Split (2)

train · 358k rows

id int32 0 398k	text stringlengths 227 42k	educational_score float32 1 5	domain class label 3 classes	document_type class label 4 classes	subfield listlengths 1 4
25,688	A sub-national representative cross-sectional malaria medicine outlet survey was conducted in Kinshasa (11th September—11th October 2013). Methods for the surveys have been described in detail previously [6, 9]. Briefly, clusters with a population size of approximately 10,000 to 15,000 inhabitants, (“aires de santé”) w...	4	0biomedical	0Study	[ "Epidemiology" ]
157,358	S. maltophilia also influences biofilm formation by some P. aeruginosa strains by reducing EPS production and thus compromising biofilm attachment to the epithelial cell surface . These findings suggest that S. maltophilia in a mixed co-infection may benefit from increased abundance and growth while disrupting the biof...	4	0biomedical	0Study	[ "Microbiology" ]
238,633	Table 1 shows correlations among clay content, sand content, ECa, elevation, and slope. ECa was positively correlated with clay content and negatively related to sand content. ECa was reported to be strongly related to topsoil clay and sand content and also affected by water content . The bulk density of soil and the ...	4	2other	0Study	[ "Environmental science", "Soil science" ]
129,247	Then, the average marginal effect of variable xk on transition j is 1N∑n=1N[∂pj∂xk]X=Xn, where Xn = (xn1,…,xnK) denotes the nth individual in the data. We used the R package margins (https://cran.r-project.org/web/packages/margins/) to compute the average marginal effects of the multinomial transition models. The avera...	4	0biomedical	0Study	[ "Epidemiology" ]
153,806	The caveat to the capacitated STRING network is that the TUBB2B, a protein not identified in our mass spectrometry results but previously reported in sperm and implied to be a constituent of the beta-tubulin cytoskeletal complex , was included in our analysis to generate continuity within the protein–protein interactio...	5	0biomedical	0Study	[ "Cell Biology", "Reproductive Biology" ]
242,001	Science continues to improve the design and function of nonpharmaceutical technologies such as face masks, air filtration, and germicidal UV for cleaning of air in commercial markets, sparked by the COVID-19 pandemic4,5. Adoption and integration, of these and other simple technologies, each a beneficial response to the...	2	0biomedical	1Other	[ "Environmental Health" ]
352,304	One of the fundamental ideas of molecular biology is the central dogma [14, 15], which describes the process of information flow via a two-step process of transcription and translation, where the information in genes flow to proteins: DNA to mRNA, and mRNA to protein. Further, the central dogma explains that this trans...	4	0biomedical	1Other	[ "Molecular Biology" ]
213,693	BLOSUM62 cluster map showing sequence similarity of echinoderm SS1-type and SS2-type peptide precursors with SS/ASTC-type peptide precursors in other taxa. Nodes are labeled with phylum-specific colors, as shown in the key, and connections represent BLAST relationships with a P value >1e-2. Vertebrate precursors of UII...	4	0biomedical	0Study	[ "Bioinformatics", "Neuroendocrinology" ]
32,180	Recently, MSCs injection resulted in lower pro-inflammatory and apoptotic scores, and higher anti-inflammatory and mitogenic indices, thus effectively ameliorating experimental AKI43–50. Because this positive functional effect was accompanied by rapid disappearance of administered MSCs from the kidney, it is supposed t...	4	0biomedical	0Study	[ "Stem Cell Biology" ]
94,143	Haffer (1974), who measured 66 A. prasinus (sensu lato), treated all forms as subspecies. Given evidence of hybridization in two cases in the A. “prasinus” complex, he concluded that differences would probably not prevent interbreeding; he thus retained the post-Peters (1948) taxonomy for this group. The evidence of in...	4	0biomedical	0Study	[ "Evolutionary biology", "Ornithology" ]
251,116	We then looked at the total overlap of genus or species to determine if there are similarities in recovered microbial or viral sequences between datasets. For genus in the regular bacteriome, our dataset had the highest number of unique genus (185), followed by Ladd et al. (2017; 117), and Gagliardi et al. (2018; 38). ...	4	0biomedical	0Study	[ "Microbiology", "Virology" ]
364,008	Macrophages were fixed with 4% paraformaldehyde for 15 min, followed by incubation of the cells in blocking buffer (Thermo Fisher Scientific, Waltham, MA, USA) for 30 min. Thereafter, the samples were stained with mouse anti-MHC class II (HLA-DP β1) antibody (Abcam, Cambridge, UK) in blocking buffer. Following overnigh...	4	0biomedical	0Study	[ "Immunology" ]
