title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Respiratory and other health effects reported in children exposed to the World Trade Center disaster of 11 September 2001. | Effects of the World Trade Center (WTC) disaster on children's respiratory health have not been definitively established. This report describes respiratory health findings among children who were < 18 years of age on 11 September 2001 (9/11) and examine associations between disaster-related exposures and respiratory... | 18,941,582 |
Case-control study of blood lead levels and attention deficit hyperactivity disorder in Chinese children. | Attention deficit/hyperactivity disorder (ADHD) and lead exposure are high-prevalence conditions among children. Our goal was to investigate the association between ADHD and blood lead levels (BLLs) in Chinese children, adjusting for known ADHD risk factors and potential confounding variables. We conducted a pair-match... | 18,941,585 |
Urinary porphyrin excretion in children is associated with exposure to organochlorine compounds. | Hexachlorobenzene (HCB) and other organochlorines induce porphyria cutanea tarda (PCT) in animal studies. Evidence in humans, however, is contradictory. In neonates and adults from a population historically highly exposed to HCB (Flix, Catalonia, Spain), no relation with PCT or with porphyrin excretion was found. We ai... | 18,941,586 |
The role of an aromatic group in remote chiral induction during conjugate addition of alpha-sulfonylallylic carbanions to ethyl crotonate. | The impact of a remote aromatic nucleus on the stereochemical outcome of the conjugate addition of alpha-sulfonylallylic carbanions to an alpha,beta-unsaturated ester was investigated. alpha-Regioselectivity coupled with anti-diastereoselectivity is accompanied by a prominent preference for relative configuration 3 ove... | 18,941,617 |
Incompetence of neutrophils to invasive group A streptococcus is attributed to induction of plural virulence factors by dysfunction of a regulator. | Group A streptococcus (GAS) causes variety of diseases ranging from common pharyngitis to life-threatening severe invasive diseases, including necrotizing fasciitis and streptococcal toxic shock-like syndrome. The characteristic of invasive GAS infections has been thought to attribute to genetic changes in bacteria, ho... | 18,941,623 |
Origination of the split structure of spliceosomal genes from random genetic sequences. | The mechanism by which protein-coding portions of eukaryotic genes came to be separated by long non-coding stretches of DNA, and the purpose for this perplexing arrangement, have remained unresolved fundamental biological problems for three decades. We report here a plausible solution to this problem based on analysis ... | 18,941,625 |
Cardiac autotransplantation for malignant or complex primary left-heart tumors. | Malignant or complex benign tumors of the left heart can present a formidable challenge for complete resection, due to anatomic inaccessibility. Cardiac autotransplantation (cardiac explantation, ex-vivo tumor resection, reconstruction, and reimplantation) was introduced for complex benign primary left-heart cardiac tu... | 18,941,651 |
Bonding properties and bond activation of ylides: recent findings and outlook. | The interaction of phosphorus and nitrogen ylides with metallic precursors has been examined from different points of view. The first one is related to the bonding properties of the ylides. Ylides with a unique stabilizing group bond through different atoms (the Calpha or the heteroatoms); while ylides with two stabili... | 18,941,652 |
Continuous particle separation in spiral microchannels using Dean flows and differential migration. | Microparticle separation and concentration based on size has become indispensable in many biomedical and environmental applications. In this paper we describe a passive microfluidic device with spiral microchannel geometry for complete separation of particles. The design takes advantage of the inertial lift and viscous... | 18,941,692 |
Physiological stress of high NH (4) (+) concentration in water column on the submersed macrophyte Vallisneria Natans L. | The submersed macrophyte, Vallisneria natans L., was cultured in laboratory with NH (4) (+) -enriched tap water (1 mg L(-1) NH(4)-N) for 2 months and the stressful effects of high ammonium (NH (4) (+) ) concentrations in the water column on this species was evaluated. The plant growth was severely inhibited by the NH (... | 18,941,702 |
Alzheimer's disease and other dementing conditions. | Dementia is a common and growing problem, with 20% of those over 80 years of age suffering from this disorder. The prospect of more effective treatments has caused an increasing demand for a more accurate and earlier diagnosis of different dementia syndromes. Neuroimaging techniques may have an important role in the cl... | 18,941,718 |
Tumours. | Detection of a brain lesion is the first diagnostic step in patients with symptoms and signs suggesting the presence of a brain tumour. Imaging is primarily done to prove or rule out the presence of such a lesion. The first diagnostic evaluation is based on neuroradiological imaging, and when the diagnosis of brain tum... | 18,941,724 |
