title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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A population-based study of referral, diagnostic and treatment patterns for childhood acute lymphocytic leukemia. | In order to make decisions about cancer control programs, information is needed on the current management of cancer as actually practiced in the United States. A study to address this issue for acute lymphocytic leukemia in children (age 15 years and under) has been performed. The 101 patients represent all reported in... | 267,429 | [
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The non-operative management of splenic trauma. | Non-operative management of splenic trauma is not a widely accepted method of treatment. During the period 1964 to 1976, 39 children were treated in the Adelaide Children's Hospital for splenic trauma. Twenty-four were managed without operation, while 15 were treated by splenectomy. Recently, splenic scan has helped in... | 267,459 | [
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Surgical repair of a large incomplete cleft sternum. | Congenital deformities of the chest are not uncommon, are frequently symptomatic, and are readily correctable. This applies particularly to malfusion of the manubrium and upper sternum, which results in a bony deficiency together with divarication of the sternomastoid muscles and the sternoclavicular joints. Such defec... | 267,470 | [
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The role of the mandible in mouse palatal development revisited. | Growth changes associated with formation of the secondary palate were studied in H-Velaz mouse embryos by morphometric measurement of medial sagittal sections of the heads between days 13 and 15 of embryonic development. Horizontalization of the palatine processes depends primarily on the length of the mandible and is ... | 267,520 | [
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[New developments in depot inotophoresis of copper compounds]. | By means of two methods of the depot ionophoresis using an exterior voltage source and the galvanic pin element, polyvalent bactericidal compounds can be transported from a depot of copper calcium hydroxide into all arms of the apical delta. The method of working and long-term effects are described. | 267,567 | [
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[The image of the temporomandibular joint in the panoramic radiographs]. | Of the general panoramic radiographs those with an intraoral focus (magnifying panoramic radiography) are not suitable to represent the temporo-mandibular joint. In contrast, panoramic tomograms represent the temporo-mandibular joint better, but they cannot be recommended unreservedly for the exact evaluation of this r... | 267,579 | [
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The child and the adolescent: new rights for an "old" minority. | The use of the learning model is a necessary prerequisite for rendering dental care to the child or adolescent. The awareness of the emotional needs of the child and adolescent and the ability of the doctor to handle them is a requirement for an individual to treat these persons. The treatment plan and methods of treat... | 267,607 | [
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Juvenile periodontitis (periodontosis). | Juvenile periodontitis, characterized by early age of onset, rapid rate of periodontal tissue destruction and selective tooth involvement in the absence of commensurate aetiological factors, is recognized as a distinct clinical entity. The present paper describes the clinical findings and some immunological characteris... | 267,621 | [
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Dental education in Sénégal. | At the present time Senegal has two types of dental education: a full university training for dentists and a training programme for operating dental auxiliaries. The teaching objectives of the Institute of Dentistry and Stomatology were defined in such a way that these two grades work together in a public health team t... | 267,625 | [
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The laboratory surveillance of influenza epidemics in the United Kingdom 1968-1976. | The extensive laboratory investigations of respiratory disease in the U.K. over many years have demonstrated the frequency with which influenza viruses, both A and B, are found each winter. Only rarely are none isolated. These findings correlate well with other indicators of influenza such as increases in sickness bene... | 267,671 | [
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Sail flap excision for the iguana neck deformity. | A method of recontouring the lax submental tissues of the sagging neck is discussed. | 267,703 | [
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Chemotactic defect in Wegener's granulomatosis. | Chemotaxis of the polymorphonuclear (PMN) leukocytes from nine Wegener's granulomatosis patients was examined in vitro. All the patients except one showed remarkable decrease in their chemotactic activity: This might be caused by abnormality in the PMN leukocytes themselves. It was confirmed that there was no increase ... | 267,711 | [
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The manpower survey of oral surgery in 1974. Part 1 of two parts. 1. Introduction and some general characteristics of oral surgeons. | Questionnaires requesting much data about oral surgeons and their practice of the specialty were mailed to the members of the American Society of Oral Surgeons. A total of 2,251 usable questionnaires were returned. The methods used in the survey and to summarize the data have been described and some general characteris... | 267,746 | [
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Fatal mediastinitis after a dental infection. | The pertinent features of life-threatening complications of dental infections have been briefly reviewed with particular emphasis on the alterations of the clinical features of these conditions induced by antibiotic therapy. The clinician who deals with dental infections must exercise a high index of suspicion to consi... | 267,754 | [
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Metastatic thyroid carcinoma of the mandible mimicking an arteriovenous malformation. | A case of thyroid carcinoma metastatic to the mandible is presented. Particular attention has been called to its extremely vascular nature and a recommendation has been made that all lesions of such suspected vascularity should be preoperatively studied by angiography in an effort to provide insight into the nature of ... | 267,757 | [
