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Neural substrates for reversing stimulus-outcome and stimulus-response associations.
Adaptive goal-directed actions require the ability to quickly relearn behaviors in a changing environment, yet how the brain supports this ability is barely understood. Using functional magnetic resonance imaging and a novel reversal learning paradigm, the present study examined the neural mechanisms associated with re...
18,971,462
Online contributions of auditory feedback to neural activity in avian song control circuitry.
Birdsong, like human speech, relies critically on auditory feedback to provide information about the quality of vocalizations. Although the importance of auditory feedback to vocal learning is well established, whether and how feedback signals influence vocal premotor circuitry has remained obscure. Previous studies in...
18,971,480
Characteristics associated with longer breastfeeding duration: an analysis of a peer counseling support program.
Breastfeeding peer counseling support programs for low-income women have been implemented across the United States. Data from one such program were used to examine participant and program characteristics, of those enrolled prenatally (n = 2168) or postnatally (n = 2899), and to determine how these characteristics affec...
18,971,503
Effects of the Y chromosome on cardiovascular risk factors in Japanese men.
Excess cardiovascular risk in men compared with women has been suggested to be partly explained by effects of the Y chromosome. However, inconsistent results have been reported on the Y chromosome's genetic influence on blood pressure and lipid levels. The purpose of the present study was to settle the question whether...
18,971,546
Risk factors for cesarean delivery in preterm, term and post-term patients undergoing induction of labor with an unfavorable cervix.
To identify risk factors for cesarean delivery in patients with an unfavorable cervix undergoing an indicated induction of labor. This is a secondary analysis of combined data from three prospective randomized trials comparing cervical ripening methods in singleton pregnancies with an unfavorable cervix seeking to iden...
18,971,583
Indocyanine green angiography in experimental choroidal circulatory disturbance.
To determine how choroidal venous congestion alters the indocyanine green angiograms (ICGA) of monkeys. Two vortex veins in each eye of 5 Japanese macaque monkeys were sutured and cauterized at their exit. ICGA and fluorescein angiography (FA) were performed immediately after the occlusions. The FA and ICGA findings we...
18,971,589
[Evaluation of multiplex PCR assay using dual priming oligonucleotide system for detection mutation in the Duchenne muscular dystrophy gene].
Exon deletions of Duchenne muscular dystrophy (DMD) gene account for most of the alterations found in DMD and Becker muscular dystrophy (BMD). This study was to evaluate the usefulness of dual priming oligonucleotide multiplex PCR (DPO PCR) in detection of exon deletions of DMD gene. Thirty-seven DMD or BMD patients wh...
18,971,620
Brain energetics (thought needs food).
Almost 15 years after its initial proposal, the astrocyte-neuron lactate shuttle hypothesis still occupies the center stage in research on brain energetics. Recent developments have provided further evidence for its validity and have extended its application to different areas of neuroscience. Description of cell-speci...
18,971,641
The role of Title VII funding in academic general pediatrics fellowships and leadership.
Since 1979, the Health Resources and Services Administration, Bureau of Health Professionals Title VII, Section 747 (Title VII) programs have been critical to both fellowship and leadership training in academic general pediatrics. Title VII-funded faculty development programs and targeted contract funding have played a...
18,971,667
Osteoporosis: how long should we treat?
Bisphosphonates are the most commonly used treatment for osteoporosis. The pharmacology of bisphosphonates suggests the possibility of discontinuing treatment for a period, and patients frequently ask about this. In an attempt to help answer these questions, this review will consider recent data relevant to continuing ...
18,971,678
Nasal reconstruction with local flaps: a simple algorithm for management of small defects.
After studying this article, the participant should: 1. Be familiar with subunits of the nose. 2. Understand various flaps used in nasal reconstruction. 3. Be able to choose a flap for the defect depending on its location, size, shape and orientation. Management of small defects in nasal reconstruction can be quite cha...
18,971,686
Avoiding denervation of rectus abdominis in DIEP flap harvest II: an intraoperative assessment of the nerves to rectus.
The deep inferior epigastric artery perforator (DIEP) flap aims to reduce donor-site morbidity by minimizing rectus muscle damage; however, damage to motor nerves during perforator dissection may denervate rectus muscle. Although cadaveric research has demonstrated that individual nerves do not arise from single spinal...
18,971,714
Motility differences in free colon and free jejunum flaps for reconstruction of the cervical esophagus.
Free colon and jejunal flaps have been described as reliable and safe conduits for pharyngoesophageal reconstruction. Compared with free colon flaps, free jejunum flaps have a smaller diameter and intrinsic peristaltic movement, both of which are considered possible causes of dysphagia. In this investigation, the autho...
