topic stringlengths 245 1.29k | doc stringlengths 52 16.9k | label stringclasses 3
values |
|---|---|---|
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 50.0-75.0, Osteoporosis Prostate Cancer Biopsy-confirmed early stage prostate cancer Disease localized within the capsule No evidence of regional or distant spread (i.e., T1-2, N0, M0 disease) A cohort of patients must have undergone a prior radical prostatectomy Prostate specific antigen < 12 n... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Metastatic Colorectal Cancer Patients must have metastatic colorectal cancer. Patients are eligible whether they are previously untreated or had received prior treatment. 2. Patients must have a source of autologous tumor that can be easily harvested. This includes patients with subc... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 16.0-70.0, Lymphoma Histologically confirmed follicular non-Hodgkin's lymphoma (NHL) High-risk disease, as defined by any of the following Relapsed within 6 months after the last treatment Failed to achieve a complete response during the last treatment Relapsed after prior autologous hematopoiet... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Non-Hodgkin's Lymphoma Chronic Lymphocytic Leukemia Patients with low grade NHL (follicular lymphoma, small cell lymphocytic lymphoma, marginal cell lymphoma, monocytoid B-cell lymphoma, MALT lymphoma, plasmacytoid lymphocytic lymphoma) or chronic lymphocytic leukemia who have demons... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, B-Chronic Lymphocytic Leukemia Diagnosis of B-CLL (no mantle cell) Must have active disease Age >=18 yo ECOG 0-3 No radiation or surgery <4 weeks Any of the following comorbid conditions New York Heart Association Class III or IV heart disease Recent myocardial infarction (<1 month)... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphoma, B-Cell Relapsed or refractory B-Cell NHL Histological documentation of diffuse large B-cell lymphoma, follicular lymphoma (grade 1, 2, or 3), small lymphocytic lymphoma or transformed B-Cell lymphoma Bi-dimensionally measurable disease with at least one lymph node or tumor ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 15.0-80.0, Leukemia, Lymphocytic, Chronic, B-Cell Patients with histologically or cytologically confirmed CLL Patients with hemoglobin concentration and/or platelet count below the institution's lower limit of normal Patients who have not received cancer chemotherapy or radiotherapy Patients wi... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia B-cell Leukemia Chronic Leukemia Chronic Lymphocytic Leukemia (CLL) ≥ age 18 Karnofsky performance status 60% or above Confirmed immunohistological diagnosis of Chronic Lymphocytic Leukemia (CLL) Rai Stage I to IV as follows Advanced stage disease (Rai Stage III or IV, or mo... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 3.0-999.0, Cutaneous Leishmaniasis Presentation: At least 1 lesion must be ulcerative. Parasitology: Parasitological confirmation of 1 lesion will be made by visualization or culture of leishmania from the biopsy or aspirate of the lesion. Previous RX: No specific or putatively specific therapy ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Prostatic Neoplasms Patients with clinical stage T1-T4 carcinoma of the prostate Must have undergone radical radiation and at least 2 years of Pharmacological androgen ablation.Pharmacological androgen ablation may LHRH-agonists with or without Non-steroidal androgen ablation, Steroi... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia Confirmed diagnosis of chronic lymphocytic leukemia (CLL) Stage 0, I, or II disease Previously untreated disease Splenomegaly, hepatomegaly, or lymphadenopathy are not required for the diagnosis of CLL Absolute lymphocyte count > 10,000/mm^3 Lymphocytosis must consist of sma... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 15.0-999.0, Leukemia Diagnosis of B-cell chronic lymphocytic leukemia meeting 1 of the following Previously treated stage III or IV or earlier stage disease with evidence of active disease, as defined by ≥ 1 of the following Weight loss > 10% within the past 6 months Extreme fatigue Fever or nig... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Hepatic Encephalopathy Hepatitis C Liver Cirrhosis Phase A Subject is 18 to 70 years of age, inclusive Subject has cirrhosis due to chronic HCV infection as documented by Subject has evidence of hepatic encephalopathy as evidenced by Neuro-psychometric Testing (Number Connection Test,... