title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Reversal of the enantiomeric elution order of some aromatic amino acids using reversed-phase chromatographic supports coated with the teicoplanin chiral selector. | In this paper, two chiral stationary phases were prepared by coating the surface of both C8 and C18 high-performance liquid chromatography (HPLC) supports with the teicoplanin chiral selector. The hydrophobic C11 acyl side chain, attached to the D-glucosamine group of teicoplanin, served as anchor moiety for the immobi... | 18,970,428 |
Capillary electrophoretic system incorporating an UV/CL dual detector. | We developed a capillary electrophoretic system incorporating an ultra-violet absorption (UV)/chemiluminescence (CL) dual detector, taking advantage of the CL reaction of luminol-hydrogen peroxide and the batch-type CL detection cell. UV detection was carried out using the on-capillary method while CL detection was per... | 18,970,433 |
Evaluation of different sample extraction strategies for selenium determination in selenium-enriched plants (Alliumsativum and Brassicajuncea) and Se speciation by HPLC-ICP-MS. | Several sample extraction techniques have been evaluated in order to obtain highest selenium (Se) extraction efficiency in two types of selenium-enriched plants (Allium sativum and Brassica juncea). Three extracting solutions have been studied for this purpose: 0.1M HCl, 25mM ammonium acetate buffer (pH 5.6) and protea... | 18,970,462 |
Use of FTIR spectroscopy coupled with ATR for the determination of atmospheric compounds. | Attenuated total reflection Fourier transformed infrared spectroscopy (ATR-FTIR) can be successfully used for the quantitative determination of small amounts of pollutants like the organic fraction of aerosols. The relation between sample concentration and reflectance is described by the Kubelka-Munk equation and was f... | 18,970,463 |
Plastified poly(ethylene terephthalate) (PET)-toner microfluidic chip by direct-printing integrated with electrochemical detection for pharmaceutical analysis. | Rapid separation and determination of acetaminophen and its hydrolysate with end-channel electrochemical (EC) detection integrated on a plastified poly(ethylene terephthalate) (PET)-toner microchip capillary electrophoresis (CE) system was investigated. In this separation and detection system, a Pt ultramicroelectrode ... | 18,970,464 |
Determination of mono- and dichloroacetic acids in betaine media by liquid chromatography. | A simple and sensitive method has been developed for the analysis of residue amounts of chloroacetic acids in betaine samples based on derivatization by 1-naphthylamine (NA). The derivatized compounds are analyzed by reverse phase high performance liquid chromatography using methanol and water as mobile phase in the ra... | 18,970,478 |
Micro-columns packed with Chlorella vulgaris immobilised on silica gel for mercury speciation. | A method has been developed for mercury speciation in water by using columns packed with Chlorella vulgaris immobilised on silica gel. The method involves the retention of CH(3)Hg(+) and Hg(2+) in micro-columns prepared by packing immobilised algae in polypropylene tubes, followed by selective and sequential elution wi... | 18,970,490 |
Metabolic profiling using principal component analysis, discriminant partial least squares, and genetic algorithms. | The aim of this study was to evaluate evolutionary variable selection methods in improving the classification of (1)H nuclear magnetic resonance (NMR) metabonomic profiles, and to identify the metabolites that are responsible for the classification. Human plasma, urine, and saliva from a group of 150 healthy male and f... | 18,970,515 |
Trends in metal-binding and metalloprotein analysis. | This review describes recent tendencies for metal-binding and metalloprotein analysis, emphasizing metal quantification in proteins through X-ray, atomic absorption, mass spectrometric techniques, and others. Hyphenated techniques such as capillary electrophoresis-synchrotron radiation X-ray fluorescence (CE-SRXRF), la... | 18,970,524 |
Highly sensitive and selective spectrofluorimetric determination of tolnaftate through the formation of ternary inclusion complex of beta-naphthol/beta-cyclodextrin/anionic surfactant system. | An indirect spectrofluorimetric method with high sensitivity and selectivity was developed for the determination of antifungal drug: tolnaftate (TNF), depending on the supramolecular multi-recognition interaction among the anionic surfactant sodium laurylsulfate (SLS), beta-cyclodextrin (beta-CD) and beta-naphthol (ROH... | 18,970,541 |
Trace analysis of acids and bases by conductometric titration with multiparametric non-linear regression. | A chemometric method for analysis of conductometric titration data was introduced to extend its applicability to lower concentrations and more complex acid-base systems. Auxiliary pH measurements were made during the titration to assist the calculation of the distribution of protonable species on base of known or guess... | 18,970,555 |
Flow-injection turbidimetric determination of homatropine methylbromide in pharmaceutical formulations using silicotungstic acid as precipitant reagent. | A flow-injection turbidimetric procedure exploiting merging zones is proposed for determining homatropine methylbromide (HMB) in pharmaceutical preparations. The determination is based on the precipitation reaction of homatropine methylbromide with silicotungstic acid in acidic medium to form a precipitate, which was m... | 18,970,560 |
