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This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Adhesive Capsulitis of the Shoulder patients must be diagnosed as having idiopathic adhesive capsulitis in the 'frozen' or 'thawing' phase of disease and have tried and failed at least 3 months of nonoperative therapy. OR patient with adhesive capsulitis who presents already in the 'f... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Eastern Cooperative Oncology Group performance status of 0-1 Diagnosis of chronic lymphocytic leukemia (CLL)/ small lymphocytic lymphoma (SLL) that meets protocol-defined Laboratory values within protocol-defined parameters Acti... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Key Documented diagnosis of B-cell CLL, with diagnosis established according to International Workshop on Chronic Lymphocytic Leukemia (IWCLL) No prior therapy for CLL other than corticosteroids for disease complications CLL that warrants treatment Presen... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 40.0-65.0, Adult Lymphoblastic Lymphoma Disease ALL in complete remission (CR) at the time of transplant. Remission is defined as "less than 5.0% bone marrow lymphoblasts by morphology," as determined by a bone marrow aspirate obtained within 2 weeks of study registration Philadelphia chromosome... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Breast Cancer Nos Metastatic Recurrent Women Aged 18 years and over With an invasive breast cancer diagnosed by cytology or histology Tumors cT0 to cT3, CN0-3 No clinical evidence of metastasis at the time of Untreated including scored for breast cancer surgery in progress Patient re... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Thyroid Cancer Newly diagnosed with a first occurrence of thyroid cancer <2-4 weeks of diagnosis (i.e., histologically confirmed thyroid cancer (papillary, follicular, or medullary type; TNM classification system) Willing to participate in the EG meetings >18 years Alert and capable ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, Chronic Pain Women Clinical diagnosis of chronic pelvic pain More than eighteen years Non-menstrual or noncyclic pelvic pain Duration of pain of at least 6 months Duration of pain less than 6 months Women who were pregnant in the last 12 months | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Coronary Artery Stenosis Age ≥ 18 years Patient with an indication for PCI including angina (stable or unstable), silent ischemia (in absence of symptoms a visually estimated target lesion diameter stenosis of ≥70%, a positive non-invasive stress test, or FFR ≤0.80 must be present), ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphocytic Leukemia, Chronic Adults >/=18 years Documented Cluster of Differentiation Antigen 20 (CD20) + B-Cell Chronic Lymphocytic Lymphoma (B-CLL) Previously untreated Chronic Lymphocytic Leukemia (CLL) requiring treatment according to the National Cancer Institute (NCI) Total Cu... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Refractory Ascites Hepatic Hydrothorax Hepatic Encephalopathy Cirrhosis Cirrhosis (any etiology) Refractory ascites or hepatic hydrothorax and plan for TIPS placement Well-documented overt hepatic encephalopathy, either persistent or at the time of screening Any contraindication for ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-130.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Richter's Syndrome Prolymphocytic Leukemia Men and women ≥ 18 years of age with a confirmed diagnosis of CLL/SLL, which has relapsed after, or been refractory to, ≥ 2 previous treatments for CLL/SLL. 2. Must have measurable CLL/... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Anemia Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Diagnosis of CLL according to the National Cancer Institute (NCI)/Internal Workshop on Chronic Lymphocytic Leukemia (IWCLL) or small lymphocytic lymphoma (SLL) according to the World Health Organization (WHO) criteria; thi... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Non-Hodgkin's Lymphoma B-Cell ALL B-Cell CLL Group A: CD19+ B-ALL undergoing allogeneic HSCT or Group B: CD19+ B cell CLL or NHL undergoing allogeneic HSCT Life expectancy of ≥12 weeks Patient has an appropriate donor identified for hematopoietic stem cell transplantation Any patient ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Multiple Myeloma Patient ≥ 18 years old Patient is, in the investigator(s) opinion, willing and able to comply with the protocol requirements Patient has given voluntary written informed consent before performance of any study-related procedure not part of normal medical care, with t... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Age 18 years or older Diagnosed CD20+ B chronic lymphocytic leukemia (CLL) according to National Cancer Institute (NCI) Active disease meeting at least 1 of the International Workshop on CLL (IWCLL) 2008 for treatment Refractory CLL (i.e. treatment failur... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cardiovascular Disease Patients older than 18 years Literate Patient who agreed to participate in the study by signing the consent form at least 24 hours prior to surgery Patients with a history of surgery Patients in preoperative cardiac transplantation Patients who did not have at... