Molecule name
stringlengths
9
9
SMILES
stringlengths
22
88
MLM CLint
float64
0
10.4k
E-0011643
Cn1c2ccc(C(=O)NCCO)cc2c2nc3cnccc3cc21
720
E-0011644
Cc1c2ccnc(C(=O)N[C@H](C)CN(C)C)c2cc2c3cc(F)ccc3n(C)c12
1,334.9
E-0011645
Cn1c2ccc(OCCN3CCCCC3)cc2c2ccc(-c3ccncc3)cc21
300.3
E-0011646
O=C1CCc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc2N1
527.7
E-0011647
Cn1c(=O)ccc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc21
210.3
E-0011648
c1cc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc2cn1
1,447.9
E-0011649
C[C@H](N)COc1ccc2c(c1)c1cc3ccccc3nc1n2C
248.4
E-0011650
Cc1c2ccncc2cc2c3cc(Oc4cccnc4)ccc3n(C)c12
893.9
E-0011651
Cn1c2ccc(OCC(N)=O)cc2c2cc3ccncc3nc21
976.8
E-0011652
Cc1c2ccncc2cc2c3ccccc3n(CCN(C)C)c12
1,419.5
E-0011653
Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(F)c(F)cc3n(C)c12
590.4
E-0011654
Cn1c2ccc(OCCN3CCCCC3)cc2c2cc3ccncc3nc21
1,295.3
E-0011655
CN1CCN=C1COc1ccc2c(c1)c1cc3ccccc3nc1n2C
2,503.9
E-0011656
Cn1c2ccc(OCCN3CCCCC3)cc2c2nc3cc(F)c(F)cc3nc21
306.1
E-0011657
Cc1c2ccncc2cc2c3cc(Oc4ccc(N)nc4)ccc3n(C)c12
1,298.2
E-0011658
CN1C(=O)CCc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc21
1,377.7
E-0011659
COc1ccc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc2n1
172.8
E-0011660
c1cc(OCCN2CCCCC2)cc(-c2ccc3ccnnc3c2)c1
1,081.1
E-0011661
c1cc2ccc(-c3ccc(OCCN4CCCCC4)cc3)nc2cn1
500
E-0011662
O=C1Cc2ccc(-c3ccc(O)cc3)cc2N1
364
E-0011663
Oc1ccc(-c2ccc3ccncc3c2)cc1
1,409.5
E-0011664
O=C1Cc2ccc(-c3cccc(O)c3)cc2N1
2,271
E-0011665
CN1C(=O)Cc2ccc(-c3cccc(O)c3)cc21
2,282.9
E-0011666
Oc1cccc(-c2ccc3ccncc3c2)c1
1,433.7
E-0011667
COc1ccccc1Nc1nc(-c2ccc(F)cc2)cs1
1,894.8
E-0011668
CN(C)c1cccc(Nc2nc(-c3ccc(F)cc3)cs2)c1
4,090.6
E-0011669
COc1cc(Nc2nccc(=O)[nH]2)cc(OC)c1
1,559.2
E-0011670
COc1cccc(Nc2nccc(=O)[nH]2)c1
691
E-0011671
Cc1cccc(Nc2nccc(=O)[nH]2)c1
666.4
E-0011672
Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(F)ccc3n(C)c12
597.5
E-0011673
COc1ccc2c(c1)c1cc3cnccc3c(C)c1n2CCN1CCCCC1