Amperometric determination of chloroguaiacol at submicromolar levels after on-line preconcentration with molecularly imprinted polymers. | In this study, a sorbent flow preconcentration system coupled to amperometric detector for the chloroguaiacol (4-chloro-2-methoxyphenol) determination at submicromolar levels is described. The satisfactory selectivity of the proposed method was attained by means of the use of a chloroguaiacol-imprinted polymer, whose t... | 18,970,563 |
Periodically interrupted amperometry at membrane coated electrodes: a simplified pulsed amperometry. | Amperometric detection combined with separation technique or with selective molecular recognition step can be very effective solving quantitative analytical tasks. When the amperometric working electrode surface needs cleaning or reactivation, pulsed amperometric technique can be the choice. Coating working electrodes ... | 18,970,566 |
Separation and preconcentration of U(VI) on XAD-4 modified with 8-hydroxy quinoline. | Amberlite XAD-4 adsorber resin was modified with 8-hydroxy quinoline (Oxine) by equilibrating with methanol solution of the reagent and the modified resin was used as a support material for the solid phase extraction and preconcentration of UO(2)(2+) from aqueous solution at pH between 4 and 5.5. Ten micrograms of uran... | 18,970,579 |
A validation protocol for the HPTLC standardization of herbal products: application to the determination of acteoside in leaves of Plantago palmata Hook. f.s. | Formal validation, that is the study of the analytical performances of a method, is recognized as the best safeguard against the generation and publication of data with low reliability. Although the topic of HPTLC validations has been largely investigated, there is still a need for a general validation method applicabl... | 18,970,583 |
Conductometric nitrate biosensor based on methyl viologen/Nafion/nitrate reductase interdigitated electrodes. | A highly sensitive, fast and stable conductometric enzyme biosensor for determination of nitrate in water is reported for the first time. The biosensor electrodes were modified by methyl viologen mediator mixed with nitrate reductase (NR) from Aspergillus niger by cross-linking with glutaraldehyde in the presence of bo... | 18,970,588 |
Determination of 6-mercaptopurine based on the fluorescence enhancement of Au nanoparticles. | A novel method for the determination of 6-mercaptopurine (6MP) has been developed based on fluorescence enhancement of Au nanoparticles (AuNPs). The fluorescent AuNPs with mean diameter of approximately 15 nm were synthesized in aqueous solution, exhibiting the stable maximum emission at 367 nm, under the excitation at... | 18,970,589 |
Fluorous ionic liquids as solvents for the liquid-liquid extraction of metal ions by macrocyclic polyethers. | The predominant mode of strontium ion transfer from aqueous nitrate media into a series of 1-fluoroalkyl-3-methylimidazolium bis[(trifluoromethylsulfonyl)]imides containing dicyclohexano-18-crown-6 (DCH18C6) is shown to shift from cation exchange to strontium nitrato-crown ether complex partitioning as the length of th... | 18,970,599 |
Development of a radiochemical separation for selenium with the aim of measuring its isotope 79 in low and intermediate nuclear wastes by ICP-MS. | Selenium (Se) 79 is a beta emitter produced from (235)U fission thus occurring as one of the fission products found in nuclear reactors. Due to its long half life (about 10(5) years), (79)Se is one of the radionuclides of interest for the performance of assessment studies of waste storage or disposal. Thus, the Nationa... | 18,970,605 |
Determination of metals, metalloids and non-volatile ions in airborne particulate matter by a new two-step sequential leaching procedure Part B: Validation on equivalent real samples. | Due to the lack of proper standard materials for airborne particulate matter collected on filters, a validation scheme was developed, which is here described, to the aim of testing the application of leaching procedures performing both ions and elemental determinations on real samples of airborne particulate matter col... | 18,970,608 |
Determination of intrinsic viscosity of poly(ethylene terephthalate) using infrared spectroscopy and multivariate calibration method. | A methodology was developed to determine the intrinsic viscosity of poly(ethylene terephthalate) (PET) using diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) and multivariate calibration (MVC) methods. Multivariate partial least squares calibration was applied to the spectra using mean centering and... | 18,970,616 |
Near-infrared spectroscopy (NIRS) with a fibre-optic probe for the prediction of the amino acid composition in animal feeds. | The amino acids alanine, aspartic acid, glutamic acid, glycine, phenylalanine, valine, lysine, proline, and tyrosine present in feeds with different textures (blocks, tablets, granules and flour (meal) and used in different stages of animal feeding regimes (lactation, growth, maintenance, etc.) were analysed using near... | 18,970,626 |
Determination of PAHs in airborne particles by accelerated solvent extraction and large-volume injection-gas chromatography-mass spectrometry. | A sensitive and automated method is presented for the determination of polycyclic aromatic hydrocarbons (PAHs) in airborne particulate matter. The procedure includes extraction of PM10-bound PAHs by accelerated solvent extraction (ASE) followed by gel permeation chromatography (GPC) clean-up, and large-volume programma... | 18,970,641 |
