title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Critical analysis of the 4-hour A&E policys impact on elderly patients. | Government evaluations of the 4-hour waiting time policy show an overall improvement in accident and emergency (A&E) waiting times. However, the audit results shadow the policy's impact on age groups, which make it difficult to determine the policy's impact on older people, who are the largest and most vulnerable s... | 18,946,398 |
[Alveolo-interstitial pneumonia due to Temozolamide]. | Temozolomide is an alkylating agent approved for treatment of glioblastoma in association with radiotherapy. We report the case of a 56 year old woman presenting with alveolo-interstitial pneumonia after treatment with Temozolomide. Initially she received induction treatment with Temozolomide and concomitant radiothera... | 18,946,417 |
New devices and techniques for airway management. | Innovation over the past 25 years in the field of the airway management has led to the proliferation of new and improved techniques and devices. It is important to emphasize that the definition of a failed airway must include the inability to maintain acceptable oxygenation and not only the evidence of unsuccessful lar... | 18,946,431 |
Fixed drug eruptions due to cotrimoxazole. | This prospective study on Fixed Drug Eruption (FDE) was carried out between January 2003 to December 2006 in Dermatology department of Mymensingh Medical College Hospital & private chambers. This study was carried out with an objective to see the specific site of involvement and other clinical parameters in FDE due... | 18,946,439 |
Effects of deep heat therapy on the patients with chronic low back pain. | A randomized clinical trial was conducted in the Department of Physical Medicine & Rehabilitation, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, from 1st April 2006 to 31st March 2007. A total of 102 patients of Chronic LBP were included in the study. Out of them, 42 (41.2%) were male and 60 (58.8... | 18,946,448 |
Clinical profile, management and outcome of lupus. | Systemic Lupus Erythematosus (SLE) is a disease of many faces and great mimicry. Women of child bearing ages are the potential candidates for this disease though it may occur in any age and sex group and the clinical manifestations do not vary with sex differentiation. Etiology of SLE is still to be defined and it has ... | 18,946,454 |
Crosstalk between small GTPases and polarity proteins in cell polarization. | Cell polarization is crucial for the development of multicellular organisms, and aberrant cell polarization contributes to various diseases, including cancer. How cell polarity is established and how it is maintained remain fascinating questions. Conserved proteins of the partitioning defective (PAR), Scribble and Crum... | 18,946,474 |
From cells to organs: building polarized tissue. | How do animal cells assemble into tissues and organs? A diverse array of tissue structures and shapes can be formed by organizing groups of cells into different polarized arrangements and by coordinating their polarity in space and time. Conserved design principles underlying this diversity are emerging from studies of... | 18,946,477 |
Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration. | Apolipoprotein E receptor 2 (ApoER2), very low-density lipoprotein receptor (VLDLR), and Dab1 are the main components of the Reelin signalling cascade. Reelin is the sole ligand defined so far in signalling through this pathway. Postnatal migration of neuronal precursors from the subventricular zone (SVZ) to the olfact... | 18,946,489 |
Long-lasting molecular changes in human skin after repetitive in situ UV irradiation. | It is known that UV modulates the expression of paracrine factors that regulate melanocyte function in the skin. We investigated the consequences of repetitive UV exposure of human skin in biopsies of 10 subjects with phototypes 2-3.5 taken 1-4 years later. The expression of melanogenic factors (TYR, MART1, MITF), grow... | 18,946,495 |
Towards systems biology of heterosis: a hypothesis about molecular network structure applied for the Arabidopsis metabolome. | We propose a network structure-based model for heterosis, and investigate it relying on metabolite profiles from Arabidopsis. A simple feed-forward two-layer network model (the Steinbuch matrix) is used in our conceptual approach. It allows for directly relating structural network properties with biological function. I... | 18,946,548 |
Short-term effects of irbesartan treatment on microalbuminuria in patients with normotensive type 2 diabetes. | To observe the short-term effects of irbesartan treatment on microalbuminuria in patients with normotensive type 2 diabetes. A total of 40 normotensive type 2 diabetes patients (mean age 55.1+/-11.4 years) who had microalbuminuria were included in this non-comparative and prospective research study. The study took plac... | 18,946,564 |
Prometheus' spirit: quality survival in advanced hepatocellular carcinoma after gemcitabine and cisplatin-based chemotherapy. | In advanced virus-induced hepatocellular carcinoma (HCC) associated with cirrhosis, the average survival is four months. We report a 56-year-old man with a large-volume advanced HCC, in whom gemcitabine and cisplatin-based chemotherapy resulted in near-complete regression, and quality survival of 24 months. | 18,946,603 |
