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135
bdd2e606-a2c5-4f54-b52d-522b43c70c2f
Which among the following doesn't enter human body skin?
Ancyclostoma
Strongyloides
Trichinella
Necator
2c
single
Trichinella REF: Jawetz, Melnick, & Adelberg's Medical Microbiology, 24T" edition chapter 46 Table 46-4 Indirect repeat in December 2011, See APPENDIX-74 for "DISEASES DUE TO HELMINTHS" "Trichinella infectes by ingestion of undercooked pork which contains encysted larvae in the straited muscle" Skin penetration is seen...
Microbiology
null
db16495c-6014-45df-a3b0-127ba5670c04
All of the following are TRUE about the middle ear, EXCEPT:
The joints between ossicles are synol
The chorda tympani nerve is related to the lateral wall
The facial nerve passes in a canal situated in the medial and anterior walls
The auditory tube connects the nasopharynx with the anterior wall
2c
multi
The facial nerve passes in a canal situated in the posterior and medial walls of the middle ear. It is not associated with the anterior wall.
ENT
null
f200d048-5e51-40af-aa78-2c6e66d5a944
All of the following malignancies present with osteoblastic secondaries, except
Multiple myeloma
Ca prostate
Ca breast
Carcinoid tumor
0a
multi
Multiple myeloma commonly presents as multiple osteolytic lesions in older patients and may simulate metastatic cacinoma. Carcinomas which present with osteoblastic secondaries are prostate carcinoma, breast carcinoma, seminoma, neurogenic tumors and carcinoid. Reference: Bone and Soft Tissue Pathology By Andrew L. Fol...
Medicine
null
7879f9fa-786e-4d78-80a5-61300c4c70cc
Which if the following is the ‘Yellow fever’ reference centre?
Haffkin’s institute, Mumbai
AIIMS, Delhi
NIN, Hyderabad
Central institute, kasauli
3d
single
null
Social & Preventive Medicine
null
e0f13fb1-30b4-4115-b85a-ae03628a7f56
Structure passing through the greater sciatic foramen are all of the following except `
Pyriformis
Superior gluteal nerve
Inferior gluteal nerve
Obturator internus tendon
3d
multi
Structure passing through lesser sciatic notch Tendon of obturator internus Pudendal nerve Nerve to obturator internus Internal pudendal aery
Anatomy
Muscles of Lower Limb
c17dd273-7970-4cd6-b5c4-033071700a1e
Which is the immediate danger to a patient with severe facial injuries
Bleeding
Associated fracture spine
Infection
Respiratory obstruction
3d
single
null
Surgery
null
68723611-3e74-457a-9745-5b6e5e0da0df
A young 8 years old boy with multiple, small, pin point, shiny, papular lesions on dorsal aspect of hand, forearms and his penis also. Diagnosis is:
Molluscum cantagiosum
Scabies
Lichen planus
Lichen nitidus
3d
multi
Ans. d Lichen nitidus (Ref: Mark Lebwohl 2nd/345)A young 8 years old boy with multiple, small, pin point, shiny, papular lesions on dorsal aspect of hand, forearms and his penis also. Diagnosis is Lichen nitidus.Grouped pinhead lesions on elbow. abdomen, penis and dorsum of hand in a child as shown in the picture is hi...
Skin
Lichen Planus & Lichenoid Dermatoses
e7c3f5c2-43e9-476a-9956-1d0475c789ae
Desmoplaskin is the target antigen in:
Pemphigus vulgaris.
Paraneoplastic pemphigus.
Drug induced pemphigus.
Pemphigus foliaceous.
1b
single
Paraneoplastic pemphigus is a severe variant of pemphigus, associated with an underlying neoplasm - most frequently non Hodgkin's lymphoma, chronic lymphocytic leukemia, thymoma, and castleman disease. Tumor antigens are hypothesized to evoke an immune response that leads to the development of an autoimmune response to...
Pathology
null
f417b9c2-5dfc-4b5a-b080-3864141eb89e
Highest slope of stress v/s strain curve seen in:
Ceramic
Enamel
Impression compound
Gold crown
3d
single
Elastic modulus of different materials
Dental
null
45de53e3-cfa6-46bf-bc43-580fcb56f2f1
The predominant isozyme of LDH in cardiac muscle is
LD-1
LD-2
LD-3
LD-5
0a
single
In myocardial infarction, total LDH activity is increased, while H4 iso-enzyme ( monomer of LDH ) is increased 5-10 times more. The magnitude of the peak value, as well as the area under the graph, will be roughly propoional to the size of the myocardial infarct. Ref: D M Vasudevan 7th edition Page no: 304
Biochemistry
miscellaneous
a99db976-4464-4d7a-bf49-80f28a66f395
What is the strength of shock given to below victim of cardiac arrest with shockable rhythm:
200 J asynchronous Shock
300 AC shock
200 Syn. Shock
300 J Syn. Shock
0a
single
It should be between 120-200 J asynchronized shock.
Anaesthesia
Cardiopulmonary Cerebral Resuscitation
e40b23e8-820b-46a1-8b41-b44a08bbca58
Unsaturated fatty acids are converted to:
Prostaglandins
Cholesterol
Cell membrane lipid
Saturated fatty acid
0a
single
A Harper, 26lh ed. p. 192 & 25th ed, p. 250
Biochemistry
Lipids
6cc0e9c0-808d-46e8-a745-3ec9973e73a7
"3 by 5" initiative in AIDS control programme is ?
Providing 3 million people treatment by end of 2005
Providing treatment to 3 out of 5 patients
Reducing incidence of AIDS by 3% by 2005
All of the above
0a
multi
Ans. is 'a' i.e., Providing 3 million people treatment by end of 2005 3 by 5 target On 1st December 2003, WHO and UNAIDS announced a detailed plan to reach the "3 by 5 target" of providing antiretroviral treatment (A) to three million people living with HIV/AIDS in the developing countries by the end of 2005. Ultimate ...