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Effect of chlorhexidine on the hamster cheek pouch. Microcirculation and penetration studies. | The application of chlorhexidine gluconate on the intact cheek pouch of hamsters led to an immediate increase of flow velocity determined in venules beneath the epithelium. The application of [14C]chlorhexidine on the intact cheek pouch led to accumulation of labeled material in the liver and kidneys. Both findings ind... | 267,765 | [
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[Acute lymphoblastic leukemia and lymphoblastic lymphoma. Two names for one disease (author's transl)]. | Of 14 non-T-cell malignant non-Hodgkin lymphomas (mNHL) 5/14 presented with leukemic transformation of the bone marrow; in three more cases bone marrow involvement developed during an observation period of 60--200weeks. In 2/14 cases mNHL terminated the first continuous and complete remission of acute lymphoblastic leu... | 267,804 | [
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Tetracycline-induced extrinsic discoloration of the dentition. | Tetracycline, a broad-spectrum antibiotic, is known to cause intrinsic discoloration of the dentition. A case is being presented of extrinsic discoloration of the teeth associated with the use of this drug. This is believed to be the first such reported case in the literature. Possible mechanisms of how tetracycline ma... | 267,884 | [
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Primary localized amyloidosis of the palate. | A case of amyloid tumor of the palate is reported in a 10-year-old girl. The past history, the detailed general clinical and laboratory examinations, and biopsy specimens collected from the rectal mucosa, gingiva, tongue, and skin excluded other forms of localizations of amyloidosis. The isolated amyloid tumor is an ex... | 267,888 | [
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A rare presentation of splenic rupture. | Traumatic rupture of the spleen is a well known problem, complicating many types of abdominal injury. In contrast, a spontaneous rupture is a rare occurrence, mainly associated with a large spleen resulting from infections, the most common in this country being infectious mononucleosis. It is also a rare complication o... | 267,912 | [
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Nerve growth factor in mouse serum and saliva: role of the submandibular gland. | The concept that the salivary gland of the mouse is an endocrine organ for nerve growth factor (NGF) has been reexamined. Serum concentrations of the protein have been measured by radioimmunoassay in male and female mice and in mice from which the submandibular glands were removed. In spite of the fact that the submand... | 267,927 | [
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4,4'-Bis (1-anilinonaphthalene 8-sulfonate) (bis-ANS): a new probe of the active site of myosin. | The interaction of myosin subfragment-1 (S-1) with 4,4'-bis(1-anilinonaphthalene 8-sulfonate) (bis-ANS) has been studied by monitoring the fluorescence of the latter when the two components form a complex. Because ATP and ATP analogs partially displace complexed bis-ANS it has also been possible to study interactions o... | 267,928 | [
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Regulation by estrogen of the vitellogenin gene. | The vitellogenin gene is inactive in the liver of male Xenopus laevis, unless exogenous estrogen is administered. We have previously shown that conventional doses of estradiol-17beta result in the appearance of new hepatic messenger RNAs, some of which are encoded for vitellogenin. We now report that much higher doses ... | 267,932 | [
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Cerebrospinal fluid cytomorphology identification of benign cells originating in the central nervous system. | The chief cellular consituents of CSF are the "free cells" of the pia-arachnoid, ependyma, and choroid. These cells are of diverse types, but have their mesenchymal origin in common. Usually they offer no difficulty in identification since they are predominantly histiocytic. However, these "free cells" may be morpholog... | 268,120 | [
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Cytology at the end of pregnancy: significance of determinations of the eosinophilic and karyopyknotic indices. | The clinical usefulness of the cytologic findings "pre-term," "at term" and "post-term" are discussed briefly. For this investigation, the eosinophilic and pyknotic indices were obtained by counting one hundred cells in each of four microscopic fields. A separation function was calculated using the eosinophilic and pyk... | 268,124 | [
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Primary gastric lymphoplasmacytoid malignant lymphoma (gastric plasmacytoma): an endoscopic cytologic diagnosis. | A case of primary gastric plasmacytoma in which diagnosis was made preoperatively by an endoscopic technique is presented. Exfoliative cytology using a brush under direct visual control enabled the case to be classified as lymphoplasmacytoid malignant lymphoma. Data which favor the diagnosis of plasmacytoma are: 1) pla... | 268,130 | [
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[Impulse-cytophotometric determination of DNA content in blood cells in patients with leukemia]. | The method of impulse cytophotometry was applied for determination of DNA content of blood cells in patients with various types of leukaemia. It was found that at the time of improvement in acute leukaemia the proportion of cells in the non-proliferative stage increases. In chronic leukaemias the improvement was associ... | 268,133 | [
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The treatment of malignant pericardial effusion in carcinoma of the breast. | In three patients with metastatic carcinoma of the breast, control of a malignant pericardial effusion was achieved with a single pericardiocentesis followed by intensive systemic combination chemotherapy. No patient required reaspiration or any other form of local treatment. A trial of this conservative initial approa... | 268,175 | [
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A new index for the intensity of natural selection. | A new index for the intensity of natural selection is proposed, based upon the double exponential model for fitness functions. This index is defined as a variance and is such that a value of zero indicates no selection while a value of one indicates quite strong selection. The use of the index is demonstrated using pub... | 268,316 | [
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0.2469561,
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Duration of the electromyographic silent period following the jaw-jerk reflex in human subjects. | During voluntary jaw clenching, a sharp tap to the menton of the mandible resulted in a transitory silent period (pause) in the electromyographic activity of the masseter and anterior temporalis muscles. Factors that could influence the duration of the silent period were studied, including direction and magnitude of th... | 268,344 | [
