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135
55254e9d-0d82-4e84-b0db-54204312a9d2
The following enzyme is required for the hexose monophosphate shunt pathway:
Glucose-6-phosphatase
Phosphorylase
Aldolase
Glucose-6-phosphate dehydrogenase
3d
single
Glucose-6-phosphate is oxidized by NADP+ dependent Glucose-6-phosphate dehydrogenase (GPD). 6-phospho glucono lactone is formed. One molecule of NADPH is formed in the reaction. This is the rate-limiting step. Regulation is effected by this enzyme   Reference: Vasudevan 7th  ed, pg 130
Biochemistry
null
05c12aae-06d5-4e38-be86-9c6eda7aa538
Chronic Laxative abuse can result in the formation of which type of stone:
Xanthine
Cysteine
Ammonium urate
Struvite
2c
single
Ref. API Textbook of Medicine. Pg. 784   Urinary stones due to chronic laxative abuse is due to gastrointestinal loss of fluid and electrolytes leads to chronic depletion of urinary volume ,relative super saturation and many other pathophysiologic derangements . These calculi are generally radiolucent with uric acid an...
Unknown
null
7d8e60cd-1758-4bd5-b50b-b23d1a020f5d
Following are side effects of Nimodipine except ?
Hypotension
Flushing
Headache
Marked changes m GIT motility
3d
multi
Ans. is 'd' i.e., Marked changes in GI motility Hypotension, headache, drowsiness, nausea, ankle edema, palpitation and flushing are common side effects of DHPs (including nimodipine). o Change in GI motility (constipation) is more common with verapamil.
Pharmacology
null
887c40ca-3a2b-43ba-ad61-bae6c5f06a00
Fetal exsanguination can occur if -
Vasa previa
Placentaprevia
Polyhydramnios
Oligohydramnios
0a
single
Ans. is 'a' i.e., Vasa previa Vasa previao In it a leash of blood vessels happens to traverse through the membranes overlying the internal os, in front of presenting part. Rupture of membranes involving the overlying vessels leads to vaginal bleeding. As it is entirely fetal blood, this may result in fetal exsanguinati...
Gynaecology & Obstetrics
Hydramnios and Oligo Hydramnios
a0bf81a8-ec70-4554-870b-0898e550e96e
First to be developed is -
Neural pit
Neural groove
Neural fold
Primitive streak
3d
single
null
Anatomy
null
8f2b3705-f079-426b-802c-204bf0f62e71
A G2P1 female at 35 weeks experiences uterine contractions. No fetal distress is seen and membranes are not ruptured. Which of the following is to be done?
12 mg betamethasone injection
Vaginal swab culture
Tocolytic therapy
Cervical cerclage
1b
single
12 mg beta methasone injection is is indicated in all pregnancies at risk of preterm labour between 28 and 35 weeks to attain LUNG MATURITY. Since there is no indication of fetal distress it is not given. Tocolytics are used to inhibit contractions and keep the uterus quiescent in case of preterm labour.But it is not i...
Gynaecology & Obstetrics
Abnormal labor
22f4cb9a-55ab-40a9-80d7-8b11126bfae1
Corneal thickness is measured using -
Pachymetry
Keratometer
CT scan
Aesthisiometry
0a
single
Ans. is 'a' i.e., Pachymetry o Corneal Pachymetry: It is the method to measure the corneal thicknesso The following are the other methods of measuring corneal thickness:a) Ultrasoundb) Ultrasound biomicroscopy and very high frequency ultrasoundc) Optical slit lamp pachymetryd) Specular microscopy basede) Scanning slit ...
Ophthalmology
Cornea
a33edf90-0ae4-4b19-a10c-42b5500161e5
A hypeensive patient who is a chroic smoker presented with recurrent hemoptysis. On examination he had cushingoid features. Investigations revealed raised ACTH levels not suppressed by dexamethasone. The single diagnosis which can account for all his symptoms is
Multiple endocrine neoplasia I
Pituitary adenoma
Adrenocoical adenoma
Ectopic ACTH producing tumor
3d
multi
Harmonies produced by small cell carcinoma ACTH,ADH,CALCITONIN,GONADOTROPIN. Ref Davidson edition23rd pg 601
Medicine
Respiratory system
34ba77fd-6010-472b-bf04-1f4cfc7de56c
The following neurotransmitter is synthesized from choline and acetyl-CoA:
Acetylcholine
Glutamine
Aspaate
NO
0a
single
Acetylcholine is seen in synaptic vesicles in high concentration in the terminals of cholinergic neurons. It is synthesized in the nerve terminal from choline and acetyl-CoA by the enzyme choline acetyltransferase (ChAT). Choline used in the synthesis of acetylcholine is transpoed from the extracellular space into the ...
Biochemistry
null
6039080a-1c9c-4ffe-920d-ca4b9effcc67
True about Trichotillomania is
Irresistible desire to set fire
Irresistible desire to steal things
Associated with patchy hair loss
Pathological gambling
2c
multi
(C) Associated with patchy hair loss # TRICHOTILLOMANIA (compulsive hair-pulling)> It is characterized by noticeable hair loss caused by person's persistent and recurrent failure to resists impulses to pull out hair.> There is an intense urge to pull out hair with mounting tension before the act and a sense of relief a...
Psychiatry
Miscellaneous
4f90573b-d9d2-48a3-a77e-91e6ed5e2b18
A female patient with signs of meningitis and CSF showing gram positive cocobacilli, which is showing characteristic tumbling motility. Diagnosis is
Listeria
Meningococcus
H. influenzae
Pneumococcus
0a
single
Ans. is 'a' i.e., Listeria Information in this question are :- Gram positive Cocobacilli Tumbling motility Listeria is gram positive coccobacilli and shows characteristic tumbiling motility when grown at 25degC. Other options can easily be excludes as no one has tumbling motility (charactristic of Listeria) and no one ...
