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41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Epilepsies, Partial Seizures History of simple or complex partial epilepsy that has been documented or witnessed during a 12-week baseline phase, patient must have at least 12 partial seizures while maintaining therapeutic levels of antiepileptic drugs (AEDs) and have no more...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Epilepsies, Partial Seizures History of simple or complex partial epilepsy that has been documented or witnessed an electroencephalogram (EEG) during the preceding 5 years that has a pattern consistent with the diagnosis of partial epilepsy during an 8-week baseline phase, pa...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Epilepsies, Partial Seizures History of simple or complex partial epilepsy that has been documented or witnessed an electroencephalogram (EEG) during the preceding 5 years that has a pattern consistent with the diagnosis of partial epilepsy during an 8-week baseline phase, pa...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Epilepsies, Partial Seizures History of simple or complex partial epilepsy that has been documented or witnessed an electroencephalogram (EEG) during the preceding 5 years that has a pattern consistent with the diagnosis of partial epilepsy during an 8-week baseline phase, pa...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Neurodegenerative Diseases Mild Cognitive Impairment years or older Healthy person without memory complaints OR person diagnosed with a neurodegenerative disease (ie, Alzheimer's disease, Parkinson's disease, multiple sclerosis) MR contraindication such as metal in body (ie, pacemak...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Heart Failure, Congestive New York Heart Association (NYHA) Class II Left ventricular ejection fraction (LVEF) less than or equal to 30% by multigated acquisition scan (MUGA)/catheterization OR LVEF less than or equal to 30% and LV end diastolic dimension ≥ 60 mm (by echocardiogram) ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Epilepsy for enrollment: 1. Subject has disabling motor simple partial seizures, complex partial seizures, and/or secondarily generalized seizures. Disabling refers to seizures that are severe enough to cause injuries or significantly impair functional ability. 2. Subject's seizures a...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 10.0-999.0, Epilepsy Seizures Epilepsies, Partial Epilepsy, Generalized Seizures, Tonic-Clonic Patients having new-onset epilepsy or epilepsy relapse characterized by partial-onset seizures or primary generalized tonic-clonic seizures having at least 1 seizure within the 3 months prior to entry ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 13.0-85.0, Epilepsy Patients with a recent diagnosis epilepsy Able to describe their symptoms by themselves Have had at least 2 episodes of seizures during the previous year Have had at least 1 headache during the previous year Well-controlled epileptic patients taking anti-epileptic medication...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Heart Failure age greater than 18 years old, 2. CHF diagnosis for more than 6 months regardless of etiology, 3. echocardiography-based left ventricular ejection fraction equal or less than 40%, and 4. prior CHF admission within three months from randomization thoracic deformity or s...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 3.0-999.0, Epilepsy typical history of focal seizures EEG centrotemporal sharp waves age of onset 3-12 years no previous epilepsy type (febrile seizures OK) normal development normal neurological examination normal MRI/CT (if done) only history of secondary generalized seizures atypical history/...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 2.0-999.0, Seizures Epilepsy Non-premenopausal female patients using a medically acceptable contraceptive method as discussed with their doctor History of the type of seizure during the period prior to in the study and sufficient medical records to document this. Prior treatment until in the stu...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Schizophrenia Heavy Smoking Age 18-65 male or female. 2. DSM -IV for chronic schizophrenia or schizoaffective disorder. 3. Ability and willingness to sign informed consent for participation in the study. 4. Patients' expressed interest in participating in a smoking-reduction program 5...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Epileptic adult patients treated at a stable dose with one or more AEDs for ≥ 3 months Symptomatic epilepsy due to malignant brain tumour or progressive brain disease Confirmed diagnosis of a concomitant chronic disease
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 40.0-999.0, Osteoarthritis clinical evidence of osteoarthritis of the hip, knee, or spine joint for ≥ 1 year currently adequately treated with short acting opioids taking ≥ 30 and ≤ 80 mg oral morphine or morphine equivalents per day for ≥ 2 weeks for control of their osteoarthritis pain requir...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 6.0-65.0, Severe Hemophilia A Male At least 6 years of age and not more than 65 years of age Signed and dated Informed Consent Form and Patient Authorization for Release of Information approved by the appropriate Institutional Review Board (IRB) prior to screening and enrollment. If the subject ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Severe Sepsis Age >= 18 years Confirmed early-onset severe sepsis, defined as: o---Objective evidence of infection likely to be caused by a bacterial or fungal pathogen o---Presence of at least 3 of 4 systemic inflammatory response syndrome (SIRS) o---Sepsis-associated organ dysfunct...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Temporal Lobe Epilepsy Patients will be included under the following circumstances: 1. Age between 18 to 80 years. 2. Written informed consent is given by the patient. 3. Epileptogenic focus in the temporal lobe or in the frontal lobe (unilateral or bilateral with dominant focus). 4. ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy patients currently taking divalproex direct release for any seizure and/or behavior disorder patients with intellectual disability other medications for co-morbid disease are permitted, provided no plans for changes in medication used for the treatment of the disorder are exp...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-65.0, Epilepsies Partial Patients who participated in study N01221 [NCT00280696] and completed the evaluation period and transition period or patients who participated in study N01020 [NCT00160615] Female patients during pregnancy, delivery and lactation, or suspected of pregnancy
