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135
92506fff-10a3-401f-b5ae-b61a43c02c63
True-regarding DNA-replication:
Semi conservative
Sister Chromatids are formed.
Follow base pair rule
All of the above
3d
multi
All of the above
Biochemistry
null
ce403c7e-3974-43db-975b-4c65e7c018bc
Nipple confusion means?
Baby fed with a bottle finding it difficult and confusing to suckle at breast
Baby not able to suckle with bottle
Baby not able to feed with spoon
Baby not able to feed with paladin
0a
single
Ans. (a) Baby fed with a bottle finding it difficult and confusing to suckle at breastRef: OP Ghai 8th ed./153* A problem that may beset a bottlefed baby in which it forgets how to nurse on mother' nipple* Breastfeeding requires far more vigorous mouth and tongue motions and greater muscle coordination than bottlefeedi...
Pediatrics
Newborn Infant - Parent-Infant Bonding
083d69ba-8d0b-453c-a921-0f5eb17fc21c
Which of the following releases single wavelength of energy?
QTH
PAC
LED
Argon lasers
3d
single
null
Dental
null
cde502eb-c45b-48ae-ae52-2557bd0c44ac
Enzyme Transketolase requires ?
FAD
TPP
PLP
FMN
1b
single
Transketolase reactions require thiamine pyrophosphate (TPP).Coenzyme can be classified according to the group whose transfer they facilitate.a) For transfer groups other than hydrogen :- Sugar phosphate, CoA-SH, thiamine pyrophosphate (TPP), Pyridoxal phosphate, Folate, Biotin.b) For transfer of hydrogen : - NAD+, NAD...
Biochemistry
null
2202281e-136d-4e12-9213-75e16160dda2
What is seen earliest in USG?
Yolk sac
Fetal hea
Chorion
Placenta
0a
single
Yolk sac is the first anatomic structure seen within gestational sac. By TVS, it can be seen as early as 5.5week By TAS, it is seen by 7 weeks. Ref:Datta Obs 9e pg 601.
Anatomy
General obstetrics
a486fa29-9373-4089-b386-29fc81ae001a
Tennis Racquet cells
Rhabdomyoma
Rhabdomyosarcoma
Histiocytoma
Eosinophilic granuloma
1b
single
Rhabdomyosarcoma An adjectival description for a relatively elongated cell, lesion, structure or radiological density that is globose at one end and elongated at the other, alike to the device used in game of tennis. Tennis racquet cell: A tennis-racquet-shaped variant of rhabdomyoblast seen in sarcoma botryoides, a fo...
Surgery
null
e88f3bf5-68a3-4edc-9246-91182c12a061
Hidebound disease is:
DLE.
Scleroderma.
Acrodermatitis enteropathica.
None.
1b
multi
Systemic Sclerosis: Scleroderma, dermatosclerosis, hidebound disease.
Pathology
null
1bbd28c0-3f7b-454d-bb10-a0ca6d10bb22
Patient with head injuries with rapidly increasing intracranial tension without hematoma, the drug of choice for initial management would be:
Furosemide
Steroids
20% Mannitol
Glycine
2c
single
Mannitol is an osmotic diuretic. It is used for Increased intracranial or intraocular tension (acute congestive glaucoma, head injury, stroke, etc.): by osmotic action, it encourages the movement of water from brain parenchyma, CSF and aqueous humor; The dose is 1-1.5 g/kg is infused over 1 hour as 20% solution to tran...
Pharmacology
Kidney
6793137d-ceb8-425d-a05b-4ab34fc440f7
Which is derived from thoracolumbar fascia -
Medial arcuate ligament
Lateral arcuate ligament
Lacunar ligament
Cruciate ligament
1b
single
Ans. is 'b' i.e., Lateral arcuate ligament o Thoracolumbar fascia covers the deep muscles of back of the trunk, o It is composed of three fascial layers -i) Anterior layer# It is the thinnest layer# Medially it is attached to transverse process of lumbar vertebrae.# Laterally it fuses with fascia transversalis and apon...
Anatomy
Upper Extremity
d3136d26-80ab-4897-b66c-e6f7aea9c927
A patient with carcinoma lower 1/3 of oesophagus, receives chemo Radiotherapy and dysphagia shows complete response. What is the next step in management?
Reassure
Follow with CT scan every 6 months
Esophagectomy
EUS to look for residual disease
2c
multi
- Clinical trials and meta-analyses have shown that a C + surgery regimen could significantly improve the survival of locally advanced esophageal carcinoma patients compared to surgery alone - Endoscopic biopsy, endoscopic ultrasonography, MRI (at various sequences) and PET-CT all had shocomings for evaluating cCR and ...
Surgery
Esophagus
fb9e1456-bf45-4e00-9ce5-93ada545bbbf
Dennie-Morgan fold is seen in -
Dermotomyositis
SLE
Psoriasis vulgaris
Atopic dermatitis
3d
single
dennie morgan fold-accentuated grooves or lines below the lower eyelid margins. seen in atopic dermatitis. Ref Harrison20th edition pg 2534
Dental
Dermatitis
dd6bb095-deba-46a7-b86a-2bc943c7eec0
Stereotactic radiosurgery is used in which of the following conditions?
Metastatic brain tumors
Aeriovenous malformations
Trigeminal neuralgia
All of the above
3d
multi
STEREOTACTIC RADIOSURGERY - SRS is a non-surgical radiation therapy used to treat functional abnormalities & small tumors of brain - Deliver precisely-targeted concentrated dose of radiation in fewer high-dose treatments to a defined volume in the brain Common uses of Stereotactic Radiosurgery (BAT) - Brain tumor(Benig...
Surgery
CNS Tumors
701710e5-217f-42c3-8bb4-2494f74a4094
In MVP, you would expect the ejection click to be more accentuated and the murmur to move closer the first hea sound in a patient
With marked anxiety
Who is pregnant
Who is passive leg lifting in the supine position
On a beta blocker
0a
single
Anxiety, with an increase in hea rate or decreasing venous return to the hea (standing), causes the click and murmur to occur earlier in systole (closer to S1). Lying down, squatting, sustained hand grip exercise, or passive leg lifting in the supine position increase venous return and cause the click and murmur to occ...
