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41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 12.0-999.0, Seizure Disorder Generalized Tonic Clonic Clinical diagnosis of PGTC seizures (with or without other subtypes of primary generalized seizures) and experiencing greater than or equal to 3 PGTC seizures during the 8-week period prior to randomization 2. Have had a routine electroenceph...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsy Target disease: Subjects with newly diagnosed epilepsy or recurrent epilepsy which is untreated, having the following seizure types as classified by the International Classification of Seizures Partial seizures (with or without secondarily generalisation) Generalized tonic-c...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-40.0, Idiopathic Generalized Epilepsy For patients Men and women aged between 18 and 40 Person affiliated to social security or beneficiary of such a regime idiopathic generalized epilepsy treated with lamotrigine, an association of lamotrigine, topiramate, levetiracetam, lamotrigine or lev...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 12.0-45.0, Acne Vulgaris Male or female subjects 12 to 45 years (inclusive) of age in good general health Subjects must have both on the face: A) A minimum of 17 but not more than 60 inflammatory lesions (papules/pustules), including nasal lesions. And B) A minimum of 20 but not more than 150 no...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Acute Myelogenous Leukemia (AML) For Arm A Part 1 (monotherapy/dose escalation): refractory or recurrent AML, not an appropriate candidate for standard therapy For Arm A Part 2 (monotherapy/dose confirmation/cohort expansion): refractory or recurrent AML, not an appropriate candidate...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Anxiety Disorder Seizures Epilepsy Partial Epilepsy Depression Patients may be male or female Patients will be aged 18 65 Patients must have at least 3 seizures during the one-month baseline Localization-related epilepsy diagnosed by standard clinical that has not responded to treatme...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Intraventricular Hemorrhage Intracerebral Hemorrhage Hospitalization for an admitting diagnosis of hemorrhagic stroke admitted to the neurosurgical intensive care unit Age greater than 18 years No evidence of ischemic cerebrovascular injury Concomitant traumatic brain injury Antibio...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Refractory Epilepsy Fulfilling the of labeling indications of Medtronic® DBS™ Therapy for Epilepsy Patient with diagnosis of refractory epilepsy as defined by 1981 ILAE (International League Against Epilepsy) classification, who have been implanted or will be implanted with Medtronic...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Stress Anxiety Depression Documented HIV-1 infection Ages 18 to 65 Experiencing some level of stress, anxiety, or depression No current use of other meditation practices or holistic modalities Non-English readers or speakers Hearing-impaired Low literacy below 5th grade reading and c...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-40.0, Medically Intractable Epilepsy Age 18-40 years old Fluency in English, including reading and writing Confirmed diagnosis of epilepsy as indicated by review of medical records (video-EEG, routine EEG and imaging) Drug-refractoriness as indicated by at least two failures to achieve seiz...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-50.0, Epilepsy, Cryptogenic Epilepsy, Partial Seizure Disorder Autoimmune Diseases, Nervous System Limbic Encephalitis Diagnosis of uncontrolled epilepsy with at least two seizures a month for three consecutive months Age 18 to 50 Clinical semiology or electroencephalogram (EEG) consistent ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-75.0, Epilepsy Patient with temporal lobe epilepsy (TLE) Patient with epilepsy for at least two years. Arm 1: Patient with drug-resistant TLE proved potentially a candidate for surgery. Arm 2: Patient with TLE seizure-free for 12 months or more Patient with a scalable general pathology may...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Diagnosed with Epilepsy Age (under 18, over 65)
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-55.0, Major Depressive Disorder For Patients with Major Depressive Disorder • Male and female outpatients, aged 18-55 years Subjects meeting full for the diagnosis of current Major Depressive Disorder (MDD) without psychotic features, as determined by clinical evaluation and Mood Module of ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Osteoarthritis of the Knee Willing and able to give written informed consent Willing and able to understand the study procedures, and comply with all study procedures Females or males, age ≥ 18 years old Body mass index 18-39, inclusive In good general health Clinical diagnosis of OA...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 10.0-999.0, Minor Head Injury Patient with acute MHI was defined as a patient having a blunt trauma to the head within 24 hours with a Glasgow Coma Scale (GCS) of 13 to 15 and at least 1 of the following risk factors: history of loss of consciousness, short-term memory deficit, amnesia for the t...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Intellectual Disabilities Intellectual disability Visual impairments Auditory impairments Currently receiving cognitive behaviour therapy Acute psychosis
2
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-999.0, SUDEP Sudep Group Subjects diagnosed with epilepsy whose cause of death was sudden and unexplained, and whose families are willing to participate, will be included in the study. Control Group For the control group, we will any patient diagnosed with epilepsy currently in the care of t...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Epilepsies, Partial For patients Age 18-60 Able to give written informed consent Drug resistant participants will be defined as having clinically documented partial seizures with consistent EEG evidence as defined by the 2010 Revised terminology and concepts for organization of seizur...
