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167,319 | All participants completed questionnaires to capture demographic data, psychiatric and somatic pre-existing conditions, age, gender and level of education. In addition, the Childhood Trauma Questionnaire (CTQ) was used to determine early-life traumatization. The CTQ is one of the most commonly-used and well-validated m... | 3 | 0biomedical | 0Study | [
"Psychiatry"
] |
145,281 | Such variants of concern (VOCs) have repeatedly emerged and progressed rapidly from causing only a small percentage of infections to being the dominant circulating virus variant (19). During the current pandemic, processes of that kind have been observed with alpha (B.1.1.7), beta (B.1.351), and delta variants (B.1.617... | 4 | 0biomedical | 0Study | [
"Virology"
] |
77,424 | Study design and screening process. We carried out two steps of screening tests for candidate allograft donors. Among the 282 candidate surgical donors, 32 donors (11.3 %) were positive for HTLV-1 antibody. We used the femoral heads from seropositive candidates in the present study. HBV, hepatitis B virus; HCV, hepatit... | 3 | 0biomedical | 0Study | [
"Virology",
"Transplantation Medicine"
] |
26,324 | Protein isolation was carried out in three steps. The crude venom of B. moojeni (200 mg) was dissolved in 2.0 mL of 0.05 M ammonium bicarbonate buffer (pH 7.8) and clarified by centrifugation at 10,000 ×g for 10 min. The supernatant was applied to a DEAE-Sephacel column (2.5 × 20 cm) previously equilibrated with 0.05 M... | 5 | 0biomedical | 0Study | [
"Biochemistry"
] |
327,281 | Patients with IA at physical examination had a higher mean total HAQ score than patients without IA in the derivation cohort (0.84 (95% CI 0.77 to 0.89) compared with 0.73 (0.67 to 0.77), p=0.003), indicating a higher degree of functional disability. A gradual increase of the probability of IA at joint examination was ... | 4 | 0biomedical | 0Study | [
"Rheumatology"
] |
260,233 | Ionome phenotyping of the OMON-GAI panel for 23 elements was performed using grain from the 2017 and 2018 seasons. The objective of the study was to evaluate the variation of macro- and microelements, and trace metals in the different groups of genetic resources, identify the relationship between the agronomic and qual... | 4 | 0biomedical | 0Study | [
"Plant Biology",
"Nutrition"
] |
384,386 | Regarding already reported examples, proteins and MSNs can be combined via either surface deposition—grafted or not—or loading into enlarged pores, although those are not the only options. One such exception was the contribution by Lim et al. who delivered immunoglobulin (IgG) to HeLa cells employing a very special sil... | 4 | 0biomedical | 0Study | [
"Nanomedicine",
"Immunology"
] |
164,452 | To Explore the Perforators and their Main Vascular Pedicle. According to the design, the lateral margin and part of the upper margin of the flap were incised down through the skin and subcutaneous tissue to the deep fascia over the VL. The flap was turned inward in the subfascial plane for the identification of perfora... | 4 | 0biomedical | 0Study | [
"Surgery"
] |
174,800 | 6. PLOS requires an ORCID iD for the corresponding author in Editorial Manager on papers submitted after December 6th, 2016. Please ensure that you have an ORCID iD and that it is validated in Editorial Manager. To do this, go to ‘Update my Information’ (in the upper left-hand corner of the main menu), and click on the... | 1 | 2other | 1Other | [
"Publishing"
] |
73,261 | To overcome these limitations and enhance sensitivity, a nanostructure optical biosensor was proposed. As described above, the nanostructure-based sensor has many advantages compared to other sensors. Its relatively large surface area and aspect ratio provide large binding sites. Yeom et al. reported an anodic aluminu... | 4 | 0biomedical | 0Study | [
"Other"
] |
8,208 | At the intervention session, the CANTAB SWM task with high levels of difficulty (up to 12 boxes) and the PAL test with high levels of difficulty (up to 12 shapes) were administered. One Touch Stockings (OTS), a challenging planning task, was selected instead of the easier planning task, the SOC. Those versions of the t... | 3 | 0biomedical | 0Study | [
"Cognitive Psychology",
"Neuroscience"
] |
310,792 | To analyse the sensitivity of the results to changes in any of the three parameters, we sampled additional results centred on the reference, where we only varied one of the three parameters, while leaving the other two at the values of the reference. For the Gaussian variance and the NCC threshold, the same range was u... | 4 | 0biomedical | 0Study | [
"Biostatistics"
] |