Optimization of a single-drop microextraction procedure for the determination of organophosphorus pesticides in water and fruit juice with gas chromatography-flame photometric detection. | A single-drop microextraction (SDME) procedure was developed for the analysis of organophosphorus pesticides (OPPs) in water and fruit juice by gas chromatography (GC) with flame photometric detection (GC-FPD). The significant parameters affecting the SDME performance such as selection of microextraction solvent, solve... | 18,970,647 |
Flow injection spectrophotometric determination of andrographolide from Andrographis paniculata. | A simple flow injection colourimetric procedure for determining andrographolide was proposed. It is based on the reaction between andrographolide with 3,5-dinitrobenzoic acid, resulting in an intense purplish red complex with a suitable absorption at 536nm. A standard or sample solution was injected into the 3,5-dinitr... | 18,970,655 |
Quantitative analysis of isoflavone aglycones in human serum by solid phase extraction and liquid chromatography-tandem mass spectrometry. | This paper describes a liquid chromatography-electrospray-tandem mass spectrometry (LC-ESI-MS/MS) for the qualitative and quantitative analysis of three isoflavone aglycones (glycitein, daidzein and genistein) in human serum. Positive ion mode was used for the detection of these compounds and selective reaction monitor... | 18,970,663 |
Determination of diethylhexyl phtalate in water by solid phase microextraction coupled to high performance liquid chromatography. | Difficulties detected in the determination of the diethylhexylphthalate (DEHP) at trace levels by gas chromatography-mass spectrometry (GC-MS) using SPME, due to its ubiquitous distribution in the environment has been overcome and a new method for the determination of DEHP in drinking water has been proposed. The metho... | 18,970,687 |
Comparison of chemical modifiers for selenium determination in soil aqua regia extracts by ZETAAS. | The effect of various chemical modifiers 0.5 g l(-1) Pd, 1% (w/v) Ni, 0.5 g l(-1) Pd+1% (w/v) Ni and 1.0 g l(-1) Pd on the measurement of selenium in soil aqua regia extracts, by ZETAAS, is described. Two Certified Reference Materials (CRMs) RTC-CRM 023-050 and RTC-CRM 025-050 were used for this study. Pyrolysis and at... | 18,970,691 |
Determination of soluble phosphates in water samples using ytterbium(III) and dynamic measurements of light scattering intensity at long wavelength. | A selective and fast method has been developed for the determination of phosphates by measuring the formation of ytterbium(III) phosphate through the variation of the light scattering intensity with time. The low solubility of this compound causes an efficient dispersion of the radiation at 490 nm, which is measured at... | 18,970,693 |
New preservation method for inorganic arsenic speciation in acid mine drainage samples. | A new preservation method has been proposed for the speciation of As(III) and As(V) in acid mine drainage (AMD) samples, characterised by low pH and high metallic content. Samples were taken from a polymetallic sulphides mining area in the province of Huelva (SW Spain), under exploitation until the 1960s for its Cu, Pb... | 18,970,701 |
Inductively coupled plasma-sector field mass spectrometry with a high-efficiency sample introduction system for the determination of Pu isotopes in settling particles at femtogram levels. | An analytical method for the determination of plutonium concentration and its isotope ratio ((240)Pu/(239)Pu) for settling particle samples by inductively coupled plasma mass spectrometry (ICP-MS) is presented. The generally used approach for Pu preconcentration by increasing the amount of samples is not applicable bec... | 18,970,710 |
Determination of methyl ester contents in biodiesel blends by FTIR-ATR and FTNIR spectroscopies. | Partial last square regression (PLS) and artificial neural network (ANN) combined to FTIR-ATR and FTNIR spectroscopies have been used to design calibration models for the determination of methyl ester content (%, w/w) in biodiesel blends (methyl ester+diesel). Methyl esters were obtained by the methanolysis of soybean,... | 18,970,715 |
Electrochemiluminescent behaviors of alkaloids and tris(2,2'-bipyridine) ruthenium in organically modified silicate film. | Electrogenerated chemiluminescences (ECLs) of alkaloids, such as berberine, trigonelline, allantoin and betaine, were studied in an aqueous alkaline buffer solution (pH 9.5), based on tris(2,2'-bipyridine)ruthenium(II) [Ru(bpy)(3)(2+)] immobilized in organically modified silicates (ORMOSILs) film on a glassy carbon ele... | 18,970,736 |
The chemiluminescence mechanism of 3,4-bis(3-indolyl)-1H-pyrrole-2,5-dione, and the characteristics of chemiluminescence developed in the reaction with CH(3)CNH(2)O(2)NaOH. | The chemiluminescence (CL) mechanism of 3,4-bis(3-indolyl)-1H-pyrrole-2,5-dione (IPD) was investigated using liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS) of the products formed after the IPD CL reaction. We found that IPD produced strong CL via the decomposition of dioxetane formed after ... | 18,970,740 |
Ion-exclusion/adsorption chromatography of dimethylsulfoxide and its derivatives for the evaluation to quality-test of TiO(2)-photocatalyst in water. | Ion-exclusion/adsorption chromatography of dimethylsulfoxide (DMSO) and its derivatives, i.e., methanesulfinic acid (MSI), methanesulfonic acid (MSA) and sulfuric acid (SA), was developed in order to clear the decomposition mechanism of DMSO on quality-test of TiO(2)-photocatalyst in water. The separation was achieved ... | 18,970,746 |