[Adrenal tumors]. | Adrenal tumors can be primary or secondary entities. Primary tumors are able to secrete hormones which may cause significant effects clinically. Typical tumor-related adrenal diseases are Conn's syndrome (hyperaldosteronism), Cushing's syndrome (hypercortisolism), and pheochromocytoma (catacholamine excess). Primary ad... | 18,941,729 |
Focal adhesion kinase as an immunotherapeutic target. | Focal adhesion kinase (FAK) is a ubiquitously expressed non-receptor tyrosine kinase involved in cancer progression and metastasis that is found overexpressed in a large number of tumors such as breast, colon, prostate, melanoma, head and neck, lung and ovary. Thus, FAK could be an attractive tumor associated antigen (... | 18,941,742 |
Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation. | The two major aggrecanases involved in osteoarthritis (OA) are ADAMTS-4 and ADAMTS-5. Knock-out studies suggested that ADAMTS-5, but not ADAMTS-4, is the major aggrecanase in murine OA. However, studies of human articular cartilage suggest that ADAMTS-4 also contributes to aggrecan degradation in human OA. This study i... | 18,941,754 |
D3 lymphadenectomy using a medial to lateral approach for curable right-sided colon cancer. | The extended D3 lymphadenectomy using a medial to lateral (MtL) approach for the treatment of curable right-sided colon cancer is performed with a view to improving oncologic surgery outcomes. However, the feasibility and safety of this procedure has not been fully examined. The present study investigated the feasibili... | 18,941,759 |
Exacerbation of liver cirrhosis in pregnancy: a complex emerging clinical situation. | Pregnancy in women with liver cirrhosis is an infrequent situation. In general the incidence of cirrhosis in pregnancy is very low and it is estimated approximately about 1 in 5,950 pregnancies. We report a descriptive management of pregnancy in a woman suffering from chronic viral hepatitis B with D and C coinfection ... | 18,941,761 |
[Anxiety and depression in headache patients. The example of managed care of chronic headache patients in Bavaria]. | The prevalence of anxiety and depression and the influence of headache severity on these illnesses were examined in patients who were part of the managed care of headache in Bavaria. A total of 181 patients with headache were screened for anxiety and depression with the German version of the Hospital Anxiety and Depres... | 18,941,799 |
[Measurement of success of treatment for chronic back pain. Can general effects in an entire sample of patients with chronic back pain be transferred to specific effects in individuals?]. | The multimodal therapy has proved to be useful for the treatment of patients with chronic back pain. The aim of this methodical study was to test whether specific effects for the individual can be inferred from general effects of the entire sample, in order to define criteria for the success of treatment. These could b... | 18,941,800 |
Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp. | Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont-(4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyr... | 18,941,819 |
[Mechanical ventilation of morbidly obese patients in anaesthesia and intensive care]. | Sculptures from the Stone Age hint at the possibility that morbidly obese humans have always existed. Today, obesity represents a global epidemic with far-reaching consequences affecting health systems worldwide. Increasingly often, anaesthetists and intensivists are challenged with the treatment of extremely obese pat... | 18,941,825 |
Muscular and hepatic pollution biomarkers in the fishes Phycis blennoides and Micromesistius poutassou and the crustacean Aristeus antennatus in the Blanes Submarine Canyon (NW Mediterranean). | Submarine canyons are regarded as a sink for pollutants. In order to determine if this theory applied to deep-sea species from an important fishing ground (the Blanes submarine canyon) located in the NW Mediterranean, we sampled the commercial fish Phycis blennoides and Micromesistius poutassou and the crustacean Arist... | 18,941,829 |
Primary vaginal reconstruction at the time of pelvic exenteration for gynecologic cancer: morbidity revisited. | The aim of this study is to analyze our experience about the benefits and morbidity of primary vaginal reconstruction in pelvic exenteration. Over a 10-year period, 64 patients underwent a pelvic exenteration for gynecologic cancer, except for ovarian and fallopian cancer. Twenty-nine patients underwent pelvic exentera... | 18,941,843 |
Synergistic effect of Kalpaamruthaa on antiarthritic and antiinflammatory properties--its mechanism of action. | The present study was designed to evaluate the antiinflammatory properties of Kalpaamruthaa (KA) a modified indigenous Siddha formulation constituting Semecarpus anacardium nut milk extract (SA), Emblica officinalis (EO) and honey in acute and chronic antiinflammatory studies. A dose of 150 mg/kg b.wt. of SA and KA wer... | 18,941,878 |
Dimensional structure of the autism phenotype: relations between early development and current presentation. | The dimensional structure of higher functioning autism phenotype was investigated by factor analysis. The goal of this study was to identify the degree to which early symptoms of autism (measured using the ADI-R) could be predictive of the current symptoms of autism as identified using the ADOS, the adaptive behavior s... | 18,941,880 |