59,310 | Eukaryotic cells are compartmentalized into organelles, which fulfil specialized functions. Exchange of substances between these membrane compartments is mediated by vesicular transport1. In this context, the endocytic compartment plays a central role in the sorting of cargo between the plasma membrane, the Golgi appar... | 4 | 0biomedical | 0Study | [
"Cell Biology"
] |
56,628 | The BasicNeeds-GHS partnership (Table 5) was initiated in Northern Ghana by the former in 2002, following a baseline study, which revealed that existing government psychiatric units when compared with facilities in this country’s southern sector lacked the requisite personnel and logistics for handling an increasing bu... | 2 | 2other | 1Other | [
"Psychiatry"
] |
390,651 | Comparing cell proliferation rates and patterns to an observed phenotypic variation is a valuable approach for investigating heterochronic shifts in growth and resulting morphological evolution. Quantitative maps of proliferation during development show how craniofacial growth occurs at stereotypical locations in the c... | 4 | 0biomedical | 0Study | [
"Developmental Biology"
] |
246,042 | Male or female aged 20 or older at the time of consentPatients with hepatobiliary disease and will be undergoing hepatectomyLaparotomic or laparoscopic hepatectomyAny extent of liver resectionAny hepatobiliary disease (including hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and metastatic liver cancer)3.Pa... | 3 | 0biomedical | 1Other | [
"Hepatology",
"Surgical Oncology"
] |
236,100 | To evaluate the curve association of diet quality and frailty prevalence, we used a restricted cubic spline model considering three data points (5th, 50th, and 95th percentiles), based on the distribution of the recommended adherence score. Because the data were sparse, we truncated the analysis at 29 points (1% of the... | 4 | 0biomedical | 0Study | [
"Epidemiology"
] |
141,028 | In addition, the learners need to be motivated enough to control their cognitive processes, performance, and behavioral responses to the classroom demands. To enhance motivation, cognitive processes, psychological wellbeing, and behavioral control, individuals must be self-regulators (Duru et al., 2014). Indeed, the ot... | 4 | 2other | 2Review | [
"Educational Psychology"
] |
160,888 | Figure 11 shows TACs in relevant organs for [11C]MTO and [18F]CETO. In Figure 10A, the [11C]MTO uptake in the adrenal glands showed a negative slope at the end of the experiment. By contrast, in Figure 11B, the corresponding curves for the [18F]CETO uptake show that the accumulation in the adrenal glands was still incr... | 5 | 0biomedical | 0Study | [
"Pharmacokinetics",
"Imaging"
] |
88,224 | Damage in the collagen fibers (a) and damage in the matrix (proteoglycan) (b) when compressing the tissue to \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt}... | 3 | 0biomedical | 0Study | [
"Biomechanics"
] |
94,405 | HIV-1 packages two copies of its RNA genome into each virion . These genomes are non-covalently linked via a process known as genomic RNA dimerization . The initial interaction between the two genomes occurs in a region called the dimer linkage structure present in the 5′ UTR, also known as stem-loop 1 (SL1) . The dime... | 5 | 0biomedical | 0Study | [
"Virology"
] |
209,886 | We found that 6/37 (16.2%) RA subjects had serum anti-PAD4 IgG, and 2 of those 6 subjects (33.3%) possessed the PAD3/4 antibody subset in the serum (Fig. 1 and Table 1). In addition, we found anti-PAD4 IgG in the sputum of 3/37 (8.1%) RA subjects, and 1 of those 3 (33.3%) had sputum anti-PAD3/4 antibodies. In the subse... | 4 | 0biomedical | 0Study | [
"Immunology",
"Rheumatology"
] |
182,740 | To induce SLE, pristane was injected to the mice. After 8 months, the non-injected TG mice showed spontaneous inflammation. WT and TG mice both showed lipogranuloma, a chronic inflammatory response to pristane14, on the diaphragm (Fig. 3a). CTSS was increased in the spleen and sera of TG mice and so does the pristane-i... | 4 | 0biomedical | 0Study | [
"Immunology"
] |
338,440 | The recorded microphone signals were preamplified (Behringer ADA8200, Music Tribe Holding, Makati City, Philippines) and transmitted to a personal computer via an audio interface (MOTU 16 A, Motu, Cambridge, USA). The resulting .wav files were synchronously sampled at 44.1 kHz with an audio bit depth of 32 bit. | 2 | 2other | 1Other | [
"Other"
] |
57,163 | This pattern is consistent with an assembly of bacterial communities of cryoconite holes due to species sorting . Indeed, environmental conditions of cryconite holes strongly differ from those of the ice-marginal environments for temperature, solar irradiation and the presence of water that may favour typical freshwate... | 4 | 0biomedical | 0Study | [
"Microbiology"
] |