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0.126... |
Lack of effect of excess glucocorticoid hormone on the rate of dentin deposition in rats. | A study was undertaken to determine the effect on the rate of deposition of dentin when high levels of adrenal glucocorticoid hormone are administered to rats. The results indicate that in the hypercorticoid rat, despite an increased eruption rate and a reduced width of incisor wall, no alteration occurs in the rate of... | 268,346 | [
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0.1580595,
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0.0834867,
0.383494,
0.05415463,
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Enamel biopsy results of children receiving fluoride tablets. | This study measured the fluoride in tooth enamel of 338 schoolchildren after daily use of acidulated phosphate-fluoride (APF) tablets, and investigated the relationship between observed amounts of enamel fluoride and incidence of caries. Randomly selected study groups received under supervision either one placebo table... | 268,377 | [
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0.243... |
Platelet-cancer cell interaction in metastasis formation: a possible therapeutic approcach to metastasis prophylaxis. | The mechanism of the early stage of metastasis formation by sticky blood-born cancer cells is discussed. Abnormal platelet aggregation to circulating and lodged cancer cells, as well as alterations of blood coagulation and fibrinolysis play an important role. The reducing effect of several platelet aggregation inhibito... | 268,396 | [
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Effects of the simultaneous administration of diethylstilbestrol and prednisolone on serum enzymes in Duchenne's muscular dystrophy. | The effects of diethylstilbestrol (DES) and prednisolone (Pr), administered alone or in combination, on the serum enzyme activities in Duchenne's muscular dystrophy (DMD) have been evaluated. When DES and Pr were given simultaneously to four boys with DMD, the mean creatine phosphokinase and lactate dehydrogenase level... | 268,398 | [
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0.3587619,
0.1041403,
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-... |
The cost of providing restorative dentistry in an alternative delivery mode. | This study is based on the Forsyth Dental School experiment, where it was shown that dental hygienists can be trained to perform restorative dental functions which are now the exclusive responsibility of dentists. The focus of the Forsyth study was to determine the length of training time required and to measure the qu... | 268,436 | [
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0.2... |
Paget's sarcoma in Tasmania. | Six proven cases of Paget's sarcoma occurred in Tasmania in the decade 1965 to 1974. The incidence was 0-16 cases per 100,000 population per year. The sex ratio was two male: one female. The average age was 61-2 years. All cases occurred in the pelvis or adjacent femur. Average time of survival after onset of symptoms ... | 268,486 | [
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0.2... |
Vitamin E and periodontitis in the rat. | This investigation was designed to study the effect of vitamin E on the course of periodontitis in thirty-six adult male albino rats. The rats were divided into three groups of twelve and placed on test diets which consisted of pelleted feed that either was deficient in, or contained adequate and high amounts of, vitam... | 268,572 | [
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0.08269726,
0.037821... |
Effectiveness of root canal irrigation. | When root canals are being enlarged, repeated irrigation is mandatory. Under the conditions of this study, the most significant factor in obtaining maximum results in root canal irrigation is the diameter of the canals. The removal of debris seems to be a function of canal diameter rather than the type of solution used... | 268,582 | [
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0.1310947,... |
A DNA fragment containing the origin of replication of the Escherichia coli chromosome. | A 38 kilobase pair region of the Escherichia coli K12 chromosome containing the replication origin has been physically mapped with restriction endonucleases EcoRI and HindIII. Replication starts within or very near a 1.3 kilobase pair HindIII fragment in the middle of this region and proceeds outward in both directions... | 268,621 | [
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Glycophorin and the concanavalin A receptor of human erythrocytes: their receptor function in lipid bilayers. | Two integral glycoproteins from the human erythrocyte have been studied after their incorporation into lipid bilayer systems. Glycophorin (which is the M/N blood group determinant) and the concanavalin A receptor were isolated and purified prior to incorporation into model membranes by dialytic removal of detergent fro... | 268,624 | [
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Tumor promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture. | Clones of Friend erythroleukemia cells, characterized by the presence of 40-70% benzidine-positive cells synthesizing hemoglobin in the absence of inducing drugs, were treated with several phorbol diesters with a known range of tumor-promoting activity on mouse skin. Good correlation was found between the reported tumo... | 268,640 | [
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Fatty liver induced in Zucker "fatty" (ff) rats by a semisynthetic diet rich in sucrose. | A new fatty liver model is described in which heredity plays a major role. A marked fatty liver develops when the homozygous mutant Zucker rat (ff or "fatty") is fed a semisynthetic diet enriched in sucrose. Lean littermates do not develop fatty liver on this experimental diet. Even old ff rats do not develop fatty liv... | 268,652 | [
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Nonlinear analysis of cat retinal ganglion cells in the frequency domain. | We have analyzed the responses of cat retinal ganglion cells to luminosity gratings that are modulated in time by a sum of sinusoids. A judicious choice of the component temporal frequencies permits a separation of the linear and second-order nonlinear components. Y cell responses show harmonic generation and intermodu... | 268,656 | [
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0.07285... |
