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42437677 | 10.1542/peds.2025-075312 | Caregiver-Reported Quality of Pediatric Primary Care Language Services | Caregivers who use languages other than English (LOEs) experience health disparities. However, little is known about how spoken and written language services are experienced in pediatric primary care. The goal of this exploratory, cross-sectional study was to ask caregivers who use LOEs in health care about language se... | Pediatrics | Pediatrics | 2026 Aug 1 | 2,026 | [
"Yu L",
"Migliori O",
"Schweiberger K",
"Kurs-Lasky M",
"Schoemer P",
"Heidenerich K",
"Lion KC",
"DeCamp LR",
"Ray K",
"Chaves-Gnecco D",
"Saladino J",
"Ragavan MI"
] | Yu L | Ragavan MI | [
"Humans",
"Cross-Sectional Studies",
"Primary Health Care",
"Female",
"Male",
"Caregivers",
"Medical Interpreting",
"Communication Barriers",
"Child, Preschool",
"Child",
"Quality of Health Care",
"Pennsylvania",
"Pediatrics",
"Language",
"Infant"
] | [
"Journal Article"
] | 158 | 2 | null | null | 0031-4005 | eng | https://pubmed.ncbi.nlm.nih.gov/42437677/ | eOiN7RKT0bvVpVvB8 | d0GtUFdx7zKeUHgLi |
42423302 | 10.1111/ajr.70229 | Evaluating the Scale-Up and Sustainability of the Paediatric ESCALATION System in Country Western Australia: A Multi-Methods Study | To identify factors influencing implementation and integration of the paediatric ESCALATION system in country Western Australia. Health professionals (nurses and doctors) working in country Western Australia. A multi-methods study using an interpretive descriptive approach guided by the Practical Robust Implementation ... | Aust J Rural Health | The Australian journal of rural health | 2026 Aug | 2,026 | [
"Boyle E",
"Laird P",
"Leslie GD",
"Stokes S",
"Andrew J",
"Howard J",
"Robinson M",
"Harris T",
"Gill FJ"
] | Boyle E | Gill FJ | [
"Humans",
"Western Australia",
"Focus Groups",
"Child",
"Pediatrics",
"Program Evaluation",
"Rural Health Services",
"Child Health Services"
] | [
"Journal Article"
] | 34 | 4 | e70229 | pmc-id: PMC13348011; | 1038-5282 | eng | https://pubmed.ncbi.nlm.nih.gov/42423302/ | eOiN7RKT0bvVpVvB8 | d0GtUFdx7zKeUHgLi |
42418619 | 10.1056/CAT.25.0185 | The National Pediatric Readiness Quality Initiative: Empowering Emergency Departments to Improve Pediatric Care | Over 80% of all pediatric emergency visits occur in non-pediatric emergency departments (EDs). Continuous quality improvement (QI) is linked to higher pediatric readiness and improved patient outcomes, and, consequently, can lead to a 76% decreased mortality risk for critically ill and injured children. However, fewer ... | NEJM Catal Innov Care Deliv | NEJM catalyst innovations in care delivery | 2026 Jul | 2,026 | [
"Desai S",
"Edgerton E",
"Jensen AR",
"Remick K"
] | Desai S | Remick K | [
"Humans",
"Emergency Service, Hospital",
"Quality Improvement",
"Child",
"Pediatrics",
"Quality Indicators, Health Care",
"United States",
"Benchmarking"
] | [
"Journal Article"
] | 7 | 7 | CAT250185 | null | 2642-0007 | eng | https://pubmed.ncbi.nlm.nih.gov/42418619/ | eOiN7RKT0bvVpVvB8 | d0GtUFdx7zKeUHgLi |
42417972 | 10.1007/s00383-026-06510-7 | Laparoscopic training in porcine models: a tool for continuous professional skill enhancement for paediatric surgeons | Laparoscopic training is an established component of minimally invasive surgery education, and involves different tools: virtual reality, training box and in vivo models. The use of porcine models is the most similar to human anatomy. Its role is well known during the residency program, but its specific impact on paedi... | Pediatr Surg Int | Pediatric surgery international | 2026 Jul 8 | 2,026 | [
"Pensabene M",
"Patti M",
"Baldanza F",
"Grasso F",
"Cicero L",
"Sergio M",
"Di Pace MR"
] | Pensabene M | Di Pace MR | [
"Animals",
"Laparoscopy",
"Swine",
"Clinical Competence",
"Pediatrics",
"Male",
"Hernia, Inguinal",
"Humans",
"Models, Animal",
"Orchiopexy",
"Herniorrhaphy",
"Varicocele",
"Operative Time"
] | [
"Journal Article"
] | 42 | 1 | null | pmc-id: PMC13346154; | 0179-0358 | eng | https://pubmed.ncbi.nlm.nih.gov/42417972/ | eOiN7RKT0bvVpVvB8 | d0GtUFdx7zKeUHgLi |
42415970 | 10.17712/1658-3183.2810 | The Top 50 Cited Articles in Pediatric Neurology: A Bibliometric Analysis | To identify and analyze the most influential articles within the field of pediatric neurology through a bibliometric lens. As pediatric neurology continues to expand across subspecialties, identifying landmark studies is critical for understanding clinical and research priorities. Bibliometric analysis enables the eval... | Neurosciences (Riyadh) | Neurosciences (Riyadh, Saudi Arabia) | 2026 Mar | 2,026 | [
"Alyazidi A",
"Muthaffar O",
"Bamaga A",
"Qashqari H",
"Alhithlool A",
"Alanezi A",
"Almehmadi S",
"Babiker M",
"Bashiri F"
] | Alyazidi A | Bashiri F | [
"Bibliometrics",
"Neurology",
"Humans",
"Pediatrics",
"Journal Impact Factor",
"Periodicals as Topic"
] | [
"Journal Article"
] | 31 | 3 | 315-323 | pmc-id: PMC13340610; | 1319-6138 | eng | https://pubmed.ncbi.nlm.nih.gov/42415970/ | eOiN7RKT0bvVpVvB8 | d0GtUFdx7zKeUHgLi |
42415715 | 10.15766/mep_2374-8265.11616 | Perioperative Difficult Conversations With Guardians of Pediatric Patients: A Simulation-Based Workshop for Anesthesiology Practitioners Using the VitalTalk Framework | Effective communication of adverse events is a critical skill for health care practitioners, particularly those in anesthesiology. Despite the importance of delivering bad news to guardians after complications, many anesthesia practitioners receive little to no formal training in this area. This curriculum aims to addr... | MedEdPORTAL | MedEdPORTAL : the journal of teaching and learning resources | 2026 | 2,026 | [
"Phillips ML",
"Yanko F",
"Vermylen JH",
"Ballard HA"
] | Phillips ML | Ballard HA | [
"Humans",
"Anesthesiology",
"Communication",
"Simulation Training",
"Curriculum",
"Female",
"Male",
"Surveys and Questionnaires",
"Pediatrics",
"Parents",
"Child"
] | [
"Journal Article"
] | 22 | null | 11616 | pmc-id: PMC13337673; | 2374-8265 | eng | https://pubmed.ncbi.nlm.nih.gov/42415715/ | eOiN7RKT0bvVpVvB8 | d0GtUFdx7zKeUHgLi |
42545080 | 10.1002/mp.70596 | Photon minibeam-based LATTICE radiotherapy for small and medium-sized tumors: A dosimetric planning study | Lattice radiotherapy (LRT) is a spatially fractionated technique that delivers three-dimensional high-dose vertices within tumors. However, conventional LRT is constrained by geometric limitations when applied to small and medium-sized tumor volumes, primarily due to the large beam sizes that restrict optimal lattice p... | Med Phys | Medical physics | 2026 Aug | 2,026 | [
"Wu W",
"Shinde N",
"Li J",
"Vanhaezebrouck I",
"Jiang K",
"Lin Y",
"Li Q",
"Gao H"
] | Wu W | Gao H | [
"Photons",
"Humans",
"Radiotherapy Planning, Computer-Assisted",
"Monte Carlo Method",
"Brain Neoplasms",
"Radiometry",
"Tumor Burden",
"Lung Neoplasms",
"Radiotherapy Dosage"
] | [
"Journal Article"
] | 53 | 8 | e70596 | null | 0094-2405 | eng | https://pubmed.ncbi.nlm.nih.gov/42545080/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42544508 | 10.1093/bmb/ldag022 | Indirect calculation of metabolic power in soccer: a critical analysis of a popular model | The Global Positioning System (GPS)-based metabolic power model for soccer, proposed by di Prampero and applied by Osgnach, rests on a fixed energy cost (EC) of running of 4.6 J·kg-1·m-1 and a biomechanical equivalence between accelerated level and constant-speed uphill running. A narrative review was conducted via Pub... | Br Med Bull | British medical bulletin | 2026 Jul 3 | 2,026 | [
"Barba F",
"Padulo J",
"Maffulli N"
] | Barba F | Maffulli N | [
"Humans",
"Soccer",
"Energy Metabolism",
"Running",
"Biomechanical Phenomena",
"Geographic Information Systems",
"Athletic Performance",
"Models, Biological"
] | [
"Journal Article",
"Review"
] | 159 | 1 | null | null | 0007-1420 | eng | https://pubmed.ncbi.nlm.nih.gov/42544508/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42544118 | 10.2196/89801 | The Multicriteria Decision Analysis for Extended Reality (MCDA-XR) Governance Framework for Health Care Adoption: Mixed Methods Development Study | Health services increasingly face decisions about how to integrate immersive technologies into routine practice. International guidance highlights the need for structured governance in digital health, yet extended reality (XR) initiatives are often launched through isolated pilots without a clear assessment of organiza... | J Med Internet Res | Journal of medical Internet research | 2026 Jul 31 | 2,026 | [
"Ferrer Costa J",
"Armayones Ruiz M",
"Bourdin-Kreitz P"
] | Ferrer Costa J | Bourdin-Kreitz P | [
"Humans",
"Decision Support Techniques",
"Delivery of Health Care",
"Digital Health"
] | [
"Journal Article"
] | 28 | null | e89801 | null | 1438-8871 | eng | https://pubmed.ncbi.nlm.nih.gov/42544118/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42543682 | 10.2463/mrms.mp.2026-0101 | Structure-preserving Image-quality Enhancement for 3D Synthetic FLAIR Using a 3D U-Net with Content and Style Losses | Synthetic MRI can generate multiple contrasts from a single acquisition, yet synthetic fluid-attenuated inversion recovery (FLAIR) generally shows lower quality than conventional FLAIR. We aimed to improve 3D synthetic FLAIR image quality using deep learning, without losing the scan-time advantage of synthetic MRI. We ... | Magn Reson Med Sci | Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine | 2026 | 2,026 | [
"Kamio S",
"Hagiwara A",
"Otsuka Y",
"Nakaya M",
"Hosoi R",
"Hoshino Y",
"Tomizawa Y",
"Tsukamoto Y",
"Hara N",
"Kikuta J",
"Andica C",
"Akashi T",
"Wada A",
"Kusahara H",
"Yano R",
"Hatano T",
"Abe O",
"Kamagata K"
] | Kamio S | Kamagata K | [
"Humans",
"Imaging, Three-Dimensional",
"Magnetic Resonance Imaging",
"Image Enhancement",
"Deep Learning",
"Adult",
"Female",
"Male",
"Middle Aged",
"Demyelinating Diseases",
"Image Interpretation, Computer-Assisted",
"Aged"
] | [
"Journal Article"
] | 25 | 4 | null | null | 1347-3182 | eng | https://pubmed.ncbi.nlm.nih.gov/42543682/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42543556 | 10.47665/tb.43.2.011 | Temporal and spatial distribution of dengue in an urban setting: evidence from Hanoi, Vietnam (2018-2022) | Dengue fever remains a major mosquito-borne disease in Southeast Asia, with increasing incidence in rapidly urbanizing settings. In Vietnam, Hanoi has experienced recurrent outbreaks; however, comprehensive analyses of recent dengue epidemiology in northern regions remain limited. This study aimed to characterize the s... | Trop Biomed | Tropical biomedicine | 2026 Jun 1 | 2,026 | [
"Bau VH",
"Nguyen HN",
"Le MD",
"Hoang NS",
"Nguyen VK",
"Vu KT",
"Nguyen VA"
] | Bau VH | Nguyen VA | [
"Vietnam",
"Humans",
"Dengue",
"Incidence",
"Retrospective Studies",
"Seasons",
"Dengue Virus",
"Spatio-Temporal Analysis",
"Urban Population",
"Serogroup",
"Disease Outbreaks",
"Geographic Information Systems"
] | [
"Journal Article"
] | 43 | 2 | 211-218 | null | 0127-5720 | eng | https://pubmed.ncbi.nlm.nih.gov/42543556/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42543318 | 10.19540/j.cnki.cjcmm.20260119.501 | [Prescription patterns of Carthami Flos-containing compound formulas in intervention of diabetic peripheral neuropathy based on data mining] | Based on a data science perspective, this study systematically elucidated the prescription patterns and core compatibility mechanisms of Carthami Flos-containing formulas in the treatment of diabetic peripheral neuropathy(DPN), aiming to provide scientific evidence for optimizing evidence-based TCM therapeutic strategi... | Zhongguo Zhong Yao Za Zhi | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2026 Jun | 2,026 | [
"Zhang X",
"Wang H",
"Zhang XW",
"Gao G",
"Dan WC"
] | Zhang X | Dan WC | [
"Drugs, Chinese Herbal",
"Data Mining",
"Humans",
"Diabetic Neuropathies",
"Carthamus",
"Drug Prescriptions",
"Flowers"
] | [
"Journal Article",
"Review",
"English Abstract"