240,725 | Our study is subject to several limitations. In the earlier cohort, data were retrospectively collected in contrast with the more recent prospective NCR-BlaZIB cohort. Despite the high number of RCs, the group of patients with (near) complete downstaging and the presence of LNM remained low. Also, information on neoadj... | 4 | 0biomedical | 0Study | [
"Urology",
"Oncology"
] |
157,293 | The PCR amplification reaction was performed in a Bio-Rad thermal cycler with an initial denaturation of 4 min at 95 °C, followed by 30 cycles at 95 °C for 30 s, 55 °C for 30 s, and 72 °C for 1 min, while a final extension was conducted at 72 °C for 10 min. The PCR products were analyzed on 1.5% agarose gels containing... | 4 | 0biomedical | 0Study | [
"Molecular Biology"
] |
208,612 | In accordance with the pooled estimation of the accuracy of IHDS for detecting the cognitive impairment in different groups, including HAND, symptomatic HAND, and HAD, we propose a cut-off score of 10 as a common threshold for all the groups. Assuming a score of 10 as the common threshold, the accuracy measures would b... | 5 | 0biomedical | 0Study | [
"Neurology",
"Neuropsychology"
] |
179,418 | In recent years, Acly arose as a potential metabolic target in combating inflammatory disorders (7, 8, 11, 12). In this study, we demonstrated that Acly-deficient BMDMs have a hyperinflammatory gene signature when activated with LPS in vitro. Apart from increased splenic Il6 expression, other systemic or local inflamma... | 4 | 0biomedical | 0Study | [
"Immunology"
] |
368,475 | The most robust association evidenced in our study is the one between ALS and raw water use, which is expected to be higher in rural areas and small municipalities (Table 3). Recently, Filippini et al. in a study conducted in Italy on 95 cases and 135 controls, suggest an association, although not significant, between... | 4 | 0biomedical | 0Study | [
"Neurology"
] |
314,586 | The most hotly debated is the male androgen hypothesis suggesting that male growth is masculinized by gonadal androgens. Sex-specific levels of gonadal steroids are generally important for the control of sexually dimorphic traits in vertebrates8 and the expression of many male-typical morphological, physiological and b... | 5 | 0biomedical | 0Study | [
"Endocrinology",
"Herpetology"
] |
38,841 | For the best fit, we explored the GFs of ITFs with 1st–5th order polynomial denominators to find a simple model. An ITF was derived for each subject and for each BDA, DAA, and BAA; the GF for each ITF was then determined. After collecting every GF of ITFs for each period pair, the order of the numerator and the order o... | 4 | 0biomedical | 0Study | [
"Biomedical Signal Processing"
] |
61,027 | First, we used population-immunostaining of filaments, where we determined the length of filaments at the end of the experiment. Here, the bacteria grew normally in batch culture without any manipulations prior to fixation (Figure 1C and E, Figure 2—figure supplement 1B). | 4 | 0biomedical | 0Study | [
"Microbiology",
"Molecular Biology"
] |
392,923 | To gain more insight into the interaction of ECMO and RBCs, we focused on the components that form the syllectogram, more than the composed AI. The AI did not significantly alter over time, but all components that make up the AI did. The basic laser scatter intensity, the upstroke, and the amplitude all significantly d... | 4 | 0biomedical | 0Study | [
"Hematology"
] |
397,015 | Illustration of a Mesostoma primary spermatocyte. There are two univalent pairs, acrocentrics in blue and metacentrics in yellow. There are three metacentric bivalents, in gray scale. Each bivalent has a tether extending between the telomeres of their free arms. The microtubule spindle is in green, with thick kinetocho... | 4 | 0biomedical | 1Other | [
"Cell Biology",
"Genetics"
] |
90,704 | This manuscript describes an elegant combination of molecular genetic experiments in vivo and biochemical assays in vitro leading the authors to suggest a much more detailed "prefabrication" mechanism used by yeast to overcome these challenges, to deliver r proteins S11 and S26 into adjacent positions in small ribosoma... | 4 | 0biomedical | 0Study | [
"Molecular Biology"
] |
8,000 | Participants were asked how often they smoked at present (0 = not at all; 1 = less than once a week; 2 = at least once a week, 3 = but not daily; 4 = every day). As previous studies reported whether or not youngsters smoke daily and due to violation of the linearity assumption, tobacco consumption was dichotomised into... | 3 | 0biomedical | 0Study | [
"Epidemiology"
] |
