectomyRef Fernando Arias 4/e, p 396Triple P procedure has been developed for placenta percreta as a conservative surgical alternative to peripartum hysterectomy. It consists of following 3 steps:1. Perioperative placental localization and delivery of fetus via transverse uterine incisio...
Gynaecology & Obstetrics
Complication of 3rd Stage of Labour
397ff8f7-89f8-4127-9e94-e7ce5dc41705
Routine second look endoscopy in the setting of non variceal upper GI bleeding is recommended in patients with:
Rockall score 2
Treated with epinephrine injection alone
Cardiac disease
Renal disease
1b
multi
Routine second look endoscopy in the setting of non variceal upper GI bleeding is recommended in patients with Patients who had an incomplete initial endoscopic examination Patients with clinically significant rebleeding Patients who are treated with epinephrine injection alone Ref: Sleisenger and Fordtran's, E-9, P-29...
Medicine
null
8ed3fc5f-2596-4ad4-981a-2b03b4ab3f4c
Most common paranasal sinus involved by Fibrous dysplasia is?
Maxillary sinus
Frontal sinus
Ethmoid sinus
Sphenoid sinus
0a
single
ANSWER: (A) Maxillary sinusREF: Ballenger's Otorhinolaryngology: Head and Neck Surge by James Byron Snow, PhillipA. Wackym, John Jacob Ballenge centennial ed p. 506Indirect repeat ENT 2012 Session 1 (see details of Fibrous dysplasia)See APPENDIX-49 "PARANASAL SINUSES" APPENDIX - 49Paranasal Sinuses:Paranasalsinus(PNS)S...
ENT
Nose and PNS
5b98bc47-99f0-471a-9b86-894f77ab1681
A child is spinned around by holding his hand by his father. While doing this the child started crying and does not allow his father to touch his elbow. The diagnosis is -
Pulled elbow
Radial head dislocation
Annular ligament tear
Fracture olecranon process
0a
multi
This is case of pulled elbow and a dramatic cure is achieved by forcefully supinating and then flexing the elbow.
Orthopaedics
null
6d941de5-241b-412d-859a-16e5ada8219a
Monitoring of rate of occurrence of specific conditions to assess the stability or change in health levels of a population is known as:
Epidemiological surveillance
Active surveillance
Passive surveillance
Sentinel surveillance
3d
single
null
Dental
null
9d56e553-bda9-4f5f-b9ea-21f474f28592
A 40 yr old male has a rash over groin with demarcated peripheral scaling and central clearing. It could be due to: September 2005
Candidiasis
Malassezia furfur
Trichophyton
Aspergillosis
2c
single
Ans. C: Trichophyton Tinea cruris, a pruritic superficial fungal infection of the groin and adjacent skin, is the second most common clinical presentation for dermatophytosis The most common etiologic agents for tinea cruris include Trichophyton rubrum and Epidermophyton floccosum; less commonly Trichophyton mentagroph...
Skin
null
4f6f0296-e9d7-4e87-aab0-3feabbfe70bb
Gnarled enamel is seen in:
Proximal surface of tooth
Cervical region of tooth
Cusp tips of tooth
All of the above
2c
multi
null
Dental
null
9aa365b1-e867-4a53-88e8-92de7e94db22
Drug used for penile erection -
Sildenaphil
Apomorphine
Papaverine
All of the above
3d
multi
Ans. is'd'i.e., All of the above[Ref KDT fl/e p. 303-304 6 &/e p. 296; Katzung LLth/e p. 197)Drugs used in erectile dysfunctionPhosphodiesterase-S inhibitors (Sildenafil, Todafil, Vardenafil)Alprostadil (Prostaglandin El)
Pharmacology
null
b3c3e152-370c-48a4-8a4c-20349dec5ffc
pH of vagina in pregnancy is -
4.5
7
8.5
11
0a
single
Ans-A i.e., 4.5 Physiological chanses in vaeina durine pres nancy:o The vaginal walls become hypertrophied, edematous and more vascular.o Increased blood supply to venous plexus surrounding the was Us gives bluish colouration of the mucosa jacquemier's sign).o The length of the anterior vaginal wall is increased.o The ...
Unknown
null
a97ac2cb-e48a-4f32-aae6-778ef92d3554
Drug of choice of trachoma is-
Penicillin
Sulfonamide
Tetracyline
Chloramphenicol
2c
single
1. Topical therapy regimes. It is best for individual cases. It consists of 1 percent tetracycline or 1 percent erythromycin eye ointment 4 times a day for 6 weeks or 20 percent sulfacetamide eye drops three times a day along with 1 percent tetracycline eye ointment at bed time for 6 weeks. 2.Systemic therapy regimes. ...
Ophthalmology
Conjunctiva
73b98d3a-13ab-4b46-989b-f07a0cf6d2f2
The effect of sucking habit
Is less favourable in vertical growth tendency than horizontal growth tendency.
Is less favourable in horizontal growth tendency than vertical growth tendency.