Social & Preventive Medicine
null
d38cc733-3035-4957-b5bc-a8b724c4757c
Which of the following congenital malformation is seen in a child of a mother who is on treatment with oral anticoagulants -
Craniofacial malformations
Renal agenesis
Long bone defects
All
0a
multi
Ans. is 'a' i.e., Craniofacial malformations o "Administration of warfarin (Oral anticoagulants) during pregnancy causes syndrome characterized by 1. Nasal hypoplasia (Craniofacial malformation) 2. Stippled epiphyseal calcifications that resemble chondrodysplasia punctata."
Pediatrics
null
f241c6fc-4d96-4bab-973f-5f5a18fc1772
All of the following are advantages of LMA Except
More reliable than face mask
Prevent aspiration
Alternative to endotracheal intubation
Does not require laryngoscope & visualization
1b
multi
LMA is intermediate between the face mask and endotracheal intubation in terms of reliability, invasiveness, and facilitation of gas exchange (face mask has minimum and endotracheal intubation has maximum)LMA does not prevent aspiration - should not be used in full stomach patientsLMA can be used as an alternative to e...
Anaesthesia
All India exam
80c5b5b8-430b-423d-aee5-8ff8954c8feb
Which one of the following is an absolute contraindication to the use of thrombolytic agent in the setting of an acute anterior wall myocardial infarction-
History of CVA with hemiparesis one month ago
Diabetic retinopathy
Patient's age more than 70 years
Patients is on warfarin for A.F with INR ration 1:8
0a
multi
Ref: R. Alagappan Manual for Medicine 4th Edition pg no:188-189 Contraindications for Thrombolytic Therapy Absolute contraindications: Active bleeding Defective haemostasis Recent major trauma Surgical procedures < 10 days Invasive procedures < 10 days Neurosurgical procedure < 2 months GI/genito-urinary bleeding < 6 m...
Medicine
C.V.S
e87162c5-e747-4ffc-ac95-44a97da7fbe8
Calcaneum is associated most commonly with which # -
# rib
# vertebrae
# skull
# fibula
1b
single
Most common mechanism of injury is fall from height, often from a ladder, onto one or both heels. The calcaneum is driven up against the talus and is split or crushed. About one fifth of these patients suffer associated injuries of the spine, pelvis or hip.
Orthopaedics
null
aeba1468-2548-49f5-aba5-3f0a98afedd5
A farmer presented with a black mole on the check. It increased in size, more than 6mm with sharply defined borders with central black lesion, what could be the diagnosis?
Acral lentigo melanoma
Superficial spreading melanoma
Lentigo maligna melanoma
Nodular melanoma
1b
single
Superficial spreading melanoma It is the M/C type of melanoma It is the M/C type which occurs in a patient with pre existing mole. R/F for superficial spreading melanoma- Increasing age Melanoma in situ Many melanocytic nevi Multiple >5 atypical nevi Strong family H/O melanoma
Dental
NEET Jan 2020
b3e71cfc-3dce-4058-bdf0-3699eef53091
Which of the following types of pancreatitis has the best prognosis
Alcoholic pancreatitis
Gall stone pancreatitis
Post operative pancreatitis
Idiopathic pancreatitis
1b
multi
.Ranson's prognostic criteria On admission:--* Old age >55 years * Blood sugar >200 mg% * TC >16,000/mm3 * Serum LDH > 350 IU/L * Serum SGOT > 250 IU/L In 48 hrs: * Base deficit > 4 mEq/L * Serum calcium < 8 mEq/L * Haematocrit : altered by 10% * Aerial O2 (PO2) < 60 mm Hg * Extravascular space fluid loss: > 6 * Blood ...
Surgery
G.I.T
4b825897-f36f-4e85-9e06-b3a78c3d0874
Which method is used to locate a known gene locus?
FISH
CGH
Chromosome painting
RT-PCR
0a
single
Ans. A. FISH(Ref: Robbins 9/e page 177)Robbins 9th edition gives the following descriptionFISH uses DNA probes that recognize sequences specific to particular chromosomal regions.MethodRequires growing cellsDetects deletion and duplicationDetects balanced structural rearrangementsDetects uniparental disomyLower limits ...
Biochemistry
Molecular Biology Techniques
e701ba86-1690-4b2f-8f39-cb1c36d0d27e
Most common nosocomial infection is
Respiratory tract infection
Gastrointestinal tract infection
Urinary tract infection
Throat infection
2c
single
null
Social & Preventive Medicine
null
46c49dcf-7330-499b-a7f8-a61bd7387ab9
A child is posted for operative repair of exostrophy of bladder with renal failure. Which anesthetic should be preferred?
Pancuronium
Vecuronium
Ataracurium
Rocuronium
1b
single
C i.e. Ataracurium In pediatric patients the choice of non depolarizing muscle relaxant depends on side effects and duration of action. The method of excretion of atracurium and cisatracurium (Hofman elimination and ester hydrolysis) makes these relaxants paicularly useful in newborns and children with liver or renal d...
Anaesthesia
null
9d3a73c5-86bc-49e7-bd69-0b947cc2fb81
Which of the following is the best predictor for future risk of cardiovascular events?
hs CRP
Interleukin 6
Lipoprotein 'a'
Homocysteine
0a
single
CRP is made in the liver in response to excess triglyceride storage. Elevated CRP levels>3mg/l using a high sensitive assay is associated with an increased risk of CHD. Another useful marker is lipoprotein associated phospholipase A2(LpPLA2). It is made by macrophages in response to excess cholesterol storage. Its leve...
Medicine
null
889dac82-4096-41ab-a2ce-df5427c536f7
Enzyme use in ELISA -
Alkaline phosphatase
Acid phosphatase
Glucosidase
Glycosyl transferase
0a
single
(A) (Alkaline Phosphate) (64- Harper 29th) (730 U. Satyanarayana 4th)ELlSAs use antibodies covalently linked to a "reporter enzyme" such as alkaline phosphatase or horseradish peroxidase whose products are readily detected, generally by the absorbance of light or by flourescence (64- Harper 24th)* ELISA is based on the...
Biochemistry
Enzymes
69a3c09c-cadd-46b4-839c-9d0260f8ff45
Which of the following structures is not at immediate risk of erosion by cholesteatoma?