2
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Focal Epilepsy With and Without Secondary Generalization The patient has not received Vimpat® more than 7 days prior to start of Non-Interventional Study (NIS) The patient must have a diagnosis of epilepsy with partial-onset seizures with or without secondary generalization Based on ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-75.0, Hemifacial Spasm patients referred to the neurosurgical service for microvascular decompression surgery for HFS males and females 18 to 75 years of age otherwise normal neurological exam signed informed consent Botox treatment within the last three months
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Partial Epilepsy Patient with drug-resistant focal epilepsy Candidates for pre-surgical evaluation including FDG PET, MRI, MEG and SEEG recordings Age 18-65 years EEG-confirmed focal epilepsy for >2 years Signed informed consent form Age <18 years and >65 years Contraindication to th...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-75.0, Epilepsies, Partial fully characterized refractory unifocal neocortical epilepsy (i.e. the epileptogenic zone is well defined) on a stable drug regimen for at least one month able to complete a seizure dairy either by the patient or by a significant other Metal in the head including ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 5.0-18.0, Migraine Children with migraine without aura (MoA) diagnosed according to the for pediatric age of the International Classification of Headache Disorders (IHS-2) aged from 5 to 18 years at least four attacks /month mental retardation (IQ <70) genetic syndromes (e.g., Down syndrome, Pr...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Seizure Disorder US Veteran Epilepsy (Seizure Disorder) >18 years
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy (Treatment Refractory) Male or female, aged 18 years or older Female subjects must be using a form of contraception >1 seizures per month EEG confirmation of seizure activity (no non-epileptic seizures) Agrees to comply with study procedures, and keep seizure diary Agrees not...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy years of age or older Diagnosed with epilepsy and expected to have at least one motor seizure in the EMU Determined by the Investigator to be an acceptable candidate for epilepsy evaluation with intracranial or scalp electrode monitoring Willing and able to wear 3 ActiGraph ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-70.0, Seizures Sleep Epilepsy epilepsy non-epileptic
2
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-999.0, Intellectual Disability for the patients: Clinical diagnosis of intellectual disbility for the unaffected sibs: to be aged at least 3 years informed consent absence of informed consent
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Phantom Limb Pain Men and women 18 years or older Amputation at any level of one lower limb by anti-personnel land mines Symptoms compatible with PLP, defined as painful sensation, sensation of shooting, stabbing, boring, boring, sqeezing, throbbing and burning or paresthesia or any ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 5.0-16.0, Epilepsy, Partial Epilepsy, Localization Related Age of participant between 5 years, 6 months and 16 years, 0 months at the time of enrollment Weight is between ≥ 15 kg the lower limit BMI 99th percentile at study entry at study entry Child has diagnosed epilepsy as defined by one of t...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Seizure The patient is diagnosed with epilepsy with; primary generalized tonic-clonic or partial complex or simple complex or focal onset seizures, with or without secondary generalization. 2. The patient's present antiepileptic drug (AED) therapy is ineffective or intolerable 3. The ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Intellectual Disability Participants were can write and read to ask scales Participant were able to use an Smartphone Physical illness that prevent physical activity
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsy Partial Seizures Subject is of Chinese origin and ≥ 16 years of age Subject is newly or recently diagnosed with Epilepsy, having experienced unprovoked Partial-Onset Seizures (POS) Subject has experienced at least 2 unprovoked seizures in the year preceding randomization, of...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Seizure Disorder Age 18-65 Partial onset seizures (complex partial or secondary generalized tonic-clonic) At least one seizure every three months No serious or progressive medical or psychiatric illness At least one complex partial or generalized tonic-clonic seizure in the last three...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 4.0-999.0, Lennox-Gastaut Syndrome Patients will be four years and older Patients will have an established diagnosis of Lennox-Gastaut syndrome, and Documented history or current presence of multiple seizure types associated with LGS (including tonic or atonic seizures (drop attacks) and atypica...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 40.0-65.0, Adult Lymphoblastic Lymphoma Disease ALL in complete remission (CR) at the time of transplant. Remission is defined as "less than 5.0% bone marrow lymphoblasts by morphology," as determined by a bone marrow aspirate obtained within 2 weeks of study registration Philadelphia chromosome...