Microbiology
null
99a257c2-db1a-491b-8762-c9a882dc60fd
Sterilization is commonly performed at which site of fallopian tube:
Ampulla
Infundibulum
Isthmus
Cornua
2c
multi
I have given these 2 questions simultaneously so that you understand how the answer changes as the options of the question change. Sterilization is done at the junction of proximal and middle third—the loop formed consists mainly of isthmus and part of the ampullary region of the tube. Therefore, if in options isthmoam...
Gynaecology & Obstetrics
null
6b71832b-e27e-402e-b682-259088252b49
Pisiform bone articulates with?
Triquetral
Lunate
Scaphoid
Trapezoid
0a
single
Ans. (a) TriquetralRef: Snell's 8th ed / 402
Anatomy
Hand
39cfe246-9481-4ccb-843d-b8e8346a01b1
Features of intestinal obstruction : clinically/investigation by :a) Abdominal distensionb) Vomitingc) Fluid level in X-ray > 4d) Localized tendernesse) Diarrhea
ac
a
ad
ab
3d
multi
About option 'c' > 5 air-fluid levels in x-ray abdomen suggest intestinal obstruction Grainger's Diagnostic radiology writes - "3 to 5 fluid levels less than 2.5 cm in length may be seen, particularly in the right lower quadrant, without any evidence of intestinal obstruction or paralytic ileus."
Surgery
null
f46abc40-015c-4d3b-8fdb-54af90876e3b
Main drawback of calcium hydroxide apexification compared with MTA:
More treatment time
Incomplete apical barrier
Incomplete coronal barrier
Reduced physical strength of dentin
3d
single
Apexification with calcium hydroxide is almost similar when compared with MTA about given options, except achieved physical strength of dentin, which is comparatively less in Ca(OH)2.
Dental
null
e38d91ae-3f25-436e-95b8-5c984074703b
Face bow measures relationship of maxilla to
Opening & closing axis
Mandible
Zygomatic bone
None of the above
0a
multi
null
Dental
null
4c02e6c0-796e-498e-8923-af96d61f88c5
All of the following statements about inhaled tooth fragment are true EXCEPT
It usually enters the right bronchus
It may cause Lung abscess
It may cause bronchiectasis
It will be coughed out spontaneously no treatment is necessary
3d
multi
null
Surgery
null
5692f3f7-5148-431d-a9e4-77a6db82cdab
An asymptomatic old patient presents with bruit in the carotid artery. Which of the following is the investigation of choice?
Doppler ultrasonography
Internal carotid angiography
Aortic arch angiography
Spiral CT angiography
0a
single
Bruit over carotid artery suggests carotid artery stenosis. Duplex scanning (B-mode scan and doppler ultrasonic velocimetry) is the method of choice for assessing the degree of carotid stenosis.
Radiology
null
d0bdc0c5-7bbf-42b6-b1ea-db380b9989a7
Computer controlled injection system is called:
CCD
WAND
CCI
JET
1b
multi
WAND: It is computer controlled injection system Dosage is controlled by computer.
Dental
null
aebc9e17-68e4-4d78-ad6c-48bf16104c65
Which of the following disease is seen only in females?
Autism
Asperger's syndrome
Retts disease
Colard'd disease
2c
single
ANSWER: (C) Rett's diseaseREF: Kaplan 9th ed p. 1215RETT SYNDROMEIt is a neurodevelopmental disorder of the grey matter of the brain that almost exclusively affects females.Normal prenatal and post natal growth, normal psychomotor development through first 5 months of life.The clinical features include small hands and ...
Psychiatry
Mood Disorders
d641f14b-a1f8-4de4-ba2b-5fef5d2bf0ed
Drug distribution in tissue true is all except ?
Chloroquine - eye
Ephedrine - bone
Digoxin - skeletal muscle
Minocycline - adipose tissue
1b
multi
Ans. is 'b' i.e., Ephedrine - bone
Pharmacology
null
951c6beb-03a6-4058-b00f-fad392c27f9c
A 25-year-old man presents 1 week after discovering that his left testicle is twice the normal size. Physical examination reveals a nontender, testicular mass that cannot be transilluminated. Serum levels of alpha-fetoprotein and human chorionic gonadotropin are normal. A hemiorchiectomy is performed, and histologic ex...
Desmin
Dystrophin
Cytochrome c
Telomerase
3d
single
The given histological examination is indicative of embryonal carcinoma. The tumor cells are large and have basophilic cytoplasm, indistinct cell borders, large nuclei, and prominent nucleoli.The neoplastic cells may be arrayed in undifferentiated, solid sheets or may form primitive glandular pattern. Somatic cells do ...
Pathology
General Concepts
39608ccd-b191-4c72-a498-8191d5e53e96
Tirofiban is a :
Monoclonal antibody
Antiplatelet drug
Anti-inflammatory drug
Antianginal drug
1b
single
null
Pharmacology
null
a699a9ad-8c95-4e5a-861c-7a69b1a4278e
Aortic sinus of Valsalva contributes to left ventricular outflow tract (LVOT) function by
Increasing aortic radius during ejection phase
Decreasing aortic regurgitation (normally)
Promoting non-turbulent flow in coronary arteries
All of the above
3d
multi
Ans. D (All of the above) (Ref. Gray's anatomy 39th ed., 1009, 1016)The right and left coronary arteries to originate from the right and left aortic sinuses (the sinuses of Valsalva), which are bulges at the origin of the ascending aorta immediately beyond, or distal to, the aortic valve.The left ventricular outflow tr...
Unknown
null
678d928c-21d3-47ac-9f11-e11f1db16d8c
Uterine sarcomas constitute about.................................... % of all malignant growth of uterus :
5
10
15
20
0a
multi
Ans. is a i.e. 5% Uterine sarcomas are rare tumors comprising 4.5 % of all malignant growths of uterus. The tumour arises most frequently in female between 40 - 50 years, rare before 30 years. Types of Sarcomas : Intramuraldeg - tumour arises in the myometrium (most common) - Consistency is soft and friable. The cut su...