Long process of incus
Fallopian canal containing facial nerve
Horizontal semicircular canal
Basal plate of stapes
3d
multi
Cholesteatoma has the propey to destroy the bone by viue of the enzymes released by it.Structures immediately at the risk of erosion are:-The long process of the incusFallopian canal containing facial nerveHorizontal/lateral semicircular canalRef: PL Dhingra, Diseases of Ear, Nose & Throat, 7th edition, pg no. 73 - 74
ENT
Ear
b3f76834-eb74-4cb2-9fdb-325466816c6a
High-risk breast cancer female investigation of choice is?
MRI
USG
Mammography
Clinical examination
0a
single
– To differentiate scar from recurrence. – To image breasts of women with implants. – To evaluate the management of axilla and recurrent disease. It is useful in screening females with the high-risk group. T1 and T2 weighted images are taken. Irregular mass with speculations, changes in skin and nipple, lymphoedema ar...
Surgery
null
2912c137-7e86-4858-ba1b-21493f38259e
Radiosensitisers are all Except
Metronidazole
Nimorazole
Cisplatin
Amifostine
3d
multi
Radiosensitisers are agents that increase the lethal effects of radiation when given during (or sholy prior) to its delivery. There are three clinically used radiosensitisers - hypoxic cell sensitisers, hypoxic cell cytotoxics and the halogenated pyrimidines - that increase the sensitivity of tumour cells with minimal ...
Radiology
Radiotherapy
882e0a18-0253-40b7-97e6-910f9d391df7
Open reduction is indicated in
clavicle
both bone forearm in children
lateral condyle humerus
supra condyle humerus
2c
multi
Ans. is 'c' i.e. lateral condyle humerus lateral condyle humerusis commonly displaced and is treated by OR & IF with K wires*Treatment of clavicle -Conservative figure of 8 bandage *Treatment of both bones fore arm in children -In children these fractures are often undisplaced or minimally displaced therefore managed c...
Orthopaedics
Humerus Fractures
7cc542ba-d23b-47d8-b852-e0c4836909a9
A neonate delivered at 38 weeks of gestation with a bih weight of 2.2 kg develops intolerance to feed /abdominal distension on second day. Physical examination is unremarkable. Sepsis screen is negative. PCV is observed to be 72%. Which of the following represents the best management option?
Hydration with IV Fluids
Paial Exchange Transfusion
Presumptive treatment for sepsis
Medical Management for intestinal obstruction
1b
multi
Neonate mentioned in the case is suffering from neonatal polycythemia. Long term complications of neonatal polycythemia can be prevented by treating symptomatic children with paial exchange transfusion of blood. Ref: Neurology in Clinical Practice: The neurological disorders - Page 1108; Blueprints pediatrics By Bradle...
Pediatrics
null
ed12d22c-51b8-4b31-94f4-6144fcb80784
22-year-old lady, with a history of epilepsy is undergoing the pre-anaesthetic review. The use of which inhalational agent is contraindicated in this patient?
Halothane
Enflurane
Sevoflurane
Isoflurane
1b
single
Enflurane can precipitate generalized tonic clonic seizure in epileptics. It is however safer than halothane, causes less myocardiac depression and less hypotension.
Anaesthesia
null
8c936a70-da6e-488b-9d3d-7812760221e4
Commonest side effect of cryotherapy for carcinoma cervix in situ :
Hemorrhage
Persistent watery discharge
Cervical stenosis
Ulceration
1b
single
Persistent watery discharge
Gynaecology & Obstetrics
null
a5663718-8c8b-46f4-ab4d-4a0357c911f9
Most commonly associated Fungus with orbital cellulitis in patients with Diabetic Ketoacidosis is
Candida
Mucor
Aspergillus
Histoplasma
1b
single
(B) MucorRhino - Orbital mucormycosis:Mucormycosis is a very rare opportunistic infection caused by fungi of the family Mucoraceae, which typically affects patients with diabetic ketoacidosis or immunosuppression. This aggressive and often fatal infection.Specific infections - rhinocerebral mucormycosis:Fungal infectio...
Ophthalmology
Systemic Disease
18ffb899-fa33-4730-865c-879a983ea4bb
All of the following are ocular symptom seen in Herpes ophthalmicus, EXCEPT:
Oculomotor nerve involvement
Disciform keratitis
Anterior uveitis
Nummular keratitis
0a
multi
Herpes Zoster ophthalmicus involves ophthalmic branch of the trigeminal nerve. Herpes Zoster affecting the second and third division of the trigeminal nerve, and other cranial nerves is likely uncommon. When it occurs it may produce lesions in the mouth, ear, pharynx or larynx. Signs of Herpes Ophthalmicus are: Acute v...
Ophthalmology
null
4aa117c4-d626-48fc-bf2b-7363e3ec2b84
True about pilocytic astrocytoma all except aEUR'
Long survival
Total surgical resection possible
Can involve posterior fossa
Median age at presentation is more than 80 years
3d
multi
Median age at presentation is more than 80 years Astrocytomas Histologically astrocytomas are classified into ? a) Protoplasmic or fibrillary b) Gemistocytic (enlarged cells distended with hyaline and eosinophilic material) c) Pilocytic (consists of enlarged bipolar cells) d) Mixed astrocytoma or oligodendroglioma Astr...
Pathology
null
2423d12b-9755-428d-a814-fb05f9053f2e
Radiofemoral delay is characteristic of ____________
Patent ductus aeriosis
Coarctation of aoa
Aoic dissection
Takayasu's disease
1b
single
In coarctation of aoa there will be radiofemoral delay. Ref : Ghai essential of pediatrics, eighth edition, p.no:432
Pediatrics
C.V.S
b5a916dd-644c-4a92-b2fb-48fab094b59f
Dried semen stains on clothes identified by -
Spectrometry
UV rays
Infrared rays
LASER
1b
single
Ref: the synopsis of forensic medicine &toxicology-Dr.K.S. Narayana reddy 28th edition pg no:236 proof of semen: the only absolute prrof of semen is the finding of atl;east one unbroken spermatozoon,or electrophoretic LDH isoenzyme detection of sperms. in the absence of spermatozoa, a stain which gives characteristic f...