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Drug Resistant Age from 18 to 65 Drug resistant epilepsy, partial seizure Epilepsy diagnosed for more than 2 years Epilepsy treated for more than 1 year with no change of treatment in the month before the enrolment Onset of cluster seizure in the 24 hours before enrolment For...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 2.0-65.0, Epilepsy Epilepsy with partial seizures Tonic clonic seizures Generalized seizures of Lennox-Gastaut Subjects whose seizures are easily recognizable at least one seizure per month and counts for 8 consecutive weeks prior to the start of the study drug Concurrent AEDs: Subjects taking c...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Epilepsy Epilepsy MRI incompatible Pregnancy
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Partial Seizures Male or Female who are diagnosed of partial seizure (simple partial, complex partial, partial seizure secondarily generalized) as defined in the international league of epilepsy classification of seizure Patients having a treatable cause of seizure, currently receiv...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Brain and Central Nervous System Tumors Seizure Unspecified Adult Solid Tumor, Protocol Specific Histologically confirmed solid tumor Pathological confirmation of brain metastasis is not required provided the clinical and neuroradiographic picture is typical Has had at least one prio...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-75.0, Metastatic Breast Cancer Patients diagnosed with metastatic breast cancer 2. Patients that either have received previous treatment with anthracyclines and/or taxanes or not (either as advance or in metastatic disease). 3. The patient is ambulatory with a functional ECOG < 2 status (se...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 12.0-75.0, Epilepsy Male or female subjects 12 to 75 years of age Subjects must have inadequately controlled partial onset epilepsy Subjects must be experiencing 2 to 40 seizures per 4-week period while being maintained on one or two standard AED(s) A history of status epilepticus in the 6 mont...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-75.0, Traumatic Brain Injury Cerebral Infarction Cerebral Hemorrhage One week following Traumatic Brain Injury Cerebro Vascular Accident Subsequent brain CT showed cerebral cortex injury A known ailment of the central nervous system Use of medications or illicit drugs that significantly af...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 21.0-999.0, Osteoarthritis Chronic Pain Subject is 21 years of age or older Subject is either not of childbearing potential OR subject must use an acceptable method of birth control if of childbearing potential Negative pregnancy test if female of childbearing potential Subject is in general goo...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Presurgical candidates with pharmacoresistant partial seizures despite optimal medical treatment and history of temporal lobe epilepsy Age above 18 years TIQ > 80 Able to give informed consent Average of 2 partial seizures per month during a baseline of 3 months. Recording o...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Depressive Disorder 18 years of age or older. 2. Diagnosis of Major Depressive Disorder validated by SCID. Subjects may meet for both melancholic and atypical depression per this protocol. 3. Have failed three or more antidepressant regimens during the current depressive episode with...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Epilepsy Seizures Patients must have seizures documented by appropriate clinical and laboratory studies . This criterion will be established by studies performed by the referring physicians, preliminary screening in the NINDS Clinical Epilepsy Section outpatient clinic, or if necessar...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-75.0, Primary Central Nervous System Lymphoma Patients must fulfill all the following to be eligible for admission for the study: 1. Histologically proven central nervous system lymphoma of brain parenchyma with or without leptomeningeal involvement. 2. No evidence of systemic lymphoma. 3. ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Depression Epilepsy Home address within 30 miles of Seattle Diagnosis of epilepsy (ICD-9 code 345.XX) Appointment in the UW REC or Neurology clinic in the past 2 years and currently enrolled in this clinic Current age older than 18 years Diagnosis of major depression, minor depressio...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-69.0, Partial Epilepsy Catamenial Epilepsy Diagnosis of epilepsy with POS with or without secondary generalized seizures according to the International League Against Epilepsy [ILAE] Classification of Epileptic Seizures (1981). Diagnosis should have been established by clinical history and ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-64.0, Epilepsy Referred to neurological institute at University Hospitals Case Medical Center for care of seizures/epilepsy Referred to neuropsychology laboratory for evaluation Participants must complete the routine check-in of all patients and sign consent and HIPAA forms Be, in the inves...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Blepharospasm Healthy volunteers (aged 18 or older) who are willing to participate Patients (aged 18 and older) with benign essential blepharospasm FOR Subjects with a history of neurological or psychiatric disorder, current use or a history of alcohol or drug abuse, psychiatric dis...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-90.0, Movement Disorders General for FMD patients Diagnosis of clinically definite FMD utilizing Fahn and Williams criteria. The diagnosis must be made by a neurologist Able to give informed consent Age 18 or older General for Caregivers Age 18 or older Able to give informed consent Takes c...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Tonic-clonic Seizure age 18 or older patient presenting to Grady Memorial Hospital's Emergency Department after having a tonic-clonic seizure (primary or secondarily generalized) within the last 4 hours Cause of seizure for reason for seizure is often undetermined at time of presenta...