Lanthanum chloride suppresses hydrogen peroxide-enhanced calcification in rat calcifying vascular cells. | Lanthanum chloride (LaCl(3)) has been shown to retard the progression of established atherosclerotic lesions in animal models, and used as a calcium channel blocker in various cellular experiments. In this study, we assessed the role of lanthanum chloride (LaCl(3)) in H(2)O(2)-enhanced calcification in rat calcifying v... | 18,941,904 |
Potential for seed-mediated gene flow in agroecosystems from transgenic safflower (Carthamus tinctorius L.) intended for plant molecular farming. | Safflower has been transformed for field scale molecular farming of high-value proteins including several pharmaceuticals. Viable safflower seed remaining in the soil seed bank after harvest could facilitate seed and pollen-mediated gene flow. Seeds may germinate in subsequent years and volunteer plants may flower and ... | 18,941,919 |
Redefining ecological ethics: science, policy, and philosophy at Cape Horn. | In the twentieth century, philosophy (especially within the United States) embraced the notion of disciplinary expertise: philosophical research consists of working with and writing for other philosophers. Projects that involve non-philosophers earn the deprecating title of "applied" philosophy. The University of North... | 18,941,926 |
Rehabilitation of sensorimotor integration deficits in balance impairment of patients with stroke hemiparesis: a before/after pilot study. | Balance impairment in patients with stroke hemiparesis is frequently related to deficits of central integration of afferent inputs (somatosensory, visual, vestibular). Our aim was to evaluate whether balance exercises performed under various sensory input manipulations can improve postural stability and/or walking abil... | 18,941,933 |
Cerebral sinus venous thrombosis in a subject with thyrotoxicosis and MTHFR gene polymorphism. | We report a case of cerebral venous thrombosis (CVT) due to tyrotoxicosis in a patient with methylenetetrahydro-folate-reductase (MTHFR) gene polymorphism C677T, (genotype 677TT), in which discontinuation of intravenous heparin was followed by clinical and radiological worsening despite warfarin treatment. We discuss t... | 18,941,937 |
Unawareness of "illnesses": a case of right-sided hemiballism. | The Authors describe a non-demented patient who, after a left subthalamic haemorrhage causing hemiballism, was completely unaware of both neurological (i.e., dyskinesias) and non-neurological (i.e., cough) symptoms occurring after the stroke. In contrast, he was perfectly able to acknowledge pathological conditions aff... | 18,941,938 |
A novel heterozygous mutation in the NOTCH3 gene causing CADASIL. | Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an identifiable cause of inherited stroke among young adults, characterised by diffuse leukoencephalopathy with prominent involvement of the temporal poles and external capsule. The disease is caused by mutations in ... | 18,941,948 |
Interaction of articaine hydrochloride with prokaryotic membrane lipids. | Local anesthetics are the most commonly used drugs in dentistry, with a wide range of effects, including antimicrobial activity. High antimicrobial effects have recently been reported on oral microbes from articaine hydrochloride, revealed by the minimum inhibitory concentration and minimal bactericidal concentration. ... | 18,941,950 |
The classification of vigilance tasks in the real world. | The ability to generalise vigilance research to operational environments has been questioned, largely due to differences between laboratory research and real-world settings. The taxonomy of vigilance tasks proposed by Parasuraman and Davies (1977) represents an attempt to classify vigilance tasks so that tasks with sim... | 18,941,972 |
Validation of a three-dimensional hand scanning and dimension extraction method with dimension data. | A three-level experiment was developed to validate a 3-D hand scanning and dimension extraction method with dimension data. At the first level, a resin hand model of a participant was fabricated to test the repeatability of the dimension data obtained by the 3-D method. At the second level, the actual hand of that part... | 18,941,974 |
Sex-related differences in foot shape. | The purpose of the study was to investigate sex-related differences in foot morphology. In total, 847 subjects were scanned using a 3-D-footscanner. Three different analysis methods were used: (1) comparisons were made for absolute foot measures within 250-270 mm foot length (FL); (2) and for averaged measures (% FL) a... | 18,941,975 |
Effects of a feedback signal in a computer mouse on movement behaviour, muscle load, productivity, comfort and user friendliness. | To study the effects of a tactile feedback signal in a computer mouse on reduction of hovering behaviour and consequently on changes in muscle load, productivity, comfort and user friendliness, a comparative, experimental study with repeated measures was conducted. Fifteen subjects performed five trials with different ... | 18,941,979 |