Beneficial effects of Annona squamosa extract in streptozotocin-induced diabetic rats. | The present study investigated the possible therapeutic effects of Annona squamosa (A. squamosa) extract on certain biochemical markers in streptozotocin (STZ)-induced diabetes mellitus in rats. The effects of an aqueous extract of A. squamosa leaves on blood glucose, insulin, C-peptide, albumin, albumin/globulin ratio... | 18,946,614 |
Blistering erysipelas: not a rare entity. | Soft tissue infections are common, but erysipelas, especially its blistering feature, is an under-recognised entity. There have been few reports of blistering erysipelas. We aim to describe the clinical characteristics, management and the risk factors for erysipelas in 20 patients admitted in a tertiary hospital in Sin... | 18,946,616 |
Anatomical variations of the thyroid gland: possible surgical implications. | The organogenesis of the thyroid gland in humans is often disturbed, leading to a variety of morphological variations of the gland, such as hypoplasia, ectopy, hemiagenesis and agenesis. As the morphological variations are usually diagnosed incidentally during examination for other thyroid gland diseases, the true inci... | 18,946,620 |
Clinics in diagnostic imaging (124). Multiple enchondromatosis in Ollier disease. | A three-year-old girl presented with slow-growing swellings at the left foot and upper right humerus. Radiographs show multiple enchondromas in both feet, proximal humeri and scapulae, as well as at multiple sites in the hands, distal forearm bones and pelvis, in keeping with multiple enchondromatosis in Ollier disease... | 18,946,621 |
Iron transport in Francisella in the absence of a recognizable TonB protein still requires energy generated by the proton motive force. | The mechanism of iron transport in Francisella is still a puzzle since none of the sequenced Francisella strains appears to encode a TonB protein, the energy transducer of the proton motive force necessary to act on the bacterial outer membrane siderophore receptor to allow the internalization of iron. In this work we ... | 18,946,633 |
Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution. | Differential BDNF gene (BDNF) promoter use leads to protein isoforms differing by 8 or 15 N-terminal residues (BDNF1 and BDNF2) whose regulation and function are not completely understood versus the well-known 247-aa BDNF "short" form. To describe how BDNF isoform levels were regulated by chronic drug use, we measured ... | 18,946,637 |
[Identification of lung architecture using HRCT]. | The pulmonary interstitium is divided into different compartments, with the secondary pulmonary lobule representing the smallest subunit surrounded by connective tissue. Identification of the lobular architecture is a prerequisite for categorizing the broad spectrum of pulmonary interstitial diseases into distinct patt... | 18,946,649 |
[From end-organ disease to a classifiable bladder pain syndrome: paradigm shift in the understanding of urological pain syndromes exemplified by the condition currently called interstitial cystitis]. | Growing clinical and scientific data imply that the condition currently called interstitial cystitis is not just a mere bladder end-organ disease but that the symptoms perceived to be related to the bladder are rather one aspect of a complex pelvic pain syndrome. The term bladder pain syndrome/interstitial cystitis (BP... | 18,946,652 |
Acute tryptophan depletion and self-injurious behavior in aggressive patients and healthy volunteers. | An association between serotonin (5-HT) activity and self-injurious (i.e., self-aggressive) behavior across the spectrum of lethality (from self-mutilation through completed suicide) is a well-replicated finding. Studies to date, however, have relied on nonexperimental designs to examine this relationship, limiting the... | 18,946,662 |
Element-tagged immunoassay with inductively coupled plasma mass spectrometry for multianalyte detection. | The multianalyte immunoassay approach is currently attracting increasing attention due to its high sample throughput, short assay time, low sample consumption and reduced overall cost per assay. This paper reviews progress in the field of multianalyte immunoassays using inductively coupled plasma mass spectrometry, as ... | 18,946,666 |
A novel medium for the isolation of N-acylhomoserine lactone-degrading bacteria. | A novel chemically defined medium, named KG medium, supplemented with N-3-oxo-hexanoylhomoserine lactone (3-oxo-C6-HSL), an acylhomoserine lactone (AHL) used as signalling molecules in Gram-negative bacterial cell-to-cell communication, as the sole source of carbon and nitrogen, was designed and successfully used for t... | 18,946,694 |
Evolution in biological and nonbiological systems under different mechanisms of generation and inheritance. | The majority of definitions of life and evolution include the notion that part of an organism has to be copied to its offspring and that this includes some form of coded information. This article presents the thesis that this conception is too restrictive and that evolution can occur in systems in which there is no cop... | 18,946,696 |