A longitudinal study on the effect of unilateral extraction of primary molars. | The effect of unilateral extraction of the first or second primary molar on space conditions, need for orthodontic treatment, and eruption stage of permanent canines and second molars has been studied longitudinally in two groups. In Group 1 the first primary molar had been extracted early in 13 cases in the maxilla an... | 268,677 | [
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Intra-examiner reliability of epidemiologic registrations of malocclusion. | Intra-examiner consistency in the recording of single traits of malocclusion according to a previously described method was assessed by duplicate registrations on study models of 292 children. The level of agreement was expressed by the consistency ratio and the phi coefficient. A high level of consistency was obtained... | 268,920 | [
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Haemodynamic effects of pindolol in hypertensive patients. | Five men and five women, mean age 48 years, with hypertension in stages I or II of the WHO classification, were given preoral treatment with pindolol. The pindolol treatment lead a significant decrease in the systolic and diastolic blood pressure, at rest and during work both after 2 months and after 16 months treatmen... | 268,933 | [
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... |
Once a day treatment of hypertension. | Two studies are presented on the possibility of treating hypertension with pindolol once daily. In the first one, patients already treated with multiple doses of pindolol, propranolol or alprenolol were shifted to single dose regime with pindolol, given in the morning. In most cases an adequate blood pressure control c... | 268,934 | [
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[Forensic dentistry as an important part of legal medicine]. | Forensic dentistry is divided into two main subjects: 1. Dental jurisprudence and ethics and 2. Dental criminology. Dental jurisprudence and ethics include the legal duties of the dentist. They concern foremost the contractual relations between him and the patient and the duties which result from his actual dental acti... | 269,063 | [
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0.3... |
[Antimicrobial properties of cements with and without copper content]. | Copper-containing cements seem to inhibit bacterial growth better than copper-free materials. Twenty-four hours after insertion, a statistically significant difference is noted. The initial bactericidal effect of copper-free cements declines considerably as compared to copper-containing cements. The results obtained la... | 269,081 | [
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0.21472... |
The young child's response to repeated dental procedures. | Children's responses to dental procedures which were repeated over a series of six visits were studied. Response to a mirror and explorer examination at the beginning of each visit deteriorated initially and then improved over the last three visits. Responses to the four injections were increasingly negative. The respo... | 269,152 | [
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Electromyographic analysis of the "baccinator mechanism" in human beings. | Electromyography of the muscles of the "buccinator mechanism" was undertaken, utilizing indwelling fine-wire electrodes. Electromyograms were made of 14 subjects with normal occlusion during various oral activities. Several activities elicited simultaneous contraction of all muscles. Simultaneous activity represents a ... | 269,159 | [
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Late elongation of the cranial base. | A single logistic curve was fitted to serial data for three cranial base lengths (S-N, Ba-N, and Ba-S) in 33 boys and 26 girls. Elongation during pubescence plus adolescence is greater in boys than girls for each length. The maximum rate of pubescent elongation occurs earliest in Ba-N. There are no consistent sex diffe... | 269,160 | [
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The investigation of a recurrence of an AHC virus epidemic at Lucknow: a serosurvey for AHC virus antibodies before and after the epidemic. | An epidemic of acute haemorrhagic conjunctivitis (AHC) recurred at Lucknow during July to September 1975, after a gap of 4 years. Out of the 35 cases investigated thoroughly, 20 Entero-70-like cytopathogenic agents were isolated from the conjunctiva which were neutralized by antisera against AHC virus J670/71 of Japan.... | 269,197 | [
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... |
Prolongation of antibacterial activity of chlorhexidine adsorbed to teeth. Effect of sulfates. | The results suggest that the effectiveness of sulfates in prolonging the antibacterial activity of teeth treated with chlorhexidine gluconate is related to the acidity and concentration of the sulfate solutions. The acidity may contribute to the effectiveness by modifying the tooth surface for enhanced reaction with su... | 269,246 | [
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0.1613834,
0.004909238,
... |
Comparison of the efficacy of a questionnaire, oral history, and clinical examination in detecting signs and symptoms of occlusal and temporomandibular joint dysfunction. | A comparison of three methods of obtaining information relating to some TMJ signs and symptoms has been made. The taking of an oral history by this examiner was shown to be the least reliable. The acquisition of data by this verbal process is a clinically sophisticated and difficult medical procedure and a major source... | 269,280 | [
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0.1503842,
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... |
Myositis ossificans traumatica of the masseter muscle. Report of a case. | A case of myositis ossificans traumatica has been reported. Clinical, histopathologic, and roentgenographic entities have been referred to. An up-to-date review of the literature on this disorder has been presented. | 269,331 | [
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-0.1825807,
... |
Bacterial contamination and transmission by nitrous oxide sedation apparatus. | Microbial contamination of sterile nasal hoods was demonstrated in nine of twenty-one clinical administrations of nitrous oxide-oxygen conscious sedation. In each case, bacteria isolated from the hood after 30 minutes' use were correlated morphologically with organisms recovered from the subject's nasal mucosa. A labor... | 269,334 | [
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0.1487949,
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NECROTIZING SIALOMETAPLASIA. | Nonhealing palatal ulcerations in two white male patients, one 50 and another 58 years of age, were clinically suspected of being malignant, even after the initial biopsies were negative. Second biopsies in each case confirmed the original opinions, but the lesions were diagnosed specifically as "necrotizing sialometap... | 269,338 | [