346,120 | We know that ucMDA (not just the total cost of MDA) depends on N.35 The elasticity of ucMDA with respect to population size is about −0.5, meaning that for a 10% increase in N, ucMDA decreases by a mean of 5%. We therefore used a published web-based application (https://healthy.shinyapps.io/benchmark/35) to generate es... | 4 | 0biomedical | 0Study | [
"Epidemiology",
"Global Health"
] |
214,909 | The overall prevalence of MDR among both of the isolates was 58.0% (199/343). Individually, 59.2% (179/302) of the total E. coli isolates and 48.7% (20/41) of the K. pneumoniae isolates were reported as MDR (Table 4).Table 4Distribution of MDR, ESBL and Carbapenem resistant in E. coli and K. pneumoniae in relation to g... | 4 | 0biomedical | 0Study | [
"Microbiology"
] |
254,212 | The Myeloid panel was used to confirm mutations in some BM or PB samples. A spreadsheet, included in Supplementary file 2, summarizes the variants, VAFs and coverages detected by T cell and Myeloid targeted panels. Overall, the results were concordant in the overlapped genes between two assays. | 3 | 0biomedical | 0Study | [
"Genetics",
"Molecular Biology"
] |
152,472 | The clinicians said that they regularly offered self-care advice when not prescribing immediate antibiotics and sometimes delayed antibiotic prescriptions. Those that had offered delayed prescriptions indicated that they thought that parents were generally accepting of these. Clinicians emphasised the importance of pro... | 2 | 1clinical | 1Other | [
"Pediatrics",
"General Practice"
] |
137,230 | SARS-CoV-2 infection can induce systematic and respiratory disorders (34). The most common symptoms of COVID-19 are high fever, consistent dry cough, and loss of smell and taste sense (10). Several COVID-19 patients showed symptoms of viral pneumonia, such as sore throat, fatigue, and myalgia (11). The most serious cas... | 3 | 0biomedical | 0Study | [
"Virology"
] |
388,479 | WHO defines severe respiratory distress in children presenting with tachypnea and any of the following: central cyanosis or hypoxemia (oxygen saturation [SpO2] < 90%), grunting, inability to breastfeed or drink, lethargy, unconsciousness, or convulsions.21 Age-specific tachypnea definitions are respiratory rate ≥ 60/mi... | 4 | 0biomedical | 1Other | [
"Pediatrics"
] |
113,991 | Four groups of mice (n = 15 per group) were used for survival study. After the treatments, the mice recovered soon, and mortality was observed and recorded to 48 h. hUC-MSCs, FTY720, and combinatorial treatment groups had higher survival rate compared with PBS group at 48 h. The survival rate of combination therapy gro... | 4 | 0biomedical | 0Study | [
"Stem Cell Biology",
"Immunology"
] |
372,519 | a In each class, DIR genes involved in segmental duplication (SD) and tandem duplication (TD) were counted. b In each class, the properties of DIR proteins including molecular weight (MW), isoelectric point (pI), and the number of putative N-glycosylation sites (N-gly) were investigated, and the median values were disp... | 4 | 0biomedical | 0Study | [
"Genetics",
"Bioinformatics"
] |
26,985 | Immunocytofluorescence analysis of astrocytic Cx43 expression in the normal group showed that Cx43 was mainly expressed discontinuously in plasma membrane and some in the cytoplasm (Fig. 2, a1). At high magnification, Cx43 was mainly expressed in gap junctions; also, there was some punctate distribution elsewhere (Fig.... | 4 | 0biomedical | 0Study | [
"Neuroscience"
] |
179,497 | The total (cumulative) impact factor for a total of 4699 publications was 14,130. The generated IF per department ranged from 1906 to 35. The mean cumulative IF per department was 372 (median 285; IQR 290). The IF per member ranged from 73.3 to 4.9; the mean was 32.0 (median 29.3) per member. As apparent for the sum of... | 3 | 0biomedical | 0Study | [
"Other"
] |
121,370 | Complex IP‐IMRT plans using multiple beam angles and complex intensity modulation not only result in a prolonged treatment time, they also reduce “radiation efficiency” because of the use of many small segments (in static IMRT delivery) and numerous narrow openings (in dynamic IMRT delivery). Inefficient radiation subj... | 4 | 0biomedical | 0Study | [
"Radiation Oncology"
] |
344,009 | Systemic steroid therapy is the standard first-line treatment for aGVHD [6–8]. However, in ~35–50% of patients, aGVHD becomes refractory to systemic steroid therapy [9, 10]. Mortality is high and quality of life is poor in these patients, and only one treatment is currently approved for steroid-refractory aGVHD (SR-aGV... | 4 | 0biomedical | 2Review | [
"Immunology",
"Hematology"
] |
230,881 | Of the 635 articles analyzed in the screening process, 554 (87.2%) were published in the last 5 years, since 2014. This reflects the increasing relevance of digitalized postoperative pain management in recent years. Correspondingly, this is apparent in the final pool of 11 articles, with 45% (n=5) published in 2018 and... | 2 | 0biomedical | 0Study | [