] | 51 | 12 | 3590-3600 | null | 1001-5302 | chi | https://pubmed.ncbi.nlm.nih.gov/42543318/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42543226 | 10.19813/j.cnki.weishengyanjiu.2026.04.005 | [Evaluating the taxonomy of Lacticaseibacillus casei in National Center for Biotechnology Information genome database based on whole-genome sequence analysis] | Reverificate the taxonomic information of Lacticaseibacillus casei in the genome database of National Center for Biotechnology Information (NCBI) to afford accurate genomic information for L. casei species-specific sequence analysis. Based on the whole genome sequence downloaded from NCBI database, the taxonomic inform... | Wei Sheng Yan Jiu | Wei sheng yan jiu = Journal of hygiene research | 2026 Jul | 2,026 | [
"Wang Q",
"Yang L",
"Wang W",
"Wei H",
"Wei Y",
"Li D",
"Zhang H"
] | Wang Q | Zhang H | [
"Phylogeny",
"Genome, Bacterial",
"Lacticaseibacillus casei",
"RNA, Ribosomal, 16S",
"Databases, Genetic",
"Whole Genome Sequencing",
"Sequence Analysis, DNA"
] | [
"English Abstract",
"Journal Article"
] | 55 | 4 | 558-566 | null | 1000-8020 | chi | https://pubmed.ncbi.nlm.nih.gov/42543226/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42543074 | 10.1002/pds.70448 | Prenatal Exposure to Modafinil and the Risk of Major Congenital Anomalies and Other Adverse Neonatal and Pediatric Outcomes | To assess the risk of major congenital anomalies (MCAs) and other adverse outcomes following prenatal exposure to modafinil. This retrospective cohort study used the French national healthcare database (SNDS) to include singleton children born between January 2009 and September 2024 of women aged 15-55 years. Prenatal ... | Pharmacoepidemiol Drug Saf | Pharmacoepidemiology and drug safety | 2026 Aug | 2,026 | [
"Kanoun M",
"Bouazza N",
"Treluyer JM",
"Collier M"
] | Kanoun M | Collier M | [
"Humans",
"Female",
"Modafinil",
"Pregnancy",
"Retrospective Studies",
"Prenatal Exposure Delayed Effects",
"Methylphenidate",
"Adolescent",
"Adult",
"Abnormalities, Drug-Induced",
"Central Nervous System Stimulants",
"Databases, Factual",
"Infant, Newborn",
"Young Adult",
"France",
"M... | [
"Journal Article"
] | 35 | 8 | e70448 | null | 1053-8569 | eng | https://pubmed.ncbi.nlm.nih.gov/42543074/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42542542 | 10.1186/s12903-026-09308-0 | Investigating demographic factors and geographical information mapping (GIS) of oral cancer in Golestan Province, Iran in 2014 to 2021 | Oral cancer is among the ten most common malignancies worldwide and can be highly lethal if not diagnosed and treated promptly. Mapping the spatial and geographic distribution of this cancer can assist health authorities in planning effective prevention, control, and treatment strategies by identifying its geographic a... | BMC Oral Health | BMC oral health | 2026 Jul 23 | 2,026 | [
"Ghelichli M",
"Roshandel G",
"Sohrabi S"
] | Ghelichli M | Sohrabi S | [
"Humans",
"Iran",
"Female",
"Mouth Neoplasms",
"Male",
"Adolescent",
"Middle Aged",
"Aged",
"Child",
"Child, Preschool",
"Adult",
"Incidence",
"Aged, 80 and over",
"Geographic Mapping",
"Young Adult",
"Geographic Information Systems",
"Registries"
] | [
"Journal Article"
] | 26 | 1 | null | pmc-id: PMC13429022; | 1472-6831 | eng | https://pubmed.ncbi.nlm.nih.gov/42542542/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42542529 | 10.1007/978-1-0716-5166-7_11 | Generation of High-Quality Succinyl Spectral Libraries for Improved Proteome-Wide Succinylome Analysis Using Data-Independent Acquisition | Protein posttranslational modifications (PTMs) are crucial and dynamic modulators of protein functions, interactions, and localizations, as well as biological pathways and cellular signaling. Lysine succinylation analysis remains challenging, but sophisticated workflows combining succinylated peptide enrichments and qu... | Methods Mol Biol | Methods in molecular biology (Clifton, N.J.) | 2026 | 2,026 | [
"Zhang A",
"Schilling B",
"Bons J"
] | Zhang A | Bons J | [
"Protein Processing, Post-Translational",
"Proteome",
"Proteomics",
"Software",
"Animals",
"Succinic Acid",
"Mice",
"Peptide Library",
"Tandem Mass Spectrometry",
"Databases, Protein",
"Peptides"
] | [
"Journal Article"
] | 3018 | null | 169-181 | null | 1064-3745 | eng | https://pubmed.ncbi.nlm.nih.gov/42542529/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42542519 | 10.1007/978-1-0716-5166-7_1 | An Overview of Mass Spectrometry-Based Methods to Analyze Post-Translational Modifications | Post-translational modifications (PTM) are the covalent modifications of proteins after their biosynthesis. PTMs change the structure and functions of proteins, which eventually regulate various biological processes that are closely related to the onset and development of diseases. Hundreds of different forms of PTMs h... | Methods Mol Biol | Methods in molecular biology (Clifton, N.J.) | 2026 | 2,026 | [
"Chen R",
"Zhang X",
"Li J"
] | Chen R | Li J | [
"Protein Processing, Post-Translational",
"Mass Spectrometry",
"Humans",
"Proteomics",
"Computational Biology",
"Proteins",
"Animals",
"Databases, Protein"
] | [
"Journal Article",
"Review"
] | 3018 | null | 3-21 | null | 1064-3745 | eng | https://pubmed.ncbi.nlm.nih.gov/42542519/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541705 | 10.1177/03000605261472034 | A clinical decision support system for predicting drug-related adverse effects in pediatric patients with congenital heart disease: Development and retrospective evaluation | ObjectiveChildren with congenital heart disease are highly vulnerable to drug-related adverse effects due to the use of complex polypharmacy. This study aimed to develop and retrospectively evaluate a hybrid clinical decision support system for predicting drug-related adverse effects in this population.MethodsThis two-... | J Int Med Res | The Journal of international medical research | 2026 Jul | 2,026 | [
"Toni E",
"Ayatollahi H",
"Abbaszadeh R",
"Fotuhi Siahpirani A"
] | Toni E | Fotuhi Siahpirani A | [
"Humans",
"Heart Defects, Congenital",
"Decision Support Systems, Clinical",
"Retrospective Studies",
"Child",
"Drug-Related Side Effects and Adverse Reactions",
"Female",
"Random Forest",
"Child, Preschool",
"Male",
"Machine Learning",
"Infant",
"ROC Curve",
"Predictive Learning Models",
... | [
"Journal Article"
] | 54 | 7 | 3000605261472034 | pmc-id: PMC13428899; | 0300-0605 | eng | https://pubmed.ncbi.nlm.nih.gov/42541705/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541450 | 10.1177/14791641261474099 | Analysis of the diabetic arterial transcriptome to define novel biomarkers of macrovascular disease | Diabetes mellitus (DM) approximately doubles the risk of atherosclerotic cardiovascular disease (ASCVD) events, but the molecular basis is poorly understood. Using RNA-sequencing data from two arterial sites in >90 people with DM and >330 controls, we defined differentially expressed genes (DEGs) associated with DM. UK... | Diab Vasc Dis Res | Diabetes & vascular disease research | 2026 Jul-Aug | 2,026 | [
"Shouma A",
"Giannoudi M",
"Conning-Rowland M",
"Drozd M",
"Brown OI",
"Cheng C",
"Sukumar P",
"Bridge KI",
"Levelt E",
"Bailey MA",
"Griffin KJ",
"Kearney MT",
"Cubbon RM"
] | Shouma A | Cubbon RM | [
"Humans",
"Transcriptome",
"Diabetic Angiopathies",
"Gene Expression Profiling",
"Case-Control Studies",
"Proteomics",
"UK Biobank",
"Risk Assessment",
"Biomarkers",
"Genetic Markers",
"Predictive Value of Tests",
"Male",
"Atherosclerosis",
"Female",
"Prognosis",
"Risk Factors",
"Mid... | [
"Journal Article"
] | 23 | 4 | 14791641261474099 | pmc-id: PMC13428926; | 1479-1641 | eng | https://pubmed.ncbi.nlm.nih.gov/42541450/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541323 | 10.6002/ect.2026.0152 | Development of A Novel Infection Risk Score for Prediction of Infections in Renal Transplant Recipients | In renal transplant recipients, infections can have atypical outcomes due to immunosuppression therapy, and delayed diagnosis causes high mortality. We developed an infection risk score in renal transplant recipients to rapidly predict infection risk in emergency departments. Of 870 renal transplant recipients admitted... | Exp Clin Transplant | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation | 2026 Jun | 2,026 | [
"Muratoglu M",
"Bulut B",
"Manevi AR",
"Yıldırım HS",
"Kilicoglu Tanir S",
"Cheraqi MS",
"Safak A",
"Yildirim S",
"Haberal M"
] | Muratoglu M | Haberal M | [
"Humans",
"Kidney Transplantation",
"Female",
"Risk Factors",
"Risk Assessment",
"Predictive Value of Tests",
"Retrospective Studies",
"Male",
"Adult",
"Middle Aged",
"Immunosuppressive Agents",
"Decision Support Techniques",
"Immunocompromised Host",
"Treatment Outcome",
"Emergency Serv... | [
"Journal Article"
] | 24 | 6 | 450-459 | null | 1304-0855 | eng | https://pubmed.ncbi.nlm.nih.gov/42541323/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541140 | 10.23889/ijpds.v11i5.3712 | CBS Microdata | CBS microdata is a valuable resource that provides researchers secure access to nearly all individual-level data available within Statistics Netherlands (CBS). The data is originated from administrative registers (e.g., Dutch Tax Authority, Personal records database (BRP)) and statistical surveys conducted by CBS. As s... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Slager T"
] | Slager T | Slager T | [
"Netherlands",
"Humans",
"Databases, Factual",
"Computer Security",
"Registries"
] | [
"Journal Article"
] | 11 | 5 | 3712 | pmc-id: PMC13426809; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541140/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541097 | 10.23889/ijpds.v11i5.3617 | How Data Linkage Is Applied to Build Longitudinally Linked Data and Genealogy Data Based on Massive Sources of Administrative Data: A Two-decade Research on Linking Taiwan Household Registers | My presentation uses data linkage to build data on Taiwan indigenous peoples (TIPs) as an example. TIPs used to be invisible and marginalized in Taiwan. In recent years, TIPs not only become very visible in Taiwan, but are also known globally. The most important contribution that helps TIPs become visible and are empow... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Lin J"
] | Lin J | Lin J | [
"Taiwan",
"Humans",
"Registries",
"Big Data",
"Longitudinal Studies",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3617 | pmc-id: PMC13426832; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541097/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541071 | 10.23889/ijpds.v11i5.3693 | Indexing First Research: understanding the quality of generalised data linkage processes | While data linkage has traditionally used bespoke, customer led methods, an increased demand for linked data has led to the development of indexes representing people, businesses and locations. Data are linked to indexes through generalised methods, and an index ID is appended to each statistical entity in the dataset.... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Lewis E",
"Cummins S",
"O'Connor N",
"Allen B"
] | Lewis E | Allen B | [
"Humans",
"Information Storage and Retrieval",
"Abstracting and Indexing",
"Data Accuracy"
] | [
"Journal Article"
] | 11 | 5 | 3693 | pmc-id: PMC13426769; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541071/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541040 | 10.23889/ijpds.v11i5.3533 | Handling missing data when using Goldstein et al.'s Scalelink method of data linkage | Scalelink is an innovative probabilistic data linkage method based on multiple correspondence analysis. Unlike the current gold-standard probabilistic algorithm, Fellegi-Sunter, it does not assume linkage variable independence. All real-world linkage contains dependent linkage variables. Thus, avoiding this assumption ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Cleaton M",
"Thomson G",
"Plachta J",
"Shipsey R"
] | Cleaton M | Shipsey R | [
"Algorithms",
"Humans",
"Information Storage and Retrieval",
"Models, Statistical"
] | [
"Journal Article"