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia Diagnosed B-cell chronic lymphocytic leukemia (CLL) defined by the National Cancer Institute (NCI) Working Group Meets 1 of the following Binet stage C disease Binet stage B disease AND ≥ 1 of the following signs or symptoms* B symptoms (night sweats, weight loss ≥ 10% withi... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Prolymphocytic Leukemia Diagnosis of B-cell prolymphocytic leukemia Previously treated disease All Binet stages allowed Life expectancy > 3 months ECOG/WHO performance status 0-3 PRIOR No more than 3 prior treatment regimens | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia, Lymphocytic, Chronic Patients must have a histologic diagnosis of CLL as defined by the WHO and exhibit active disease requiring treatment as per the NCI working group on CLL. 2. Patients must have a fresh tumor specimen available (peripheral blood or bone marrow) for flow ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia, Lymphocytic, Chronic Ages 18 years and older Diagnosis of CLL established by peripheral blood and bone marrow examination and using the standard Patients with Rai stage III or IV, or earlier stage with massive, symptomatic lymphadenopathy requiring therapy Primary resistanc... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 16.0-60.0, Lymphoma Confirmed diagnosis of previously untreated large B-cell Non Hodgkin's, Large Cell Lymphoma and B-Cell with high grade features. Other aggressive lymphomas such as Primary Mediastinal large B-cell Lymphomas will be also allowed to be included. 2. Patients with performance sta... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Acute Myocardial Infarction patients with acute Myocardial infarction with ST elevation , and moving by ambulance to Poriya hospital women less than 50 years old and 80 years old, bleeding tendency, stroke in the past | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Prostatitis Pelvic Pain Male subjects aged 18 and older. 2. Male subjects with at least 3 months of symptoms of CP/CPPS who are refractory to other therapies 3. Subjects with a minimum score of 15 on the CPSI. 4. Male subjects must give written informed consent. 5. Male subje... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Refractory Chronic Lymphocytic Leukemia Stage I Chronic Lymphocytic Leukemia Stage II Chronic Lymphocytic Leukemia Stage III Chronic Lymphocytic Leukemia Stage IV Chronic Lymphocytic Leukemia Histologically or cytologically confirmed chronic lymphocytic leukemia (CLL) by NCI-WG immun... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Confirmed diagnosis of previously treated chronic lymphocytic leukemia (CLL) meeting the following Binet stage B (Rai stages I and II) or Binet stage C (Rai stages III and IV) disease Rapid disease progression, symptomatic enlarged lymph nodes, or severe ... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hypercholesterolemia Patients are eligible for study entry based on the following 1. Males or females greater than or equal to 18 years of age 2. Females must not be pregnant or lactating. Females of childbearing potential and males must use a reliable means of contraception. 3. LDL-... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, B-Cell Chronic Lymphocytic Leukemia (B-CLL) A diagnosis of B-cell chronic lymphocytic leukemia (B-CLL); according to the National Cancer Institute Working Group (NCI WG) Criteria World Health Organization (WHO) performance status of 0, 1, or 2 Life expectancy ≥ 12 weeks Previous ther... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-85.0, T-LGL Lymphoproliferative Disorders Clinical history supportive of the diagnosis of T-LGL leukemia (i.e. a history of cytopenias with peripheral blood morphologic evidence of LGLs) Immunophenotypic studies of peripheral blood showing an increased population of T-LGLs (suggested by sta... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 12.0-60.0, Cutaneous Leishmaniasis Parasitologically proven cases of CL based on positive smear and/or culture Otherwise healthy subjects on the basis of medical history, physical examination and results of blood test (if seemed necessary by the physician) Age 12-60 years Willing to participate ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Astrocytoma Glioma Oligodendroglioma Patients must have histological or neuroradiographic documented recurrent glioma defined as an anaplastic astrocytoma, mixed malignant glioma or oligodendroglioma. All patients must have had prior pathologic confirmation of primary tumor histology... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Leukemia Lymphoma Diagnosis of CLL, Small lymphocytic lymphoma (SLL), or -cell prolymphocytic leukemia (T-PLL). 2. Previously treated with chemotherapy or monoclonal antibodies. 