"Pain management",
"Anesthesiology"
] |
255,861 | Recipe of CNTs@TiN@TiO2 (2/5/10 nm)InstructionNumberValue1Heater141502Heater151503Stabilize15/4Stabilize14/5Wait/72006Pulse40.157Wait/208Pulse30.0159Wait/2010Goto6125/250/50011Flow/512Heater1415013Heater1515014Stabilize15/15Stabilize14/16Wait/60017Pulse40.518Wait/1019Pulse00.0320Wait/1021Goto1740/100/20022Flow/10 | 1 | 2other | 1Other | [
"Materials Science",
"Nanotechnology"
] |
254,220 | 5. The data on different SNV patterns in "CH" and "late" mutations are intriguing, although need validation, and leave some aspects open. The tobacco-related "Signature 4" is characterized by C>A mutations with strand bias – was strand bias observed in these data? | 2 | 0biomedical | 1Other | [
"Genetics"
] |
181,872 | The other positive indicator with appropriate complementary feeding practice was advice on breast feeding from health workers. Children whose mothers received breast feeding information from health workers were 3.5 times more likely to practice ACFP than children whose mothers received information from other sources (A... | 2 | 0biomedical | 0Study | [
"Nutrition",
"Pediatrics"
] |
202,222 | According to the logistic regression model, young adults with a higher level of education and young adults who are still in education are less likely to smoke on a daily basis. In contrast, sex and place of residence do not predict whether young adults smoke cigarettes on a daily basis or not (Table 5). | 4 | 0biomedical | 0Study | [
"Epidemiology"
] |
194,774 | The protective allele T of rs492554 enhances the potential binding affinity of transcription factor POU2F1. (A) Genome browser tracks for functional annotation of the upstream and downstream flanking sequences of SESN2 in heart or fetal heart tissues. (B) EMSAs were performed using biotin-labeled double-stranded oligon... | 4 | 0biomedical | 0Study | [
"Molecular Biology",
"Genetics"
] |
379,168 | By far, enormous efforts have been done to develop an antiviral agent against CoVs’ entry proteins, polymerases, proteases, and methyl transferases, but none has demonstrated successful clinical trials. Only limited therapeutic results have been obtained using recombinant interferon therapy supported with ribavirin. Ho... | 4 | 0biomedical | 2Review | [
"Virology"
] |
112,390 | Adult patients with stage 3 AKI , were included, with or without mechanical ventilation need, on exclusive artificial nutrition (enteral and/or parenteral) at the time of the first IC, and expected to have an ICU stay of at least 3 days. Exclusion criteria were based both on specific comorbidities and on the presence o... | 3 | 0biomedical | 0Study | [
"Nephrology"
] |
348,361 | Tubal (or ciliated cell) metaplasia of the endometrium is characterized by ciliated columnar cells with bland round nuclei and eosinophilic cytoplasm, similar to the cells normally seen lining the fallopian tube . It is generally thought that endometrial tubal metaplasia (ETM) is a benign disease. However, some studies... | 4 | 0biomedical | 0Study | [
"Pathology"
] |
252,976 | Flowers from Coreopsis have been used for ethnopharmacological purposes due to its known biological activities including anticancer, antioxidant, anti-inflammatory, and anti-diabetic effects. Kim et al. performed metabolic profiling and their inhibitory effect on dipeptidyl peptidase from five original cultivars and mu... | 2 | 0biomedical | 0Study | [
"Pharmacology"
] |
279,643 | Total eight detection points were deployed on the radial and ulnar side of the simulated arm (Sawbones, Vashon Island, WA, USA). Six of them were the pressure sensors, as listed at Table 1. Two of them were the temperature and humidity sensors, respectively, as shown in Figure 3. The points of pressure sensors were ind... | 3 | 0biomedical | 0Study | [
"Biomechanics",
"Prosthetics"
] |
17,712 | A. NPC-039 cells were injected into the right flank of 6-week-old male nude mice. After injection of NPC-039 cells, nude mice were treated with either vehicle or Polyphyllin G (2 or 4 mg/kg) for 24 days. The growth of the xenograft tumors was referred to the measurement of the long and short dimensions of the tumors, a... | 4 | 0biomedical | 0Study | [
"Oncology"
] |
235,991 | The results of RRMSE(σpx) indicate an error decrease in the patterns, as follows: adjacent 6.16%, due to a more accurate position of the inhomogeneity; and opposite 11.58%, with the deformation-induced rotation of the inverse image suppressed. In adjacent driving, the inhomogeneity area ratio for the desired model was ... | 4 | 0biomedical | 0Study | [
"Biomedical Imaging"
] |