Forensic Medicine
Special topics
d330c43b-1bc5-49ea-a40e-ae3942af1324
Superior quadrantanopia is seen in lesion of:
Parietal lobe
Temporal lobe
Frontal lobe
Occipital lobe
1b
single
Ans: b (Temporal lobe) Ref: Khurana, 4th ed,p. 290Superior quadrantanopia is seen in temporal lobe lesions and inferior quadrantanopia is seen in parietal lobe lesions.Lesions of the visual pathway* Optic nerve- u/1 complete loss of vision* Optic chiasma(Central lesion)-bitemporal hemianopia* Lateral chiasma-binasal he...
Ophthalmology
Neuro-Ophthalmology
e440f955-65d2-4480-9235-095bb3e2f7ef
Drug of choice for reversal of is neuromuscular blockade by vacuronium-
Edrophonium
Neostigmine
Sugamadex
Pyridostigmine
2c
single
Ans: C. Sugamadex(Ref: KDT 7h/e p. 355; Basic of Anasthesia e book - 157)Sugamadex provides faster reversal of vacuronium - induced neuromuscular blockade compared with neostigmine.A modified gamma-cyclodextrin with high affinity towards vacuronium & recuronium.
Anaesthesia
null
d387c2b9-3e1c-4d75-9155-9424475cb31d
A 23-year-old woman has noticed that she develops a skin rash if she spends prolonged periods outdoors. She has a malar skin rash on physical examination. Laboratory studies include a positive ANA test result with a titer of 1 :1024 and a "rim" pattern. An anti-double-stranded DNA test result also is positive. The hemo...
Basophilia
Eosinophilia
Monocytosis
Neutrophilia
2c
single
An autoimmune disease, most likely systemic lupus erythematosus (SLE) in this patient, can be accompanied by monocytosis. Cytopenias also can occur in SLE because of autoantibodies against blood elements, a form of type II hypersensitivity. Basophilia occurs infrequently, but also can be seen in chronic myelogenous leu...
Pathology
Blood
f59aa50f-14c1-436a-bb13-aa7f7b9c1176
Basal Metabolic Rate depends most closely on:
Lean body mass
Body mass index
Obesity
Body surface area
0a
single
A i.e. Lean body mass
Physiology
null
f7580221-2e65-4aa1-962c-11b438f46977
Teratozoospermia refers to?
Absence of semen
Absence of sperm
All dead sperms in ejaculate
Morphologically defective sperms
3d
multi
Ans. (d) Morphologically defective spermsRef: Harrison 18thed ch-346, Smith Urology 17thed p.691, style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif"> publications/2010Z9789241547789_eng.pdf
Pathology
Male Genital Tract
0802ce59-2705-4780-81ec-aa243531ffd8
Tamoxifene -
SSRI
SERM
SNRI
DNRI
1b
single
Ans. is 'b' i.e., SERM o Tamoxifen is a selective estrogen receptor modulator (SERM).SELECTIVE ESTROGEN RECEPTOR MODULATION (SERMs)1. Tamoxifen citrate# It is a nonsteroidal compound# It has both estrogen antagonist as well as partial agonist activity -Tamoxifen (selective estrogen receptor modulator)o Sites on which i...
Pharmacology
Sex-Hormone
07f8e6b4-8dbe-45d5-84f1-0ae4a5bbaa16
A myocardial infarct specimen is showing early granulation tissue. According to this change when has the infarct occurred?
Less than 1 hour
Within 24 hours
Within 1 week
Within 1 month
2c
single
Following a myocardial infarction, early formation of fibrovascular granulation tissue at margins occur in 7-10 days.Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 558; Essentials of Rubin's Pathology By Emanuel Rubin, 5th Edition, Pages 277-8
Pathology
null
4f03a63b-760d-49f8-9f35-79a43401768d
A man came to the casualty with some skin lesions after exposure to the sun. He is allergic to sunlight. Solar uicaria is characterized by:
Stinging
Erythema
Wheal formation
Loss of sensation
2c
multi
Uncommon sunlight-induced whealing confined to exposed body sites. Eruption occurs within minutes of exposure and resolves in a few hours. Very disabling and sometimes life threatening. Action spectrum is UVB, UVA, and visible light or any combination thereof. Most commonly UVA. Is an immediate type I hypersensitivity ...
Skin
null
ac8f8e85-4d2d-4803-8310-0f51df7869e1
A double aoic arch is due to persistent ?
Right 4th arch
Right 6th arch
Left 4th arch
Left 6th arch
0a
single
Double aoic arch is most common vascular ring, caused by abnormal persistence of the distal segment of the RIGHT of 4th aoic arch. On lateral, arches are posterior to esophagus and anterior to trachea. Symptoms (of tracheal compression or difficulty swallowing) may begin at bih. Aoic arches: Aoic arches are sho vessels...
Anatomy
null
3b0c9b7a-14cb-4f17-81e1-6f0c34d5d847
"Intranuclear inclusions" in oligodendrocytes are seen in
Creutzfeldt Jacob disease
Polio
Japanese encephalitis
Progressive multiple encephalopathy
3d
single
progressive multifocal leukoencephalopathy, JC virus-infected oligodendroglia display 2 distinct patterns of intranuclear viral inclusions: full inclusions in which progeny virions are present throughout enlarged nuclei and dot-shaped inclusions in which virions are clustered in subnuclear domains termed "promyelocytic...
Physiology
All India exam
a48b93f9-5413-4b1c-b1cd-5b9a95e643cc
PSGN (post-streptococcal GN) associated with -
Subepithelial deposits
Nephritis along with acute Renal failure
Low complement levels
HTN and protenuria
0a
single
Electron microscopy shows deposited immune complexes arrayed as subendothelial, intramembranous, or, most often, subepithelial "humps" nestled against the GBM robbins book of pathology. 9th edition. Page 529
Pathology
Urinary tract
eeec4c59-0438-4504-9807-ee2c9a169cac
Essential atrophy of the choroid is due to inborn error of metabolism of which amino acid?
Cystine
Cysteine
Arginine
Ornithine
3d
single
Ans.D.) Ornithine. Ornithine aminotransferase deficiency (also known as gyrate atrophy of the choroid and retina) is an inborn error of ornithine metabolism, caused by decreased activity of the enzyme ornithine aminotransferase. Biochemically, it can be detected by elevated levels of ornithine in the blood. Clinically,...