] | 11 | 5 | 3533 | pmc-id: PMC13426765; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541040/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541036 | 10.23889/ijpds.v11i5.3715 | Real World Use of EHR data and Public Data Sets to Inform Public Health and Population Health Research and Surveillance | Across the United States, linking electronic health record (EHR) data with public health and other publicly available datasets remains a significant challenge due to the lack of a universal patient ID and limited interoperability. While technology exists to overcome these barriers, silos between primary care, tertiary ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Hamilton A",
"Sital S",
"VanDoren K"
] | Hamilton A | VanDoren K | [
"Electronic Health Records",
"Humans",
"United States",
"Population Surveillance",
"Public Health",
"Population Health",
"Digital Health",
"Primary Health Care",
"Datasets as Topic"
] | [
"Journal Article"
] | 11 | 5 | 3715 | pmc-id: PMC13426787; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541036/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541006 | 10.23889/ijpds.v11i5.3593 | Health and educational outcomes among adolescents with neurodisability in England: a population-based linked data study using ECHILD | Adolescents with neurodisability (neurological conditions causing functional limitations) have more complex needs than their peers, yet population-level evidence on secondary school outcomes remains limited. Using linked health and education records from the ECHILD database, we developed a national cohort of Year 6 pup... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Macaulay L",
"Saxton J",
"Ford T",
"Logan S",
"Harron K",
"Gilbert R",
"Shumway J",
"Nguyen V",
"De Stavola B",
"Totsika V"
] | Macaulay L | Totsika V | [
"Humans",
"Adolescent",
"Female",
"Male",
"England",
"Child",
"Education, Special",
"Educational Status",
"Databases, Factual",
"Nervous System Diseases",
"Health Status"
] | [
"Journal Article"
] | 11 | 5 | 3593 | pmc-id: PMC13426650; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541006/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42541000 | 10.23889/ijpds.v11i5.3756 | The influence of ethnic name characteristics on string similarities when linking large heterogeneous population databases | Comparing names is at the core of many data linkage applications. Names can be recorded with variations and errors (typographical, phonetic, or scanning, depending on how names have been captured). Furthermore, names can change over time. Therefore, approximate string comparison functions are commonly employed to calcu... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Dharmawimala Y",
"Christen P",
"Ziyad S",
"Vidanage A",
"Lam J",
"Schnell R"
] | Dharmawimala Y | Schnell R | [
"Names",
"Humans",
"Ethnicity",
"Databases, Factual"
] | [
"Journal Article"
] | 11 | 5 | 3756 | pmc-id: PMC13426649; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42541000/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540995 | 10.23889/ijpds.v11i5.3680 | An Experience-Driven Framework for Overcoming Challenges in Cross-Agency Data Linkage | Cross-agency data-sharing collaborations have proven crucial to ensure effective usage of often limited funds. Through, delivering these resources to the right people in the right circumstances at the right time. Despite the cumbersome and often time-consuming process of setting those collaborations up. The data linkag... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Scheliga B",
"Wilde K",
"Evans J",
"E Butler J",
"Berrocal-Martin R"
] | Scheliga B | Berrocal-Martin R | [
"Humans",
"Information Dissemination",
"Scotland",
"Information Storage and Retrieval",
"Cooperative Behavior"
] | [
"Journal Article"
] | 11 | 5 | 3680 | pmc-id: PMC13426659; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540995/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540987 | 10.23889/ijpds.v11i5.3648 | Hospital Electronic Health Records as a research resource: data linkage, national scale-up, and five-year Impact of the National Centre for Healthy Ageing Data Platform | Established in 2020, the National Centre for Healthy Ageing (NCHA) Data Platform is Australia's first linked hospital-based electronic health record (EHR) research database covering all residents within a geographic region. Recent activities have expanded its scope, reach, and innovation. The platform houses internally... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Andrew N",
"Beare R",
"Mann E",
"Parikh S",
"Carver A",
"Collyer T",
"Ung D",
"Dhillon R",
"Srikanth V"
] | Andrew N | Srikanth V | [
"Electronic Health Records",
"Humans",
"Australia",
"Medical Record Linkage",
"Databases, Factual",
"Healthy Aging",
"Hospitals",
"Digital Health"
] | [
"Journal Article"
] | 11 | 5 | 3648 | pmc-id: PMC13426665; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540987/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540986 | 10.23889/ijpds.v11i5.3748 | Capitalising on administrative data to innovate and drive evaluation excellence | Administrative Data Research (ADR) is transforming evaluation practice by improving robustness, complementing more traditional methods, and enabling evidence-based decision-making. In Wales, ADR Wales has embedded administrative data linkage into all Welsh Government evaluability assessments as standard practice, ensur... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Gracey F",
"Davies H"
] | Gracey F | Davies H | [
"Databases, Factual",
"United Kingdom",
"Wales",
"Routinely Collected Health Data"
] | [
"Journal Article"
] | 11 | 5 | 3748 | pmc-id: PMC13426666; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540986/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540976 | 10.23889/ijpds.v11i5.3628 | Educational Outcomes for Children in Intergenerational Households with Substance Misuse: A National Data Linkage Study in Wales, UK | Parental substance misuse is a known risk factor for adverse child outcomes, yet large-scale UK evidence linking household misuse across health and justice systems to education remains limited. This study leverages whole-population linked administrative data in Wales to address this gap, operationalising policy commitm... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Farr I",
"Turner Evans H",
"Bailey G",
"Davies G",
"James D",
"Smith J"
] | Farr I | Smith J | [
"Humans",
"Wales",
"Substance-Related Disorders",
"Retrospective Studies",
"Child",
"Adolescent",
"Female",
"Male",
"Educational Status",
"Family Characteristics",
"Risk Factors",
"Socioeconomic Factors",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3628 | pmc-id: PMC13426804; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540976/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540975 | 10.23889/ijpds.v11i5.3520 | Linking population-level education and hospital data in England: who are we missing in ECHILD? | Linkage of National Pupil Database (NPD) to national hospital data has the potential to provide almost universal population coverage of children and young people in England. However, quantifying who is missed is a key requirement for producing unbiased population estimates. Deterministic linkage was conducted between l... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Nguyen V",
"Ramzan F",
"Ruiz Nishiki M",
"Blackburn R",
"Gilbert R",
"Harron K"
] | Nguyen V | Harron K | [
"Humans",
"England",
"Female",
"Male",
"Child",
"Adolescent",
"Educational Status",
"Databases, Factual",
"Hospitals",
"Child, Preschool"
] | [
"Journal Article"
] | 11 | 5 | 3520 | pmc-id: PMC13426679; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540975/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540955 | 10.23889/ijpds.v11i5.3547 | Building the Longitudinal Education Outcomes Northern Ireland (LEO NI) Dataset: Linking Administrative Data for Policy Impact | This paper introduces the Longitudinal Education Outcomes Northern Ireland (LEO NI) dataset-an anonymised, research-ready resource that exemplifies the transformative potential of administrative data linkage. LEO NI integrates school-level records for individuals aged 14+ across eight academic years with seven years of... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Wilgar P",
"McCullough N",
"Norris E",
"Foley B",
"Ross J"
] | Wilgar P | Ross J | [
"Northern Ireland",
"Humans",
"Longitudinal Studies",
"Educational Status",
"Datasets as Topic"
] | [
"Journal Article"
] | 11 | 5 | 3547 | pmc-id: PMC13426728; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540955/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540932 | 10.23889/ijpds.v11i5.3588 | Can and should we? Use of maternal administrative data to identify children at risk of poor outcomes | Millions of children in the UK experience early adversity, with many requiring children's social care (CSC) support. National longitudinal data on these children is essential to understand lifelong impacts on health and development, yet they are often excluded from the UK's leading child development studies. This study... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Jane Griffiths L",
"Raybould A",
"Dennison K",
"Harron K",
"Bailey G"
] | Jane Griffiths L | Bailey G | [
"Humans",
"Female",
"Risk Factors",
"Mothers",
"Child",
"Wales",
"Child, Preschool",
"Infant",
"Databases, Factual",
"United Kingdom",
"Substance-Related Disorders",
"England"
] | [
"Journal Article"
] | 11 | 5 | 3588 | pmc-id: PMC13426604; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540932/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540920 | 10.23889/ijpds.v11i5.3727 | Large-scale geocoding via iterative deduplication: Building a unified address database in Brazil with CIDACS-RL | This work aims to construct a dataset of unique addresses from Brazilian administrative, socioeconomic, and health databases. We assess the potential of iterative deduplication to generate a parent-duplicate data structure that supports address management and downstream information retrieval tasks. Our approach followe... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Pita R",
"Ichihara M",
"Rocha G",
"Santos C",
"Ribeiro L",
"Pita P",
"Sena S",
"Eustáquio F",
"Gomes J",
"Silva R"
] | Pita R | Silva R | [
"Brazil",
"Humans",
"Databases, Factual",
"Geographic Information Systems",
"Geographic Mapping"
] | [
"Journal Article"
] | 11 | 5 | 3727 | pmc-id: PMC13426779; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540920/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540915 | 10.23889/ijpds.v11i5.3678 | Clean Data, Breakthrough Insights: The Importance of Standardizing Your Research Warehouse | Leveraging routinely collected health services data to conduct scientifically robust research requires a clear understanding and standardization of data from disparate clinical information systems which often change over time. Within Alberta Provincial Research Data Services (PRDS) a large team of analysts utilize a va... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Youngson E",
"Armani N",
"Whitten T",
"Quan H",
"Li B",
"Wang T",
"Bakal J"
] | Youngson E | Bakal J | [
"Humans",
"Alberta",
"Data Warehousing",
"Electronic Health Records",
"Registries"
] | [
"Journal Article"
] | 11 | 5 | 3678 | pmc-id: PMC13426613; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540915/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540912 | 10.23889/ijpds.v11i5.3684 | What is needed to make administrative data 'research ready' for causal inference? A case study of the Education and Child Health Insights from Linked Data (ECHILD) database of 15 million children in England | Many jurisdictions have linked education and health data throughout childhood to address policy questions relating to equity and effectiveness of services. We use the example of special educational needs and disability (SEND) policy to show that causal evidence of effectiveness, based on administrative data, can be lim... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Gilbert R",
"De Stavola B",
"Nguyen V",
"Harron K"
] | Gilbert R | Harron K | [
"Humans",
"England",
"Education, Special",
"Child Health",
"Child",
"Child, Preschool",
"Databases, Factual",
"Cerebral Palsy",
"Causality",
"Cleft Lip",
"Cleft Palate",
"Female",
"Educational Status",
"Male",
"Secondary Data Analysis"
] | [
"Journal Article"