Toxic effects of chlorpromazine on Carassius auratus and its oxidative stress. | Under laboratory conditions, ecotoxicological effects of chlorpromazine (CPZ) on freshwater goldfish (Carassius auratus) were examined using the toxic culture experiment. The results showed that the median lethal concentration (LC(50)) of CPZ toxic to Carassius auratus in 24, 48 and 96 h was 1.11, 0.43 and 0.32 mg/L, r... | 18,941,986 |
Level of contamination and impact of pesticides in cupped oyster, Crassostrea gigas, reared in a shellfish production area in Normandy (France). | Over the last decade, oysters in the Bay of Veys (Northwest France) have sporadically experienced significant summer mortality events which appear to be due to a combination of extrinsic and intrinsic factors. In the present work, the involvement of pesticides (as additional stressors) was investigated using both artif... | 18,941,988 |
Development of IC-ELISA for detection of organophosphorus pesticides in water. | Diethyl (carboxymethyl) phosphonate (DECP) was used as the hapten to develop an indirect competitive enzyme-linked immunosorbent assay (IC-ELISA) for detecting organophosphorus pesticides (OPs). Conjugator of DECP with bovin serum albumin (BSA) was used as the immunogen for producing the polyclonal antibodies (PcAbs). ... | 18,941,995 |
Sensitivity of intestinal fibroblasts to TNF-related apoptosis-inducing ligand-mediated apoptosis in Crohn's disease. | Strictures and fistulas are common complications of Crohn's disease (CD). Collagen deposit and fibroblast proliferation can contribute to their development. Tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) binds two pro-apoptotic (TRAIL-R1, TRAIL-R2) and three anti-apoptotic (TRAIL-R3, TRAIL-R4, o... | 18,942,021 |
Acute scrotal oedema complicating peritoneal dialysis. | A case of extraperitoneal leakage of dialysate producing massive acute scrotal oedema complicating peritoneal dialysis is presented. Important diagnostic features including select clinical images, the role of imaging modalities and appropriate management are discussed. | 18,942,023 |
Children's Color Trails Test 1 & 2: test-retest reliability and factorial validity. | This investigation examined the test-retest reliability and the factorial validity of the Children's Color Trails Test 1 & 2 (CCTT) using two distinct and independent studies and their respective research samples. The reliability of the CCTT was evaluated in a study with 6-12-year-old children (n = 54) strictly sel... | 18,942,031 |
Births resulting from oocyte cryopreservation using a slow freezing protocol with propanediol and sucrose. | The human mature oocyte is particularly sensitive to cooling and low temperatures in addition to freeze-thaw damage. The efficiency of oocyte cryopreservation including the pregnancy outcome is still low. The aim of our study is to briefly introduce our preliminary clinical results achieved with oocyte cryopreservation... | 18,942,028 |
Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T (1)H MRS imaging study. | Chronic fatigue syndrome (CFS) is a controversial diagnosis because of the lack of biomarkers for the illness and its symptom overlap with neuropsychiatric, infectious, and rheumatological disorders. We compared lateral ventricular volumes derived from tissue-segmented T(1)-weighted volumetric MRI data and cerebrospina... | 18,942,064 |
Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665. | Therapy for gastrointestinal stromal tumors (GIST) has changed significantly with the use of imatinib mesylate (IM). Despite the success of this drug in metastatic GIST, disease progression remains a perplexing clinical issue suggesting the need for multimodality management. There have been no prospective studies eithe... | 18,942,073 |
Surgical exposures for distal humerus fractures: a review. | The majority of distal humerus fractures have complex fracture patterns, with displaced articular segments, requiring operative intervention. The goals of surgery are anatomic reduction and rigid internal fixation via an operative approach that balances maximum required exposure with minimum soft tissue or bony disrupt... | 18,942,078 |
Dihydrotestosterone sensitises LNCaP cells to death induced by epigallocatechin-3-Gallate (EGCG) or an IGF-I receptor inhibitor. | Compelling evidence has accumulated for chemopreventive effects for the active component of green tea Epigallocatechin-3-Gallate (EGCG) particularly for prostate cancer (CaP). We have assessed interactions between the effects of EGCG and two main regulators of prostate cell function, dihydrotestosterone (DHT) and insul... | 18,942,120 |
Comparison of sirolimus-eluting stent and paclitaxel-eluting stent for long-term cardiac adverse events in diabetic patients: the Korean Multicenter Angioplasty Team (KOMATE) Registry. | There is some controversy on long-term cardiac outcomes between sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in diabetes mellitus (DM). We compared cardiac adverse events after SES and PES implantation in patients with DM over a period of 3 year. A total of 634 patients with DM treated with SES (n... | 18,942,123 |
Comparison of two transcatheter device strategies for occlusion of the patent ductus arteriosus. | The present study evaluates two transcatheter closure strategies utilized at a single center and makes recommendations for device selection when occluding the patent ductus arteriosus. A variety of devices are available for transcatheter closure of the patent ductus arteriosus (PDA) but no guidelines exist to guide ope... | 18,942,128 |