Medicine
C.V.S
4ded324d-e5ef-4cb1-9eb8-9c8a5e142517
Typhoid in first week of illness is best diagnosed by:-
Serum widal test
Stool culture
Urine test
Blood culture
3d
single
Laboratory diagnosis of typhoid : 'BASU' mnemonic Test of diagnosis Time of diagnosis Remarks Blood culture 1st week Mainstay of diagnosis Antibodies (widal test) 2nd week Moderate sensitivity & specificity Stool culture 3rd week Useful for carries Urine test 4th week Useful for carries
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
9693492a-6454-4150-bcfc-9db9cf012eb4
Prostaglandin causing renal vasodilation:
PGD2
PGE2
PGF2
All
1b
multi
B i.e. PGE2 Blood vesselsPlateletsBronchiKidneyUterusPGE2VasodilationVariable effectDilatationVasodilatationRenin releaseContractionSoftening of cervix ContractionSoftening of cervixPFF2aVasodilation-Constriction-PGI2VasodilationAntiaggregatoryDilatationVasodilationRenin release?TXA2VasoconstrictionAggregationConstrict...
Physiology
null
5dbc98d9-6f6e-44cb-b9d1-9b8d98d2a174
Cerberus is associated with development of:
Head
Lung
Liver
None of the above
0a
multi
The cells in the hypoblast (endoderm) at the cephalic margin of the disc form the anterior visceral endoderm, which expresses head forming genes, including OTX2, LIM1, and HESX1 and the secreted factor Cerberus. Ref: Langman's embryology 11th edition Chapter 5.
Anatomy
null
aee71dd5-817e-4133-8440-904a72076ed8
In which orthodontic movement utmost control is required
Intrusion
Extrusion
Tipping
Rotation
0a
single
null
Dental
null
d2a518ce-7947-4f64-848e-2b71d057e8c7
Acute onset of cough, stridor and respiratory distress in the absence of fever is suggestive of:
Foreign body
Acute asthma
Aspiration Pneumonia
Primary complex
0a
single
Ans. A. Foreign bodyImmediate symptoms of foreign body inhalation include choking, coughing, increasing respiratory distress or difficulty in speaking.
Pediatrics
Respiratory System
bce6f8d3-50ae-4f4f-8b28-6c31bae6fc82
Erythropoietin in kidney is secreted by
Juxtaglomerular cells
PCT cells
Interstitial cells in peritubular capillaries
Capillaries of glomerulus
2c
single
Interstitial cells in paritubular capillaries releoses erythroportin in responce to hypoxia.
Physiology
null
ec795fd6-9a36-4fe9-9858-3aae7c9d46e2
What is the reason for Thyroid Storm after Total Thyroidectomy?
Due to Rough handling during Surgery.
Due to Inadequate preparation of patient
Recurrent Laryngeal Nerve Injury
Parathyroid Damage
1b
single
Ans. (b) Due to Inadequate Preparation of PatientRef: Surgery Sixer 3rd Edition 229* It is a condition of hyperthyroidism accompanied by fever, central nervous system agitation or depression, cardiovascular dysfunction that may be precipitated by infection, surgery or trauma and occasionally by amiodarone administratio...
Surgery
Thyroid Gland
1247c2ee-17b5-4b4e-86ad-0bfd30a73e40
True statement about tetracycline is
Inhibiting protein synthesis by binding to 50s ribosomes in susceptible microorganisms
Tetracyclines have chelating property
Tetracyclines have anabolic activity
Tetracyclines are infrequently responsible for superinfection
1b
multi
null
Pharmacology
null
231512b9-f1e3-4514-8ae3-7bd8d8960725
'Alien limb' is characteristically seen in:
Coico basal degeneration
Diffuse Lewy body disease
Fronto temporal dementia
Alzheimer's disease
0a
multi
Coicobasal degeneration (CBD) is a slowly progressive dementing illness associated with severe gliosis and neuronal loss in both the coex and basal ganglia. CBD with unilateral onset presents with rigidity, dystonia, and apraxia of one arm and hand, sometimes called the alien limb when it begins to exhibit unintended m...
Medicine
null
fc473f40-f128-4b31-9049-0747643a6cca
Baby 20 year old female complains of sudden onset palpitation and apprehension. She is sweating for last 10 minutes and fears of impending death. Diagnosis is -
Hysteria
Generalized anxiety disorder
Cystic fibrosis
Panic attack
3d
single
The information in this question are: - 1) Sudden (abrupt) onset, 2) Palpitation, 3) Apprehension, 4) Sweating, 5) Sense of impending doom, 6) Symptoms lasts for few minutes (10 minutes). These are the features of panic disorder.
Psychiatry
null
ea815bbf-747d-434a-a009-da13cf6d2d39
Which of the following is not caused by over expression of a trinucleotide repeat?
Alzheimer's disease
Fragile X
Huntington disease
Spinocerebellar ataxia Type 2
0a
single
Ans: a (Alzheimer's disease) Ref: Ganong, 22nd ed, p. 215Alzheimer's disease is not caused by over expression of a trinucleotide repeat. The rest 3 options are examples of trinucleotide repeat diseases where as Alzheimer's is primarly a degenerative disease (Basal ganglia) resulting in movement disorder.Some examples o...
Pathology
Genetics
0a71bf5b-67ae-4403-91d7-acf91ec138cd
Irreversible dementia is caused due to:
Subarachnoid hemorrhage
Wilson's disease
Normal pressure hydrocephalus (NPH)
Vascular dementia
3d
single
Vascular dementia is a cause of progressive dementia due to impaired blood supply to the brain.
Pathology
null
87b19c10-d3b3-4357-af21-51019d1f77a8
A 64-year-old man, who is a chronic alcoholic, presents with fever, chills and increasing shoness of breath. The patient appears in acute respiratory distress and complains of pleuritic chest pain. Physical examination shows crackles and decreased breath sounds over both lung fields. The patient exhibits tachypnea, wit...