] | 11 | 5 | 3684 | pmc-id: PMC13426612; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540912/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540888 | 10.23889/ijpds.v11i5.3581 | ODISSEI: the Dutch National Infrastructure for Social Science | This presentation demonstrates how the ODISSEI research infrastructure enables interoperable, population-scale social science through the integration of data, compute, and services. At the core of the architecture is access to high-quality administrative microdata via Statistics Netherlands (CBS), combined with secure ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Emery T"
] | Emery T | Emery T | [
"Netherlands",
"Social Sciences",
"Humans",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3581 | pmc-id: PMC13426633; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540888/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540877 | 10.23889/ijpds.v11i5.3739 | Ascertainment of Chronic Kidney Disease and Palliative Care using routine health administrative data consolidated in a Health Information Exchange, Western Cape South Africa | The Provincial Health Data Centre (PHDC) integrates person-level clinical and administrative data in the public health systems, using clinically-informed phenotypic algorithms to infer health conditions (episodes), from laboratory, medication and service-use data. Identifying patients living with CKD and requiring pall... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Phelanyane F",
"Tiffin N",
"Boulle A"
] | Phelanyane F | Boulle A | [
"Humans",
"Palliative Care",
"South Africa",
"Renal Insufficiency, Chronic",
"Female",
"Algorithms",
"Male",
"Health Information Exchange",
"Middle Aged",
"Registries",
"Aged",
"Adult",
"Kidney Failure, Chronic"
] | [
"Journal Article"
] | 11 | 5 | 3739 | pmc-id: PMC13426638; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540877/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540872 | 10.23889/ijpds.v11i5.3683 | Developing an Evaluation Toolkit for Data Linkage Pipelines | The linkage evaluation toolkit project aims to develop tools and criteria that can be used to evaluate data linkage pipelines and methods. This toolkit will not only allow assessment of a single pipeline, but will also facilitate the comparison between pipelines; enabling analysts to identify their strengths and weakne... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Quinn L",
"Seguin M",
"Hanif S",
"White Z"
] | Quinn L | White Z | [
"Humans",
"Information Storage and Retrieval",
"Software"
] | [
"Journal Article"
] | 11 | 5 | 3683 | pmc-id: PMC13426733; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540872/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540860 | 10.23889/ijpds.v11i5.3631 | Investigating Biases in Seniors' Drug Data Coverage in Canada | While no province in Canada covers the cost of prescriptions for all of its residents, all have some form of provincial supplementary coverage (PSC) to cover some costs for particular subgroups (based on age, economics, and/or diagnosis). This PSC data can provide insights into the drug dispensation patterns of the pop... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"A Stewart S",
"Park J",
"von Maltzahn M",
"Black E",
"E Isenor J",
"Sketris I",
"Trenaman S"
] | A Stewart S | Trenaman S | [
"Humans",
"Nova Scotia",
"Female",
"Aged",
"Male",
"Bias",
"Drug Prescriptions",
"Databases, Factual",
"Drug Information Services",
"Aged, 80 and over"
] | [
"Journal Article"
] | 11 | 5 | 3631 | pmc-id: PMC13426606; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540860/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540857 | 10.23889/ijpds.v11i5.3531 | Publishing Linked Data with Correction Weights | Data linkage is often used to make inferences from distinct data sources. The data may be linked by a set of variables with high discrimination, for example, a social security number or some personal information. A good linking variable often implies a high disclosure risk in identifying the corresponding person. To pr... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Liu A",
"Lugtig P",
"Scholtus S",
"de Waal T"
] | Liu A | de Waal T | [
"Humans",
"Information Storage and Retrieval",
"Publishing",
"Bias"
] | [
"Journal Article"
] | 11 | 5 | 3531 | pmc-id: PMC13426566; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540857/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540820 | 10.23889/ijpds.v11i5.3629 | Pilot Samples for Estimation of Linkage Error | Efficient estimation of linkage error in large linked datasets requires careful allocation of limited clerical review resources. We investigate the use of small stratified "pilot" samples as an initial, low-cost strategy for informing sample size calculation and allocation across strata when estimating binomial error p... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Thomson G",
"Wray M"
] | Thomson G | Wray M | [
"Computer Simulation",
"Pilot Projects",
"Sample Size",
"Datasets as Topic"
] | [
"Journal Article"
] | 11 | 5 | 3629 | pmc-id: PMC13426563; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540820/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540817 | 10.23889/ijpds.v11i5.3516 | From Consultation to Innovation: A Data Access Pathways Tool to Navigate Australia's Linked Data Landscape | Australia's administrative data linkage environment has evolved from state-based repositories used for internal reporting, to an ecosystem of national linked data assets alongside bespoke linkage services. This has increased complexity for researchers seeking linked data access. A 2024 national consultation identified ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Dombrovskaya M",
"Hagemann E",
"Flack F"
] | Dombrovskaya M | Flack F | [
"Australia",
"Access to Information",
"Humans",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3516 | pmc-id: PMC13426724; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540817/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540800 | 10.23889/ijpds.v11i5.3732 | Why Big Data Matters - Free schools resource to engage young people in health research | In collaboration with the Schools Health Research Network in Scotland (SHINE), Generation Scotland (GS) developed a free schools resource to educate students about health data and the value of taking part in research, supporting the recruitment of young people to the GS cohort. A scoping exercise with SHINE helped iden... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Robertson S",
"Milbourn H",
"Campbell A",
"Clark F",
"Flaig R",
"Kirby L",
"Xiao X",
"Whalley H",
"Sudlow C"
] | Robertson S | Sudlow C | [
"Humans",
"Scotland",
"Big Data",
"Adolescent",
"Schools",
"Focus Groups"
] | [
"Journal Article"
] | 11 | 5 | 3732 | pmc-id: PMC13426653; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540800/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540798 | 10.23889/ijpds.v11i5.3711 | Strengthening Trusted Research Environment Interoperability: A Metadata Platform Enabling Population-Scale Data Linkage Research | Trusted Research Environments (TREs) increasingly underpin cross-sectoral and population-scale data linkage research, yet no single product currently provides a flexible, interoperable way to store and expose the breadth of a TRE's data assets, let alone in a useful way. Existing systems often lack the adaptability nee... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Bale M",
"Thompson S"
] | Bale M | Thompson S | [
"Metadata",
"Humans",
"Information Storage and Retrieval",
"Databases, Factual",
"Systems Integration"
] | [
"Journal Article"
] | 11 | 5 | 3711 | pmc-id: PMC13426595; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540798/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540796 | 10.23889/ijpds.v11i5.3757 | Enhancing geocoding in Brazil through language model-based preprocessing | Similarity-based geocoding pipelines are highly sensitive to lexical noise in address data. This work evaluates the potential of language models to enhance and standardize address inputs during preprocessing, thereby improving geocoding accuracy in CIDACS-RL, which relies on Jaro-Winkler similarity and is sensitive to ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Pita R",
"Rocha G",
"Ichihara M",
"Harron K",
"Brito P",
"Carreiro R",
"Almeida B",
"Ramos P",
"Barreto M",
"Barreto M"
] | Pita R | Barreto M | [
"Brazil",
"Geographic Mapping",
"Humans",
"Geographic Information Systems",
"Large Language Models"
] | [
"Journal Article"
] | 11 | 5 | 3757 | pmc-id: PMC13426686; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540796/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540782 | 10.23889/ijpds.v11i5.3517 | The automated generation of data linkage Information: A reusable, scalable metadata framework for Trusted Research Environments | Using the correct linkage keys to join tables is essential when combining data from multiple sources. Although Trusted Research Environments (TREs) provide metadata to support data linkage, to the best of our knowledge, none currently automate the creation of detailed table-level linkage information. Researchers often ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Mhereeg M",
"Rawlings A",
"Davies G",
"Howell-Wright O",
"Hughes L",
"Akbari A",
"Evans H"
] | Mhereeg M | Evans H | [
"Metadata",
"Information Storage and Retrieval",
"Algorithms",
"Databases, Factual",
"Humans"
] | [
"Journal Article"
] | 11 | 5 | 3517 | pmc-id: PMC13426578; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540782/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540781 | 10.23889/ijpds.v11i5.3598 | Splink: recent developments and realtime linkage | Splink is the award-winning open-source data-linkage software developed by the UK's Ministry of Justice (MoJ). It implements the probabilistic Fellegi-Sunter model in SQL, allowing users to employ their execution backend of choice, whether that be with DuckDB, Spark, or another engine of preference. Splink's focus on p... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Bond A"
] | Bond A | Bond A | [
"Software",
"Humans",
"United Kingdom",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3598 | pmc-id: PMC13426631; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540781/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540777 | 10.23889/ijpds.v11i5.3550 | The UK Longitudinal Linkage Collaboration: the Trusted Research Environment for data linkage in longitudinal population research | We have created an unprecedented interdisciplinary infrastructure integrating data from UK-wide LPS linked to participants' health (NHS), administrative (DWP, HMRC) and place-based records (e.g. environmental pollutants, proximity to healthy assets). Researchers can apply to access all these data via a single applicati... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Boyd A",
"Flaig R",
"Oakley J",
"Campbell K",
"Evans Stela McLachlan K",
"Thomas Emma Turner R"
] | Boyd A | Thomas Emma Turner R | [
"United Kingdom",
"Longitudinal Studies",
"Humans",
"Information Storage and Retrieval",
"Cooperative Behavior"
] | [
"Journal Article"
] | 11 | 5 | 3550 | pmc-id: PMC13426597; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540777/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540774 | 10.23889/ijpds.v11i5.3658 | Use of data linkage and LEO data in the evaluation of the Basic Income Pilot in Wales | The presentation will outline the data linkage methodology underpinning the evaluation of Wales' Basic Income Pilot (BIP), with a particular focus on connecting BIP participant data to the Longitudinal Education Outcomes (LEO) datasets. The BIP is a landmark pilot providing care-leavers with a monthly income for two ye... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Fallick S",
"Helliwell K"
] | Fallick S | Helliwell K | [
"Wales",
"Humans",
"Pilot Projects",
"Income",
"Information Storage and Retrieval",
"Employment",
"Longitudinal Studies"
] | [
"Journal Article"