Gynaecology & Obstetrics
null
fe8a30a2-bd2e-45bb-98af-07883128b069
Glucose is reabsorbed in which pa?
Early PCT
Henle loop
Collecting duct
Distal convoluted tubule
0a
single
Pa Reabsorption Secretion PCT Glucose 100% Amino acid 100% Na along with glucose by SGLT 2 Chloride (manly in late pa of PCT ) Bicarbonate Bile salts Hydrogen ion Creatinine Uric acid Drugs LOOP OF HENLE Descending limb - water Ascending limb - Na , k , Cl by 1NA 2Cl 1k cotranspoer , Slight reabsorption of cation such ...
Biochemistry
FMGE 2018
03b5aa6d-5a20-4c1a-8515-382bb5736034
Sterility is caused by -
Vinca alkaloids
Alkylating agents
Antimetabolites
Actinomycin D
1b
single
Ans. is 'b' i.e., Alkylatings agents Alkylating agents may contribute to sterility by the following effects : Azoospermia in males Amenorrhea and ovarian atrophy in females Specific toxicity of impoant alkylating agents. o Cyclophosphamide ---> Cystitis, alopecia, SIADH o Ifosfamide ---> Cystitis, SIADH, neurotoxicity ...
Pharmacology
null
22fcd60a-9784-4ad8-a107-2d08d0d4b160
Which of the following immunoglobulins shows homocytotropism -
IgG
IgA
IgE
IgD
2c
single
IgE is an 8 S molecule. - resemble IgG structurally. - heat liable - an affinity for the surface of tissue cells paicularly mast cells of the same species. This feature is called homocytotropism. - the normal serum contains only traces of IgE ( a few nanograms per ml ) - greatly elevated levels in atopic conditions lik...
Microbiology
Immunology
8dcbb51e-0682-49c1-b216-0ee9c148fe81
1st product of tryptophan Catabolism
Kynurenine
Xantheurenic acid
Bradykinin
Melatonin
0a
single
Kynurenine is formed from tryptophan in presence of enzyme tryptophan pyrrolaseRef: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 239, fig 18.8
Biochemistry
Metabolism of protein and amino acid
fb42f13d-599b-4575-941d-f15c36830021
Radiation induced cataract is
Shield cataract
Antrior polar cataract
Posterior Subcapsular cataract
Alpo syndrome
2c
single
Radiation can cause Posterior subcapsular cataract Lens is the most sensitive pa of eye for radiation induced damage Miscellaneous Cataract impoant for PGMEE * Sunflower cataract: Wilson disease, chalcosis. * Polychromatic Lusture- Complicated cataract * Coicosteroid: Posterior subcapsular cataract. (Topical steroids c...
Ophthalmology
Cataract
17bd436d-a6b1-45e7-9df3-f2f192d600ca
Which of the following is a characteristic of physiological jaundice of newborn?
Appears within 1st 24 hours of life
Involves palms and soles also
Clinical jaundice usually disappears after 1 month age
It is always unconjugated hyperbilirubinemia
3d
multi
Physiological jaundice- always unconjugated hyperbilirubinemia
Pediatrics
Neonatal Jaundice
52379583-452a-49d7-8c42-45704016b002
A mother brought her 18 month boy to the pediatrician, with the complaint that her son did not have any teeth till now. All of the following can be the underlying causes EXCEPT:
Pierre Robin sequence
Cleidocranial dysostosis
Rickets
Hypothyroidism
0a
multi
Delayed Dentition QDef: When no Teeth Erupts By 13 Months of Age Impoant Causes Mnemonic - "FRIED Chop" - Familial - Rickets - Idiopathic - Endocrine (3 "hypos") 1. Hypo-pituitarism 2. Hypo-thyroidism 3. Hypo-parathyroidism - Down Syndrome - Cleido-cranial dysotosis (clavicles absent, large anterior fontanelle, supernu...
Pediatrics
Paediatrics
ca2f796b-ef9a-4d84-bc30-7313f37ed320
The drug of choice for the treatment of chlamydial infection is -
Ampicillin
Third generation cephalosporins
Metronidazole
Doxycycline
3d
single
null
Medicine
null
1a21e5af-cb65-4750-a5a2-568ffb8e2144
Galactorrheamy be associated with the use of all the following drugs except -
Methyldopa
Tricyclic antidepressants
Pyridoxine
Phenothiazine
2c
multi
Lactation in the absence of breast feeding is known as galactorrhea. Drugs causing galactorrhea are dopamine antagonists like antipsychotics (phenothiazines,butyrophenones),antidepressants, antiemetics and dopamine depleting drugs like reserpine , methyldopa .These dopamine antagonists elevate prolactin concentrations ...
Medicine
Endocrinology
5246fb47-b7f8-42d5-9c97-58816b386352
Ketamine is safe in
Raised ICT
Open eye injury
Ischemic hea disease
Severe shock
3d
single
D i.e. Severe Shock
Anaesthesia
null
624a5c82-b98b-4157-a113-6ce0f288b8e3
Commonest cause for hyperparathyroidism is
Single adenoma
Multiple adenomas
Single gland hyperplasia
Multiple gland Hyperplasia
0a
single
A parathyroid adenoma causes the affected gland to release more PTH than it should. This disrupts your calcium and phosphorus balance. This condition is called hyperparathyroidism. Ref ganong's review of medical physiology 25e
Physiology
All India exam
2be641d2-5744-4806-824e-c3cda06e8350
Which of the following is a Cluster B personality disorder?
Schiziod personality disorder
Narcissistic personality disorder
Dependant personality disorder
Anantastic personality disorder
1b
single
Narcissistic personality disorder is a cluster B personality disorder. Schiziod personality disorder is a cluster A personality disorder. Dependant & Anankastic personality disorders are cluster C personality disorder.