Ion-exclusion chromatography with the direct UV detection of non-absorbing inorganic cations using an anion-exchange conversion column in the iodide-form. | An ion-exclusion chromatographic method for the direct UV detection of non-absorbing inorganic cations such as sodium (Na(+)), ammonium (NH(4)(+)) and hydrazine (N(2)H(5)(+)) ions was developed by connecting an anion-exchange column in the I(-)-form after the separation column. For example, NH(4)(+) is converted to a U... | 18,970,747 |
Rapid determination of bromide in seawater samples by capillary ion chromatography using monolithic silica columns modified with cetyltrimethylammonium ion. | Monolithic silica capillary columns dynamically modified with quaternary ammonium ions were evaluated for the determination of bromide in seawater samples. A quaternary ammonium ion such as cetyltrimethylammonium ion was dynamically introduced onto monolithic silica surfaces. The first layer of the modifier was introdu... | 18,970,751 |
Simultaneous preconcentration of uranium(VI) and thorium(IV) from aqueous solutions using a chelating calix[4]arene anchored chloromethylated polystyrene solid phase. | A new chelating polymeric sorbent is developed using Merrifield chloromethylated resin anchored with calix[4]arene-o-vanillinsemicarbazone for simultaneous separation and solid phase extractive preconcentration of U(VI) and Th(IV). The "upper-rim" functionalized calix[4]arene-o-vanillinsemicarbazone was covalently link... | 18,970,761 |
Influence of different extraction methods on the yield and linalool content of the extracts of Eugenia uniflora L. | This work has been developed using a sylvestral fruit tree, native to the Brazilian forest, the Eugenia uniflora L., one of the Mirtaceae family. The main goal of the analytical study was focused on extraction methods themselves. The method development pointed to the Clevenger extraction as the best yield in relation t... | 18,970,765 |
Authentication of vegetable oils on the basis of their physico-chemical properties with the aid of chemometrics. | In food production, reliable analytical methods for confirmation of purity or degree of spoilage are required by growers, food quality assessors, processors, and consumers. Seven parameters of physico-chemical properties, such as acid number, colority, density, refractive index, moisture and volatility, saponification ... | 18,970,766 |
Investigation of the association behaviors between biliverdin and bovine serum albumin by fluorescence spectroscopy. | The interaction between biliverdin and bovine serum albumin (BSA) has been studied by steady fluorescence spectroscopy, synchronous fluorescence and resonance light scanning spectra. The binding of biliverdin to BSA quenches the tryptophan residue fluorescence and the results show that both static and dynamic quenching... | 18,970,778 |
Probing trace Pb(2+) using electrodeposited N,N'-(o-phenylene)-bis-benzenesulfonamide polymer as a novel selective ion capturing film. | A novel film modified electrode for the determination of trace lead was developed in this work. The modified electrode was prepared by the electropolymerization of N,N'-(o-phenylene)-bis-benzenesulfonamide (PBSA) as the ion capturing reagent to create the functional film. The modified electrode shows a high selectivity... | 18,970,788 |
Gold colloid-bienzyme conjugates for glucose detection utilizing surface-enhanced Raman scattering. | It is difficult to detect glucose by surface-enhanced Raman spectroscopy (SERS) due to the small normal Raman cross-section and the weak adsorption of glucose molecules on the surface of noble metal. A simple and fast method is proposed in this paper for the detection of glucose based on SERS signal of the enzyme react... | 18,970,804 |
A simple taste analyzing system design for visual and quantitative analysis of different tastes using multi-array chemical sensors and pattern recognition techniques. | In this paper, we describe design of a simple taste analyzing system using sensory system based on a multi-array chemical sensor (MACS) and personal digital assistant (PDA) for visual and quantitative analysis of different tastes using pattern recognition techniques. The sensory system is communicated with PDA, which h... | 18,970,806 |
Conversion of chromium(III) propionate to chromium(VI) by the Advanced Oxidation Process Pretreatment of a biomimetic complex for metal analysis. | The use of H(2)O(2) and UV irradiation to remove organic ligands in a chromium(III) complex for the subsequent chromium analysis is reported. The Advanced Oxidation Process (AOP) using a 5.5-W UV lamp, H(2)O(2) and Fe(2+)/Fe(3+) as catalyst (photo Fenton process) was found to give complete and quantitative Cr(III)-->... | 18,970,825 |
Identification and distribution of contamination sources in the Ebro river basin by chemometrics modelling coupled to geographical information systems. | Identification of the main contamination sources of heavy metals, organic compounds and other physicochemical parameters in Ebro river surface waters and description of their temporal and spatial distributions, are analyzed using chemometrics and geostatistical methods. Historical data available from the Confederación ... | 18,970,828 |
Occurrence of betablockers in effluents of wastewater treatment plants from the Lyon area (France) and risk assessment for the downstream rivers. | Five betablockers (oxprenolol, metoprolol, propranolol, bisoprolol, betaxolol) were analysed in effluents collected over a 3-month period from wastewater treatment plants (WTP) from the Lyon area in France. The analytical protocol consisted of solid phase extraction of the dissolved aqueous phase on HLB cartridges and ... | 18,970,833 |