289,216	The Child PTSD Symptom Scale—V (CPSS-V) [(34); Portuguese version: (removed for blind review)] is a self-report measure that aims to assess the severity of PTSD symptoms presented in the past month by children and adolescents after having being exposed to a traumatic event. The inventory comprises 20 items correspondin...	4	0biomedical	0Study	[ "Psychiatry", "Psychology" ]
107,714	This study aimed to evaluate the impact of an innovative web-based school nutrition intervention (i.e. Team Nutriathlon) on the consumption of V/F and M/A in high school students, a population where there is a need to improve eating habits and develop nutrition programs. The results of this study suggest that Team Nutr...	4	0biomedical	0Study	[ "Nutrition" ]
188,569	The focus of this study is to solve the task of cotton leaf spot classification in small samples. In this study, 10 or 15 categories are randomly selected for each spot in the dataset, and then a certain number of images are randomly selected from these categories to form the training dataset, and 5, 10, 15, and 20 ima...	2	2other	0Study	[ "Plant pathology" ]
108,330	In accordance with the present study, Feizi et al.'s study on 4583 people aged 19 and older, living in Isfahan, Iran, showed that family conflicts and social problems are significantly correlated with the levels of perceived stress, which may be related to different Iranian cultural aspects that people are more sensiti...	4	0biomedical	2Review	[ "Psychiatry", "Psychology" ]
78,957	Tables 1 and 2 show the general characteristics of eligible studies. The 19 eligible studies included a total of 2321 patients, with a median number of 92 patients per study (range: 12–487). None of the selected studies was a randomized prospective study. Seven of the 19 included studies were non-randomized prospective...	4	0biomedical	0Study	[ "Urology" ]
212,693	A vaccine adjuvant, which is an immunostimulatory component of a vaccine formulation, is often very important for the successful vaccination of an antigen . Most recently developed vaccines do not apply the entire pathogen but rather use certain components (e.g., major proteins) as antigens . However, a subunit vaccine...	4	0biomedical	1Other	[ "Immunology" ]
354,651	To measure the water contact angles (CAs) of the three materials, disc-shaped (8 mm in diameter, 1 mm in thickness) specimens were fabricated with a Teflon mold (n = 6/group). The pastes were filled into the molds and light-cured on both flat surfaces. The CAs of water (3 μL) on the cured material surfaces were recorde...	4	0biomedical	0Study	[ "Biomaterials" ]
34,488	In the Andean sierra alta, the deep valleys and abrupt terrains that stretch out from 2,500 to 3,800 masl support Aymara agro-pastoralists who cultivate potato and other tubers (oca, ulluco), quinoa, barley, as well as other vegetables. Above 3,800 masl, the puna sustain a more exclusively pastoralist agriculture of mi...	1	2other	1Other	[ "Geography", "Agriculture" ]
205,528	The Ovid MEDLINE search strategy was presented in the published protocol (Teixeira et al., 2019). We adapted the search syntax to suit grey literature resources. The full search strategies for all databases were revised by an information scientist and are presented in Appendix 1 in the Supplementary data. Searches were...	2	0biomedical	2Review	[ "Epidemiology", "Research Methodology" ]
289,954	Subgingival bacterial samples were obtained from the 36 animals by a curette and analyzed using a MiSeq instrument [29, 30] for the total composition of the microbiome from each sample [31, 32]. Sequences were clustered into phylotypes based on their sequence similarity, and these binned phylotypes were assigned to the...	4	0biomedical	0Study	[ "Microbiology" ]
69,160	An initial calibration (both SDK-based and our designed one) is performed once for a single (first) participant and the calibration results are applied on the remaining participants. The position of the chin rest and the eye tracker are not altered for the remaining participants. Next participant onwards, 2 tests (NG a...	2	0biomedical	0Study	[ "Ophthalmology", "Neuroscience" ]
146,812	The proposed pathway shows comparable results with other DTAP for managing patients undergoing femur fracture surgery. In particular, the obtained reduction of 39% in the preoperative LOS is slightly higher than the one obtained Kosy et al. in a district general hospital in South West England but it is lower when comp...	4	0biomedical	0Study	[ "Healthcare Management" ]