Wear analysis in THA utilizing oxidized zirconium and crosslinked polyethylene. | Oxidized zirconium, a material with a ceramic surface on a metal substrate, and highly cross-linked polyethylene are two materials developed to reduce wear. We measured in vivo femoral head penetration in patients with these advanced bearings. We hypothesized the linear wear rates would be lower than those published fo... | 18,946,711 |
Relapsing polychondritis--case series from South India. | Relapsing polychondritis (RP) is a rare recurring inflammatory disorder with variable clinical course. It has been described mainly in Caucasian population. Reports from other ethnic groups are few. We report seven cases of relapsing polychondritis in south Indian population. In between 1995 and 2008, seven patients fu... | 18,946,713 |
A tale of three acaropathogenic fungi in Israel: Hirsutella, Meira and Acaromyces. | We review published and unpublished studies conducted in Israel with six acaropathogenic fungi, assayed in order to control the citrus rust mite, Phyllocoptruta oleivora (Ashmead) (CRM). Hirsutella thompsonii Fisher was introduced twice, killed 80-90% of the exposed mites, but due to its requirements for near-saturatio... | 18,946,714 |
Technical feasibility of transperineal MR-guided prostate interventions in a low-field open MRI unit: canine study. | Magnetic resonance imaging (MRI) provides superior visualization of the prostate, its substructure, surrounding tissues, and, most important, focal lesions or cancer. The purpose of our canine study was to demonstrate the feasibility of a low-field (0.35 T) transperineal system that enables precise MR image guidance of... | 18,946,728 |
Low doses of cholestyramine in the treatment of hyperthyroidism. | The enterohepatic circulation of thyroid hormones is increased in thyrotoxicosis. Bile-salt sequestrants bind thyroid hormones in the intestine and thereby increase their fecal excretion. Based on these observations, the use of cholestyramine has been tried. The present study evaluates the effect of low doses of choles... | 18,946,743 |
Androgen receptor expression in breast cancer: relationship with clinicopathological factors and biomarkers. | Breast cancer is a hormone-dependent tumor. Most breast cancer cells have an androgen receptor (AR), but the clinical value of AR expression is unclear. AR expression was evaluated in 227 primary breast cancers using immunohistochemistry. The relation of AR expression to clinicopathological factors and biomarkers was a... | 18,946,753 |
Congenital vulvar lymphangioma circumscriptum. | Lymphangioma circumscriptum (LC) is a defect of lymphatic channels in the deep dermis and subcutaneous layers, characterized by grouped vesicles. This disorder rarely occurs in vulvar sites. We present a rare case of LC in a 72-year-old patient who presented with a vulvar mass and ipsilateral leg edema. | 18,946,758 |
A single mutation at lysine 241 alters expression and trafficking of the D2 dopamine receptor. | Ubiquitination of G protein-coupled receptors has been identified to regulate receptor signal transduction including agonist-induced internalization and sorting of internalized receptor for degradation or for recycling. Using co-immunoprecipitation and immunoblot analysis, I found that the membrane-associated D(2) dopa... | 18,946,766 |
Biological specificity of visceral adipose tissue and therapeutic intervention. | With excess energy storage, obesity develops, leading to increased risk for type 2 diabetes and cardiovascular diseases. The distribution of body fat appears to be even more important than the total amount of fat. Abdominal and, in particular, visceral adiposity is strongly linked to insulin resistance, type 2 diabetes... | 18,946,788 |
The development of an instrument for evaluating clinical teachers: involving stakeholders to determine content validity. | Research indicates that the quality of supervision strongly influences the learning of medical students in clinical practice. Clinical teachers need feedback to improve their supervisory skills. The available instruments either lack a clear theoretical framework or are not suitable for providing feedback to individual ... | 18,946,815 |
Advances in automatic, manual and microwave-assisted solid-phase peptide synthesis. | Solid-phase strategies speed up the production of both short- and long-sequence peptides compared with solution methodologies. Therefore, solid-phase peptide synthesis (SPPS), proposed by Merrifield in the early 1960s, contributed to the 'Peptide Revolution' in the fields of diagnostics, and drug and vaccine developmen... | 18,946,841 |
Aryl-aryl crosss-couplings that avoid the preparation of haloaromatics. | Advances in the development of cross-coupling protocols that avoid haloaromatics are reviewed. Most of the reports that are discussed appeared in the literature within the past 2 years and describe either alternatives to halogenated electrophiles or halogen-free preparations of the organometallic partners. However, whi... | 18,946,848 |
Sirolimus-eluting and paclitaxel-eluting stents for the treatment of coronary bifurcations. | The aim of the study was to compare the outcomes of sirolimus-eluting (SES) and paclitaxel-eluting (PES) stent implantation in coronary bifurcations treated with either a 1-stent or 2-stent strategy. The study used a retrospective cohort analysis of consecutive de novo bifurcations, excluding left main, treated with SE... | 18,946,894 |