Determination of total water content in inulin using the volumetric Karl Fischer titration. | A new sample preparation method for the water content determination of inulin by volumetric Karl Fischer (KF) titration was developed and compared to the usual method of introducing the sample directly in the methanol-based working medium, modified or not by formamide (1:3, v/v) in order to increase sample solubility. ... | 18,970,874 |
Determination of epichlorohydrin in water and sewage samples. | The simple, quick and effective methods for the analysis of epichlorohydrin (ECH) in water and sewage samples with the use of gas chromatography have been presented. From among all the methods developed, the procedures for monitoring drinking-water quality and the methods which allow the determination of epichlorohydri... | 18,970,879 |
Evaluation of two commercial capillary columns for the enantioselective gas chromatographic separation of organophosphorus pesticides. | The separation of the enantiomers of 13 organophosphorus pesticides (OPPs) has been investigated by gas chromatography (GC) with flame ionisation detection (FID) using two different commercially available chiral columns, Chirasil-Val (l-valine-tert-butylamide) and CP-Chirasil-Dex CB (heptakis (2,3,6-tri-O-metil)-beta-c... | 18,970,881 |
Kinetics of oil saponification by lead salts in ancient preparations of pharmaceutical lead plasters and painting lead mediums. | Lead soaps can be found in archaeological cosmetics as well as in oil paintings, as product of interactions of lead salts with oil. In this context, a better understanding of the formation of lead soaps allows a follow-up of the historical evolution of preparation recipes and provides new insights into conservation con... | 18,970,891 |
The relationship between dysphoria and proneness to hallucination and delusions among young adults. | Previous research suggests that measures of dysphoria relate to positive schizophrenic symptoms. These relationships have rarely been studied within the dimensionality of psychopathology framework. The present study examined the relationship between 3 distinct aspects of dysphoria (depression and state and trait anxiet... | 18,970,902 |
Clinical characteristics of trichotillomania with trichophagia. | Little is known about trichophagia in individuals with trichotillomania. Although studies have mentioned the behavior, no previous studies have examined clinical correlates of trichophagia. We examined the clinical correlates of trichophagia in 68 subjects with Diagnostic and Statistical Manual of Mental Disorders, Fou... | 18,970,906 |
Primary paratesticular neuroblastoma: a case report and review of literature. | Only 4 infants with primary paratesticular neuroblastoma have been previously described. To the author's knowledge, this case would be the first report of a child who is older than 1 year whose lesion is in his right hemiscrotum. After simple tumorectomy was performed; he was tumor free at 4 years of follow-up. Patient... | 18,970,922 |
Synchronous bilateral Wilm's tumor with complete radiographic response managed without surgical resection: a report from the National Wilm's Tumor Study 4. | We reviewed the long-term local tumor control in patients with bilateral Wilm's tumor (BWT) who received no definitive surgical therapy to one kidney after complete radiographic resolution after initial chemotherapy. National Wilm's Tumor Study 4 (NWTS-4) enrolled 3335 patients (pts) during the period August 1986 to Au... | 18,970,928 |
Unusual variants of congenital pouch colon with anorectal malformations. | Anorectal malformations are common worldwide. Several classifications were used to describe the different types, but in spite of this, there are rare variants. This report describes 2 unusual cases of congenital pouch colon and anorectal malformations. | 18,970,947 |
Endoscopic management of recurrent tracheoesophageal fistula with trichloroacetic acid chemocauterization: a preliminary report. | Open repair with a second thoracotomy is technically challenging and has a high risk of complications for the treatment of a recurrent tracheoesophageal fistula (RTEF). Therefore, less invasive endoscopic techniques have been developed. Here, we report on the chemocauterization with trichloroacetic acid (TCA) technique... | 18,970,956 |
The brachial artery-brachial vein fistula: expanding the possibilities for autogenous fistulae. | The National Kidney Foundation Dialysis Outcomes and Quality Initiative recommends autogenous access for new dialysis procedures. The patient requiring hemodialysis with inadequate superficial arm veins represents a formidable challenge to the surgeon. Our objective is to describe results with an alternative access pro... | 18,971,036 |
Polydeoxyribonucleotide (PDRN) restores blood flow in an experimental model of peripheral artery occlusive disease. | This study investigated whether polydeoxyribonucleotide (PDRN) may be efficacious in the treatment of peripheral artery occlusive diseases, which are a major cause of morbidity in Western countries and still lack standardized treatment. We investigated the effects of PDRN, a mixture of deoxyribonucleotides, in an exper... | 18,971,038 |
Successful treatment tailored to each splanchnic arterial lesion due to segmental arterial mediolysis (SAM): report of a case. | Segmental arterial mediolysis (SAM) is a rare condition characterized by splanchnic arterial catastrophe caused by mediolysis. We report a 59-year-old man with a ruptured splenic arterial aneurysm who was successfully treated by coil embolization. He underwent additional resection of large gastroepiploic and residual s... | 18,971,044 |