18,971,724
Diastasis recti: clinical anatomy.
Enduring diastasis repair is one of the yardsticks by which a successful abdominoplasty is measured, because the presence and size of diastasis recti are thought to be reliable indicators of abdominal wall laxity and protrusion. The author's study of the "normal" anatomy of diastasis challenges these concepts about dia...
18,971,741
Return to work after spinal cord injury: is it related to wheelchair capacity at discharge from clinical rehabilitation?
To describe the number of people with spinal cord injury who returned to work (RTW) 1 yr after discharge from inpatient rehabilitation and to investigate whether RTW can be predicted from wheelchair capacity at discharge from inpatient rehabilitation, after correction for confounders. Prospective cohort study in which ...
18,971,766
Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer.
Tumor budding along the advancing front of colorectal adenocarcinoma is an early event in the metastatic process. A reproducible, prognostic budding scoring system based on outcomes in early stage colorectal cancer has not been established. One hundred twenty-eight T3N0M0 colorectal carcinoma patients with known outcom...
18,971,777
[Thrombo-embolic risks and bevacizumab: data from the literature and recommendations for the use of anticoagulants and antiaggregants].
Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. The use of bevacizumab has shown survival benefit in variety of cancers. However, a specific toxicity profile has been observed with bevacizumab such as hypertension, proteinuria, gastrointestinal perforation and arterial thrombosis. Non-s...
18,971,808
[Early-stage NSCLC. The renaissance of radiotherapy in early-stage non-small cell lung cancer].
Surgery is the current standard treatment of early-stage non-small cell lung cancer (stage I and II tumors). Contrary to adjuvant chemotherapy, which was recently demonstrated to decrease systemic tumor recurrences as well as increasing overall survival, postoperative radiotherapy did not benefit from an actualized eva...
18,971,830
[Satisfaction and compliance of ocular hypertensive and glaucoma patients topically treated with a combination therapy].
To evaluate satisfaction and compliance in glaucoma and ocular hypertensive patients receiving a fixed combination treatment. After instilling a fixed combination, patients were asked to fill out a questionnaire about their satisfaction and compliance at baseline and 15 days after the onset of new therapy. 1693 glaucom...
18,971,850
Behavioral and psychological symptoms and the progression of dementia of the Alzheimer type in nursing home residents.
Behavioral and psychological symptoms are common in the course of dementia of the Alzheimer's type (DAT). Some behavioral and psychological symptoms may be predictors of the progression of dementia and cognitive impairment in DAT. However, studies on this topic face serious methodological problems. The aim of our study...
18,971,872
Recurrent respiratory infections: why not talking about it any more?
Recurrent respiratory infections (RRIs) are a common and benign condition affecting about 6% of schoolchildren. Only mild, likely postinfective, modifications of the immune system have been proven, and parents should be reassured that the condition is self-limited. Nevertheless, if not correctly diagnosed, children may...
18,971,902
Markers of acute coronary syndrome in emergency room.
Acute coronary syndromes (ACS) encompasses a spectrum of coronary heart diseases, ranging in severity from unstable angina to ST-elevation myocardial infarction (STEMI). Early diagnosis and risk stratification are needed in order to address correctly hospitalization and treatment. Although the diagnosis of STEMI in the...
18,971,915
Prevalence of selected risk behaviors and chronic diseases--Behavioral Risk Factor Surveillance System (BRFSS), 39 steps communities, United States, 2005.
Behavioral risk factors (e.g., tobacco use, poor diet, and physical inactivity) can lead to chronic diseases. In 2005, of the 10 leading causes of death in the United States, seven (heart disease, cancer, stroke, chronic lower respiratory diseases, diabetes, Alzheimer's disease, and kidney disease) were attributable to...
18,971,922
Hormonal regulation of hepatic drug-metabolizing enzyme activity during adolescence.
Activities of drug-metabolizing enzymes (DMEs) are known to change throughout the course of physical and sexual maturation, with the greatest variability noted during infancy and adolescence. The mechanisms responsible for developmental regulation of DME are currently unknown. However, the hormonal changes associated w...
18,971,926
Brain metabolism dictates the polarity of astrocyte control over arterioles.
Calcium signalling in astrocytes couples changes in neural activity to alterations in cerebral blood flow by eliciting vasoconstriction or vasodilation of arterioles. However, the mechanism for how these opposite astrocyte influences provide appropriate changes in vessel tone within an environment that has dynamic meta...
18,971,930
Safety and pharmacokinetics of motesanib in combination with gemcitabine for the treatment of patients with solid tumours.