Legionella pneumophila
Klebsiella pneumoniae
Mycoplasma pneumoniae
Streptococcus pneumoniae
1b
multi
Klebsiella pneumoniae is the most frequent cause of gram-negative bacterial pneumonia. It commonly afflicts debilitated and malnourished people, paicularly chronic alcoholics. Thick, mucoid (often blood-tinged) sputum is characteristic because the organism produces an abundant viscid capsular polysac-charide, which the...
Pathology
Infectious Lung Disease: Pneumonia
1475b3bc-988b-42ab-8262-e10ba681ed1b
The protein synthesis site of the cell body of neurons
Nissl bodies
Dendrites
Axon
All
0a
multi
The nissl bodies are the protein synthesis site in a neuron They are equivalent to rough endoplasmic reticulum Ref:Guyton and Hall textbook of medical physiology 12th edition ,page number 676
Anatomy
General anatomy
8e5e9d48-5bee-417e-9aa9-e00f34b51fdd
Bounderies of anatomical snuff box are all except
APL
EPL
EPB
ECU
3d
multi
Ans. is 'd' i.e., ECU Anatomical Snuffbox Triangular depression on the dorsal and radial aspect of the hand become visible when thumb is fully extended. Boundaries Medial/Posterior - Tendon of the extensor pollicis longus. Lateral/Anterior - Tendon of the extensor pollicis brevis and abductor pollicis longus. Roof Skin...
Anatomy
null
596275d2-892d-4b34-8ad2-0a611d279f36
Endemicity of a disease means:
Occurs clearly in excess of normal expectancy
Is constantly present in a population
Exhibits seasonal pattern
Is prevalent among animals
1b
single
Endemic Is the constant presence of a disease agent in a defined geographical area ; refers to 'usual or expected frequency' of a disease in a population. For instance, common cold is endemic because somebody always has one. Endemic diseases in India are : Measles, mumps, rubella, chicken pox, peussis, TB, HIV, Cancers...
Social & Preventive Medicine
Time Distribution, Epidemics
41f65994-4b88-4d54-a3c3-667259ef92ad
Sulfasalzine is used in: March 2011
Gout
Irritable bowel disease
Ulcerative colitis
Idiopathic osteoahritis
2c
single
Ans. C: Ulcerative Colitis The mainstay of drug therapy for mild and moderate ulcerative colitis is sulfasalazine and other aminosalicylic acid (ASA) compounds and coicosteroids Sulfasalazine It is a sulfa drug, a derivative of mesalazine (also called 5-aminosalicylic acid, or 5-ASA) Sulfasalazine is used in the treatm...
Pharmacology
null
46cf0c97-f1ae-4f50-a0c9-b6a486530507
True about sentinel surveillance is: March 2011
Continuous oversight of activities
Supplements routine notification system
Beneficial for malaria surveillance
Keeps a check over health in border regions
1b
multi
Ans. B: Supplements routine notification Sentinel surveillance helps in supplementing notified cases (those given through routine surveillance system- passive and active) Sentinel surveillance It is the collection and analysis of data by designated institutions selected for their geographic location, medical specialty,...
Social & Preventive Medicine
null
f0e85597-d8a0-4915-aa30-f8a8c38dbe52
Paget's disease of the nipple is
Superficial manifestation of underlying breast Ca
Galactocele
Eczema
All of the above
0a
multi
Paget's disease of the nipple is superficial manifestation of an intraductal breast carcinoma. The malignancy spreads within the duct up to the skin of the nipple and down into the substance of the breast. It mimics eczema of nipple and areola. In Paget's disease, there is a hard nodule just underneath the areola, whic...
Surgery
Urology
3e5a2e35-214d-4fdb-9bee-5ca14bcc6f3e
One of the following disorders is due to maternal disomy
Prader Willi syndrome
Angelman syndrome
Hydatidi form mole
Klinefelter syndrome
0a
single
ref Robbins 9/e p173 Matetnal disomy is associated with disorders like prader Willi syndrome, angelman syndrome.
Anatomy
General anatomy
fe50e1c0-663e-4606-80dc-55f071d07db2
Continuous murmur is seen in all the following except:
Aoic sinus of valsalva rupture
Coarctation of Aoa
AV malformations
Peripheral pulmonary stenosis
3d
multi
Answer is D (Peripheral Pulmonary Stenosis) The 'num:11r of pglmonary stenosis is harsh systolic ejection murmur typically preceded by a systolic ejection sound. It is not a continuous murmur. Continuous murmurs result from continuous flow between a high pressure and low pressure area that persists through the end of s...
Medicine
null
969aa1a2-101d-4a98-a773-03a391ef7ae8
Looser's zones is seen in – a) Osteoporosis b) Hyperparathyrodismc) Osteomalacia d) Renal osteodystrophye) Paget's disease
bcde
abd
abcd
acde
0a
single
Looser's zone or pseudofracture is pathognomonic for osteomalacia, However, it may occur rarely also in Paget's disease, Fibrous dysplasia, Hyperparathyroidism, Renal osteodystrophy, Hyperphosphatasia, and osteogenesis imperfecta.
Radiology
null
6ee6d0d8-3b54-41a3-aaa5-1945be7ee2d1
Acquired blue blindness is a feature of
Disease of optic nerve
Disease of macula
Increased sclerosis of the crystalline lens
All of the above
2c
multi
Acquired Colour Blindness Acquired blue colour defect (blue blindness) : It may occur in old age due to increased sclerosis of the crystalline lens. It is owing to the physical absorption of the blue rays by the increased a.ambercoloured pigment in the nucleus. Ref:- A K KHURANA; pg num:-305
Ophthalmology
Neuro-ophthalmology
ef9e727f-25db-49f1-9246-0f4434d1dd01
Most common cause for meningitis in adults: September 2009
H.Influenzae
N.meningitidis
Staph.aureus
Streptococcus pneumoniae
3d
single
Ans. D: Streptococcus pneumoniae Streptococcus pneumoniae is the most common cause of meningitis in adults of age over twenty years, accounting for nearly half of the cases. N. meningitidis accounts for nearly 25% of the cases. Staph.aureus and coagulase negative staphylococci are impoant causes of meningitis that occu...