352,359	At Week 4 of any treatment cycle, the estimated maximal change from baseline MAS score in the PTMG was −1.8 (95% CI, –2.0; –1.6) (Fig. 1A), with 90% of the asymptote reached after an estimated 2.3 (95% CI, 1.7; 3.3) cycles; at Week 12 the estimated maximal change from baseline was −1.6 (95% CI, –2.0; –1.2) (Fig. 1B), w...	4	0biomedical	0Study	[ "Pharmacology", "Toxicology" ]
271,352	Tamoxifen is an estrogen receptor antagonist commonly used to treat patients whose breast cancer are estrogen receptor-positive , and has been shown to experimentally prolong QT interval duration by direct inhibition of rapidly activating delayed rectifier potassium (IKr) channels and clinically by affecting cytochrome...	4	0biomedical	0Study	[ "Pharmacology", "Cardiology" ]
119,146	Data were analyzed using Stata (version 14; StataCorp., College Station, TX, USA) using survey weightings for analyzing complex survey data to account for the survey design. These weightings were specifically designed to account for bias associated with those who volunteered to complete the second day of dietary recall...	3	0biomedical	0Study	[ "Epidemiology" ]
393,690	All subjects will undergo a general medical, psychiatric and neurological assessment. Presence of psychiatric disease and symptoms will be determined according to DSM 5 criteria and Neuropsychiatric Inventory (NPI) respectively. Depression severity will be assessed using the Montgomery-Åsberg Depression Rating Scale (M...	4	0biomedical	0Study	[ "Psychiatry", "Neurology" ]
164,407	Analysis of data from the fits in Figure 2A. (A) A plot of koff obtained for each injection versus [RBD]. (B) A plot of kobs for each injection versus [RBD]. The line shows a constrained fit of the equation kobs = kon*[RBD]+ koff, using the koff obtained in (A). The kon was obtained from the slope.	4	0biomedical	0Study	[ "Biochemistry", "Molecular Biology" ]
84,542	Balance was measured with the Berg Balance Scale (BBS). The BBS measures a person's ability to balance during 14 different tasks of varied difficulty. Items are rated by a scale from 0 to 4 and are summed to the total score which has a maximum (best) value of 56. The BBS is a valid and reliable test of balance in pwMS ...	4	0biomedical	0Study	[ "Neurology", "Physical Therapy" ]
232,539	For application of the ACS in real-world clinical practice, its validation with experts from diverse clinical backgrounds, in terms of accuracy, time saving, and user satisfaction, would be necessary. However, our previous studies did not focus on the generalizability or real-world use [7, 8]. In this study, we evaluat...	2	0biomedical	0Study	[ "Radiation Oncology" ]
207,433	Despite evidence-based diverse medical and socioeconomic benefits of contemporary vaccination schemes (for both particular persons and the whole populations) , there are substantially growing public concerns worldwide regarding the efficacy and safety of active immunization procedures, in particular due to disinformati...	4	0biomedical	2Review	[ "Immunology" ]
94,077	Recruitment to the panel was via an expression of interest circulated to the IACS membership, as well as targeted invitations to experts in scabies and tropical dermatology known to the working group or panel members. Moderators did not participate in the survey rounds. A panel of 10–15 members is usually recommended ....	2	0biomedical	1Other	[ "Dermatology" ]
101,936	The selected TG1 clones were replicated into a 2 mL plate with 96 wells, which contained 500 μL of 2× YTAG medium (1% yeast extract, 1.6% tryptone, 0.5% NaCl, 100 μg/mL ampicillin, 0.1% glucose). After incubation at 37 °C for approximately 5 h at 200 rpm, the scFv protein expression was induced by 0.5 mM IPTG for 20 h ...	4	0biomedical	0Study	[ "Molecular Biology", "Immunology" ]
337,296	(A) Regression analysis. The individual delay in phonological response speed after effective continuous theta burst stimulation (cTBS) over pIFG vs. sham cTBS (pIFG – sham cTBS) was correlated with the upregulation of the contralesional right supramarginal gyrus (SMG; shown at p<0.001 uncorrected for display reasons). ...	4	0biomedical	0Study	[ "Neuroscience" ]
196,480	Once its activity over hyperglycemia was demonstrated, EESpS was subjected to partition, obtaining two fractions, AqRFr and EtOAcFr, which were also evaluated in diabetic mice (Table 2). Both fractions significantly reduced blood glucose from 30 to 120 min; this activity was similar to that of the control drug, acarbos...	4	0biomedical	0Study	[ "Pharmacology" ]