Generation and expression of a Hoxa11eGFP targeted allele in mice. | Hox genes are crucial for body axis specification during embryonic development. Hoxa11 plays a role in anteroposterior patterning of the axial skeleton, development of the urogenital tract of both sexes, and proximodistal patterning of the limbs. Hoxa11 expression is also observed in the neural tube. Herein, we report ... | 18,942,146 |
Wnt11r is required for cranial neural crest migration. | wnt11r is a recently identified member of the Wnt family of genes, which has been proposed to be the true Xenopus homologue to the mammalian wnt11 gene. In this study we have examined the role of wnt11r on neural crest development. Expression analysis of wnt11r and comparison with the neural crest marker snail2 and the... | 18,942,153 |
Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function. | Many major facilitator superfamily (MFS) transporters have similar 12-transmembrane alpha-helical topologies with two six-helix halves connected by a long loop. In humans, these transporters participate in key physiological processes and are also, as in the case of members of the organic anion transporter (OAT) family,... | 18,942,157 |
Kinetic modeling of ace operon genetic regulation in Escherichia coli. | A family of kinetic models has been developed that takes into account available experimental information on the regulation of ace operon expression in Escherichia coli. This has allowed us to study and analyze possible versions of regulation of the ace operon and to test their possibilities. Based on literature analysi... | 18,942,160 |
Prediction of loop regions in protein sequence. | We suggest an algorithm that inputs a protein sequence and outputs a decomposition of the protein chain into a regular part including secondary structures and a nonregular part corresponding to loop regions. We have analyzed loop regions in a protein dataset of 3,769 globular domains and defined the optimal parameters ... | 18,942,165 |
Chronic obstructive lung disease: perioperative management. | Inflammatory mediators play a major role in pulmonary and extra pulmonary manifestations of COPD. In the preoperative risk evaluation, composite scoring systems like ASA physical status are more efficacious than any single risk factor. Intraoperative ventilator graphics help in managing respiratory mechanics and reduci... | 18,942,241 |
Quadriplegia due to lead-contaminated opium--case report. | Utilization of lead-contaminated opium may lead to severe motor neuron impairment and quadriplegia. Forty years oriented old male, opium addict, was admitted to the ICU, with headache, nausea and abdominal pain, and weakness in his lower and upper extremities without definitive diagnosis. The past medical and occupatio... | 18,942,257 |
Global health priorities for developing countries: some equity and ethical considerations. | Although the need to make health priorities equitable in addressing health disparities among populations of the world is widely acknowledged, there are presently no clearcut mechanisms for achieving this goal at the global level. This paper highlights some of the limitations associated with priority setting based exclu... | 18,942,284 |
Outpatient pre-operative assessment in joint replacement surgery. | An anaesthetist-led outpatient pre-operative assessment (OPA) clinic was introduced in our unit in an effort to improve patient care and cost-effectiveness. To assess the efficiency of the clinic, 112 patients who attended the OPA clinic (attendance rate 98%) during the first year were assessed prospectively and compar... | 18,942,292 |
Endoscopic dacryocystorhinostomy. | A review of 45 patients who underwent endoscopic dacryocystorhinostomy (EDCR) from 1998 to 2005 was done. Only patients who had complete notes and had Jones tube removed at least three months before the study were included. Our experience with EDCR concludes it to be an easy, efficient treatment for nasolacrimal duct o... | 18,942,302 |
Insulinoma in Saudi Arabia: a twenty-year hospital study. | The study was designed to assess retrospectively clinical pattern of insulinoma at a national referral center in the Kingdom of Saudi Arabia. All cases of insulinoma recorded at King Khalid University Hospital Riyadh between January 1987 and December 2006 were reviewed. During the 20-year period five patients were seen... | 18,942,316 |
[Distinct clinical characteristics of inflammatory bowel disease in children younger than 5 years]. | In the last decades an increase in morbidity of inflammatory bowel disease, particularly of Crohn disease, in children has been observed. Assessment of clinical course and activity of inflammatory bowel disease in children younger than 5 years was the goal of the study. The study comprised 21 children aged 2 to 5 years... | 18,942,331 |
[Characteristic of bioamine-containing dental pulp structures under normal conditions and in pathology (a luminescence histochemical study)]. | Neurotransmitter biogenic amines (BA) are known to be important tissue differentiation inducers and promoters of mutual influence of the epithelial and mesenchymal structures during the process of tooth development in the antenatal period. The aim of this investigation was the study of BA-containing dental pulp structu... | 18,942,356 |