Medicine
null
6322cfb5-4266-40ac-8ee4-b1ff12a8c200
False statement about post-dural puncture headache (PDPH):
Breach of dura
Onset of headache is usually 12-72 hours following procedure
Commonly occipito - frontal in location
Headache is relieved in sitting standing position
3d
multi
Post Dural puncture Headache Pathophysiology - CSF leak - ICP |es - Traction on nerve fibres originating from piamater Site - Occipital > Frontal > Retrorbital Duration - 7-10 days Pathognomic sign - Change in posture aggravates headache Predisposing conditions - Dura cutting needle (spinal needle)* Most commonly seen ...
Anaesthesia
FMGE 2018
4f972d3b-144b-415c-9e27-f7e06138de1f
A 7 years old child from Bihar is having hypo pigmented anaesthetic patch on his face. What is the most probable diagnosis?
Intermediate leprosy
Pityriasis alba
Nevus anemicus
Nevus achromicus
0a
single
Recurrent scaly hypopigmented macule on the face of a child - P. alba Recurrent scaly hypopigmented macule on the face of an adult - P. versicolor Resident of the endemic zone with an anaesthetic patch over face - Indeterminate leprosy
Dental
null
7a39b7b8-5fa7-4726-a532-babf8482b908
Mycobacterium tuberculosis was discoverd by ?
Louis pasteur
Robe koch
Lister
Jener
1b
single
Ans. is 'b' i.e., Robe koch Scientist Associated with Fracastorius Proposed a contagium vivuin (cause of infectious disease) Von Plenciz Suggested that each disease is caused by a separate agent Augustino Bassi Earliest discovery of pathogenic microorganism Davaine and Pollender Observed anthrax bacilli in blood of ani...
Microbiology
null
3051f2b1-bd67-4737-9954-30239b4ed4ab
Which of the following is used for abdominal pregnancy
Studiford criteria
Speigelberg criteria
Rubins criteria
Rotterdam criteria
0a
single
Studdiford criteria : To diagnose the abdominal pregnancy Both the tubes and ovaries are normal without any recent injuries Absence of uteroperitoneal fistula Presence of pregnancy related exclusively to the peritoneal surface and young enough to eliminate the possibility of secondary implantation following the primary...
Gynaecology & Obstetrics
General obstetrics
ec24da99-03f2-4731-8aad-22539e5f9b0c
Commonest stomach tumour which bleeds ?
Adenocarcinoma
Squamous carcinoma
Lei om yosarcoma
Fibrosarcoma
2c
single
Ans. is 'c' i.e. Leiomyosarcoma
Surgery
null
41701f03-d960-4046-ae0b-57032e343298
Farber&;s disease is due to the deficiency of
Ceraminidase
Sphingomyelinase
Glucocerebrosisase
Neuraminidase
0a
single
Farber disease (also known as Farber&;s lipogranulomatosis, ceramidase deficiency, "Fibrocytic dysmucopolysaccharidosis," and "Lipogranulomatosis" is an extremely rare autosomal recessive lysosomal storage disease marked by a deficiency in the enzyme ceramidase that causes an accumulation of fatty material sphingolipid...
Biochemistry
miscellaneous
69dddd4c-3e5d-48ec-b35e-86109c52c989
Which of the following configuration is used in designing an RPD with Kennedy — Class II edentulous arch?
Bilateral
Tripod
Quadrilateral
Unilateral
1b
single
null
Dental
null
9c2a1890-7766-4beb-b113-5658719dbe8b
A specific test for gout is -
Raised serum uric acid level
Raised uric acid in synovial fluid of joint
Raised urea level
Raised urease enzyme level
1b
single
Demonstration of intracellular monosodium urate crystals (MSU) in synovial fluid from affected joint is diagnostic of gout.
Orthopaedics
null
08831171-0348-4306-9e41-3095409611e6
In severe cases of anterior uveitis whole circle of pupil gets adhered to lens capsule resulting in:
Occlusio pupillae
Seclusio pupillae
Festooned pupil
Mydriatic pupil
1b
single
Seclusio pupillae/ring synaechiae/annular synaechiae is seen in severe iritis or recurrent uveitis, in which whole circle of pupillary margin becomes tied down to the lens capsule. It can lead to secondary angle closure glaucoma. Note: Occlusio pupillae/blocked pupil occurs when exudation in uveitis is extensive. They ...
Ophthalmology
null
b259b28b-4d42-41fa-9a39-97d7b8b7dcb4
In RMNCH+A Staegy, what is plus ?
Adolescent health
Reproductive health
DPT Vaccination
Newborn health
0a
single
Ans. is 'a' i.e., Adolescent health The RMNCH+A strategy is based on provision of comprehensive care through the five pillars, or thematic areas, of reproductive, maternal, neonatal, child, and adolescent health, and is guided by central tenets of equity, universal care, entitlement, and accountability. The "plus" with...
Social & Preventive Medicine
null
9c681901-587b-446e-82a4-31d8f3e60ee6
Infection/ inflammation of all of the following causes enlarged superficial inguinal lymph nodes except:
Isthmus of uterine tube
Inferior pa of anal canal
Big toe
Penile urethra
3d
multi
D. i.e. Penile urethra Penile (spongy) urethra of male mostly drain to deep inguinal lymph nodes
Anatomy
null
8625ed41-d265-497a-8128-5d0f1837aae2
Peripheral resistance is decreased in which type of shock -a) Hypovolemic shockb) Neurogenic shockc) Septic shockd) Cardiogenic shock
a
c
ac
bc
3d
single
Septic shock has already been described → in hyperdynamic stage there is vasodilation and  ↓ TPR. Neurogenic shock Neurogenic shock occurs when there is Neurological injury as occur in head trauma or high cervical cord injury or cephalad migration of spinal anaesthesia. Interruption of sympathetic vasomotor input occu...