The aim of this open-label phase 1b study was to assess the safety and pharmacokinetics of motesanib in combination with gemcitabine in patients with advanced solid tumours. Eligible patients with histologically or cytologically documented solid tumours or lymphoma were enroled in three sequential, dose-escalating coho...
18,971,935
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.
The DNA damage response (DDR) has an essential function in maintaining genomic stability. Ataxia telangiectasia-mutated (ATM)-checkpoint kinase 2 (Chk2) and ATM- and Rad3-related (ATR)-Chk1, triggered, respectively, by DNA double-strand breaks and blocked replication forks, are two major DDRs processing structurally co...
18,971,944
Another role of proline: stabilization interactions in proteins and protein complexes concerning proline and tryptophane.
Proline-tryptophan complexes derived from experimental structures are investigated by quantum chemical procedures known to properly describe the London dispersion energy. We study two geometrical arrangements: the "L-shaped", stabilized by an H-bond, and the "stacked-like", where the two residues are in parallel orient...
18,972,023
The effect of methylprednisolone on treatment in rats with induced sepsis.
In this study, an appropriate sepsis model was created in rats. Additionally, the effects of steroid treatments on survival, in connection with antibiotic treatment, were investigated. The sepsis model performed via intraperitoneal injection of 3 ml/kg fecal suspension was determined as the most appropriate model for o...
18,972,065
Behavioral indices in medical care outcome: the working alliance, adherence, and related factors.
The working alliance has been shown to be a consistent predictor of patient outcome and satisfaction in psychotherapy. This study examines the role of the working alliance and related behavioral indices in predicting medical outcome. Cognitive and emotional dimensions of the physician-patient relationship were examined...
18,972,089
[Principles of the developmental process and implementation of guidelines. An update].
Guidelines are important tools to improve knowledge management, processes and outcomes in health care. Their function is to assist professionals and patients decisions about appropriate and effective practice, especially in those areas of health care where considerable variation or potential for improvement exists. The...
18,972,093
Inhaled milrinone attenuates experimental acute lung injury.
To test whether inhalation of the phosphodiesterase 3 inhibitor milrinone may attenuate experimental acute lung injury (ALI). In rats, ALI was induced by infusion of oleic acid (OA). After 30 min, milrinone was inhaled either as single dose, or repeatedly in 30 min intervals. In mice, ALI was induced by intratracheal i...
18,972,099
[Glucocorticoids in rheumatology].
Glucocorticoids (GC) are effective drugs which are often used in rheumatology. However, they have a considerable potential for frequent and sometimes serious side effects that restrict their use. Their mechanisms of action are either receptor dependent (specific) or independent (unspecific) on the genomic as well as th...
18,972,122
Imaging of hereditary hemorrhagic telangiectasia.
This pictorial review is based on our experience of the follow-up of 120 patients at our multidisciplinary center for hereditary hemorrhagic telangiectasia (HHT). Rendu-Osler-Weber disease or HHT is a multiorgan autosomal dominant disorder with high penetrance, characterized by epistaxis, mucocutaneous telangiectasis, ...
18,972,161
An evaluation of four phylogenetic markers in Nostoc: implications for cyanobacterial phylogenetic studies at the intrageneric level.
The success of some phylogenetic markers in cyanobacteria owes to the design of cyanobacteria-specific primers, but a few studies have directly investigated the evolution "behavior" of the loci. In this study, we performed a case study in Nostoc to evaluate rpoC1, hetR, rbcLX, and 16S rRNA-tRNA(Ile)-tRNA(Ala)-23S rRNA ...
18,972,163
Comparison of surgically resected polypoid lesions of the gallbladder to their pre-operative ultrasound characteristics.
Polypoid lesions of the gallbladder (PLG) have been a common finding on ultrasound examinations of the abdomen and are more prevalent since our use of equipment incorporating pulse shaping increased bandwidth, and enhanced phase use for image reconstruction began in 1996. Our study correlates the pre-operative ultrason...
18,972,168
Characteristics of mammography facility locations and stage of breast cancer at diagnosis in Chicago.
In the United States, despite substantial investment in public health initiatives to promote early detection of breast cancer through screening mammography, the proportion of female breast cancers that have advanced beyond the localized stage by the time of diagnosis remains high. Our objective in this exploratory stud...
18,972,211
Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature.
Adrenal cystic lesions are uncommon and we analyzed clinical and pathologic features of 25 such cases from a single institute over 23 years. There were 16 pseudocysts, eight endothelial cysts, and one epithelial cyst. Seven of eight endothelial cysts were confirmed to be lymphangiomatous by D2-40 immunostaining. We sug...