2
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-70.0, Epilepsy diagnosis of Epilepsy completion of double blind trial taking other investigational drug than Lacosamide meeting withdrawal from double blind trial
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-70.0, Epilepsy Subject has a diagnosis of Epilepsy with Simple Partial Seizures (motor component) and or Complex Partial Seizures (with or without secondary generalization) Must be experiencing 2 to 40 seizures per 28-day period Stable dose of 1 or 2 marketed antiepileptic drugs Second Anti...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 10.0-75.0, Epilepsy probable or definite localization-related, primary generalized or symptomatic generalized epilepsy that is medically-refractory, as defined by treatment failure of at least 2 anti-epilepsy drugs at standard doses, despite medication compliance as determined by the treating ne...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Epilepsy Partial Seizure Disorder Epilepsies, Partial Complex Partial Seizure Disorder Subjects (male or female) must be > 18 years or ≤ 80 years of age, with a diagnosis of epilepsy with partial seizures, as defined in the International League Against Epilepsy (ILAE) classification o...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-60.0, Epilepsy Localization-related Epilepsy Infantile Spasms Lennox-Gastaut Syndrome Polymicrogyria Periventricular Heterotopias Current age from 4 weeks to 60 years Clear diagnosis of epilepsy, i.e., a lifetime history of two or more unprovoked seizures Age at first unprovoked seizure youn...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Schizophrenia Patients will fulfill DSM-IV-TR diagnostic for schizophrenia Patients reporting auditory hallucinations on average at least 5 times per day based on prospective assessment using a diary or handheld counter Patients are maintained on their psychotropic medication at stead...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy, Post-Traumatic Age >= 18 years old 2. Patient with severe brain injury defined as follow Initial Glasgow Coma score (assessed on the scene of the accident) <= 8 related to the brain injury Stage 2 to 4 on the TDM US TCDB classification 3. Initial brain CT scan performed wit...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Focal Dystonia Peripheral Nervous System Disease WITH FOCAL (ONLY) Age 18 years or older Presence of FD and no CRPS WITH CRPS (ONLY) Age 18 years or older Presence of CRPS and no FD WITH AND CRPS (CRPS + Age 18 years or older Presence of FD and CRPS in the same limb Concurrent signif...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Traumatic Brain Injury Epilepsy Moderate to severe traumatic brain injury, defined as one or more of the following: penetrating head wound seizure within the first hour after injury intracerebral hematoma or cortical contusion subdural or epidural hematoma Glasgow Coma Score <= 12 or...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Controls (20 Subjects) Ages 18-65, based on the usual ages of patients seen in the adult neurology services who are not likely to suffer from the exclusions (see below) History of seizures, faints, or any unexplained blackouts Use of neuroleptic medications or sedating doses...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.0-24.0, Infant, Newborn Hypoxia, Brain Hypoxia-Ischemia, Brain Encephalopathy, Hypoxic-Ischemic Hypoxic-Ischemic Encephalopathy Ischemic-Hypoxic Encephalopathy Infants born at 36 0/7ths weeks gestational age or greater (by best obstetrical estimate) Postnatal age between 6 and 24 hours followi...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Severe Sepsis Clinical evidence of infection requiring treatment with parenteral antibiotics Patients must meet multiple Systemic Inflammatory Response Syndrome (SIRS) Patients must meet for cardiovascular and/or respiratory dysfunction Sepsis (infection plus SIRS criteria) must be p...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Severe Trauma age 18 years or older, blunt or penetrating trauma and one or more of the following: systolic blood pressure less than 90 mmHg at the scene or within one hour of arrival to the Emergency Department, 2) base deficit ≥ -6 within one hour of admission, 3) ISS greater than ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Patients from both sexes, 18 to 65 years of age, diagnosed with simple or complex partial onset epileptic seizures defined according to the International League Against Epilepsy (ILAE) with a minimum of two crises within the 4 previous weeks, a stable treatment with two antie...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-75.0, Epilepsy Subjects from 16 to 75 years, both inclusive Well-characterized focal epilepsy or epileptic syndrome Subjects having at least 2 but not exceeding 40 partial onset seizures, whether or not secondarily generalized per 4 weeks during the 8-week Baseline Period Subjects on a stab...