Ophthalmology
null
e1dcc08d-7949-418c-a152-b7de6690e688
A 9-year-old girl is diagnosed with acute rheumatic fever. Instead of recovering as expected, her condition worsens and she dies. Which of the following is the most likely cause of death?
Central nervous system involvement
Endocarditis
Myocarditis
Streptococcal sepsis
2c
single
The most common cause of death that occurs during acute rheumatic fever is cardiac failure secondary to myocarditis.
Pathology
Rheumatic Fever
28d5a333-b1ea-473b-a3db-a6ff723505ee
Minimal change glomerulopathy may be seen ' association with all of the following except,
Hepatitis B
HIV
Drug-induced interstitial nephritis
Hodgkin's disease
0a
multi
Secondary MCD wherein the extraglomerular disease process evokes, directly or indirectly, the characteristic changes in permselectivity and morphology. In this circumstance the morphology is similar, if not identical, to primary or 'idiopathic' MCD. Moreover, it is possible, even likely, that similar or identical patho...
Medicine
Kidney
dddea16a-ee02-410e-b535-70c693da17bc
Reactive ahritis is usually caused by:
Shigella flexneri
Shigella boydii
Shigella shiga
Shigella dysenteriae
0a
multi
Organisms that have been associated with Reiter Ahritis include the following: C trachomatis (L2b serotype) Ureaplasma urealyticum Neisseria gonorrhoeae Shigella flexneri Salmonella enterica serovars Typhimurium Mycoplasma pneumoniae Mycobacterium tuberculosis Yersinia enterocolitica and pseudotuberculosis Campylobacte...
Medicine
Rheumatoid Ahritis
9c1d9264-1693-4442-b081-b40062ba0446
Puerperal sepsis is due to spread of Infection along which route :
Direct extension
Aerial
Venous
Lymphatics
0a
single
Direct extension
Gynaecology & Obstetrics
null
fd84a0fd-aae5-43a1-a150-9c42bb28176f
Total body water constitute what percentage of Body Weight
80%
60%
33%
25%
1b
single
null
Physiology
null
d40c1c5d-1869-4b75-be74-996492449c86
Which of the following characterizes mallampati class 3
Only hard palate visible
Both hard palate and soft palate visible
Hard palate ,soft palate, uvula and faucial pillars visible
None
1b
multi
Both hard and soft palate should be seen in grade 3.
Anaesthesia
null
e103b6c2-d4ec-4b6c-817b-00fb3a20660a
Functions of limbic system :
Emotion
Memory
Higher function
All
3d
multi
A i.e. Emotion B i.e., Memory C i.e., Higher function Limbic System It is the entire neuronal circuit that controls emotional behaviour & motivational drives and a term that originally was used to describe bordering structures around basal region of cerebrum. Functions of hypothalamus Posterior Hypothalmus Pa of hypoth...
Physiology
null
2c747006-5f50-4c42-9f86-40be9313c139
Variconazole is not effective against-
Aspergillosis
Mucormycosis
Candida albicans
Candida tropicalis
1b
single
Ans. is 'b' i.e., Mucormycosis o Amongst azole, only posaconazole is active against mucormycosis. o Voriconazole is used for i) Invasive aspergillosis (voriconazole is the DOC) Candida infection iii) Pseudollescheria boydii (Scedosporium apiospermum) infection iv) Fusarium infection
Pharmacology
null
677163f4-75d5-4046-acfd-4fbfff2a0e61
The third heart sound is due to:
Closure of AV valve
Closure of aortic valve
Mid diastolic flow in the ventricle
Atrial contraction
2c
single
“A  soft, low-pitched  third sound  is heard about one third of the way through diastole in many normal young individuals.”
Physiology
null
3936f165-39ad-46e4-bddb-51f766e8233a
All of the following are branches of cerebral pa of the internal carotid aery, EXCEPT:
Ophthalmic aery
Anterior cerebral aery
Posterior communicating aery
Meningeal aery
3d
multi
Meningeal aery is a branch of cavernous pa of Internal carotid aery.Must know:The internal carotid aery begins at the superior border of the thyroid cailage as one of the terminal branches of common carotid aery.Its course is divided into four pas: Pas of ICABranches(A) Cervical pasNo branches(B) Petrous paCaroticotymp...
Anatomy
null
163d1e0a-5417-4f13-ad9d-9ec6f0a03493
Fundoscopic features of papilledema include all the following except -
Ill- defined disc margin
Deep physiological cup
Absent venous pulsation
Bending of blood vessels
1b
multi
Physiological cup is filled and obliterated (not becomes deep). Ophthalmoscopic signs of papilloedema Blurring of disc margin (first sign) Venous :- Engorgment, congestion, loss of pulsation Hyperemia of the disc with capillary dilatation. Filling of physiological cup with gradual obliteration of physiological cup. ...
Ophthalmology
null
f4953b19-6a47-4be8-923c-231af902d2f4
All of the following statements are true regarding poliovirus, except:
It is transmitted by feco-oral route
Asymptomatic infections are common in children
There is a single serotype causing infection
Live attenuated vaccine produces herd immunity
2c
multi
Ans. is 'c' i.e., There is a single serotype causing infection There are 3 types of poliovirus which are associated with infection.
Microbiology
Virology
0c0d912b-4a73-42b5-8d35-51863efea0e5
Consider the following disorder- Sydenham's chorea Migraine Mania Obsessive compulsive disorder Valproic acid is used in ehich of the above disorders?
1 and 3 only
2 and 4 only
1, 2, and 3
2, 3, and 4
2c
multi
Treatment. There is no specific treatment for Sydenham's chorea and symptoms usually resolve themselves in approximately 3 to 6 months. Bed rest, sedatives and medication to control movements may be prescribed. Penicillin prophylaxis may also be prescribed to avoid fuher streptococcal infection. valproic acid can also ...
Medicine
Miscellaneous
98fcac00-a064-4f9a-9593-f40e65cafbb6
The fibers from the contralateral nasal hemiretina project to the following layers of the lateral geniculate nucleus
Layers 2,3 & 5.
Layers 1,2 & 6.
Layers 1,4 & 6.
Layers 4,5 &6.