288,419	At x ~ 0, the abrupt increase in pressure from 0 to 10 GPa generates an inversion (⊠) of the Zn–Te doublet (Fig. 3c). Moreover at 10 GPa a massive transfer of oscillator strength is observed—to a point that the two Zn–Te sub-modes exhibit similar Raman intensities. This proves the «free» Zn–Te coupling. A similar inver...	4	0biomedical	0Study	[ "Materials Science", "Biophysics" ]
34,911	On admission to our hospital, the patient was dyspneic, with nasal alar flaring and retraction, cyanosis in the lips and nail beds. There were no rales or cardiac murmurs on auscultation of the chest. The laboratory investigations showed a white blood cell count of 14,090/mL with 66.6% neutrophils, hemoglobin (Hb) 9.8 ...	4	0biomedical	3Clinical case	[ "Pulmonology", "Genetics" ]
218,087	Please ensure that the paper adheres to the PLOS Data Availability Policy (see http://journals.plos.org/plosmedicine/s/data-availability), which requires that all data underlying the study's findings be provided in a repository or as Supporting Information. For data residing with a third party, authors are required to ...	1	2other	1Other	[ "Research publication guidelines" ]
294,146	For further analysis, a 2 × 12 (Drug × Neural Substrate) mixed two-way ANOVA indicated that, on conditioning, significant differences occurred in drug (F1, 10 = 47.78, p < 0.05), neural substrate (F11, 110 = 119.02, p < 0.05), and drug × neural substrate (F11, 110 = 15.20, p < 0.05). One-way ANOVA indicated that signif...	4	0biomedical	0Study	[ "Neuroscience" ]
236,562	The blood transcriptome of E. scophthalmi-challenged fish did not exhibit significant changes in the specimens classified as incipient and slightly infected. This observation can be related to the long pre-patent period of enteromixosis , and the fact that subtle changes occurring in the early phase of the infection ar...	4	0biomedical	0Study	[ "Parasitology" ]
244,136	The following inclusion criteria were adopted in the articles' selection phase: (1) Studies with an analytical study design as defined by Grimes and Schulz (2002), in particular prospective and retrospective, case-control, longitudinal, cohort studies, randomized and clinical trials; (2) studies concerning the incidenc...	4	0biomedical	0Study	[ "Oncology" ]
358,004	The mechanism underlying poor retention after punishment feedback may be indicative of the motor learning process employed by those in the Punishment group. It has been suggested that motor adaptation is comprised of “fast” and “slow” processes. “Fast” processes are characterized as being highly sensitive to error, rap...	4	0biomedical	0Study	[ "Neuroscience" ]
244,000	In memory of Dr. Darshan Singh Brar. From top left to bottom right: Dr. Brar (1) the cytologist, (2) the geneticist, (3) the wise, (4) the contemplator, (5) the mentor (with Dr. Kofi Bimpong and Ms. Joie M. Ramos), (6) the breeder, (7) the teacher (with Mr. Jiawu Zhou). Pictures 1–5 are from the IRRI archives (see http...	1	2other	1Other	[ "None" ]
288,373	Using the parameters that need to be learned in the network and linear transformation: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ {y...	3	0biomedical	1Other	[ "Bioinformatics" ]
38,838	The TF, G(z), is a function that can show a relation between the input signal, X(z), and the output signal, Y(z) when z means discrete-time signal in a complex frequency domain: G(z) = Y(z)/X(z). Generally, the TF of a discrete signal comprises a fraction including the n-th order polynomial numerator and m-th order pol...	3	0biomedical	0Study	[ "Biomedical Engineering" ]
127,666	At last, participants reported their financial risk propensity, in which the items were extracted from the Domain-Specific Risk-taking (adult) Scale (Blais and Weber, 2006). The scale is wildly used as a measurement of dependent variable in research on risk propensity (Ben-Zur and Zeidner, 2009; Devlin et al., 2015). I...	4	0biomedical	0Study	[ "Psychology", "Behavioral Economics" ]
69,167	The variable error also arises due to eye tracker hardware, exhaustion or fatigue of the user, etc. Thus a closeness measure (CL) is also required to know how the points deviate or spread across its cluster center. We have computed the CL of the data chunk with respect to its cluster center as given by Eq (18), CL=∑i=1...	3	2other	1Other	[ "Data analysis", "statistics" ]
143,791	Mectizan is the trademarked name for Ivermectin, and is the name known in the communities. The severity of onchocerciasis, particularly skin diseases (onchodermatiatis) was reported as common in the communities as evidenced through descriptions of ‘leopard skin’. Although some community members and CDDs noted that, pri...	2	0biomedical	0Study	[ "Parasitology" ]