] | 11 | 5 | 3658 | pmc-id: PMC13426625; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540774/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540771 | 10.23889/ijpds.v11i5.3620 | Diversity of record pairs and mental models in clerical review: What reviewers use to decide matches | Clerical review is an integral step of many data linkage systems. It employs human expertise to assess record pairs for which a decision model, such as probabilistic record linkage, has not been able to make a match (two records refer to the same individual) or non-match (two records refer to different individuals) dec... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Dharmawimala Y",
"Christen P",
"Ziyad S",
"Lam J",
"Vidanage A",
"Schnell R"
] | Dharmawimala Y | Schnell R | [
"Humans",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3620 | pmc-id: PMC13426657; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540771/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540750 | 10.23889/ijpds.v11i5.3591 | Using mental health and education data for research and policy insights: A ten-year retrospective of a South London data linkage | Since 2015, South London and Maudsley NHS Foundation Trust (London, United Kingdom) has maintained a data linkage between its de-identified Child and Adolescent Mental Health Services records and the Department for Education's National Pupil Database. Most recently refreshed up to the 2023/24 academic year, this linkag... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Wickersham A",
"Downs J"
] | Wickersham A | Downs J | [
"Humans",
"London",
"Mental Health",
"Retrospective Studies",
"Adolescent",
"Child",
"Mental Health Services",
"Health Policy",
"Information Storage and Retrieval"
] | [
"Journal Article"
] | 11 | 5 | 3591 | pmc-id: PMC13426584; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540750/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540745 | 10.23889/ijpds.v11i5.3675 | Harmonised Health Outcomes Across Administrative Data: Lessons, Opportunities, and Challenges from UK Biobank | To develop a resource that maps health outcomes across coding schemas in linked administrative data in UK Biobank, addressing the challenge of identifying equivalent outcomes from multiple sources. UK Biobank is a prospective cohort study of ∼500,000 adults, recruited between 2006-2010, with follow up for health outcom... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Domzaridou E",
"Lacey B",
"Conroy M",
"Allen N",
"Li Nuffield Y"
] | Domzaridou E | Li Nuffield Y | [
"Humans",
"United Kingdom",
"International Classification of Diseases",
"UK Biobank",
"Prospective Studies",
"Clinical Coding",
"Biological Specimen Banks",
"Outcome Assessment, Health Care"
] | [
"Journal Article"
] | 11 | 5 | 3675 | pmc-id: PMC13426564; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540745/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540729 | 10.23889/ijpds.v11i5.3642 | Multiple Sclerosis and ethnicity in Wales: a SAIL Databank study | Multiple Sclerosis (MS) is the commonest non-traumatic cause of disability in younger people. Prevalence of MS by deprivation and ethnicity is rarely reported, as ethnicity is not accurately or consistently recorded in national datasets. Ethnicity data within the Secure Anonymised Information Linkage (SAIL) Databank is... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Witts J",
"Tallantyre E",
"Rodgers J",
"Nicholas R",
"Middleton R"
] | Witts J | Middleton R | [
"Adolescent",
"Adult",
"Aged",
"Female",
"Humans",
"Male",
"Middle Aged",
"Young Adult",
"Databases, Factual",
"Ethnicity",
"Multiple Sclerosis",
"Prevalence",
"Wales",
"Black People",
"Asian People",
"White People"
] | [
"Journal Article"
] | 11 | 5 | 3642 | pmc-id: PMC13426553; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540729/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42540721 | 10.23889/ijpds.v11i5.3738 | From Data Linkage to Simulation: A New Framework for Evaluating Aged Care Policies | The global rise in older populations has profound implications for health and social systems. Governments are investing in policies to support ageing in the community, yet robust evidence of effectiveness is limited. We are conducting population-level comparative effectiveness studies of Australian government policies ... | Int J Popul Data Sci | International journal of population data science | 2026 | 2,026 | [
"Andrew N",
"Collyer T",
"Beare R",
"Carver A",
"Long K",
"Churilov L",
"Ilomäki J",
"Sq Tan G",
"Ung D",
"Kilkenny M",
"Lannin N"
] | Andrew N | Lannin N | [
"Humans",
"Australia",
"Female",
"Health Policy",
"Aged",
"Male",
"Electronic Health Records",
"Computer Simulation",
"Information Storage and Retrieval",
"Health Services for the Aged"
] | [
"Journal Article"
] | 11 | 5 | 3738 | pmc-id: PMC13426582; | 2399-4908 | eng | https://pubmed.ncbi.nlm.nih.gov/42540721/ | rjxlJyWyVQdbk42ae | eECllsEMa92f7cpQM |
42543358 | 10.19540/j.cnki.cjcmm.20260416.302 | [Development and application of multidimensional comprehensive evaluation system for flowability of TCM powders based on principal component analysis] | To address the problem that conventional evaluation methods struggle to comprehensively characterize the complex flow behavior of TCM powders, this study utilized an FT4 powder rheometer to perform a multidimensional characterization of 24 representative samples, including decoction pieces, extracts, excipients, and gr... | Zhongguo Zhong Yao Za Zhi | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2026 Jul | 2,026 | [
"Hu HQ",
"Wan XH",
"Liu Y",
"Hu H",
"Liu YH",
"Li YH",
"Peng CC",
"Wu ZF"
] | Hu HQ | Wu ZF | [
"Powders",
"Drugs, Chinese Herbal",
"Principal Component Analysis",
"Rheology",
"Quality Control",
"Chemistry, Pharmaceutical"
] | [
"English Abstract",
"Journal Article"
] | 51 | 13 | 3687-3696 | null | 1001-5302 | chi | https://pubmed.ncbi.nlm.nih.gov/42543358/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42543351 | 10.19540/j.cnki.cjcmm.20260413.301 | [Crystal form issues and development prospects of TCM solid preparations] | As the dominant dosage form in clinical practice of TCM, solid preparations face core challenges concerning quality stability and consistent therapeutic efficacy. Clinical observations have revealed efficacy variations among different preparation forms of the same TCM or even among products of the same preparation from... | Zhongguo Zhong Yao Za Zhi | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2026 Jul | 2,026 | [
"Hua H",
"Ji YL",
"Ao Z",
"Zhao JN"
] | Hua H | Zhao JN | [
"Drugs, Chinese Herbal",
"Crystallization",
"Quality Control",
"Humans",
"Medicine, Chinese Traditional",
"Chemistry, Pharmaceutical",
"Drug Compounding"
] | [
"Journal Article",
"Review",
"English Abstract"
] | 51 | 13 | 3617-3630 | null | 1001-5302 | chi | https://pubmed.ncbi.nlm.nih.gov/42543351/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42543323 | 10.19540/j.cnki.cjcmm.20260408.302 | [Analysis and reflection on pharmacological effects and novel formulation technologies of lumbrokinase from Pheretima] | Lumbrokinase, a serine protease complex extracted from Pheretima, possesses specific fibrinolytic activity and is clinically used for thrombolytic therapy in cardiovascular and cerebrovascular diseases. Due to its low bleeding risk profile, novel formulation technologies have significantly enhanced its therapeutic effi... | Zhongguo Zhong Yao Za Zhi | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2026 Jul | 2,026 | [
"Luo WY",
"Zhao FY",
"Huang JF",
"Zhang XW",
"Huang XY",
"Fu Y",
"Jiang W",
"Li WS",
"Yue PF"
] | Luo WY | Yue PF | [
"Animals",
"Humans",
"Fibrinolytic Agents",
"Serine Endopeptidases",
"Drug Compounding",
"Chemistry, Pharmaceutical",
"Endopeptidases"
] | [
"Journal Article",
"Review",
"English Abstract"
] | 51 | 14 | 3929-3938 | null | 1001-5302 | chi | https://pubmed.ncbi.nlm.nih.gov/42543323/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42538652 | 10.6002/ect.MESOT2025.L35 | Precision Immunosuppression in Kidney Transplantation: A Comprehensive Review | Individualized immunosuppression represents a paradigm shift in kidney transplant from traditional "trial-and-error" dosing strategies toward individualized regimens. Precision immunosuppression is informed by pharmacogenetics, biomarkers, therapeutic drug monitoring, and recently artificial intelligence-based predicti... | Exp Clin Transplant | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation | 2026 Jul | 2,026 | [
"Argani H"
] | Argani H | Argani H | [
"Humans",
"Kidney Transplantation",
"Immunosuppressive Agents",
"Graft Rejection",
"Graft Survival",
"Treatment Outcome",
"Risk Factors",
"Precision Medicine",
"Predictive Value of Tests",
"Risk Assessment",
"Drug Monitoring",
"Pharmacogenetics",
"Drug Dosage Calculations",
"Biomarkers"
] | [
"Journal Article",
"Review"
] | 24 | Suppl 2 | 20-25 | null | 1304-0855 | eng | https://pubmed.ncbi.nlm.nih.gov/42538652/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42535720 | 10.1002/jcph.70250 | From Small Data to Big Decisions: How Clinical Pharmacology Shapes Rare Disease Development | Rare‑disease drug development is constrained by small and heterogeneous patient populations, limited natural‑history data, and the impracticality of large, randomized trials. Despite increasing regulatory acceptance of totality-of-evidence and mechanism-based development pathways, generating reliable, decision-ready ev... | J Clin Pharmacol | Journal of clinical pharmacology | 2026 Aug | 2,026 | [
"Xu Y",
"Verone-Boyle A",
"Schmitz N",
"Zahir H",
"Willis BA"
] | Xu Y | Willis BA | [
"Humans",
"Rare Diseases",
"Pharmacology, Clinical",
"Drug Development",
"Big Data"
] | [
"Journal Article",
"Review"
] | 66 | 8 | e70250 | pmc-id: PMC13426045; | 0091-2700 | eng | https://pubmed.ncbi.nlm.nih.gov/42535720/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42530141 | 10.1002/jcph.70246 | Innovative Clinical Pharmacology, Modeling, and Simulation Strategies for Accelerating Rare Disease Drug Development | Clinical drug development for rare diseases continues to face significant challenges due to disease heterogeneity, fewer available patients, and incomplete understanding of pathogenesis, resulting in trials with limited clinical data, thus constraining traditional development pathways. Clinical pharmacology, modeling, ... | J Clin Pharmacol | Journal of clinical pharmacology | 2026 Aug | 2,026 | [
"Oberoi RK",
"Peer CJ",
"Tripathi A",
"Mohammad AS",
"Sun Y",
"Der K",
"Song Y",
"Huang J",
"Upreti VV"
] | Oberoi RK | Upreti VV | [
"Humans",
"Rare Diseases",
"Drug Development",
"Pharmacology, Clinical",
"Models, Biological",
"Computer Simulation"
] | [
"Journal Article",
"Review"
] | 66 | 8 | e70246 | pmc-id: PMC13422008; | 0091-2700 | eng | https://pubmed.ncbi.nlm.nih.gov/42530141/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42528013 | 10.1002/psp4.70310 | Sex-Related Differences in Physiologically-Based Biopharmaceutics Modeling | Physiologically based pharmacokinetic (PBPK) and physiologically-based biopharmaceutics (PBBM) modeling are valuable tools in drug development, allowing mechanistic predictions of drug absorption and disposition. However, sex-related differences in gastrointestinal physiology are often underrepresented in virtual popul... | CPT Pharmacometrics Syst Pharmacol | CPT: pharmacometrics & systems pharmacology | 2026 Aug | 2,026 | [
"Chavarría-Rojas M",
"Murshed M",
"Lorier M",
"Fotaki N",
"Ibarra M"
] | Chavarría-Rojas M | Ibarra M | [
"Female",
"Humans",
"Models, Biological",
"Ketoprofen",
"Male",
"Biopharmaceutics",
"Gastrointestinal Tract",
"Sex Factors",
"Sex Characteristics"
] | [
"Journal Article"
] | 15 | 8 | e70310 | null | 2163-8306 | eng | https://pubmed.ncbi.nlm.nih.gov/42528013/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42527723 | 10.1007/s11912-026-01811-5 | The Application and Advancement of Herbal Medicine in Gastrointestinal Cancers: A Bibliometrix Visualization and Pan-cancer Analysis | Herbal medicine has emerged as an important area of investigation in gastrointestinal cancers owing to its multitarget therapeutic potential and growing integration with modern oncology. However, the rapid expansion of the literature has resulted in a fragmented understanding of the field's knowledge structure, researc... | Curr Oncol Rep | Current oncology reports | 2026 Jul 30 | 2,026 | [
"Zhao L",
"Wang H",
"Jiang Y",
"Zhao Z",
"Liang Q",
"Li Y",