18,972,224
Novel factor-loaded polyphosphazene matrices: potential for driving angiogenesis.
Currently employed bone tissue engineered scaffolds often lack the potential for vascularization, which may be enhanced through the incorporation of and regulated release of angiogenic factors. For this reason, the objective here was to fabricate and characterize protein-loaded amino acid ester polyphosphazene (Pphos)-...
18,972,247
The issue of consent in research that administers drugs of addiction to addicted persons.
In addiction, impaired control over drug use raises questions about the capacity of addicted persons to consent to participate in research studies in which they are given their drug of addiction. We review the case for doing such research, and the arguments that addiction does, and does not, prevent addicted persons fr...
18,972,263
Biomedical research and the commercialization agenda: a review of main considerations for neuroscience.
This article reviews a range of issues associated with the commercialization of biomedical research and speculates on how these issues might apply to the neuroscience context. Drawing on existing studies of the impact of research commercialization activities on various areas of biotechnology research, the authors explo...
18,972,268
Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers.
Smoking-related respiratory diseases are a major cause of morbidity and mortality. However, the relationship between smoking and respiratory disease has not been well-studied among ethnic minorities in general and among women in particular. The objective of this cross-sectional study was to evaluate the risk of airflow...
18,972,275
The properties and functions of virus encoded microRNA, siRNA, and other small noncoding RNAs.
microRNAs (miRNAs) represent a class of noncoding RNA species, believed to be regulating gene expression by binding to complementary sites in the 3'UTRs of target mRNAs. They play important regulatory roles in various metabolic pathways in most eukaryotes. The recent discovery of virus encoded miRNAs suggests that viru...
18,972,284
Autobiographical memory in long-term survivors of severe traumatic brain injury.
The aim of this study was to examine the ability of persons who had sustained a severe traumatic brain injury (TBI) at least 6 years previously to recall memories associated with famous names. Each of 19 persons with TBI was matched with a healthy control of the same age, gender, and occupational-educational background...
18,972,310
Outcome measures in physiotherapy management of patients with stroke: a survey into self-reported use, and barriers to and facilitators for use.
OBJECTIVE. To investigate physiotherapists' self-reported use of outcome measures as recommended in the Dutch Clinical Practice Guideline on Physiotherapy Management of Patients with Stroke (CPGPS) and to assess perceived barriers to and facilitators for the use of outcome measures in everyday practice. A 41-item surve...
18,972,323
Improved delayed enhanced myocardial imaging with T2-Prep inversion recovery magnetization preparation.
To develop a magnetization preparation method that improves the differentiation of enhancing subendocardial infarction (MI) from ventricular blood for myocardial delayed-enhancement (DE) magnetic resonance imaging (MRI). T2Prep-IR is a magnetization preparation pulse that consists of a T2 preparation (T2Prep) followed ...
18,972,338
Measurement of liver stiffness with two imaging techniques: magnetic resonance elastography and ultrasound elastometry.
To cross-validate the magnetic resonance elastography (MRE) technique with a clinical device, based on an ultrasound elastometry system called Fibroscan. Ten healthy subjects underwent an MRE and a Fibroscan test. The MRE technique used a round pneumatic driver at 60 Hz to generate shear waves inside the liver. An elas...
18,972,339
Consideration of physiological response in numerical models of temperature during MRI of the human head.
To examine the thermal effects of the physiological response to heating during exposure to radiofrequency (RF) electromagnetic fields in magnetic resonance imaging (MRI) with a head-specific volume coil. Numerical methods were used to calculate the temperature elevation in MRI of the human head within volume coils from...
18,972,342
Cross-correlation delay to quantify myocardial dyssynchrony from phase contrast magnetic resonance (PCMR) velocity data.
To apply cross-correlation delay (XCD) analysis to myocardial phase contrast magnetic resonance (PCMR) tissue velocity data and to compare XCD to three established "time-to-peak" dyssynchrony parameters. Myocardial tissue velocity was acquired using PCMR in 10 healthy volunteers (negative controls) and 10 heart failure...
18,972,349
Assessment of histone acetylation levels in relation to cell cycle phase.
Histone acetylation affects chromatin structural organization, thus regulating gene expression and DNA-related cellular events. Levels of histone acetylation are tightly modulated in normal cells and frequently altered in tumors. Consequently, histone deacetylase inhibitors are currently being tested in clinical trials...
18,972,367
Diphenyl diselenide protects against hematological and immunological alterations induced by mercury in mice.