1,088.5
E-0011674
Cc1c2ccncc2cc2c3ccccc3n(CC3=NCCN3)c12
205.9
E-0011675
Cc1c2ccncc2cc2c3ccccc3n(CCN3CCCCC3)c12
1,019.7
E-0011676
Cc1c2ccncc2cc2c3ccccc3n(CCN3CCOCC3)c12
1,083.4
E-0011677
Cn1c2ccc(OCCN)cc2c2nc3cnccc3nc21
266
E-0011678
Cn1c2ccc(OCCN3CCOCC3)cc2c2cc3cnccc3nc21
1,400.4
E-0011679
C[C@H](N)COc1ccc2c(c1)c1cc3ccncc3nc1n2C
279
E-0011694
Fc1cc(-c2ccnc(Nc3cccc(CN4CCOCC4)c3)n2)cc(N2CCOCC2)c1
3,063.2
E-0011695
O=C1Cc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc2N1
91.9
E-0011696
CN1C(=O)Cc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc21
881.9
E-0011697
O=C1Cc2ccc(-c3cccc(OCCN4CCCCC4)c3)cc2N1
186.2
E-0011698
c1cc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc2nn1
649.4
E-0011699
c1cc(OCCN2CCCCC2)cc(-c2ccc3ccncc3c2)c1
1,150.7
E-0011700
CN1C(=O)Cc2ccc(-c3ccc(O)cc3)cc21
570.3
E-0011701
Fc1ccc(-c2csc(Nc3ccc4ccccc4c3)n2)cc1
373.7
E-0011702
Fc1ccc(-c2csc(Nc3ccncc3)n2)cc1
264
E-0011703
COc1ccc(Nc2nc(-c3ccc(F)cc3)cs2)cc1
1,608.8
E-0011704
CN(C)c1ccccc1Nc1nc(-c2ccc(F)cc2)cs1
2,771.7
E-0011705
CN(C)c1ccc(Nc2nc(-c3ccc(F)cc3)cs2)cc1
1,234.3
E-0011706
Nc1ccnc2cc(-c3ccccc3)nn12
2,141.8
E-0011753
COc1ccc2c(c1)c1cc3cnccc3c(C)c1n2CCN1CCOCC1
1,379.9
E-0011754
CNCCOc1ccc2c(c1)c1nc3cnccc3nc1n2C
492.4
E-0011755
CNCCOc1ccc2c(c1)c1cc3cnccc3c(C)c1n2C
204.3
E-0011756
C[C@H](N)COc1ccc2c(c1)c1cc3cnccc3nc1n2C
343.6
E-0011757
Cn1c2ccc(OCCN3CCCCC3)cc2c2cc3cnccc3nc21
1,032.7
E-0011758
Cc1cc(-c2nccs2)cc2c3cc(OCCCN4CCCC4)ccc3n(C)c12
1,273.3
E-0011759
CN1C(=O)Cc2ccc(-c3cccc(OCCN4CCCCC4)c3)cc21
814.4
E-0011760
Cc1cc(C2(C#N)CC2)cc2c3cc(OCCCN4CCCC4)ccc3n(C)c12
1,260.2
E-0011761
Cc1cc(C#N)cc2c3cc(OCCN4CCCCC4)ccc3n(C)c12
1,145.5
E-0011762
O=c1ccnc(Nc2cc(Cl)cc(Cl)c2)[nH]1
1,341.7
E-0011763
O=c1ccnc(Nc2cccc(Cl)c2)[nH]1
587.2
E-0011764
CN1CCN=C1COc1ccc2c(c1)c1cc3ccncc3nc1n2C
388.9
E-0011765
Cn1c2ccc(OCCN3CCCCC3)cc2c2nc3cc4c(cc3nc21)OCO4
254.4
E-0011766
Cn1c2ccc(OCC(N)=O)cc2c2cc3cnccc3nc21
2,447.6
E-0011791
CS(=O)(=O)Nc1cccc(-c2ccnc(Nc3ccc(CC(N)=O)cc3)n2)c1