Pathology
null
51a7145f-56e0-430d-9525-30470ed2e655
Antifungal used as cancer chemotherapeutic agent is :
Flucytosine
Nystatin
Voriconazole
Terbinafine
0a
single
null
Pharmacology
null
59101bd7-d67f-485f-8e90-6477f59694b9
A 50-year-old woman presents with lower back pain of 3 weeks in duration. Radiologic studies reveal several discrete lytic lesions in the lumbar back and pelvis. Laboratory studies show elevated serum levels of alkaline phosphatase. Serum calcium, serum protein, and peripheral blood smears are normal. Aspiration biopsy...
Chondrosarcoma
Metastatic carcinoma
Osteochondroma
Osteosarcoma
1b
single
Multiple lytic lesions associated with keratin-positive cells strongly suggest metastatic bone cancer. Metastatic carcinoma is the most common tumor of bone, and skeletal metastases are found in at least 85% of cancer cases that have run their full clinical course. The vertebral column is the most commonly affected bon...
Pathology
Osteology
ef15f52d-dc57-45ca-8c4a-6b53211213a8
Preventable causes of Mental Retardation are
Downs
Phenylketonuria
Cretinism
Cerebral palsy
2c
single
Cretinism is congenital iron deficiency syndrome which can be preventable by intake in required amounts. Reference: GHAI Essential pediatrics, 8th edition
Pediatrics
Central Nervous system
389452f0-5f7b-4f38-ab3c-c6d78c028202
Medial border of Hesselbach's triangle is formed by:
Linea alba
Linea semilunaris
Inferior epigastric artery
Conjoint tendon
1b
single
Ans. (b) Linea semilunarisRef: Gray's 41st edn/1080-81; Keith L Moore clinical anatomy 4thed/ 193-4# HESSELBACH'S TRIANGLE* Medial border: Lateral margin the rectus sheath, also called linea semilunaris* Superolateral border: Inferior epigastric vessels* Inferior border: Inguinal ligament, sometimes referred to as Poup...
Anatomy
Abdominal Wall
757be73f-e0fc-4d08-89e6-b60cf98e500e
Which of the following are ineffective against gram negative bacteria?
Cefixime
Metronidazole
Vancomycine
Gentamycine
2c
single
Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria. Cefixine is an oral third generation cephalosporin antibiotic. It has good activity for gram-negatives. Metroridozole is highly active against gram-negative anaerobic bacteria, such as B. fragil...
Pharmacology
null
b71eccc6-e106-4e49-bc48-b43c3011965b
Ator fracture is -
Fracture neck of talus
Fracture scaphoid
Fracture calcaneum
Fracture 5th metatarsal
0a
single
Fracture neck of talus results from forced dorsiflexion of the ankle. Typically this injury is sustained in an aircraft crash where the rubber bar is driven forcibly against the middle of the sole of the foot (ATOR&;s fracture), resulting in forced dorsiflexion of the ankle, the neck being a weak area, gives way. Refer...
Orthopaedics
Management in Orthopedics
c178af37-f2a7-4cd1-bb63-25b185556035
A 4-month-old child presents with excessive irritability & crying, unexplained hyperpyrexia, vomiting, difficulty feeding for last 15 days. On admission he has rigidity & visual inattentiveness; CT scan brain shows the following finding. What is the probable diagnosis?
Alexander disease
Krabbe disease
Metachromatic Leukodystrophy
Adrenoleukodystrophy
1b
single
Bilateral basal ganglia calcification is seen on CT brain in Krabbe disease. Fuher,Globoid cells are seen in microscopic exmaination,which is a diagnostic feature. C/F: Irritability, muscle weakness, feeding difficulties, episodes of fever without any sign of infection, stiff posture, and delayed mental and physical de...
Pediatrics
Lysosomal Storage Diseases
f441f664-fec4-4970-b4b4-f5f7a4b61158
Raynaud’s syndrome occurs in all of the following except:
SLE
Rheumatoid arthritis
Osteoarthritis
Cryoglobulinemia
2c
multi
null
Surgery
null
dacfdced-7048-4713-bf0f-0c461fca2bb5
NVBDCP includes ail except?
Malaria
Filarial
Kala azar
KFD
3d
multi
Ans. is 'd' i.e., Chikungimya o National Vector Borne Disease control programme (NVBDCP) includes 6 vector borne diseases- Malaria Dengue Filaria Kala azar JE Chikungunya fever 1. Chickungunya has been included now Health programmes In India o Since India become indepedent, several measures have been undertaken by Nati...
Social & Preventive Medicine
Health Programmes in India
39438e31-fc04-4304-ab78-64715d578a1a
The usefulness of the technique of transcutaneous electrical nerve stimulation is explained by which of the following?
Allodynia
Central pain
Gate theory of pain
Referred pain
2c
multi
Transcutaneous electrical nerve stimulation is a method used to lessen severe, chronic pain by overly stimulating the involved neurons. This is thought to trigger inhibitory interneurons in lamina II of the spinal cord, thereby paially blocking the transmission of pain impulses. These interneurons are considered to be ...
Physiology
null
e598be7f-b11a-462f-97ee-7141f4b00ce1
Which is must for prothrombin time?
Thromboplastin
Prothrombin
Fibrinogen
Fibrin
0a
single
Prothrombin time test - Time needed for plasma to clot after addition of tissue thromboplastin and Ca2+ ions.
Pathology
null
0e0f0ba9-d515-449c-88cb-80739366e834
Fluroacetate inhibits -
Citrate synthetase
Aconitase
Succinate dehydrogenase
Alphaketoglutarate dehydrogenase
1b
single
B i.e. Aconitase
Biochemistry
null
460bbef5-309c-470c-a12f-e9e29117d465
Following angiography findings are most likely seen in which condition:
Kawasaki
PAN
Takayasu
Giant cell arteritis
1b
single
Ans. B. PANImage shows angiographic vascular pathologya. Most probably it is seen in PAN (Polyarteritis nodosa)b. It is medium vessel vasculitis of renal & visceral vessels sparing the pulmonary circulationc. In PAN, small aneurysms are strung like the beads of arosary known as Rosary sign.
Medicine
Immunology and Rheumatology
1f8f09e6-1e87-40a4-b1e0-b6d2e8f31adf
What is the approximate stress caused by polymerisation shrinkage of composite?