Mercury is a heavy metal that can cause a variety of toxic effects on the organism, such as hematological and immunological alterations. In the present investigation, deleterious effects of mercury-intoxication in mice and a possible protective effect of diphenyl diselenide (PhSe)(2) were studied. Male adult Swiss albi...
18,972,395
Chronic alcohol consumption augments loss of sialic acid residues and alters erythrocyte membrane charge in type II diabetic patients.
In this study, the effects of alcohol consumption on erythrocyte membrane properties in type 2 diabetic patients were investigated. Therefore, we measured total and lipid-bound sialic acid (LSA) levels, sialidase activities, and erythrocyte membrane negative charge. Three groups, including control group (n = 20), alcoh...
18,972,396
Sputum eosinophil apoptotic rate is positively correlated to exhaled nitric oxide in children.
Exhaled nitric oxide (FE(NO)), a potential biomarker for asthma, is positively correlated with eosinophilic airway inflammation. Eosinophil apoptotic rate (AR) may be increased by NO but the relationship between eosinophil AR and NO has not been studied in vivo. This study tested the hypothesis that eosinophil AR will ...
18,972,415
Survival after surgical resection of pulmonary metastases and second primary squamous cell lung carcinomas in head and neck cancer.
Patients with head and neck squamous cell carcinoma (HNSCC) are at risk for developing both pulmonary metastasis and second primary lung cancer (SPLC). The objective of this study was to determine survival characteristics of patients with pulmonary lesions after curative treatment for HNSCC. Lung resection or biopsy sp...
18,972,427
Analysis of 49 cases of flap compromise in 1310 free flaps for head and neck reconstruction.
The purpose of this study was to analyze the causes of flap compromise and failure in head and neck free flap reconstruction. We retrospectively reviewed 1310 free flap reconstructions for head and neck defects performed between July 1995 and June 2006. Forty-nine cases of flap compromise due to vascular obstruction (3...
18,972,428
The stem cell niche of human livers: symmetry between development and regeneration.
Human livers contain two pluripotent progenitors: hepatic stem cells and hepatoblasts. The hepatic stem cells uniquely express the combination of epithelial cell adhesion molecule (EpCAM), neural cell adhesion molecule (NCAM), cytokeratin (CK) 19, albumin +/-, and are negative for alpha-fetoprotein (AFP). They are prec...
18,972,441
Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury.
Oxidative injury to hepatocytes occurs as a result of hepatitis C virus (HCV) infection and replication. Modulation of host cell antioxidant enzymes such as heme oxygenase-1 (HO-1) may be useful therapeutically to minimize cellular injury, reduce viral replication, and attenuate liver disease. In this report, we evalua...
18,972,446
Oxidation leading to reduction: redox-induced electron transfer (RIET).
Complex electron transfer reactions have been characterized whereby in addition to electron transfer, subsequent electrochemical, chemical and even in some cases biological consequences occur. These include a secondary electron transfer that leads to a major rearrangement of the electronic structure, such that an initi...
18,972,460
A novel Ni(4) complex exhibiting microsecond quantum tunneling of the magnetization.
A highly asymmetric Ni(II) cluster [Ni(4)(OH)(OMe)(3)(Hphpz)(4)(MeOH)(3)](MeOH) (1) (H(2)phpz=3-methyl-5-(2-hydroxyphenyl)pyrazole) has been prepared and its structure determined by means of single-crystal X-ray diffraction by using synchrotron radiation. Variable-temperature bulk-magnetization measurements show that t...
18,972,463
Cyclic peptides from Oldenlandia affinis DC. Molecular and biological properties.
A new isolation procedure for Kalata polypeptides from the tropical plant Oldenlandia affinis DC is described. Fractions were screened by thin-layer chromatography, and Van Urk positive fractions were tested for oxytocic activity in estrogenized rat uteri. By using this procedure, we were able to isolate and characteri...
18,972,522
Evaluation of the utility of neutral-loss-dependent MS3 strategies in large-scale phosphorylation analysis.
Phosphopeptide identification and site determination are major challenges in biomedical MS. Both are affected by frequent and often overwhelming losses of phosphoric acid in ion trap CID fragmentation spectra. These losses are thought to translate into reduced intensities of sequence informative ions and a general decl...
18,972,524
Modelling the sulfoxygenation activity of vanadate-dependent peroxidases.
Vanadate-dependent peroxidases contain, in their active center, vanadate covalently attached to histidine in an overall trigonal-bipyramidal array. We describe here the synthesis and characterization of optically active amino alcohols and their vanadium(V) complexes, and we show that the structural models of the active...
18,972,532
Proteome approaches combined with Fourier transform infrared spectroscopy revealed a distinctive biofilm physiology in Bordetella pertussis.