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-75.0, Epilepsy Subjects from 16 to 75 years, both inclusive Well-characterized focal epilepsy or epileptic syndrome Subjects having at least 2 but not exceeding 40 partial onset seizures, whether or not secondarily generalized per 4 weeks during the 8-week Baseline Period Subjects on a stab...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 7.0-55.0, Epilepsy Epilepsy, Temporal Lobe Partial Epilepsy FOR 1. Age 7-55 2. Documentation of localization-related epilepsy based on clinical, neuropsychological and imaging 3. Failure of seizures to respond to adequate therapy with at least two standard antiepileptic drugs 4. Willingness to b...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Temporal Lobe Epilepsy Unilateral or Bilateral Mesial Temporal lobe Epilepsy Age ≥ 18 years Global IQ ≥70 Failure of ≥ 2 AEDs approved for treatment of partial seizures, used alone or in combination at recommended dosages Average ≥ 3 seizure-days per month in prior 6 months during wh...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsy, Partial, Motor Epilepsy, Complex Partial Epilepsy, Simple Partial Focal Motor Epilepsy Must have completed the 14-week double-blind treatment phase of study must be willing/able to follow the restrictions and prohibitions of the protocol must be able to complete the patient...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-75.0, Treatment Resistant Depression Have a DSM-IV diagnosis of a major depressive episode 2. Are referred for or an outpatient course of ECT at the Alfred Hospital 3. Age 18-75 4. Have a Montgomery-Asberg Depression Rating Scale (MADRS) score of > 25 (moderate - severe depression) 5. Demon...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 4.0-999.0, Epilepsy iodiopathic focal epilepsy with cognitif deficit medical history of status epilepticus
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 5.0-999.0, Epilepsy Subjects are selected on the basis of intractability of their seizures to medical intervention by antiepileptic drugs and following a noninvasive workup that indicates the patient would be an excellent candidate for resective surgery Patient is under the age of 5
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy and Adults (18 years and older) of either gender who would otherwise be eligible for temporal lobe resection will be offered enrollment for randomization to RS or ATL. 1. Seizure type: Patients must have simple and/or complex partial seizures with or without secondary gener...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Epilepsy Male or female, age 18 History of intractable localization related/partial onset seizures and generalized tonic/clonic or tonic seizures defined according to International League Against Epilepsy (ILAE) classification as A history compatible with localization related partial ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Depression Mood Disorders Depressive Disorder Patients will be aged 18-65, have no significant neurologic history, must meet DSM-IV for a diagnosis of major depression and be free of antidepressant or other psychotropic medication for a minimum of two weeks before enrollment. If a sub...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-55.0, Epilepsy Epilepsy, Temporal Lobe Depression Depressive Disorder, Major Male and female subjects aged between 18 and 55 years Epileptic patients must have clinically documented partial seizures, in either the left or right temporal lobe, or generalized seizures with consistent EEG evid...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Partial Epilepsy Age 18-70 years old Reliable history of seizure semiology, EEG or EEG video telemetry confirming the diagnosis of partial epilepsy Seizure frequency of at least 6 complex partial seizures over the 9 weeks prior to enrollment, with no 3 week period with less than one s...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 20.0-90.0, Hemiplegia hemiplegia; unilateral weakness of sudden onset secondary to strokes or other brain lesions compatible with brain lesions confirmed by imaging studies bilateral weakness any history of intensive trauma of the shoulder, reported preexisting musculoskeletal disorder of the s...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 40.0-80.0, UPDRS PD patients with asymmetric disease aged 40 years or older, diagnosed as idiopathic PD according to the UK Brain Bank with Hoehn & Yahr stages II IV while "off" Participants on antidepressants should be at least 2 months on stable therapy Patients who have concomitant epilepsy,...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-55.0, Musculoskeletal Pain Signed and dated informed consent prior to participation Subjects in good health as determined by the Investigator Age 18-55 Willing to abstain from any physical therapy, hard physical work, exercise or sauna during the study observation period (Screening to Final...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, HIV Infection Liver Failure Evidence of Liver Transplantation Age ≥ 18 Documented HIV-1 infection, hepatitis B or C co-infection is allowed Plasma viral load at screening visit below 50 copies per mL for at least 6 months Patient with severe liver failure (Meld Score ≥ 15 and/or refr...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 0.5-999.0, HIV Infection Rheumatic Disease Cancer Transplant Pediatrics medically recommended influenza A(H1N1) immunization signed informed consent failure or refusal to provide sufficient blood for antibody determination