Psychiatry
null
cf6e8619-52ed-4282-a197-7d8af75b6188
A young man is with known heroin addiction is brought in the emergency in unconscious state. On examination, the patient has decreased bowel sounds, depressed respiration and pin point pupil. The treatment of choice for this patient is:
Oral natrexone
IV naloxone
Oral diazepam
Oral Buprenorphine
1b
single
Ref: Kaplan & Sadock's Comprehensive Textbook of Psychiatry 9th/1375-76,1384 The decreased bowel sounds, respiratory depression,pin point pupil and history of heroin addiction strongly points toward the diagnosis of acute opioid poisoning. The drug of choice for acute poisoning is intravenous naloxone.
Pharmacology
Central Nervous system
0e8b1df9-cb2e-44bf-a5b7-4f87bd00f473
Maximum sterilizing action is shown by which anti TB drug
Rifamipicin
INH
Pyrazinamide
Streptomycin
2c
single
Refer Katzung 13th/819 Pyrizanimde is most effective against slow growing bacteria inside macrophages Thus it possesses strong sterilizing activity
Pharmacology
Chemotherapy
f8a7225b-e250-4dec-bbbc-12f74c6bb754
Main source of energy in 1 min is -
Glycogen
FFA
Phosphates
Glucose
0a
single
Ans. is 'a' i.e., Glycogen Source of energy for muscular activityo The immediate source of energy for all muscle contraction is ATP, followed immediately by creatine phosphate.o In stemous exercise ATP store is sufficient only for 1-2 seconds and creatine phosphate for another 5-7 seconds.o Thus, energy rich phosphagen...
Biochemistry
Respiratory Chain
112594bc-90bf-445d-a26f-4444845aa069
Definition of sleep apnoea
>10 apnoeas during 7 hours of sleep
>30 apnoeas during 7 hours of sleep
>10 apnoeas during 2 hours of sleep
>30 apnoeas during 2 hours of sleep
1b
single
null
ENT
null
6bd6f6f3-22da-4d52-8ec1-fec50415e17a
A 26 year old lady has been on Olanzapine for the treatment of Schizophrenia. All of the following are the ATP III (Adult Treatment Panel) criteria for metabolic syndrome, except:
Abdominal obesity
Triglyceride > 150 mg/dl
Blood pressure > 130/85
LDL > 150 mg/dl
3d
multi
LDL is not included in metabolic syndrome criteria. All others are indicated. The new generation anti-psychotics like Olanzapine and Risperidone increases the risk of metabolic syndrome and increase the risks of cardiovascular disease. ATP III (Adult Treatment Panel) Criteria for Metabolic Syndrome is as follows: Abdom...
Medicine
null
4f3f2aa7-9c85-4705-a6dc-80c516f38e1f
APGAR scale in infant measures
Respiratory, Neurological, and Circulatory system
Respiratory, Neurologic, renal system
Neurological, renal, digestive system
Respiratory, Neurological and digestive system
0a
single
null
Medicine
null
e12d08da-a002-45f6-bdae-09f9c7221bd8
Cervical warts are seen with which HPV -
11,13
17,18
5, 8
6, 11
3d
single
Genital warts (anogenital warts or condyloma acuminata) is most commonly caused by low risk HPV that is HPV-6,11. High risk HPV  that is HPV-16,18, 31, 33, 45 can lead to cervical carcinoma.
Dental
null
bec41f8d-cdbe-4c46-b849-825117ec73cc
Breast milk at room temperature stored for?
4 hrs
8 hrs
12 hrs
24 hrs
1b
single
Ans. is 'b' i.e., 8 hrs
Pediatrics
null
1ee37513-4c6b-48c6-8da8-fa7244695f67
A women is exposed to multiple sex paners has 5 times increased risk for - Ca. Cx the attributable risk is -
20%
50%
80%
100%
2c
single
Ans. is 'c' i.e., 80%
Social & Preventive Medicine
null
01fa9ab4-c640-47a5-a5fb-03b44d5be98f
Not included in cerebellar nuclei
Dentate nuclei
Emboliform nuclei
Fastigial nuclei
Caudate nuclei
3d
single
There are 4 deep nuclei in cerebellum: dentate, globose, emboliform, & fastigial nuclei. Ref: Ganong&;s review of medical physiology; 23rd edition; pg:255
Physiology
Nervous system
23b5b056-1c2e-4910-a464-1b4ce2111ee3
In reproductive and child health programme,districts are divided on the basis of –
Crude birth rate & infant mortality rate
Crude birth rate & female literacy rate
Crude death rate & crude birth rate
Couple protection rate & infant mortality rate
1b
single
null
Social & Preventive Medicine
null
27650550-8c24-402e-be1e-2c191c4d5766
Which is not a NNRTI -
Ritonavir
Nevirapine
Efavirenz
Delavirdine
0a
single
Ans. is 'a' i.e., Ritonavir Antiretroviral drugsa) Nucleoside reverse transcriptase inhibitors (NRTIs) - Zidovudin, Didanosine, Zalcitabine, Stavudine, Lamivudine, Abacavir.b) Nucleotide reverse transcriptase inhibitor - Tenofovirc) Nonucleoside reverse transcriptase inhibitors (NNRTIS) - Nevirapine, Efavirenz, Delavir...
Pharmacology
Anti-Viral
84688a80-dd0f-4168-a1d9-1f6986f461cd
Amrinone acts by-
Inhibiting phosphodiesterase
ATPase inhibitor
Calcium channel blocker
IC/ channel opener
0a
multi
Ans. is 'a' i.e., Inhibiting phosphodiesterase o Amrinone inhibits phosphodiesterase III
Pharmacology
null
dde019be-3f6a-45e9-b4ac-8df223883316
"Annular herald patch" is found in
Pityriasis alba
Pityriasis rosea
Tinea capitis
Psoriasis
1b
single
Pityriasis roses is characterised by herald patch/ mother patch it is the first manifestation of disease in 50% of patients it is a well defined erythematous oval or round lesion 2-10 cm diameter with typical colarette of scale at the margin Most common sites - chest back,abdomen extremities. widespread rash appear aft...