Proteome analysis was combined with whole-cell metabolic fingerprinting to gain insight into the physiology of mature biofilm in Bordetella pertussis, the agent responsible for whooping cough. Recent reports indicate that B. pertussis adopts a sessile biofilm as a strategy to persistently colonize the human host. Howev...
18,972,542
Postmortem changes in the neuroanatomical characteristics of the primate brain: hippocampal formation.
Comparative studies of the structural organization of the brain are fundamental to our understanding of human brain function. However, whereas brains of experimental animals are fixed by perfusion of a fixative through the vasculature, human or ape brains are fixed by immersion after varying postmortem intervals. Altho...
18,972,553
Inhibition of Kupffer cell-mediated early proinflammatory response with carbon monoxide in transplant-induced hepatic ischemia/reperfusion injury in rats.
Proinflammatory responses play critical roles in hepatic ischemia/reperfusion (I/R) injury associating with liver transplantation (LTx), and carbon monoxide (CO) can effectively down-regulate them. Using wild-type (WT) to enhanced green fluorescent protein (EGFP)-transgenic rat LTx with 18-hour cold preservation in Uni...
18,972,563
Degeneration of acetabular articular cartilage to bipolar hemiarthroplasty.
This study examined the rate of degeneration of acetabular cartilage by the bipolar head according to time, and also which clinical factors are related to the degeneration of acetabular cartilage. Among 192 patients (226 hip joints) who received bipolar hemiarthroplasty from August 1996 to August 2002, 61 patients (65 ...
18,972,591
Severe paradoxical reaction requiring tracheostomy in a human immunodeficiency virus (HIV)-negative patient with cervical lymph node tuberculosis.
During drug treatment of tuberculous lymphadenitis, paradoxical response (PR) may occasionally occur. Continued treatment or lymph node aspiration improves PR without severe sequelae. However, we report a case of severe PR in a patient with cervical lymph node tuberculosis causing airway obstruction due to retropharyng...
18,972,608
Laparoscopic enucleation of a nonfunctioning neuroendocrine tumor of the pancreas.
Laparoscopic approaches are increasingly used in pancreatic surgery. In the treatment of neuroendocrine tumors (NETs) of the pancreas, enucleation is one of the recommended surgery. Although many clinical experiences have reported the safety and efficacy of laparoscopic enucleation of functioning NETs, such as insulino...
18,972,611
Nerve plexus invasion in pancreatic cancer: spread patterns on histopathologic and embryological analyses.
Although extrapancreatic nerve plexus (PLX) invasion is an important prognostic factor in pancreatic carcinoma, the spreading patterns of carcinoma via PLX have not been carefully explored because of the complex anatomical structures around the pancreas. Fifty-eight patients underwent pancreaticoduodenectomy for carcin...
18,972,625
Cardiogenic shock complicating myocardial infarction and outcome following percutaneous coronary intervention.
Cardiogenic shock is the commonest cause of death in acute myocardial infarction (AMI). Although the syndrome of cardiogenic shock complicating AMI is common to all, the spectrum of underlying pathology is broad. While thrombolysis can be attempted with inotropic support or augmentation of blood pressure with an intra-...
18,972,627
Changes in nutritive value of fish, Channa punctatus after chronic exposure to zinc.
The present investigation was undertaken to assess the effects of sublethal concentrations of zinc (0.1 and 0.2 mgl(-1)) on the nutritional value of fish Channa punctatus after exposure for 135 days. The parameters studied were, levels of total proteins, glycogen, total lipids, cholesterol and vitamins (A and D) in the...
18,972,681
Histopathological alterations of Nile tilapia, Oreochromis niloticus in acute and subchronic alachlor exposure.
Histopathological alterations in Nile tilapia, Oreochromis niloticus, aged 3 months and subjected to acute and subchronic alachlor exposure were studied by light microscopy LC50 values of alachlor for 24 hr 48 hr, 72 hr and 96 hr were 963.6, 563, 448, and 381.9 microg l(-1), respectively and the maximum acceptable toxi...
18,972,686
Study of bio-physico-chemical parameters of Mothronwala swamp, Dehradun (Uttarakhand).
Aquatic biodiversity is one of the most essential characteristics of the aquatic ecosystem formaintaining its stability and a means of coping with any environmental change. The entire stretch of the Mothronwala swamp has rich riparian vegetation for providing conducive environment for the growth of aquatic organisms. T...
18,972,696
Infant mortality statistics from the 2005 period linked birth/infant death data set.
This report presents 2005 period infant mortality statistics from the linked birth/infant death data file by a variety of maternal and infant characteristics. The linked file differs from the mortality file, which is based entirely on death certificate data. Descriptive tabulations of data are presented and interpreted...