3. All patients with Rai stage III-IV are eligible Patients with Rai stage 0-II who meet one or more indica... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-60.0, Renal Transplant primary renal transplant (not HLA identical) ages 18-60 years recipient panel reactive antibody level >10% recipient of a DCD kidney no prior organ transplant no multi-organ transplant recipient no subject who is currently receiving systemic corticosteroids no pregna... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 21.0-99.0, Refractory Chronic Lymphocytic Leukemia Patients diagnosed with Chronic Lymphocytic Leukemia Prior therapy with fludarabine or a fludarabine containing regimen CD20 expression on CLL cells Neutrophil count ANC greater than 500/mm(3) Platelet count greater than 30K/mm(3) Age 21-99 Bul... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cytopenia acute leukemia receiving remission induction chemotherapy receiving antibiotic prophylaxis for cytopenia leukocytes lower than 1000/mm3 in peripheral blood) informed consent none | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Chronic Lymphocytic Leukemia Untreated CLL, CLL/PLL, or SLL (small lymphocytic lymphoma) with indication for therapy. Indications for therapy at least one of the following: (1) one or more disease-related symptoms [fever, night sweats, weight loss > 10% in prior 6 months, pronounced f... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Signed, written EC-approved informed consent form Diagnosis of relapsed CD23+ and CD20+ B cell CLL as defined by NCI WG guidelines Subjects who have received at least 1 but no more than 2 prior single agent or combination treatments for CLL Rai Stage III ... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Multiple Myeloma Lymphoma, Non-Hodgkin's (Abbreviated List) Diagnosis of non-Hodgkin's lymphoma (NHL) or multiple myeloma (MM) Eligible for autologous transplantation <=3 prior regimens of chemotherapy (Rituxan is not considered chemotherapy for the purpose of this study) >4 weeks sin... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cystic Fibrosis Phlebitis Diagnosis of cystic fibrosis, made accordingly to the Cystic Fibrosis Foundation Guideline (Rosenstein BJ. J Pediatr 1998;132: 589-595) age of 18 years or more and ability to consciously express owns informed consent have a prescription done by one of the CF... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Diabetes Mellitus, Type 2 Patients with type 2 diabetes mellitus Having been treated with any other insulin, but who did not reach the target of A1c=7% Ability and willingness to perform Self Monitoring Blood Glucose measurement Will follow the prescribing information (Summary of Pr... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Polycythemia Vera Essential Thrombocytosis Idiopathic Myelofibrosis Neutrophils Chronic Myeloproliferative Disorders Diagnosis or suspected diagnosis of PV, ET, or IMF. The World Health Organization will be used for diagnosing this disorder. In brief, the for PV is hemoglobin greater... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-120.0, Leukemia Lymphoma Lymphoproliferative Disorder Biopsy-proven* relapsed or refractory lymphoma, including the following Aggressive lymphoma (closed to accrual as of 2/7/08 except for diffuse large B cell lymphoma, grade III follicular lymphoma, or transformed lymphoma) Transformed lym... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 21.0-999.0, Chronic Lymphocytic Leukemia (CLL) Small Lymphocytic Lymphoma Diagnosed with chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL). 2. Failed prior standard of care therapy for CLL. 3. Neutrophil count (ANC) greater than or equal to 500/microliter (mcL). 4. Platelet ... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Advanced CLL, defined as no response or progressive disease during standard nucleoside analogue based regimen; or, evidence of progressive disease within 24 months of completion of nucleoside analogue regimen; or, intolerance to fludarabine; or, failure t... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Melanoma (Skin) Histologically confirmed primary melanoma of cutaneous origin Stage II (T3 N0 M0 1.5-4.0mm Breslow depth Clinically negative regional lymph node pathologic status unkown OR Histologically negative regional lymph nodes Stage III (T4 N0 M0) Greater than 4.0mm Breslow de... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Chronic Lymphocytic Leukemia Diagnosis of B-cell CLL Relapsed, fludarabine-sensitive (duration of response > 6 months as assessed by prior treating physician) or fludarabine-naive patients Rai Stage III or IV, or Rai Stage I or II if determined to have disease progression as evidenced... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia Histologically or cytologically confirmed Richter's transformation, fludarabine-refractory chronic lymphocytic leukemia or prolymphocytic leukemia. 2. Patients must be 18 years of age or older. 3. Patients must have a performance status of 0-2 (Zubrod scale). 4. Patients mus... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Kidney Cancer Histologically or cytologically confirmed renal cell carcinoma (any histology) based on prior biopsy or biopsy performed and reviewed at Cleveland Clinic Foundation. This can pathology read as adenocarcinoma consistent with renal origin Unresectable primary tumor due to... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hepatocellular Carcinoma Age > 18 years ECOG PS 0-2 Histologically or cytologically documented unresectable and/or metastatic HCC Measurable disease by criteria Previous local therapy completed > 6 weeks Any acute toxicity (CTC-AE) < grade 1 Child-Pugh A Liver transaminases ≤ 5 x ULN... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Richter's Transformation Leukemia All patients with histologically or cytologically confirmed Richter's transformation, prolymphocytic leukemia, aggressive, or relapsed/refractory B-cell chronic lymphocytic leukemia are eligible for this protocol Patients must be 18 years of age or o... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 45.0-90.0, Lung Diseases Bronchitis, Chronic Male or female out-patients >/= 45 years Subjects suffering from chronic bronchitis FEV1</= 70% and FEV1/FVC </= 70% predicted from age, height and sex No documented episode of AECB (requiring treatment) within 6 weeks of randomization and not experie... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 50.0-999.0, Osteoporosis Postmenopausal women at or above the age of 50, diagnosed with primary osteoporosis may be enrolled in the trial if the following inclusion/ apply. All must be answered "yes" for a subject to be enrolled in the trial. 1. Has the subject given informed consent according ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Lymphoma; Large Cell (Diffuse) With Small Cell, Diffuse aggressive non-Hodgkin lymphoma b cells age 18-70 bilirubin less then 2 creatinine less then 2 Pet/CT performed post 2 cycles no PET/CT post 2 cycles performed bilirubin >2 creatinine more then 2 HIV positivity | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Prostate Cancer Patient must have androgen independent Stage IV prostate cancer, with anaplastic features as defined by at least one of the following: a) Histologic evidence of small cell(pure/mixed), locally advanced or metastatic; b) Any of the following at Dx: exclusive visceral m... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Melanoma Histologically confirmed diagnosis of melanoma Progressive disease that is not surgically resectable, or metastatic Stage IV Low-normal LDH, defined as ≤ 0.8 times the upper limit of normal No prior chemotherapy Measurable disease ECOG performance status ≤ 1 At least 4 weeks... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, Diffuse Large B Cell Lymphoma Age 18-65 years Diagnosis of Diffuse Large B-Cell Lymphoma Adverse Prognosis = Stage 3 or 4 and elevated LDH No more than one prior cycle of R-CHOP chemotherapy Adequate cardiac function No central nervous system involvement by lymphoma Histological diag... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Chronic Heart Failure Patients That Have Received a Left Ventricular Assist Device Patients that have had a left ventricular assist device (LVAD) implanted for chronic heart failure, where chronic heart failure is defined as at least 6 months Patients are clinically stable in the opin... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, Cutaneous Leihmaniasis Gender: Male Age: Adults Presentation: At least 1 lesion must be ulcerative. Parasitology: Parasitological confirmation of 1 lesion will be made by visualization or culture of leishmania from the biopsy or aspirate of the lesion Previous treatment for leishmani... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-100.0, HIV Infections Under this protocol, cell recipients must fulfill all of the following characteristics and conditions: Greater than or equal to 18 years old Ability to sign informed consent For women of child-bearing potential, negative result on a serum or urine pregnancy test; in ad... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Recurrent Skin Cancer Squamous Cell Carcinoma of the Skin Stage 0 Chronic Lymphocytic Leukemia Stage I Chronic Lymphocytic Leukemia Diagnosis of 1 of the following Histologically or cytologically confirmed squamous cell carcinoma of the skin Unresectable or metastatic disease Squamou... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, Leukemia Diagnosis of B-cell chronic lymphocytic leukemia (CLL), meeting the following Binet classification stages B or C Del 17 p (FISH) negative (< 10 % positives cores) Matutes score 4 or 5 Transformation to aggressive B-cell malignancy (e.g. diffuse large cell lymphoma, Hodgkin ly... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 6.0-999.0, Hemophilia B Patients with moderate to severe hemophilia B ( < 5% circulating factor IX activity) having acute hemorrhage or requiring "short-term therapy" for intermittent secondary prophylaxis regimens. 2. HIV seropositive ( asymptomatic) or seronegative subjects. 3. No history or d... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Enrollment in this study is open to patients 18 years of age with confirmed chronic lymphocytic leukemia, a clinical response of stable disease or better to previous treatment, and an Eastern Cooperative Oncology Group performance status of 0-2 Treatment... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 19.0-999.0, Traumatic Complication of Injury Adult patient 19 years and older Sustained trauma injuries with Injury Severity Score greater than 9 Under 19 years of age Prisoners Pregnancy Unwilling or unable to give informed consent | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Stage I Chronic Lymphocytic Leukemia Stage II Chronic Lymphocytic Leukemia Stage III Chronic Lymphocytic Leukemia Stage IV Chronic Lymphocytic Leukemia Specific diagnosis of B-cell CLL An absolute lymphocytosis of > 5,000/uL Morphologically, the lymphocytes must appear mature with < ... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphocytic Leukemia Mantle Cell Lymphoma Have histologically or cytologically confirmed CD5+/CD20+ B-Cell Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma Meet the following CLL to participate in this study Absolute lymphocyte count > 5000/μL CD20+ and CD5+ Atypical cells repres... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Osteoarthritis The subject is scheduled to undergo elective total knee replacement at Duke University Hospital The subject has signed the written consent form Known allergy to ropivacaine or hydromorphone Known history of narcotic abuse or alcohol abuse Known history of chronic pain ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Patients should have completed their chemotherapy 3 months prior to start of treatment with lenalidomide and not more than 9 months prior to treatment initiation. 2. Patients with CLL/Small Lymphocytic Lymphoma (SLL) that achieve a complete or stable part... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphoma, Small Lymphocytic Leukemia, Lymphocytic, Chronic Patients with a diagnosis of CLL/SLL who have received at least one prior treatment regimen and have persistent disease (i.e. any evidence of active disease). Patients with a chromosome 17 abnormality or a p53 mutation of any... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-50.0, Tuberculosis Subject is willing and able to give informed consent for participation in the study Male or Female, aged 18 to 50 years In good health BCG-naïve Screening elispot negative (less than 17 spot forming cells per million PBMC) for ESAT 6 and CFP 10 peptide pools Resident in o... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hepatic Encephalopathy Must sign an Informed Consent Form In remission from past HE Appropriate birth control measures More than or equal to 18 years of age Must be potential for benefit from treatment Recent HE episodes Capable and willing to comply with all study procedures Partici... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hodgkin's Disease Lymphoma Histologic diagnosis of Classical Hodgkin lymphoma, confirmed by the department of hematopathology at MSKCC. Patients who have relapsed after an autologous stem cell transplant must have a biopsy after transplant to confirm relapsed Hodgkin's disease. Patie... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia Chronic Lymphocytic Leukemia Patients must have a diagnosis of chronic lymphocytic leukemia and must be previously treated with at least one prior treatment regimen, including a purine-analogue based treatment. 2. Patients must be Rai Stage III or IV OR Rai Stage 0-II and ha... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, Anaplastic Large Cell Lymphoma Cutaneous B-cell Non-Hodgkin Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Intraocular Lymphoma Nodal Marginal Zone B-cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Grade III Lym... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 7.0-999.0, Hereditary Elliptocytosis (HE) Hereditary Pyropoikilocytosis (HPP) > 7 years of age Consenting family members Anyone not meeting the above | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 2.0-17.0, Growth Hormone Deficiency Turner Syndrome Chronic Renal Failure Small for Gestational Age Already treated patients who are dissatisfied with their current self-injection device, or naïve pediatric patients, in cases for which this indication is validated (growth hormone deficiency, Tur... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukaemia Understand and voluntarily sign an informed consent form Age ≥18 years at the time of signing the informed consent form Able to adhere to the study visit schedule and other protocol requirements A confirmed diagnosis of B-cell CLL by NCI Working Group No... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Postoperative Pain Splenomegaly 15 cm or longer spleens Patient confirmation to join the study Normal sized spleens Patient denial | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Confirmed diagnosis of B-cell chronic lymphocytic leukemia (CLL) meeting 1 of the following Binet stage C disease or stage B or A disease requiring treatment Binet stage B or A disease meeting ≥ 1 of the following B-symptoms (e.g., night sweats, weight lo... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Subjects must have a diagnosis of B cell CLL including Lymphocytosis of monoclonal B-cells co-expressing ≥ one B-cell marker (CD19, CD20, or CD23) and CD5 in peripheral blood or lymph node AND Bone marrow with ≥ 30% mononuclear cells having the CLL/SLL ph... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Thyroid Cancer Lymph Node Metastasis Patient diagnosed to have differentiated thyroid carcinoma and has no detectable cervical lymphadenopathy Previous neck surgery, pregnancy and known hypersensitivity to the dye used | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 16.0-999.0, Chronic Lymphocytic Leukemia 16 years or older 2. Untreated CLL with indication for therapy or minimally treated (e.g. less than 1 month of steroids or chemotherapy) are eligible 3. Performance status of 3 or better (Appendix A) 4. Adequate renal and hepatic function (creatinine <2 m... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, B-Cell Chronic Lymphocytic Leukemia Male or female, at least 18 years old Signed informed consent Zubrod performance status of 0, 1, or 2 (Appendix C) Patients with CLL, CLL/PLL or PLL (prolymphocytic) who have achieved a clinical complete remission by NCI-WG with chemotherapy, eg., ... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Head And Neck Cancer Part 2. Patient is initiating radiation therapy for newly diagnosed head and neck cancer 2. Part 2. Patient has an Eastern Cooperative Oncology Group performance status score of 2 or less 3. Part 2. Patient has a spouse or significant other with whom he/she resid... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia Lymphoma Diagnosis of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) Any stage disease Prior histological documentation of CD20+ CLL or SLL Has undergone autologous or syngeneic stem cell transplantation comprising high-dose therapy with peripheral bl... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia and outpatients suffering from CLL, who are treated with Mab Campath, and are routinely monitored with PCR (Polymerase Chain Reaction) for CMV infection during MabCampath treatment and for at least 2 months following completion of treatment In accordance... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 5.0-999.0, Sickle Cell Disease Hemolytic Anemia Established Diagnosis of Hemolysis Sickle Cell Disease (e.g., HbSS, HbS/β-thalassemia, HbSC) Other conditions with hemolysis (e.g., RBC membranopathies, enzymopathies, unstable hemoglobinopathies, PNH) 2. Age SCD participants: 5 years of age up to ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Diagnosis of B-cell CLL/SLL including Lymphocytosis of monoclonal B-cells co-expressing ≥ one B-cell marker (CD19, CD20, or CD23) AND CD5 in peripheral blood or lymph node AND Bone marrow with ≥ 30% mononuclear cells having the ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Diagnosis of B-cell CLL/SLL including Lymphocytosis of monoclonal B-cells co-expressing ≥ one B-cell marker (CD19, CD20, or CD23) and CD5 in peripheral blood or lymph node AND Bone marrow with ≥ 30% mononuclear cells having the ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Leukemia Diagnosis of B-cell chronic lymphocytic leukemia (CLL)*, as defined by the following Peripheral blood absolute lymphocyte count > 5,000/mm³ Small to moderate-size lymphocytes with < 55% prolymphocytes, atypical lymphocytes, or lymphoblasts Phenotypically characterized B-CLL ... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-45.0, Healthy Is the individual a healthy, normal adult man who volunteers to participate? Is he 18-45 years of age, inclusive? Is his BMI ≤30? Is he considered reliable and capable of understanding his responsibility and role in the study? Has he provided written informed consent? A no ans... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-80.0, Chronic Lymphocytic Leukemia B-CLL confirmed according to NCI CLL relapsed or refractory to prior antineoplastic therapy Signs of progressive disease; at least one B symptoms lymphocyte doubling time of < 6 months symptomatic lymphadenopathy or splenomegaly cytopenias due to bone marr... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma A diagnosis of CLL or SLL based on iwCLL diagnostic criteria Prior therapy for CLL (no limit on number of prior regimens) Patients requiring therapy, based on at least one of the iwCLL criteria years of age or older Performance ... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Neuroblastoma Bone Marrow, Sympathetic Nervous System Diagnosis of NB as defined by international i.e., histopathology (confirmed by the MSKCC Department of Pathology) or bone marrow metastases plus high urine catecholamine levels High-risk NB as defined by risk-related treatment guid... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphadenopathy patients 18 years or older 2. Patients in which EBUS is indicated based on the suspicion of either benign or malignant disease in mediastinal and/or hilar lymph nodes. This will patients who are in the hospital patients under 18 years or younger | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Patients undergoing routine blood draws as part of their ongoing follow-up for Chronic Lymphocytic Leukemia (CLL) at the Norris Cotton Cancer Center of DHMC Patients who have received cytotoxic drug, oral or intravenous steroid or targeted antibody thera... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Chronic Lymphocytic Leukemia Age 18-75 years at the time of signing the informed consent form. 2. Disease: CLL in relapse, after failing conventional chemo-antibody combination therapy; CLL patients who failed to achieve CR with frontline conventional chemo-antibody; CLL patients with... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-120.0, Leukemia Stored frozen viable cells from patients with chronic lymphocytic leukemia treated on clinical trial ECOG-2997 Not specified PRIOR Not specified | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Hepatic Encephalopathy Diagnosis of hepatic cirrhosis based on biopsy, clinical and/or radiological findings Stable HE (chronic): On daily lactulose for more than 6 months without hospitalization for HE within 3 months of enrollment Treated with lactulose on a daily basis, with restor... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-90.0, Lung Cancer Sarcoidosis Tuberculosis years old and older Hilar and/or mediastinal lymphadenopathy (> 1 cm on the short axis, as assessed by contrast-enhanced CT scan (computed tomography)) Uncontrolled coagulopathy Refusal to sign informed consent | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Stage I Chronic Lymphocytic Leukemia Stage I Small Lymphocytic Lymphoma Stage II Chronic Lymphocytic Leukemia Stage II Small Lymphocytic Lymphoma Stage III Chronic Lymphocytic Leukemia Stage III Small Lymphocytic Lymphoma Stage IV Chronic Lymphocytic Leuk... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hairy Cell Leukemia One of the following: 1. Patients who previously received CAT-3888 and did not have unacceptable toxicity 2. Patients who received CAT 8015 in study CAT 8015-1001 and have progression of disease or relapse. These patients must be considered off-study for CAT-8015 ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Isolated Mediastinal Lymphadenopathy Sarcoidosis Tuberculosis Lung Cancer Lymphoma Consecutive patients with undiagnosed mediastinal lymphadenopathy (>1cm in short axis) on CT or PET-CT scan for whom pathological evaluation is clinically indicated Patients without informed consent, ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-120.0, Lymphocytic Leukemia Diagnosis of CLL manifested by minimum threshold peripheral lymphocyte count of > 5 x 10^9/L (CLL variant) OR palpable adenopathy >= 1cm or clinically palpable splenomegaly (SLL variant); AND immunophenotypic demonstrations of a population of B lymphocytes (as de... | 2 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.