Dental
Fungal infections, Scabies, Pediculosis
c6c26c3f-5259-4bad-95de-ac25bcc12483
Which of the following signs is classic for CT scanning in Graves ophthalmopathy:
Nodular muscle enlargement
Solitary muscle enlargement
Fusiform muscle enlargement with sparing of tendoms
Kinking of extraocular muscles.
2c
single
Ans. Fusiform muscle enlargement with sparing of tendoms
Ophthalmology
null
e74852ed-2a4b-4128-9294-151a214c8365
Neutropenia is seen in all except:
Scurvy
Aplastic anemia
Typhoid fever
Chloramphenicol
0a
multi
Ans: A (Scurvy) Ref: Harrison's Principles of Internal Medicine, 18 ed.Explanation:Severity of neutropenia based on the absolute neutrophil count (ANC) measured in cells per microliter of blood:Mild neutropenia (1000 < ANC < 1500) minimal risk of infectionModerate neutropenia (500 < ANC < 1000) -- moderate risk of infe...
Medicine
Blood
b8996d65-ea76-4ee7-8d0c-65263144a1b0
Which of the following vessel is injured in Hemothorax patient?
Pulmonary aery
Pulmonary vein
Bronchial aery
Intercostal aeries
3d
single
"The most common cause of massive Hemothorax in blunt injury is continuing bleeding from torn intercostal vessels or occasionally from the internal mammary aery secondary to the fracture of ribs"
Surgery
Thorax And Mediastinum
833ec321-bf7e-43af-a100-4b8860f9666e
Responsible for epidemic dropsy is-
Sanguinarine
Ergot alkaloids
Pyrazolidine alkaloids
A flat ox in
0a
single
Ans. is 'a' i.e., Sanguinarine DiseaseToxinAdulterantLathyrismBOAAKhesari Dal (Lathyrus sativus)Epidemic DropsySanguinarineArgemone mexicana (oil)Endemic AscitesPyrrolizidine alkaloidsCrotolaria seeds (Jhunjhunia)AflatoxicosisAflatoxinA spergillus fiavus/parasiticusErgotismClavine alkaloidsClaviceps Jusiformis
Social & Preventive Medicine
Nutrition and Health
33c4541a-d39d-4619-8a56-70195f3aee53
Early strict toilet training can result in –
Nocturnal enuresis
Encopresis
Night terror
Temper tantrums
1b
single
null
Pediatrics
null
caaeafcc-5e2a-4e55-977b-562b973ecf2a
One of the following will always present with Bilious vomiting -
Pyloric stenosis
Esophageal atresia
Atresia of the 3rd part of the duodenum
Malrotation of the gut
2c
single
The CBD opens into the 2nd part of duodenum. So obstructions which are proximal to it like pyloric stenosis & esophageal atresia would not have bile in their associated vomits. Bilious vomiting would only occur if the obstruction is distal to CBD opening. Atresia of the 3rd part of duodenum would always produce bilious...
Surgery
null
00dd6465-084b-44fd-b64f-dbb33bbde0e0
A 7 year old child presents with non productive cough, mild stridor since 6 months. On oral antibiotics, patient is improving but suddenly develops wheezing, productive cough, mild fever. X-ray shows hyperlucency and PFT shows obstructive curve. Most probable diagnosis is -
Post viral syndrome
Bronchiolitis obliterans
Follicular bronchitis
Pulmonary alveolar microlithiasis
1b
single
Ans. is 'b' i.e., Bronchiolitis obliterance
Pediatrics
null
4492b962-da6e-4c98-97d2-d24f50ab6900
Human immunoglobulin is given in all except
Measles
Hepatitis B
Rabies
chickenpox
0a
multi
null
Social & Preventive Medicine
null
e51c9b6a-414b-4ee7-b7b5-2f08efcffafd
Cerebellar connection to other parts of the brain is projected through which cell?
Golgi cells
Basket cells
Purkinje cells
Oligodendrocytes
2c
single
Ans. C Purkinje cellsRef Gray's, 41sted. pg. 335-336* The axons of purkinje cells are the only output through cerebellar cortex.* However, it should be kept in mind that the output from the cerebellum is through deep nuclei, and purkinje cells axons generally pass to deep nuclei.
Anatomy
Neuroanatomy
cd6a441e-c5cd-4b80-8662-9c0f318cabe5
Immediate sustained permeability in cells is increased by:
Direct injury and necrosis
Endothelial gaps by histamine
Endothelial gaps by serotonin
Leucocyte mediated endothelial injury
0a
single
Direct endothelial injury, resulting in endothelial cell necrosis and detachment: This effect is usually encountered in necrotizing injury, and is due to direct damage to the endothelium by the injurious stimulus e.g. In severe burns or lytic lesions. Neutrophils adhere to the endothelium, and may also injure the endo...
Pathology
null
b70c5df7-1f19-4f5d-ab49-452a5201b7ca
Anal carcinoma is most commonly of type?
Adenocarcinoma
Epidermoid
Mixed
None of the above
1b
multi
Epidermoid carcinoma of the anus includes squamous cell carcinoma, cloacogenic carcinoma, transitional carcinoma and basaloid carcinoma. The clinical behaviour and natural history of these tumors is similar. Ref: Schwaz 9/e, Page 1053; Maingot's 10/e, Page 1505.