708.9
E-0011802
Cc1cc(C#N)cc2c3cc(Oc4ccnc(N)c4)ccc3n(C)c12
572.8
E-0011803
COCCNC(=O)c1ccc2c(c1)c1cc(C#N)cc(C)c1n2C
753.7
E-0011804
COc1cc(Nc2nc(-c3ccccc3)cc(=O)[nH]2)cc(OC)c1
315.8
E-0011805
Nc1cc(C2CC2)nc2cc(-c3ccccc3)nn12
776
E-0011806
COc1ccc(-c2cc(N)n3nc(-c4ccccc4)cc3n2)cc1
169.2
E-0011807
COc1cccc(-c2cc(N)n3nc(-c4ccccc4)cc3n2)c1
314.9
E-0011808
COC(=O)c1n[nH]cc1Nc1ccccc1
1,096.3
E-0011833
CC(C)c1cc(N)n2nc(-c3ccccc3)cc2n1
4,604.6
E-0011834
C#Cc1cc(N)n2nc(-c3ccccc3)cc2n1
1,488
E-0011835
COc1ccccc1-c1cc2nc(-c3ccccc3)cc(N)n2n1
1,041.1
E-0011836
COC(=O)c1nn(Cc2ccccc2)cc1N
46.7
E-0011837
COC(=O)c1c(N)cnn1Cc1ccccc1
91.2
E-0011838
Cc1cc(-c2cnccn2)cc2c3cc(OCCCN4CCCC4)ccc3n(C)c12
1,125.1
E-0011839
Cc1cc(-c2cncs2)cc2c3cc(OCCCN4CCCC4)ccc3n(C)c12
532.2
E-0011840
Cc1cc(C#N)cc2c3cc(OCCNC4CCC(F)(F)CC4)ccc3n(C)c12
1,019.4
E-0011841
Cc1c2ccncc2cc2c3cc(OCC4CNC4)ccc3n(C)c12
212
E-0011842
Cc1c2ccncc2cc2c3cc(OC4CCNC4)ccc3n(C)c12
374.5
E-0011863
COC(=O)c1n[nH]cc1N(C)C
38.4
E-0011864
Fc1ccc(-c2csc(Nc3cccc(N4CCOCC4)c3)n2)cc1
1,413.3
E-0011865
Nc1cc(-c2ccccc2)nc2c(-c3ccccc3)cnn12
74.6
E-0011866
CCCc1cc(N)n2nc(-c3ccccc3)cc2n1
4,504.6
E-0011867
CN(C)c1cc(-c2ccccc2)nc2cc(-c3ccccc3)nn12
2,393.7
E-0011868
Cc1cc2nc(-c3ccccc3)cc(N)n2n1
2,133.6
E-0011869
COc1ccc(-c2cc3nc(-c4ccccc4)cc(N)n3n2)cc1
257.8
E-0011870
COc1cccc(-c2cc3nc(-c4ccccc4)cc(N)n3n2)c1
600.6
E-0011871
OCCNc1cc(-c2ccccc2)nc2cc(-c3ccccc3)nn12
376.8
E-0011872
O=C(c1n[nH]c2ccccc12)N1CCC(Nc2ccc(Cl)cc2)CC1
166.2
E-0011873
O=C(c1n[nH]c2ccccc12)N1CCC(NCc2ccc(Cl)cc2)CC1
352.8
E-0011874
O=C(c1n[nH]c2ccccc12)N1CCN(Cc2ccc(C(F)(F)F)cc2)CC1
758.4
E-0011875
Cc1c2ccncc2cc2c3cc(OCC4(C)CNC4)ccc3n(C)c12
272.4
E-0011877
Cc1c2ccncc2cc2c3cc(OCC4CCN4)ccc3n(C)c12
382.4
E-0011880
Fc1cccc(-c2ccnc(Nc3ccc(CN4CCOCC4)cc3)n2)c1
2,065.7
E-0011881
c1cc2ccc(-n3cc(OCCN4CCCCC4)cn3)cc2cn1
883.6
E-0011882
c1cc2ccc(-n3cc(OCCN4CCCCC4)cn3)cc2nn1
787.4
E-0011883
CNc1cc2ccncc2cc1-n1cc(OCCN2CCCCC2)cn1
1,504.8