[S. P. Botkin--the founder of the domestic clinical gerontology]. | The first in the world large-scale gerontology investigation where 2620 elderly patients were examined was carried out by guidance professor S. P. Botkin in St.-Petersburg. The results were published in 1890 in the special book and consisted of 93 papers, including 102 tables. | 18,942,358 |
[Comparative study on the efficacy of cefuroxime, amoxycillin/clavulanic acid and fosfomycin in prophylaxis of nosocomial infections in oncologic patients after surgical operations]. | Rational antibiotic prophylaxis and antibacterial therapy of nosocomial infections is an actual problem in surgery. Improvement of antimicrobial chemotherapy and prophylaxis of nosocomial infections is of special importance in urgent cases in oncologic units. Data on the design of rational schemes for antibacterial pro... | 18,942,388 |
[Immunohistochemical markers as prognosticators in gynecologic oncology]. | Cyclooxygenase and particularly COX-2 expression impaired survival in patients operated on for endometrial adenocarcinoma of the uterus: 5-year overall and relapse-free survival in absence of expression was 92% and 88%, respectively, while in cases of distinct expression, it fell down to 52% and 48%, respectively (p = ... | 18,942,401 |
[A comparison of the pulsatile and nonpulsatile regimens of artificial blood circulation in operations of aortocoronary shunting]. | The work is based on a clinical-laboratory analysis of the pulsatile and non-pulsatile regimens of artificial blood circulation. During operation under investigation were indices of gases of the arterial and venous blood. They were compared with those of gases obtained using the monitor of transcutaneous gases of blood... | 18,942,431 |
[Peculiar features of the clinical picture of associated cranio-cerebral trauma]. | An investigation of the clinical picture of 4671 patients with associated cranio-cerebral traumas treated at the hospitals of Saint Petersburg in 2004 has shown that the clinical picture of associated traumas unlike that of isolated cranio-cerebral traumas have an atypical character with the development of pseudo-syndr... | 18,942,435 |
[Fetal osteomyelitis]. | The clinical course of fetal osteomyelitis was analyzed in 5 newborns. All of them had poorly manifested course of osteomyelitis, the absence of abscess formation and low information on traditional laboratory tests. The prenatal aspects of the intrauterine infection of the fetus responsible for the development of osteo... | 18,942,439 |
[Closed retrograde intubation of the small intestine]. | The article describes a method of closed retrograde intubation of the small intestine, indications for using and structure of the corresponding probe-intubator (industrial patent No 2290212). The application of the closed retrograde intubation of the small intestine was made in the clinic. | 18,942,447 |
[Patterns of biochemical disorders under exposure to neurotoxic chemicals varying in nature]. | The article covers results of examination of workers engaged into chemical production and contacting neurotoxic factors varying in nature. Findings are disorders of cholesterol metabolism in individuals engaged into vinylchloride and metallic mercury production, modified protein metabolism, activated lipid peroxidation... | 18,942,463 |
[Experimental modelling of toxic encephalopathy]. | The article covers problem of experimental biologic modelling of toxic encephalopathies. The authors represent major methodic approaches to modelling, criteria and methods to evaluate pathologic condition of CNS, present results of own research in creating models of toxic encephalopathies caused by metallic mercury and... | 18,942,466 |
Ethical, legal and social issues related to cell therapy. | The author analyses the implications of cell therapy from a legal study that regulates the use of embryonic material: the regulation of the obtaining of cells, of research with embryos and their research and therapeutic use. There is a detailed look at the provisions in the Convention on Human Rights and Biomedicine of... | 18,942,509 |
Clinical perspectives on portable do-not-resuscitate orders. | A do-not-resuscitate (DNR) order is a written medical order that documents a patient's wishes regarding resuscitation and, more specifically, the patient's desire to avoid cardiopulmonary resuscitation (CPR). A DNR order is one of the most important patient care directives that can be issued because it has dramatic and... | 18,942,535 |
Place of death for people with noncancer and cancer illness in South Australia: a population-based survey. | A large representative population survey of 9,500 households reports the association between place of death, diagnosis (cancer vs. noncancer), and use of palliative care services of terminally ill South Australians. Thirty-one percent (1,920) indicated that someone close to them had died of a terminal illness in the pr... | 18,942,564 |
Effects of feeding low protein diets to piglets on plasma urea nitrogen, faecal ammonia nitrogen, the incidence of diarrhoea and performance after weaning. | This study evaluated the effects of feeding pigs low protein (LP) diets for different lengths of time after weaning on indices of protein fermentation, the incidence of postweaning diarrhoea (PWD), growth performance, and total-tract apparent digestibility. Sixty weaner pigs weighing 6.1 +/- 0.13 kg (mean +/- SEM) were... | 18,942,582 |