Samuel A. Levine and the history of grading systolic murmurs. | Murmurs were described first by Laennec in 1819, after which the significance of a murmur became a matter of debate. By the late 19th century, many physicians regarded systolic murmurs as "organic," whereas others believed that they were often "functional." Samuel Levine became a central figure in separating functional... | 18,946,930 |
Transfusion management using a remote-controlled, automated blood storage. | Generally, the safety of transfusion terapies for patients depends in part on the distribution of the blood products. The prevention of adverse events can be aided by technological means, which, besides improving the traceability of the process, make errors less likely. In this context, the latest frontier in automatio... | 18,946,954 |
[Study of expression of beta-III tubulin in human eye tissues during prenatal development]. | Expression of beta-III tubulin, a marker protein of early neuronal cells, was studied by molecular genetic and immunochemical techniques. The study was performed with human eyes in the 8.5th to 27-28th weeks of prenatal development. Expression of beta-III tubulin was detected immunochemically in the retina and lens fib... | 18,946,987 |
Iodine deficiency in 2007: global progress since 2003. | Iodine deficiency is a global public health problem, and estimates of the extent of the problem were last produced in 2003. To provide updated global estimates of the magnitude of iodine deficiency in 2007, to assess progress since 2003, and to provide information on gaps in the data available. Recently published, nati... | 18,947,032 |
Simulation model of the impact of biofortification on the absorption of adequate amounts of zinc and iron among Mexican women and preschool children. | Biofortification is an agricultural process that attempts to increase the iron and zinc content of staple food crops. Improving the absorption of zinc and iron could contribute to reducing the high rates of deficiency of these micronutrients in developing-country settings. To simulate the effects of biofortification of... | 18,947,033 |
Prostate cancer hope. | A new drug has the potential to improve treatment for men with prostate cancer. | 18,947,077 |
Retrospective clinical and molecular analysis of conditioned laboratory dogs (Canis familiaris) with serologic reactions to Ehrlichia canis, Borrelia burgdorferi, and Rickettsia rickettsii. | Dogs are susceptible to different tickborne infections, including members of the Anaplasmataceae (Ehrlichia canis, E. ewingii, E. chaffeensis, Anaplasma phagocytophilum, A. platys), Borrelia burgdorferi, and Rickettsia rickettsii. These diseases can manifest with clinical signs including fever, anorexia, malaise, lamen... | 18,947,166 |
Diagnosis and treatment of pulmonary arterial hypertension and atrial fibrillation in an adult chimpanzee (Pan troglodytes). | This report describes the diagnosis and treatment of pulmonary arterial hypertension (PAH) in an adult male captive chimpanzee. Although cardiovascular disease in general is common in human and great apes, diagnosis and treatment of PAH in nonhuman primates are uncommon. In the case we present, the adult chimpanzee was... | 18,947,173 |
Structural and photophysical characterization of multichromophoric pyridylporphyrin-rhenium(i) conjugates. | Four porphyrin-Re(I) conjugates, in which a pyridylporphyrin chromophore is directly coordinated to the electron-acceptor fragment [ fac-Re(CO) 3(bipy)] (+), were prepared: the dimeric and pentameric compounds [ fac-Re(CO) 3(bipy)(4'MPyP)](CF 3SO 3) ( 1) (4'MPyP = 4'-monopyridylporphyrin) and [ fac-{Re(CO) 3(bipy)} 4(m... | 18,947,175 |
Simultaneous detection of pH changes and histamine release from oxyntic glands in isolated stomach. | Real-time simultaneous detection of changes in pH and levels of histamine over the oxyntic glands of guinea pig stomach have been investigated. An iridium oxide pH microelectrode was used in a potentiometric mode to record the pH decrease associated with acid secretion when the sensor approached the isolated tissue. A ... | 18,947,199 |
Optically active supramolecular complexes of water-soluble achiral polythiophenes and folic acid: spectroscopic studies and sensing applications. | Optically active supramolecular complexes of water-soluble achiral polythiophene (PT) derivatives, PMTPA or PMTEA (Chart 1), and folic acid have been prepared; and the complex formation processes have been studied by absorption, emission, and circular dichroism (CD) spectroscopies. The complexes exhibited unique split-... | 18,947,207 |
Water-in-model oil emulsions studied by small-angle neutron scattering: interfacial film thickness and composition. | The ever-increasing worldwide demand for energy has led to the upgrading of heavy crude oil and asphaltene-rich feedstocks becoming viable refining options for the petroleum industry. Traditional problems associated with these feedstocks, particularly stable water-in-petroleum emulsions, are drawing increasing attentio... | 18,947,210 |