Any of the above can be true
None of the above
0a
multi
null
Dental
null
974f6659-da59-4d05-85c6-29fc6c0be0d7
In maple syrup disease, the amino acids excreted in urine are, EXCEPT:
Valine
Leucine
Isoleucine
Phenylalanine
3d
multi
Maple syrup urine disease (MSUD), or branched-chain ketoaciduria, is caused by a deficiency in activity of the branched-chain -keto acid dehydrogenase Inborn error of metabolism of valine leucine and isoleucine associated with gross mental deficiency. Branched chain alpha-keto acid dehydrogenase is located in the inner...
Biochemistry
null
1d6262e1-9f3c-45e1-ba8d-001e806ecf46
The difference between leukemia and leukemoid reaction is done by -
Leukocyte alkaline phosphatase
Immature cells
Total leukocyte count
E.S.R.
0a
single
Leukemoid reaction is defined as a reactive excessive leukocytosis in peripheral blood resembling that of leukemia in a subject who doesnot have leukemia. Leucocyte alkaline phosphatase (LAP) score in the cytoplasm of mature neutrophils is high in leukaemoid reaction whereas reduced in CML .It is very useful to disting...
Pathology
Haematology
dd8f98e0-5cd9-48b8-9243-e7f77c324f7a
A 32 year old woman presents with complaints of several months of burning substernal chest pain exacerbated by large meals, cigarettes, and caffeine. Her symptoms are worse when she lies on her back, especially when sleeping at night. Antacids often improve her symptoms. This patient is at risk for which of the followi...
Cardiac ischemia
Columnar metaplasia of the distal oesophagus
Mallory-Weiss lesion in the esophagus
Squamous cell carcinoma
1b
multi
This woman likely suffers from reflux esophagitis, a condition in which the lower esophageal sphincter (LES) does not adequately prevent acidic gastric contents from refluxing back into the distal esophagus. Most commonly, there is a defect in the LES mechanism itself, in addition to secondary causes such as pregnancy ...
Pathology
null
5207ba78-76dd-41d7-8df4-b8dac55c6e65
Supra - amohyoid neck dissection is
Lymph nodes I - V levels removed
Lymph nodes I - III levels removed
Lymph nodes I - V level removed along with IJV, SCM and spinal accessory nerve
Lymph nodes I - III levels removed along with IJV SCM and spinal accessory nerve
1b
single
null
ENT
null
e166daf6-60c1-45bd-8031-225cd2b4ab6c
Which of the following anticholinergic is used for peptic ulcer disease
Dicyclomine
Methacoline
Pirenzepine
Aclidinium
2c
single
Pirenzepine is a M1 receptor antagonist. Acetyl choline acts on M1 receptors present on gastric glands to increase acid secretion and Pirenzepine is used to treat peptic ulcer disease by blocking these receptors.
Pharmacology
null
98033661-37b8-48f6-a702-ee5b9b6cc217
According to Miller's classification of increased tooth mobility, grade 3 would be
0.1 to 0.2 mm in horizontal direction
Upto 1mm in horizontal direction
> lmm in horizontal direction
Mobility in horizontal and vertical direction
3d
single
null
Dental
null
23f93efc-0a86-4f19-a735-465ef995b4e6
A pt. presents with hematuria of several days and dysmorphic RBC casts in urine. The site of origin is :
Kidney
Ureter
Bladder
Urethra
0a
single
Ans. is 'a' ie kidney " Isolated microscopic hematuria can be a manifestation of glomerular disease. The RBCs of glomerular origin are often dysmorphic."" Hematuria with dysmorphic RBCs, RBC casts and protein excretion > 500 mg/day is virtually diagnostic of glomerulonephritis."SoDysmorphic RBCs - origin is kidney*RBCs...
Surgery
Kidney & Ureturs
19292bb2-dcd7-4ad4-8583-14ea0157c534
All cause brain lesions except
Giardiasis
Tuberculosis
Cysticercosis
Bacteroides
0a
multi
(A) Giardiasis # G. lamblia is seen typically within the crypts in duodenum> It does not invade tissues, but remains tightly attached by means of the sucking disc to the epithelial surface in the duodenum and jejunum.> The diarrhoea in some cases may be steatorrhoeic with excess mucus and fat, but no blood.> Children m...
Microbiology
Misc.
8fad093d-bc0d-4755-a903-5985857371d0
Commonest cause of raised serum calcium is -
Ecotopic secretion
Parathyroid hyperplasia
Parathyroid adenoma
Parathyroid carcinoma
2c
single
Ans. is 'c' i.e., Parathyroid adenoma o Primary hyperparathyroidism is the most common cause of hypercalcemia overall. o The frequency of the various parathyroid lesions underlying the hyperfunction is as follows : ? Parathyroid adenoma - 75% to 80% Primary hyperplasia - 10% to 15% Parathyroid carcinoma- < 5% o After h...
Pathology
null
f6ef2d56-11af-45d1-8954-e505a3dd9800
MAC stands for
Minimum alveolar concentration
Minimal analgesic concentration
Minimal anaesthetic concentration
Maximum alveolar concentration
0a
single
Minimum alveolar concentration is defined as the alveolar concentration of an inhaled anesthetic agent that prevents movement in 50% of patients in response to a standardized surgical stimulus. Low MAC - High potency MAC values of adult Halothane: 0.75 Sevoflurane: 2.0 Isoflurane: 1.2 Desflurane: 6.0 Enflurane: 1.7 Xen...