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0.07299424,
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Dentin dysplasia, type II: a rare autosomal dominant disorder. | Dentin dysplasia, Type II, is a rare autosomal dominant disorder. The primary teeth are amber and translucent and the pulp chambers are obliterated. The permanent teeth have a normal to brown-gray coloration and a thistle-tube pulp configuration with multiple true denticles. To date, only five families with this disord... | 269,353 | [
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0.2048359,
0.1465728,
... |
[Odontological-surgical pathology in an Oslo population]. | The present report deals with an investigation concerning the distribution of dental pathology in an Oslo population. The diagnoses are based on roentgenological findings in orthopantomograms from 216 individuals participating in the screening. The investigation contributes to knowledge about pathological conditions of... | 269,366 | [
-0.02364453,
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0.3378205,
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0.4977576,
0.3429317,
-0.13271... |
Uterine peroxidase as a marker for estrogen action. | Administration of a single dose of estradiol to immature rats gives rise to the appearance of substantial amounts of peroxidase (donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7) enzyme activity in the uterus. This enzyme induction, which is inhibited by administration of actinomycin D and cycloheximide, can be dete... | 269,379 | [
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0.4124657,
0.2261841,
-0.06946087,
... |
Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol. | Benz[a]anthracene and the five metabolically possible vicinal trans dihydrodiols of benz[a]anthracene were tested for ability to initiate skin tumors in CD-1 female mice. A single topical application of 0.4-2.0 mumol of hydrocarbon was followed 18 days later by twice weekly applications of the skin promoter 12-O-tetrad... | 269,381 | [
-0.1679908,
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0.6008779,
0.4740907,
-0.1652355,
... |
Identification and cloning of the chloroplast gene coding for the large subunit of ribulose-1,5-bisphosphate carboxylase from Chlamydomonas reinhardi. | mRNA coding for the large subunit (LS) of ribulose-1,5-bisphosphate carboxylase [3-phospho-D-glycerate carboxy-lyase (dimerizing), EC 4.1.1.39] from Chlamydomonas reinhardi has been isolated from small polyribosomes immunoadsorbed to column-bound anti-LS antibody. 32P-Labeled LS mRNA was used as a hybridization probe t... | 269,382 | [
0.1555471,
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0.2126172,
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-... |
Evidence against phospholipid asymmetry in intracellular membranes from liver. | We have studied the distribution of phospholipids across the membrane of microsomal vesicles and Golgi-derived secretory vesicles from rat liver by the use of phospholipases. Model studies on single-bilayer phospholipid vesicles showed that phospholipase A2 (phosphatide 2-acyl-hydrolase, EC 3.1.1.4) cleaved at least 80... | 269,395 | [
-0.2460502,
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0.2233946,
0.4992142,
-0.07197288,
... |
Addition of colchicine--tubulin complex to microtubule ends: the mechanism of substoichiometric colchicine poisoning. | Colchicine blocks microtubule polymerization by an unusual substoichiometric poisoning mechanism. We have investigated the mechanism by which this poisoning occurs with several experimental approaches, and have found that colchicine acts by addition to microtubule ends as a colchicine-tubulin complex. | 269,406 | [
-0.1779613,
0.01768252,
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0.3191132,
0.3172283,
0.2484542,
0.07686572,
... |
Transfer of codominant markers by isolated metaphase chromosomes in Chinese hamster ovary cells. | Codominant mutations to methotrexate and ouabain resistance in Chinese hamster ovary cells can be transferred to recipient Chinese hamster ovary cells by isolated metaphase chromosomes. For methotrexate, both the structural change and the increased activity of dihydrofolate reductase (5,6,7,8-tetrahydrofolate:NADP+ oxi... | 269,408 | [
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0.262436,
0.1570481,
0.1238659,
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0... |
Fatty liver induced in Zucker "fatty" (ff) rats by a semisynthetic diet rich in sucrose. | A new fatty liver model is described in which heredity plays a major role. A marked fatty liver develops when the homozygous mutant Zucker rat (ff or "fatty") is fed a semi-synthetic diet enriched in sucrose. Lean littermates do not develop fatty livers on this experimental diet. Even old ff rats do not develop fatty l... | 269,413 | [
-0.009365339,
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0.003041425,
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0.4378779,
-0.1638... |
Enzyme replacement therapy in Gaucher's disease: large-scale purification of glucocerebrosidase suitable for human administration. | Enzyme replacement therapy for the alleviation of Gaucher's disease has been impeded because of the difficulty in preparing large amounts of glucocerebrosidase, the enzyme that is deficient in patients with this disorder. A large-scale procedure for the purification of human placental glucocerebrosidase has been develo... | 269,414 | [
-0.03913284,
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0.1371733,
0.1324634,
0.2608621,
-0.1114906,
... |
Succinyl concanavalin A stimulates and antimicrotubular drugs inhibit the synthesis of a brain-specific protein in rat glial cells. | The relative synthesis of the brain-specific s100 protein increased as clonal rat glial cells, C6, progressed from logarithmic to stationary growth in monolayer culture. Drugs that disrupt microtubules, such as colchicine, vinblastine, Colcemid, and podophyllotoxin, inhibited the relative synthesis of S100 protein in s... | 269,436 | [
-0.1071847,
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0.1298625,
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0.2462445,
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0.1531191,
0.005594552,
0.343077,
0.06200129,
... |
Dissociation of tumor promoter-stimulated ornithine decarboxylase activity and DNA synthesis in mouse epidermis in vivo and in vitro by fluocinolone acetonide, a tumor-promotion inhibitor. | 12-O-Tetradecanoyl phorbol-13-acetate (TPA), a tumor promoter, stimulates DNA synthesis in mouse epidermal cells in vivo and in vitro. This response appears to be mediated through polyamine metabolism because ornithine decarboxylase (L-ornithine carboxy-lyase, EC 4.1.1.17)activity is markedly increased shortly after pr... | 269,443 | [