Analytic calculations of vibrational hyperpolarizabilities in the atomic orbital basis. | We present an analytic scheme for the calculation of pure vibrational contributions to linear and nonlinear optical properties such as the polarizability and the first and second hyperpolarizabilities. The formalism is fully expressed in terms of a perturbation- and time-dependent atomic orbital basis, using the elemen... | 18,947,217 |
Bonded exciplex formation: electronic and stereoelectronic effects. | As recently proposed, the singlet-excited states of several cyanoaromatics react with pyridine via bonded-exciplex formation, a novel concept in photochemical charge transfer reactions. Presented here are electronic and steric effects on the quenching rate constants, which provide valuable support for the model. Additi... | 18,947,220 |
Dialkylphosphates (DAPs) in fruits and vegetables may confound biomonitoring in organophosphorus insecticide exposure and risk assessment. | Trace residues of organophosphorus (OP) pesticides are associated with fruits and vegetables that have been sprayed with those OP pesticides to guard against insect pests. Human dietary exposure to these OP pesticides is commonly estimated by measuring the amount of OP metabolites in urine, assuming a stoichiometric re... | 18,947,233 |
Update on oral cyanocobalamin (vitamin B12) treatment in elderly patients. | The objective of this review is to evaluate the usefulness of oral cobalamin (vitamin B12) treatment in elderly patients. PubMed was systematically searched for English and French articles published from January 1990 to January 2007. Prospective randomized studies (n=3), a systematic review by the Cochrane group (n=1) ... | 18,947,260 |
Use of flowable composites for orthodontic bracket bonding. | To test the bonding characteristics of four flowable composites for orthodontic bracket bonding. Metal brackets were bonded to acid-etched human enamel using four flowable composites (Grandio Flow, GF; UniFil Flow, UF; UniFil LoFlo Plus, UL; and DenFil Flow, DF), an orthodontic bonding system (Transbond XT, TX), and a ... | 18,947,267 |
Occlusal hypofunction induces atrophic changes in rat gingiva. | To clarify the influence of occlusal hypofunction on the integrity of gingival tissue and gingival extracellular matrix biosynthesis. Thirteen-week-old male Wistar rats were divided into two groups. To eliminate occlusal forces, all the right maxillary molars were extracted in the hypofunctional group. The control grou... | 18,947,276 |
Primary myelofibrosis: update on definition, pathogenesis, and treatment. | Primary myelofibrosis (PMF) is a clonal stem cell disorder that manifests clinically as anemia, splenomegaly due to extramedullary hematopoiesis, leukoerythroblastosis, and constitutional symptoms, which are the clinical hallmarks of PMF. Within the past three years it has been determined that a single, recurrent, soma... | 18,947,294 |
Biomarkers for prostate cancer. | The development of biomarkers for prostate cancer screening, detection, and prognostication has revolutionized the management of this disease. Prostate-specific antigen (PSA) is a useful, though not specific, biomarker for detecting prostate cancer. We review the literature on prostate cancer biomarkers, including seru... | 18,947,298 |
Polycystic kidney disease. | A number of inherited disorders result in renal cyst development. The most common form, autosomal dominant polycystic kidney disease (ADPKD), is a disorder most often diagnosed in adults and caused by mutation in PKD1 or PKD2. The PKD1 protein, polycystin-1, is a large receptor-like protein, whereas polycystin-2 is a t... | 18,947,299 |
Transcriptome alterations due to physiological normoxic (2% O2) culture of human embryonic stem cells. | Human embryonic stem cells (hESCs) hold great promise therapeutically. In order to deliver on this promise the correct defined conditions for long-term propagation must first be established. Researchers have now provided reports describing the benefits of culturing hESCs in physiologically approximate levels of oxygen.... | 18,947,306 |
Ophthalmic imaging today: an ophthalmic photographer's viewpoint - a review. | Ophthalmic imaging has changed dramatically since the 1960s with increasingly complex technologies now available. Arguably, the greatest changes have been the development of the digital camera and the speed, processing power and storage of electronic data. Already, ophthalmic practices in many major institutions overse... | 18,947,332 |
Looking while unhappy: mood-congruent gaze in young adults, positive gaze in older adults. | Recent findings that older adults gaze toward positively valenced stimuli and away from negatively valenced stimuli have been interpreted as part of their attempts to achieve the goal of feeling good. However, the idea that older adults use gaze to regulate mood, and that their gaze does not simply reflect mood, stands... | 18,947,348 |
Individual differences in delay discounting: relation to intelligence, working memory, and anterior prefrontal cortex. | Lower delay discounting (better self-control) is linked to higher intelligence, but the basis of this relation is uncertain. To investigate the potential role of working memory (WM) processes, we assessed delay discounting, intelligence (g), WM (span tasks, 3-back task), and WM-related neural activity (using functional... | 18,947,356 |