Anaesthesia
General anaesthesia
3ca9c991-13cb-4106-be5e-3e27351ff248
Hecht's pneumonia is a complication of
Measles
Mumps
AIDS
Mycoplasma
0a
single
Hecht's pneumonia is  a giant cell pneumonia in immunodeficient people,rare complication of measles.
Microbiology
null
e6ddaefb-71ce-4819-8c04-a6aaea85321f
Deflouridating material is:
Duraphat
Fluorprotector
Brudevold's solution
alumina
3d
single
null
Dental
null
37fab6fd-1212-47a2-9138-a20634367df3
Suicide is most common in -
Depression
Alcohol dependence
Dementia
Schizophrenia
0a
single
Ans. is 'a' i.e., Depression Causes/Risk factors for suicidePsychiatric disorders : - Depression (most common), alcoholism (2nd me), Drug/Substance dependence, Schizophrenia, Dementia.Physical illness : - Cancer, AIDS, Multiple sclerosis, Head trauma.Psychosocial factors : - Failure in love, marital difficulties, famil...
Psychiatry
Symptoms & Signs
82b36b54-a189-4fe9-aec9-5335910808e5
Most of the drug resistance occurs due to:(1996)
Transduction
Translation
Mutation
Conjugation
3d
single
Ans: d
Microbiology
General
7a5b2d3e-8efa-4f30-ae49-91db4b5bc4d5
In leprosy which of the following is not seen – a) Abnormal EMGb) Voluntary muscle wastingc) Decreased proprioceptiond) Decreased response to tactile sensatione) Increased response to tactile sensation
a
ce
ac
ae
1b
single
Muscle deficit (voluntary muscle wasting) results in abnormal EMG. There is decreased response to tactile stimulation (not increased). Proprioception and vibration is not affected as leprosy spares posterior column
Dental
null
98cd1b84-4eeb-41e3-b6e0-94b7bb985b0b
Approximate magnitude of completed family size is denoted by
General fertility rate
Total marital fertility rate
Total fertility rate
General marital fertility rate
2c
single
null
Social & Preventive Medicine
null
c2a8aff7-6185-4b4a-96a7-e93ab39e38be
Which of the following antitussive can lead to hallucinations
Morphine
Dextromethorphan
Diphenhydramine
Aprepitant
1b
multi
Dextromethorphan is a NMDA antagonist used for Mild cough, which can lead to hallucination & addiction.
Pharmacology
null
43020e58-266b-4f02-a75c-9b9ba66cf5c3
A 19-year-old fell from a cliff when he was hiking in the mountains. He broke his fall by grasping a tree branch, but he suffered injury to the C8-T1 spinal nerve roots. Sensory tests would thereafter confirm the nature of his neurologic injury by the sensory loss in the part of the limb supplied by which of the follow...
Lower lateral brachial cutaneous nerve
Musculocutaneous nerve
Intercostobrachial nerve
Medial antebrachial cutaneous nerve
3d
multi
In a lesion of the lower trunk, or the C8 and T1 nerve roots, there is sensory loss on the medial forearm and the medial side of hand (dorsal and ventral). The medial cord is the extension of the lower trunk. The medial cord gives origin to the medial antebrachial cutaneous nerve, which supplies the T1 dermatome of the...
Anatomy
Upper Extremity
582bb9d7-0d54-4fef-932b-d91d2a8377c2
Impression plaster is
Hydrophobic
Hydrophilic
Not compatible in wet sulcus
Highly viscous
1b
single
null
Dental
null
377f5238-eed1-4d9e-b101-4b3f3c81f83e
Integrity of the optic nerve is tested by except :
Tangent Screen examination
VER
Perimetry
ERG
3d
multi
Electroretinography (ERG) measures the electrical response of the retina to flashes of light, the flash electroretinogram, or to a reversing checkerboard stimulus, the pattern ERG (PERG).All other test in the option tests the integrity of optic nerve. Perimetry or Tangent Screen examination is used to examine the centr...
Ophthalmology
null
fe6ea3d0-b587-4306-b7c6-5b0bd826be31
Which of the following cardiac complications may develop in a 33 year old woman with systemic lupus erythematosus (SLE) because of her underlying condition?
Hemorrhagic pericarditis
Infective endocarditis
Libman-Sacks endocarditis
Mitral valve prolapse
2c
single
Libman-Sacks endocarditis affects patients with systemic lupus erythematosus (SLE). Small granular vegetations consisting of fibrin develop on the undersurface of the leaflets of mitral and aoic valves. Fragments of vegetations may detach, resulting in embolism. Eventually, vegetations heal by organization of fibrin an...
Pathology
null
32dc13a3-2bd2-4caf-8a38-da5085e969af
Which is the first country in south east Asia to have eliminated trachoma?