Surgery
null
9fb5b789-3ea7-4450-b4b6-c3c57cbfb0cd
Suprasellar calcification is a feature of:
Craniopharyngioma
Astrocytoma
Oligodendroglioma
Meningioma
0a
single
Craniopharyngioma
Radiology
null
da23ad08-bea6-4687-a13a-0d9f46829408
A patient present with dysphagia of 4 weeks duration. Now he is able to swallow liquid food only. Which of the following is the one investigation to be done
Barium studies
Upper GI endoscopy
CT scan
Esophageal manometry
1b
multi
investigations of carcinoma oesophagus includes, Barium swallow: Shouldering sign and irregular filling defect. * Oesophagoscopy to see the lesion, extent and type. * Biopsy for histological type and confirmation. * Chest X-ray to look for aspiration pneumonia. * Bronchoscopy, to see an invasion in upper third growth. ...
Surgery
G.I.T
8faa8605-6516-4e35-ae42-1dc2d22a7b47
The posterolateral lesion in the head of humerus in cases of recurrent anterior shoulder dislocation is:
Banka's lesion
Hill-Sachs lesion
Reverse Hill-Sachs lesion
Greater tuberosity avulsion fracture
1b
single
Complication of shoulder dislocation: Banka's anterior glenoid labrum: anterior tear in anterior dislocation Hill Sach's at head of Humerus: posterolateral defect in anterior dislocation Reverse Hill Sach's - anteromedial defect in posterior dislocation Light bulb signis seen on AP radiographs in theposterior dislocati...
Orthopaedics
Upper Limb Traumatology
9f598e0b-dedd-4abb-a18f-4541cd4453d2
Dean's technique refers to a form of
Radicular surgery
Cyst removal
Intraseptal alveoplasty
Mucoperiosteal flap
2c
single
null
Dental
null
5177654a-6b79-4977-8188-8386033f1cbe
The periphery of retina is visualized with:
Indirect binocular ophthalmoscopy
Direct opthalmoscopy
Contact lens
All
0a
multi
A i.e. Indirect opthalmoscopy Peripheral retina is visualized by indirect opthalmoscopy Q and biomicroscopy examination by Goldmann's three mirror contact lens. Q
Ophthalmology
null
691664a6-4a0e-4062-a5fc-4713afd75967
A case of severe mitral stenosis is associated with all of the following features, EXCEPT:
Pulsatile liver
Atrial fibrillation
Opening snap delayed from S2
Increase in the length of murmur
2c
multi
Severe mitral stenosis occurs with a valve area of less than 1 cm2 (The normal mitral valve orifice area is approximately 4-6 cm2). As the valve progressively narrows, the resting diastolic mitral valve gradient, and hence left atrial pressure, increases. This leads to transudation of fluid into the lung interstitium a...
Medicine
null
d0d3d7b2-c404-436a-8353-8fe0eb287179
The Cardinal movements in sequence in labour are :-
Engagement-flexion-descent-internal rotation-extension-ext. rotation
Engagement-flexion-descent-external rotation-expulsion
Engagement-descent-flexion-internal rotation-extension-external rotation
Engagement-extension-internal rotation-external rotation-expulsion
2c
single
Cardinal movements in sequence in labour are - Head floating-Engagement-Descent- Flexion -->Internal rotation-Extension- External rotation- Anterior shoulder delivered- Posterior shoulder delivered
Gynaecology & Obstetrics
Labour - normal, abnormal, malposition, malpresentation and their management
5bb03545-67cf-4549-a6f5-467caca1504e
The spaces involved in ludwigs angina are
Sublingual
Submandibular
Submaxillary
All of the above
3d
multi
LUDWIG'S ANGINA APPLIED ANATOMY :- Submandibular space lies between mucous membrane of the floor of mouth and tongue on one side and superficial layer of deep cervical fascia extending between the hyoid bone and mandible on the other. It is divided into two compaments by the mylohyoid muscle: 1. Sublingual compament (a...
ENT
Pharynx
7d887bc4-619f-4b11-a235-c29044e6140c
Drug of choice for Hairy cell leukemia
Methotrexate
Gemcitabine
Cladribine
Decitabine
2c
single
Cladribine is a purine analogue, which is  DOC for Hairy cell leukemia.
Pharmacology
null
79f8f128-76da-42d9-83cd-56237083dfb7
Drugs used for Prophylaxis of migraine include the following except?
Sumitriptan
Valproate
Serotonergic drugs
TCAs
0a
multi
null
Medicine
null
632be740-140b-4746-88b4-db3313f7408d
To observe a recurrent caries under a class II amalgam restoration, vertical angulation of the central Xrays should be
Perpendicular to the film placed
Perpendicular to theocclusal surface of the tooth
Parallel to the buccolingual plane of gingival surface of restoration
Perpendicular to the cavosurface bevels in the proximal box
2c
multi
null
Dental
null
3f44e058-4b55-4c19-8c4b-419b3568bc3a
Adult worm of Echinococcus granulosus is commonly seen in which of the given animals?
Dog
Cat
Sheep
Pig
0a
single
(A) Dog[?]Echinococcus granulosus:oOnly found in canine host (Dog or Wolf is Definitive Host)oIntermediate host - sheep or other ruminants. Human is accidental intermediate host.-Eggs ingested-Contaminated food or water-Objects contaminatedoDog becomes infected by eating raw meat containing hydatid cyst.[?]Life Cycle:o...
Microbiology
Parasitology
362b6c9a-e90e-4237-83d6-473d26f9af9d
Administrative unit of ICDS project in rural area is
PHC
Community development block
Zilla parishad
Gram panchayat
1b
single
The administrative unit of an ICDS project is the community development block in rural areas, the tribal development block in tribal areas and a group of slums in urban areas.Park 23e pg: 592
Social & Preventive Medicine
Maternal and child care
ae229c51-781c-4cb7-a93c-1eb1d851b37f
Histiocytic necrotizing lymphadenitis is
Kimura disease
Kikuchi disease
Hodgkin's disease
Castleman's disease
1b
single
Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a benign and self-limited disease that mainly affects young women. Patients present with localized lymphadenopathy, fever, and leukopenia in up to half of the cases.