2c
single
Look at figure 12-17 trace the nasal field of one eye it goes to layers 1,4,6 on contralateral side. Ref: Ganong&;s review of medical physiology;23rd edition; pg:194
Physiology
Nervous system
df9ff390-f527-4853-8e2f-be7ead12b145
Delta waves are seen in:
Deep sleep
REM sleep
Awake state
Stage II nREM sleep
0a
single
REM sleep is characterized by b waves, the waves actually of ale wakefulness. Hence, REM sleep is also called "paradoxical sleep". Awake state with eyes closed - a waves; with eyes open - b waves. NREM sleep: stage 1 shows periodic sho bursts of a waves.
Physiology
Higher Functions
07a17f18-d7f5-4c83-b9d9-ff22608def1e
Eyelid drooping in/are seen in:
Damage to edinger-westphal nucleus
Damage to motor pa of facial nerve
Damage to sympathetic nerve supply
Damage to lacrimal nerve
2c
single
Ans. Damage to sympathetic nerve supply
Ophthalmology
null
ffa4063d-d470-4236-8997-57762a4e507c
Van Nuys prognostic indicator for DCIS does not include which of the following parameter?
DCIS size
Age of the patient
Type of DCIS
Excision margin
2c
single
Ans. (c) Type of DCIS(Ref: Sterenberg diagnostic surgical pathology 5th ed p 312)The Van Nuys Prognostic Index (VNPI) classifies patients with DCIS to guide decisions on the best treatment option. The index uses patient age, tumour size, tumour growth patterns (histological grade) and the amount of healthy tissue surro...
Pathology
Breast
ab4813ce-696a-44e4-acbe-d2501c6facc4
Wernicke's encephalopathy, during refeeding syndrome, can be precipitated in deficiency of which of the following vitamin: September 2011
Riboflavin
Pyridoxine
Thiamin
Vitamin C
2c
single
Ans. C: Thiamin In patients who are thiamin deficient, Wernicke's encephalopathy can be precipitated by refeeding with carbohydrates This is prevented by administering thiamin before staing nutritional suppo
Medicine
null
c9659d60-8b30-443d-8d34-588be23e3be1
Condition that can be diagnosed on laparoscopy?
Endometriosis
DUB
Carcinoma cervix
Pyometra
0a
single
Ans. a (Endometriosis). (Ref. Williams, Obstertrics, 21st ed., 930)ENDOMETRIOSISDefinition# Occurrence of ectopic endometrial tissues outside the true cavity of uterus.Etiology# Samson's implantation theory attributed to reflux of menstrual endometrium through tubes.# Coelomic metaplasia theory.# Metastatic theory.# Hi...
Gynaecology & Obstetrics
Gynaecological Diagnosis
7f4cbefd-b73c-40bc-830f-ed18ac50eb73
The Point of distinction between paial mole to complete mole is
Paial mole show trophoblastic proliferation with absent villi
Typical of paial mole is cellular atypia
Paial mole is more prone to tumor malignancy
Paial mole is triploid
3d
single
Ref: Shaw&;s Textbook of Gynecology; 16th edition; Chapter 22; Gestational Trophoblastic Diseases
Gynaecology & Obstetrics
General obstetrics
b7332987-ba7a-406e-aeb8-0f31c24c829a
The late features of kernicterus include all except
Hypotonia
Sensorineural Hearing loss
Choreoathetosis
Upward Gaze palsy
0a
multi
Hypotonia is not a feature of kernicterus . Initial findings associated with kernicterus may vary from case to case, but often include lack of energy (lethargy) or drowsiness, poor feeding habits, fever, a shrill high-pitched cry, and/or absence of ceain reflexes (e.g., Moro reflex, etc.). Affected infants may eventual...
Pediatrics
New born infants
dcfe5b2b-5c0c-49d9-b2f0-32e73a00f66b
Drug of choice for gonococcal as well as non gonococcal urethritis is
Clindamycin
Cefepime
Metronidazole
Azithromycin
3d
single
Gonococcal Infections For gonococcal urethritis: DOC is ceftriaxone For non gonococcal urethritis: DOC is AZITHROMYCIN It is used in combination with ceftriaxone in both gonococcal & non gonococcal urethritis AZITHROMYCIN (Single dose is enough)
Pharmacology
Protein Synthesis Inhibitors
39b39ad0-5854-48a5-b1e1-97477f9e3592
Hardy Weinberg law indicates all except:
States that genotype frequencies in a population remain constant or are in equilibrium from generation to generation unless specific disturbing influences are introduced
Hardy Weinberg law states that population is static
Factors influencing gene pool include mutation, natural selection, population movements(assertive mating), public health measures
Natural selection is a process where harmful genes are not eliminated from the gene pool and genes favorable to individual are not passed onto offspring .
3d
multi
Ans. (d) Natural selection is a process where harmful genes are not eliminated from the gene pool and genes favorable to individual are not passed onto offspring.Acc to Hardy Weinberg law genes are passed on to the offsprings in a gene pool.
Social & Preventive Medicine
Miscellaneous
df87620b-8512-4b3f-9f75-f44c1bd2358e
River blindness is caused by :
Drinking river water without boiling.
Oncocerca volvulus
Toxoplasma canis
Glaucoma
1b
single
Ans. is 'b' i.e. Onchocerca volvulus Onchocerca volvulus is transmitted by Simulium damnosum, a black fly* that breeds in areas of rapidly flowing streams thus the term 'river blindness9T/t by Ivermectin*
Ophthalmology
Ocular Manifestations
dd1d828b-86fd-49fb-9aa2-8c999f424ff1
All are indications for stopping effending ATT drug permanently except
Gout
Autoimmune thrombocytopenia
Optic neuritis
Hepatitis
3d
multi
Ans. is 'd' i.e., Hepatitis For patients with symptomatic hepatitis and those with marked (five to six fold) elevations in serum levels of aspaate aminotransferase, treatment should be immediately stopped and drugs reintroduced one at a time after liver function has returned to normal. Indications for stopping the A.T....
Medicine
null
e6adec1a-b297-4f58-8331-26e6e740657a
True regarding 10-0 sutures is/are?