India
Nepal
Bangladesh
Pakistan
1b
single
21 May 2018 - The World Health Organization (WHO) has validated Nepal for having eliminated trachoma as a public health problem - a milestone, as the country becomes the first in WHO's South-East Asia Region to defeat the world's leading infectious cause of blindness. Several criteria are used to assess a country's cla...
Ophthalmology
Disorders of Conjunctiva
66ba770d-331c-4d0c-b5e4-b23ba9dbf9b7
One of the following is a sure sign of rape :
Ruptured hymen in a girl aged 20 years
Presence of semen in the posterior fornix in a girl age 20 years
Presence of semen in the posterior fornix in a girl age 14 Years
Presence of semen in the posterior fornix in a married girl age 16 years
2c
single
C i.e. Semen in fornix in a girl < 14 years
Forensic Medicine
null
ac829992-fb3e-4f5d-8fbd-59b2db9240da
All of the following bases are present in DNA, EXCEPT:
Adenine
Guanine
Uracil
Thymine
2c
multi
DNA contains only four different bases: adenine (A), guanine (G), thymine (T), and cytosine (C). DNA exists as a double helix in which A is always paired with T, and G is always paired with C. RNA contains the ribonucleotides of adenine, guanine, and cytosine, it does not possess thymine. Instead of thymine, RNA contai...
Biochemistry
null
8162e3ed-a630-4c34-b98e-1cf2dbfdf966
The strain which is used for production of BCG vaccine at commercial level is
Danish-1331
Tween-80
Bacille Calmette Guerin
PPD-RT-23
0a
single
null
Social & Preventive Medicine
null
a9409109-57b2-48bf-b35d-b31a50849373
An auto rickshaw ran over a child's thigh, there is a mark of the tyre tracks, it is an example of: AIIMS 10
Patterned bruise
Patterned abrasion
Pressure abrasion
Graze abrasion
1b
single
Ans. Patterned abrasion
Forensic Medicine
null
1041089e-e1e3-41b4-b649-5a6ab9501892
Dilantain (Phenytoin) is known to cause:
Folic acid deficiency
Biotin deficiency
Thiamine deficiency
Riboflavin deficiency
0a
single
Folic acid deficiency
Pharmacology
null
6c02f669-8894-4786-bba1-2c8e695eb9c6
All the following muscles have dual nerve supply except
Subscapularis
Pectoralis major
Pronator teres
Flexor digitorum profundus
2c
multi
1) Flexor digitorum profundus is supplied by - (i) Medial half by ulnar nerve and Lateral half by anterior interosseous nerve(C8 , T1) ( branch of median nerve ). 2)Subscapularis is supplied by - Upper and lower subscapular nerves ( C5 , C6 ). 3) pectoralis major is supplied by - Medial and lateral pectoral nerves. 4)p...
Anatomy
Upper limb
1d7e6086-3182-4097-a5c5-05ef8e7b9aa1
One of the following is a characteristic of Henoch- Schonlein Purpura -
Blood in stool
Thrombocytopenia
Intracranial hemorrhage
Susceptibility to infection
0a
single
null
Medicine
null
6e7f20ea-f818-4208-a0f2-ca47b54acb1c
Essential atrophy of choroid is due to inborn error of metabolism of amino acid:
Cystine
Cysteine
Arginine
Ornithine E Lysine
3d
single
Ans. Ornithine E Lysine
Ophthalmology
null
a57990ca-d17a-4c9b-8a02-343f2cba2d55
The interior of right atrium is partially divided into two parts by -
Crista terminalis
Musculi pectinati
Fossa ovalis
Sinus venarum cavarum
0a
multi
Right atrium is divided into rough anterior and smooth posterior parts by crista terminalis.
Anatomy
null
2f7ac328-e4e1-468e-b0cd-16061c73856b
Anterolateral avulsion fracture of the distal tibial physis is known as -
Potts fracture
Tillaux frascture
Choparacture
Jones fractture
1b
single
Two unusual injuries of the growing ankle are the Tillaux fracture and the notorious triplane fracture. The TILLAUX fracture is an avulsion of a fragment of tibia by the anterior tibiofibular ligament; in the child or adolescent this fragment is the lateral pa of the epiphysis and the injury is therefore a Salter-Harri...