42,238	Chicken and duck ND5 and cytb gene abundances were determined by qPCR using the LightCycler 480 real-time PCR detection system (Roche480, USA). A 20 μL aliquot of qPCR mixture contained 10 μL of 2× TaqMan® Gene Expression Master Mix (Applied Biosystems, Foster City, CA, USA), 0.9 μM each of forward and reverse primers,...	4	0biomedical	0Study	[ "Molecular Biology" ]
382,147	DSSs need large heterogeneous databases to create a prediction model with a good statistical power underlying the importance of homogeneity of collected data and of a shared language . The ontology-based methodology supports the creation of large databases . Ontology “is a (formal) specification of concepts, relations ...	2	0biomedical	1Other	[ "Bioinformatics" ]
13,322	The increase in glucose and NEFA after IMI observed in our and other studies can be associated with the inflammatory response. The proinflammatory cytokine TNFα is known to induce temporary insulin resistance in monogastrics . The work from Kushibiki and collaborators demonstrated that this effect is conserved in rumi...	4	0biomedical	0Study	[ "Immunology" ]
50,484	The assays used for eDNA-detection of Atlantic salmon and rainbow trout (Table 2) follow Matejusova et al. and Wilcox et al. , respectively. These were successfully tested on DNA extracts from tissue of Atlantic salmon and rainbow trout before use in the current study (data not shown). The ddPCR assay for G. salaris, ...	4	0biomedical	0Study	[ "Molecular Biology", "Genetics" ]
293,805	It has been demonstrated that in prostate cancer full‐length XAF1 might be downregulated while truncated isoforms are expressed. 54 However, such tendency was not observed in colorectal cancer where downregulation of full‐length XAF1 was accompanied with reduced expression of other variants as well. 16 Furthermore, the...	4	0biomedical	0Study	[ "Oncology" ]
234,727	The Rosa “Hurdal” (A) single-node leaf cutting, (B) phenological stages of shoots in terms and their treatment in experiment (C) phenological stages in BBCH scale (Meier et al., 2009): H1−54,504 (flower buds still closed); H2−69,605 (full flowering; at least 50% of flowers open); H3−69,629 (end of flowering of the seco...	4	0biomedical	0Study	[ "Botany", "Horticulture" ]
194,577	In this study, the saliency map method is simply modified for regression issues to determine the SSC. As for classification issues, the saliency map is calculated using the correctly classified samples. Similarly, for regression issues, we define the “correctly predicted sample” to calculate the saliency map. The predi...	4	0biomedical	0Study	[ "Spectroscopy" ]
343,810	Neutralizing Ab titers, Virus specific IgG and IgA antibody titers and frequency of IFNγ secreting cells were performed as previously described (25). The phenotype of NP217-225 SLA tetramer binding specific CD8 T cells was established by flow cytometry on cryopreserved lymphocytes as described before (31). Briefly, bio...	4	0biomedical	0Study	[ "Immunology" ]
352,175	The prevalence of EBF, defined as giving only breast milk and no extra fluids or solids since the previous study visit, was lowest in the first month of life 45% (9/20 mothers) and highest in the third month 70% (14/20) (Fig. 1). Only two (10.5%) mothers practiced this from birth to 6 months. There were no obvious feat...	4	0biomedical	0Study	[ "Pediatrics", "Neonatology" ]
353,519	To apply the QLI, WHOQOLBREF, and CQS in the measurement of QoL of polio survivors in northwest Nigeria, there is a need to cross-culturally adapt and validate the instruments in the northwestern Nigerian context . Generally, cross-cultural adaptation involves translation of an instrument from a source language to targ...	4	0biomedical	0Study	[ "Epidemiology", " Public Health" ]
33,646	The suspension of LiAlH4 (3.8 mg, 0.1 mmol) was added to a cold (−10°C) solution of 1 (21.8 mg, 0.1 mmol) in THF (15 ml) under argon and vigorous stirring. After 1 h (TLC control) the reaction was stopped by successive addition of water (2 drops), 6 N NaOH solution (2 drops) and water (4 drops). The mixture was extract...	3	0biomedical	0Study	[ "Organic Chemistry" ]
89,033	Nine caregivers (15%) reported high levels of distress (defined as a score of ⩾4 on GHQ-12). The median score of psychological distress was 1.00 (IQR 0.00–2.50): 1.00 (IQR 0.00–3.00) in caregivers of involuntarily admitted patients and 0.00 (IQR 0.00–1.00) in caregivers of voluntarily admitted patients. Caregivers of i...	3	0biomedical	0Study	[ "Psychiatry", "Psychology" ]