18,972,721
U.S. decennial life tables for 1999-2001, United States life tables.
This report presents period life tables for the United States based on age-specific death rates for the period 1999-2001. These tables are the most recent in a 100-year series of decennial life tables for the United States. This report presents complete life tables by age, race (white and black), and sex. Also presente...
18,972,722
[Effects of electroacupuncture at points "Weibingfang" on EGF and EGFR mRNA expressions in rats with lesion of gastric mucosa].
To probe the mechanism of electroacupuncture at points "Weibingfang" in treatment of acute gastric mucosal lesion. Forty Wistar rats of sanitary degree were randomly divided into 4 groups, normal group, model group, sham-model group and Weibingfang group, 10 rats in each group. The acute gastric mucosal lesion model wa...
18,972,736
[A hypothesis about component model of substances of channels and collaterals].
The theory of channels and collaterals is a very important "substance" prop for the basic theories of TCM. After component model of substances of channels and collaterals is raised, according to the principle, structure and function are dialectical unity, the author finds in deeply research on a great number of complet...
18,972,738
Gene-environment interaction and the metabolic syndrome.
The metabolic syndrome, which has been shown to affect as many as 20% of the general adult US population, is generally described as a cluster of cardiovascular risks factors, most notably obesity, type 2 diabetes or resistance to insulin-stimulated glucose uptake (insulin resistance), dyslipidaemia and hypertension. Al...
18,972,748
Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections.
Like most human diseases, infectious diseases are effected by complex genetic traits and multiple, interactive environmental and inherent host factors. By linking specific genotypes to disease susceptibility phenotypes we can identify the genetic basis for inter-individual differences in disease susceptibility as well ...
18,972,751
Effect of additive metals, Sn, Ga, and In in Ag-Pd-Au-Cu alloys on initial bond strength of 4-META adhesive cement to these alloys.
The purpose of this study was to investigate the effects of three additives, Sn, Ga, and In, as well as the main constituents, Pd and Cu, of Ag-Pd-Au-Cu alloys on the initial bond strength of 4-META adhesive cement to these alloys. The Ag-Pd-Au-Cu alloys consisted of 20%, 30% or 40% Pd, and 10%, 15% or 20% Cu, 20% Au, ...
18,972,784
Chemical constituents and pharmacological properties of Radix Inulae.
Radix Inulae is used as a gastric and antibacterial agent in traditional Chinese and Tibetan medicines. Most of its chemical constituents have been identified and include a series of sesquiterpenes with various carbon skeletons such as: eudesmanolide, elemanolide, germacranolide, sesquicaranolide, guaianolide and humul...
18,972,829
Histone deacetylase inhibitors from the rhizomes of Zingiber zerumbet.
Histone acetylation and deacetylation play fundamental roles in the modulation of chromatin topology and the regulation of gene transcription. Histone deacetylase (HDAC) inhibitors that inhibit proliferation and induce differentiation and/or apoptosis of tumor cells in culture and in animal models have been identified....
18,972,844
Management of infants and young children with fever without source.
There is considerable variation in the clinical management of infants and children with FWS. Community pediatricians generally do not follow clinical practice guidelines that are taught and used at academic training institutions. These guidelines are presented in Sidebar 1 (see page 677) and Sidebar 2. In general, the ...
18,972,849
Effectiveness of intravenous bisphosphonate in treatment of giant cell tumor: a case report and review of the literature.
Giant cell tumor is a benign locally aggressive tumor. The standard treatment is en bloc resection followed by major reconstructive surgery, or extended curettage conjunction with bone grafting or the use of bone cement implantations. Surgical treatment of giant cell tumor at the sacrum is associated with high morbidit...
18,972,907
[Voiding symptoms as presentation of an intravesical foreign body].
The presence of intravesical foreign bodies is exceptional; it is not a common emergency. Most foreign bodies have a sexual-erotic origin, although we cannot forget others such as elements left by the surgeon in the surgical field. We performed a bibliographic review on the topic. We performed a PubMed (MEDLINE) electr...
18,972,912
[Nonspecific sexual cord testicular tumor. Case report].
We report one case of gonadal stromal testicular tumor and perform a bibliographic review. We present the case of a 42 year-old male patient consulting for a painless right testicular mass. Orchiectomy was performed and the patient underwent follow-up. Nonspecific sexual cord tumors are extremely rare, with slow growin...
18,972,920
The racial geography of child welfare: toward a new research paradigm.