1 Mpa
5 Mpa
15 Mpa
30 Mpa
1b
single
null
Dental
null
be60c527-3987-4ffe-950d-b174f23602b0
Axillary hair growth is caused by?
Testosterone
Estrogen
Prolactin
Estrogen in women and androgens in man
0a
single
Testosterone REF: Ganong's 22nd ed p. 430 Secondary sexual hair production in both man and woman is under control of androgens
Physiology
null
b0fc9dda-c040-46dc-ba33-47b233cd9ba0
Neuronophagia is seen in -
Amoebic encephalitis
Poliomyelitis
Tuberculer meningoencephalitis
Cerebral malaria
1b
single
null
Medicine
null
cb5449fb-7ed9-49ea-a700-5a9d4e4303f3
A pulmonary disorder causes the alveoli to break down and coalesce into large air spaces. The lungs also lose elasticity and compliance is increased. A person who suffers from this disease will have
Increased dead air space
Increased vital capacity
Decreased PCO2 in the blood
Decreased anteroposterior diameter
0a
single
null
Medicine
null
5126f908-5636-43ae-befd-a3c60abcdd36
Triglycerides are maximum in
Chylomicrons
VLDL
LDL
HDL
0a
single
Ans. is 'a' i.e. Chylomicrons [Ref: Chatterjee & Shinde Biochemistry 6/e, p 338 (T21.2); Harper 26/e, p 206;Maximum content of TG's is seen in - Chylomicrons*Maximum content of exogenous TG's is seen in - Chylomicrons*Maximum content of endogenous TG's is seen in - VLDL*Maximum cholesterol is seen in - LDL*Chylomicrons...
Biochemistry
Cholesterol and Lipoproteins
2358d503-ba38-4962-96a3-f562d47b95d1
A 55 years lady presented with sudden onset of severe pain in the eye with, Shallow anterior chamber. Treatment of choice is
Atropine
I/V mannitol & Acetazolamide
Atenolol
Steroids I/V
1b
multi
(1/V mannitol & Acetazolamide): (242-Nema 6th edition; 244-Khurana 5th/e)It is a case of Acute primary angle closure glaucomaImmediate medical therapy to lower IOP1. Systemic hyper osmotic agents* Intravenous mannitol (1 gm 1 kg body weight)* Oral hyperosmotics eg glycerol2. Systemic carbonic anhydrase inhibitor eg ace...
Ophthalmology
Glaucoma
a72a3592-5628-4457-8a9d-99d21b195bd6
Which of the following structure passes through the triangular interval of the arm?
Radial nerve
Axillary nerve
Median nerve
Ulnar Nerve
0a
single
Ans. is 'a' i.e., Radial nerve RegionBoundariesContentsUpper triangular space of armSuperior: Teres minorInferior : Teres majorLateral: Long head of tricepsCircumflex scapular arteryLower triangular space of armSuperior: Teres majorMedial: Long head of tricepsLateral; Shaft of humerusRadial nerveProfunda brachii vessel...
Anatomy
Upper Extremity
fc63a9c7-7582-4fa0-aab7-60f59bed1bc5
What is the function of DNA ligase ?
Unwinding (denaturation) of dsDNA to provide an ssDNA template
Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand
Initiation of DNA synthesis and elongation
Initiates synthesis of RNA primers
1b
single
Ans. is 'b* i.e., Seals the single strand nick between the .......... ProteinFunctionDNA polymerasesDeoxynucieotide polymerizationHelicasesProcessive unwinding of DNATopoisomerasesRelieve torsional strain that results from helicase-induced unwindingDNA primaseInitiates synthesis of RNA primersSingle-strand binding prot...
Biochemistry
DNA Replication
abb49e0c-2fae-4259-aefd-bc3aa65b0303
Most common organ affected in blast injury:
Liver
Lungs
Nervous tissue
Skeletal system
1b
single
Lungs
Forensic Medicine
null
a2b6d667-4418-4fed-8bb4-067449bdcada
The cyclical flexion and extension motions of a leg during walking result from activity at which level of the nervous system?
Cerebral coex
Cerebellum
Globus pallidus
Spinal cord
3d
multi
The spinal cord has the intrinsic circuitry in the form of central paftern generators to produce the basic motions of walking.
Physiology
All India exam
7e8cdeba-c05b-4122-a61c-71b3b5b3b69f
Auerbachs plexus is present in the -
Colon
Esophagus
Stomach
All of the above
3d
multi
All of the above
Anatomy
null
10bab94e-6537-4408-9023-61049290c80e
A person of 60 years age is suffering from myositis ossificans progressive. The usual cause of death would be:
Nutritional deficiency
Bed sore
Lung disease
Septicemia
2c
single
C i.e. Lung disease
Surgery
null
3d38919b-c151-4f05-97e2-8bb90e4ee93d
A 29-year-old woman on oral contraceptives presents with abdominal pain. A computed tomography (CT) scan of the abdomen demonstrates a large hematoma of the right liver with the suggestion of an underlying liver lesion. Her hemoglobin is 6, and she is transfused 2 units of packed red blood cells and 2 units of fresh fr...
Continue the transfusion and administer an antihistamine
Stop the transfusion and administer a diuretic
Stop the transfusion, perform bronchoscopy, and sta broad-spectrum empiric antibiotics
Stop the transfusion and continue suppoive respiratory care
3d
multi
The patient has TRALI or transfusion-related acute lung injury which manifests as respiratory distress, hypoxemia, and bilateral pulmonary infiltrates not due to volume overload. The treatment of choice is respiratory suppo, including mechanical ventilation, as needed. The major risk factor for TRALI is transfusion of ...
Anaesthesia
Miscellaneous
26a8ae0c-ec74-4613-80a8-e64bae766023
All are absolute contraindication of OCP except:
Pregnancy
Thromboembolic disorder
Hepatic failure
Endometriosis
3d
multi
Ans. D. EndometriosisOCP are contraindicated in pregnancy, hepatic renal failure, thromboembolic disorder, breast CA, hypertension, diabetes. But in case of endometriosis, it regulates the irregular bleeding which is non-contraceptive use of OCP.