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Breast Cancer Nos Metastatic Recurrent Women Aged 18 years and over With an invasive breast cancer diagnosed by cytology or histology Tumors cT0 to cT3, CN0-3 No clinical evidence of metastasis at the time of Untreated including scored for breast cancer surgery in progress Patient re...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Thyroid Cancer Newly diagnosed with a first occurrence of thyroid cancer <2-4 weeks of diagnosis (i.e., histologically confirmed thyroid cancer (papillary, follicular, or medullary type; TNM classification system) Willing to participate in the EG meetings >18 years Alert and capable ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Chronic Pain Women Clinical diagnosis of chronic pelvic pain More than eighteen years Non-menstrual or noncyclic pelvic pain Duration of pain of at least 6 months Duration of pain less than 6 months Women who were pregnant in the last 12 months
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Coronary Artery Stenosis Age ≥ 18 years Patient with an indication for PCI including angina (stable or unstable), silent ischemia (in absence of symptoms a visually estimated target lesion diameter stenosis of ≥70%, a positive non-invasive stress test, or FFR ≤0.80 must be present), ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 13.0-70.0, Acute Injury of Anterior Cruciate Ligament Skeletally mature subjects with age 13 years Sustain an acute full ACL rupture in one knee < 28 day May or may not undergo ACL reconstruction Low grade injury to the collateral ligaments not resulting in instability and not requiring reconstr...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 40.0-80.0, Amnesia Patient group Clinical of definition of transient global amnesia: Acute disorder of anterograde memory observed by a witness. Respect of the other cognitive functions. No for this diagnosis (see section). Hippocampal lesion in DWI MRI performed at 72h Clinical resolution of m...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-999.0, Respiratory Complication Morbid Obesity All patients scheduled for bariatric surgery at Flagler Hospital will be included after written and informed consent Patients will be excluded from the study if they don't consent to participate in the study. Patients allergic to any of the stu...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Peritoneal Carcinomatosis Colorectal Cancer Appendiceal Cancer Peritoneal Mesothelioma Pseudomyxoma Peritonei Gastric Cancer Age ≥ 18 years Capable of providing informed consent The patient who has not previously received hyperthermic intraperitoneal chemotherapy must have histopatho...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 12.0-999.0, Severe Hemophilia A Key Have severe hemophilia A Previously treated subject, defined as having at least 150 documented prior exposure days to any recombinant and/or plasma-derived FVIII and/or cryoprecipitate products (other than any use of rFVIIIFc study drug or commercial product) ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 12.0-60.0, Epilepsy Presurgical candidates with pharmacoresistant partial seizures despite optimal medical treatment and history of medically refractory medial temporal lobe epilepsy Age above 12 years, below 60 years Average of 2 partial seizures per month during a baseline of 2 months Recordin...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-0.333, TSC Tuberous Sclerosis Complex Epilepsy for TSC patients male or female infants with a definite diagnosis of TSC (Roach criteria; Roach 1998 or DNA confirmed) age up to 4 months at the moment of enrolment no clinical seizures seen by caregivers or on baseline videoEEG recording writte...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-999.0, Intellectual Disability uses AAC with client client has congenital intellectual disability supports client for at least 6 months client has dementia symptoms client has severe, non-corrected visual impairment client has diagnosed autism
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy aged 18-65 years Patients with epilepsy who take by topamax 100mg bid or who need to take topamax 100mg bid poor compliance subjects whose dose of antiepileptic drug are changed during the study subjects whose seizure is not well-controlled judged by neurologist history of a...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-45.0, Healthy Volunteer between 18 and 45 years old 2. right-handed. 3. Fluent in English. 4. able to provide written informed consent. 1. Has a dermatological condition such as scars, burns, callouses, or tattoos that might influence cutaneous sensibility on the hands 2. Has had recent or ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 12.0-60.0, Focal Epilepsy Clinical seizure(s) and history consistent with focal epilepsy At least two confirmed spontaneous seizures, at least 24 hours apart, in the 12 months prior to enrollment Complete AED history prior to enrollment (with approximate dates and doses) is available (exception ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Cervical Dystonia • 18-65 year old male and female patients with primary cervical dystonia Subject may be untreated with botulinum toxin; treated with botulinum toxin but who are at least 8 weeks (+ 1 week) from a previous injection; or who have experienced an insufficient response to...