Physiology
All India exam
d775a341-e4bc-471c-a930-0b433f5b29a1
What is the appropriate infusion time for the dialysate in your 38 y.o. patient with chronic renal failure?
15 minutes
30 minutes
1 hour
2 to 3 hours
0a
single
Dialysate should be infused quickly. The dialysate should be infused over 15 minutes or less when performing peritoneal dialysis. The fluid exchange takes place over a period ranging from 30 minutes to several hours.
Pathology
null
596a85ef-ae82-4e4b-94b0-aa55a4d080ff
During assessment of an analog X-ray film, the lights of a well lit operatory should :
Be made brighter
Not be changed
Be dimmed
Be put off
2c
single
Optimal viewing conditions should allow one to collimate the light, so the light area is restricted to the size of the film. The viewer’s eyes should be blocked to surrounding light to ameliorate perception of details. Also, the ambient light in the room should be dimmed so that more details in the radiographic image c...
Dental
null
546c3d32-0f98-4b7c-af8b-c50b4827bd9b
Comment on the diagnosis from the ECG shown below:
RCA occlusion by thrombus
LAD occlusion by thrombus
LCX occlusion by thrombus
Aefact
0a
single
ECG shows a hea rate of 100/min with ST elevation in lead II, III , aVF and V4R. Indicates inferior wall MI and occlusion of Right coronary aery.
Medicine
ECG and Arrhythmias 1
8dae3db1-b5b7-4a7e-be86-ace5ce84fd7a
All of the following cells are present in cerebellum, EXCEPT:
Purkinje cells
Stellate cells
Pyramidal cells
Basket cells
2c
multi
The pyramidal cells are seen in cerebral coex. The coex of the cerebellum consists of only three layers. They are, (1) an outer, molecular layer, (2) a middle, Purkinje layer, and (3) an inner, granular layer. The molecular layer has the least cellular density and consists of two types of neurons, stellate cells and ba...
Anatomy
null
571e5a1f-e1f3-4afa-89a1-351bc6d1f2d2
A 48-year-old male complains of abdominal pain that began about 6 months previously which is constant in nature, especially after meals and is located in the upper mid abdomen superior to the umbilicus. He also repos some heaburn that occurred during the previous year. He has been under significant stress and has been ...
NONE
C
A
B
2c
multi
A- Stomach B- Gallbladder C- Distal Ileum and caecum This patient has a history typical for peptic ulcer disease, that is, constant mid epigastric pain after meals. The patient also has symptoms consistent with gastro-esophageal reflux disease. The dark and tarry stools reflect blood in the stools; that is, hemoglobin ...
Unknown
Integrated QBank
8ce2b9f4-658b-4d92-b130-94e6036ca7a2
In which of these patients can a medial episiotomy be considered superior to a medio lateral episiotomy during delivery of fetus?
Nulligravida with thick perineum
Second stage arrest
Second gravida with moderate anemia
Before application of forceps
2c
single
A midline episiotomy is associated with higher risk of third and fouh degree lacerations and following factors are associated with an increased risk.: Nulliparity Second-stage arrest of labor Persistent occiput-posterior position, Midorlowforceps Use of local anesthetics Asian race. A medio lateral episiotomy should be...
Gynaecology & Obstetrics
Episiotomy
91c19d7a-66a0-47cf-b360-16f3304822ef
When do you intubate a burns patient?
Deep facial burns with singed nasal hair
Superficial facial burns
Pulse rate >100/min
Crepitations on auscultation
0a
single
Ans. (a) Deep facial burns with singed nasal hairRef: Bailey 26th edition, Page 388Indication of intubation in burns* Change in voice* Stridor* Deep burns around the mouth and in the neck
Surgery
Plastic & Reconstructive Surgery
6b799433-0065-4cdc-a2c7-e5f0e0614d44
Midostaurin is a new drug used for the treatment of:
CML
ALL
AML
CLL
2c
multi
Midostaurin : Multitargeted protein kinase inhibitor indicated along with standard cytarabine and daunorubicin for adult with newly diagnosed Acute Myeloid Leukemia (AML) who are FLT3 mutation positive.
Pharmacology
JIPMER 2017
6a673016-9cf2-46fb-aefe-71bce60af891
Plasma levels of hCG during pregnancy doubles every: September 2010
Daily
2 days
4 days
6 days
1b
single
Ans. B: 2 days Pregnancy tests may be used to determine the bility of a pregnancy. Serial quantitative blood tests may be done, usually 2-3 days apa. Below an hCG level of 1,200 mIU/ ml the hCG usually doubles every 48-72 hours, though a rise of 50-60% is still considered normal. Failure to increase normally may indica...
Gynaecology & Obstetrics
null
c89fa6fa-5791-4725-8f73-c5ff7eba2341
A pregnant woman with fibroid uterus develops acute pain in abdomen with low-grade fever and mild leukocytosis at 28 week. The most likely diagnosis is:
Preterm labor
Torsion of fibroid
Red degeneration of fibroid
Infection in fibroid
2c
single
Ans. is c, i.e. Red degeneration of fibroidRef: Shaw 15th/ed p355; Dutta Ohs 6th/ed p314; High Risk Pregnancy 2nd/ed p77The answer is quite obvious but let's see how other options can be ruled out.Option "a" Preterm laborPoints in favorPoints against* Patient is pregnant* Pain in abdomen at 28 weeks (preterm labor is w...
Gynaecology & Obstetrics
Gynaecological Disorders in Obs.
d7428ffc-1638-4763-b29d-f68626595b94
Socially attained behavior is:-
Culture
Acculturation
Socialization
Society
0a
multi
Culture: Is the learned behavior which is socially acquired. Acculturation: is 'cultural contact' or mixing of two cultures. Society: Is an organization of member agents characterized by 'system' - a system of social relationship between individuals. Socialization: is the process of inheriting norms, customs and ideolo...