This article examines the community-level impact of concentrated child welfare agency involvement in African American neighborhoods. Based on interviews of 25 African American women in a Chicago neighborhood, the study found that residents were aware of intense agency involvement in their neighborhood and identified pr...
18,972,935
Addressing the disproportionate representation of children of color: a collaborative community approach.
The state of Indiana recommended a committee be formed to address the disproportional representation of black youth in out-of-home placements. In response, the Indiana Disproportionality Committee (IDC) was established. This article presents the development, objectives and future of the IDC. One of the objectives, rese...
18,972,942
Two years into the storm over pricing to and collecting from the uninsured--a hospital valuation expert examines the risk/return dynamics and asks: would fair pricing and fair medical debt repayment plans increase yields to hospitals and simultaneously mitigate these controversies?
As the controversies over 501(c)(3) "charitable" hospitals' pricing, collections, and charity care practices that emerged in the winter and spring of 2003 continue unabated--now involving government officials from city councils and county boards to state attorneys general and Congress as well as numerous class action l...
18,972,978
Financial effects of an influenza pandemic on US hospitals.
We estimate the financial effects of an influenza pandemic on US hospitals, including the cost of deferring elective admissions and the cost of uncompensated care for uninsured patients. Using US pandemic planning assumptions and national data on health care costs and revenues, a 1918-like pandemic would cause US hospi...
18,972,986
Leasing vs. owning a medical office: an analytical model.
Physicians often face a major financial dilemma: To lease or own their medical office. This article takes a set of typical assumptions for a real estate market and analyzes the capital costs, cash flow, and investment implications of the option of leasing a medical office versus owning a similar property. The paper ana...
18,972,995
The impact of HMO and hospital competition on hospital costs.
This study examines the impact of HMO penetration and competition on health system performance, as measured by hospital cost per adjusted admissions. The study population consisted of acute-care hospitals in the United States. The findings of this study suggest that there is no relationship between HMO competition and ...
18,973,002
[Effects of Forskolin on proliferation cell-cycle distribution and activation of the murine T lymphocytes in vitro].
To investigate the effects of Forskolin on activation, proliferation, and cell-cycle distribution of murine CD3+ T lymphocytes, and study the mechanisms of its immunosuppressive effect. Singel cell suspensions were prepared from murine lymph nodes. Fluorescence conjugated monoclonal antibodies and flow cytometry were u...
18,973,017
[Study on self-microemulsifying drug delivery system of Jiaotai Pill active components].
To develop self-microemulsifying drug delivery system (SMEDDS) of Jiaotai Pill active components and its quality control method. The solubility of berberine hydrochloride in different auxiliary-materials were investigated, and the self-microemulsion formula was optimized by studying the self-microemulsifying efficiency...
18,973,026
[A new method to optimize the performance of JPEG2000-based PACS images' storage, transmission and display].
In connection with the efficiency problem of narrow-band PACS medical images transmission and display and following the DICOM 3.0 standard and JPEG2000 code stream properties of progressing transmission and free access, this paper presents a new parallel processing method of the images transmission and display. This me...
18,973,030
[Liquid gastric-emptying measurement using an electrical bio-impedance method].
This paper introduces a 4-electrode gastric-emptying measurement system using an electrical bio-impedance method by which gastric-emptying experiments of 24 healthy volunteers have been carried out. The test results show that the base impedance is stable, the average GET/2 is 8.78 +/- 1.76 min. The new system provides ...
18,973,033
[A method of controlling the X-ray generator with PLC technique].
This text probes into the usage of PLC controller which controls the X-ray generator's basic parameters.
18,973,039
[Development and applications of the extracorporeal control point module on multi-mode medical images].
This paper introduces a display module which can be used on multi-mode medical images. The module has a small size and can be easily used for point-selecting puncture diagnosis and treatment, and registration for image fusion control points.
18,973,042
Severe head injury: clinicians' awareness of the literature.
1. To determine the awareness of the literature concerning therapeutic manoeuvres in severe closed head injury (CHI) among Canadian critical care clinicians and neurosurgeons, 2. To identify factors that affect utilization of these manoeuvres, and 3. To compare reported appropriateness and frequency of use with #1 and ...
18,973,063
Antioxidant enzyme activity and malondialdehyde concentration in the plasma and erythrocytes of patients with urticaria induced by nonsteroidal anti-inflammatory drugs.
It has been suggested that oxidative stress is a crucial event in some forms of urticaria. To evaluate the blood oxidant/antioxidant profile of patients suffering from urticaria induced by nonsteroidal anti-inflammatory drugs (NSAIDs). We measured the activity of the antioxidant enzymes copper-zinc superoxide dismutase...
18,973,101