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Patients are diagnosed with medically intractable epilepsy patients have frequent interictal spikes on clinical EEG monitorings patients without large morphological abnormalities Patients with skull bony defects, intracerebral mass lesions, major brain malformations, large c...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-999.0, Severe Intellectual Disability Patients with severe intellectual disability (IQ <35 ) or moderate (IQ <50) isolated or syndromic presentation but undiagnosed . The diagnosis is established during genetic counseling of a 6 CHU interregion Lack of family history ( parents). We are inter...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.333-0.833, Gross Motor Development Delay Cerebral Palsy will be based on delayed psychomotor development, as assessed by Alberta Motor Infants Scale, using -2SD as a cut-off point. Neurological signs will be investigated by Hammersmith Infant Neurological examination (HINE) together with a cli...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Male and female patients aged 18-65 years Patients with simple or complex partial seizures with or without secondary generalization since at least one year prior to randomisation visit At least 4 seizures per month within the last 2 months prior to randomisation Stable dose r...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 9.0-999.0, Acne Vulgaris The Subject has a facial acne severity grade of IGA grade 3 (moderate) at Screening and Baseline visits The Subject has a minimum of 20 inflammatory lesions and 25 non-inflammatory lesions at Screening and Baseline visits on the face The subject has severe forms of acne...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-55.0, Cognition Disorder Attention Deficit Disorder Traumatic Brain Injury To be included in the protocol, study participants must meet the following 1. Age 18 years, inclusive 2. A history of having sustained a moderate or severe TBI >= 6 months prior to enrollment. Evidence will be any on...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 3.0-15.0, Cortical Dysplasia Children aged 3 years; 2. MRI changes consistent with a diagnosis of FCD type II a or b; 3. History of at least two epileptic seizures in the past 6 months before randomisation; 4. Seizure semiology consistent with focal onset, agreed after pre-surgical discussion to...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Epilepsy age between 18-70 years 2. diagnosis of temporal lobe epilepsy, with seizure focus defined by seizure semiology, EEG, MRI Brain, PET and/or ictal and interictal SPECT. 3. Must have a stable seizure frequency in the two (2) months prior to enrollment, as verified by the patien...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Brain Tumor Related Epilepsy (BTRE) Patient has never been treated with lacosamide (LCM) prior to this non-interventional study (NIS) or treatment with LCM for the first time started no earlier than 7 days prior to enrollment in this NIS The decision by the treating physician to pres...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.167-2.0, Infantile Spasms Age 2-24 months 2. Clinical spasms 3. Initial EEG with hypsarrhythmia or modified hypsarrhythmia The do not quantify the initial severity or frequency of infantile spasms. Infantile spasms is a unique epileptic disorder characterized by clusters of brief infantile spa...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Psychogenic Non Epileptic Seizure Patient above 18 years old Affiliation to social security Evolution disorders for over three months with at least 3 psychogenic non-epileptic seizures spaced over 24 hours and less than two years Diagnosis of PNES (associated or not with epilepsy) or...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy For Adult patient (≥ 18 years) suffering from drug-resistant partial epilepsy Patient undergoing long-term video-EEG monitoring in one of the participating centre to record and characterize its seizure Patient who gave its written informed consent to participate to the study...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-64.0, Epilepsy, Temporal Lobe Diagnosis of mesial temporal lobe epilepsy based on the combination of clinical semiology, neuroimaging findings, and electroencephalogram results At least 1 seizure with loss of awareness per 4-week period, on average, despite the use of antiepileptic drugs P...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Focal Seizures For in Part B of the study patients must fulfil ALL of the following Male or female aged between 18 and 65 years, inclusive Well-documented history of focal epilepsy, compatible electroencephalogram and clinical history Documented computerized tomography / magn...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Focal Seizures For in Part A of the study patients must fulfil ALL of the following Male or female aged between 18 and 65 years, inclusive Well-documented history of focal epilepsy, with focal seizures as the primary seizure type, compatible electroencephalogram and clinical ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 2.0-99.0, Epilepsy Generalized Tonic-Clonic Seizures Subject has a history of GTC seizures, either primary GTC or partial onset seizures with secondary generalization. 