Pharmacology
Endocrinology
e1c883ab-4c8a-4369-8ae0-8acdf635cdc5
Which of the following is not a part of ransons score?
Amylase
Lipase
ALT
None of the above
3d
multi
null
Surgery
null
19ee31a1-5165-4a5f-af13-84ee7062ff12
Which of the following statement on microalbuminuria is not true?
Cannot be detected by routine lab tests
Urine protein less than 30-299 pg/day is called microalbuminuria
Microalbuminuria is an independent risk factor for cardiovascular risk in diabetic patients
Microalbuminuria is the earliest marker of diabetic nephropathy.
1b
multi
The significance of microalbuminuria: Microalbuminuria is the finding of albumin in the urine not detectable by the urine dipstick which is sensitive to protein concentration > 1gm%. It precedes the decline in GFR and indicates the presence of renal and cardiovascular complications. Annual screening for microalbuminuri...
Medicine
Nephrology
66219d6f-18e1-4d72-99a3-a0c61e277f89
Which of the following antigens are associated with cicatricial pemphigoid?
BPAG2 and epiligrin
HLA DR5 and HLA B8
HLA DR52 and HLA DR3
HLA DQB2
0a
single
Cicatricial Pemphigoid: Autoimmune blistering disease associated with autoantibodies directed against basement membrane zone target antigens. Autoantibodies of IgG subclass, particularly IgG4, are associated with CP. IgA antibodies have also been detected. The two major antigens associated with CP are bullous pemphigo...
Pathology
null
da50b434-53c9-4330-b171-e93f8ed2c634
Local anaesthetics act by-
Na channel inhibition inside gate
Na channel inhibition outside gate
K channel inhibition inside gate
K channel inhibition outside gate
0a
single
Ans. is 'a' i.e., Na channel inhibition inside gate o Local anesthetics act by inhibiting Na+ channels from inside.Mechanism of action of LAo Local anaesthetics block generation and conduction of nerve impulse at all part of neuron where they come in contact, without causing structural damage.o Thus not only sensory bu...
Anaesthesia
Miscellaneous (Local and Regional Anesthesia)
84b48e7b-92d5-4a06-a9ab-e6f501769fbb
Which of the following proteins binds with free hemoglobin in the plasma -
Albumin
Haptoglobin
Pre-albumin
Ceruloplasmin
1b
single
null
Pathology
null
56b15f4d-6a33-42ee-ab9e-011a7b9e6d1d
38 years old Mala has Pap smear suggestive of HSIL.Colposcopy directed biopsy can reveal all, EXCEPT:
CIN-1
CIN-2
CIN-3
Cainsitu
0a
multi
Ans. is 'a' i.e., CIN-1 * As per Bethesda system:# Low-grade squamous intraepithelial lesion (L-SIL) = CIN I# High-grade squamous intraepithelial lesion (H-SIL) = CIN II/CIN III/CIS
Gynaecology & Obstetrics
Miscellaneous (Gynae)
b33b9fc0-c517-4f35-ac53-4e3dd4251ef9
Mikulicz and russel bodies are characteristic of -
Rhinoscleroma
Rhinosporidiosis
Plasma cell disorder
Lethal midling granuloma
0a
single
Ans. is 'a' i.e., Rhinoscleroma o Biopsy of rhinoscleroma show's infiltration of submucosa writh plasma cells, lymphocytes, eosinophils, Mikulicz cells and Russell bodies. The latter two are the diagnostic features of the disease,Rhinoscleromao The causative organism is Klebsiella rhinoscleromatisor Frisch bacillus ^ w...
ENT
Nose and PNS
a5ed5279-5bad-405b-bee6-7ba071121859
Neurotransmitter in striatal pathway is?
Glutamine
Glycine
Serotonine
Dopamine
3d
single
The nigrostriatal pathway or the nigrostriatal bundle (NSB), is a dopaminergic pathway that connects the substantia nigra with the dorsal striatum (i.e., the caudate nucleus and putamen). Dopaminergic neurons of this pathway synapse onto GABAergic neurons. Glycine is an inhibitory neurotransmitter in the central nervou...
Medicine
C.N.S
911e5564-6383-428f-9beb-63acb5cefa9e
Which of the following pathways does not occur in mitochondria
Beta oxidation
Urea cycle
Fatty acid synthesis
Heme synthesis
2c
single
Fatty acid synthesis takes place in cytoplasm. Beta Oxidation occurs in mitochondria. Heme synthesis and Urea cycle occur both in cytoplasm and mitochondria.
Biochemistry
null
5b84a6f9-a25e-49b6-b159-d85dc8d75ffb
The above shown device is used for:
Gestational age assesment
Non-stress test
Fetal aerial doppler
Detect progression of labour
1b
multi
The above shown device is NST. The nonstress test measures the fetal hea rate in response to fetal movement over time. The term "nonstress" means that during the test, nothing is done to place stress on the fetus. If two or more accelerations occur within a 20-minute period, the result is considered reactive or "reassu...
Gynaecology & Obstetrics
Intra Uterine Growth Restriction, Intrapaum and Antepaum Fetal Surviellance
9c3f887a-df4c-4395-9984-c82a4fdf69dd
Which index would you use to assess the severity of periodontitis in epidemiological studies of a large population?
PMA index
Gingival index
Periodontal index
Sulcus bleeding index
2c
single
null
Dental
null
1efe6acc-bb2e-40b5-97d6-c4f550e6340d
True about tongue cancer:
Most common type is adenocarcinoma
Cervical lymph node metastasis is universally present
MC site is on Lateral margin
Slurring of speech is a common complaint
2c
multi
Ans. (c) MC site is on Lateral marginRef. Bailey & Love 26th ed. 713-14TONGUE CANCER* MC site is middle of lateral border or ventral aspect of the tongue.* MC histological type is squamous cell carcinoma.* MC complaint: Mid-irritation of tongue.* MC associated risk factors are tobacco and alcohol.* MC variety is ulcera...
Surgery
Oral Cavity
e1ea77c2-eaa8-4aad-a2e9-9f28f589430a
Gottron’s papules Seen in?