91,697 | Of the 195 countries studied, the five highest age‐standardized incidence rates were in New Zealand [54 (95% CI 39–73)], Australia [54 (95% CI 41–78)], Norway [26 (95% CI 18–32)], Sweden [26 (95% CI 20–35)] and the Netherlands [25 (95% CI 17–30)]. The top‐five highest age‐standardized DALY rates were in New Zealand [16... | 4 | 0biomedical | 0Study | [
"Epidemiology"
] |
254,807 | Sensitivity analyses may explore the use of alternative decision rules, such as varying the minimum report or FDR thresholds, and alternative methodologies, such as replacing BCPNN with the Gamma-Poisson Shrinker (15, 20) or Information Component Temporal Pattern Discovery (21). | 3 | 0biomedical | 0Study | [
"Bioinformatics"
] |
57,478 | Early hepatic response to obesity reversal. Representative images (A) and weights (B) of livers 14 days after dietary switch (n = 11–12/group). (C) Representative liver hematoxylin and eosin (H&E)-stained histological sections of the three groups. I, II and III are sections from 3 individual mice from the HFF→NC group,... | 4 | 0biomedical | 0Study | [
"Hepatology"
] |
4,235 | Although exact figures for rates of hysterectomy are difficult to obtain for developing countries it can be assumed to be very high due to the non-availability of levonorgestrel intrauterine system and other medical alternatives due to financial constraints, and as such TAH is often offered by default. This study will ... | 4 | 0biomedical | 0Study | [
"Gynecology"
] |
141,490 | The Ethics Commission of the University of Heidelberg Medical School approved the study in August 2017. The study was deemed to be without risk, including only anonymized analysis of routinely collected data. Consequently, the Ethics Committee of the University of Heidelberg did not request consent for this analysis. | 1 | 0biomedical | 1Other | [
"Research Ethics"
] |
1,402 | The optoelectronic properties of (CH3NH3)3Sb2I9 have been investigated by Hebig et al. recently . The compound has a zero-dimensional dimer structure comprising discrete bi-octahedral metal halide units Sb2I9 3− of face-sharing BI6 octahedra surrounded by CH3NH3 + cations to balance the charge neutrality. The complex a... | 4 | 0biomedical | 0Study | [
"Materials Science",
"Chemistry"
] |
160,043 | However, for school-aged population, a total of 375,374 were infected, requiring 2,685,618 drugs for preventive chemotherapy. Ten LGAs in the central and western part of the state had over 10,000 infected school-aged children, and requires over 100,000 albendazole or mebendazole tablets each, for mass administration ca... | 4 | 0biomedical | 0Study | [
"Epidemiology",
"Parasitology"
] |
111,438 | Infection occurs in all age groups but rarely affects children or the elderly (older than 60 years of age). The male to female ratio is 3 to 1. The cervicofacial region is involved in 60% of cases, as compared to 15% and 20% for thoracic and abdominal regions, respectively . The patient in our case had cervicofacial ac... | 3 | 0biomedical | 1Other | [
"Infectious diseases"
] |
337,957 | Differences in experimental designs can only partially account for such conflicting results. First, response modulations elicited by stimuli with negative valence such as fearful faces are different from those elicited by other negative valence stimuli such as angry or sad faces because they communicate diverse message... | 4 | 0biomedical | 0Study | [
"Neuroscience"
] |
78,257 | To characterize the cell death induced by PARP-1 and APR-246, we first determined whether the cell death is prompted by necrosis. Treatment with PHEN and/or APR-246 could not influence the expression of receptor interacting protein (RIP) kinases RIP1, RIP3, and phosphoglycerate mutase family member 5 (PGAM5), critical ... | 5 | 0biomedical | 0Study | [
"Cell biology"
] |
303,537 | For DNA extraction, DNA Mini Kit (Qiagen, Netherlands) was used. DNA recovered from the aforementioned process was chemically converted using EpiTectPlus DNA Bisulfite Kit (Qiagen, Netherlands), in order to turn unmethylated cytosines to uracil for detection by methylation-specific PCR. Next, the bisulfite-treated DNA ... | 4 | 0biomedical | 0Study | [
"Molecular Biology",
"Epigenetics"
] |
164,619 | Lines 604-635: Authors discuss differential recruitment of spinal neurons as a function of 'speed'. However, the studies cited looked at the recruitment of neurons as a function of frequency. It has recently become clear that speed can be changed even without changing swim frequency and that MNs are recruited as a func... | 4 | 0biomedical | 0Study | [
"Neuroscience"
] |
39,370 | The transcript profiles of B-PpRR genes were also investigated in the dormant floral buds of Japanese pear ‘Kosui’ (P. pyrifolia) . Four B-PpRR genes, B-PpRR9/6/7/8, showed significant differences in transcript levels among different stages. Among these genes, B-PpRR9/6/7 showed increased transcript levels during endod... | 5 | 0biomedical | 0Study | [