Orthopaedics
Management in Orthopedics
08cbce41-55ef-4a00-bf22-78830a82c0ff
Dextromethorphan differs from codeine in :
Its antitussive action can be blocked by naloxone
Depresses mucocilliary function of the airway mucosa
Addiction common
Causes no constipation
3d
single
null
Pharmacology
null
db4bb248-9068-4af5-bb89-706d40e640ea
Which of the following is a preventable cause of mental retardation –
Hypothyroidism
Down syndrome
Cerebral palsy
All of the above
0a
multi
null
Pediatrics
null
60b62bba-5e14-47d8-a656-43f70572bddf
Swimmer after coming out frm swimming pool presents with redness and mucopurulent discharge. There is no history of contact lens wear. On examination, no corneal involvement seen. Probable diagnosis is -
Acanthamoeba keratitis
Adul inclusion conjunctivitis
Vernal keratoconjunctivitis
Angular conjunctivitis
1b
single
This is case of Swimming pool conjunctivits/granuloma-Which is adult inclusion conjunctivitis caused by chlamydia trachomatis. Ref: Khurana 7th/e p.73 & 4th/e p.63,68
Ophthalmology
Conjunctiva
d7f0c5c5-4a01-4a24-99ab-c256dc1ff574
Normal paogram include all of the following EXCEPT: March 2013
Cervical dilatation in X-axis
Descent of head in Y-axis
Sigmoid shaped curve
Ale line followed 4 hours later by action line
0a
multi
Ans. A i.e. Cervical dilatation in X-axis Chas Paogram is: - Graphical representation of stages of labour; - Assessment of labour Cervicograph is: Graph showing relationship between cervical dilatation & labour
Gynaecology & Obstetrics
null
7c5bdcda-7526-45b8-a028-348116e9a778
Growth of C diphtheriae in Tellurite agar occurs in -
2-4 hours
4-8 hours
8-12 hours
1-2 days
3d
single
Ans. is 'd' i.e., 1-2 days * The usual media employed for cultivation of diphtheria bacillus are:-1) Loeffler's serum slope# It is used for rapid diagnosis as growth is shown within 4-8 hours.2) Tellurite blood agar (Tinsdale medium)# It acts as selective media, as tellurite inhibits growth of most other bacteria.# Gro...
Microbiology
Bacteria
3d1b7eeb-f64e-4900-9326-fc0aca1ea03b
Aspergillus causes all except
Bronchopulmonary allergy
Otomycosis
Dermatophytosis
Sinusitis
2c
multi
Dermatophytosis is caused by dermatophytes, which includes Microsporum, Trichophyton and Epidermophyton. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
Microbiology
mycology
fa9e9afc-1e44-4126-88b4-adddb29fd9ec
The most commonly employed method for superficial, minimally invasive nodular Basal cell carcinoma (BCC)?
Topical 5-fluorouracil
Cryosurgery
Electro-desiccation and curettage
Mohs micrographic surgery
2c
multi
All given options are used for Rx of BCC, but Electro-desiccation and curettage (ED&C) is most commonly employed method for superficial, minimally invasive nodular BCCs and low-risk tumors. Wide local excision is selected for invasive, ill-defined, and more aggressive sub types of tumors, or for cosmetic reasons. Mohs ...
Dental
Tumours of skin
81a25688-ed7f-4762-8360-a6ec0d2c5b64
Regarding antibiotics true are
No prophylaxis for clean contaminated surgery
No prophylaxis for gastric ulcer surgery
Prophylaxis for colorectal surgery
Local irrigation with antibiotic contraindicated when systemic antibiotics given
2c
multi
In clean contaminated surgeries (ex : gastric) , Prophylactic antibiotics are used In contaminated surgeries , lke colorectal surgeries prophylactic antibiotics are used
Surgery
General surgery
5e427130-ae8a-40be-9a27-2128a140362e
Used for averting smoking habit is -
Buspirone
Bupropion
Methadone
Venlafaxine
1b
single
Antismoking drugs are :- Vareniciline, Bupropion, Amfebutamone, Clonidine, Rimonabant, Topiramate, Nortryptyline, Glucose, Mecamylamine.
Psychiatry
null
a5f0414b-8148-4b52-b5e6-8d1656bcd31e
Which route of drug administration avoids first pass hepatic metabolism and is used with drug preparation that slowly releases drugs for periods as long as seven days ?
Topical
Transdermal
Sublingual
Oral
1b
single
null
Pharmacology
null
d375ff31-f1c9-4cf8-82a5-11b1b2b8b342
Tick transmits all except -
Relapsing fever
Tick typhus
Chagas disease
Viral encephalitis
2c
multi
Chaga's disease: It is transmitted by reduviid bugs.They are also called conenose bugs, they are of large size. Adults have wings. These bugs live exclusively on the blood of animals including man and transmit Trypanosoma cruzi, the causative agent of Chaga's disease. Ticks are ectoparasites of veebrate animals. They t...
Social & Preventive Medicine
Environment and health
b79b199d-e413-4431-b188-ef9af2ea6ba0
The dorsal pa of the ventral mesogastrium forms(2018)
A) Greater omentum
B) Lesser omentum
C) Faliciform ligament
D) Lineorenal ligament
1b
single
The lesser omentum is formed by two layers of peritoneum separated by a variable amount of connective tissue and fat. It is derived from the ventral mesogastrium. Ref:- Gray's anatomy, pg num:- 1101
Anatomy
Abdomen and pelvis
baf6a944-6c55-4f35-b679-a0169e94e93e
Antigaucomatous drug causing spasm of accommodation
Timolol
Pilocarpine
Dorazolamide
Latanoprost
1b
single
Ans. is 'b' i.e., Pilocarpine Ocular side effects of topical agents for POAG 13-blocker: Allergic blepheroconjunctivitis, corneal hyposthesia, blurred vision, dry eye, superficial punctate keratitis. Cholinomietics (pilocarpine): Blurred vision, miosis, accommodative spasm, browache. Sympathomimetics Non-selective (Dip...