205,001	Dizziness, one of the neurosensory symptoms, was found in the elderly frequently and even more in elderly patients with dementia for prevalence varying from 14.2% to 77.5% [38–42]. The neurobehavior consequences, such as psychiatric and neurodegenerative disease of mTBI patients, may be persisted [43–46]. Therefore, th...	2	0biomedical	0Study	[ "Neurology" ]
396,366	The average tumor size was 12 mm (range 2–20) in the AI group, 23 mm (range 6–66) in the EI group, and 27 mm (range 5–65) in the BEI group (P < 0.001) (Table 2). Most lesions were smaller than 20 mm (73.7%, 370/502). The most common site of EGCC was posterior curvature (51.0%, 256/502), followed by lesser curvature (42...	5	0biomedical	0Study	[ "Oncology", "Gastroenterology" ]
365,000	While some health care leaders hold an MHA degree,23 distinct differences exist between the MHA and MPH curricula. The MHA curricula is more financial/business management focused and often lacks curricula attention to public organizations inherent in public health coursework and practice.24,25 The MPH in HPAL includes ...	3	0biomedical	1Other	[ "Public Health" ]
313,604	Some experimental models have investigated MEK inhibitors for MAP2K1 in-frame deletions [15, 16, 26, 27]. Gao et al. reported in vitro experiments where Classes 1 and 2 MAP2K1 mutants were effectively inhibited by allosteric MEK1 inhibitors, while Class 3 mutants, represented by in-frame deletions, were resistant . The...	4	0biomedical	0Study	[ "Oncology", "Molecular Biology" ]
16,525	All hospitals entered the trial in April 2016. The study is conducted in 40 out of 48 eligible public hospitals in the province of Québec. To be eligible, each center was required to offer TOL after cesarean in their population; to have a minimum of 300 deliveries in the previous year; to have functional operating room...	4	1clinical	1Other	[ "Obstetrics" ]
4,656	Considering that hypoxia can increase reactive oxygen species (ROS) generation in ASCs by a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent mechanism [23, 24] and that the disproportionate increase in ROS could affect the functions of ASCs , we evaluated the expression levels of several members of...	4	0biomedical	0Study	[ "Cell biology" ]
164,522	V2as were considered the primary source of rhythmogenesis in our models of beat-and-glide swimming based on previous studies showing the necessity and sufficiency of V2a neurons to swimming activity (Eklöf-Ljunggren et al., 2012; Ljunggren et al., 2014). In the swimming model, V2as projected segmental and descending pr...	4	0biomedical	0Study	[ "Neuroscience" ]
386,723	In this report, we presented a workflow for processing RNA-seq data that allows the rational diagnosis of top connected hubs among genes that are up-regulated in tumors according to the non-tumoral peripheral area (stroma). The use of the stroma as a control to measure the malignant differential expression via RNA-seq ...	4	0biomedical	0Study	[ "Bioinformatics", "Genomics" ]
343,111	The two-parameter logistic growth model is useful as a simple benchmark for comparing the performance of the more complex models. The well-known three-parameter Richards model extends the logistic growth model to include an additional parameter to allow for asymmetry in the decline of the epidemic curve . If the data f...	3	0biomedical	0Study	[ "Epidemiology" ]
151,230	We compared the quality assessment for 2009 using the ATC/DDD indices 2011 and 2019.10,20 To evaluate changes in quality between 2009 and 2017, we used the quartile distribution of the 2009 indicator values as benchmarks for the 2017 values. Only countries able to deliver data for both years were included in this compa...	2	0biomedical	0Study	[ "Pharmacology" ]
271,213	Slowloris, Slow POST, and Slow Next attacks were ineffective against this web server due to the event-driven architecture of the web server. All attacker invalid connections were closed shortly. The web server responded to legitimate users during the attacks without any delay, meaning DoS attacks were unsuccessful. Dis...	1	2other	1Other	[ "Computer Science", "Cybersecurity" ]
92,089	Our study had several additional strengths and limitations. Primary strengths were evaluating the urine LAM assay when used by trained nurses in ambulatory settings, which is similar to a real-world application, assessing both liquid and solid mycobacterial culture as the gold standard, enrolling people prior to HIV di...	4	0biomedical	0Study	[ "Infectious diseases" ]
82,282	For the whole cohort, at the end of week one, a significantly higher proportion of any AE (diarrhoea or nausea or rash) was reported in the amoxicillin group compared to placebo (OR = 1.31, 95% CI 1.05–1.64) (Table 1). The number needed to harm (NNH) was 24, i.e., on average, for every 24 patients receiving amoxicillin...	4	0biomedical	0Study	[ "Pharmacology" ]