"Plant Genetics"
] |
277,228 | The histopathological structure of CA3 regions of the hippocampus and dentate gyrus (DG) and was assessed in this study as they are involved in controlling the mood. The CA3 region consists of three cell layers: the molecular, polymorphic, and pyramidal layers. The latter is formed of several layers of pyramidal nerve ... | 4 | 0biomedical | 0Study | [
"Neuroanatomy",
"Neuroscience"
] |
380,073 | The excessive accumulation of ROS may promote plant cell death. Hydrogen peroxide (H2O2) is a major type of ROS. Here, we assayed if His-TF-RcMEP2 protein triggers H2O2 excessive accumulation when infiltrated in the N. benthamiana leaves. The diaminobenzidine (DAB) staining for H2O2 detection was observed and photograp... | 4 | 0biomedical | 0Study | [
"Plant molecular biology"
] |
36,005 | From imprecision data it was demonstrated that the ETP, Peak thrombin generation and TTP parameters were significantly different between deficient plasma and 0.1% (v/v) normal in deficient plasmas (p<0.01). Limit of detection of the assay is therefore set to ≤0.1% (v/v) normal in HA or HB plasma. | 4 | 0biomedical | 0Study | [
"Hematology",
"Coagulation"
] |
125,529 | Impacts of organic and conventional tea farming methods on residual levels of NEOs in Japanese tea leaves were evaluated by comparing the detection frequencies and distribution frequencies of NEOs among the two farming methods (Table 2 and Fig. 1). Interestingly, all the target NEOs were detected with appreciable frequ... | 4 | 0biomedical | 0Study | [
"Environmental Toxicology"
] |
131,304 | Total RNA was isolated with Trizol reagent (Thermo Fisher Scientific) and reverse‐transcribed with EASTWIN system according to the manufacturer's instructions. The expression levels of GLUT1 and HK2 were detected by real‐time quantitative PCR (RT‐qPCR) using StepOne real‐time PCR system (Applied Biosystems) and β‐actin... | 4 | 0biomedical | 0Study | [
"Molecular Biology"
] |
356,121 | In your Competing Interests statement, please confirm that your commercial funding does not alter your adherence to PLOS ONE Editorial policies and criteria by including the following statement: "This does not alter our adherence to PLOS ONE policies on sharing data and materials.” as detailed online in our guide for a... | 1 | 2other | 1Other | [
"Publishing and Research Ethics"
] |
379,091 | The findings of this study suggest that concurrent therapy with icotinib and RT was well tolerated and tended to improve survival in older patients with ESCC. Patients with EGFR overexpression seemed to benefit more from icotinib with RT. A phase III trial to further identify the efficacy of icotinib with RT is forthco... | 4 | 0biomedical | 0Study | [
"Oncology"
] |
283,647 | Telomeres are repeated DNA-sequences (TTAGGG)n associated with a protein complex known as shelterin at the ends of chromosomes. The fundamental role of telomeres is to preserve genome stability . Loss of telomere functionality is associated with activation of DNA damage response machinery that can result in chromosome ... | 4 | 0biomedical | 0Study | [
"Molecular Biology",
"Genetics"
] |
108,471 | In both human and yeast, RAS is activated in response of the presence of growth and pro-survival signals, specifically growth factors in the case of human RAS and glucose in the case of yeast RAS . Though RAS stimulates growth, meant as an increase in cell number, these effects are not always achieved in the same way ... | 4 | 0biomedical | 0Study | [
"Molecular Biology",
"Cell Signaling"
] |
256,340 | A recent study by Chin et al. (18) reported that SARS-CoV-2 survived at room temperature with 65% relative humidity for 7 days on plastic surfaces and 7 days on stainless steel surfaces before complete inactivation, was infectious on glass for 2 days, and was completely undetectable after 4 days. During the outbreak, S... | 4 | 0biomedical | 0Study | [
"Virology"
] |
267,242 | I feel like it’s just been a leaflet and that’s kind of it. I don’t think I’ve ever asked, you know, what is it that goes into this, tell me the actual ingredients in a layman’s way that I’m going to understand. I feel like if I did ask, I’m not sure how well they’d actually be able to tell me as well (Stacey, Non‐Vacc... | 1 | 2other | 1Other | [
"Vaccinology"
] |
127,816 | Finally, we analyzed whether R848 + poly(I:C) increased the specific migration of DCs toward the chemokines CCL-19 and CCL-21. pDCs migrated toward CCL-19 only upon activation with R848 + poly(I:C) (52.3 ± 5.4%). For cDCs, TLR-activation increased migration from 44.9 ± 4.8% to 83.5 ± 3.6% (p = 0.031) upon TLR activatio... | 4 | 0biomedical | 0Study | [
"Immunology"
] |