Ophthalmology
null
205ac997-98c0-4e8c-88da-774b32d61158
Increasing number of services in rural areas is a pa of -
Intersectoral coordination
Equitable distribution
Appropriate technology
None
1b
multi
Ref: 25th Ed K.Park's Textbook Of Preventive and Social Medicine
Social & Preventive Medicine
Health care of community & international health
69e24527-9514-4c39-a33d-516d15f953d6
Placenta accreta is associated with all except :
Placenta pre
Uterine scar
Multipara
Uterine malformation
3d
multi
Risk factors for placenta accreta : Present placenta pre Previous H/o cesarean section Previous curettage Previous manual removal of placenta Previously treated Asherman syndrome Myomectomy Multiparity Advanced age Ref: Datta Obs 9e pg 394.
Anatomy
General obstetrics
e402ec83-4990-4d2a-874b-6fe7df5b3794
Recurrent dislocations are least commonly seen in:
Ankle
Hip
Shoulder
Patella
0a
single
Complete dislocation of Ankle is rare because the talus cannot be completely dislocated from the joint unless all ligaments are torn. Recurrent ankle instability following ligamentous injury may be seen, but such instability is not associated with frank dislocations (although subluxation of joint may be seen). Ref: Cam...
Surgery
null
3f35509b-27f5-4148-98c3-20cb2b76b230
Ectopic ACTH is commonly secreted by: September 2007
Small cell carcinoma of the lungs
Pancreatic carcinoma
Gall bladder malignancy
Medullary carcinoma of thyroid
0a
multi
Ans. A: Small cell carcinoma of the lungs Endogenous Cushing's syndrome results from some derangement of the body's own system of secreting coisol. Normally, ACTH is released from the pituitary gland when necessary to stimulate the release of coisol from the adrenal glands. In pituitary Cushing's, a benign pituitary ad...
Pathology
null
1f80034c-6659-4e04-84f3-71b1832eacbc
Pearl's index indicates:
Malnutrition
Population
Contraceptive failure
LBW
2c
single
Ans. is c, i.e. Contraceptive failureRef: Dutta Obs 6th/ed, p532-532Pearl index indicates the effectiveness of a contraceptive or is an index of contraception failure.* It is expressed in terms of "failure rate per hundred women - years of exposure (HWY)".* Failure rate per HWY=No.ofpatientsobservedxmonthsofuseTotalacc...
Gynaecology & Obstetrics
Contraceptives
e9fa45d0-55e7-4717-849d-b3c2215e3f09
drug transpo mechanisms include
passive transpo
lipid solubility
bioavavailability
distribution
0a
single
Ref-KDT 7/e p11-13 drugs are transpoed across the membrane by passive diffusion and filtration specialized transpo
Anatomy
General anatomy
4fcc2cd4-5af2-474e-8ce7-c8b408008d8c
Which can be used in pregnancy?
ACE inhibitors
Aldosterone
AT receptor antagonist
Propylthiouracil
3d
single
Propylthiouracil is used for hyperthyroidism during pregnancy. ACE inhibitors and Losartan should be avoided during pregnancy. ACE inhibitors can cause fetal renal tubular dysplasia when used in second and third trimester leading to oligohydramnios, fetal limb contractures, craniofacial deformities and hypoplastic lung...
Gynaecology & Obstetrics
null
e78a98c0-d55f-45d8-aab0-ebc6ada3098c
Frequency of renal involvement in HSP ?
20-40%
>80%
40-60%
10%
2c
single
Ans. is 'c' i.e., 40-60%The repoed incidence of renal involvement in HSP varies considerably between different studies.o This may be because of the different criteria used to describe the involvement & the variability of the length used to follow up.o In different studies incidence of pediatric renal involvement in HSP...
Pathology
null
d617e657-9622-4975-812e-77defe710235
A 23-year-old woman consults an obstetrician because of the onset of vaginal bleeding in what she considers to be the fifth month of pregnancy; however, examination reveals the uterus to be enlarged to the size of a 7-month pregnancy. Intravaginal ultrasound fails to detect a fetal heabeat and instead shows a "snowstor...
Preeclampsia.
Eclampsia.
Ectopic pregnancy.
Hydatidiform mole.
3d
single
Hydatidiform mole should be suspected when the uterus is enlarged beyond the expected size for the time of the pregnancy. HCG is markedly elevated in this gestational trophoblastic disease. H. mole on ultrasound shows a "snowstorm pattern ". Preeclampsia and eclampsia are forms of toxemia of pregnancy marked by severe ...
Pathology
Uterus
aa55e35b-ebce-46d2-a441-acaecdedbed4
The most common histologic type of thyroid cancer is
Medullary type
Follicular type
Papillary type
Anaplastic type
2c
single
Papillary carcinoma accounts for 80% of all thyroid malignancies in iodine-sufficient areas and is the predominant thyroid cancer in children and individuals exposed to external radiation." The incidence of primary malignant tumours of the thyroid gland Also, remember - Thyroid carcinoma is the most common malignancy o...