"Wang J",
"Zhong W",
"Xu Y",
"Zeng X",
"Liu T",
"Yang Y",
"Wu Q",
"Xu K"
] | Zhao L | Xu K | [
"Humans",
"Gastrointestinal Neoplasms",
"Bibliometrics",
"Herbal Medicine"
] | [
"Journal Article",
"Review"
] | 28 | 1 | null | null | 1523-3790 | eng | https://pubmed.ncbi.nlm.nih.gov/42527723/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42525762 | 10.1126/sciadv.aee8648 | IoT-enabled wireless neural implant for chronic, programmable neuropharmacology and optogenetics | Wireless in vivo neuropharmacology and optogenetics offer a powerful way to link molecular signaling, defined neural populations, and behavior in freely moving animals. However, existing implantable wireless systems developed for this purpose often suffer from imprecise dosing, backflow contamination, and nonrefillable... | Sci Adv | Science advances | 2026 Jul 31 | 2,026 | [
"Jeong EY",
"Park JW",
"Cho S",
"Han D",
"Kim CY",
"Kim SW",
"Lee W",
"Kim WY",
"Kim JH",
"Jeong JW"
] | Jeong EY | Jeong JW | [
"Optogenetics",
"Animals",
"Wireless Technology",
"Neuropharmacology",
"Rats",
"Cocaine",
"Drug Delivery Systems",
"Mice"
] | [
"Journal Article"
] | 12 | 31 | eaee8648 | pmc-id: PMC13418541; | 2375-2548 | eng | https://pubmed.ncbi.nlm.nih.gov/42525762/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42525646 | 10.1371/journal.pone.0354689 | Formulation development of a biphasic release tablet-in-tablet system containing ketorolac tromethamine | Ketorolac tromethamine (KT) is a potent nonsteroidal anti-inflammatory drug (NSAID) used for moderate to severe pain management. Its short elimination half-life necessitates frequent dosing, which can reduce patient compliance. The objective of this study was to formulate, develop, and optimize a novel biphasic-release... | PLoS One | PloS one | 2026 | 2,026 | [
"Zou P",
"Zeng Y",
"Liao XR",
"Xie XY",
"Li YK",
"Ma YH",
"Liu H"
] | Zou P | Liu H | [
"Ketorolac Tromethamine",
"Tablets",
"Delayed-Action Preparations",
"Drug Liberation",
"Chemistry, Pharmaceutical",
"Anti-Inflammatory Agents, Non-Steroidal",
"Kinetics",
"Excipients"
] | [
"Journal Article"
] | 21 | 7 | e0354689 | pmc-id: PMC13421754; | 1932-6203 | eng | https://pubmed.ncbi.nlm.nih.gov/42525646/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42521898 | 10.1208/s12248-026-01265-4 | Assessment of Sorbitol as a Pharmaceutical Excipient in Oral Liquid Pediatric Formulations Submitted to the U.S. FDA | Sorbitol is a commonly used excipient in pediatric oral liquid formulations. Previous research revealed that sorbitol as an excipient can diminish the bioavailability of concomitant drugs. The reported cases and amount of sorbitol in pediatric formulations has not been explored, thus the aims of this study were to (1) ... | AAPS J | The AAPS journal | 2026 Jul 28 | 2,026 | [
"Abulwerdi GA",
"Cote B",
"Abdel-Rahman S",
"Fletcher EP",
"Burckart GJ"
] | Abulwerdi GA | Burckart GJ | [
"Sorbitol",
"Excipients",
"United States",
"Humans",
"United States Food and Drug Administration",
"Administration, Oral",
"Chemistry, Pharmaceutical",
"Child",
"Biological Availability"
] | [
"Journal Article"
] | 28 | 5 | null | null | 1550-7416 | eng | https://pubmed.ncbi.nlm.nih.gov/42521898/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42520812 | null | Development and Optimization of Antioxidant Poly Herbal Peel-off Mask using Doe Based Approach | Antioxidants protect the skin from free radicals, which are associated with signs of aging, pigmentation, and loss of elasticity. Combining antioxidants in cosmetic formulations may provide broader antioxidant potential. This study focuses on the formulation and optimization of a polyherbal antioxidant peel-off mask us... | Int J Pharm Compd | International journal of pharmaceutical compounding | 2026 May-Jun | 2,026 | [
"Ramakrishnan D",
"Mr J",
"Joy J",
"Jojo GM",
"Abbas FS"
] | Ramakrishnan D | Abbas FS | [
"Antioxidants",
"Plant Extracts",
"Animals",
"Drug Compounding",
"Cosmetics",
"Chemistry, Pharmaceutical",
"Skin"
] | [
"Journal Article"
] | 30 | 3 | 237-252 | null | 1092-4221 | eng | https://pubmed.ncbi.nlm.nih.gov/42520812/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42513194 | 10.3390/molecules31142516 | Herbal Medicine Processing By-Products as Bioactive Resources: In Vivo Evidence for Antioxidant, Anti-Inflammatory, and Immunomodulatory Effects | Processing herbal medicine generates substantial quantities of by-products that are discarded as waste. These residues may retain polysaccharides, flavonoids, saponins, terpenoids, and other constituents with pharmacological relevance. This review discusses the bioactive potential of by-products derived from single tra... | Molecules | Molecules (Basel, Switzerland) | 2026 Jul 18 | 2,026 | [
"Hwang JH",
"Jung JH"
] | Hwang JH | Jung JH | [
"Antioxidants",
"Anti-Inflammatory Agents",
"Humans",
"Animals",
"Immunologic Factors",
"Herbal Medicine",
"Immunomodulating Agents",
"Plants, Medicinal"
] | [
"Journal Article",
"Review"
] | 31 | 14 | null | pmc-id: PMC13416048; | 1420-3049 | eng | https://pubmed.ncbi.nlm.nih.gov/42513194/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42513138 | 10.3390/molecules31142454 | Exclusive Feature Papers in Synthetic Medicinal Chemistry | The collection of manuscripts presented in this issue exemplifies the breadth and vitality of contemporary medicinal chemistry, demonstrating how innovative molecular design, sophisticated synthetic methodologies, and biologically driven investigations continue to expand the frontiers of chemical and pharmaceutical sci... | Molecules | Molecules (Basel, Switzerland) | 2026 Jul 14 | 2,026 | [
"Christodoulou MS",
"Athanassopoulos CM"
] | Christodoulou MS | Athanassopoulos CM | [
"Chemistry, Pharmaceutical",
"Chemistry Techniques, Synthetic",
"Humans",
"Drug Design"
] | [
"Editorial",
"Introductory Journal Article"
] | 31 | 14 | null | pmc-id: PMC13414069; | 1420-3049 | eng | https://pubmed.ncbi.nlm.nih.gov/42513138/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42513128 | 10.3390/molecules31142444 | Interpretable Spectral Evidence Learning from Vis/NIR Imaging for Non-Destructive Authentication of Herbal Medicines | Rapid and non-destructive authentication of herbal medicines is important for quality control and market supervision. This study established an interpretable spectral evidence learning framework for visible and near-infrared (Vis/NIR) imaging-based authentication of Codonopsis Radix (CR) and Aurantii Fructus (AF). Comp... | Molecules | Molecules (Basel, Switzerland) | 2026 Jul 12 | 2,026 | [
"Fan Z",
"Ma C",
"Jing S",
"Huang J",
"Zhang M"
] | Fan Z | Zhang M | [
"Spectroscopy, Near-Infrared",
"Herbal Medicine",
"Drugs, Chinese Herbal",
"Support Vector Machine",
"Machine Learning",
"Plants, Medicinal"
] | [
"Journal Article"
] | 31 | 14 | null | pmc-id: PMC13415804; | 1420-3049 | eng | https://pubmed.ncbi.nlm.nih.gov/42513128/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42504089 | 10.1111/cts.70670 | Genetic Landscape of NAT2 in the Moroccan Population: Implications for Isoniazid Pharmacogenetics in Tuberculosis | The NAT2 gene encodes N-acetyltransferase 2, an enzyme critically involved in the biotransformation of numerous xenobiotics and aromatic amines, including isoniazid, a cornerstone drug in tuberculosis therapy. Genetic polymorphisms in NAT2 lead to variable acetylation rates, clinically categorized as poor, intermediate... | Clin Transl Sci | Clinical and translational science | 2026 Aug | 2,026 | [
"Benyahya N",
"El-Hamri MA",
"Lyahyai J",
"Ratbi I",
"Cherkaoui I",
"Rchiad Z",
"Sefiani A"
] | Benyahya N | Sefiani A | [
"Humans",
"Arylamine N-Acetyltransferase",
"Isoniazid",
"Morocco",
"Antitubercular Agents",
"Tuberculosis",
"Female",
"Pharmacogenetics",
"Male",
"Exome Sequencing",
"Phenotype",
"Adult",
"Polymorphism, Single Nucleotide",
"Pharmacogenomic Variants"
] | [
"Journal Article"
] | 19 | 8 | e70670 | pmc-id: PMC13402876; | 1752-8054 | eng | https://pubmed.ncbi.nlm.nih.gov/42504089/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42502143 | 10.1038/s41397-026-00425-1 | Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study | Direct-to-consumer (DTC) pharmacogenomic (PGx) testing is expanding rapidly in the UK, yet no dedicated regulatory framework currently governs these services. Although a 2021 parliamentary inquiry recommended stronger safeguards and clearer technical standards for genomic testing, these proposals have not been applied ... | Pharmacogenomics J | The pharmacogenomics journal | 2026 Jul 25 | 2,026 | [
"Mathieson A",
"Brunton L",
"Gillibrand S",
"Moldovan R",
"McDermott JH"
] | Mathieson A | McDermott JH | [
"Humans",
"United Kingdom",
"Direct-To-Consumer Screening and Testing",
"Pharmacogenomic Testing",
"Public Opinion",
"Focus Groups",
"Female",
"Male",
"Qualitative Research",
"Adult",
"Pharmacogenetics",
"Middle Aged",
"Genetic Testing"
] | [
"Journal Article"
] | 26 | 4 | null | pmc-id: PMC13401518; | 1470-269X | eng | https://pubmed.ncbi.nlm.nih.gov/42502143/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42494268 | 10.3349/ymj.2025.0364 | Pharmacogenetic Risk Factors for Thiopurine-Induced Leukopenia in Patients with Inflammatory Bowel Disease | Thiopurines remain an effective treatment for maintaining remission in inflammatory bowel disease (IBD), yet their use is often limited by thiopurine-induced leukopenia (TIL), a potentially life-threatening adverse effect. We aimed to investigate pharmacogenetic associations with TIL in patients with IBD. We retrospect... | Yonsei Med J | Yonsei medical journal | 2026 Aug | 2,026 | [
"Boo EK",
"Yu J",
"Oh S",
"Cheon JH",
"Kim JH"
] | Boo EK | Kim JH | [
"Humans",
"Leukopenia",
"Inflammatory Bowel Diseases",
"Female",
"Male",
"Risk Factors",
"Pyrophosphatases",
"Retrospective Studies",
"Nudix Hydrolases",
"Adult",
"Pharmacogenetics",
"Interleukin-6",
"Mercaptopurine",
"Middle Aged",
"Azathioprine",
"Genotype",
"Methyltransferases"
] | [
"Journal Article"
] | 67 | 8 | 603-615 | pmc-id: PMC13407061; | 0513-5796 | eng | https://pubmed.ncbi.nlm.nih.gov/42494268/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42494189 | 10.1002/pds.70442 | A Pharmaco-Epidemiological Research Program Leveraging a Nationwide Database of Kidney Transplantation | The pharmaco-epidemiological research program in kidney transplantation (PERP-KT) aims to evaluate, for the principal maintenance immunosuppressive drugs (MISDs): the influence of model-informed precision dosing on graft and patient survival; long-term exposure-effects relationships; and the benefit-harm balance of the... | Pharmacoepidemiol Drug Saf | Pharmacoepidemiology and drug safety | 2026 Aug | 2,026 | [
"Marquet P",
"Humeau A",
"Crépin S",
"Benoist C",
"Couderc S",
"Monchaud C",
"Labriffe M",
"Saint-Marcoux F"
] | Marquet P | Saint-Marcoux F | [
"Kidney Transplantation",
"Humans",
"Databases, Factual",
"Immunosuppressive Agents",
"Pharmacoepidemiology",
"France",
"Graft Survival",
"Female",
"Male",
"Graft Rejection",
"Registries",
"Middle Aged",
"Adult"
] | [
"Journal Article"
] | 35 | 8 | e70442 | pmc-id: PMC13396964; | 1053-8569 | eng | https://pubmed.ncbi.nlm.nih.gov/42494189/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42490492 | 10.1126/science.adx7219 | Late-stage functionalization with strain-release warheads enables tunable covalent inhibition | Covalent inhibition continues to gain momentum as a strategy for selective protein modulation in both therapeutic and chemical biology contexts. Covalent reactive groups (CRGs) typically engage nucleophilic residues such as cysteine, resulting in targeted protein inactivation. However, common electrophiles such as acry... | Science | Science (New York, N.Y.) | 2026 Jul 23 | 2,026 | [
"Shultz ZP",
"Lee-Sam A",
"Chang YP",
"Sun L",
"Grassie D",
"Gabellini A",
"Pedretty K",
"Scattolin T",
"Izumi V",
"Fang B",
"Sansil S",
"Kakumanu R",
"Wojtas L",
"Koomen J",
"Schönbrunn E",
"Monastyrskyi A",
"Duckett D",
"Lopchuk JM"
] | Shultz ZP | Lopchuk JM | [
"Animals",
"Mice",
"Acrylamides",
"Bioisosterism",
"Cysteine",
"Drug Design",
"Proteins",
"Sulfur"
] | [
"Journal Article"