345,449 | As a result, branch order analysis or Sholl analysis can then be extracted. The detailed segmental and topological analysis of different compartments within the dendritic tree is crucial to find subtle morphological differences, which cannot be obtained by analyzing general data about neuron morphology (e.g., Groc et a... | 3 | 0biomedical | 0Study | [
"Neuroscience"
] |
15,814 | Specifications tableTableSubject areaEngineering, Materials ScienceMore specific subject areaAdditive ManufacturingType of dataTable, figureHow data was acquiredDesign of Experiments, ThermocoupleData formatRaw, AnalyzedExperimental factorsThe samples were 3D printed based on the experimental design factor treatments i... | 2 | 2other | 0Study | [
"Other"
] |
268,443 | One patient from each group required intubation within the first hour from surfactant administration due to clinical features of respiratory distress. All the patients experienced fast clinical improvement independent of the surfactant administration method, and the reduction of FiO2 concentration was most dynamic with... | 4 | 0biomedical | 0Study | [
"Neonatology",
"Respiratory Medicine"
] |
252,214 | The transport behavior of water molecules in the simulation models was observed via MD simulation. In the calculation period, the number of water molecules was tracked and recorded in each of the parts. In other words, the time-course curves for the number of water molecules as a function of time within the channel sim... | 4 | 0biomedical | 0Study | [
"Biophysics"
] |
385,305 | (*) Means (n = 8) in the same column followed by different uppercase letters are significantly different between treatment groups within the same evaluation period. Means (n = 8) in the same column followed by different lowercase letters are significantly different comparing the same treatment group among evaluations p... | 3 | 0biomedical | 0Study | [
"Biostatistics"
] |
358,673 | ‘[I]t boils down to being disciplined uh, you act professionally even though you maybe you may differ in which other way, some of the other things that people do but you try and like supress your emotions, you compromise, something’s are hard to solve, you have to compromise | 1 | 2other | 1Other | [
"Other"
] |
188,402 | In order to further explore the loss mechanism of the three-layer structure foam material, we can observe the change trend of the tg δε and tg δμ values of the six samples through Figure 7e,f. The value of tg δε shows an upward trend with the change of frequency. The value of tg δμ has an obvious upward trend at the be... | 4 | 0biomedical | 0Study | [
"Materials Science",
"Electromagnetism"
] |
348,364 | Scattered patterns or focal expression of p16 positive cells in serous EC and tubal tissue was described by several authors. They describe a pattern which is not seen in normal tissue and is different from diffuse p16 positivity as seen in high-risk HPV positive cervical intraepithelial lesions . Inoue reported that e... | 4 | 0biomedical | 0Study | [
"Oncology",
"Gynecology"
] |
383,679 | We analyzed data from 40,288 deceased donor primary liver transplantations reported to CTS and performed from January 1st, 1998 to December 31st, 2017 in adult patients with alcoholic liver cirrhosis or cirrhosis due to HCV and HCC. Less frequent original diseases such as autoimmune disorders, cryptogenic cirrhosis, co... | 4 | 0biomedical | 0Study | [
"Hepatology",
"Transplantation"
] |
193,875 | An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any bi... | 1 | 2other | 1Other | [
"Publishing administration"
] |
315,253 | All studies are done by uniformly releasing several microparticles from the inlet of the microchannel and subsequently tracking their trajectories to determine SE and SP; this approach has been previously adopted by researchers . One of the assumptions of this model is that the microparticles do not experience Brownian... | 4 | 0biomedical | 0Study | [
"Microfluidics"
] |
264,335 | TRIzol reagent (Invitrogen, CA, USA) was used to isolate total RNA from cells and tissues according to the manufacturer’s instructions. The cDNA was generated with random primers and amplified with a One Step PrimeScript RT-PCR Kit (Takara, Dalian, China). qPCR was performed using SYBR® Premix Ex Taq Kit (Takara, Dalia... | 4 | 0biomedical | 0Study | [
"Molecular Biology"
] |
350,668 | Generalized GA has been shown to occur in the setting of lymphomas, leukemias, myelodysplasias, and visceral malignancies, though the temporal relationship between presentation of GA and of the malignancy has not always been constant. 2 , 3 , 4 , 5 It has also been associated with diabetes, thyroid disease, systemic lu... | 5 | 0biomedical | 0Study | [
"Dermatology",
"Immunology"
] |
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