Thicker than 1-0 sutures
Synthetic sutures
Diameter is 0.9 mm
Stronger than 1-0
1b
multi
Answer- B. Synthetic suturesThe larger the size ascribed to the suture, the smaller the diameter be.10-0 sutures- 0.2 (0.020-0.029)
Surgery
null
71fe6450-b19b-4251-849f-f887098b4f83
For Ca Anal canal t/t of choice is -
Surgery
Surgery + Radiotherapy
Chemoradiation
Chemotherapy
2c
single
Nigro regimen refers to combined chemotherapy and radiotherapy for primary treatment of malignant tumors of the anal canal. In the 1970s, Nigro pioneered preoperative combination chemoradiation therapy to convert unrespectable cases to respective cases. There was no surgical pathological evidence of tumor found in thre...
Surgery
null
8968be99-663d-4a55-ab17-ca0a65fdcffa
All are involved in iron metabolism except:
Hepcidin
Ferroportin
Transthyretin
Ceruloplasmin
2c
multi
Ans. C. TransthyretinHepcidin is the regulator of iron homeostasis. Ferroprotin is their on exporter protein into circulation from intestinal cells. Ceruloplasmin has ferroxidase which convert Fe2+ to Fe3+ so it can serve the purpose of hephaestin in iron metabolism. Transthyretin is a transport protein for Thyroxine a...
Biochemistry
Nutrition & Digestion
e6045e48-e903-4bdf-b4ff-87bfa63d1f84
All are a type of audio-visual aids except
Television
Cinema
Flannel graph
Side-tape combination
2c
multi
Flannel graph: Audiovisual aids: No health education can be effective without audiovisual aids. Auditory aids: radio, cassette tape-recorder, microphone, amplifier, earphone, public address system, disks Visual aids: Not requiring projection: Chalk-bored, leaflets, posters , chas, flannel graphs, exhibits, models, spec...
Social & Preventive Medicine
Health education & planning
0e04eccf-8744-45fc-a1a9-9aaf0c8142b0
All are true regarding satellite DNA EXCEPT?
Repeated DNA sequences in tandem
Clustered around centromere
Clustered around telomeres
Transcriptionally active
3d
multi
Ans. is 'd' i.e., Transcriptionally active Repetitive sequences in DNAis also called (satellite DNA)These consist of 5-500 base pair lengths repeated many times.These are often clustered in centromeres (central protein of chromosomes where sister chromatids join each other) and telomeres (repeated sequence at the end o...
Biochemistry
null
84201266-7b6f-4cc1-9d8a-45a91a05e0ee
What happens to corneal endothelium after injury?
Slowly regenerates
Regenerates rapidly
Never regenerates
Forms a scar
2c
single
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 95 - 96)The cell density of endothelium is around 3000 cells/mm2 in young adults, which decreases with the advancing ageCorneal endothelium does not regenerate but adjacent cells slide to fill in a damaged area.Endothelium studied by specular microscop...
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
57566de4-ac91-49b0-afcb-07962c4c96d8
Drug not causing exanthematous skin eruption
Phenytoin
Hydrocoisone
Ampicillin
Phenylbutazone
1b
single
Drugs causing exanthematous eruptions are penicillin, sulfonamides, anticonvulsants, anti tubercular , allopurinol, nevirapine, phenylbutazone. Hydrocoisone is a coicosteroid is used for the treatment of severe drug reactions but will not induce exanthem
Dental
Fungal infections, Scabies, Pediculosis
5200758a-2759-4a2f-a78a-3e0fcb44117c
Fulminant Amoebic meningoencephalitis caused by-
Acanthamoeba
N.fowleri
E.Histolytica
E. Coli
1b
single
null
Microbiology
null
129b4d5c-6ea3-42e8-8bb6-d5c1c9dc94fd
Cochlear function in fetus develops between
12 to 15 weeks
18 to 20 weeks
22 to 25 weeks
30 to 34 weeks
2c
single
Cochlear function develops between 22 and 25 weeks, and its maturation continues for six months after delivery.Reference: William&;s Obstetrics; 24th edition; Chapter 7; Embryogenesis and Fetal Morphological Development
Gynaecology & Obstetrics
General obstetrics
bc502b79-e6b0-4707-a1e6-2a0c86b0c7cd
Which of the following is not one of the phases of Implantation of Embryo?
Epithelialization
Apposition
Adhesion
Invasion
0a
single
Implantation of Embryo can be divided into three phases: Apposition--initial contact of the blastocyst to the uterine wall Adhesion--increased physical contact between the blastocyst and decidua; and Invasion--penetration and invasion of syncytiotrophoblast and cytotrophoblast into decidua , inner third of the myometri...
Gynaecology & Obstetrics
Physiological Changes of Pregnancy
1ee64c00-c786-48ec-94c5-0a893eb21277
Which is false about pulmonary embolism?
Chest pain is most common symptom
Arises from leg vein
More the survival time, more the chance for recovery
Neck veins may be distended
0a
multi
Dysponea is the commonest symptom and tachyponea is the commonest sign. The most common presenting symptom of pulmonary embolism is dyspnea. Dyspnea, pleuritic chest pain, and tachypnea were present in 97% of patients with pulmonary embolism. PE most commonly results from deep vein thrombosis. Clinical signs include lo...
Medicine
null
c727ee48-6d80-4a14-9174-3d86709a8878
Dysmorphic RBC with ARF is seen in?
Glomerular disease
Renal carcinoma
Proximal tubule disease
Distal tubule disease
0a
single
Ans. (a) Glomerular disease(Ref: Henry's 22nd/ 457- 458)Dysmorphic RBCs with ARF is seen in Glomerular disease, while isomorphic RBCs are seen in non-glomerular bleeds;
Pathology
Kidney
91ecf3aa-c03c-4f6c-9310-a2bd147dbf0b
Cadaveric spasm develops
Less than 2 hours of death
6 hours of death
Instantaneous with death
Same as rigor mortis
2c
single
(Instantaneous with death): (150 31st/edition; 3.18- Parikh's 6th/e)CADAVERIC SPASM or instantaneous rigor or Cataleptic rigidityCharacterized by stiffening of the muscles immediately after death without being preceded by the stage of primary relaxationThe conditions necessary for its development are1. Somatic death mu...