The spiral glenohumeral ligament: an open and arthroscopic anatomy study. | The purpose of this study was to visualize arthroscopically and to describe the micro- and macroscopic anatomy of the poorly known ligament of the anterior capsule of the glenohumeral joint: the so-called ligamentum glenohumerale spirale (spiral GHL). Twenty-two fresh shoulder joints were dissected, and the anatomy of ... | 18,971,058 |
Assessment and augmentation of symptomatic anteromedial or posterolateral bundle tears of the anterior cruciate ligament. | The anterior cruciate ligament (ACL) consists of 2 anatomic and functional bundles, the anteromedial (AM) and posterolateral (PL) bundle. Depending on the mechanism of injury, there are different injury patterns to the AM and PL bundles, demonstrating a wide spectrum of partial ACL tears. Clinical interest has recently... | 18,971,061 |
Assessing health and safety in early care and education programs: development of the CCHP health and safety checklist. | To assess health and safety in early care and education (ECE) programs, an objective, standardized instrument was developed based on the recommended national health and safety standards. The California Childcare Health Program Health and Safety Checklist was developed by conducting a literature review, identifying a go... | 18,971,083 |
[Urological emergencies at the Dakar university teaching hospital: epidemiological, clinical and therapeutic features]. | To present the epidemiological, clinical and therapeutic features of the urological emergencies in Senegal, West Africa. The authors conducted a 20 months retrospective study that analyzed the epidemiological, clinical and therapeutic features of all urological emergencies admitted to the urology department of the univ... | 18,971,107 |
[Using the intersitital cystitis new diagnostic criteria in daily practice: about 156 patients]. | To describe the characteristics of patients with interstitial cystitis and to determine what proportion of those patients met the European Society for the Study of interstitial cystitis/painful bladder syndrome 2005 (ESSIC IC/PBS) definition and how those who met the definition differed from those who did not. A total ... | 18,971,112 |
Cancer as an endocrine problem. | Many of the most common cancers that blight our societies are very rare in other large populations in the world; studies of migrants exclude a simple genetic explanation for these wide geographical variations and imply that environmental exposures are key determinants of the development of these cancers. The most heavi... | 18,971,117 |
Nutrition, metabolic factors and cancer risk. | Excess body weight (adiposity) and physical inactivity are increasingly being recognized as major nutritional risk factors for cancer, and especially for many of those cancer types that have increased incidence rates in affluent, industrialized parts of the world. In this review, an overview is presented of some key bi... | 18,971,118 |
Exogenous and endogenous hormones and breast cancer. | Exposure to higher levels of both exogenous and endogenous hormone is associated with breast cancer risk. Because of the association between breast cancer and HRT, only the minimal duration of HRT use is recommended for symptom control, and it is not recommended for chronic disease management. Current research issues i... | 18,971,119 |
Vitamin D and breast cancer risk. | In addition to its important role in the maintenance of the skeleton, there is mounting evidence that vitamin D has effects on other body systems, and that adequate supplies of vitamin D are likely to be required for optimal health. Vitamin D is obtained both from dietary sources and from cutaneous synthesis with expos... | 18,971,120 |
Evaluation and treatment of menorrhagia in an adolescent population. | Bleeding in adolescence is a common but, potentially, difficult condition to manage. Adolescents present with unique issues related to their age, involvement of family members, different differential diagnosis when compared to an older populations, and challenges associated with their evaluation and treatment. | 18,971,130 |
[Effects of ascorbic acid and citric acid on iron bioavailability in an in vitro digestion/ Caco-2 cell culture model]. | To study the effects of ascorbic acid and citric acid on iron bioavailability using an in vitro digestion/Caco-2 cell culture model and evaluate the validity of this cell model. This model combined in vitro digestion technique with Fe uptake by Caco-2 cells by utilizing an inserted ring attached to a dialysis membrane ... | 18,971,162 |
[Reactive astrocytes and nestin expression in adult rats following spinal cord compression injury]. | To observe the expressions of nestin and glial fibrillary acidic protein (GFAP) and their association with reactive astrocytes following spinal cord injury in adult rats. Adult rats with compression injury of the spinal cord were divided into 7 groups (n=6) and examined at 1, 3, and 5 days and at 1, 2, 4 and 8 weeks af... | 18,971,163 |
[Expression of FMNL2 and its relation to the metastatic potential of human colorectal cancer cells]. | To explore the association of FMNL2 expression with the metastatic potential of colorectal cancer cells. FMNL2 mRNA and protein expressions in 6 human colorectal cancer cell lines were detected by real-time RT-PCR and immunohistochemical method, respectively, and analyzed for their correlations to the in vitro invasive... | 18,971,169 |