] | 393 | 6809 | 408-416 | null | 0036-8075 | eng | https://pubmed.ncbi.nlm.nih.gov/42490492/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42489300 | 10.36721/PJPS.2026.39.10.295.1 | Formulation and evaluation of sustained-release pitavastatin-loaded chitosan nanoparticles for enhanced anti-hyperlipidemic activity | Pitavastatin (PVN), a BCS class-II drug, exhibits poor aqueous solubility leading to limited oral bioavailability and therapeutic efficacy. This study aimed to enhance the solubility and anti-hyperlipidemic efficacy of Pitavastatin (PVN) by encapsulating it in chitosan-based polymeric nanoparticles. Pitavastatin-loaded... | Pak J Pharm Sci | Pakistan journal of pharmaceutical sciences | 2026 Oct 1 | 2,026 | [
"Arshad A",
"Zaman M",
"Riaz H",
"Haider MS",
"Ishaq W",
"Adnan S",
"Masood Z",
"Ahmed H",
"Ameer N",
"Rahman HMA",
"Waqas M",
"Farooq M"
] | Arshad A | Farooq M | [
"Chitosan",
"Animals",
"Quinolines",
"Nanoparticles",
"Solubility",
"Male",
"Particle Size",
"Delayed-Action Preparations",
"Rats",
"Drug Liberation",
"Drug Carriers",
"Hypolipidemic Agents",
"Hyperlipidemias",
"Intestinal Absorption",
"Chemistry, Pharmaceutical",
"Rats, Wistar",
"Sp... | [
"Journal Article"
] | 39 | 10 | 3186-3196 | null | 1011-601X | eng | https://pubmed.ncbi.nlm.nih.gov/42489300/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42487463 | 10.1021/acs.molpharmaceut.6c00644 | Predicting pHmax and Salt Disproportionation Risk for Basic Drugs | Pharmaceutical salts are commonly used to enhance the bioavailability of poorly water-soluble drugs. The maximum solubility in water and the physical stability of a salt are closely linked to its pHmax, the pH at which both the free form (acid or base) and the salt can coexist. However, several aspects related to pHmax... | Mol Pharm | Molecular pharmaceutics | 2026 Aug 3 | 2,026 | [
"Yao X",
"Yu M",
"Chen F",
"Du S",
"Kallemeyn LC",
"Bergman J",
"Lesslie MW",
"Chen S",
"Sheikh AY"
] | Yao X | Sheikh AY | [
"Hydrogen-Ion Concentration",
"Salts",
"Solubility",
"Pharmaceutical Preparations",
"Drug Stability",
"Bulk Drugs",
"Water",
"Chemistry, Pharmaceutical"
] | [
"Journal Article"
] | 23 | 8 | 4298-4310 | null | 1543-8384 | eng | https://pubmed.ncbi.nlm.nih.gov/42487463/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42487285 | 10.1002/sim.70676 | A Cautionary Note for Plasmode Simulation Studies in the Setting of Causal Inference | Plasmode simulation has become an important tool for evaluating operating characteristics of different statistical methods in complex settings, such as pharmacoepidemiological studies of treatment effectiveness using electronic health records (EHR) data. These studies provide insight into how estimator performance is i... | Stat Med | Statistics in medicine | 2026 Aug | 2,026 | [
"Shaw PA",
"Gruber S",
"Williamson BD",
"Desai R",
"Shortreed SM",
"Krakauer C",
"Nelson JC",
"van der Laan MJ"
] | Shaw PA | van der Laan MJ | [
"Computer Simulation",
"Humans",
"Models, Statistical",
"Electronic Health Records",
"Randomized Controlled Trials as Topic",
"Causality",
"Pharmacoepidemiology",
"Data Interpretation, Statistical",
"Bias",
"Sample Size"
] | [
"Journal Article"
] | 45 | 18-19 | e70676 | pmc-id: PMC13392349; | 0277-6715 | eng | https://pubmed.ncbi.nlm.nih.gov/42487285/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42487275 | 10.1080/10717544.2026.2702143 | Development and in vivo pharmacokinetic evaluation of a phospholipid complex self-nanoemulsifying drug delivery system (PLC-SNEDDS) for enhanced oral bioavailability of cannabidiol | Cannabidiol (CBD) exhibits poor oral bioavailability (approximately 6%) due to low solubility and excessive first-pass metabolism, limiting its therapeutic potential. This study introduces a novel phospholipid complex self-nanoemulsifying drug delivery system (CBD-PLC-SNEDDS) to enhance CBD delivery. CBD-PLC was integr... | Drug Deliv | Drug delivery | 2026 Dec 31 | 2,026 | [
"Muta T",
"Mukhopadhyay S",
"Noll B",
"Song Y",
"Garg S"
] | Muta T | Garg S | [
"Cannabidiol",
"Animals",
"Biological Availability",
"Phospholipids",
"Administration, Oral",
"Emulsions",
"Rats, Sprague-Dawley",
"Rats",
"Particle Size",
"Male",
"Drug Delivery Systems",
"Solubility",
"Nanoparticles",
"Nanoparticle Drug Delivery System",
"Drug Stability",
"Chemistry,... | [
"Journal Article"
] | 33 | 1 | 2702143 | pmc-id: PMC13398106; | 1071-7544 | eng | https://pubmed.ncbi.nlm.nih.gov/42487275/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42475378 | 10.1097/PRA.0000000000000936 | Developments in Clinical Psychopharmacology From 2000 Through 2026: A Personal Perspective | The first column in this 2-part series covered the history of clinical psychopharmacology from the author's perspective from 1975 to 2000. This column covers the last 26 years of clinical psychopharmacology as experienced by the author from 2000 to 2026. It focuses on the following major areas: (1) system-level neurobi... | J Psychiatr Pract | Journal of psychiatric practice | 2026 Jul 1 | 2,026 | [
"Preskorn SH"
] | Preskorn SH | Preskorn SH | [
"Humans",
"Psychopharmacology",
"History, 20th Century",
"History, 21st Century",
"Psychotropic Drugs",
"Antidepressive Agents",
"Drug Monitoring",
"Drug Discovery",
"Mental Disorders"
] | [
"Journal Article",
"Historical Article",
"Review"
] | 32 | 4 | 196-202 | null | 1527-4160 | eng | https://pubmed.ncbi.nlm.nih.gov/42475378/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42470382 | 10.1021/acs.molpharmaceut.6c00558 | Safety of Pharmaceutical Nanosuspensions in Drug Delivery: Evidence, Knowledge Gaps, and Safety-By-Design Strategies | Poor aqueous solubility remains a major barrier to small-molecule drug development. Pharmaceutical nanosuspensions, composed mainly of drug nanocrystals stabilized by small amounts of excipients, can improve dissolution and have been translated into several oral products and long-acting injectables. However, their simp... | Mol Pharm | Molecular pharmaceutics | 2026 Aug 3 | 2,026 | [
"Ma Y",
"Wang L",
"Wang Y"
] | Ma Y | Wang Y | [
"Humans",
"Nanoparticles",
"Suspensions",
"Animals",
"Solubility",
"Drug Delivery Systems",
"Particle Size",
"Excipients",
"Administration, Oral",
"Chemistry, Pharmaceutical",
"Drug Compounding",
"Tissue Distribution",
"Drug Stability"
] | [
"Journal Article",
"Review"
] | 23 | 8 | 4003-4024 | null | 1543-8384 | eng | https://pubmed.ncbi.nlm.nih.gov/42470382/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42467807 | null | Selected highlights from the 26th International Workshop on Clinical Pharmacology of HIV, Hepatitis, and Other Antiviral Drugs | Clinical pharmacology plays a crucial role in the successful treatment and prevention of HIV and other viral infections. Information from the field of clinical pharmacology leads to the development of novel antiviral treatments, supports the evaluation of efficacy and safety of antiviral therapies, informs the manageme... | Top Antivir Med | Topics in antiviral medicine | 2026 Jul 16 | 2,026 | [
"Scarsi KK",
"Marzolini C",
"Marra F",
"Tseng AL"
] | Scarsi KK | Tseng AL | [
"Humans",
"Antiviral Agents",
"HIV Infections",
"Pharmacology, Clinical",
"Drug Interactions",
"Hepatitis, Viral, Human"
] | [
"Review",
"Journal Article"
] | 34 | 3 | 545-553 | pmc-id: PMC13422888; | 2161-5861 | eng | https://pubmed.ncbi.nlm.nih.gov/42467807/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42454740 | 10.1080/10717544.2026.2702133 | Phytotherapeutics self-microemulsifying systems in pellet dosage form for enhanced intestinal drug delivery: formulation, stability, and in-vivo performance | Self-microemulsifying drug delivery systems (SMEDDS) containing volatile phytotherapeutics such as thymol (T), carvacrol (C), and eugenol (E) present significant formulation challenges, even when solidified. Their instability and interactions with coatings often hinder intestinal delivery. To address these limitations,... | Drug Deliv | Drug delivery | 2026 Dec 31 | 2,026 | [
"Koutná G",
"Kotouček J",
"Macků J",
"Kubová K",
"Urbanová M",
"Janisová L",
"Šeděnková I",
"Muselík J",
"Vysloužil J",
"Mašek J",
"Mašková E",
"Pavelková M",
"Vetchý D",
"Brus J"
] | Koutná G | Brus J | [
"Animals",
"Drug Delivery Systems",
"Emulsions",
"Solubility",
"Intestinal Absorption",
"Particle Size",
"Drug Stability",
"Chemistry, Pharmaceutical",
"Excipients",
"Swine",
"Administration, Oral"
] | [
"Journal Article"
] | 33 | 1 | 2702133 | pmc-id: PMC13374766; | 1071-7544 | eng | https://pubmed.ncbi.nlm.nih.gov/42454740/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42453019 | 10.2174/0118715265376840250717072610 | Optimizing Chitosan-based Posaconazole Dry Powder Formulation Using Box-Behnken Design: The Role of Leucine in Enhancing Performance | The objective of this study was to develop and optimize a dry powder inhalation formulation of Posaconazole-loaded Chitosan Nanoparticles (POS-CSNPs) using a Quality by Design (QbD) approach. The aim was to enhance pulmonary drug delivery and antifungal efficacy, particularly against Rhizopus oryzae, by improving drug ... | Infect Disord Drug Targets | Infectious disorders drug targets | 2026 | 2,026 | [
"Singh SK",
"Pancholi SS"
] | Singh SK | Pancholi SS | [
"Chitosan",
"Antifungal Agents",
"Triazoles",
"Leucine",
"Particle Size",
"Nanoparticles",
"Drug Compounding",
"Rhizopus oryzae",
"Administration, Inhalation",
"Drug Liberation",
"Powders",
"Chemistry, Pharmaceutical",
"Excipients",
"Dry Powder Inhalers",
"Drug Carriers"
] | [
"Journal Article"
] | 26 | 3 | 33 | null | 1871-5265 | eng | https://pubmed.ncbi.nlm.nih.gov/42453019/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42450185 | 10.3390/ijms27135916 | Evaluating AI-Generated Molecules for Drug Discovery: From Generic Metrics to Translational Readiness | Artificial intelligence-driven molecular generation has become an increasingly used computational approach for proposing candidate chemical structures in early-stage drug discovery, yet the practical value of the molecules produced is often difficult to judge. Many studies still rely mainly on model-level metrics such ... | Int J Mol Sci | International journal of molecular sciences | 2026 Jun 30 | 2,026 | [
"Liu X",
"Liu H"
] | Liu X | Liu H | [
"Drug Discovery",
"Artificial Intelligence",
"Generative Artificial Intelligence",
"Humans",
"Chemistry, Pharmaceutical"
] | [
"Journal Article",
"Review"
] | 27 | 13 | null | pmc-id: PMC13362286; | 1422-0067 | eng | https://pubmed.ncbi.nlm.nih.gov/42450185/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42446694 | 10.1007/s00044-025-03514-1 | Direct targeting of GLUT1 in cancer: A decade of inhibitor discovery and medicinal chemistry insights | Glucose transporter 1 (GLUT1), the most extensively distributed member of the glucose transporter protein family, plays a pivotal role in regulating glucose metabolism and is indispensable for cellular growth, proliferation, and differentiation. Various metabolic disorders arise from the dysregulation of GLUT1 expressi... | Med Chem Res | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents | 2026 Feb | 2,026 | [
"Meng Z",
"Tian E",
"Hu W",
"Ren C",
"Li J"
] | Meng Z | Li J | [
"Humans",
"Glucose Transporter Type 1",
"Neoplasms",
"Antineoplastic Agents",
"Drug Discovery",
"Animals",
"Chemistry, Pharmaceutical"
] | [
"Journal Article",
"Review"
] | 35 | 2 | 316-339 | null | 1054-2523 | eng | https://pubmed.ncbi.nlm.nih.gov/42446694/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42446683 | 10.1007/s00044-026-03567-w | Piperazine derivatives as anticancer agents: a medicinal chemistry review of structure, mechanism, and clinical translation | Piperazine has become essential for designing anticancer drugs because of its basicity, conformational flexibility, and capacity to serve as a solubilizing agent and molecular linker between hybrid pharmacophores. Researchers have found piperazine to function as a medicinal chemistry component that helps develop bioact... | Med Chem Res | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents | 2026 Jun | 2,026 | [
"Porwal T",
"Kumar R",
"Tripathi S",
"Salahuddin"
] | Porwal T | Salahuddin | [
"Humans",
"Antineoplastic Agents",
"Structure-Activity Relationship",
"Piperazines",
"Neoplasms",