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-59.0, First Episode Psychosis Aged 18-59 years and meet DSM-IV diagnostic for first episode of schizophrenia, schizophreniform disorder, schizoaffective disorder or psychotic disorder NOS as assessed by using the Structured Clinical Interview for DSM-IV, research version Meeting DSM-IV for...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Adult Medically intractable epilepsy Min 4 complex partial seizures/ month Ability to give informed consent Underlying progressive neurological condition
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Metastatic Melanoma ENTRY Locally advanced or metastatic melanoma Measurable Histologically or cytologically confirmed Surgically incurable HLA-A2 positive and tumors that present HLA-A2.1/p53aa264-272 complexes PRIOR/CONCURRENT If prior Proleukin treatment, must have had clinical be...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Dermatologic Disease of Inpatients in Internal Medicine Patients will be eligible for enrolment if they fulfil the following 1. Male or female patients, age ? 18 years of age and 2. Hospitalised at the Division of Internal Medicine, University Hospital Zurich 3. Patients must be able...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 20.0-65.0, Opioids Use Age between 20-65 years old, all genders. 2. Psychiatry doctor diagnosed who met DSMIV-TR opioid addiction or opioid abusing. 3. Participants need to understand procedures and assays of this experiment. 4. Participants are willing to accept methadone substitutive abstainin...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy 65 years of age Normal IQ as estimated by the Wechsler Test of Adult Reading (WTAR) Able to give consent Able to live independently and complete activities of daily living Stable frequency of seizures. There is no minimum/maximum for the frequency of partial seizures. Those w...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 15.0-999.0, Partial Epilepsy medically intractable patial epilepsy confirmed by video-EEG recordings of epileptic seizures Depth EEG (Stereo-EEG) required to delineate the epileptogenic zone and define the surgical procedure full informed consent of the patient (or of his/ her legal representati...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsies, Partial The patient's treatment must be in accordance with the local marketing authorization (MA) for Vimpat® The decision to prescribe Vimpat® has to be made by the physician before and independently of his/her decision to the patient in the study The Vimpat® treatment s...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Depression Subjects for this study will meet the following 1. Age greater than or equal to 18 years. 2. Must be in accordance with the diagnostic of epilepsy and have taken antiepileptic drugs regularly at least for 6 months, which will not be changed recently. The duration ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-60.0, Epilepsy Seizures patients in whom seizures are not controlled by their antiseizure medication must have at least 2 seizures per month patients with cardiovascular problems that could be adversely affected by verapamil
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Acute Heart Failure A diagnosis of heart failure as defined by the presence of at least 1 symptom (dyspnea, orthopnea, or edema) AND 1 sign (rales on auscultation, peripheral edema, ascites, pulmonary vascular congestion on chest radiography) Prior clinical diagnosis of heart failure...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 15.0-999.0, Epilepsy Epilepsy patient over 15 years old who agrees with Informed Consent Form 2. Patient who has classifiable uncontrolled partial epilepsy according to International Classification of Epileptic Seizures. 3. Patient who has 3 ~ dozens of partial seizure (average more than once se...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Pathological Gambling Pathological gambling according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) History of a primary major psychiatric or cognitive disorder according to DSM IV apart from Pathological gambling Current alcohol ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-70.0, Epilepsy Seizure Disorders Ages 18 No serious or progressive medical illness A history of intractable partial seizures At least two complex partial or tonic clonic generalized seizures per month in the last two consecutive months MRI or EEG consistent with localization-related or part...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Alcohol Withdrawal Need for admission to hospital for acute alcohol withdrawal allergy to phenobarbital, lorazepam, age<18 or >65