-0.08275637,
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0.2792408,
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0.2465262,
0.3311246,
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-0.5172729,
... |
Mitotic activity of the granulopoietic precursor cells in the peripheral blood in chronic myeloid leukaemia. | The mitotic indices (MI) of granulopoietic precursor cells in peripheral blood and bone marrow were studied in 38 patients with typical chronic myeloid leukaemia (CML) in the chronic phase. The MI in the peripheral blood were very low, in the median 0.07%, compared to those in the bone marrow with a median of 1.07%. Th... | 269,493 | [
-0.04988463,
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0.2427732,
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0.4227579,
0.396228,
0.1271575,
0.1649142,
-0.0... |
A review of 700 bone marrow aspirations in Papua New Guinea. | A retrospective survey of 700 marrow examinations in Papua New Guinea in a 2 1/2 year period has been carried out. Over half of the total came from the Port Moresby General Hospital. Anaemia and splenomegaly were the commonest indications. A disturbing proportion of the specimens were unsatisfactory for interpretation.... | 269,575 | [
-0.2184807,
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0.2338666,
0.2965636,
-0.104876... |
Primary papillary carcinoma of the prostate: report of a histopathologic, cytologic and electron microscopic study on one case. | An unusual type of prostatic carcinoma is described. Histopathologic examination showed a papillary and acinar appearance. Aspiration cytology showed papillary fragments and sheets of malignant cells. The ultrastructural features of this tumor were similar to those reported for prostatic carcinoma rather than endometri... | 269,605 | [
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0.4565382,
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0.2530231,
-0.0352958,
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Cytogenetic studies of human endometrial carcinomas by means of tissue culture. | The cytogenetic studies of human endometrial carcinomas were performed using a tissue culture technique. Seventeen cases or 40.5 per cent out of 42 trials for culture could be analyzed. The mode of chromosome number was found at the diploid range in all cases, and the exact counting of the modal range revealed that the... | 269,609 | [
-0.1891892,
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0.02629953,
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0.4365914,
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0.13... |
McArdle's syndrome. Fine structural changes in muscle. | Two cases of McArdle's syndrome are reported. One is a "classical" example; the other is unusual because of the in vitro presence of muscle phosphorylase activity. In the latter case, the electronmicroscopic investigation confirmed the diagnosis. The fine structural changes characteristic of this disease are summarized... | 269,622 | [
-0.3157513,
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0.1791294,
... |
A photographic study of the soft-tissue profile of the Negro population. | The present investigation was undertaken to compare the Ricketts, Steiner, and Holdaway soft-tissue values to the Negro individual. The study involved the photographs of more than 1,000 North American Negroes, (500 males and 500 females). One-hundred of the most attractive were selected by a group of judges of differen... | 269,666 | [
0.1174183,
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0.2422914,
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... |
A cheap oral therapy for Paget's disease of bone. | Nine patients with painful Paget's disease of bone were treated for 200 days with a drug combination designed to elevated plasma calcium, hence stimulating the production of endogenous calcitoning and suppressing that of parathyroid hormone. This combination was oral calcium, a thiazide diuretic, a low phosphorus diet ... | 269,686 | [
-0.3243283,
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0.103302,
0.3510558,
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... |
The Laurence-Moon-Biedl syndrome in a Singhalese family. | The first published occurrence of the Laurence-Moon-Biedl Syndrome in a Singhalese family is reported. Three members of a family of six with first cousin non-affected parents are described along with studies to indicate that the hypogonadism in this family can be ascribed to hypogonadotrophism. The high incidence of co... | 269,692 | [
0.03131829,
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0.0739583... |
Microsurgical vasovasostomy: a reliable vasectomy reversal. | Optimal results of repair of a severed tube can be expected when a meticulous atraumatic microsurgical technique is based on a detailed knowledge of the anatomy and function of the tube. A reliable vas repair after vasectomy involves the avoidance of leakage or scarring in a tube of which the ends differ in internal di... | 269,700 | [
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0.2340732,
0.1015212,
... |
Clinical experience with Samoans in Auckland, New Zealand. | Samoans constitute the second largest ethnic Polynesian minority group in New Zealand. Generally, this is a socially and culturally deprived group from a European viewpoint. Causative factors of social and emotional stress and coping mechanisms are described. A number of culturally determined syndromes are encountered ... | 269,718 | [
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0.06436081,
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0.2663521,
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0.1869722,
-0.041855... |
Relationship between sociomedical factors and TMJ-symptoms in Norwegians with myofascial pain-dysfunction syndrome. | The relationship between background characteristics, stress, reported symptoms and clinical findings was studied in a group comprising 333 patients with Myofascial Pain Dysfunction Syndrome (MPD). Three-quarters of this clientele were women, most of them of young or middle age. The stressors most frequently reported we... | 269,766 | [
-0.02579766,
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0.07951152,
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-0.21... |
Study of a fissure sealant in mentally retarded Canadian children. | The occlusal fissure of 812 permanent and primary posterior teeth of 160 retarded children were sealed with a fluid resin which was polymerized with an ultra-voilet lamp. A half mouth technique was used to evaluate the effectiveness of the sealant in the prevention of fissure caries. The 1st year, the sealant was retai... | 269,768 | [