2. Is being admitted to a hospital for routine vEEG monitoring related to seizures. 3. Male or female between the ages of 2-99. ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy A clinical decision to treat the patient with the RNS System in accordance with its approved indication for use has been made prior to enrollment in the study. For approved indication for use and contraindications, refer to current physician labeling and instructions for use...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 4.0-999.0, Epilepsy Subject with a confirmed diagnosis at least 24 weeks prior to Visit 1 and a disease onset prior to 30 years of age, consistent with idiopathic generalized epilepsy (IGE) experiencing primary generalized tonic-clonic (PGTC) seizures (Type IIE) that are classifiable according t...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 6.0-80.0, Epilepsy Epilepsy patients with prominent interictal epileptiform discharges (IEDs) on EEG Epilepsy patients with no prominent interictal epileptiform discharges (IEDs) on EEG
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsy adults with no contraindications to MRI scanning. Initial screening for MR compatibility will be performed at recruitment. 2. epilepsy with interictal epileptic discharges evident on scalp EEG. 3. rarity or lack of seizures. This is an important point to minimise the risk of...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-59.0, Epilepsy Seizures, Epileptic The patient has been correctly informed The patient must have given his informed and signed consent The patient must be insured or beneficiary of a health insurance plan The patient is at least (≥) 18 years old and less than (<) 60 years old The patient ha...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 20.0-80.0, Bladder Cancer all patients anticipating transurethral resection of bladder tumors with American Society of Anesthesiologists physical status(ASA) I or II patients with diabetes or peripheral neuropathy; motor or sensory deficits in the lower extremities, ASA greater than III, coagul...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 15.0-999.0, Epilepsy Age greater than or equal to 15 years Patients with drug-partial resistant epilepsy with the following characteristics Disabling epilepsy despite an optimized pharmacological treatment An average of one seizure a day or more during the week preceding the Focal epilepsy in wh...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Hemispatial Neglect Written informed consent Healthy participants Age 18-80 years Neurologically healthy, i.e., with no documented or present neurological disease or brain injury normal or corrected-to-normal visual acuity Patients Age 18-80 years Showing signs of left hemispatial neg...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Heart Rate Nocturnal Seizures Autonomic Nervous System Epilepsy Clinically firm diagnosis of epilepsy. 2. 18 years of age 3. Having the capacity to consent to this project Patients who are on medication for cardiac conditions like beta blockers, anti arrhythmic agents, calcium channe...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.083-3.917, Epilepsy With Partial-onset Seizures Subject is male or female from >=1 month (ie, 4 weeks after full term [37 weeks gestational age]) to <4 years of age Subject has a diagnosis of epilepsy with partial-onset seizures. The results of >=1 prior EEG and >=1 magnetic resonance imaging/...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 10.0-18.0, Intellectual Disability Intellectual disabilities (ID) group children with mild to moderate intellectual disabilities able to walk independently can follow simple commands 2. Typical developed children age-matched TD children fracture or receive orthopedic surgery within six months. ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Highly Drug-resistant Focal Epilepsy Subject is an adult (18 years of age or more) Subject is able to understand the study and the ICF as assessed by the Investigator. Subjects with known mental retardation (defined as IQ below 70) are not eligible to participate. Subject and/or care...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Epilepsy Clinical diagnosis of symptomatic epilepsy Disease progression for the last 1-3 years Resistance of epilepsy to therapy with carbamazepine, valproic acid, topiramate, lamotrigine, and phenobarbital (anti-epileptic drugs/AEDs) as monotherapies or combination therapies Signed i...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-90.0, Cortical Spreading Depolarization Cortical Spreading Depression Subarachoid Hemorrhage Traumatic Brain Injury GCS <8 SAH or severe traumatic brain injury requiring craniotomy Consent obtainable (via legal representative) Ictus (bleed or injury) within 48 hours of enrollment Clinically...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Epilepsy Refractory unifocal epilepsy Early ictal SPECT with intravenous injection did not localize the ictal onset zone Several seizure per day, or clusters of several seizures per day Seizures are of short duration (i.e. less than 10-15 seconds) Patient asks for epilepsy surgery Re...