Social & Preventive Medicine
Definition and Concepts in Sociology & Psychology
9a2bc26d-c423-4ada-a777-80e32ca149c7
ASO titire Is diagnostic in ?
SABE
Rheumatoid ahritis
Infective endocarditis
Acute rheumatic fever
3d
single
Ref: R Alagappan - Manual of Practical Medicine 4th Edition.pg no:146-147 Essential Criteria Evidence for recent streptococcal infection as evidenced by: 1. Increase in ASO titre a. > 333 Todd units (in children) b. > 250 Todd units (in adults). 2. Positive throat culture for streptococcal infection. 3. Recent history ...
Medicine
C.V.S
ac36165a-ad17-4eac-b102-1db616bb0061
Grynfeltt triangle not bounded by
12th rib
Paraspinal muscles
Internal oblique muscle
External oblique muscle
3d
single
Lumbar hernias- Hernias through the superior lumbar triangle (Grynfeltt triangle) are more common and bounded by the 12th rib, paraspinal muscles, and internal oblique muscle. Inferior Lumbar / Petit triangle- bounded by the iliac crest, latissimus dorsi muscle, and external oblique muscle.
Anatomy
All India exam
ad7d2399-3c4e-410b-b5ab-20d1c08936f2
Agar is prepared from:
Bullock heart
Chemicals
Seaweed
Chick cells
2c
single
Agar, a polysaccharide extracted from certain types of seaweed, is the main active ingredient in the material, while water is the major constituent in the agar impression material. Reference: PHILLIPS’ SCIENCE OF DENTAL MATERIALS, 12th ed page no 170
Dental
null
224fcfe4-ae22-415b-856d-17140250bd90
Which is the first study on water fluoridation?
Grand rapids (Michigan) & Muskegon
Newberg & Kingston
Brantferd & Sarnia
Evanston & Park
0a
single
null
Dental
null
dffe4c7b-5ec7-49aa-b915-a77cd2e89be3
All of the following features are seen in thrombotic thrombocytopenic purpura, except:
Fever
Haemolysis
Hypeension
Low platelets count
2c
multi
Thrombotic Thrombocytopenic Purpura is characterized by the pentad of hemolytic anemia, thrombocytopenia, neurologic symptoms, fever, and renal failure. It is not associated with hypeension. Ref: Harrison's Principle of Internal Medicine, 18th Edition, Pages 967, 969, Chapter 286
Medicine
null
d3a4fd19-5ab2-4e14-80d6-f110c0d6a070
Radioactive emissions used in radiotherapy are
Gamma rays
Alpha particles
Beta particles
X-ray
1b
single
null
Radiology
null
23fa6f67-0435-4956-8836-1b0d198ef43a
Insulin secretion is inhibited by
Secretin
Epinephrine
Growth hormone
Gastrin
1b
single
Epinephrine (also known as adrenaline or adrenaline) is a hormone and a neurotransmitter. Epinephrine has many functions in the body, regulating hea rate, blood vessel and air passage diameters, and metabolic shifts; epinephrine release is a crucial component of the fight-or-flight response of the sympathetic nervous s...
Physiology
Endocrinology
45870ae7-cee9-42b8-9a3c-a76d05d1e7ea
Most difficult site to remove cholesteatoma in sinus tympani is related with -
Anterior facial ridge
Posterior facial ridge
Epitympanum
Hypotymparum
1b
single
The sinus tympani (Posterior facial ridge) is the posterior extension of the mesotympanum and lies deep to both the promontory and facial nerve. The medial wall of sinus tympani becomes continuous with the posterior portion of the medial wall of the tympanic cavity. This is the worst region for access because it is abo...
ENT
null
3e83aa5e-1ba0-476c-b4b3-8a9c7a829951
All the following branches of the Vth nerve supply the dura mater except -
Anterior ethmoidal
Posterior ethmoidal
Auriculotemporal
Mandibular
2c
multi
The anterior cranial fossa is supplied by Anterior and posterior ethmoidal nerves (major supply); Nervus meninges medius (a branch of maxillary nerve); and nervus spinosus (a branch of mandibular nerve).
Anatomy
null
f57c20b1-6eab-4011-8d85-0f286fdfaa94
A four-fold increase in the titre obtained in Weil Felix reaction is diagnostic of -
Rickettsial infection
Fungal infection
Spirochetal infection
Viral infection
0a
single
null
Medicine
null
902b756b-e641-48d1-97ad-f9ce13996d37
Commonest posterior mediastinal tumour is:
Lung cyst
Neurofibroma
Dermoid
Thyroid
1b
single
Ans: b (Neurofibroma)Ref: Bailey & Love, 24th ed, p. 862, Fig (56.20) & 23rd ed p. 791, Schwartz, 7th ed p. 772
Surgery
Neoplasia
92f87b5a-c2c3-4d03-bedb-d27f32204d38
All of the following are affected in Erb's palsy EXCEPT
Upper trunk of brachial plexus
Lower trunk of brachial plexus
Dorsal scapular nerve
Suprascapular nerve
1b
multi
(B) Lower trunk of brachial plexus # Erb's palsy: Most common type when the 5th and 6th cervical nerve roots are involved as in the upper trunk of brachial plexus.> Resulting paralysis causes the arm to lie on the side with extension of the elbow, pronation of the forearm and flexion of the wrist (waiter's tip).> Moro ...
Anatomy
Neuroanatomy
bd8340b0-7b47-4664-a5a8-d1b52ad09cd9
String sign in angiography is suggestive of:
Aerial dissection
Aoa aneurysm
Stroke
None of the above
0a
multi
Traditional angiography remains the basis of diagnosis and characterization of aerial dissection. Angiographic abnormalities include stenosis of the true lumen, or "string-sign," visible intimal flaps, and the appearance of contrast in the false lumen. Four-vessel cerebral angiography should be performed when suspicion...
Surgery
null