-0.008243741,
0.4736329,
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0.1362783,
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0.2844848,
0.234381,
0.02387965,
0... |
A correlation study of diet, oral hygiene and dental caries in 457 Canadian children. | The interrelationship of diet, oral hygiene and caries was evaluated. Of the sample size of 457 children, 234 were in grade 1 and 223 grade 7. Five-day diet surveys were obtained, followed by clinical examinations for oral hygiene and caries. One examiner, using mouth mirror, explorer and extraoral light, conducted the... | 269,769 | [
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0.06131706,
... |
Enamel mottling in a high strontium area of the U.S.A. | As part of an epidemiologic study conducted in seven towns in Wisconsin, U.S.A., enamel mottling, opacities, and pigmentations were assessed in 1, 313 12- to 14-year-old schoolchildren. Enamel mottling was found to increase in prevalence and severity as strontium concentrations in communal drinking water increased. Thi... | 269,771 | [
-0.4061674,
0.1266934,
0.01767725,
-0.2326666,
-0.3253645,
-0.2693484,
-0.2468236,
0.05663995,
0.1063587,
-0.1607233,
0.291264,
0.2058754,
-0.001450334,
0.02277558,
0.2395615,
-0.08440698,
0.02882758,
0.06660353,
0.06950848,
-0.2122179,
0.1582623,
0.2237413,
-0.1511041,
... |
Effect of leupeptin on induction of lymphoblastic leukemia in mice by N-nitrosobutylurea. | The effect of leupeptin on the induction of lymphoblastic leukemia in ICR/JCL female mice by N-nitrosobutylurea (NBU) was investigated. NBU was given as a 0.02% solution in drinking water for 10 weeks. A 0.1% concentration of leupeptin was given in the diet. Group A was fed on the leupeptin diet from the beginning, Gro... | 269,841 | [
0.0571405,
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0.2785717,
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0.1502758,
0.2154191,
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0.5989138,
0.02712873,
0.2869125,
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0.3252296,
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0.2115522,
0.1749973,
0.004807443,
-0.0554695... |
Panoramic radiography in dentistry. | Examples of panoramic radiography equipment in use are briefly reviewed and the differences pointed out between those operating on the principle of tomography and other "panoramic" instruments. The various uses to which panoramic radiography is put are described and the problems involved in using them explained. The ad... | 269,848 | [
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0.336391,
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0.2342796,
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0.3572052,
0.01082252,
-0.05822895... |
Correlates of dentists' attitudes toward continuing education in TEAM. | All dentists in active practice in Rhode Island were surveyed to determine their attitudes toward continuing education in TEAM. A total of 74.6 percent of those surveyed responded to the questionnaire. Only one variable, location in a building with other dental offices, was found to be associated with a perceived need ... | 269,858 | [
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0.1342832,
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0.03411917,
0.2798246,
0.008689837,
0.4404103,
0.06706048,
0.2064317,... |
Thrombotic thrombocytopenic purpura: report of case. | TTP is an acute, usually fatal disease of unknown etiology. Diagnostic confirmation of the disease requires histologic demonstration of the deposition of hyaline thrombi within the lumens of arterioles and capillaries in the absence of vasculitis. The clinical, laboratory, and histological manifestations of TTP were re... | 269,938 | [
-0.08115244,
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0.1779928,
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0.08574983,
0.1711284,
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0.04829706,
0.5550159,
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0.1139168,
0.03966715,
0.05493024,
0.3401707,
0.1745808,
-0.020204... |
Blood supply of human gingiva following periodontal surgery. A fluorescein angiographic study. | This study demonstrates changes in the gingival vascular supply of humans following various periodontal surgical procedures. A special system was used to photograph circulatory changes following an i.v. injection of sodium fluorescein to visualize blood supply. The results of this study suggest that the following conce... | 269,943 | [
-0.09942601,
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0.2072081,
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0.229115,
0.3085476,
0.07211785,
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0.009478019,
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0.02689841,
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0.2200677,
0.01998677,
0.2408714,
0.4014874,
0.371518,
0.05408714,
... |
Let /S/ be your guide. | New guidelines for establishing the vertical dimension of occlusion have been reviewed. They are based upon the fact that the body of the mandible assumes an easily recordable, repetitive horizontal and vertical position when the patient is at the /S/ position during speech. This controlled method of developing vertica... | 269,949 | [
-0.3857344,
0.3313193,
0.199261,
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0.232338,
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0.05196061,
0.1214253,
0.1829679,
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-0.0741831,
0.07851277,
-0.4067504,
-0.008823944,
0.1457959,
-0.01489138,
-0.087583... |
Improvement of preparative conditions for cytogenetic studies by short-term liquid culture of haemopoietic cells. | In patients with haemopoietic failure, the low incidence of cells in mitosis often prevents successful chromosome preparations. By performing liquid cultures of myeloid cells a high incidence of mitoses could be obtained even in those cases failing to provide mitoses when the direct preparation technique was used. The ... | 269,983 | [
0.01304998,
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0.1248695,
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0.1225504,
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0.06957008,
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0.07509053,
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0.314773,
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0.0128996,
-0.1376117,
-0.1660088,
0.158989,
0.5112746,
-0.02055657,
-0.048331... |