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-40.0, Traumatic Brain Injury Stroke Headache PTSD Age 18 to 40 2. Able to give consent 3. Normal clinical examination for healthy subjects 4. Must be able to follow instructions and perform required tasks, and TBI patients must have the Mini-mental state examination (MMSE) score of 25 or ab...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy Patient has a clinical diagnosis of epilepsy requiring additional evaluation in an epilepsy monitoring unit (EMU). 2. Patient likely requires an EMU evaluation for a period of at least 3 days. 3. In the opinion of the Principal Investigator, the Patient is likely to have 3 s...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Major Depression Epilepsy Patients will be 20 males or females above the age of 18 with a current major depressive episode, as defined by DSM-IV and assessed on the MINI, of at least 4 weeks duration. 2. All subjects must have epilepsy, defined as the recurrence of seizures that are ...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-80.0, Epilepsy Well-characterized focal epilepsy/epileptic syndrome according to the 1989 International League Against Epilepsy (ILAE) classification Presence of an EEG reading compatible with the clinical diagnosis of focal epilepsy within the last 5 years Presence of a brain MRI/computed ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 8.0-999.0, Epilepsy Epilepsy, Temporal Lobe Partial Epilepsy To be eligible for entry into the study, candidates must meet all the following 1. Be 8 years of age or older with drug resistant epilepsy or tumor related epilepsy. 2. Have focal onset seizures. 3. Seizures must persist despite medica...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-65.0, Epilepsy Epilepsy, Temporal Lobe Partial Epilepsy Enrolled in protocol 01-N-0139 2. Age 18 to 65 3. Localization-related epilepsy diagnosed by standard clinical that has not responded to treatment with up to two standard antiepileptic drugs either sequentially or in combination. 4. Pa...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 17.0-70.0, Epilepsy participants from 17 to 70 years old history of Type I partial onset seizures (complex or simple with motor symptoms only) participants must have had electroencephalogram (EEG), magnetic resonance imaging (MRI) or computed tomography (CT) with results consistent with diagnosi...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 16.0-999.0, Epilepsy Focal Epilepsy Generalized Epilepsy Focal or generalized epilepsy diagnosis More than 3 recordable seizures per month BMI > 18,5 Not responded to at least three 3 AEDs years or older Motivated to complete the diet after thorough information Capable of recording seizures Capa...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Severe Sepsis Clinical diagnosis of Sepsis Mechanical ventilation due to acute pulmonary dysfunction One additional (second) acute sepsis-related organ dysfunction Pregnant women and nursing mothers Conditions or medications associated with an increased risk of bleeding/complication...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-80.0, Arthroplasty, Replacement, Knee Patients having total knee arthroplasty AsA 1-3 patients with a history of significant medical or psychiatric problems, BMI > 40, allergy to local anesthetic drugs, prior surgery in the inguinal region, neurological disease with sensory or motor defici...
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 40.0-999.0, Alzheimer's Disease Mild Cognitive Impairment Clinical diagnosis of Alzheimer's disease or Mild Cognitive Impairment must be able to swallow pills known or suspected bipolar disorder
0
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 17.0-999.0, Epilepsy Seizures Age 17 years Newly diagnosed epilepsy or history of first unprovoked, witnessed seizure Lack of consent provoked seizure due to obvious Acute lesion on CT (e.g. stroke, hemorrhage Provoked seizure due to obvious, chronic lesion on CT (e.g. vascular malformation, tu...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 18.0-999.0, Epilepsy years and above diagnosed by a neurologist as suffering from drug-resistant epilepsy (all types of seizures) outpatient in Neurology service of the investigation centres inhabitant in the Limousin region having signed the informed consent affiliated or profiting of a social ...
1
41 year old man with history of severe intellectual disability, CHF, epilepsy presenting with facial twitching on the right and generalized shaking in at his NH which required 20 mg valium to cease seizure activity. Per outside medical patient was felt to have focal epilepsy with secondary generalization, likely due to...
eligible ages (years): 4.0-65.0, Epilepsy Partial Seizures Patients of both sexes, aged between 04 and 65 years, remaining the feasibility of a legal guardian in accordance with need, able to understand and provide written informed consent and able to allow compliance at the treatment and the requirements of the proto...
1