[Post-transplant prophylaxis of the recurrence of lamivudine-resistant YMDD mutant hepatitis B virus in liver recipients]. | To evaluate the prophylactic efficacy of adefovir dipivoxil (ADV) for post-transplant recurrence of hepatitis B virus (HBV) with lamivudine-resistant YMDD mutation in liver recipients. From March 2004 to May 2006, 20 patients with chronic hepatitis B associated with YMDD mutant HBV prior to liver transplantation receiv... | 18,971,179 |
[Pharmacokinetics of nalmefene after a single or multiple intravenous doses in Chinese healthy volunteers]. | To investigate the pharmacokinetics of nalmefene after intravenous administration at a single or multiple doses in Chinese healthy volunteers. This open, randomized clinical trial involved 12 healthy volunteers, who received a single-dose (2 mg) nalmefene injection. Before and at different time points after the injecti... | 18,971,181 |
Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion. | In postischemic acute kidney injury (AKI) or acute renal failure, a dissipation of glomerular filtration pressure is associated with an altered renal vascular tone and reactivity, as well as a loss of vascular autoregulation. To test the hypothesis that renal nitric oxide (NO) generation reflects endothelial damage in ... | 18,971,208 |
Long-term control of choroidal neovascularisation secondary to angioid streaks treated with intravitreal bevacizumab (Avastin). | To evaluate the efficacy of intravitreal bevacizumab (IB) in the long-term control of subfoveal choroidal neovascularisation (CNV) associated with angioid streaks (AS). Patients with unilateral active CNV associated with AS were enrolled. Exclusion criteria were previous treatment for CNV and comorbidity. Postoperative... | 18,971,232 |
Correlation of visual recovery with presence of photoreceptor inner/outer segment junction in optical coherence images after epiretinal membrane surgery. | To investigate the relationship between the presence of the photoreceptor inner and outer segment (IS/OS) junction and visual acuity after epiretinal membrane (ERM) surgery. Seventy eyes of 70 consecutive patients who had undergone vitrectomy for idiopathic ERM were examined by optical coherence tomography before and 3... | 18,971,234 |
Effect of latanoprost and timolol on the histopathology of the human conjunctiva. | To investigate the effect of timolol and latanoprost on the extracellular matrix organisation, inflammatory infiltration, and expression of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the human conjunctiva. Conjunctival biopsies were obtained from the inferior fornix d... | 18,971,237 |
Knowledge-based expert systems and a proof-of-concept case study for multiple sequence alignment construction and analysis. | The traditional approach to bioinformatics analyses relies on independent task-specific services and applications, using different input and output formats, often idiosyncratic, and frequently not designed to inter-operate. In general, such analyses were performed by experts who manually verified the results obtained a... | 18,971,242 |
Physical activity interventions in the workplace: the rationale and future direction for workplace wellness. | The developing and developed worlds are both facing an obesity epidemic with their workers getting bigger, or to be more specific, fatter. As demonstrated elsewhere in this issue, the individual and societal health and economic costs of obesity and physical inactivity are enormous. There is thus a need for regional, na... | 18,971,246 |
Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts. | The P2X7 receptor (P2X7R) is an ATP-gated cationic channel expressed by hematopoietic, epithelial, and neuronal cells. Prolonged ATP exposure leads to the formation of a nonselective pore, which can result in cell death. We show that P2X7R is associated with detergent-resistant membranes (DRMs) in both transfected huma... | 18,971,257 |
The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion. | Kaposi's sarcoma (KS) associated herpesvirus (KSHV) is the etiological agent of KS. In vivo, KS is a tumor capable of spreading throughout the body, and pulmonary metastasis is observed clinically. In vitro, KSHV induces the invasiveness of endothelial cells. The KSHV open reading frame K15 is a KSHV-specific gene enco... | 18,971,265 |
Mechanism of NS2B-mediated activation of NS3pro in dengue virus: molecular dynamics simulations and bioassays. | The NS2B cofactor is critical for proteolytic activation of the flavivirus NS3 protease. To elucidate the mechanism involved in NS2B-mediated activation of NS3 protease, molecular dynamic simulation, principal component analysis, molecular docking, mutagenesis, and bioassay studies were carried out on both the dengue v... | 18,971,276 |
Genetic history of hepatitis C virus in East Asia. | The hepatitis C virus (HCV), which currently infects an estimated 3% of people worldwide, has been present in some human populations for several centuries, notably HCV genotypes 1 and 2 in West Africa and genotype 6 in Southeast Asia. Here we use newly developed methods of sequence analysis to conduct the first compreh... | 18,971,279 |
The novel micro-opioid receptor antagonist, [N-allyl-Dmt(1)]endomorphin-2, attenuates the enhancement of GABAergic neurotransmission by ethanol. | We investigated the effects of [N-allyl-Dmt(1)]endomorphin-2 (TL-319), a novel and highly potent micro-opioid receptor antagonist, on ethanol (EtOH)-induced enhancement of GABA(A) receptor-mediated synaptic activity in the hippocampus. Evoked and spontaneous inhibitory postsynaptic currents (eIPSCs and sIPSCs) were iso... | 18,971,291 |