52,273	A substantial proportion of the medical issues leading to these calls were classified as “seizures” and this was particularly the case for calls concerning patients aged 1–5 years. As has previously been suggested, this finding might reflect the age-peak of febrile seizures [17, 18]. The results presented in Additional...	4	0biomedical	0Study	[ "Neurology", "Pediatrics" ]
384,277	Complex I (NADH: ubiquinone oxidoreductase) is the largest component of the ETC system, comprising 45 subunits. Electrons, in the form of NADH, enter ETC at Complex I. Complex I is involved as part of the supercomplex consisting of one Complex I, two Complex III, and one Complex IV unit aggregates, which power the prod...	4	0biomedical	0Study	[ "Biochemistry", "Molecular Biology" ]
65,253	Previous murine studies demonstrated prolonged transcription and antigen expression following intramuscular IDLV vaccination, with expression at the site of injection still present at 3 months from the injection.50 It is likely that similar prolonged expression of IDLV delivered antigens in the NHPs was responsible for...	4	0biomedical	0Study	[ "Immunology", "Virology" ]
131,865	Long noncoding RNAs (lncRNAs) are widely conserved sequences longer than 200 nucleotides without protein-coding capacity . As an emerging class of regulatory RNAs, lncRNAs may participate in fundamental processes including cell cycle regulation, proliferation, apoptosis, self-renewal, metastasis and the DNA damage resp...	4	0biomedical	2Review	[ "Molecular Biology", "Oncology" ]
396,249	When the status of the differential methylation sites was confirmed, 4 CpG sites with different degrees of methylation (cg04481923, cg15971518, cg23371584, cg22507406) were selected for cross-validation in blood DNA samples from 30 CR cases and 30 controls, which was in an independent cohort. Thus, each blood DNA sampl...	4	0biomedical	0Study	[ "Epigenetics" ]
54,447	Bartholinitis is quite a common problem in clinical practice and can be caused by a wide variety of micro-organisms . First, Enterobacteriaceae (mainly E. coli) followed by capnophilic species such as Haemophilus influenzae and N. gonorrhoeae . Anaerobic bacteria from the vaginal flora have also been implicated, mostly...	4	0biomedical	1Other	[ "Infectious diseases", "Gynecology" ]
129,081	The extent of LVR is generally believed to be associated with worse long-term clinical outcome along with progression of heart failure (HF). However, whether concomitant diabetes mellitus (DM) is associated with a greater extent of LVR that leads to worse clinical outcome in patients with ST-elevation myocardial infarc...	4	0biomedical	0Study	[ "Cardiology" ]
7,172	CD56bright NK cells are high producers of cytokines and constitute the subtype that predominantly expresses CD62L. Therefore, we evaluated the polyfunctional CD56bright NK cell response induced by a TLR3 agonist in the presence and absence of CD62L expression. We verified that ESN individuals possess CD56bright NK cell...	4	0biomedical	0Study	[ "Immunology" ]
48,450	To evaluate the influence of Ad-MSC on tube formation of HUVEC, the effects of conditioned medium collected from the Ad-MSC/ESCendo and Ad-MSC/ESCcyst cocultures on HUVEC tube formation was studied. Conditioned medium from all three systems induced a significant (P < 0.05) increase in tube formation compared to the unt...	4	0biomedical	0Study	[ "Cell biology", "Tissue engineering" ]
123,713	Grouped and splitted violin-plots of the features for both alive and dead records. (a) Overlap distribution. (b) Retrieval Performance Score distribution. (c) Query scope distribution. (d) Sum TF distribution. (e) Sum TFIDF distribution. (f) LMDirichlet Score distribution. (g) SCQ Score distribution. (h) Clarity Score ...	2	0biomedical	0Study	[ "Bioinformatics" ]
369,860	For osteogenic differentiation, cells were induced by growth in classic MSCs medium supplemented with 10 mmol/L β‐glycerophosphate disodium salt hydrate (Sigma, Cat# G9422), 50 μmol/L l‐ascorbic acid (Med Chem Express, Cat# HYB0166) and 100 nmol/L dexamethasone (Sigma, Cat# D4902). For adipogenic differentiation, the i...	4	0biomedical	0Study	[ "Stem cell biology" ]
281,122	Ten items were prepared to determine students’ attitude towards COVID-19 prevention measures. The items have three alternative options, "Agree", "Neutral", and "Disagree". Two points were provided for those who responded "Agree", one point for "Neutral", and zero points for "Disagree" responses. The mean attitude score...	2	0biomedical	0Study	[ "Epidemiology", "Public Health" ]