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Tinnitus years of age History of chronic subjective tinnitus that cannot be attributed to vascular, neurologic, neoplastic or traumatic causes Capable of self-applying the lidocaine patches History of heart disease History of irregular heartbeat Prior MI Previous exposure to lidocai... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 40.0-70.0, HIV Infection documented HIV infection between 40 and 70 years of age clinically stable HIV disease as evidenced by a CD4+ T lymphocyte count of > 250 cells/mm3 platelet count between 150,000 and 400,000 cells/mm3 to reduce bleeding risks associated with omega 3-fatty acids treatment ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Cytopenia Patients with hematologic malignancies who have been subjected to allo-HSCT and that are diagnosed with one or more peripheral cytopenias with complete chimerism in bone marrow (determined by molecular-STR-studies). They may 1. Patients who have received as a source of cells... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Participants must meet the following on screening examination to be eligible to participate in the study Subjects must have CLL / SLL, as documented by a history at some point of an absolute peripheral blood B cell count > 5000,... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Richter's Transformation Richter's Transformation, arising in the setting of prior CLL, documented by histologically confirmed lymphoma, including large B-cell and immunoblastic variants All patients must have received at least one prior regimen for CLL, including cytotoxic chemother... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 50.0-80.0, Muscle Atrophy Quality of Life Age: between 50-80 years Primary TKA surgery Previous TKA and/or total hip arthroplasty surgery (older subjects). 2. Dementia or related mental issues that may potentially put the subject at risk as determined by the surgeon. 3. Untreated endocrine dise... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Liver Cirrhosis Signed written informed consent Dignosis of liver cirrhosis (clinical or by liver biopsy) Admission due to variceal bleeding occurred 5 to 42 days prior and standard treatment for secondary prophylaxis failed Confirmed splenorenal shunt, gastrorenal shunt or paraesopha... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia confirmed diagnosis of CLL or SLL previously treated by low dose FCR for active disease requiring treatment per IWCLL dose reduction of fludarabine and cyclophosphamide due to age, comorbid conditions, or reduce creatinine clearance patients treated with... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Ann Arbor Stage III Small Lymphocytic Lymphoma Ann Arbor Stage IV Small Lymphocytic Lymphoma Recurrent Chronic Lymphocytic Leukemia Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia Refractory Small Lymphocytic Lymphoma Stage III Chronic Lymphocytic Leukemi... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Metastatic Pancreatic Adenocarcinoma Stage III Pancreatic Cancer AJCC v6 and v7 Stage IV Pancreatic Cancer AJCC v6 and v7 Unresectable Pancreatic Carcinoma PHASE I STUDY - ARM A (DOSE LEVEL 1) AND ARM B (DOSE LEVEL 2) Patients must have histologically or cytologically confirmed metas... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Chronic Lymphocytic Leukemia Clinical and phenotypic verification of B cell CLL and measurable disease. Immunophenotyping of the leukemic cells must demonstrate a monoclonal B cell population with immunophenotype consistent with CLL Relapsed or refractory disease, defined by failure t... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 16.0-999.0, Cellulitis Age >16 years Suitable for treatment with flucloxacillin 500mg -1gram qds monotherapy or a suitable alternative for penicillin allergic patients as listed in the local prescribing guidelines Appearance of typical, plaque-like area of erythema over any body part excluding t... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocyte Leukemia Adult Patients 18 years of age or older. 2. Diagnosis of CLL meeting IWCLL criteria. 3. The diagnosis of CLL requires a history of lymphocytosis with a B-lymphocyte count ≥5,000/μL. Prolymphocytes may comprise no more than 55% of blood lymphocytes. 4. Acti... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, Chronic Lymphocytic Leukemia Leukemia Must have a confirmed diagnosis of chronic lymphocytic leukemia or small lymphocytic lymphoma. as per IW-CLL 2008 criteria. Patients must also require therapy for that diagnosis, based on meeting at least one of the following evidence of progressi... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Myelodysplastic Syndromes Completion of the treatment period in the base study A536-03 (ClinicalTrials.gov Identifier: NCT01749514) Adequate birth control measures Patient is able to adhere to the study visit schedule, understand and comply with all protocol requirements Patient unde... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Prolymphocytic Leukemia Recurrent Mantle Cell Lymphoma Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia Richter Syndrome World Health Organization (WHO)/Eastern Cooperative Oncology Group (ECOG) performance status =< 2 Life expectancy >= 2 months Appropria... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Hodgkin Disease Non-Hodgkin Lymphoma Severe Chronic Active Epstein Barr Virus T/NK-lymphoproliferative Disease Nasopharyngeal Carcinoma Smooth Muscle Tumor Any patient regardless of age or sex, with diagnosis of either EBV positive Hodgkin's lymphoma EBV Positive non-Hodgkin's Lymphom... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Prolymphocytic Leukemia Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia A histologically confirmed diagnosis of CLL according the International Workshop on CLL/SLL/B-cell PLL or va... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Monoclonal B-Cell Lymphocytosis Stage 0 Chronic Lymphocytic Leukemia Stage I Chronic Lymphocytic Leukemia Stage I Small Lymphocytic Lymphoma Diagnosis of: 1. CLL according to the National Cancer Institute (NCI) 2. Small lymphocytic lymphoma (SLL) according to the World Health Organiz... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Advanced Solid Tumors Chronic Lymphocytic Leukemia Advanced solid tumors likely to have alterations in DNA repair mechanisms, such as the BRCA and ATM pathways, or CLL, with no other standard surgical, radiation, or systemic anticancer therapies available. Subjects with CLL will be e... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leucemia Diagnosis of CLL in need of treatment according to the iwCLL guidelines 2. Relapsed or refractory disease after at least one, but no more than 3 prior regimens for CLL 3. Medically fit patients without relevant comorbidity, defined as total CIRS score ≤6 ... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lung Cancer Patients must have histologically or cytologically confirmed stage IV non-small cell lung cancer, or recurrent non-small cell lung cancer which is not amenable to curative intent therapy. 2. Patients must have measurable disease by Response Evaluation in Solid Tumors(RECI... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Recurrent B-Cell Non-Hodgkin Lymphoma Recurrent Chronic Lymphocytic Leukemia Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Ly... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Men and women 18 years of age and older with histologically confirmed disease Active disease as defined by at least one of the following (IWCLL consensus criteria) Weight loss ≥10% within the previous 6 months Extreme fatigue Fev... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-49.0, West Nile Viral Infection Age >/=18 years and < 50 years 2.Able to read, sign, and date the informed consent document 3. Available and willing to participate for the planned duration of the study 4.Are in good health, as judged by the investigator and determined by vital signs, medica... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Diffuse Large B-cell Lymphoma The patient must, at the investigator's opinion, be able to meet all requirements of the clinical trial. 2. Patients must give voluntarily informed consent before performing any test test that is not part of routine care of patients. 3. Age between 18 and... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Recurrent Adult Acute Myeloid Leukemia Acute Myeloid Leukemia, in Relapse Male or female patients aged ≥ 18 years Documented definitive diagnosis of AML (according to WHO 2008) that is relapsed/refractory to standard treatment, for which no standard therapy is available or the patien... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-90.0, Osteoarthritis Age between 18 and 90 years Patients with no previous treatment Patients with Knee osteoarthritis grade 1-2 ( Kellgren-Lawrence based on radiographic findings) Age <18 and > 90 years Patients with Knee osteoarthritis grade 3-4 ( Kellgren-Lawrence based on radiographic ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, CLL New diagnosed patients with CLL (untreated) Not treated with immunoglobulin Not treated with steroids | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Richter's Transformation Histologically confirmed Richter's transformation (RT) from chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). 2. Availability of fresh or archived tumor tissue. 3. FDG PET-CT (disease) positive baseline scan with measurable disease. 4. ECOG p... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Mediastinal Lymphadenopathy adults (18 Years and older) with mediastinal lymphadenopathy known or suspected malignancy no informed consent pts with anterior mediastinal lesions contraindications to EBUS | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Crohn Disease Colitis, Ulcerative Intestinal Helminthiasis The included volunteer is a researcher within parasitology with main focus on Trichuris trichiura and Trichiura suis. He planned to infect himself and contacted our department with the purpose of being monitored during this in... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Rectal Adenocarcinoma Anal Adenocarcinoma Anal Squamous Cell Carcinoma Subjects with histologically confirmed stage II and III rectal adenocarcinoma or subjects with histologically confirmed stage II and III anal SCC 2. Subjects greater than 18 years of age. 3. Subjects who will unde... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Loss of Chromosome 17p Recurrent Chronic Lymphocytic Leukemia Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia Refractory Small Lymphocytic Lymphoma Richter Syndrome Patients will have a diagnosis of CLL or small lymphocytic lymphoma (SLL), refractory to o... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 9.0-17.0, Narrative Exposure Therapy Treatment as Usual 17 years old has spent some part of her/his life living in a country where organized violence was taking place, or at a refugee camp suffers from significant stress symptoms thought be trauma-related acute psychosis intellectual disability | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, B-cell Chronic Lymphocytic Leukemia Has Eastern Cooperative Oncology Group (ECOG) performance status of less than (<) 2 Has a diagnosis of Chronic Lymphocytic Leukemia (CLL) that meets published diagnostic (Hallek 2008): 1. Monoclonal B-cells (either kappa or lambda light chain restr... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphadenopathy Tuberculosis Sarcoidosis Patients with isolated intrathoracic lymphadenopathy Suspicion of primary lung cancer on CT or PET scan Suspicion of pulmonary tuberculosis on CT or PET scan Suspicion of sarcoidosis of lung parenchyma on CT or PET scan | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 1.0-80.0, Portal Vein, Cavernous Transformation Of Hypertension, Portal All patients with portal hypertention who have enough image information to confirm cavernous transformation of portal vein Patients with known severe dysfunction of heart, lung, brain, kidney and other vital organs | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Hypertension, Portal Portal Vein, Cavernous Transformation Of All patients with portal hypertension who have the history of splenectomy and have enough image information to confirm occlusion of portal vein Patients with known severe dysfunction of heart, lung, brain, kidney and other... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Men and women with histologically confirmed disease as defined by the following CLL: clonal B-lymphocytosis greater than or equal to 5,000 cells/microL SLL: lymphadenopathy with the tissue morphology of CLL but that are not leu... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lung Cancer Non-Small Cell Lung Cancer Ability and willingness to provide informed consent 2. Ability and willingness to comply with the requirements of the study protocol 3. Age >/= 18 years. 4. Representative tumor specimens in paraffin blocks (preferred) or at least 10 unstained s... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Anemia Cancer Fatigue Chronic Lymphocytic Leukemia Fever Infectious Disorder Lymphadenopathy Lymphocytosis Night Sweats Prolymphocytic Leukemia Recurrent Chronic Lymphocytic Leukemia Richter Syndrome Secondary Malignant Neoplasm Thrombocytopenia Weight Loss All patients must have a di... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Richter Syndrome Confirmed diagnosis of B-cell Chronic Lymphocytic Leukemia or Richter's Transformation Refractory to or relapsed after at least 1 prior treatment regimen Eastern Cooperative Oncology Group (ECOG) score of 0 to 2 Any major surgery, chemot... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 20.0-999.0, Chronic Lymphocytic Leukemia (CLL) Patients with confirmed diagnosis of CLL, either histologically proven or with immunophenotypical pattern by flowcytometry 2. The diagnosis of CLL was made after 2000; the complete medical history and the laboratory data are available for collection... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia NPP 1. Patients ≥18 years of age. 2. Eastern Cooperative Oncology Group (ECOG) performance status of ≤2. 3. A minimum of one prior line of systemic chemotherapy, chemo-immunotherapy, or an alemtuzumab-based regimen, consisting of at least two cycles of th... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-50.0, Beta-Thalassemia Sickle Cell Disease Provision of written informed consent for this study by subjects, or as applicable, subject's parent(s)/legal guardian(s) Treated with drug product for therapy of a hemoglobinopathy in a bluebird bio-sponsored clinical study Able to comply with stud... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-73.0, Lymphoma, B-Cell Lymphoma, Non-hodgkins Malignancy Patients with the following malignancies are potentially eligible: any B-cell lymphoma, and chronic lymphocytic leukemia (CLL). Patients with indolent malignancies that have transformed to diffuse large B-cell lymphoma are eligible Cl... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Multiple Myeloma Subjects must satisfy the following to be enrolled into the study: 1. Subject is ≥ 18 years of age at the time of signing the informed consent form (ICF) 2. Subject must understand and voluntarily sign an ICF prior to any study-related assessments/procedures being co... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Mediastinal Lymphadenopathy Non-small Cell Lung Carcinoma Sarcoidosis ≥18 years of age Suspected or tissue proven sarcoidosis (stage I or II based on CT/PET-CT) and referred for diagnostic endosonographic work up or Suspected or tissue proven NSCLC with suspected mediastinal lymph no... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cold Agglutinin Disease Autoimmune Hemolytic Anemia CAD diagnosis defined by the combination of - 1. Chronic hemolysis 2. Cold agglutinin titer 64 or higher 3. Positive direct antiglobulin test when performed with polyspecific antiserum, negative (or only weakly positive) with anti-I... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Mediastinum Age 18 years and Older Predominant Subcarinal or Lower Left paratracheal located mediastinal lymphadenopathy/mediastinal lesions at least >1cm in Short axis diameter Patients who give consent Refusal of consent for the procedure Any contraindications to Bronchoscopy / En... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cancer of the Lung Lung Cancer Lung Neoplasms Adenocarcinoma of the Lung Non Small Cell Carcinoma of the Lung Small Cell Carcinoma of the Lung years of age or older, not previously diagnosed with cancer (except for basal cell carcinomas of the skin or a diagnosis of cancer within a m... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Arthroscopic Knee Surgery Lower Limb Fractures Back Pain and Asymmetric Gait Complex Regional Pain Syndrome days to 1 month following arthroscopic knee surgery(n=10) Following fractures in lower limb with pain during weight-bearing (n=10) Back pain and asymmetrical gait (n=10) Comple... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-90.0, Leukemia, Lymphocytic, Chronic, B-Cell patients fulfilling clinical and immune-phenotypic for CLL none | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-90.0, Leukemia, Lymphocytic, Chronic, B-Cell patients with CLL | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-99.0, Leukemia, Lymphocytic, Chronic, B-Cell Diagnosis of Chronic Lymphocytic Leukemia (CLL) established according to International Workshop Chronic Lymphocytic Leukemia (IWCLL) criteria Relapsed or refractory CLL pre-treated with at least one prior line of systemic therapy for CLL Indicati... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Prostate Cancer men in the Västra Götaland healthcare region diagnosed with prostate cancer of intermediate risk-level (T1-T2, Gleason score <8 and PSA<20) scheduled for radical prostatectomy ongoing hormonal treatment other difficult physical or psychological conditions diminished c... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Hepatic Cirrhosis At the risk of gastroesophageal variceal hemorrhage; Acute gastroesophageal variceal hemorrhage;Haematemesis and/or melena result in gastroesophageal variceal haemorrhage of liver cirrhosis in the past Splenomegaly or hypersplenism acting as thrombocytopenia (PLT < 7... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, CLL CLL patients intended to receive treatment in 30 days from recruitment to the study CLL patient not about to receive treatment in 30 day of recruitment to the study | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Non-Small-Cell Lung Cancer ≥19 years of age 2. Patients with a primary diagnosis of NSCLC within the past 5 years who are eligible for their first systemic therapy based on disease characteristics. Systemic therapy may any cytotoxic, targeted, immune-based, or otherwise non-local trea... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, CLL SLL HCL Richter´s Transformation Leukemia, Prolymphocytic, B-Cell Leukemia, Prolymphocytic, T-Cell T-LGL Leukemia NK-LGL Leukemia (all must apply) 1. Confirmed diagnosis of CLL, B-PLL, T-PLL, SLL, T or NK-LGL, HCL or Richter's transformation 2. 18 years of age or older 3. Signed,... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cancer Patient with a histologically proven cancer regardless of the location (solid tumor or not) except brain tumor 2. Patient should receive chemotherapy (any indication) associated with overall risk of neutropenia greater than or equal to 20% 3. Age ≥ 18 years 4. Performance Stat... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-95.0, Leukemia, Lymphocytic, Chronic, B-Cell Diagnosis of chronic lymphatic leukemia Score of Matutes <4 | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 1.0-31.0, B Acute Lymphoblastic Leukemia Central Nervous System Leukemia Ph-Like Acute Lymphoblastic Leukemia Testicular Leukemia Patients must be enrolled on APEC14B1 and consented to Screening on the Part A consent form prior to enrollment on AALL1131 White Blood Cell Count (WBC) Age 1-9.99 ye... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Haemodialysis >18 patient under haemodialysis treatment patient not objecting to study Patient with known cardiac arrythmias | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 19.0-999.0, Leukemia, Lymphocytic, Chronic, B-Cell Diagnosis of CLL meeting published diagnostic criteria. 2. CLL currently being treated with Ibrutinib due to relapsed/refractory disease or primary del17p cytogenetic lesions at a daily dose of 420 mg and failure of plasma b2M levels to decrease... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Gastric Adenocarcinoma Esophageal Squamous Cell Carcinoma Nasopharyngeal Carcinoma Head and Neck Squamous Cell Carcinoma "Inclusion Subjects may be entered in the study only if they meet all of the following 1. Fully understand the study and signed the Informed Consent Form (ICF) volu... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, B-cell Non-Hodgkins Lymphoma Chronic Lymphocytic Leukemia Able to provide written informed consent Diagnosis of either Non-CLL B cell malignancy or CLL/SLL Ineligible for or have exhausted standard therapeutic options and have relapsed or refractory disease ECOG performance status 0-... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Endobronchial Transbronchial Needle Aspiration Lung Cancer Procore mediastinal lymphadenopathy >10 millimeters lung cancer suspected coagulopathy contraindication for midazolam contraindication for bronchoscopy | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Anemia Fatigue Fever Lymphadenopathy Lymphocytosis Night Sweats Recurrent Chronic Lymphocytic Leukemia Recurrent Plasma Cell Myeloma Refractory Chronic Lymphocytic Leukemia Refractory Plasma Cell Myeloma Splenomegaly Thrombocytopenia Weight Loss All subjects must have the ability to ... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphadenopathy Indication for EBUS-TBNA Patient has provided written informed consent | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Documented CLL requiring treatment according to iwCLL 2. Age at least 18 years 3. Life expectancy ≥ 6 months 4. Ability and willingness to provide written informed consent and to adhere to the study visit schedule and other protocol requirements 5. Adequa... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia (CLL) Small Lymphocytic Lymphoma (SLL) Participant must have a diagnosis of relapsed or refractory chronic lymphocytic leukemia (CLL)/SLL that meets 2008 Modified International Workshop for Chronic Lymphocytic Leukemia (iwCLL) NCI-WG Guidelines and the fo... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-99.0, Chronic Lymphocytic Leukemia (CLL) Eastern Cooperative Oncology Group (ECOG) performance score of less than or equal to 2 Participant has relapsed/refractory disease (received at least one prior therapy) Diagnosis of CLL that meets published 2008 Modified International Workshop on CLL... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Anemia B-Cell Prolymphocytic Leukemia Grade 1 Follicular Lymphoma Grade 2 Follicular Lymphoma Grade 3a Follicular Lymphoma Hairy Cell Leukemia Lymphoplasmacytic Lymphoma Mantle Cell Lymphoma Marginal Zone Lymphoma Recurrent Chronic Lymphocytic Leukemia Recurrent Small Lymphocytic Lym... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-60.0, Lymphoma, Large B-Cell, Diffuse NCCN-IPI>1 Known IPI, cell of origin and DHL at time of diagnosis Negative pregnancy test Men must agree not to father a child during the therapy to 8 cycles R-CHOP/like, total of 8 x Rituximab CR, CRu Transformed lymphoma Secondary malignancy HIV posi... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 3.0-70.0, Acute Lymphoblastic Leukemia Immune System Diseases Immunoproliferative Disorders Cell Procurement Written informed consent for procurement signed by subject/legal guardian of pediatric subject and HIPAA authorization Age 3-17 years of age for pediatric subjects (weight must be ≥10 kg)... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Cholangiocarcinoma only those positive for CA19.9 pregnant and lactating females | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 50.0-90.0, Osteoarthritis Pain Syndrome Intra-articular Injection According to radiographic findings, patients who are suffering from knee OA for over 3 months have to be stage II-IV according to the Kellgren-Lawrence (KL) grade by a senior radiologist. The diagnosis of symptomatic knee OA is ba... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Hemophilia B for patients Were screened and consented for the AskBio009-101study at any point in time Are able to speak and understand English Are between ages of 18 and 75 Are physically able to participate in a one-hour phone interview Consented into this study independently of the ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Richter Syndrome Must have a confirmed diagnosis of chronic lymphocytic leukemia or small lymphocytic lymphoma as per IW-CLL 2008 (Hallek et al, 2008) with biopsy proven transformation to diffuse large B cell lymphoma (DLBCL), consistent with Richter's Syndrome Age greater than or eq... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Have received at least one dose of Obinutuzumab as per local label and clinical practice Included in clinical trial | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Chronic Hepatitis C (Disorder) Positive serum Anti-HCV antibody or serum HCV-RNA, CHC patients without any treatment Patient has a history of clinical signs/symptoms of hepatic decompensation (Child-Pugh Grade B or C) or ascites, esophageal variceal bleeding, hepatic encephalopathy, ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Crohn Disease Ulcerative Colitis Intestinal Helminthiasis The included volunteer is a researcher within parasitology with main focus on Trichuris trichiura and Trichiura suis. He planned to infect himself and contacted our department with the purpose of being monitored during this inf... | 0 |
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