Vascular involvement in rheumatic diseases: 'vascular rheumatology'. | The vasculature plays a crucial role in inflammation, angiogenesis, and atherosclerosis associated with the pathogenesis of inflammatory rheumatic diseases, hence the term 'vascular rheumatology'. The endothelium lining the blood vessels becomes activated during the inflammatory process, resulting in the production of ... | 18,947,376 |
Hemostasis and ageing. | On March 19, 2008 a Symposium on Pathophysiology of Ageing and Age-Related Diseases was held in Palermo, Italy. The lecture of D. Mari on Hemostasis and ageing is summarized herein. Physiological ageing is associated with increased plasma levels of many proteins of blood coagulation together with fibrinolysis impairmen... | 18,947,391 |
Chlamydia trachomatis diversity viewed as a tissue-specific coevolutionary arms race. | The genomes of pathogens are thought to have evolved under selective pressure provided by the host in a coevolutionary arms race (the 'Red Queen's Hypothesis'). Traditionally, adaptation by pathogens is thought to rely not on whole chromosome dynamics but on gain/loss of specific genes, yielding differential abilities ... | 18,947,394 |
Comparing the xylose reductase/xylitol dehydrogenase and xylose isomerase pathways in arabinose and xylose fermenting Saccharomyces cerevisiae strains. | Ethanolic fermentation of lignocellulosic biomass is a sustainable option for the production of bioethanol. This process would greatly benefit from recombinant Saccharomyces cerevisiae strains also able to ferment, besides the hexose sugar fraction, the pentose sugars, arabinose and xylose. Different pathways can be in... | 18,947,407 |
Extending the spectrum of Ellis van Creveld syndrome: a large family with a mild mutation in the EVC gene. | Ellis-van Creveld (EvC) syndrome is characterized by short limbs, short ribs, postaxial polydactyly, dysplastic nails and teeth and is inherited in an autosomal recessive pattern. We report a family with complex septal cardiac defects, rhizomelic limb shortening, and polydactyly, without the typical lip, dental, and na... | 18,947,413 |
Replantation of multiple digits and hand amputations: four case reports. | This study reports four cases of hand avulsion at the proximal wrist level and multiple digits amputation were received in plastic and hand surgery unit during the year 2007-2008. All patients were male labors between 22-30 years old, and the amputation due to machine injuries. Successful replantation were achieved, a... | 18,947,423 |
Analysis of differential gene-regulatory responses to zinc in human intestinal and placental cell lines. | Transcriptomic studies are useful for elucidating molecular mechanisms through which changes in nutrient availability produce pleiotropic effects on whole-body and tissue physiology. To further the knowledge of gene-regulatory effects of Zn on tissues important for adult and fetal Zn nutrition, we analysed the response... | 18,947,441 |
Methicillin-resistant Staphylococcus aureus in people living and working in pig farms. | We compared the prevalence of human and animal methicillin-resistant Staphylococcus aureus (MRSA) at pig farms in The Netherlands, and related this to individual and farm-level characteristics. More than half of the farms investigated (28/50) had MRSA in pigs or stable dust and about one third (15/50) of person(s) were... | 18,947,444 |
Post-release evaluation of Eretmocerus hayati Zolnerowich and Rose in Australia. | Bemisia tabaci biotype B is a significant pest of agriculture world-wide. It was first detected in Australia in 1994. Assessments of the potential of parasitoids already present in Australia to control this pest indicated that two species of Eretmocerus and 11 species of Encarsia were present, but they did not exert su... | 18,947,454 |
Uni-centric localization of Castleman's disease treated with laparoscopic and traditional approach. Report of two cases. | Castleman's disease (CD) is a rare lymphoproliferative disorder. Clinically CD has been subdivided in two forms: uni-centric and multicentric. The uni-centric type is limited to a single anatomic lymph-node-bearing region. The present report describes two cases of uni-centric CD: the first was an abdominal localization... | 18,947,460 |
[Related factors in the development of anemia in preterm infants]. | To investigate the related perinatal factors in the development of anemia of prematurity by a case-control study. The medical data of 165 preterm infants admitted to the department of neonatology in Peking University Third Hospital from January 2005 to December 2006 were retrospectively reviewed. The infants were class... | 18,947,476 |
[Assessment of the young rat model of visceral hypersensitivity by measuring electrical discharge of external oblique]. | To study the value of measuring electrical discharge of external oblique in assessment of young rat model of visceral hypersensitivity. Eight-day-old neonatal Sprague-Dawley rats were randomly assigned to two groups: an experimental group and a control group (n=16 each). Rats in the experimental group were subjected to... | 18,947,489 |