Performance and tissue fatty acid profiles in veal calves fed diets supplemented with conjugated linoleic acids. | Three groups of six calves each were fed a milk replacer at 0.8 kg and a starter concentrate ad libitum. Calves of the control group received the basal diet supplemented with rapeseed oil at 10 g per kg of feed solids. Calves of treatment groups were fed diets supplemented with a synthetically produced oil containing 6... | 18,942,584 |
Potential for dissemination of the nonnative salmonid parasite Myxobolus cerebralis in Alaska. | Myxobolus cerebralis, the myxozoan parasite responsible for whirling disease in salmonids, was first introduced into the United States in 1958 and has since spread across the country, causing severe declines in wild trout populations in the intermountain western United States. The recent detection of the parasite in Al... | 18,942,590 |
Permanent tooth development in children with cleft lip and palate. | The purposes of this study were to: (1) quantify and compare permanent tooth development of cleft lip and palate (CLP) patients to age- and gender-matched controls; (2) relate these findings to cleft type and severity; and (3) examine delays in individual permanent maxillary teeth related to their proximity to the clef... | 18,942,600 |
Dutch primary schoolchildren's attitudes toward their dental appearance. | This study's purpose was to examine children's attitudes toward dental appearance and compare these with attitudes toward general health, body shape, grades in school, friends, money, and sports. The study also explored whether subjects reporting that they have attractive teeth believed themselves to have higher grades... | 18,942,606 |
Skin-sparing mastectomy: a survey based approach to defining standard of care. | Skin-sparing mastectomy (SSM) followed by immediate reconstruction has been advocated as an effective treatment option for patients with early-stage breast carcinoma. It markedly improves the quality of breast reconstruction through preservation of the natural skin envelope and a smaller incision. The purpose of this s... | 18,942,610 |
Changing concepts in the pathogenesis, evaluation, and management of solitary rectal ulcer syndrome. | The purpose of this study was to assess the impact of new technology on both the understanding of the underlying pathophysiology and treatment of solitary rectal ulcer syndrome (SRUS). This study is a retrospective review of patients with a histologic diagnosis of SRUS (1993 to 2007) complimented with a prospective dat... | 18,942,624 |
Management of high-grade splenic injury in children. | Using the National Trauma Databank, we identified 413 children (age < or = 14 years) who sustained high-grade blunt splenic injury (Abbreviated Injury Scale scores > or = 4) from 2001 to 2005. Overall mortality was 13.5 per cent. Early operation within 6 hours of injury (EOM) was performed in 128 patients (31%). ... | 18,942,629 |
100 robotic-assisted laparoscopic gastric bypasses at a community hospital. | Laparoscopic Roux-en-Y gastric bypass (LGB) is one of the most popular surgeries for morbid obesity. Robotic use is also on the rise. Data concerning outcomes is limited, hence the need for more information. The first 100 robotic-assisted bypasses by one surgeon in one institution were studied. Data obtained from clini... | 18,942,636 |
The value of endoscopic ultrasonography in predicting resectability and margins of resection for periampullary tumors. | Cure of pancreatic head and other periampullary neoplasms continues to be infrequent and is unattainable unless clear surgical margins are achieved during Whipple pancreaticoduodenectomy. Endoscopic ultrasonography (EUS) is a relatively recent gastrointestinal tumor imaging modality and may be superior to other techniq... | 18,942,637 |
Blunt thoracic aortic injury. | Blunt thoracic aortic injury (BAI) is a rare but often fatal injury that occurs with severe polytrauma. Immediate diagnosis and treatment of BAI are essential for a successful outcome. We reviewed our experience with 20 patients with BAI treated at a Level I trauma center between 1995 and 2006. The mean Injury Severity... | 18,942,639 |
Anterolateral thigh flap pedicle for interposition artery and vein grafts in head and neck reconstruction: a case report. | The selection of receiving vessels is one of the most critical steps in ensuring a successful outcome in microvascular surgery. The use of interposition grafts in microsurgery offers the surgeon valuable options when the free flaps vascular pedicles are too short to be anastomosed directly to the recipient vessels. Her... | 18,942,655 |
Burnout in nurses and physicians working at an oncology department. | Burnout is associated with decreased job performance and commitment, predicts stress-related health problems, and low career satisfaction. The specific objectives in our study were to assess the levels of burnout and to investigate the interrelationships between demographic characteristics and burnout health-care profe... | 18,942,658 |