Anatomy
Endocrinology and breast
cb60b633-8947-4588-973f-c17711e92db3
Not true about right kidney is:
Right kidney is preferred over the left for transplantation
It is lower than the left kidney
Right renal vein is shorter than the left
Right kidney is related to the duodenum
0a
multi
Ans. (a) Right kidney is preferred over the left for transplantationLeft Kidney is preferred over the right kidney - Reasons:* Left kidney is chosen for its long renal vein which makes surgery easier.* Right kidney is related with duodenum.* Right kidney is lower than left kidney.
Surgery
Kidney & Ureturs
8c86621a-7f3e-4a0f-8891-de5cc6d47c79
All of the following are true regarding Down's Syndrome EXCEPT;
Only found in female
Simian crease
Growth retardation
Epicanthus with oblique palpebral fissure
0a
multi
Down's syndrome (Trisomy 21): Mental retardation Epicanthic folds and flat facial profile Simian's crease Umblical hernia Hypotonia Gap between first and second toe Congenital hea defects
Pathology
Specific Cytogenetic Disorders
469e9589-afe6-478b-84f9-d5878bb94c23
A 49 yr old male with a 35-pack-year history of smoking presents with a painless left scrotal mass. Examination revealed microscopic hematuria, absence of AFP and LDH. The most probable cause of the scrotal mass is:
Seminoma
Renal cell ca
Epididymitis
Ca lung
1b
single
Ans is 'b' i.e. Renal cell ca History of smoking suggests either Ca lung or Renal cell ca. Microscopic hematuria ors RCC. The painless left scrotal mass can be metastasis from RCC to the scrotum (which is rare but several cases have been repoed) or the mass could be varicocele. A secondary varicocele can be caused by c...
Surgery
null
57e8250d-e952-4778-b07e-d07f061965ad
Which personality disorder/s can be a pa of autistic sPectrum of disorders?
Schizoid
Schizotypical
Borderline
All the above
3d
multi
Ans. D. All the aboveFollowing personality disorders can be diagnosed later in life in patients with childhood autistic spectrum of disorders: Borderline, Obsessive compulsive, narcissitic, paranoid, schizotypical and, avoidant, personality.
Psychiatry
null
68b28744-7d23-413a-b6b5-0fc208a5942c
Principal cell in granuloma is
Lymphocyte
Histiocyte
Langhyans
Giant cell
1b
single
Ans. is 'b' i.e., Histiocyte Granuloma is characteristic ofgranulomatous inflammation. o The major cell of granuloma is epitheloid cell which is a modified tissue macrophage (histiocyte) that has been transformed into epithelium like cell.
Pathology
null
1202b747-45f3-45f8-9750-38c99a04265f
Which of the following is not seen in ARDS?
Hypoxemia
Hypercapnia
Pulmonary edema
Stiff lung
3d
single
Ref: Harrison's 18/e p2206, 17/e p1680,1681
Medicine
All India exam
30ca6298-f506-41e6-bdfc-b0f5abc23b21
Calcitonin is used in all of the following conditions, EXCEPT:
Hypervitaminosis D
Postmenopausal osteoporosis
Paget's disease
Fanconi syndrome
3d
multi
The ability of calcitonin to block bone resorption and lower serum calcium makes it a useful drug for the treatment of Paget's disease, hypercalcemia, and osteoporosis. Fanconi syndrome is a disease of the proximal renal tubules of the kidney in which glucose, amino acids, uric acid, phosphate and bicarbonate are passe...
Pharmacology
null
eaaeca46-414c-4a5c-95c6-6e1ea3208aa2
"Microsomia" is defined as
Bih weight below 90th percentile
Bih weight below 10th percentile
Bih weight below 20th percentile
Bih weight below 50th percentile
1b
single
A neonate whose weight falls between the 10th and <90th percentile for gestational age is considered as Appropriate for gestational age (AGA). If the weight falls below the 10th percentile, the neonate is classified as Small for gestational age (SGA) or microsomic. If the weight falls at or above the 90th percentile, t...
Pediatrics
New born infants
071ebea8-ec4f-4047-934a-02ccdb281362
1. Which does not pass through the aoic opening(2018)
A) Aoa
B) Vagus nerve
C) Azygos vein
D) Thoracic duct
1b
single
The aoic hiatus trans- mits the aoa, thoracic duct, lymphatic trunks from the lower posterior thoracic wall and, sometimes, the azygos and hemiazygos veins
Anatomy
Thorax
2dc50c5d-553a-4670-a73b-5e8b27260c55
Which of the following drug is given unsupervised as per National Health Programmes ?
Rifampicin
Ethambutol
Clofazimine
Dapsone
3d
single
Dapsone is not required to be given under supervision . Under NLEP, Rifampicin and Clofazimine are given under supervision for both Multibacillary and Paucibacillary Leprosy. Rifampicin is given 600 mg once a month under supervision. Clofazimine is given 300 mg once a month under supervision and 50 mg daily unsupervise...