The radiology of bone and soft tissue sarcomas. | Solitary lesions of bone often have characteristic radiographic patterns that suggest the diagnosis of a specific bone tumor. Differentiation of tumor from infection, however, frequently may be impossible, and the majority of bone lesions require biopsy for histologic confirmation of the type of tumor or for identifica... | 270,087 | [
-0.2440842,
0.1073418,
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0.004531666,
0.1322059,
0.1767603,
-0.1051759,
-0.2081296,
-0.02058278,
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-0.3025011,
-0.2863078,
0.119829,
0.4169786,
0.04969696,
0.1197959,
0.0081816,
-0.2870312,
... |
[Bite plates and occlusal splints]. | Occlusal adjustments are often necessary in cases of masticatory muscle spasm, bruxism, traumatic occlusion and TMJ disturbancies. Before such occlusal adjustments are performed, the patient should either wear a bite plate or an occlusal splint which frees the occlusion for a certain time. The splint is fabricated on a... | 270,217 | [
-0.000469144,
0.5509717,
0.2405851,
0.2606992,
0.07997847,
-0.2178902,
-0.3316444,
-0.1402774,
0.2342941,
-0.007308063,
0.04615777,
-0.2589984,
-0.08079803,
-0.5058011,
-0.9039797,
-0.2634304,
-0.4299923,
0.4589195,
-0.240158,
-0.1822533,
0.2187387,
-0.4390962,
-0.1516258... |
[The mechanism of cell proliferation in acute (immature-cell) leukemia]. | In 40 patients with acute leukaemias the 3H-thymidine and mitosis indices were determined in the population of blast cells in bone marrow and the cellularity of bone marrow was determined. The studies were carried out in the first episode of the disease before treatment and in some patients (13) they were repeated duri... | 270,271 | [
-0.02386819,
-0.2607318,
0.1088756,
-0.146041,
0.2119601,
-0.3795883,
-0.3797207,
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0.05622183,
-0.01867506,
0.05101662,
-0.2906128,
0.26548,
-0.6836177,
-0.3000688,
-0.3309618,
-0.04803172,
-0.199393,
0.5060524,
0.7572359,
-0.1876308,
-0.203558,
... |
A new parallel plate dialyser. III. Preliminary experience on clinical performance. | The clinical model of a new parallel plate dialyser with a membrane area of 0.96 m2 with cuprophane 150 PM has been tested in more than 2000 dialyses with good clinical results. The simple design permits an aseptic, semiautomatic assembly and makes cheap industrial production possible. Clinical clearance values for ure... | 270,279 | [
-0.2882924,
0.1721401,
0.1607805,
0.00004240777,
0.04664664,
-0.2987815,
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0.04321547,
0.2164794,
0.2085128,
0.02573107,
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0.1874889,
0.170538,
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-0.1273093,
-0.3939051,
0.1831991,
0.1256997,
-0.139541,
-0.1430938,
... |
Immediate tonsillectomy for the treatment of peritonsillar abscess. | Our experience with 119 cases of peritonsillar abscess supports the experience of others, that immediate tonsillectomy is a safe treatment which provides prompt, complete drainage of the abscess. There was one episode of immediate postoperative hemorrhage and one of delayed bleeding, but there were no anesthetic compli... | 270,291 | [
-0.1863218,
0.01157399,
-0.2924416,
-0.004936152,
0.03786584,
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-0.2056353,
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0.2126199,
0.02702774,
0.3194001,
-0.1972544,
-0.2175677,
0.06746298,
-0.2231552,
-0.1578511,
-0.06386919,
-0.2945411,
-0.3664202,
0.3402757,
-0.1192949,
0.010541... |
The mandibular dental arch: Part I, lower incisor position. | The position of the lower incisor with respect to hard tissue references has been evaluated. Two samples were used for this purpose: one containing 78 patients with posttreatment records having a postretention period of at least 4 years, and the other composed of 82 normal occlusions. The results indicated: 1) There wa... | 270,296 | [
-0.06012366,
0.5520327,
-0.01914209,
-0.2860649,
0.1426329,
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0.1180042,
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0.1563919,
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0.046073,
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0.2570273,
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-0.1285364,
0.07410979,
-0.1047667,
-0.1857025,
... |
The role of dental compensations in the orthodontic treatment of mandibular prognathism. | Thirty-six patients with orthodontically treated mandibular prognathism were recalled for cephalometric and clinical evaluation. A comparison group of 32 non-Class III patients was similarly examined. Analysis of variables associated with the anterior dentition and documentationtion of labial gingival recession and too... | 270,298 | [
-0.2310711,
0.3648006,
-0.1492374,
-0.05719214,
0.2283956,
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-0.05312915,
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-0.1732041,
0.0003506048,
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-0.3100262,
0.1640491,
0.1975985,
-0.3443663,
-0.3115513,
0.04825648,
0.03226288,
0.000... |
Assessment of drug sensitivity of human leukaemic myeloblasts. II. The toxic effects of cytosine arabinoside on 125IUdR-labelled human leukaemic myeloblasts in mice. | Leukaemia cells from the peripheral blood and bone marrow of patients with acute myeloblastic leukaemia were labelled in vitro with [125I]5-iodo-2'-deoxy-uridine (IUdR). The myeloblasts were then injected into groups of mice and the survival of these cells estimated by measuring isotope loss, using whole-body counting.... | 270,373 | [
-0.2618196,
-0.4748125,
-0.1537236,
-0.1912958,
0.4911661,
0.04155365,
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0.2538321,
0.1368026,
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0.3138544,
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0.3401294,
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0.3956202,
-0.4894525,
0.3911827,
0.31407,
0.04745196,
0.1114237,
-0... |
[Extracellular polysaccharides from Streptococcus mutans of various biotypes--chemical characterization and enzymatic hydrolysis]. | The composition and proportions of different types of compound were established in extracellular polysaccharides synthesized in virto by streptococcus mutans strains of various biotypes. The polysaccharides were further enzymatically hydrolysed with dextranase and the degree of hydrolysis as well as the character and a... | 270,401 | [
0.02044198,
0.3987227,
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0.1766491,
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0.05366954,
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0.005922166,
-0.1172932,
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-0.2918694,
0.3263249,
0.2586783,
0.0458952,
0.725077,
0.3055688,
-0.220674,
0.2... |
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