57,319	The routinely performed CT scans showed an ostial angulation that reduced the cross-sectional area of the vessel in 3 patients, 2 of whom had LCA proximal angulation with mild stenosis (25–50%) and one of whom had moderate stenosis of the LAD (55%). In the latter case, the ostium of the coronary artery (LAD) was locate...	4	0biomedical	0Study	[ "Cardiology" ]
78,164	Average hyperedge node degree for three discrete age groups in the age-memory study. Regions of relative high node degree are consistent across the three groups, but the overall node degree is about five times larger in the group with ages from 60–75. This corresponds to previous observations of increasing cardinality ...	4	0biomedical	0Study	[ "Neuroscience" ]
369,142	DSEPs that participate in the complement and coagulation cascade pathways account for the largest proportion, that is, the organism may first regulate this pathway to fight S. aureus infection. Thirty upregulated DSEPs, such as coagulation factor (X, VII), complement component (C3, C9) and alpha-2-macroglobulin (A2M), ...	4	0biomedical	0Study	[ "Immunology" ]
129,589	Another manager reflected that there was initially a continuation of face to face work-related meetings in confined spaces at the ward. Retrospectively, these gatherings were not in line with the rapidly changing situation during the pandemic and may have increased the risk of transmission between HCWs. ‘We initially m...	2	1clinical	0Study	[ "Public Health" ]
113,952	The behavioral analysis modeled the number of fish that were found in chambers with higher temperatures (chambers 5 and 6) as a function of the two temperature groups (control WTR and control RTR), the challenge groups (fever and no fever), and their interaction (four groups in total). The Wald test highlight that in t...	4	0biomedical	0Study	[ "Virology", "Immunology" ]
209,409	The ELISA tests were used; for NGF-Human, the NGF ELISA kit was used (My Bio Source, San Diego, CA, USA, Catalog No.: MBS355238); for creatinine, the ELISA kit was used (RnD Systems, Minneapolis, MN, USA, Catalog No.: KGE005). The urinary NGF/creatinine levels were compared among the control, pure OAB, and OAB coexisti...	4	0biomedical	0Study	[ "Urology", "Neurology" ]
381,999	African swine fever outbreaks were reported in South Kivu in 2019 causing mortality in domestic pigs. We report for the first time the complete genome sequence of the ASFV Uvira B53, a genotype X and serogroup 7 strain involved in outbreaks in South Kivu. Its similarity with Kenya 1950 strain based on MGF members sugge...	4	0biomedical	0Study	[ "Virology", "Epidemiology" ]
271,270	GFAP, a type III intermediate filament protein that was discovered by Dr. Eng in 1969 (18, 19), is responsible for the main cytoskeletal structure of astrocytes (19, 20). Apart from being present in the CNS, GFAP is also present in non-myelinated Schwann cells in the peripheral nervous system (PNS) and in enteric glia ...	3	0biomedical	0Study	[ "Neurobiology" ]
113,981	This raises the query-Is this by chance? Does ovarian stimulation for IVF trigger some gene mutation or an underlying microscopic pathology in ovarian cells leading to development of such rapid and aggressive tumor with mortal prognosis in a very short time period?	2	0biomedical	1Other	[ "Reproductive Biology", "Oncology" ]
369,210	The cisternography found that the most frequent level of CSF leakage was the thoracic level. The percentages of patients with CSF leakage at the cervical, thoracic, and lumbar levels were 44.3% (n =132), 51.3% (n = 153), and 21.5% (n = 64), respectively. CSF leakage was undetermined in 45 patients (15.1%). Multiple lea...	4	0biomedical	0Study	[ "Neurology" ]
289,857	Recently, Miccoli et al. proposed a new bending test device able to evaluate the flexibility of NiTi instruments at different length from the tip (i.e., 3, 6 and 9 mm), providing a more representative description of the bending ability of NiTi instruments .	3	0biomedical	0Study	[ "Biomaterials" ]
134,900	1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section...	1	2other	1Other	[ "N", "A" ]
228,353	Previous meta-analyses have found that the infection-fatality ratio (IFR) for COVID-19 varies substantially between locations, with much of the variation attributable to differences in population age structure. Brazeau and colleagues (October, 2020) estimated IFRs of 0·23% for hypothetical populations with the age stru...	4	0biomedical	0Study	[ "Epidemiology" ]

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