Trends in influenza vaccination coverage rates in the United Kingdom over six seasons from 2001-2 to 2006-7. | In order to understand motivations and barriers to vaccination, and to identify people's intentions to get vaccinated for season 2007-8, influenza vaccination coverage was assessed in the United Kingdom (UK) from 2001 to 2007. Between 2001 and 2007 representative household surveys were performed by telephone interview ... | 18,947,523 |
National seasonal influenza vaccination survey in Europe, 2008. | A cross-sectional survey was undertaken with the European Union (EU) Member States and Norway and Iceland to describe seasonal influenza immunisation in the 2006-7 season, in particular to identify country-specific recommendations for risk groups, obtain vaccine uptake information and allow comparison with global recom... | 18,947,524 |
Evaluation of urinary and faecal continent stomas. | To evaluate the outcome and complications of urinary and faecal continent catheterizable stomas. Retrospective record review of all patients operated on in our institution within the last 6 years. Fifty-five children received 63 stomas. The mean age at operation was 9.2 years and the mean follow-up period was 2.8 years... | 18,947,542 |
Differences in embryogenesis of epispadias, exstrophy-epispadias complex and hypospadias. | Minor variants of a spectrum of anomalies are usually more common than the major variants. Penile epispadias is rare compared with the relatively more common exstrophy-epispadias complex, but it has been assumed that the former is simply a lesser form of the latter. This assumption is challenged and an alternative expl... | 18,947,553 |
Continent urinary diversion with a urachal remnant. | The Mitrofanoff procedure, first described in 1980, has been widely adopted for pediatric continent urinary diversion to increase patient independence and continence, decrease morbidity and infections, and preserve renal function. Although this principle employs the appendix primarily, numerous other tissue conduits ha... | 18,947,570 |
A case of bilateral prenatal testicular torsion: Ultrasonographic features, histopathological findings and management. | The aim of this study was to demonstrate the ultrasonographic features of prenatal bilateral torsion of the testis, and its histological correlation and management. A newborn presented at delivery with both testes enlarged, swollen and tender. Prenatal ultrasound (US) showed enlarged, hyperechoic testes. Colour Doppler... | 18,947,572 |
Surgical treatment of neuropathic urinary incontinence in 2005. When, what, and how? | We present our current opinions on the surgical treatment of urinary incontinence in children with spina bifida. The age of treatment, preferred treatment modalities and results are discussed. We emphasize the importance of initiating treatment for incontinence at an early age as well as the use of effective surgical t... | 18,947,575 |
Anterior urethral valve associated with posterior urethral valves. | The association of anterior urethral valve (AUV) with posterior urethral valve (PUV) is rare. A 7-month-old infant was presented at a district hospital with episodes of acute pyelonephritis. He was treated medically and a voiding cystourethrogram (VCUG) confirmed bilateral vesico-urethral reflux. The presence of concom... | 18,947,585 |
Conservative management of overactive bladder in children: evaluation of clinical and urodynamic results. | Overactive bladder in children may indicate serious anatomic as well as functional changes in both the lower and upper urinary tracts. In order to prevent such problems, these patients should be diagnosed quickly and treated appropriately. In this study, children with diurnal and nocturnal enuresis symptoms (without an... | 18,947,592 |
The effect of indwelling catheter on OH-proline in the urethral wound: an experimental study. | To investigate the effect of catheterization on urethral wound healing by measuring OH-proline. Eighteen male New Zealand albino rabbits were divided equally into three groups. In the control group, urethral tissue samples were taken from the ventral penile surface. In group II, the ventral penile surface was incised a... | 18,947,605 |
Testicular germ cell tumors in children: management and outcome in a series of 20 patients. | Testicular germ cell tumors occurring during childhood are extremely rare. This study reports the clinical presentation, pathological diagnosis, treatment methods and outcome in a series of 20 boys, aged between 3.5 months and 16 years (median: 1.5 years; 19 were prepubertal), who were treated between 1963 and 2003. Hi... | 18,947,609 |
Ureteropelvic junction obstruction unmasked after correction of vesicoureteral reflux using endoscopic treatment with Deflux. | A case of intermittent ureteropelvic junction obstruction unmasked after correction of vesicoureteral reflux using endoscopic treatment with Deflux is presented. The difficulty in diagnosis and making treatment decisions for patients with coexisting ureteropelvic junction obstruction and vesicoureteral reflux is discus... | 18,947,611 |
Collagen prolyl 4-hydroxylase is up-regulated in an acute bladder outlet obstruction. | Compliance is primarily related to extracellular matrix deposition, and prolyl 4-hydroxylase (P4Hs) plays a critical role in the synthesis of the matrix. To study the alteration of P4Hs, under the influence of variable hydrostatic pressure, a novel pressure device was used to expose human bladder smooth muscle cells (H... | 18,947,616 |