Developmental sensitivity of hippocampal interneurons to ethanol: involvement of the hyperpolarization-activated current, Ih. | Ethanol (EtOH) has powerful effects on GABA(A) receptor-mediated neurotransmission, and we have previously shown that EtOH-induced enhancement of GABA(A) receptor-mediated synaptic transmission in the hippocampus is developmentally regulated. Because synaptic inhibition is determined in part by the firing properties of... | 18,971,298 |
Prokaryotic silencing (psi)RNAs in Pyrococcus furiosus. | In many prokaryotes, noncoding RNAs that arise from the clustered regularly interspaced short palindromic repeat (CRISPR) loci are now thought to mediate defense against viruses and other molecular invaders by an RNAi-like pathway. CRISPR loci contain multiple short regions of similarity to invader sequences separated ... | 18,971,321 |
Mechanism of thermal decomposition of carbamoyl phosphate and its stabilization by aspartate and ornithine transcarbamoylases. | Carbamoyl phosphate (CP) has a half-life for thermal decomposition of <2 s at 100 degrees C, yet this critical metabolic intermediate is found even in organisms that grow at 95-100 degrees C. We show here that the binding of CP to the enzymes aspartate and ornithine transcarbamoylase reduces the rate of thermal deco... | 18,971,327 |
Structure of ratcheted ribosomes with tRNAs in hybrid states. | During protein synthesis, tRNAs and mRNA move through the ribosome between aminoacyl (A), peptidyl (P), and exit (E) sites of the ribosome in a process called translocation. Translocation is accompanied by the displacement of the tRNAs on the large ribosomal subunit toward the hybrid A/P and P/E states and by a rotatio... | 18,971,332 |
Time to leave substantiation behind: findings from a national probability study. | Data from the National Survey of Child and Adolescent Well-being, a national probability study of children and families investigated for child maltreatment, were analyzed to answer the question: Do substantiated and unsubstantiated cases differ in rates of recidivism over 36 months? Recidivism was classified as (a) any... | 18,971,346 |
Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat. | Peroxisome proliferator-activated receptor-gamma (PPARgamma) agonism potently reduces circulating triglycerides (TG) in rodents and more modestly so in humans. This study aimed to quantify in vivo the relative contribution of hepatic VLDL-TG secretion and tissue-specific TG clearance to such action. Rats were fed an ob... | 18,971,352 |
Ciprofloxacin-resistant Salmonella enterica serovar typhi from Kuwait with novel mutations in gyrA and parC genes. | Blood isolates of Salmonella enterica serovar Typhi from two recently returned Bangladeshi patients in Kuwait were ciprofloxacin resistant, with ciprofloxacin MICs of 12 mg/liter for both isolates. Both isolates had three novel gyrA mutations (55-Leu-->Trp, 87-Asp-->Ala, and 106-Gln-->Arg) and three novel parC... | 18,971,360 |
Emergence and characterization of community-associated methicillin-resistant Staphyloccocus aureus infections in Denmark, 1999 to 2006. | The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) infections has changed worldwide. From being strictly nosocomial, MRSA is now frequently found as a community-associated (CA) pathogen. Denmark has been a low-prevalence country for MRSA since the mid-1970s but has in recent years experienced an inc... | 18,971,362 |
Chronic treatment with the dipeptidyl peptidase-4 inhibitor BI 1356 [(R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione] increases basal glucagon-like peptide-1 and improves glycemic control in diabetic rodent models. | Antidiabetic effects of dipeptidyl peptidase-4 (DPP-4) inhibitors are exerted by potentiation of the biological activity of incretin hormones like glucagon-like peptide (GLP)-1. BI 1356 [proposed trade name Ondero; (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purin... | 18,971,371 |
Improving gait in multiple sclerosis using robot-assisted, body weight supported treadmill training. | The majority of patients with multiple sclerosis (MS) develop progressive gait impairment, which can start early in the disease and worsen over a lifetime. A promising outpatient intervention to help improve gait function with potential for addressing this treatment gap is task-repetitive gait training. Body weight sup... | 18,971,381 |
The US health care system: Part 1: Our current system. | The US health care crisis is of great concern to American neurologists. The United States has the world's most expensive health care system yet one-sixth of Americans are uninsured. The cost and volume of procedures is expanding, while reimbursement for office visits is declining. Pharmaceutical costs, durable goods, a... | 18,971,443 |
Expression and regulation of IFNalpha/beta receptor in IFNbeta-treated patients with multiple sclerosis. | The cytokine interferon beta (IFNbeta) is successfully used in the treatment of multiple sclerosis (MS), although there is a high degree of variability in the response. A common mechanism involved in the modulation of responsiveness to cytokines is represented by regulation of their receptor expression through autocrin... | 18,971,450 |
Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice. | Many neuropsychiatric diseases are associated with cognitive rigidity linked to prefrontal dysfunction. For example, schizophrenia and Parkinson's disease are associated with performance deficits on the Wisconsin Card Sorting Test, which evaluates attentional set shifting. Although the genetic underpinnings of these di... | 18,971,455 |
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