SLE
MTCD
Dermatomyositis
Rheumatoid arthritis
2c
single
DERM ATOM MYOSITIS: DM is a distinctive entity identified by a characteristic rash accompanying, or more often preceding muscle weakness. √ Heliotrope rash: The rash may consist of a blue-purple discolouration on the upper eyelids with edema √ Gottron's sign: A flat red rash on the face and upper trunk and erythema of...
Dental
null
5585da3c-5132-4b3d-89f5-cd27c8172713
A 67-year-old man with an 18-year history of type 2 diabetes mellitus presents for a routine physical examination. His temperature is 36.9 C (98.5 F), his blood pressure is 158/98 mm Hg and his pulse is 82/minute and regular. On examination, the physician notes a non tender, pulsatile, mass in the mid-abdomen. A plain ...
Atorvastatin
Cholestyramine
Clofibrate
Gemfibrozil
1b
single
Cholestyramine and colestipol are bile acid sequestrants that bind bile acids in the intestine, thereby interrupting enterohepatic circulation of bile acids. This has an indirect effect to enhance LDL clearance and lower lipids in the blood. Atorvastatin and lovastatin are lipid-lowering drugs that competitively inhibi...
Pharmacology
null
e0ea07e2-0b11-460c-9531-bf5b2869e457
Patient says he hears music every time when someone touches his thumb. This is an example of
Reflex hallucination
Functional hallucination
Visual hallucination
Extra campine hallucination
0a
multi
Functional hallucination : Here the stimulus and perecption are in same modality. v/s Reflex hallucination : Here the stimulus and pereception are in different modality.
Psychiatry
null
2abf9bf3-ef66-47a1-9de8-ffdeb8101fc6
Epipharynx is also called-
Nasopharynx
Oropharynx
Laryngopharynx
Hypopharynx
0a
multi
Ans. is 'a' i.e., Nasopharynx Epipharvnx / Nasophavnxo The part of the pharynx that lies above the soft palate; anteriorly it opens into the nasal cavities through the choanae;inferiorly, it communicates with the oropharynx through the pharyngeal isthmus; laterally it communicates withtympanic cavities through pharyngo...
ENT
Anatomy and Physiology of Pharynx
e4683651-a4c6-443f-a3a8-5c882269a11b
Red man syndrome is caused by which drug:
Linezolid
Clindamycin
Vancomycin
Teicoplanin
2c
single
Vancomycin is a glycopeptide antibiotic that releases histamine leading to "Red man syndrome"
Pharmacology
null
debc39c4-3315-4559-9a24-c93a240aab7f
DOC for migraine prophylaxis -
Propranolol
Valproate
Topiramate
Ethosuxamide
0a
single
Ans. is 'a' i.e., Propranolol Treatment and prophylaxis of migraineo For aborting an acute attack of migraine, sumatriptan (or any other triptan) is the drug of choice. Other drugs used for treatment are NSAIDs, ergotamine and dihydroergotamine, and intranasal butorphanol.o For Prophylaxis, Beta-blocker (propranolol) i...
Pharmacology
C.N.S
78e7c4bc-7be2-4446-bba1-73c287412e59
The percentage of copper in high copper alloy is:
10-12%
0 -6%
13-30%
20 -30%
2c
multi
null
Dental
null
da583f70-011e-43ad-9cb6-a17424c004a7
Which ligament transfers weight from peripheral to axial skeleton?
Coracoclavicular ligament
Acromio-clavicular ligament
Ligament of Bigelow
Stemo-clavicular ligament
0a
single
The gap anteriorly is filled by a syol bursa. The coracoclavicular ligaments have a vital role to play in movements of the pectoral girdle. The conoid ligament limits anterior movement of the scapula with respect to the clavicle. The trapezoid limits posterior movement between these two bones
Anatomy
General anatomy
05cb7042-9c17-4dc4-bb9f-7d56f3a27da6
Most common cause of stridor after birth:
Laryngeal papilloma
Laryngeal web
Laryngomalacia
Vocal cord palsy
2c
single
(c) Laryngomalacia(Ref. Current Diagnosis & Treatment Otolaryngology, Lalwani, 3rd ed., 481; Scott Brown, 8th ed., Vol 2; 333)Laryngomalacia, which is the most common congenital anomaly of the larynx, is the most common cause of congenital laryngeal stridor.Vocal cord palsy is the 2nd most common cause of congenital st...
ENT
Congenital Lesions and Stridor
1adfd3e2-fdff-430c-aafd-69e0de77ddda
"Corner sign of park" is feature of:
Scurvy
Rickets
Battered baby syndrome
Sickle cell disease
0a
single
Ans. A. ScurvyScurvy-Radiographic findings:1. Osteoporosis2. Pencil thin cortex3. Wimberger's sign4. Trummerfeld zone of rarefaction5. Corner sign of Park6. Line of Frankel7. Subperiosteal hemorrhage
Radiology
Skeletal System
1a3122d3-eef4-42e4-8026-7d2d48812fea
Not true regarding retinal anatomy
Most of the layers of retina are absent at foveala
The layer of retina in contact with vitreous is retinal pigment epithelium
Posterior pole consists of optic nerve head and macula
Fovea has a zone where there is no blood supply
1b
multi
Layer in contact with vitreous is internal limiting membrane Foveal Avascular Zone- * No blood vessels in this zone * Geometric centre is centre of macula & Fixation point * Impoant landmark in FA * Ora serrata > Foveola: Thinnest pa of retina * Posterior Pole: Macula + Optic nerve head * Optic disc approx: 1.75 mm (H)...
Ophthalmology
Retina
60d9ec2d-fbb8-4ea5-98ed-4e55945cb383
Septum secundum arises from -
Bulbus cordis
Primitive ventricle
Primitive atrium
Sinus venosus
2c
single
Ans. is 'c' i.e., Primitive atrium o The primitive atrium is divided into left and right atria by interatrial septum which is formed by fusion of septum primum and septum secundum. The sequnece of events are as follows# Septum primum arises from the roof of common atrium (primitive atrium) and grows caudally towards se...
Anatomy
Pericardium & Heart