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, COPD The established were: having a COPD (COPD was confirmed if the post-bronchodilator forced expiratory volume in one second (FEV1) divided by the forced vital capacity was less than 0.7 (FEV1/FVC<70%) and having been admitted at least twice in the previous year or three times in t...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Partial Epilepsy Male or female and greater than or equal to 18 years of age at the time of signing the informed consent. The upper age limit is 70 years inclusive. 2. Weight at least 30 kg 3. Written informed consent signed by the subject or legal guardian prior to entering the study...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.083-21.0, Train-of-Four-Monitoring general anesthesia participation in another trial refusal of participation state after burns diabetes mellitus reflux disease difficult airway pregnancy Medications volatile anesthetics antibiotics (Aminoglykoside, Polymyxin, Clindamycin, Lincomycin, Tetrazy...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Key Participant must have had epilepsy, as determined by the investigator, and must have been taking CLB Participant must have had a documented magnetic resonance imaging/computerized tomography of the brain ruling out a progressive neurologic condition Participant must have ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Ictal/Post-ictal Hypoxemia Patient suffering from drug-resistant focal epilepsy Age ≥ 18 years Patient for whom a video-EEG monitoring of their seizures was scheduled as part of a pre-surgical assessment For women of childbearing age, a method of contraception considered eff...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Patients over 18 years patients definitively diagnosed Focal Epilepsy based on clinical and additional tests patients with stable and identifiable antiepileptic treatment during the last two years patients according to the investigator are able to provide clinical data neces...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Severe Sepsis Prior written informed consent of the patient. If this is not possible, it will be necessary for the investigator to obtain initial informed consent according to the requirements. The legally authorized representative has to provide the written informed consent or in his...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Epilepsy patients with planned intracerebral exploration (SEEG) informed patient patient affiliated to French social security Patients under 18 Pregnant or breastfeeding women Patients deprived of liberty by legal decision Patients not covered by social security Patients wh...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, IgG4-related Sclerosing Cholangitis IgG4-related Disease The presence of a biliary stricture years and older Consented to IRB 707-03 Younger than 18 years of age Unable to collect a bile sample Abnormal postsurgical anatomy preventing collection of a bile sample
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Highly Drug-resistant Focal Epilepsy A written Informed Consent form approved by the Independent Ethics Committee is signed and dated by the subject, after the Investigator assesses whether the subject is able to understand the potential risks and benefits of participating in the stu...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 8.0-999.0, Epilepsy Cancer Brain Neoplasm To be eligible for entry into the study, a candidate must meet all the following Be 8 years of age or older Have solitary primary or recurrent brain tumor with associated seizures. Brain tumor may be diagnosed radiologically. Associated seizures are defi...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Traumatic Brain Injury (TBI) 60 years of age Fluent in English Documented history of TBI or blast exposure since 2001 Inability to have MRI Pregnancy History of TIA within last 6 months Presently involved in open litigation
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41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 1.0-60.0, Epilepsy Ages 1-60 years of age. 2. Patient must have at least 4 clinically countable seizures per month. They must also have prior concomitant video-EEG with evidence documenting a diagnosis of epilepsy. Seizure history to a documented history of generalized seizures (drop attacks, at...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsy With POS With or Without Secondary Generalization Patient has never been treated with brivaracetam (BRV) prior to enrollment in this Non-Interventional Study (NIS) The decision by the treating physician to prescribe BRV is made independently of the participation in the NIS P...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 2.0-999.0, Rett Syndrome Diagnosis of Classic Rett syndrome as defined by the clinical consensus Presence of a MECP2 mutation Post-regression stage of development, defined as greater than 6 months since the last loss of hand use or verbal language Average of at least 4 observable seizures (gener...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-45.0, Seizures, Focal All patients with the clinical diagnosis of localization related epilepsy/focal seizure (International League Against Epilepsy 2010) with a history of an episode of seizure within 48 hours of presentation Treatment naïve patients or patients who had not taken any treat...
1