"Chemistry, Pharmaceutical",
"Piperazine"
] | [
"Journal Article",
"Review"
] | 35 | 6 | 1031-1063 | null | 1054-2523 | eng | https://pubmed.ncbi.nlm.nih.gov/42446683/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42446547 | 10.1007/s00044-026-03588-5 | Pyridine-containing antitumor agents: structure-oriented medicinal chemistry, structure-activity relationships, and ADMET liabilities | Pyridine is a common nitrogen-containing heteroaromatic motif in antitumor medicinal chemistry, but its design value is highly context dependent. Here, we synthesize structure-oriented medicinal chemistry principles that govern the use of pyridine-related motifs in antitumor drug design. We discuss pyridine-containing ... | Med Chem Res | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents | 2026 Jul | 2,026 | [
"Zhao W",
"Bie B",
"Wang J",
"Liu X",
"Fang H",
"Niu R"
] | Zhao W | Niu R | [
"Pyridines",
"Humans",
"Structure-Activity Relationship",
"Antineoplastic Agents",
"Chemistry, Pharmaceutical",
"Animals",
"Drug Design"
] | [
"Journal Article",
"Review"
] | 35 | 7 | 1316-1329 | pmc-id: PMC13385078; | 1054-2523 | eng | https://pubmed.ncbi.nlm.nih.gov/42446547/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42444709 | 10.1155/humu/9614566 | Development of a New Portable Genetic Analyzer for Point-of-Care Molecular Genetics and Pharmacogenomics Analysis | Traditional medicine is now moving from the "one-size-fits-all" model toward personalized medicine, where diagnostic and therapeutic decisions are guided by the patient's unique genetic profile. Recent advances in genomics and pharmacogenomics have facilitated the identification of genetic variants linked to disease su... | Hum Mutat | Human mutation | 2026 | 2,026 | [
"Poulida I",
"Karamperis K",
"Routsi IK",
"Sarris I",
"Mantzouranis G",
"Kostopoulos V",
"Mitropoulou C",
"Patrinos GP"
] | Poulida I | Patrinos GP | [
"Humans",
"Point-of-Care Systems",
"Cytochrome P-450 CYP2C19",
"Pharmacogenetics",
"Precision Medicine",
"Genotype",
"Genetic Testing",
"Rapid Diagnostic Tests"
] | [
"Journal Article"
] | 2026 | null | 9614566 | pmc-id: PMC13357681; | 1059-7794 | eng | https://pubmed.ncbi.nlm.nih.gov/42444709/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42444462 | 10.19191/EP26.3.A992.059 | [Comparing synthetic data generation methods in pharmacoepidemiology: reconciling reproducibility with privacy protection] | the use of real-world (RW) data has become an integral part of pharmacoepidemiological research and regulatory assessment. However, access to individual-level data, especially for purposes other than the original ones (secondary use), is often restricted by legal and ethical constraints related to privacy protection. I... | Epidemiol Prev | Epidemiologia e prevenzione | 2026 May-Jun | 2,026 | [
"Mayer F",
"Fazio ML",
"Cutillo M",
"Stendardo G",
"Spila Alegiani S",
"Trifirò G",
"Massari M"
] | Mayer F | Massari M | [
"Humans",
"Generative Adversarial Networks",
"Pharmacoepidemiology",
"Reproducibility of Results",
"Privacy",
"Confidentiality",
"Italy"
] | [
"Journal Article",
"Comparative Study",
"English Abstract"
] | 50 | 3 | 279-289 | null | 1120-9763 | ita | https://pubmed.ncbi.nlm.nih.gov/42444462/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42434809 | 10.1155/bmri/4575160 | Carboxymethylation and Evaluation of Cassava (Manihot esculenta) Starch as a Potential Super-Disintegrant in Tablet Formulations | Cassava (Manihot esculenta) is a significant source of starch in Ethiopia, with potential pharmaceutical applications. However, native starches often require modifications to enhance their utility, particularly as disintegrants. Carboxymethylation is a well-known modification that improves swelling and disintegration c... | Biomed Res Int | BioMed research international | 2026 | 2,026 | [
"Abraha T",
"Molla F",
"Teklebrhan A",
"Hussen H",
"Getachew A"
] | Abraha T | Getachew A | [
"Starch",
"Manihot",
"Tablets",
"Solubility",
"Viscosity",
"Spectroscopy, Fourier Transform Infrared",
"Drug Compounding",
"Excipients",
"Chemistry, Pharmaceutical"
] | [
"Journal Article"
] | 2026 | 1 | e4575160 | pmc-id: PMC13355292; | 2314-6133 | eng | https://pubmed.ncbi.nlm.nih.gov/42434809/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42432825 | 10.1002/pds.70420 | How Negative Controls Are Used in Pharmacoepidemiology: A Methodological Scoping Review of Real-World Observational Studies of Glucagon-Like Peptide-1 Receptor Agonists | Negative controls (NCs) are increasingly used in real-world observational studies to detect residual confounding and systematic bias, but their implementation and reporting remain heterogeneous in applied pharmacoepidemiology. We conducted a methodological scoping review to characterize how NCs were selected, implement... | Pharmacoepidemiol Drug Saf | Pharmacoepidemiology and drug safety | 2026 Jul | 2,026 | [
"Li Z",
"Huang Y",
"Chen H",
"Li J"
] | Li Z | Li J | [
"Glucagon-Like Peptide-1 Receptor Agonists",
"Pharmacoepidemiology",
"Humans",
"Observational Studies as Topic",
"Hypoglycemic Agents",
"Bias",
"Confounding Factors, Epidemiologic",
"Research Design"
] | [
"Journal Article",
"Scoping Review"
] | 35 | 7 | e70420 | pmc-id: PMC13354716; | 1053-8569 | eng | https://pubmed.ncbi.nlm.nih.gov/42432825/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42432465 | 10.1002/cmdc.70361 | Medicinal Chemistry of Agents for Cancer Therapy and Diagnosis From Uruguay | This review summarizes the evolution of our research on anticancer agents, from early efforts on hypoxia-selective cytotoxins to more recent developments in chemoprevention, molecular targeting, and radiopharmacy. Initial studies focused on the design of N-oxide-containing heterocycles as bioreductive-prodrugs activate... | ChemMedChem | ChemMedChem | 2026 Jul 14 | 2,026 | [
"Lavaggi ML",
"García MF",
"Cabrera M",
"Couto M",
"Cerecetto H"
] | Lavaggi ML | Cerecetto H | [
"Humans",
"Antineoplastic Agents",
"Neoplasms",
"Animals",
"Chemistry, Pharmaceutical"
] | [
"Journal Article",
"Review"
] | 21 | 13 | e70361 | pmc-id: PMC13354720; | 1860-7179 | eng | https://pubmed.ncbi.nlm.nih.gov/42432465/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42431828 | 10.1021/acs.jmedchem.5c03492 | Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates | Since its introduction in 1951, bioisosterism has become a cornerstone strategy in drug design and development, enabling chemists to rationally modify molecular structures to optimize biological and physicochemical properties. In this perspective, we examine 57 FDA-approved drugs and 18 advanced drug candidates wherein... | J Med Chem | Journal of medicinal chemistry | 2026 Jul 23 | 2,026 | [
"Wu YJ",
"Chmiel AF",
"Bronson JJ"
] | Wu YJ | Bronson JJ | [
"Bioisosterism",
"Humans",
"Drug Design",
"United States Food and Drug Administration",
"Drug Discovery",
"Drug Approval",
"United States",
"Animals",
"Pharmaceutical Preparations"
] | [
"Journal Article",
"Review"
] | 69 | 14 | 16143-16208 | null | 0022-2623 | eng | https://pubmed.ncbi.nlm.nih.gov/42431828/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42425067 | 10.1021/acs.jmedchem.6c01038 | Retrospective Analysis of the Impact of the "Escape from Flatland" Publication on the Merck & Co., Inc., Small Molecule Portfolio | Sixteen years ago, the fraction of sp3 centers (Fsp3) in a molecule was correlated with clinical progression, solubility, and promiscuity in Lovering's "Escape from Flatland" papers. These trends captivated academia and industry alike, motivating a flurry of strategies to incorporate sp3 carbons into targets for medici... | J Med Chem | Journal of medicinal chemistry | 2026 Jul 23 | 2,026 | [
"Garry OL",
"Cheng AC",
"Northrup AB",
"Merchant RR",
"Yeung CS"
] | Garry OL | Yeung CS | [
"Humans",
"Small Molecule Libraries",
"Solubility",
"Drug Industry",
"Drug Discovery",
"Chemistry, Pharmaceutical"
] | [
"Journal Article",
"Review"
] | 69 | 14 | 16279-16287 | null | 0022-2623 | eng | https://pubmed.ncbi.nlm.nih.gov/42425067/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42421289 | 10.12659/MSM.952296 | Preliminary Application of Antihypertensive Gene Detection in the Treatment of Hypertension | BACKGROUND Hypertension management is often suboptimal due to interindividual variability in drug response. Pharmacogenomics testing may guide personalized therapy by identifying genetic polymorphisms affecting drug efficacy and safety. This study aimed to evaluate whether pharmacogenomics-guided therapy improves blood... | Med Sci Monit | Medical science monitor : international medical journal of experimental and clinical research | 2026 Jul 9 | 2,026 | [
"Xie D",
"Deng M",
"Yang X",
"Huang J",
"Hong X",
"Xu N"
] | Xie D | Xu N | [
"Humans",
"Hypertension",
"Antihypertensive Agents",
"Female",
"Blood Pressure",
"Male",
"Middle Aged",
"Prospective Studies",
"Pharmacogenetics",
"Pharmacogenomic Testing",
"Treatment Outcome",
"Aged",
"Precision Medicine"
] | [
"Journal Article",
"Randomized Controlled Trial"
] | 32 | null | e952296 | pmc-id: PMC13367096; | 1234-1010 | eng | https://pubmed.ncbi.nlm.nih.gov/42421289/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42414738 | 10.1208/s12249-026-03488-2 | A Review on Modular Peptide Anchoring Strategies for Functionalizing Liposomal Nanocarriers: Advancing Non-covalent Design Toward Targeted Cancer Therapy | Targeted drug delivery systems play a crucial role in improving the effectiveness and precision of cancer treatments. Liposomes have been widely investigated as drug carriers due to their versatility. Traditional methods for functionalizing liposomes involve covalent bonding of targeting ligands, which, while effective... | AAPS PharmSciTech | AAPS PharmSciTech | 2026 Jul 7 | 2,026 | [
"Maikifi AS",
"Boonkanokwong V"
] | Maikifi AS | Boonkanokwong V | [
"Liposomes",
"Humans",
"Peptides",
"Neoplasms",
"Drug Carriers",
"Nanoparticles",
"Drug Delivery Systems",
"Antineoplastic Agents",
"Hydrophobic and Hydrophilic Interactions",
"Animals",
"Chemistry, Pharmaceutical"
] | [
"Journal Article",
"Review"
] | 27 | 5 | null | null | 1530-9932 | eng | https://pubmed.ncbi.nlm.nih.gov/42414738/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42414242 | 10.1002/cmdc.70350 | Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands | The imidazoline receptor (IR) system, comprising the I1R, I2R, and I3R subtypes, consists of binding sites involved in cardiovascular, metabolic, and neurological disorders. This review updates the 2004 compilation by Dardonville and Rozas on IR ligands, emphasizing promising ligands, subtype selectivity, and pharmacol... | ChemMedChem | ChemMedChem | 2026 Jul 14 | 2,026 | [
"Kouridaki ME",
"Pallàs M",
"Escolano C"
] | Kouridaki ME | Escolano C | [
"Imidazoline Receptors",
"Humans",
"Ligands",
"Animals",
"Neuroprotective Agents",
"Chemistry, Pharmaceutical",
"Analgesics"
] | [
"Journal Article",
"Review"
] | 21 | 13 | e70350 | pmc-id: PMC13342470; | 1860-7179 | eng | https://pubmed.ncbi.nlm.nih.gov/42414242/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
42413884 | 10.1016/j.ejpb.2026.115179 | Ageing-driven gastrointestinal variability in Parkinson's disease: implications for oral levodopa pharmacokinetics and formulation design | Parkinson's disease is a distinctly age-associated neurodegenerative disorder in which oral levodopa remains the therapeutic foundation, particularly in older adults. Yet with advancing age, the reliability of oral therapy progressively declines not simply due to inadequate dosing, but because ageing reshapes the gastr... | Eur J Pharm Biopharm | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V | 2026 Sep | 2,026 | [
"Madny MA",
"Yadav KS"
] | Madny MA | Yadav KS | [
"Humans",
"Levodopa",
"Parkinson Disease",
"Aging",
"Administration, Oral",
"Antiparkinson Agents",
"Gastrointestinal Tract",
"Animals",
"Intestinal Absorption",
"Biological Availability",
"Chemistry, Pharmaceutical",
"Drug Compounding"
] | [
"Journal Article",
"Review"
] | 226 | null | 115179 | null | 0939-6411 | eng | https://pubmed.ncbi.nlm.nih.gov/42413884/ | UjoTgZKqkiah7PEEk | sMHJETYjjnZkPtPfs |
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