The role of renal resistive index measures in the diagnostic work up of congenital hydronephrosis. | To evaluate the role of renal resistive index (RI) measures in the diagnostic work up of congenital hydronephrosis. Seventeen neonatal pigs were randomized to either left-sided partial unilateral ureteral obstruction (n=12) or sham operation (n=5) at 2 weeks of age. Serial investigations including B-mode ultrasound, RI... | 18,947,629 |
Retroperitoneal laparoscopic nephrectomy in children: at last the gold standard? | We analyzed our experience with retroperitoneal laparoscopic nephrectomy giving special attention to the learning curve, morbidity, and feasibility in a teaching institution. Between 1996 and 2004, we performed 104 laparoscopic nephrectomies in 88 children. Only four were performed via the transperitoneal approach, the... | 18,947,636 |
Urinary urea excretion in idiopathic hypercalciuria of children. | In adults, it is well known that high protein intake may increase the risk of nephrolithiasis through increased urinary calcium excretion and other mechanisms. We aimed to assess the role of protein intake on urinary calcium excretion in children with idiopathic hypercalciuria (HC). The 24-h urinary urea excretion as a... | 18,947,649 |
Biofeedback therapy in the treatment of bladder overactivity, vesico-ureteral reflux and urinary tract infection. | Voiding disorders are commonly encountered in paediatric urology practice. Urinary incontinence often leads to the impairment of self-esteem but can also cause renal damage, when recurrent urinary tract infection (UTI) or vesico-ureteral reflux (VUR) exists. The aim of this study was to assess the efficacy of a biofeed... | 18,947,650 |
Significance of age-specific creatinine levels at presentation in posterior urethral valve patients. | Determination of prognostic factors is of great importance in decision making on therapies and informing parents about the probable outcome of disease. The present study aims to evaluate and assess the prognostic factors in posterior urethral valve (PUV) patients. The data of 68 patients treated between 1996 and 2004 w... | 18,947,654 |
An exceptional case of urogenital sinus associated with a scrotal pouch and duplicate urethra in a female child. | We report the case of an unusual genitourinary anomaly in a 5-year-old patient. The malformation consisted of a para-anal persistent urogenital sinus in a 46XX patient associated with a scrotum-like structure in the presumed clitoral location. A duplicate urethra arising from the anterior aspect of the bladder neck dra... | 18,947,664 |
Collecting duct carcinoma arising from multicystic dysplastic kidney disease. | Malignancy arising from a multicystic dysplastic kidney (MCDK) is rare. Most reports are of Wilms' tumor and clear-cell renal cell carcinoma arising from a previously unrecognized MCDK. To our knowledge, no reports have described collecting duct carcinoma arising from MCDK. | 18,947,667 |
Extensive skin bridging with glans epithelium replacement by penile shaft skin following newborn circumcision. | Extensive skin bridging with replacement of glans epithelium by shaft skin is an unusual complication of newborn circumcision not previously described. Patients with extensive skin bridges and replacement of at least 50% of glans epithelium with shaft skin underwent lysis of the bridges and excision of displaced skin. ... | 18,947,680 |
Vesicoureteric reflux and tumor necrosis factor-alpha gene polymorphism. | To determine the role of tumor necrosis factor-alpha (TNF-alpha) gene polymorphism in promoting renal scarring among patients with vesicoureteric reflux (VUR). This genetic variant involves a guanosine to adenine transition at position -308, and this single-base polymorphism is associated with increased transcription o... | 18,947,693 |
Ibuprofen-induced papillary necrosis causing bilateral ureteric obstruction. | Ibuprofen, a non-steroidal anti-inflammatory drug, is the mainstay in the management of pain and fever in children. In most children, ibuprofen is well tolerated and does not produce significant adverse effects. We report a case of acute papillary necrosis causing bilateral ureteric obstruction induced by ibuprofen. | 18,947,702 |
Treatment of vesicoureteral reflux in children using stabilized non-animal hyaluronic acid/dextranomer gel (NASHA/DX): a long-term observational study. | Vesicoureteral reflux (VUR) can be treated with open surgery, antibiotic therapy or endoscopic injection. A goal in children is to reduce the incidence of febrile urinary tract infections (UTIs). The present long-term observational study investigated outcomes and experiences of endoscopic treatment with stabilized non-... | 18,947,708 |
Can urodynamic studies be dispensed with in the initial urologic management of children with meningomyelocele? A study of 30 cases and review of the literature. | To identify whether a relationship exists between information gathered from voiding patterns, neurological status and radiological findings, and the actual dysfunction seen on cystometry in children with spina bifida. Thirty consecutive children with spina bifida underwent clinical evaluation, urinary tract imaging and... | 18,947,734 |
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