Forensic Medicine
Death and Investigations
21f3935c-f400-4b55-9093-4ff882067488
LEAST common presentation of fibroid uterus is?
Infeility
Amenorrhoea
Pelvic mass
Menorrhagia
1b
single
Symptoms of fibroid uterus Menorrhagia, polymenorrhoea, metrorrhagia, continuous or postmenopausal bleeding Infeility, recurrent aboions Pain Pressure symptoms Abdominal lump Vaginal discharge
Gynaecology & Obstetrics
Fibroids
be1a4605-b3c3-4496-9945-a928bebdc760
All of the following is given for the treatment for Pityriasis versicoler Except:
Ketoconazole
Griseofulvin
Clotrimazole
Selenium sulphate
1b
multi
B i.e. Griseofulvin
Skin
null
bba31bb4-86df-4e13-a76c-0e9676689507
Which of the following anti–arrythmic drug decreases the action potential duration in purkinje fibers ?
Quinidine
Flecainide
Amiodarone
Lignocaine
3d
single
null
Pharmacology
null
c77dc040-ab9b-4bc0-b1bc-4e936fc98fef
Symmetrical persistent enlargement of the parotid gland is seen in:
Sjogren syndrome.
Cylindroma.
Mickuliz disease.
All of the above.
2c
multi
null
Pathology
null
6c282b0d-1eb1-4307-8435-e6b7c1ef3223
All of the following drugs are indicated in the treatment of bipolar disorder except?
Carbamazepine
Vigabatrin
Sodium valproate
Lamotrigine
1b
multi
BIPOLAR DISORDER Drug of choice for bipolar disorder is lithium. Alternatives to lithium are some antiepileptics (carbamazepine, valproate, lamotrigine, topiramate), antipsychotics (olanzapine, aripiprazole, haloperidol) and benzodiazepines. Carbamazepine and valproate are useful in manic depressive psychosis (bipolar ...
Pharmacology
Psychiatric Illness
485d7992-c847-4869-90d0-72a6e983009b
Fear is
A primary emotion acquires soon after birth
A primary emotion acquired in utero
A primary emotion acquires several years after birth
Not a primary emotion
0a
single
null
Dental
null
1ecb8806-abcf-400a-9b40-d8f8374e6413
Cultivable (in vitro) hepatitis virus is?
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
0a
single
Ans. is 'a' i.e., Hepatitis A "HAV can be cultivated reproducibly in vitro" - Harrison Remember . HAV is the only cultivable hepatitis virus
Microbiology
null
1e8213e7-a3a8-4fdf-9c90-2c8c867b9c17
In all of the following diseases chronic carriers are found except:
Measles
Typhoid
Hepatitis B
Gonorrhoea
0a
multi
Ans. is 'a' i.e. Measles In measles the only source of infection is a case of measles. Carriers are not known to occur.For more see Q no. 31 of Dec 1998.
Social & Preventive Medicine
Measles
218d3b5c-95e3-4188-9995-d29e87a71ecb
Most common cause of hydronephrosis is children
PUJ obstruction
Ureterocele
Posterior urethral valve
Ectopic ureter
0a
single
In children Most common cause of hydrophosis is Pelvi Ureteric junction obstruction.
Pediatrics
null
be5bf260-cec9-422f-a12c-cb3a04fd4a97
The following are direct signs of Lung collapse seen on the Chest X-ray except:
Mediastinal shift
Displacement of the fissure
Crowding of the vessels
Loss of aeration
0a
multi
Ans. A. Mediastinal shift. (Ref. Sutton radiology 7th ed. 161)Direct signs of lung collapse includeIndirect signs are:i) opacity of the affected lobe(s)ii) crowding of the vessels and bronchi within the collapsed area:iii) displacement or bowing of the fissures.i) compensatory hyperinflation of the normal lung or lobes...
Radiology
Respiratory System
a819d1ee-14d4-4562-a5df-e90f5b4020f1
A patient presents with melaena normal renal function, hypeension and mononeuritis multiplex. The most probable diagnosis is:
Classical polyaeritis nodosa
Microscopic polyangiitis
Henoch-Schonlein purpura
Buerger's disease
0a
multi
Answer is A (Classic PAN) : Amongst the options provided, mononeuritis multiplex is a feature of classical PAN and microscopic polyangitis. Presence of hypeension (infrequent in microscopic polyangitis) and normal renal function (infrequent in microscopic polyangitis) leads us to a diagnosis of classical polyaeritis no...
Medicine
null
198b1301-60ff-4613-9b2f-f004ed729a9b
A wave in JVP is due to -
Atrial systole
Atrial diastole
Ventricular systale
Ventricular diastole
0a
single
Ans. is 'a' i.e., Atrial systole JUGULAR VENOUS PULSE.a waveIt is the positive presystolic wave produced by right atrial contraction.x descenta wave is followed by the negative systolic wave the x' descent.The x descent is produced due to atrial relaxation.The atrial relaxation is produced as a result of ventricular co...
Physiology
Heart, Circulation, and Blood
8549885d-e978-4e44-a291-bcf640bb83dd
Area falling under 2 S.D. curve would be around -
66%
95%
57%
99%
1b
multi
Ref: Parks 23rd edition pg 848 The several measures of variation or dispersion of which the following are widely known : RangeThe mean or Average detion The standard detion . Ref:Parks 23rd edition pg 849. 1SD : confidence limit = 68% 2SD : confidence limit = 95% 3SD : confidence limit = 99.7%
Social & Preventive Medicine
Biostatistics
740725c8-9bee-4ded-aee1-170a163d7818
Hypoxic pulmonary vasoconstriction due to
Irreversible pulmonary vasocontriction hypoxia
Reversible pulmonary vasoconstriction due to hypoxia
Direct blood to poorly ventilated areas
Occurs hours after pulmonary vasoconstriction
1b
single
Hypoxic pulmonary vasoconstriction (HPV), also known as the Euler-Liljestrand mechanism, is a physiological phenomenon in which small pulmonary aeries constrict in the presence of alveolar hypoxia (low oxygen levels). Ref Harrison20th edition pg 2334
Medicine
C.N.S