Pharmacology
Mycobacterial Diseases (TB, Leprosy and MAC)
10aa819f-e0e4-4d96-b81e-4ff9643a6868
A young male was found to be HBsAg positivity and HBe Ag negative. His liver enzymes were normal. The next step in management of this young male should be:
Lamivudine therapy
Lamivudine plus IFN therapy
Sta IFN therapy
Serial monitoring
3d
multi
Answer is D (Serial Monitoring) Antiviral therapy (IFN, Lamuvidene, Adefovir, Entecovir) for chronic hepatitis B is indicated.* patients with active HBV replication. Negative HBe Ag and Normal levels of liver enzymes suggest that the patient is either in a non replicative phase of chronic hepatitis, or, is an inactive ...
Medicine
null
50b79f7d-a34e-4f1e-8340-1468ec0dc6be
Not a copper containing IUD ?
CuT-200
Nova -T
Multiload-250
LNG-20
3d
single
Ans. is `d i.e., LNG-20 LNG-20 is third generation IUD which does not contain cooper. Other three options are 2"d generation (copper containing) IUDs.
Social & Preventive Medicine
null
0e91f86f-f5c9-408c-b05c-0f6a4fd85535
About Hepatitis 'A' true is -
Causes mild illness in children
3% incidence of carrier state
10% transform into HCC
Veical transmission never seen
0a
multi
Type A hepatitis is a subacute disease of global distribution, affect mainly children and young adults. The disease is milder in children in whom many infections may be antiicteric. REF:ANATHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:541
Microbiology
Virology
e5d9f8dc-da45-4367-b806-97e5764a4e21
Causative organism of which STD has safety pin appearance:
LGV
Chancroid
Syphilis
Herpes genitalis
2c
single
Ans. is. 'c' i. e., Chancroid
Microbiology
null
ff60f448-03dc-42ec-a4a2-8e65dcb7c82e
Renin plays important role in -
Renovascular hypertension
Malignant hypertension
Coronary artery disease
Essential hypertension
0a
single
null
Medicine
null
3f78f687-67e9-4927-b0d5-2abac1a4e9a6
Most common cause of thyrotoxicosis in childhood ?
Toxic nodular goitre
Toxic adenoma
Graves disease
Thryotoxicosis factitia
2c
single
null
Pediatrics
null
18eb422c-db00-4b48-982f-e7943e058cfb
Acute hepatocellular failure in a patient of cirrhosis of liver is precipitated by -
Upper gastrointestinal bleeding
Large carbohydrate meal
Portal vein thrombosis
Intravenous albumin infusion
0a
single
null
Medicine
null
fbd9d6b0-cc48-4154-8d49-5a746fb4bef6
Which of the following type of glaucoma is treated by Argon Laser Trabeculoplasty?
Open angle glaucoma
Secondary glaucoma
Angle recession glaucoma
Angle closure glaucoma
0a
single
Laser trabeculoplasty is effective in the initial treatment of primary open-angle glaucoma. Application of laser (either argon or frequency-doubled Q-switched Nd:YAG) burns a goniolens to the trabecular meshwork facilitates aqueous out-flow by viue of its effects on the trabecular meshwork and Schlemm's canal or cellul...
Ophthalmology
null
e465aa8b-44b0-4aed-89b6-f1747e63adea
Hemoglobin is present in :
Hydrophilic pockets
Hydrophobic pockets
Pyrrole rings
Cationic ring
1b
single
Hemoglobin, a tetrameric protein of erythrocytes, transpos O2 to the tissues and returns CO2 and protons to the lungs. The heme in haemoglobin is surrounded by a hydrophobic pocket, which is necessary in order for it to bind oxygen reversibly without undergoing oxidation or other undesirable reactions. Ref: Kennelly P....
Biochemistry
null
bf8abbfb-db70-40b9-a94f-31a7986485cb
Peussis vaccine side effect
Local pain
Excessive cry
Fever
All of above
3d
multi
Ans. is 'd' i.e., All of the above Peussis vaccine Available as whole cell and acellular as DTPw and DTPa Primary immunisation at 6, 10, 14 weeks followed by booster dose 1'/2 year and 5 year. Whole cell causes more side effect than acellular Side effect-local pain, redness, fever, irritability, excessive cry because o...
Pediatrics
null
f34cb4e0-eb05-4899-83ad-33195f26b0ad
Which of the following drugs should not be used in the conduct of labour in a woman with rheumatic hea disease?
Methylergometrine
Carboprost
Synctocin
Misoprostol
0a
single
Methylergometrine (product containing ergot alkaloids) has a tendency to produce vaso-constriction. When given intravenously or intramuscularly (usually during the third stage of labour) cause sudden sustained contraction of the uterus. This uterine contraction causes a sudden addition of about 500 ml of blood into the...
Gynaecology & Obstetrics
null
d1d30bf2-1b45-430b-bd20-e512ef731b3b
Pus in burns form in -
2-3 Days
3-5 days
2-3 weeks
4 weeks
0a
single
Ans. is `a' i.e., 2-3 days Burn wound will almost inevitably be colonised by micro oraganism within 24-48 hrs.
Surgery
null