The impact of follicular (FL) and other indolent non-Hodgkin's lymphomas (NHL) on work productivity-a preliminary analysis. | Although much is known about the efficacy, toxicity, and direct costs of treatment for follicular lymphoma (FL), there is no data assessing the impact of this diagnosis on the work productivity of affected individuals. We conducted a cross-sectional survey study of consecutive patients attending a malignant haematology... | 18,942,670 |
Living radical polymerization of acrylates mediated by 1,3-bis(2-pyridylimino)isoindolatocobalt(II) complexes: monitoring the chain growth at the metal. | A new type of mediator for cobalt(II)-mediated radical polymerization is reported which is based on 1,3-bis(2-pyridylimino)isoindolate (bpi) as ancillary ligand. The modular synthesis of the bis(pyridylimino)isoindoles (bpiH) employed in this work is based on the condensation of 2-aminopyridines with phthalodinitriles.... | 18,942,701 |
WebMTA: a web-interface for ab initio geometry optimization of large molecules using molecular tailoring approach. | A web-interface for geometry optimization of large molecules using a linear scaling method, i.e., cardinality guided molecular tailoring approach (CG-MTA), is presented. CG-MTA is a cut-and-stitch, fragmentation-based method developed in our laboratory, for linear scaling of conventional ab initio techniques. This inte... | 18,942,724 |
Theoretical study of electronic properties of organic photovoltaic materials. | It has been proved that fullerene derivatives, in which an oligophenylenevinylene (OPV) group is attached to C(60), present an interesting photophysical phenomenon and can be incorporated into photovoltaic cells. In these systems, the OPV acts as electron donor upon excitation, and then fullerene absorbs photoexcited e... | 18,942,732 |
CASSCF and multireference CI with singles and doubles study of low-lying valence and Rydberg states of 2H-tetrazole. | Complete active space self-consistent field (CASSCF) and multireference CI with singles and doubles (MR-CISD) calculations [including extensivity corrections, at MR-CISD+Q and multireference averaged quadratic coupled cluster (MR-AQCC) levels] have been performed to characterize the low-lying valence and the Rydberg st... | 18,942,735 |
Pouchitis, similar to active ulcerative colitis, is associated with impaired butyrate oxidation by intestinal mucosa. | Healthy colonic mucosa uses butyrate as the major energy source. In ulcerative colitis (UC) butyrate oxidation has been shown to be disturbed, but it remains unclear whether this is a primary defect. The aim of this study was to measure mucosal butyrate oxidation in UC (involved and noninvolved colon) and in pouchitis ... | 18,942,762 |
Artificial chemokines: combining chemistry and molecular biology for the elucidation of interleukin-8 functionality. | How can we understand the contribution of individual parts or segments to complex structures? A typical strategy to answer this question is simulation of a segmental replacement followed by realization and investigation of the resulting effect in structure-activity studies. For proteins, this problem is commonly addres... | 18,942,784 |
Covalent bond fragmentation suitable to describe solids in the fragment molecular orbital method. | To improve the accuracy of the fragment molecular orbital method (FMO), we introduce a new fragmentation scheme based on using frozen orbitals to describe fractioned bonds. By applying this scheme to a set of polyalanine systems of up to 40 residues for the alpha-helix and beta-strand isomers, we established its accura... | 18,942,816 |
Clustering and classifying diverse HIV entry inhibitors using a novel consensus shape-based virtual screening approach: further evidence for multiple binding sites within the CCR5 extracellular pocket. | HIV entry inhibitors have emerged as a new generation of antiretroviral drugs that block viral fusion with the CXCR4 and CCR5 membrane coreceptors. Several small molecule antagonists for these coreceptors have been developed, some of which are currently in clinical trials. However, because no crystal structures for the... | 18,942,828 |
Preparation and biological properties of a melibiose binding lectin from Bauhinia variegata seeds. | A dimeric 64-kDa melibiose-binding lectin was isolated from the seeds of Bauhinia variegata. The isolation procedure comprised affinity chromatography on Affi-gel blue gel, ion exchange chromatography on Mono Q, and gel filtration on Superdex 75. The lectin was adsorbed on the first two chromatographic media. Its hemag... | 18,942,841 |
Analyzing the catalytic mechanism of the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. | In order to gain insight into the catalytic mechanism of Fe-type nitrile hydratases (NHase), the pH and temperature dependence of the kinetic parameters k cat, K m, and k cat/ K m along with the solvent isotope effect were examined for the Fe-type NHase from Comamonas testosteroni Ni1 ( CtNHase). CtNHase was found to e... | 18,942,853 |
Formation and characterization of fluid lipid bilayers on alumina. | Fluid lipid bilayers were deposited on alumina substrates with the use of bubble collapse deposition (BCD). Previous studies using vesicle rupture have required the use of charged lipids or surface functionalization to induce bilayer formation on alumina, but these modifications are not necessary with BCD. Photobleachi... | 18,942,863 |
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